1-247588140-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588140
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588140
    reference: chr 1
allele count: 354
allele frequency: 2.952164920942024e-3
allele num: 119912
alternate allele: T
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1570C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1395C>T
  hgvsp: ENST00000366497.2:c.1395C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1395C>T
  hgvsp: ENST00000366496.2:c.1395C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1395C>T
  hgvsp: ENST00000336119.3:c.1395C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1395C>T
  hgvsp: ENST00000348069.2:c.1395C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1395C>T
  hgvsp: ENST00000391827.2:c.1395C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1395C>T
  hgvsp: ENST00000391828.3:c.1395C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1666
  bin: 4.75e1
  variant carriers: 33
genotype depth: GenotypeDepth
  all individuals: 1184
  bin: 5.25e1
  variant carriers: 28
genotype depth: GenotypeDepth
  all individuals: 1641
  bin: 1.25e1
  variant carriers: 11
genotype depth: GenotypeDepth
  all individuals: 13680
  bin: 3.25e1
  variant carriers: 52
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 5140
  bin: 3.75e1
  variant carriers: 42
genotype depth: GenotypeDepth
  all individuals: 21949
  bin: 2.75e1
  variant carriers: 37
genotype depth: GenotypeDepth
  all individuals: 86
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1963
  bin: 1.75e1
  variant carriers: 12
genotype depth: GenotypeDepth
  all individuals: 497
  bin: 6.25e1
  variant carriers: 15
genotype depth: GenotypeDepth
  all individuals: 2925
  bin: 4.25e1
  variant carriers: 51
genotype depth: GenotypeDepth
  all individuals: 758
  bin: 5.75e1
  variant carriers: 26
genotype depth: GenotypeDepth
  all individuals: 51
  bin: 9.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 7757
  bin: 2.25e1
  variant carriers: 11
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 28
  bin: 9.25e1
  variant carriers: 5
genotype quality: GenotypeQuality
  all individuals: 828
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3871
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 631
  bin: 4.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 10
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 113
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 619
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 58
  bin: 1.25e1
  variant carriers: 0
hgvs: p.His465His
num of homozygotes: 2
population: Latino
population: Other
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: South Asian
population: East Asian
reference allele: C
site quality: ClippingRankSum
site quality: MQRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: QD
site quality: ReadPosRankSum
site quality: DP
site quality: BaseQRankSum
site quality: VQSLOD
site quality: MQ

http://identifiers.org/exac.variant/1-247588141-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588141
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588141
    reference: chr 1
allele count: 1
allele frequency: 8.342927700188551e-6
allele num: 119862
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1396C>A
  hgvsp: ENSP00000355453.2:p.Leu466Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1396C>A
  hgvsp: ENSP00000337383.3:p.Leu466Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1396C>A
  hgvsp: ENSP00000375703.2:p.Leu466Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1396C>A
  hgvsp: ENSP00000355452.2:p.Leu466Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1571C>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1396C>A
  hgvsp: ENSP00000375704.3:p.Leu466Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1396C>A
  hgvsp: ENSP00000294752.3:p.Leu466Ile
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1164
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5112
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13656
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1649
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 736
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2084
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7808
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 91
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1641
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2892
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 644
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 21930
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 633
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5823
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 3883
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 922
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 874
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1254
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3934
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9829
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 809
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Leu466Ile
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: African
population: South Asian
population: East Asian
population: European (Non-Finnish)
population: Other
reference allele: C
site quality: DP
site quality: QD
site quality: ClippingRankSum
site quality: FS
site quality: VQSLOD
site quality: MQRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: ReadPosRankSum

1-247588152-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588152
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588152
    reference: chr 1
allele count: 41
allele frequency: 3.422084967865788e-4
allele num: 119810
alternate allele: T
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1407C>T
  hgvsp: ENST00000366497.2:c.1407C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1407C>T
  hgvsp: ENST00000336119.3:c.1407C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1407C>T
  hgvsp: ENST00000366496.2:c.1407C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1407C>T
  hgvsp: ENST00000391827.2:c.1407C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1407C>T
  hgvsp: ENST00000348069.2:c.1407C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1407C>T
  hgvsp: ENST00000391828.3:c.1407C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1582C>T
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1621
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 95
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 73
  bin: 8.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 23
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5066
  bin: 3.75e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 8384
  bin: 2.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 21829
  bin: 2.75e1
  variant carriers: 7
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 13377
  bin: 3.25e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 1953
  bin: 1.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2869
  bin: 4.25e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 105
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1164
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 735
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 674
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1639
  bin: 4.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 176
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1305
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 117
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 415
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 629
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5841
  bin: 9.75e1
  variant carriers: 40
genotype quality: GenotypeQuality
  all individuals: 748
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2459
  bin: 8.25e1
  variant carriers: 0
hgvs: p.Leu469Leu
num of homozygotes: 0
population: East Asian
population: African
population: European (Finnish)
population: Latino
population: South Asian
population: European (Non-Finnish)
population: Other
reference allele: C
site quality: QD
site quality: ClippingRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: BaseQRankSum
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQ
site quality: DP

1-247588161-G-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588161
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588161
    reference: chr 1
allele count: 2
allele frequency: 1.670034569715593e-5
allele num: 119758
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1416G>T
  hgvsp: ENSP00000355452.2:p.Leu472Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1416G>T
  hgvsp: ENSP00000375704.3:p.Leu472Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1416G>T
  hgvsp: ENSP00000294752.3:p.Leu472Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1416G>T
  hgvsp: ENSP00000355453.2:p.Leu472Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1416G>T
  hgvsp: ENSP00000375703.2:p.Leu472Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1591G>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1416G>T
  hgvsp: ENSP00000337383.3:p.Leu472Phe
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 8790
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1532
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1635
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 694
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 97
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5036
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 21735
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2857
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1836
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13300
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 735
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 107
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 16
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 85
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2450
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1183
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 587
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3762
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 767
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 693
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Leu472Phe
num of homozygotes: 0
population: East Asian
population: Other
population: Latino
population: South Asian
population: African
population: European (Non-Finnish)
population: European (Finnish)
reference allele: G
site quality: ClippingRankSum
site quality: MQRankSum
site quality: QD
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: MQ
site quality: BaseQRankSum
site quality: FS
site quality: DP

http://identifiers.org/exac.variant/1-247588191-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588191
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588191
    reference: chr 1
allele count: 2
allele frequency: 1.666916704172292e-5
allele num: 119982
alternate allele: A
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1446C>A
  hgvsp: ENST00000336119.3:c.1446C>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1446C>A
  hgvsp: ENST00000391827.2:c.1446C>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1446C>A
  hgvsp: ENST00000366496.2:c.1446C>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1621C>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1446C>A
  hgvsp: ENST00000348069.2:c.1446C>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1446C>A
  hgvsp: ENST00000366497.2:c.1446C>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1446C>A
  hgvsp: ENST00000391828.3:c.1446C>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 735
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1110
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10204
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 77
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 945
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22007
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2840
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4983
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 619
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1636
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13093
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 29097
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 962
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 276
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 477
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 41
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 76
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3751
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2420
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9740
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Ile482Ile
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: African
population: European (Non-Finnish)
population: South Asian
population: Other
population: East Asian
reference allele: C
site quality: ReadPosRankSum
site quality: MQ
site quality: VQSLOD
site quality: QD
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: FS
site quality: BaseQRankSum
site quality: DP
site quality: ClippingRankSum

1-247588191-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588191
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588191
    reference: chr 1
allele count: 1
allele frequency: 8.334583520861462e-6
allele num: 119982
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1446C>G
  hgvsp: ENSP00000355453.2:p.Ile482Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1446C>G
  hgvsp: ENSP00000355452.2:p.Ile482Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1446C>G
  hgvsp: ENSP00000375704.3:p.Ile482Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1621C>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1446C>G
  hgvsp: ENSP00000375703.2:p.Ile482Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1446C>G
  hgvsp: ENSP00000337383.3:p.Ile482Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1446C>G
  hgvsp: ENSP00000294752.3:p.Ile482Met
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1636
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10204
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 77
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 735
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 945
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 619
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22007
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1110
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2840
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 23
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13093
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4983
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 29097
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2420
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 55
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3751
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9740
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 165
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 477
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 359
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1168
  bin: 8.75e1
  variant carriers: 0
hgvs: p.Ile482Met
num of homozygotes: 0
population: East Asian
population: Other
population: African
population: European (Non-Finnish)
population: Latino
population: South Asian
population: European (Finnish)
reference allele: C
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: QD
site quality: ClippingRankSum
site quality: MQRankSum
site quality: DP
site quality: FS
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQ

1-247588200-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588200
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588200
    reference: chr 1
allele count: 1
allele frequency: 8.327781479013991e-6
allele num: 120080
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1455G>A
  hgvsp: ENST00000391828.3:c.1455G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1455G>A
  hgvsp: ENST00000366497.2:c.1455G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1455G>A
  hgvsp: ENST00000348069.2:c.1455G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1455G>A
  hgvsp: ENST00000391827.2:c.1455G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1455G>A
  hgvsp: ENST00000366496.2:c.1455G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1455G>A
  hgvsp: ENST00000336119.3:c.1455G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1630G>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 580
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 752
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10413
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4979
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 898
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22256
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2837
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13097
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 737
  bin: 5.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 67
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1635
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1164
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3716
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 242
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 36
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3748
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 318
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9785
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Glu485Glu
num of homozygotes: 0
population: European (Finnish)
population: South Asian
population: Other
population: African
population: East Asian
population: Latino
population: European (Non-Finnish)
reference allele: G
site quality: MQ
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: MQRankSum
site quality: BaseQRankSum
site quality: DP
site quality: QD
site quality: VQSLOD
site quality: FS
site quality: ReadPosRankSum

1-247588206-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588206
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588206
    reference: chr 1
allele count: 16
allele frequency: 1.331668747399085e-4
allele num: 120150
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1461C>T
  hgvsp: ENST00000391828.3:c.1461C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1636C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1461C>T
  hgvsp: ENST00000391827.2:c.1461C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1461C>T
  hgvsp: ENST00000366496.2:c.1461C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1461C>T
  hgvsp: ENST00000366497.2:c.1461C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1461C>T
  hgvsp: ENST00000336119.3:c.1461C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1461C>T
  hgvsp: ENST00000348069.2:c.1461C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 57
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 665
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1638
  bin: 4.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 484
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 541
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10588
  bin: 2.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 701
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4996
  bin: 3.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 736
  bin: 5.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 2841
  bin: 4.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 22336
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 13148
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 207
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9785
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2414
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 19
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 29962
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 243
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 316
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 35
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3756
  bin: 7.25e1
  variant carriers: 0
hgvs: p.Ser487Ser
num of homozygotes: 0
population: European (Non-Finnish)
population: Latino
population: European (Finnish)
population: African
population: East Asian
population: South Asian
population: Other
reference allele: C
site quality: MQRankSum
site quality: DP
site quality: QD
site quality: FS
site quality: MQ
site quality: BaseQRankSum
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum

1-247588214-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588214
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588214
    reference: chr 1
allele count: 71
allele frequency: 5.902696950550365e-4
allele num: 120284
alternate allele: A
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1469G>A
  hgvsp: ENSP00000375703.2:p.Arg490Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1644G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1469G>A
  hgvsp: ENSP00000355453.2:p.Arg490Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1469G>A
  hgvsp: ENSP00000294752.3:p.Arg490Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1469G>A
  hgvsp: ENSP00000337383.3:p.Arg490Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1469G>A
  hgvsp: ENSP00000355452.2:p.Arg490Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1469G>A
  hgvsp: ENSP00000375704.3:p.Arg490Lys
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10834
  bin: 2.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 347
  bin: 6.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 391
  bin: 1.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 504
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 515
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4973
  bin: 3.75e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 22574
  bin: 2.75e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 13174
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1174
  bin: 5.25e1
  variant carriers: 12
genotype depth: GenotypeDepth
  all individuals: 738
  bin: 5.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2837
  bin: 4.25e1
  variant carriers: 11
genotype depth: GenotypeDepth
  all individuals: 1639
  bin: 4.75e1
  variant carriers: 10
genotype quality: GenotypeQuality
  all individuals: 211
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 153
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 132
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 128
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 202
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3722
  bin: 7.75e1
  variant carriers: 0
hgvs: p.Arg490Lys
num of homozygotes: 0
population: African
population: European (Finnish)
population: Latino
population: East Asian
population: European (Non-Finnish)
population: South Asian
population: Other
reference allele: G
site quality: DP
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: MQ
site quality: FS
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: QD
site quality: MQRankSum
site quality: VQSLOD

1-247588214-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588214
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588214
    reference: chr 1
allele count: 1
allele frequency: 8.313657676831499e-6
allele num: 120284
alternate allele: C
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1469G>C
  hgvsp: ENSP00000355452.2:p.Arg490Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1469G>C
  hgvsp: ENSP00000355453.2:p.Arg490Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1469G>C
  hgvsp: ENSP00000337383.3:p.Arg490Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1469G>C
  hgvsp: ENSP00000375703.2:p.Arg490Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1469G>C
  hgvsp: ENSP00000294752.3:p.Arg490Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1644G>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1469G>C
  hgvsp: ENSP00000375704.3:p.Arg490Thr
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 738
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4973
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22574
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 515
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13174
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10834
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 504
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2837
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1639
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 347
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1174
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 483
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 391
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 128
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 21
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 101
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2411
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3796
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1160
  bin: 8.75e1
  variant carriers: 0
hgvs: p.Arg490Thr
num of homozygotes: 0
population: European (Non-Finnish)
population: African
population: Other
population: South Asian
population: European (Finnish)
population: Latino
population: East Asian
reference allele: G
site quality: DP
site quality: QD
site quality: ClippingRankSum
site quality: MQRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: FS
site quality: BaseQRankSum
site quality: ReadPosRankSum

1-247588229-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588229
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588229
    reference: chr 1
allele count: 1
allele frequency: 8.302337938363443e-6
allele num: 120448
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1484A>G
  hgvsp: ENSP00000355453.2:p.Gln495Arg
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1659A>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1484A>G
  hgvsp: ENSP00000355452.2:p.Gln495Arg
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1484A>G
  hgvsp: ENSP00000294752.3:p.Gln495Arg
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1484A>G
  hgvsp: ENSP00000337383.3:p.Gln495Arg
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1484A>G
  hgvsp: ENSP00000375703.2:p.Gln495Arg
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1484A>G
  hgvsp: ENSP00000375704.3:p.Gln495Arg
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1630
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2822
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13227
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 381
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10987
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 734
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 231
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 433
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 43
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22792
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4969
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3829
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 88
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 67
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 45
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 123
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 86
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3755
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 563
  bin: 2.25e1
  variant carriers: 0
hgvs: p.Gln495Arg
num of homozygotes: 0
population: European (Non-Finnish)
population: South Asian
population: Latino
population: African
population: European (Finnish)
population: Other
population: East Asian
reference allele: A
site quality: VQSLOD
site quality: FS
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: MQRankSum
site quality: BaseQRankSum
site quality: DP
site quality: ReadPosRankSum
site quality: MQ
site quality: QD

1-247588235-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588235
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588235
    reference: chr 1
allele count: 1
allele frequency: 8.297653423611802e-6
allele num: 120516
alternate allele: T
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1665C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1490C>T
  hgvsp: ENSP00000337383.3:p.Ala497Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1490C>T
  hgvsp: ENSP00000375704.3:p.Ala497Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1490C>T
  hgvsp: ENSP00000355452.2:p.Ala497Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1490C>T
  hgvsp: ENSP00000294752.3:p.Ala497Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1490C>T
  hgvsp: ENSP00000375703.2:p.Ala497Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1490C>T
  hgvsp: ENSP00000355453.2:p.Ala497Val
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 22837
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 330
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13243
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11045
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 481
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 4968
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 41
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 203
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2826
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 393
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 734
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31232
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1160
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10001
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 502
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5769
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 53
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 23
  bin: 1.75e1
  variant carriers: 0
hgvs: p.Ala497Val
num of homozygotes: 0
population: African
population: Other
population: Latino
population: East Asian
population: European (Finnish)
population: European (Non-Finnish)
population: South Asian
reference allele: C
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: MQRankSum
site quality: VQSLOD
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: QD
site quality: DP

1-247588236-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588236
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588236
    reference: chr 1
allele count: 4
allele frequency: 3.3178500331785e-5
allele num: 120560
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1491G>A
  hgvsp: ENST00000366496.2:c.1491G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1491G>A
  hgvsp: ENST00000391827.2:c.1491G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1491G>A
  hgvsp: ENST00000336119.3:c.1491G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1491G>A
  hgvsp: ENST00000391828.3:c.1491G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1491G>A
  hgvsp: ENST00000366497.2:c.1491G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1491G>A
  hgvsp: ENST00000348069.2:c.1491G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1666G>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 313
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4970
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 39
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22859
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 196
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11056
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13247
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 379
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 481
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2824
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1631
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 23
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 98
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 57
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31266
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9998
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1408
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 41
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Ala497Ala
num of homozygotes: 0
population: South Asian
population: East Asian
population: African
population: Other
population: Latino
population: European (Finnish)
population: European (Non-Finnish)
reference allele: G
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: DP
site quality: FS
site quality: MQRankSum
site quality: QD
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: ClippingRankSum

1-247588257-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588257
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588257
    reference: chr 1
allele count: 1
allele frequency: 8.278693953241936e-6
allele num: 120792
alternate allele: A
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1512G>A
  hgvsp: ENST00000336119.3:c.1512G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1512G>A
  hgvsp: ENST00000391827.2:c.1512G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1512G>A
  hgvsp: ENST00000348069.2:c.1512G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1512G>A
  hgvsp: ENST00000366496.2:c.1512G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1512G>A
  hgvsp: ENST00000366497.2:c.1512G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1687G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1512G>A
  hgvsp: ENST00000391828.3:c.1512G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 143
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11113
  bin: 2.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13272
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 243
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 264
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23022
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2824
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 37
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4971
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 41
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 84
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 18
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1409
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5769
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 31492
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1160
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 48
  bin: 5.75e1
  variant carriers: 0
hgvs: p.Arg504Arg
num of homozygotes: 0
population: European (Non-Finnish)
population: African
population: Other
population: Latino
population: East Asian
population: South Asian
population: European (Finnish)
reference allele: G
site quality: FS
site quality: ClippingRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: QD
site quality: BaseQRankSum
site quality: VQSLOD
site quality: MQ

1-247588287-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588287
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588287
    reference: chr 1
allele count: 1
allele frequency: 8.269930532583527e-6
allele num: 120920
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1542C>T
  hgvsp: ENST00000348069.2:c.1542C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1542C>T
  hgvsp: ENST00000336119.3:c.1542C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1717C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1542C>T
  hgvsp: ENST00000391828.3:c.1542C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1542C>T
  hgvsp: ENST00000366497.2:c.1542C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1542C>T
  hgvsp: ENST00000366496.2:c.1542C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1542C>T
  hgvsp: ENST00000391827.2:c.1542C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 201
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 211
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23140
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 734
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2831
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11009
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 32
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13283
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 208
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4975
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3846
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 23
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 64
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 79
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 14
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 71
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31500
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1409
  bin: 9.25e1
  variant carriers: 0
hgvs: p.Cys514Cys
num of homozygotes: 0
population: Other
population: European (Non-Finnish)
population: South Asian
population: East Asian
population: Latino
population: African
population: European (Finnish)
reference allele: C
site quality: FS
site quality: MQRankSum
site quality: DP
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: MQ
site quality: VQSLOD

1-247588293-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588293
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588293
    reference: chr 1
allele count: 1
allele frequency: 8.268973158913126e-6
allele num: 120934
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1723G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1548G>A
  hgvsp: ENST00000391827.2:c.1548G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1548G>A
  hgvsp: ENST00000391828.3:c.1548G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1548G>A
  hgvsp: ENST00000348069.2:c.1548G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1548G>A
  hgvsp: ENST00000336119.3:c.1548G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1548G>A
  hgvsp: ENST00000366497.2:c.1548G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1548G>A
  hgvsp: ENST00000366496.2:c.1548G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13268
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23153
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11021
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 205
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 29
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 222
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4970
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 196
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2827
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 77
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3754
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5771
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 75
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31502
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2427
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 29
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 79
  bin: 4.75e1
  variant carriers: 0
hgvs: p.Lys516Lys
num of homozygotes: 0
population: Latino
population: African
population: East Asian
population: European (Finnish)
population: Other
population: South Asian
population: European (Non-Finnish)
reference allele: G
site quality: MQ
site quality: BaseQRankSum
site quality: VQSLOD
site quality: FS
site quality: ReadPosRankSum
site quality: DP
site quality: ClippingRankSum
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: QD

1-247588320-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588320
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588320
    reference: chr 1
allele count: 1
allele frequency: 8.267332462507647e-6
allele num: 120958
alternate allele: T
annotation: Annotation
  canonical: true
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1575C>T
  hgvsp: ENST00000336119.3:c.1575C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1575C>T
  hgvsp: ENST00000348069.2:c.1575C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1575C>T
  hgvsp: ENST00000391828.3:c.1575C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1575C>T
  hgvsp: ENST00000391827.2:c.1575C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1750C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1575C>T
  hgvsp: ENST00000366496.2:c.1575C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1575C>T
  hgvsp: ENST00000366497.2:c.1575C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4967
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 734
  bin: 5.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2825
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 307
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13276
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23134
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10924
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 198
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 232
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 103
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 23
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2425
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 72
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 294
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5769
  bin: 9.75e1
  variant carriers: 1
hgvs: p.Phe525Phe
num of homozygotes: 0
population: Other
population: South Asian
population: East Asian
population: European (Finnish)
population: African
population: Latino
population: European (Non-Finnish)
reference allele: C
site quality: FS
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: MQRankSum
site quality: QD
site quality: DP

1-247588333-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588333
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588333
    reference: chr 1
allele count: 1
allele frequency: 8.267742575567167e-6
allele num: 120952
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1588G>C
  hgvsp: ENSP00000375703.2:p.Ala530Pro
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1588G>C
  hgvsp: ENSP00000355452.2:p.Ala530Pro
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1588G>C
  hgvsp: ENSP00000294752.3:p.Ala530Pro
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1588G>C
  hgvsp: ENSP00000337383.3:p.Ala530Pro
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1588G>C
  hgvsp: ENSP00000355453.2:p.Ala530Pro
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1763G>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1588G>C
  hgvsp: ENSP00000375704.3:p.Ala530Pro
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 10903
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 366
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 191
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 28
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 241
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13259
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2828
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 4965
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23111
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 136
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 117
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 152
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 129
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 83
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31235
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3816
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 101
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Ala530Pro
num of homozygotes: 0
population: African
population: Other
population: European (Non-Finnish)
population: East Asian
population: South Asian
population: Latino
population: European (Finnish)
reference allele: G
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: VQSLOD
site quality: MQ
site quality: FS
site quality: BaseQRankSum
site quality: DP
site quality: QD

1-247588335-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588335
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588335
    reference: chr 1
allele count: 9
allele frequency: 7.441706631387466e-5
allele num: 120940
alternate allele: T
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1590C>T
  hgvsp: ENST00000366497.2:c.1590C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1590C>T
  hgvsp: ENST00000336119.3:c.1590C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1590C>T
  hgvsp: ENST00000391828.3:c.1590C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1765C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1590C>T
  hgvsp: ENST00000366496.2:c.1590C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1590C>T
  hgvsp: ENST00000348069.2:c.1590C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1590C>T
  hgvsp: ENST00000391827.2:c.1590C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 4974
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2827
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 237
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 28
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10867
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23115
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13284
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 364
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 192
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 51
  bin: 9.75e1
  variant carriers: 5
genotype quality: GenotypeQuality
  all individuals: 1153
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 99
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 148
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3798
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9986
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 20
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Ala530Ala
num of homozygotes: 0
population: South Asian
population: East Asian
population: Other
population: European (Finnish)
population: European (Non-Finnish)
population: African
population: Latino
reference allele: C
site quality: MQRankSum
site quality: FS
site quality: MQ
site quality: ReadPosRankSum
site quality: DP
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: QD

1-247588339-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588339
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588339
    reference: chr 1
allele count: 3
allele frequency: 2.48003571251426e-5
allele num: 120966
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1594A>G
  hgvsp: ENSP00000375703.2:p.Met532Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1594A>G
  hgvsp: ENSP00000375704.3:p.Met532Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1594A>G
  hgvsp: ENSP00000355452.2:p.Met532Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1769A>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1594A>G
  hgvsp: ENSP00000337383.3:p.Met532Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1594A>G
  hgvsp: ENSP00000355453.2:p.Met532Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1594A>G
  hgvsp: ENSP00000294752.3:p.Met532Val
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 10906
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 735
  bin: 5.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 23150
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 241
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 192
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4955
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 365
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2817
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13243
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 482
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1621
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 345
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 37
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 27
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 116
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2425
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3807
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 72
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 103
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Met532Val
num of homozygotes: 0
population: African
population: European (Finnish)
population: European (Non-Finnish)
population: East Asian
population: South Asian
population: Latino
population: Other
reference allele: A
site quality: QD
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: DP
site quality: InbreedingCoeff
site quality: FS
site quality: MQRankSum
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: MQ

1-247588351-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588351
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588351
    reference: chr 1
allele count: 191
allele frequency: 1.579243286148961e-3
allele num: 120944
alternate allele: T
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1606C>T
  hgvsp: ENST00000391827.2:c.1606C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1781C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1606C>T
  hgvsp: ENST00000348069.2:c.1606C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1606C>T
  hgvsp: ENST00000336119.3:c.1606C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1606C>T
  hgvsp: ENST00000366497.2:c.1606C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1606C>T
  hgvsp: ENST00000391828.3:c.1606C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: not_provided
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1606C>T
  hgvsp: ENST00000366496.2:c.1606C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 10929
  bin: 2.25e1
  variant carriers: 9
genotype depth: GenotypeDepth
  all individuals: 1634
  bin: 4.75e1
  variant carriers: 22
genotype depth: GenotypeDepth
  all individuals: 13238
  bin: 3.25e1
  variant carriers: 17
genotype depth: GenotypeDepth
  all individuals: 405
  bin: 1.75e1
  variant carriers: 7
genotype depth: GenotypeDepth
  all individuals: 739
  bin: 5.75e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 258
  bin: 1.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 4942
  bin: 3.75e1
  variant carriers: 13
genotype depth: GenotypeDepth
  all individuals: 23005
  bin: 2.75e1
  variant carriers: 14
genotype depth: GenotypeDepth
  all individuals: 59
  bin: 9.75e1
  variant carriers: 14
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2817
  bin: 4.25e1
  variant carriers: 18
genotype depth: GenotypeDepth
  all individuals: 1183
  bin: 5.25e1
  variant carriers: 25
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 347
  bin: 6.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 76
  bin: 8.25e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 183
  bin: 7.25e1
  variant carriers: 7
genotype quality: GenotypeQuality
  all individuals: 1146
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31192
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 18
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 139
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 136
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 68
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Leu536Leu
num of homozygotes: 2
population: European (Finnish)
population: African
population: South Asian
population: East Asian
population: Other
population: European (Non-Finnish)
population: Latino
reference allele: C
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: FS
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: MQRankSum
site quality: DP
site quality: ClippingRankSum
site quality: MQ
site quality: QD

1-247588374-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588374
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588374
    reference: chr 1
allele count: 15
allele frequency: 1.239710403649707e-4
allele num: 120996
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1629G>A
  hgvsp: ENST00000366497.2:c.1629G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1804G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1629G>A
  hgvsp: ENST00000366496.2:c.1629G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1629G>A
  hgvsp: ENST00000391827.2:c.1629G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1629G>A
  hgvsp: ENST00000391828.3:c.1629G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1629G>A
  hgvsp: ENST00000336119.3:c.1629G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1629G>A
  hgvsp: ENST00000348069.2:c.1629G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 22964
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1161
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1613
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10914
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13193
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 595
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2805
  bin: 4.25e1
  variant carriers: 7
genotype depth: GenotypeDepth
  all individuals: 189
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 310
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 347
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 4928
  bin: 3.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 357
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 182
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 222
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 228
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 141
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9897
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1388
  bin: 9.25e1
  variant carriers: 0
hgvs: p.Arg543Arg
num of homozygotes: 0
population: European (Finnish)
population: South Asian
population: East Asian
population: Latino
population: African
population: European (Non-Finnish)
population: Other
reference allele: G
site quality: MQRankSum
site quality: DP
site quality: MQ
site quality: InbreedingCoeff
site quality: QD
site quality: ClippingRankSum
site quality: FS
site quality: BaseQRankSum
site quality: VQSLOD
site quality: ReadPosRankSum

1-247588376-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588376
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588376
    reference: chr 1
allele count: 1
allele frequency: 8.266239026567692e-6
allele num: 120974
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1631C>T
  hgvsp: ENSP00000355453.2:p.Thr544Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1631C>T
  hgvsp: ENSP00000375703.2:p.Thr544Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1631C>T
  hgvsp: ENSP00000337383.3:p.Thr544Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1806C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1631C>T
  hgvsp: ENSP00000355452.2:p.Thr544Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1631C>T
  hgvsp: ENSP00000294752.3:p.Thr544Met
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1631C>T
  hgvsp: ENSP00000375704.3:p.Thr544Met
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1613
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 614
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 186
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4921
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2802
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13224
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22945
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 311
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10896
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1162
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 151
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 187
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 176
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3697
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 258
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 14
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3780
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1140
  bin: 8.75e1
  variant carriers: 0
hgvs: p.Thr544Met
num of homozygotes: 0
population: Other
population: East Asian
population: Latino
population: South Asian
population: African
population: European (Finnish)
population: European (Non-Finnish)
reference allele: C
site quality: DP
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: QD
site quality: MQRankSum
site quality: MQ
site quality: VQSLOD

1-247588377-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588377
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588377
    reference: chr 1
allele count: 1
allele frequency: 8.264736024331383e-6
allele num: 120996
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1632G>A
  hgvsp: ENST00000391827.2:c.1632G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1632G>A
  hgvsp: ENST00000366497.2:c.1632G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1632G>A
  hgvsp: ENST00000366496.2:c.1632G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1632G>A
  hgvsp: ENST00000348069.2:c.1632G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1807G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1632G>A
  hgvsp: ENST00000336119.3:c.1632G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1632G>A
  hgvsp: ENST00000391828.3:c.1632G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2801
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 9
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 311
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13198
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10889
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22953
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4934
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 636
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1161
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1612
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 255
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1141
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 16
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5729
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9900
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 356
  bin: 2.25e1
  variant carriers: 0
hgvs: p.Thr544Thr
num of homozygotes: 0
population: European (Finnish)
population: Other
population: Latino
population: East Asian
population: South Asian
population: African
population: European (Non-Finnish)
reference allele: G
site quality: ReadPosRankSum
site quality: DP
site quality: MQRankSum
site quality: FS
site quality: QD
site quality: MQ
site quality: VQSLOD
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: InbreedingCoeff

1-247588380-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588380
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588380
    reference: chr 1
allele count: 2
allele frequency: 1.652701340340787e-5
allele num: 121014
alternate allele: G
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1635C>G
  hgvsp: ENSP00000337383.3:p.Asn545Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1810C>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1635C>G
  hgvsp: ENSP00000355452.2:p.Asn545Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1635C>G
  hgvsp: ENSP00000375704.3:p.Asn545Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1635C>G
  hgvsp: ENSP00000375703.2:p.Asn545Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1635C>G
  hgvsp: ENSP00000294752.3:p.Asn545Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1635C>G
  hgvsp: ENSP00000355453.2:p.Asn545Lys
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10919
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22933
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 659
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1614
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 311
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 179
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13186
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 732
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4917
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2797
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1161
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 152
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1142
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 189
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 225
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1383
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 277
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 160
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Asn545Lys
num of homozygotes: 0
population: Other
population: European (Non-Finnish)
population: South Asian
population: African
population: European (Finnish)
population: East Asian
population: Latino
reference allele: C
site quality: ClippingRankSum
site quality: FS
site quality: QD
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: DP
site quality: BaseQRankSum
site quality: MQ
site quality: VQSLOD
site quality: InbreedingCoeff

1-247588380-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588380
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588380
    reference: chr 1
allele count: 4
allele frequency: 3.305402680681574e-5
allele num: 121014
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1635C>T
  hgvsp: ENST00000348069.2:c.1635C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1635C>T
  hgvsp: ENST00000336119.3:c.1635C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1635C>T
  hgvsp: ENST00000366497.2:c.1635C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1635C>T
  hgvsp: ENST00000391827.2:c.1635C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1635C>T
  hgvsp: ENST00000366496.2:c.1635C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1810C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1635C>T
  hgvsp: ENST00000391828.3:c.1635C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 311
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13186
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1161
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10919
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 732
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 659
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2797
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 179
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22933
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1614
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4917
  bin: 3.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 225
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1142
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3678
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 243
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 189
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 30848
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 201
  bin: 3.25e1
  variant carriers: 0
hgvs: p.Asn545Asn
num of homozygotes: 0
population: South Asian
population: African
population: European (Non-Finnish)
population: Other
population: Latino
population: European (Finnish)
population: East Asian
reference allele: C
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: DP
site quality: QD
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: MQ
site quality: BaseQRankSum

1-247588381-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588381
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588381
    reference: chr 1
allele count: 4
allele frequency: 3.305566574110803e-5
allele num: 121008
alternate allele: A
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1636G>A
  hgvsp: ENSP00000337383.3:p.Val546Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1811G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1636G>A
  hgvsp: ENSP00000375703.2:p.Val546Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1636G>A
  hgvsp: ENSP00000375704.3:p.Val546Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1636G>A
  hgvsp: ENSP00000355452.2:p.Val546Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1636G>A
  hgvsp: ENSP00000355453.2:p.Val546Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1636G>A
  hgvsp: ENSP00000294752.3:p.Val546Ile
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 708
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 172
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10883
  bin: 2.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 13189
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22903
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 319
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4926
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1159
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2803
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 732
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1614
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 479
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 14
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9878
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 222
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 196
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5727
  bin: 9.75e1
  variant carriers: 4
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 358
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 271
  bin: 4.75e1
  variant carriers: 0
hgvs: p.Val546Ile
num of homozygotes: 0
population: East Asian
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
population: Latino
population: African
population: Other
reference allele: G
site quality: DP
site quality: QD
site quality: FS
site quality: VQSLOD
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: MQ

1-247588390-A-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588390
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588390
    reference: chr 1
allele count: 45
allele frequency: 3.717287866772403e-4
allele num: 121056
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1645A>T
  hgvsp: ENSP00000355452.2:p.Ser549Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1645A>T
  hgvsp: ENSP00000337383.3:p.Ser549Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1645A>T
  hgvsp: ENSP00000375704.3:p.Ser549Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1645A>T
  hgvsp: ENSP00000375703.2:p.Ser549Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1820A>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1645A>T
  hgvsp: ENSP00000294752.3:p.Ser549Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1645A>T
  hgvsp: ENSP00000355453.2:p.Ser549Cys
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1612
  bin: 4.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 311
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13141
  bin: 3.25e1
  variant carriers: 9
genotype depth: GenotypeDepth
  all individuals: 1159
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4908
  bin: 3.75e1
  variant carriers: 7
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 6.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 22886
  bin: 2.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 774
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 350
  bin: 6.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2791
  bin: 4.25e1
  variant carriers: 8
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10925
  bin: 2.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 8.25e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 9899
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3689
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 348
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 207
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 290
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 30542
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Ser549Cys
num of homozygotes: 0
population: Other
population: Latino
population: African
population: East Asian
population: European (Finnish)
population: European (Non-Finnish)
population: South Asian
reference allele: A
site quality: QD
site quality: ReadPosRankSum
site quality: FS
site quality: VQSLOD
site quality: DP
site quality: MQ
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: BaseQRankSum

1-247588393-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588393
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588393
    reference: chr 1
allele count: 3
allele frequency: 2.477987213585978e-5
allele num: 121066
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1648C>T
  hgvsp: ENSP00000294752.3:p.Arg550Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1823C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1648C>T
  hgvsp: ENSP00000375703.2:p.Arg550Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1648C>T
  hgvsp: ENSP00000355453.2:p.Arg550Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1648C>T
  hgvsp: ENSP00000337383.3:p.Arg550Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1648C>T
  hgvsp: ENSP00000355452.2:p.Arg550Cys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1648C>T
  hgvsp: ENSP00000375704.3:p.Arg550Cys
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 22897
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 306
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13148
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 155
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10961
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1158
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1611
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4906
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 347
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2788
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 733
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 296
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9886
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 314
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 30675
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 209
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Arg550Cys
num of homozygotes: 0
population: South Asian
population: Other
population: European (Non-Finnish)
population: African
population: East Asian
population: Latino
population: European (Finnish)
reference allele: C
site quality: QD
site quality: InbreedingCoeff
site quality: FS
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: VQSLOD
site quality: MQRankSum
site quality: MQ
site quality: ClippingRankSum
site quality: DP

1-247588394-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588394
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588394
    reference: chr 1
allele count: 2
allele frequency: 1.652674026574998e-5
allele num: 121016
alternate allele: A
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1649G>A
  hgvsp: ENSP00000337383.3:p.Arg550His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1649G>A
  hgvsp: ENSP00000375704.3:p.Arg550His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1824G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1649G>A
  hgvsp: ENSP00000355452.2:p.Arg550His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1649G>A
  hgvsp: ENSP00000375703.2:p.Arg550His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1649G>A
  hgvsp: ENSP00000294752.3:p.Arg550His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1649G>A
  hgvsp: ENSP00000355453.2:p.Arg550His
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 348
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1161
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4943
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 152
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 477
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13170
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22896
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 301
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10892
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2806
  bin: 4.25e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 1374
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 337
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 214
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 13
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3646
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2393
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 30565
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 250
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 209
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Arg550His
num of homozygotes: 0
population: East Asian
population: African
population: Other
population: Latino
population: European (Non-Finnish)
population: South Asian
population: European (Finnish)
reference allele: G
site quality: FS
site quality: VQSLOD
site quality: MQ
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: MQRankSum
site quality: QD
site quality: DP

1-247588396-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588396
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588396
    reference: chr 1
allele count: 23
allele frequency: 1.899350917469074e-4
allele num: 121094
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1651T>C
  hgvsp: ENST00000366496.2:c.1651T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1651T>C
  hgvsp: ENST00000391828.3:c.1651T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1651T>C
  hgvsp: ENST00000366497.2:c.1651T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1826T>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1651T>C
  hgvsp: ENST00000391827.2:c.1651T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1651T>C
  hgvsp: ENST00000336119.3:c.1651T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1651T>C
  hgvsp: ENST00000348069.2:c.1651T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1615
  bin: 4.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 10985
  bin: 2.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13117
  bin: 3.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 348
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 151
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1160
  bin: 5.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 705
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 299
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2785
  bin: 4.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4889
  bin: 3.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 22969
  bin: 2.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9996
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1381
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 328
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5738
  bin: 9.75e1
  variant carriers: 23
genotype quality: GenotypeQuality
  all individuals: 3767
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 240
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 230
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2403
  bin: 8.25e1
  variant carriers: 0
hgvs: p.Leu551Leu
num of homozygotes: 0
population: African
population: East Asian
population: European (Non-Finnish)
population: South Asian
population: Other
population: Latino
population: European (Finnish)
reference allele: T
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: QD
site quality: ClippingRankSum
site quality: MQRankSum
site quality: DP
site quality: ReadPosRankSum
site quality: FS
site quality: BaseQRankSum
site quality: MQ

1-247588399-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588399
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588399
    reference: chr 1
allele count: 1
allele frequency: 8.258183860205463e-6
allele num: 121092
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1654A>G
  hgvsp: ENSP00000355452.2:p.Lys552Glu
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1654A>G
  hgvsp: ENSP00000375704.3:p.Lys552Glu
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1829A>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1654A>G
  hgvsp: ENSP00000375703.2:p.Lys552Glu
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1654A>G
  hgvsp: ENSP00000355453.2:p.Lys552Glu
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1654A>G
  hgvsp: ENSP00000337383.3:p.Lys552Glu
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1654A>G
  hgvsp: ENSP00000294752.3:p.Lys552Glu
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 10989
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 176
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 300
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 717
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1616
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 477
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13112
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2785
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22972
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 150
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1158
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4883
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 1135
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 253
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 264
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 187
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 155
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 230
  bin: 3.25e1
  variant carriers: 0
hgvs: p.Lys552Glu
num of homozygotes: 0
population: African
population: European (Finnish)
population: East Asian
population: Other
population: South Asian
population: European (Non-Finnish)
population: Latino
reference allele: A
site quality: FS
site quality: QD
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: MQ
site quality: DP

1-247588401-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588401
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588401
    reference: chr 1
allele count: 1
allele frequency: 8.258729477057249e-6
allele num: 121084
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1656G>A
  hgvsp: ENST00000348069.2:c.1656G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1656G>A
  hgvsp: ENST00000366496.2:c.1656G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1656G>A
  hgvsp: ENST00000366497.2:c.1656G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1656G>A
  hgvsp: ENST00000391828.3:c.1656G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1656G>A
  hgvsp: ENST00000336119.3:c.1656G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1656G>A
  hgvsp: ENST00000391827.2:c.1656G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1831G>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: VQSRTrancheSNP99.60to99.80
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 176
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 750
  bin: 1.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 731
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 147
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2788
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1616
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10930
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13130
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22983
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 299
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1158
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4881
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 346
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 478
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3654
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 191
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 167
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1137
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 234
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 308
  bin: 5.25e1
  variant carriers: 0
hgvs: p.Lys552Lys
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: East Asian
population: African
population: European (Non-Finnish)
population: Other
population: South Asian
reference allele: G
site quality: MQ
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: QD
site quality: BaseQRankSum
site quality: VQSLOD
site quality: DP
site quality: ClippingRankSum
site quality: FS
site quality: ReadPosRankSum

1-247588404-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588404
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588404
    reference: chr 1
allele count: 18
allele frequency: 1.504488390364588e-4
allele num: 119642
alternate allele: C
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1659T>C
  hgvsp: ENST00000336119.3:c.1659T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1659T>C
  hgvsp: ENST00000366496.2:c.1659T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1659T>C
  hgvsp: ENST00000391827.2:c.1659T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1659T>C
  hgvsp: ENST00000366497.2:c.1659T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1659T>C
  hgvsp: ENST00000348069.2:c.1659T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1659T>C
  hgvsp: ENST00000391828.3:c.1659T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1834T>C
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: VQSRTrancheSNP99.90to99.95
genotype depth: GenotypeDepth
  all individuals: 116
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 134
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 790
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1730
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22769
  bin: 2.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 2933
  bin: 4.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 745
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1240
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 198
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 293
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5051
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 50
  bin: 8.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10434
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 525
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 13144
  bin: 3.25e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 77
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 61
  bin: 9.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 381
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 33
  bin: 9.25e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 420
  bin: 2.5e0
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 430
  bin: 4.25e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 1056
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5429
  bin: 9.75e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 334
  bin: 2.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 735
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3529
  bin: 7.25e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 663
  bin: 5.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 648
  bin: 4.75e1
  variant carriers: 2
hgvs: p.Leu553Leu
num of homozygotes: 0
population: Latino
population: Other
population: European (Finnish)
population: African
population: East Asian
population: South Asian
population: European (Non-Finnish)
reference allele: T
site quality: MQ
site quality: MQRankSum
site quality: BaseQRankSum
site quality: FS
site quality: QD
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: DP

1-247588405-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588405
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588405
    reference: chr 1
allele count: 1
allele frequency: 8.255184255712587e-6
allele num: 121136
alternate allele: G
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1660C>G
  hgvsp: ENSP00000337383.3:p.Pro554Ala
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1660C>G
  hgvsp: ENSP00000375704.3:p.Pro554Ala
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1660C>G
  hgvsp: ENSP00000355452.2:p.Pro554Ala
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1660C>G
  hgvsp: ENSP00000294752.3:p.Pro554Ala
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1660C>G
  hgvsp: ENSP00000375703.2:p.Pro554Ala
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1660C>G
  hgvsp: ENSP00000355453.2:p.Pro554Ala
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1835C>G
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1163
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23348
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10363
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 128
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13433
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 632
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2784
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 748
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4898
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 486
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 257
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 73
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 105
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 107
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1122
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5683
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 215
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 191
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 290
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 259
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 218
  bin: 5.25e1
  variant carriers: 0
hgvs: p.Pro554Ala
num of homozygotes: 0
population: African
population: Other
population: East Asian
population: South Asian
population: European (Non-Finnish)
population: Latino
population: European (Finnish)
reference allele: C
site quality: FS
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: DP
site quality: QD

1-247588408-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588408
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588408
    reference: chr 1
allele count: 1
allele frequency: 8.254502831294471e-6
allele num: 121146
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1663A>G
  hgvsp: ENSP00000294752.3:p.Ser555Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1663A>G
  hgvsp: ENSP00000355453.2:p.Ser555Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1663A>G
  hgvsp: ENSP00000375704.3:p.Ser555Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1663A>G
  hgvsp: ENSP00000355452.2:p.Ser555Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1663A>G
  hgvsp: ENSP00000375703.2:p.Ser555Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1838A>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1663A>G
  hgvsp: ENSP00000337383.3:p.Ser555Gly
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: VQSRTrancheSNP99.60to99.80
genotype depth: GenotypeDepth
  all individuals: 124
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10399
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2783
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4890
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 242
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13461
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 579
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23366
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1165
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 105
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 146
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3670
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 199
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 97
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 176
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2415
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 223
  bin: 5.25e1
  variant carriers: 0
hgvs: p.Ser555Gly
num of homozygotes: 0
population: East Asian
population: European (Non-Finnish)
population: European (Finnish)
population: Latino
population: Other
population: African
population: South Asian
reference allele: A
site quality: FS
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: QD
site quality: ClippingRankSum
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: DP

1-247588410-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588410
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588410
    reference: chr 1
allele count: 2
allele frequency: 1.650737054094653e-5
allele num: 121158
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1665C>T
  hgvsp: ENST00000348069.2:c.1665C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1665C>T
  hgvsp: ENST00000391828.3:c.1665C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1840C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1665C>T
  hgvsp: ENST00000366497.2:c.1665C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1665C>T
  hgvsp: ENST00000366496.2:c.1665C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1665C>T
  hgvsp: ENST00000391827.2:c.1665C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1665C>T
  hgvsp: ENST00000336119.3:c.1665C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 240
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23372
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4892
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1165
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13476
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 569
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2784
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 123
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 105
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10388
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10065
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 112
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 143
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 167
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1119
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 131
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 254
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 207
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3745
  bin: 7.25e1
  variant carriers: 0
hgvs: p.Ser555Ser
num of homozygotes: 0
population: African
population: European (Non-Finnish)
population: South Asian
population: Latino
population: East Asian
population: European (Finnish)
population: Other
reference allele: C
site quality: FS
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: MQRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: QD
site quality: DP

1-247588416-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588416
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588416
    reference: chr 1
allele count: 8
allele frequency: 6.602403274792024e-5
allele num: 121168
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1671C>T
  hgvsp: ENST00000366497.2:c.1671C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1671C>T
  hgvsp: ENST00000348069.2:c.1671C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1671C>T
  hgvsp: ENST00000391827.2:c.1671C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1846C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1671C>T
  hgvsp: ENST00000366496.2:c.1671C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1671C>T
  hgvsp: ENST00000336119.3:c.1671C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1671C>T
  hgvsp: ENST00000391828.3:c.1671C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 10456
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1169
  bin: 5.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 489
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 116
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23432
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13474
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 4886
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 207
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2779
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31337
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 240
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1116
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3643
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 133
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 116
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 101
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Asp557Asp
num of homozygotes: 0
population: South Asian
population: Latino
population: East Asian
population: European (Finnish)
population: African
population: European (Non-Finnish)
population: Other
reference allele: C
site quality: DP
site quality: QD
site quality: MQ
site quality: MQRankSum
site quality: VQSLOD
site quality: FS
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum

1-247588421-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588421
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588421
    reference: chr 1
allele count: 1
allele frequency: 8.251369727374745e-6
allele num: 121192
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1676C>T
  hgvsp: ENSP00000337383.3:p.Thr559Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1851C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1676C>T
  hgvsp: ENSP00000355453.2:p.Thr559Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1676C>T
  hgvsp: ENSP00000375703.2:p.Thr559Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1676C>T
  hgvsp: ENSP00000355452.2:p.Thr559Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1676C>T
  hgvsp: ENSP00000375704.3:p.Thr559Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1676C>T
  hgvsp: ENSP00000294752.3:p.Thr559Ile
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23460
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 450
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13480
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 102
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10500
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4891
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2779
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1365
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 100
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 166
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 152
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 213
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31477
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 7.5e0
  variant carriers: 0
hgvs: p.Thr559Ile
num of homozygotes: 0
population: South Asian
population: European (Non-Finnish)
population: East Asian
population: African
population: Latino
population: European (Finnish)
population: Other
reference allele: C
site quality: QD
site quality: InbreedingCoeff
site quality: DP
site quality: ClippingRankSum
site quality: MQRankSum
site quality: MQ
site quality: VQSLOD
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: FS

1-247588423-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588423
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588423
    reference: chr 1
allele count: 1
allele frequency: 8.25082508250825e-6
allele num: 121200
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1678G>A
  hgvsp: ENSP00000375703.2:p.Val560Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1678G>A
  hgvsp: ENSP00000294752.3:p.Val560Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1678G>A
  hgvsp: ENSP00000337383.3:p.Val560Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1678G>A
  hgvsp: ENSP00000355453.2:p.Val560Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1678G>A
  hgvsp: ENSP00000355452.2:p.Val560Ile
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1853G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1678G>A
  hgvsp: ENSP00000375704.3:p.Val560Ile
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 10507
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 100
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 177
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 431
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4892
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23480
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13478
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2778
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3652
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 96
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 150
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 93
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1365
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10079
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Val560Ile
num of homozygotes: 0
population: Latino
population: Other
population: African
population: East Asian
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
reference allele: G
site quality: VQSLOD
site quality: BaseQRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: FS
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: MQ
site quality: QD

1-247588424-T-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588424
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588424
    reference: chr 1
allele count: 1
allele frequency: 8.250552787036732e-6
allele num: 121204
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1679T>A
  hgvsp: ENSP00000294752.3:p.Val560Asp
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1679T>A
  hgvsp: ENSP00000375703.2:p.Val560Asp
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1854T>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1679T>A
  hgvsp: ENSP00000355453.2:p.Val560Asp
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1679T>A
  hgvsp: ENSP00000375704.3:p.Val560Asp
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1679T>A
  hgvsp: ENSP00000337383.3:p.Val560Asp
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1679T>A
  hgvsp: ENSP00000355452.2:p.Val560Asp
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4887
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10523
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 98
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13467
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 175
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 419
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23499
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 117
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 79
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2418
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10099
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3654
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 202
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 89
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Val560Asp
num of homozygotes: 0
population: European (Non-Finnish)
population: European (Finnish)
population: Latino
population: East Asian
population: African
population: South Asian
population: Other
reference allele: T
site quality: ClippingRankSum
site quality: VQSLOD
site quality: QD
site quality: MQRankSum
site quality: MQ
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: DP

1-247588426-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588426
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588426
    reference: chr 1
allele count: 1
allele frequency: 8.249599894405122e-6
allele num: 121218
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1681C>T
  hgvsp: ENSP00000375703.2:p.Leu561Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1856C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1681C>T
  hgvsp: ENSP00000355452.2:p.Leu561Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1681C>T
  hgvsp: ENSP00000337383.3:p.Leu561Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1681C>T
  hgvsp: ENSP00000375704.3:p.Leu561Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1681C>T
  hgvsp: ENSP00000355453.2:p.Leu561Phe
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1681C>T
  hgvsp: ENSP00000294752.3:p.Leu561Phe
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2778
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13489
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 396
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23519
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 166
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1626
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 94
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10518
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4884
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 197
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 76
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3650
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 130
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 91
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10090
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 170
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 84
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Leu561Phe
num of homozygotes: 0
population: European (Finnish)
population: Other
population: European (Non-Finnish)
population: East Asian
population: Latino
population: South Asian
population: African
reference allele: C
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: ClippingRankSum
site quality: MQ
site quality: BaseQRankSum
site quality: DP
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: FS
site quality: QD

1-247588440-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588440
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588440
    reference: chr 1
allele count: 2
allele frequency: 1.649294102124291e-5
allele num: 121264
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1695T>C
  hgvsp: ENST00000348069.2:c.1695T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1695T>C
  hgvsp: ENST00000391828.3:c.1695T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1695T>C
  hgvsp: ENST00000366497.2:c.1695T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1695T>C
  hgvsp: ENST00000366496.2:c.1695T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1695T>C
  hgvsp: ENST00000391827.2:c.1695T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1695T>C
  hgvsp: ENST00000336119.3:c.1695T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1870T>C
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 117
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13505
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4888
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23689
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10590
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2775
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 205
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1367
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 67
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 98
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5683
  bin: 9.75e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 54
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 89
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Tyr565Tyr
num of homozygotes: 0
population: European (Finnish)
population: East Asian
population: African
population: South Asian
population: Latino
population: Other
population: European (Non-Finnish)
reference allele: T
site quality: MQ
site quality: QD
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: FS
site quality: DP
site quality: VQSLOD
site quality: ClippingRankSum

1-247588449-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588449
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588449
    reference: chr 1
allele count: 3
allele frequency: 2.473288484368817e-5
allele num: 121296
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1704C>T
  hgvsp: ENST00000366497.2:c.1704C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1704C>T
  hgvsp: ENST00000348069.2:c.1704C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1704C>T
  hgvsp: ENST00000336119.3:c.1704C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1704C>T
  hgvsp: ENST00000366496.2:c.1704C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1704C>T
  hgvsp: ENST00000391827.2:c.1704C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1704C>T
  hgvsp: ENST00000391828.3:c.1704C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1879C>T
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 13539
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10590
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4885
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 748
  bin: 5.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 58
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 108
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 80
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23808
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 40
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 105
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2423
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1368
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32119
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3766
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 35
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Phe568Phe
num of homozygotes: 0
population: Other
population: East Asian
population: South Asian
population: European (Non-Finnish)
population: African
population: Latino
population: European (Finnish)
reference allele: C
site quality: MQRankSum
site quality: MQ
site quality: FS
site quality: VQSLOD
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: DP
site quality: QD
site quality: ClippingRankSum
site quality: ReadPosRankSum

1-247588458-G-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588458
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588458
    reference: chr 1
allele count: 1
allele frequency: 8.24334350012365e-6
allele num: 121310
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1713G>T
  hgvsp: ENST00000391827.2:c.1713G>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1713G>T
  hgvsp: ENST00000348069.2:c.1713G>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1713G>T
  hgvsp: ENST00000391828.3:c.1713G>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1888G>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1713G>T
  hgvsp: ENST00000366497.2:c.1713G>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1713G>T
  hgvsp: ENST00000366496.2:c.1713G>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1713G>T
  hgvsp: ENST00000336119.3:c.1713G>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 60
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 51
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 61
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23870
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2772
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13548
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10592
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 179
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4888
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3781
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32227
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1121
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 27
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 22
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 19
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 22
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3674
  bin: 7.75e1
  variant carriers: 0
hgvs: p.Gly571Gly
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: Latino
population: African
population: Other
population: East Asian
population: South Asian
reference allele: G
site quality: MQRankSum
site quality: DP
site quality: VQSLOD
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: FS
site quality: MQ

1-247588485-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588485
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588485
    reference: chr 1
allele count: 1
allele frequency: 8.239268352970255e-6
allele num: 121370
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1740C>G
  hgvsp: ENST00000366496.2:c.1740C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1915C>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1740C>G
  hgvsp: ENST00000391828.3:c.1740C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1740C>G
  hgvsp: ENST00000366497.2:c.1740C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1740C>G
  hgvsp: ENST00000336119.3:c.1740C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1740C>G
  hgvsp: ENST00000348069.2:c.1740C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1740C>G
  hgvsp: ENST00000391827.2:c.1740C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4888
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23946
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1167
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 21
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 20
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13563
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 36
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 179
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10592
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32309
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3674
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2429
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3796
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1121
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10213
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Leu580Leu
num of homozygotes: 0
population: African
population: Other
population: East Asian
population: European (Finnish)
population: European (Non-Finnish)
population: South Asian
population: Latino
reference allele: C
site quality: FS
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: DP
site quality: MQ
site quality: InbreedingCoeff
site quality: QD
site quality: VQSLOD
site quality: ClippingRankSum
site quality: BaseQRankSum

1-247588487-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588487
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588487
    reference: chr 1
allele count: 1
allele frequency: 8.239132584121543e-6
allele num: 121372
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1742T>C
  hgvsp: ENSP00000294752.3:p.Phe581Ser
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1742T>C
  hgvsp: ENSP00000355453.2:p.Phe581Ser
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1742T>C
  hgvsp: ENSP00000375703.2:p.Phe581Ser
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1742T>C
  hgvsp: ENSP00000375704.3:p.Phe581Ser
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1742T>C
  hgvsp: ENSP00000355452.2:p.Phe581Ser
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1742T>C
  hgvsp: ENSP00000337383.3:p.Phe581Ser
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1917T>C
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2773
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10600
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 34
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23945
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 20
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 179
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13564
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4891
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2429
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3676
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10214
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32322
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
hgvs: p.Phe581Ser
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: Latino
population: African
population: Other
population: East Asian
population: South Asian
reference allele: T
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: FS
site quality: DP
site quality: QD
site quality: MQ
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: ClippingRankSum

1-247588492-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588492
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588492
    reference: chr 1
allele count: 1
allele frequency: 8.238589553468446e-6
allele num: 121380
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1747C>T
  hgvsp: ENST00000366496.2:c.1747C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1747C>T
  hgvsp: ENST00000348069.2:c.1747C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1747C>T
  hgvsp: ENST00000391828.3:c.1747C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1747C>T
  hgvsp: ENST00000336119.3:c.1747C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1747C>T
  hgvsp: ENST00000366497.2:c.1747C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1747C>T
  hgvsp: ENST00000391827.2:c.1747C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1922C>T
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 489
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 34
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23952
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 16
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10586
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13573
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 16
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4890
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32324
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5682
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3679
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 36
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Leu583Leu
num of homozygotes: 0
population: Latino
population: African
population: European (Finnish)
population: South Asian
population: East Asian
population: European (Non-Finnish)
population: Other
reference allele: C
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: FS
site quality: DP
site quality: MQ
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: VQSLOD
site quality: QD

1-247588509-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588509
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588509
    reference: chr 1
allele count: 2
allele frequency: 1.647636465490254e-5
allele num: 121386
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1764G>A
  hgvsp: ENST00000366496.2:c.1764G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1939G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1764G>A
  hgvsp: ENST00000391827.2:c.1764G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1764G>A
  hgvsp: ENST00000336119.3:c.1764G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1764G>A
  hgvsp: ENST00000348069.2:c.1764G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1764G>A
  hgvsp: ENST00000366497.2:c.1764G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1764G>A
  hgvsp: ENST00000391828.3:c.1764G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13584
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 23975
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 36
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2773
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10519
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4893
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 362
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3794
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10220
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 15
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1122
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3675
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
hgvs: p.Arg588Arg
num of homozygotes: 0
population: East Asian
population: European (Non-Finnish)
population: Latino
population: European (Finnish)
population: African
population: South Asian
population: Other
reference allele: G
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: FS
site quality: MQ
site quality: VQSLOD
site quality: QD
site quality: ClippingRankSum
site quality: MQRankSum
site quality: DP

1-247588515-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588515
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588515
    reference: chr 1
allele count: 1
allele frequency: 8.238182327451271e-6
allele num: 121386
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1770C>T
  hgvsp: ENST00000391827.2:c.1770C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1770C>T
  hgvsp: ENST00000348069.2:c.1770C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1770C>T
  hgvsp: ENST00000336119.3:c.1770C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1770C>T
  hgvsp: ENST00000366497.2:c.1770C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1945C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1770C>T
  hgvsp: ENST00000366496.2:c.1770C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1770C>T
  hgvsp: ENST00000391828.3:c.1770C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23969
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 59
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4892
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 39
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13588
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10510
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 19
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 27
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1373
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5682
  bin: 9.75e1
  variant carriers: 1
hgvs: p.Ser590Ser
num of homozygotes: 0
population: European (Non-Finnish)
population: Latino
population: East Asian
population: Other
population: South Asian
population: African
population: European (Finnish)
reference allele: C
site quality: MQRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: DP
site quality: BaseQRankSum
site quality: MQ
site quality: ClippingRankSum
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: QD

1-247588558-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588558
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588558
    reference: chr 1
allele count: 1
allele frequency: 8.238046594391538e-6
allele num: 121388
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1813A>G
  hgvsp: ENSP00000375703.2:p.Arg605Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1813A>G
  hgvsp: ENSP00000294752.3:p.Arg605Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1813A>G
  hgvsp: ENSP00000355452.2:p.Arg605Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1988A>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1813A>G
  hgvsp: ENSP00000337383.3:p.Arg605Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1813A>G
  hgvsp: ENSP00000355453.2:p.Arg605Gly
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1813A>G
  hgvsp: ENSP00000375704.3:p.Arg605Gly
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 11
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2772
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4894
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10427
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 93
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 63
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24000
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13579
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 44
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10204
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 23
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 56
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 39
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32157
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Arg605Gly
num of homozygotes: 0
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
population: Latino
population: Other
population: East Asian
population: African
reference allele: A
site quality: MQ
site quality: VQSLOD
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: FS
site quality: DP
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: QD

1-247588562-T-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588562
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588562
    reference: chr 1
allele count: 1
allele frequency: 8.238453806989504e-6
allele num: 121382
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1817T>A
  hgvsp: ENSP00000375703.2:p.Leu606Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1817T>A
  hgvsp: ENSP00000355452.2:p.Leu606Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1817T>A
  hgvsp: ENSP00000375704.3:p.Leu606Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1817T>A
  hgvsp: ENSP00000337383.3:p.Leu606Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1817T>A
  hgvsp: ENSP00000294752.3:p.Leu606Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1817T>A
  hgvsp: ENSP00000355453.2:p.Leu606Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1992T>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 69
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13575
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10427
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2773
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4885
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 113
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23984
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 28
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32071
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 48
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 37
  bin: 5.75e1
  variant carriers: 0
hgvs: p.Leu606Gln
num of homozygotes: 0
population: Other
population: European (Finnish)
population: East Asian
population: African
population: European (Non-Finnish)
population: South Asian
population: Latino
reference allele: T
site quality: QD
site quality: DP
site quality: InbreedingCoeff
site quality: MQ
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: BaseQRankSum
site quality: FS
site quality: ClippingRankSum
site quality: MQRankSum

1-247588565-A-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588565
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588565
    reference: chr 1
allele count: 2
allele frequency: 1.64766361299677e-5
allele num: 121384
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1820A>T
  hgvsp: ENSP00000337383.3:p.Glu607Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1820A>T
  hgvsp: ENSP00000355452.2:p.Glu607Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1820A>T
  hgvsp: ENSP00000294752.3:p.Glu607Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1820A>T
  hgvsp: ENSP00000355453.2:p.Glu607Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1995A>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1820A>T
  hgvsp: ENSP00000375704.3:p.Glu607Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1820A>T
  hgvsp: ENSP00000375703.2:p.Glu607Val
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 120
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 68
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4885
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10411
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1167
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23987
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13579
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 48
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2422
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3662
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Glu607Val
num of homozygotes: 0
population: Latino
population: African
population: East Asian
population: European (Finnish)
population: Other
population: European (Non-Finnish)
population: South Asian
reference allele: A
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: DP
site quality: VQSLOD
site quality: FS
site quality: MQRankSum
site quality: QD
site quality: ClippingRankSum
site quality: MQ

1-247588569-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588569
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588569
    reference: chr 1
allele count: 1
allele frequency: 8.238589553468446e-6
allele num: 121380
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1824G>A
  hgvsp: ENST00000391828.3:c.1824G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1824G>A
  hgvsp: ENST00000366497.2:c.1824G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1824G>A
  hgvsp: ENST00000366496.2:c.1824G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1824G>A
  hgvsp: ENST00000391827.2:c.1824G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1824G>A
  hgvsp: ENST00000336119.3:c.1824G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1824G>A
  hgvsp: ENST00000348069.2:c.1824G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.1999G>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 129
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10393
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 748
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1166
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13583
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23981
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4890
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 73
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 106
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2777
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3792
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 62
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 51
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3667
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 33
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Leu608Leu
num of homozygotes: 0
population: East Asian
population: Latino
population: African
population: Other
population: European (Non-Finnish)
population: European (Finnish)
population: South Asian
reference allele: G
site quality: DP
site quality: VQSLOD
site quality: MQ
site quality: QD
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: MQRankSum
site quality: FS

1-247588606-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588606
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588606
    reference: chr 1
allele count: 2
allele frequency: 1.647826516824309e-5
allele num: 121372
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1861C>T
  hgvsp: ENST00000391827.2:c.1861C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1861C>T
  hgvsp: ENST00000366497.2:c.1861C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1861C>T
  hgvsp: ENST00000391828.3:c.1861C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1861C>T
  hgvsp: ENST00000336119.3:c.1861C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1861C>T
  hgvsp: ENST00000348069.2:c.1861C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1861C>T
  hgvsp: ENST00000366496.2:c.1861C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2036C>T
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 4875
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10331
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23912
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 114
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13539
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 491
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2774
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1168
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 17
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 8.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 276
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 747
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1623
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5681
  bin: 9.75e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 84
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 63
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 94
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31772
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3768
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 82
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Leu621Leu
num of homozygotes: 0
population: East Asian
population: Latino
population: South Asian
population: European (Finnish)
population: African
population: Other
population: European (Non-Finnish)
reference allele: C
site quality: DP
site quality: FS
site quality: MQ
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: MQRankSum
site quality: ClippingRankSum
site quality: QD
site quality: VQSLOD

http://identifiers.org/exac.variant/1-247588609-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588609
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588609
    reference: chr 1
allele count: 1
allele frequency: 8.240354664864776e-6
allele num: 121354
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1864C>A
  hgvsp: ENSP00000375703.2:p.Gln622Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1864C>A
  hgvsp: ENSP00000337383.3:p.Gln622Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1864C>A
  hgvsp: ENSP00000375704.3:p.Gln622Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1864C>A
  hgvsp: ENSP00000355452.2:p.Gln622Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1864C>A
  hgvsp: ENSP00000294752.3:p.Gln622Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1864C>A
  hgvsp: ENSP00000355453.2:p.Gln622Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2039C>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: VQSRTrancheSNP99.60to99.80
genotype depth: GenotypeDepth
  all individuals: 108
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10314
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4883
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23896
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 746
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1171
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2779
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 117
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1624
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 292
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13538
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 490
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 115
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10115
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3648
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2405
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31537
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 102
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Gln622Lys
num of homozygotes: 0
population: Other
population: East Asian
population: European (Finnish)
population: European (Non-Finnish)
population: Latino
population: African
population: South Asian
reference allele: C
site quality: VQSLOD
site quality: BaseQRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: FS
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: ClippingRankSum
site quality: QD
site quality: MQ

1-247588617-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588617
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588617
    reference: chr 1
allele count: 0
allele frequency: 0.0e0
allele num: 120696
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2047G>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1872G>C
  hgvsp: ENSP00000375704.3:p.Gln624His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1872G>C
  hgvsp: ENSP00000294752.3:p.Gln624His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1872G>C
  hgvsp: ENSP00000375703.2:p.Gln624His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1872G>C
  hgvsp: ENSP00000355453.2:p.Gln624His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1872G>C
  hgvsp: ENSP00000355452.2:p.Gln624His
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1872G>C
  hgvsp: ENSP00000337383.3:p.Gln624His
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: VQSRTrancheSNP99.90to99.95
genotype depth: GenotypeDepth
  all individuals: 13509
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 72
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 108
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1657
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4915
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1191
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10266
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 102
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23837
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 772
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 17
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 275
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2802
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 45
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 184
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 377
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 505
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 141
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31290
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1088
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 183
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 206
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2345
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 35
  bin: 7.5e0
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 261
  bin: 5.25e1
  variant carriers: 0
hgvs: p.Gln624His
num of homozygotes: 0
population: African
population: East Asian
population: Other
population: European (Finnish)
population: European (Non-Finnish)
population: Latino
population: South Asian
reference allele: G
site quality: MQ
site quality: FS
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: BaseQRankSum
site quality: DP
site quality: ClippingRankSum
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: QD

1-247588620-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588620
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588620
    reference: chr 1
allele count: 2
allele frequency: 1.647826516824309e-5
allele num: 121372
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1875C>T
  hgvsp: ENST00000391827.2:c.1875C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1875C>T
  hgvsp: ENST00000348069.2:c.1875C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2050C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1875C>T
  hgvsp: ENST00000366497.2:c.1875C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1875C>T
  hgvsp: ENST00000391828.3:c.1875C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1875C>T
  hgvsp: ENST00000336119.3:c.1875C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1875C>T
  hgvsp: ENST00000366496.2:c.1875C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1159
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24066
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10192
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 16
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 753
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4934
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13601
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 489
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2792
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 162
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 28
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10189
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 41
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2432
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 38
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Pro625Pro
num of homozygotes: 0
population: South Asian
population: European (Non-Finnish)
population: Other
population: African
population: East Asian
population: Latino
population: European (Finnish)
reference allele: C
site quality: BaseQRankSum
site quality: FS
site quality: DP
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: QD

1-247588645-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588645
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588645
    reference: chr 1
allele count: 1
allele frequency: 8.239132584121543e-6
allele num: 121372
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1900T>C
  hgvsp: ENST00000366497.2:c.1900T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1900T>C
  hgvsp: ENST00000366496.2:c.1900T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1900T>C
  hgvsp: ENST00000391827.2:c.1900T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1900T>C
  hgvsp: ENST00000336119.3:c.1900T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1900T>C
  hgvsp: ENST00000391828.3:c.1900T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2075T>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1900T>C
  hgvsp: ENST00000348069.2:c.1900T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10181
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 67
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4926
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13610
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 212
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24035
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1158
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2789
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 130
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 44
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5766
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 100
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 71
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2431
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
hgvs: p.Leu634Leu
num of homozygotes: 0
population: Other
population: African
population: European (Finnish)
population: Latino
population: European (Non-Finnish)
population: East Asian
population: South Asian
reference allele: T
site quality: DP
site quality: FS
site quality: QD
site quality: MQRankSum
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: ClippingRankSum

1-247588650-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588650
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588650
    reference: chr 1
allele count: 3
allele frequency: 2.472065658063878e-5
allele num: 121356
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1905C>G
  hgvsp: ENSP00000294752.3:p.Tyr635Ter
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1905C>G
  hgvsp: ENSP00000375704.3:p.Tyr635Ter
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1905C>G
  hgvsp: ENSP00000355452.2:p.Tyr635Ter
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1905C>G
  hgvsp: ENSP00000375703.2:p.Tyr635Ter
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: stop_gained
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1905C>G
  hgvsp: ENSP00000337383.3:p.Tyr635Ter
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1905C>G
  hgvsp: ENSP00000355453.2:p.Tyr635Ter
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2080C>G
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: stop gained
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 489
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 67
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1634
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1160
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10169
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 217
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 19
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 28
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24009
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4928
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2797
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 108
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13619
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 752
  bin: 5.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 1117
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31695
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 125
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 58
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10145
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3743
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 90
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 63
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Tyr635Ter
num of homozygotes: 0
population: Latino
population: European (Finnish)
population: South Asian
population: East Asian
population: African
population: European (Non-Finnish)
population: Other
reference allele: C
site quality: InbreedingCoeff
site quality: DP
site quality: VQSLOD
site quality: MQRankSum
site quality: QD
site quality: MQ
site quality: BaseQRankSum
site quality: FS
site quality: ReadPosRankSum
site quality: ClippingRankSum

1-247588650-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588650
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588650
    reference: chr 1
allele count: 21
allele frequency: 1.730445960644715e-4
allele num: 121356
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1905C>T
  hgvsp: ENST00000336119.3:c.1905C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1905C>T
  hgvsp: ENST00000391827.2:c.1905C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1905C>T
  hgvsp: ENST00000391828.3:c.1905C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1905C>T
  hgvsp: ENST00000366497.2:c.1905C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1905C>T
  hgvsp: ENST00000366496.2:c.1905C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2080C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1905C>T
  hgvsp: ENST00000348069.2:c.1905C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 13619
  bin: 3.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 108
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 752
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 24009
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10169
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4928
  bin: 3.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 19
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 217
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 67
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 46
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2797
  bin: 4.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1634
  bin: 4.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 489
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1160
  bin: 5.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 28
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 68
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 45
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 154
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 58
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1401
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3695
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 90
  bin: 5.75e1
  variant carriers: 0
hgvs: p.Tyr635Tyr
num of homozygotes: 0
population: East Asian
population: Latino
population: Other
population: African
population: European (Finnish)
population: European (Non-Finnish)
population: South Asian
reference allele: C
site quality: FS
site quality: ReadPosRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: VQSLOD
site quality: MQRankSum
site quality: MQ
site quality: QD
site quality: ClippingRankSum

1-247588651-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588651
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588651
    reference: chr 1
allele count: 1
allele frequency: 8.239539904091756e-6
allele num: 121366
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1906G>C
  hgvsp: ENSP00000294752.3:p.Glu636Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1906G>C
  hgvsp: ENSP00000355453.2:p.Glu636Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2081G>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1906G>C
  hgvsp: ENSP00000375703.2:p.Glu636Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1906G>C
  hgvsp: ENSP00000355452.2:p.Glu636Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1906G>C
  hgvsp: ENSP00000337383.3:p.Glu636Gln
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1906G>C
  hgvsp: ENSP00000375704.3:p.Glu636Gln
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2792
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 19
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1628
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 489
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1158
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13604
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10171
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 227
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 69
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4926
  bin: 3.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 750
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24029
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 152
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5761
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 1117
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 66
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31696
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3697
  bin: 7.75e1
  variant carriers: 0
hgvs: p.Glu636Gln
num of homozygotes: 0
population: Latino
population: European (Finnish)
population: South Asian
population: African
population: European (Non-Finnish)
population: East Asian
population: Other
reference allele: G
site quality: BaseQRankSum
site quality: FS
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: QD
site quality: DP
site quality: VQSLOD
site quality: MQ
site quality: ClippingRankSum

1-247588659-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588659
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588659
    reference: chr 1
allele count: 1
allele frequency: 8.239268352970255e-6
allele num: 121370
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1914G>A
  hgvsp: ENST00000366497.2:c.1914G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1914G>A
  hgvsp: ENST00000348069.2:c.1914G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1914G>A
  hgvsp: ENST00000366496.2:c.1914G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1914G>A
  hgvsp: ENST00000391828.3:c.1914G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1914G>A
  hgvsp: ENST00000336119.3:c.1914G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2089G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1914G>A
  hgvsp: ENST00000391827.2:c.1914G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 218
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1157
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 69
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2786
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10177
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 750
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13607
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24042
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4923
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2430
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 54
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10154
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3706
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 59
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 59
  bin: 3.25e1
  variant carriers: 0
hgvs: p.Gln638Gln
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: African
population: South Asian
population: Other
population: East Asian
population: Latino
reference allele: G
site quality: BaseQRankSum
site quality: MQ
site quality: MQRankSum
site quality: FS
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: QD
site quality: DP
site quality: InbreedingCoeff
site quality: VQSLOD

1-247588665-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588665
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588665
    reference: chr 1
allele count: 1
allele frequency: 8.238996819747227e-6
allele num: 121374
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1920G>A
  hgvsp: ENST00000391827.2:c.1920G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1920G>A
  hgvsp: ENST00000366496.2:c.1920G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1920G>A
  hgvsp: ENST00000366497.2:c.1920G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1920G>A
  hgvsp: ENST00000348069.2:c.1920G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1920G>A
  hgvsp: ENST00000391828.3:c.1920G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1920G>A
  hgvsp: ENST00000336119.3:c.1920G>A(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2095G>A
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1156
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24037
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2788
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13603
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4916
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 73
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 750
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10151
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 253
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1631
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2433
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1401
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 78
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 57
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 78
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10156
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Glu640Glu
num of homozygotes: 0
population: East Asian
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: Latino
population: South Asian
population: Other
reference allele: G
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQ
site quality: DP
site quality: ClippingRankSum
site quality: FS
site quality: BaseQRankSum
site quality: QD

1-247588666-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588666
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588666
    reference: chr 1
allele count: 1
allele frequency: 8.238861059847087e-6
allele num: 121376
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1921G>A
  hgvsp: ENSP00000375703.2:p.Asp641Asn
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1921G>A
  hgvsp: ENSP00000355453.2:p.Asp641Asn
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1921G>A
  hgvsp: ENSP00000294752.3:p.Asp641Asn
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2096G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1921G>A
  hgvsp: ENSP00000337383.3:p.Asp641Asn
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1921G>A
  hgvsp: ENSP00000355452.2:p.Asp641Asn
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1921G>A
  hgvsp: ENSP00000375704.3:p.Asp641Asn
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 750
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2792
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 252
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24026
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1630
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 10165
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4918
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1156
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 49
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13599
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3741
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3703
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 64
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2432
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 38
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Asp641Asn
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: European (Non-Finnish)
population: African
population: South Asian
population: East Asian
population: Other
reference allele: G
site quality: ClippingRankSum
site quality: MQ
site quality: DP
site quality: QD
site quality: FS
site quality: MQRankSum
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: BaseQRankSum

1-247588671-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588671
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588671
    reference: chr 1
allele count: 87
allele frequency: 7.168163467084123e-4
allele num: 121370
alternate allele: T
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1926C>T
  hgvsp: ENST00000366497.2:c.1926C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1926C>T
  hgvsp: ENST00000391828.3:c.1926C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1926C>T
  hgvsp: ENST00000336119.3:c.1926C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1926C>T
  hgvsp: ENST00000366496.2:c.1926C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2101C>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1926C>T
  hgvsp: ENST00000391827.2:c.1926C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  clinical significance: benign
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1926C>T
  hgvsp: ENST00000348069.2:c.1926C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 13594
  bin: 3.25e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 184
  bin: 7.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 63
  bin: 9.75e1
  variant carriers: 14
genotype depth: GenotypeDepth
  all individuals: 1629
  bin: 4.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 494
  bin: 6.25e1
  variant carriers: 7
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10162
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2796
  bin: 4.25e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 4918
  bin: 3.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 758
  bin: 5.75e1
  variant carriers: 8
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 6.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1165
  bin: 5.25e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 15
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 51
  bin: 8.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 252
  bin: 1.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 23979
  bin: 2.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 78
  bin: 8.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3693
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 62
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 81
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 166
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31666
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Phe642Phe
num of homozygotes: 0
population: Latino
population: Other
population: European (Finnish)
population: East Asian
population: South Asian
population: European (Non-Finnish)
population: African
reference allele: C
site quality: InbreedingCoeff
site quality: MQ
site quality: VQSLOD
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: FS
site quality: ReadPosRankSum
site quality: QD
site quality: MQRankSum
site quality: DP

http://identifiers.org/exac.variant/1-247588678-A-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588678
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588678
    reference: chr 1
allele count: 1
allele frequency: 8.238861059847087e-6
allele num: 121376
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1933A>C
  hgvsp: ENST00000391827.2:c.1933A>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1933A>C
  hgvsp: ENST00000391828.3:c.1933A>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1933A>C
  hgvsp: ENST00000366497.2:c.1933A>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1933A>C
  hgvsp: ENST00000336119.3:c.1933A>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1933A>C
  hgvsp: ENST00000348069.2:c.1933A>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2108A>C
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1933A>C
  hgvsp: ENST00000366496.2:c.1933A>C(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1624
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24018
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 16
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 490
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4918
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 224
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 66
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2787
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10198
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13606
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1157
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 54
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 122
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 57
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31797
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 56
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10167
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3710
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2429
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 62
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3735
  bin: 7.25e1
  variant carriers: 0
hgvs: p.Arg645Arg
num of homozygotes: 0
population: East Asian
population: European (Finnish)
population: Latino
population: African
population: South Asian
population: European (Non-Finnish)
population: Other
reference allele: A
site quality: MQ
site quality: FS
site quality: BaseQRankSum
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: QD
site quality: DP
site quality: VQSLOD
site quality: ClippingRankSum

1-247588679-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588679
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588679
    reference: chr 1
allele count: 1
allele frequency: 8.239132584121543e-6
allele num: 121372
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1934G>A
  hgvsp: ENSP00000375704.3:p.Arg645Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2109G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1934G>A
  hgvsp: ENSP00000294752.3:p.Arg645Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1934G>A
  hgvsp: ENSP00000337383.3:p.Arg645Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1934G>A
  hgvsp: ENSP00000355452.2:p.Arg645Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1934G>A
  hgvsp: ENSP00000375703.2:p.Arg645Lys
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1934G>A
  hgvsp: ENSP00000355453.2:p.Arg645Lys
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 54
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24018
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 16
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10207
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 216
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 65
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2790
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 491
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1157
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4921
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1624
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13599
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 73
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5769
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 54
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1102
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 113
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10166
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Arg645Lys
num of homozygotes: 0
population: European (Finnish)
population: South Asian
population: East Asian
population: European (Non-Finnish)
population: Other
population: Latino
population: African
reference allele: G
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: FS
site quality: BaseQRankSum
site quality: DP
site quality: QD
site quality: ClippingRankSum
site quality: MQ

1-247588681-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588681
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588681
    reference: chr 1
allele count: 1
allele frequency: 8.239675686364985e-6
allele num: 121364
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1936G>A
  hgvsp: ENSP00000355453.2:p.Ala646Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1936G>A
  hgvsp: ENSP00000294752.3:p.Ala646Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1936G>A
  hgvsp: ENSP00000337383.3:p.Ala646Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2111G>A
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1936G>A
  hgvsp: ENSP00000355452.2:p.Ala646Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1936G>A
  hgvsp: ENSP00000375704.3:p.Ala646Thr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1936G>A
  hgvsp: ENSP00000375703.2:p.Ala646Thr
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 13613
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 54
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1155
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24018
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1624
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10202
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 211
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4920
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 66
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 490
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2789
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 62
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31846
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 59
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1404
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2437
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3707
  bin: 7.75e1
  variant carriers: 0
hgvs: p.Ala646Thr
num of homozygotes: 0
population: Other
population: European (Finnish)
population: East Asian
population: Latino
population: African
population: European (Non-Finnish)
population: South Asian
reference allele: G
site quality: MQ
site quality: FS
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: MQRankSum
site quality: ClippingRankSum
site quality: VQSLOD
site quality: DP
site quality: QD

1-247588684-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588684
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588684
    reference: chr 1
allele count: 1
allele frequency: 8.239268352970255e-6
allele num: 121370
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1939A>G
  hgvsp: ENSP00000294752.3:p.Met647Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1939A>G
  hgvsp: ENSP00000355452.2:p.Met647Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2114A>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1939A>G
  hgvsp: ENSP00000355453.2:p.Met647Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1939A>G
  hgvsp: ENSP00000337383.3:p.Met647Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1939A>G
  hgvsp: ENSP00000375704.3:p.Met647Val
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1939A>G
  hgvsp: ENSP00000375703.2:p.Met647Val
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2784
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 24025
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1624
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1155
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 17
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 490
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10227
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 61
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 54
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13614
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4919
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 189
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 26
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3740
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2440
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1100
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 94
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 48
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 52
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 53
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Met647Val
num of homozygotes: 0
population: Other
population: European (Finnish)
population: South Asian
population: Latino
population: East Asian
population: European (Non-Finnish)
population: African
reference allele: A
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: VQSLOD
site quality: DP
site quality: FS
site quality: BaseQRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: MQ

1-247588687-G-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588687
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588687
    reference: chr 1
allele count: 3
allele frequency: 2.471739775236463e-5
allele num: 121372
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1942G>T
  hgvsp: ENSP00000337383.3:p.Asp648Tyr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1942G>T
  hgvsp: ENSP00000375703.2:p.Asp648Tyr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1942G>T
  hgvsp: ENSP00000294752.3:p.Asp648Tyr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1942G>T
  hgvsp: ENSP00000375704.3:p.Asp648Tyr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2117G>T
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1942G>T
  hgvsp: ENSP00000355453.2:p.Asp648Tyr
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1942G>T
  hgvsp: ENSP00000355452.2:p.Asp648Tyr
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 57
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4912
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2788
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 490
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24016
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10227
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13636
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 54
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1625
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1155
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 17
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 74
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 48
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 84
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 56
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 56
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 29
  bin: 2.75e1
  variant carriers: 0
hgvs: p.Asp648Tyr
num of homozygotes: 0
population: Latino
population: European (Finnish)
population: East Asian
population: African
population: European (Non-Finnish)
population: Other
population: South Asian
reference allele: G
site quality: DP
site quality: QD
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: FS
site quality: MQ
site quality: MQRankSum
site quality: BaseQRankSum
site quality: VQSLOD

1-247588698-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 247588698
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 247588698
    reference: chr 1
allele count: 1
allele frequency: 8.239132584121543e-6
allele num: 121372
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355453
  ensembl transcript: ENST00000366497
  gene symbol: NLRP3
  hgvsc: ENST00000366497.2:c.1953C>G
  hgvsp: ENST00000366497.2:c.1953C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375704
  ensembl transcript: ENST00000391828
  gene symbol: NLRP3
  hgvsc: ENST00000391828.3:c.1953C>G
  hgvsp: ENST00000391828.3:c.1953C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000162711
  ensembl transcript: ENST00000474792
  gene symbol: NLRP3
  hgvsc: ENST00000474792.1:n.2128C>G
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000355452
  ensembl transcript: ENST00000366496
  gene symbol: NLRP3
  hgvsc: ENST00000366496.2:c.1953C>G
  hgvsp: ENST00000366496.2:c.1953C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000337383
  ensembl transcript: ENST00000336119
  gene symbol: NLRP3
  hgvsc: ENST00000336119.3:c.1953C>G
  hgvsp: ENST00000336119.3:c.1953C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000294752
  ensembl transcript: ENST00000348069
  gene symbol: NLRP3
  hgvsc: ENST00000348069.2:c.1953C>G
  hgvsp: ENST00000348069.2:c.1953C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000162711
  ensembl protein: ENSP00000375703
  ensembl transcript: ENST00000391827
  gene symbol: NLRP3
  hgvsc: ENST00000391827.2:c.1953C>G
  hgvsp: ENST00000391827.2:c.1953C>G(p.%3D)
  variant of: http://identifiers.org/hgnc/16400
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 47
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 107
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 54
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 182
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24043
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4911
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1156
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 751
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10222
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 491
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1627
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 359
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 53
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13660
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 141
  bin: 1.75e1
  variant carriers: 0
hgvs: p.Pro651Pro
num of homozygotes: 0
reference allele: C

GenotypeQuality
all individuals: 170
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 98
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 9914
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1285
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3933
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 6131
bin: 9.75e1
variant carriers: 350

GenotypeQuality
all individuals: 765
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 26148
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 596
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2484
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1199
bin: 8.75e1
variant carriers: 1

GenotypeQuality
all individuals: 1430
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 420
bin: 4.25e1
variant carriers: 0

Latino
type: Population
allele count: 27
allele frequency: 2.34456408475165e-3
allele num: 11516
num of homozygotes: 0

Other
type: Population
allele count: 3
allele frequency: 3.31858407079646e-3
allele num: 904
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 273
allele frequency: 4.151712391264675e-3
allele num: 65756
num of homozygotes: 2

African
type: Population
allele count: 8
allele frequency: 7.903576368306659e-4
allele num: 10122
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 42
allele frequency: 6.371359223300971e-3
allele num: 6592
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.071645415907711e-5
allele num: 16470
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8552
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: -5.7e-2

MQRankSum
type: SiteQuality
SIO_000300: 1.27e-1

FS
type: SiteQuality
SIO_000300: 1.088e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.1e-3

QD
type: SiteQuality
SIO_000300: 1.379e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 5.95e-1

DP
type: SiteQuality
SIO_000300: 1.848346e6

BaseQRankSum
type: SiteQuality
SIO_000300: -2.024e0

VQSLOD
type: SiteQuality
SIO_000300: 3.99e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

GenotypeQuality
all individuals: 6
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 2504
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 120
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 713
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 25397
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 138
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 58
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1443
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 453
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 702
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1208
bin: 8.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6592
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11510
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10094
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.071645415907711e-5
allele num: 16470
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8558
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 65734
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.841841e6

QD
type: SiteQuality
SIO_000300: 9.779999999999999e0

ClippingRankSum
type: SiteQuality
SIO_000300: -2.14e-1

FS
type: SiteQuality
SIO_000300: 7.22e-1

VQSLOD
type: SiteQuality
SIO_000300: 3.89e-1

MQRankSum
type: SiteQuality
SIO_000300: 5.78e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -5.111e0

MQ
type: SiteQuality
SIO_000300: 5.931e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.8e-3

ReadPosRankSum
type: SiteQuality
SIO_000300: -2.55e-1

GenotypeQuality
all individuals: 277
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 9
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 1429
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 52
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 80
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 812
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1183
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 26774
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 502
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3875
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 9795
bin: 6.75e1
variant carriers: 1

GenotypeQuality
all individuals: 578
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3824
bin: 7.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8542
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.910802775024777e-5
allele num: 10090
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 1
allele frequency: 1.517450682852807e-4
allele num: 6590
num of homozygotes: 0

Latino
type: Population
allele count: 2
allele frequency: 1.738828029907842e-4
allele num: 11502
num of homozygotes: 0

South Asian
type: Population
allele count: 3
allele frequency: 1.822378811809015e-4
allele num: 16462
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 33
allele frequency: 5.021302495435179e-4
allele num: 65720
num of homozygotes: 0

Other
type: Population
allele count: 1
allele frequency: 1.106194690265487e-3
allele num: 904
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.326e1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.58e-1

FS
type: SiteQuality
SIO_000300: 0.0e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -2.0e-4

MQRankSum
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.502e0

VQSLOD
type: SiteQuality
SIO_000300: 5.4e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 3.61e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

DP
type: SiteQuality
SIO_000300: 1.83799e6

GenotypeQuality
all individuals: 57
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1289
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 657
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 384
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 602
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1427
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 26853
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 397
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3836
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5802
bin: 9.75e1
variant carriers: 2

GenotypeQuality
all individuals: 9749
bin: 6.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8526
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 902
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11490
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16458
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10096
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.044325377496347e-5
allele num: 65696
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6590
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: 6.889999999999999e-1

MQRankSum
type: SiteQuality
SIO_000300: 1.03e0

QD
type: SiteQuality
SIO_000300: 1.135e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 5.09e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 6.820000000000001e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

BaseQRankSum
type: SiteQuality
SIO_000300: -9.96e-1

FS
type: SiteQuality
SIO_000300: 9.7e-1

DP
type: SiteQuality
SIO_000300: 1.836894e6

GenotypeQuality
all individuals: 55
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 165
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 368
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 407
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 411
bin: 5.25e1
variant carriers: 0

GenotypeQuality
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bin: 2.5e0
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GenotypeQuality
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bin: 8.75e1
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GenotypeQuality
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GenotypeQuality
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bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3720
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5790
bin: 9.75e1
variant carriers: 2

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6592
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11498
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10122
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 65880
num of homozygotes: 0

South Asian
type: Population
allele count: 2
allele frequency: 1.215066828675577e-4
allele num: 16460
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 902
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8528
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.75e0

MQ
type: SiteQuality
SIO_000300: 5.958e1

VQSLOD
type: SiteQuality
SIO_000300: 5.47e-1

QD
type: SiteQuality
SIO_000300: 1.173e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 5.0e-4

MQRankSum
type: SiteQuality
SIO_000300: 5.16e-1

FS
type: SiteQuality
SIO_000300: 3.76e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.43e0

DP
type: SiteQuality
SIO_000300: 1.84614e6

ClippingRankSum
type: SiteQuality
SIO_000300: -1.45e-1

GenotypeQuality
all individuals: 962
bin: 2.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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bin: 2.5e0
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 9.25e1
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GenotypeQuality
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bin: 9.75e1
variant carriers: 1

GenotypeQuality
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bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 276
bin: 4.25e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8528
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 902
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10122
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.517911353976928e-5
allele num: 65880
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11498
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16460
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6592
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: 1.43e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 5.0e-4

QD
type: SiteQuality
SIO_000300: 1.173e1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.45e-1

MQRankSum
type: SiteQuality
SIO_000300: 5.16e-1

DP
type: SiteQuality
SIO_000300: 1.84614e6

FS
type: SiteQuality
SIO_000300: 3.76e-1

VQSLOD
type: SiteQuality
SIO_000300: 5.47e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.75e0

MQ
type: SiteQuality
SIO_000300: 5.958e1

GenotypeQuality
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bin: 4.75e1
variant carriers: 0

GenotypeQuality
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bin: 5.75e1
variant carriers: 0

GenotypeQuality
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bin: 9.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 363
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GenotypeQuality
all individuals: 5786
bin: 9.75e1
variant carriers: 1

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6596
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16462
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 900
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10160
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8536
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11498
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.516806212838248e-5
allele num: 65928
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 6.0e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.8e-3

ClippingRankSum
type: SiteQuality
SIO_000300: 4.1e-2

MQRankSum
type: SiteQuality
SIO_000300: 1.47e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.054e0

DP
type: SiteQuality
SIO_000300: 1.85107e6

QD
type: SiteQuality
SIO_000300: 1.279e1

VQSLOD
type: SiteQuality
SIO_000300: 3.68e-1

FS
type: SiteQuality
SIO_000300: 3.172e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 8.9e-1

GenotypeQuality
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bin: 7.75e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 5791
bin: 9.75e1
variant carriers: 16

European (Non-Finnish)
type: Population
allele count: 14
allele frequency: 2.121790791427965e-4
allele num: 65982
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11502
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6596
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.8405825624877e-5
allele num: 10162
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8542
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.072382803011902e-5
allele num: 16468
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 898
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: 2.0e-1

DP
type: SiteQuality
SIO_000300: 1.855206e6

QD
type: SiteQuality
SIO_000300: 1.298e1

FS
type: SiteQuality
SIO_000300: 1.143e0

MQ
type: SiteQuality
SIO_000300: 5.969e1

BaseQRankSum
type: SiteQuality
SIO_000300: 8.48e-1

VQSLOD
type: SiteQuality
SIO_000300: 4.33e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.4e-3

ClippingRankSum
type: SiteQuality
SIO_000300: -2.69e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.06e-1

GenotypeQuality
all individuals: 45
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 706
bin: 2.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 9.75e1
variant carriers: 71

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 101
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variant carriers: 0

GenotypeQuality
all individuals: 1405
bin: 9.25e1
variant carriers: 0

African
type: Population
allele count: 4
allele frequency: 3.923107100823852e-4
allele num: 10196
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 1
allele frequency: 1.515151515151515e-4
allele num: 6600
num of homozygotes: 0

Latino
type: Population
allele count: 2
allele frequency: 1.738525730180807e-4
allele num: 11504
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8560
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 64
allele frequency: 9.689922480620155e-4
allele num: 66048
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16474
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 902
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.86094e6

BaseQRankSum
type: SiteQuality
SIO_000300: -2.053e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 6.28e-1

MQ
type: SiteQuality
SIO_000300: 5.972e1

FS
type: SiteQuality
SIO_000300: 0.0e0

ClippingRankSum
type: SiteQuality
SIO_000300: -1.56e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -4.0e-4

QD
type: SiteQuality
SIO_000300: 1.36e1

MQRankSum
type: SiteQuality
SIO_000300: 1.02e-1

VQSLOD
type: SiteQuality
SIO_000300: 5.99e0

GenotypeQuality
all individuals: 202
bin: 2.75e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 706
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variant carriers: 0

GenotypeQuality
all individuals: 5836
bin: 9.75e1
variant carriers: 1

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.514050387596899e-5
allele num: 66048
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10196
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 902
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16474
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6600
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11504
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8560
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.86094e6

QD
type: SiteQuality
SIO_000300: 1.36e1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.56e-1

MQRankSum
type: SiteQuality
SIO_000300: 1.02e-1

MQ
type: SiteQuality
SIO_000300: 5.972e1

InbreedingCoeff
type: SiteQuality
SIO_000300: -4.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 5.99e0

FS
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.053e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 6.28e-1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 1408
bin: 9.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66108
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16484
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11514
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10246
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6608
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

East Asian
type: Population
allele count: 1
allele frequency: 1.164958061509786e-4
allele num: 8584
num of homozygotes: 0

VQSLOD
type: SiteQuality
SIO_000300: 8.169999999999999e-1

FS
type: SiteQuality
SIO_000300: 0.0e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

ClippingRankSum
type: SiteQuality
SIO_000300: -7.55e-1

MQRankSum
type: SiteQuality
SIO_000300: -3.63e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -2.1e-2

DP
type: SiteQuality
SIO_000300: 1.8644e6

ReadPosRankSum
type: SiteQuality
SIO_000300: 7.55e-1

MQ
type: SiteQuality
SIO_000300: 5.936e1

QD
type: SiteQuality
SIO_000300: 1.155e1

GenotypeQuality
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bin: 7.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 15
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GenotypeQuality
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GenotypeQuality
all individuals: 7
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 1409
bin: 9.25e1
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GenotypeQuality
all individuals: 83
bin: 3.75e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10264
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.680555555555556e-5
allele num: 11520
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8598
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6608
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66132
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16490
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.45e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

FS
type: SiteQuality
SIO_000300: 0.0e0

MQRankSum
type: SiteQuality
SIO_000300: 4.55e-1

VQSLOD
type: SiteQuality
SIO_000300: 3.89e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.554e0

BaseQRankSum
type: SiteQuality
SIO_000300: -7.15e-1

MQ
type: SiteQuality
SIO_000300: 5.97e1

QD
type: SiteQuality
SIO_000300: 8.81e0

DP
type: SiteQuality
SIO_000300: 1.866053e6

GenotypeQuality
all individuals: 3836
bin: 7.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 9.75e1
variant carriers: 4

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 56
bin: 4.25e1
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GenotypeQuality
all individuals: 112
bin: 2.75e1
variant carriers: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16492
num of homozygotes: 0

East Asian
type: Population
allele count: 2
allele frequency: 2.325581395348837e-4
allele num: 8600
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10282
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11522
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6608
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.023340186237756e-5
allele num: 66152
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 1.53e0

DP
type: SiteQuality
SIO_000300: 1.86681e6

FS
type: SiteQuality
SIO_000300: 5.34e-1

MQRankSum
type: SiteQuality
SIO_000300: 6.66e-1

QD
type: SiteQuality
SIO_000300: 1.083e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.14e0

BaseQRankSum
type: SiteQuality
SIO_000300: 1.71e0

MQ
type: SiteQuality
SIO_000300: 5.941e1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.079e0

GenotypeQuality
all individuals: 2
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 47
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 10039
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variant carriers: 0

GenotypeQuality
all individuals: 29
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 41
bin: 7.5e0
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GenotypeQuality
all individuals: 71
bin: 2.75e1
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GenotypeQuality
all individuals: 3753
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3843
bin: 7.25e1
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GenotypeQuality
all individuals: 2430
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 46
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 318
bin: 2.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66272
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.682416731216112e-5
allele num: 10328
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11548
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8626
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16504
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 0.0e0

ClippingRankSum
type: SiteQuality
SIO_000300: 3.1e-2

DP
type: SiteQuality
SIO_000300: 1.870161e6

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

ReadPosRankSum
type: SiteQuality
SIO_000300: -4.62e-1

MQRankSum
type: SiteQuality
SIO_000300: 3.39e-1

QD
type: SiteQuality
SIO_000300: 1.093e1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.785e0

VQSLOD
type: SiteQuality
SIO_000300: -3.344e-1

MQ
type: SiteQuality
SIO_000300: 5.561e1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 4.75e1
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GenotypeQuality
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bin: 7.75e1
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GenotypeQuality
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bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 1160
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2429
bin: 8.25e1
variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66346
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.059871530723549e-5
allele num: 16502
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11556
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10346
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 2.772e0

MQRankSum
type: SiteQuality
SIO_000300: -8.4e-1

DP
type: SiteQuality
SIO_000300: 1.872104e6

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.5e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -4.5e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 3.04e-1

QD
type: SiteQuality
SIO_000300: 1.234e1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

MQ
type: SiteQuality
SIO_000300: 5.946e1

VQSLOD
type: SiteQuality
SIO_000300: 1.53e0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11558
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10346
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.05913717886573e-5
allele num: 16504
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66354
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.964e1

BaseQRankSum
type: SiteQuality
SIO_000300: -6.315e0

VQSLOD
type: SiteQuality
SIO_000300: 9.76e-1

FS
type: SiteQuality
SIO_000300: 1.582e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.47e0

DP
type: SiteQuality
SIO_000300: 1.871979e6

ClippingRankSum
type: SiteQuality
SIO_000300: -1.627e0

MQRankSum
type: SiteQuality
SIO_000300: 2.12e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

QD
type: SiteQuality
SIO_000300: 1.122e1

GenotypeQuality
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bin: 3.75e1
variant carriers: 0

GenotypeQuality
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bin: 7.5e0
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 31379
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GenotypeQuality
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variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8650
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10354
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.652015919709292e-5
allele num: 11558
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66372
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 1.076e0

BaseQRankSum
type: SiteQuality
SIO_000300: -9.27e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 1.48e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

ReadPosRankSum
type: SiteQuality
SIO_000300: -5.5e-2

VQSLOD
type: SiteQuality
SIO_000300: 9.370000000000001e-1

MQRankSum
type: SiteQuality
SIO_000300: 9.27e-1

QD
type: SiteQuality
SIO_000300: 8.99e0

DP
type: SiteQuality
SIO_000300: 1.871209e6

GenotypeQuality
all individuals: 1406
bin: 9.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 2435
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GenotypeQuality
all individuals: 292
bin: 2.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10350
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66374
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8648
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.05913717886573e-5
allele num: 16504
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11558
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: -1.274e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.27e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 6.6e-3

MQRankSum
type: SiteQuality
SIO_000300: -6.15e-1

VQSLOD
type: SiteQuality
SIO_000300: 3.94e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

FS
type: SiteQuality
SIO_000300: 4.288e0

BaseQRankSum
type: SiteQuality
SIO_000300: -1.186e0

DP
type: SiteQuality
SIO_000300: 1.870601e6

QD
type: SiteQuality
SIO_000300: 1.281e1

GenotypeQuality
all individuals: 93
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 287
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variant carriers: 0

GenotypeQuality
all individuals: 89
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 5770
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variant carriers: 9

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 3741
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GenotypeQuality
all individuals: 117
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variant carriers: 0

South Asian
type: Population
allele count: 8
allele frequency: 4.847309743092584e-4
allele num: 16504
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8648
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66368
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.66183574879227e-5
allele num: 10350
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11554
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: 5.92e-1

FS
type: SiteQuality
SIO_000300: 1.163e0

MQ
type: SiteQuality
SIO_000300: 5.962e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 8.35e-1

DP
type: SiteQuality
SIO_000300: 1.871807e6

BaseQRankSum
type: SiteQuality
SIO_000300: 2.02e0

ClippingRankSum
type: SiteQuality
SIO_000300: -8.31e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 4.6e-3

VQSLOD
type: SiteQuality
SIO_000300: 2.52e0

QD
type: SiteQuality
SIO_000300: 1.343e1

GenotypeQuality
all individuals: 14
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variant carriers: 0

GenotypeQuality
all individuals: 109
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 3

African
type: Population
allele count: 1
allele frequency: 9.659969088098918e-5
allele num: 10352
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.50652324565368e-5
allele num: 66378
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.652015919709292e-5
allele num: 11558
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.331e1

ReadPosRankSum
type: SiteQuality
SIO_000300: -4.8e-1

VQSLOD
type: SiteQuality
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DP
type: SiteQuality
SIO_000300: 1.870257e6

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

FS
type: SiteQuality
SIO_000300: 5.84e-1

MQRankSum
type: SiteQuality
SIO_000300: 8.110000000000001e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -4.3e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -9.1e-2

MQ
type: SiteQuality
SIO_000300: 5.938e1

GenotypeQuality
all individuals: 142
bin: 4.75e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 9.25e1
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GenotypeQuality
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bin: 9.75e1
variant carriers: 188

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

African
type: Population
allele count: 175
allele frequency: 1.690494590417311e-2
allele num: 10352
num of homozygotes: 2

South Asian
type: Population
allele count: 1
allele frequency: 6.05766900896535e-5
allele num: 16508
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8640
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 5
allele frequency: 7.5332971735069e-5
allele num: 66372
num of homozygotes: 0

Latino
type: Population
allele count: 10
allele frequency: 8.656509695290858e-4
allele num: 11552
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.87e-2

VQSLOD
type: SiteQuality
SIO_000300: 6.68e0

FS
type: SiteQuality
SIO_000300: 0.0e0

ReadPosRankSum
type: SiteQuality
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BaseQRankSum
type: SiteQuality
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MQRankSum
type: SiteQuality
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DP
type: SiteQuality
SIO_000300: 1.872845e6

ClippingRankSum
type: SiteQuality
SIO_000300: -2.06e-1

MQ
type: SiteQuality
SIO_000300: 5.976e1

QD
type: SiteQuality
SIO_000300: 1.341e1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
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Latino
type: Population
allele count: 15
allele frequency: 1.298476454293629e-3
allele num: 11552
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10358
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66424
num of homozygotes: 0

Other
type: Population
allele count: 0
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allele num: 906
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MQRankSum
type: SiteQuality
SIO_000300: 1.19e-1

DP
type: SiteQuality
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MQ
type: SiteQuality
SIO_000300: 6.0e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.5e-3

QD
type: SiteQuality
SIO_000300: 1.19e1

ClippingRankSum
type: SiteQuality
SIO_000300: -4.1e-2

FS
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
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SIO_000300: -2.639e0

VQSLOD
type: SiteQuality
SIO_000300: 4.19e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.12e-1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 197
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GenotypeQuality
all individuals: 2420
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GenotypeQuality
all individuals: 156
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GenotypeQuality
all individuals: 238
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variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16500
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African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10356
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

European (Non-Finnish)
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allele count: 1
allele frequency: 1.505661286437003e-5
allele num: 66416
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.866233e6

BaseQRankSum
type: SiteQuality
SIO_000300: -6.61e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 3.2e-3

FS
type: SiteQuality
SIO_000300: 0.0e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.62e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 2.53e0

QD
type: SiteQuality
SIO_000300: 1.206e1

MQRankSum
type: SiteQuality
SIO_000300: 1.1e0

MQ
type: SiteQuality
SIO_000300: 5.943e1

VQSLOD
type: SiteQuality
SIO_000300: 1.34e0

GenotypeQuality
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bin: 5.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 7.25e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11552
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16502
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10358
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.505343971097396e-5
allele num: 66430
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: 3.9e-2

DP
type: SiteQuality
SIO_000300: 1.865936e6

MQRankSum
type: SiteQuality
SIO_000300: 1.47e-1

FS
type: SiteQuality
SIO_000300: 4.372e0

QD
type: SiteQuality
SIO_000300: 1.17e1

MQ
type: SiteQuality
SIO_000300: 5.858e1

VQSLOD
type: SiteQuality
SIO_000300: -3.97e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -3.08e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -1.76e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.5e-3

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66434
num of homozygotes: 0

South Asian
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allele count: 2
allele frequency: 1.211680600993578e-4
allele num: 16506
num of homozygotes: 0

African
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allele count: 0
allele frequency: 0.0e0
allele num: 10362
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11556
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ClippingRankSum
type: SiteQuality
SIO_000300: -2.57e-1

FS
type: SiteQuality
SIO_000300: 6.217e0

QD
type: SiteQuality
SIO_000300: 1.274e1

MQRankSum
type: SiteQuality
SIO_000300: 9.79e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.69e-1

DP
type: SiteQuality
SIO_000300: 1.865759e6

BaseQRankSum
type: SiteQuality
SIO_000300: 1.25e0

MQ
type: SiteQuality
SIO_000300: 5.972e1

VQSLOD
type: SiteQuality
SIO_000300: 1.58e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.5e-3

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 4

GenotypeQuality
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bin: 8.25e1
variant carriers: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

African
type: Population
allele count: 3
allele frequency: 2.895193977996526e-4
allele num: 10362
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.505253334136135e-5
allele num: 66434
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11556
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: -2.57e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.5e-3

FS
type: SiteQuality
SIO_000300: 6.217e0

DP
type: SiteQuality
SIO_000300: 1.865759e6

QD
type: SiteQuality
SIO_000300: 1.274e1

VQSLOD
type: SiteQuality
SIO_000300: 1.58e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.69e-1

MQRankSum
type: SiteQuality
SIO_000300: 9.79e-1

MQ
type: SiteQuality
SIO_000300: 5.972e1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.25e0

GenotypeQuality
all individuals: 252
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 7.25e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8636
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.009962977455377e-5
allele num: 66446
num of homozygotes: 0

Latino
type: Population
allele count: 2
allele frequency: 1.731002250302925e-4
allele num: 11554
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10348
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.865407e6

QD
type: SiteQuality
SIO_000300: 1.329e1

FS
type: SiteQuality
SIO_000300: 7.497e0

VQSLOD
type: SiteQuality
SIO_000300: 1.44e0

BaseQRankSum
type: SiteQuality
SIO_000300: 2.51e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 8.110000000000001e-1

MQRankSum
type: SiteQuality
SIO_000300: -2.17e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -4.0e-4

ClippingRankSum
type: SiteQuality
SIO_000300: -5.99e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

GenotypeQuality
all individuals: 337
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variant carriers: 0

GenotypeQuality
all individuals: 8
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 184
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GenotypeQuality
all individuals: 1380
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variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

Latino
type: Population
allele count: 4
allele frequency: 3.460806367883717e-4
allele num: 11558
num of homozygotes: 0

African
type: Population
allele count: 40
allele frequency: 3.85951370127364e-3
allele num: 10364
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66476
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.05913717886573e-5
allele num: 16504
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.183e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 5.639999999999999e-1

FS
type: SiteQuality
SIO_000300: 0.0e0

VQSLOD
type: SiteQuality
SIO_000300: 5.73e0

DP
type: SiteQuality
SIO_000300: 1.865196e6

MQ
type: SiteQuality
SIO_000300: 5.975e1

ClippingRankSum
type: SiteQuality
SIO_000300: -2.68e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

MQRankSum
type: SiteQuality
SIO_000300: 1.82e-1

BaseQRankSum
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SIO_000300: -1.752e0

GenotypeQuality
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variant carriers: 3

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16504
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 3
allele frequency: 4.512092407652509e-5
allele num: 66488
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10366
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8634
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11556
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.03e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-3

FS
type: SiteQuality
SIO_000300: 1.697e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -8.999999999999999e-3

BaseQRankSum
type: SiteQuality
SIO_000300: -7.88e-1

VQSLOD
type: SiteQuality
SIO_000300: 1.57e0

MQRankSum
type: SiteQuality
SIO_000300: -2.26e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

ClippingRankSum
type: SiteQuality
SIO_000300: 7.29e-1

DP
type: SiteQuality
SIO_000300: 1.864666e6

GenotypeQuality
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variant carriers: 2

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8628
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11546
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.008876184744998e-5
allele num: 66470
num of homozygotes: 0

South Asian
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allele num: 16506
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6602
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FS
type: SiteQuality
SIO_000300: 1.0022e1

VQSLOD
type: SiteQuality
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MQ
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
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InbreedingCoeff
type: SiteQuality
SIO_000300: 9.0e-4

ClippingRankSum
type: SiteQuality
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BaseQRankSum
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MQRankSum
type: SiteQuality
SIO_000300: -3.93e-1

QD
type: SiteQuality
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DP
type: SiteQuality
SIO_000300: 1.866408e6

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

African
type: Population
allele count: 17
allele frequency: 1.640609920864698e-3
allele num: 10362
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 4
allele frequency: 6.013952369497234e-5
allele num: 66512
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.05913717886573e-5
allele num: 16504
num of homozygotes: 0

Other
type: Population
allele count: 0
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allele num: 906
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.650519031141868e-5
allele num: 11560
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 7.0e-4

VQSLOD
type: SiteQuality
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QD
type: SiteQuality
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ClippingRankSum
type: SiteQuality
SIO_000300: -6.12e-1

MQRankSum
type: SiteQuality
SIO_000300: 2.19e-1

DP
type: SiteQuality
SIO_000300: 1.865304e6

ReadPosRankSum
type: SiteQuality
SIO_000300: 6.57e-1

FS
type: SiteQuality
SIO_000300: 1.123e0

BaseQRankSum
type: SiteQuality
SIO_000300: 2.97e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 3780
bin: 7.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10366
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

East Asian
type: Population
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allele frequency: 0.0e0
allele num: 8636
num of homozygotes: 0

Other
type: Population
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South Asian
type: Population
allele count: 1
allele frequency: 6.059871530723549e-5
allele num: 16502
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66510
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 5.577e0

QD
type: SiteQuality
SIO_000300: 1.362e1

BaseQRankSum
type: SiteQuality
SIO_000300: 4.36e0

ClippingRankSum
type: SiteQuality
SIO_000300: -9.73e-1

MQRankSum
type: SiteQuality
SIO_000300: -3.54e-1

ReadPosRankSum
type: SiteQuality
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InbreedingCoeff
type: SiteQuality
SIO_000300: 1.6e-3

VQSLOD
type: SiteQuality
SIO_000300: 6.22e-1

MQ
type: SiteQuality
SIO_000300: 5.961e1

DP
type: SiteQuality
SIO_000300: 1.865046e6

GenotypeQuality
all individuals: 331
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2401
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 176
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3767
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 16
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 30667
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 269
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 9967
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1382
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5717
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 309
bin: 4.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6608
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11562
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.648784253184099e-5
allele num: 10364
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66506
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16500
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.79e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.7e-3

MQRankSum
type: SiteQuality
SIO_000300: 2.17e0

QD
type: SiteQuality
SIO_000300: 6.92e0

BaseQRankSum
type: SiteQuality
SIO_000300: -3.62e-1

VQSLOD
type: SiteQuality
SIO_000300: -3.154e0

DP
type: SiteQuality
SIO_000300: 1.864922e6

ClippingRankSum
type: SiteQuality
SIO_000300: 1.27e0

FS
type: SiteQuality
SIO_000300: 0.0e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -1.087e0

GenotypeQuality
all individuals: 505
bin: 3.75e1
variant carriers: 3

GenotypeQuality
all individuals: 85
bin: 7.5e0
variant carriers: 1

GenotypeQuality
all individuals: 150
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 29355
bin: 6.25e1
variant carriers: 1

GenotypeQuality
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bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2236
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3432
bin: 7.75e1
variant carriers: 1

GenotypeQuality
all individuals: 1297
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 108
bin: 1.25e1
variant carriers: 1

GenotypeQuality
all individuals: 9470
bin: 6.75e1
variant carriers: 1

GenotypeQuality
all individuals: 408
bin: 3.25e1
variant carriers: 2

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11464
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 878
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 3
allele frequency: 4.724409448818898e-4
allele num: 6350
num of homozygotes: 0

African
type: Population
allele count: 4
allele frequency: 3.952569169960474e-4
allele num: 10120
num of homozygotes: 0

East Asian
type: Population
allele count: 1
allele frequency: 1.166588894073728e-4
allele num: 8572
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16428
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 10
allele frequency: 1.519064256418046e-4
allele num: 65830
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.934e1

MQRankSum
type: SiteQuality
SIO_000300: 2.85e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.588e0

FS
type: SiteQuality
SIO_000300: 1.73456e2

QD
type: SiteQuality
SIO_000300: 3.9e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.1e-3

ClippingRankSum
type: SiteQuality
SIO_000300: 1.31e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -8.88e-1

VQSLOD
type: SiteQuality
SIO_000300: -1.382e2

DP
type: SiteQuality
SIO_000300: 1.884612e6

GenotypeQuality
all individuals: 4
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 134
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 6
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 1366
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 31039
bin: 6.25e1
variant carriers: 0

GenotypeQuality
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bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3752
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2415
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 156
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3673
bin: 7.75e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10380
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8636
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.05766900896535e-5
allele num: 16508
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66532
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11564
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 7.11e0

MQRankSum
type: SiteQuality
SIO_000300: -2.51e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 8.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 2.41e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 4.37e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.25e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.2e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

DP
type: SiteQuality
SIO_000300: 1.873491e6

QD
type: SiteQuality
SIO_000300: 9.65e0

GenotypeQuality
all individuals: 108
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 10075
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 246
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variant carriers: 0

GenotypeQuality
all individuals: 1365
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 10
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1118
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 265
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5684
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 3751
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 31152
bin: 6.25e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8636
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.502810255177181e-5
allele num: 66542
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11562
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10380
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 1.7776e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 8.0e-4

MQRankSum
type: SiteQuality
SIO_000300: 7.92e-1

QD
type: SiteQuality
SIO_000300: 1.473e1

ClippingRankSum
type: SiteQuality
SIO_000300: -2.09e-1

VQSLOD
type: SiteQuality
SIO_000300: -2.703e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -4.37e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.767e0

MQ
type: SiteQuality
SIO_000300: 5.915e1

DP
type: SiteQuality
SIO_000300: 1.874153e6

GenotypeQuality
all individuals: 5
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 31105
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 262
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 264
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 4
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variant carriers: 0

GenotypeQuality
all individuals: 1365
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3661
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 5685
bin: 9.75e1
variant carriers: 2

GenotypeQuality
all individuals: 2410
bin: 8.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10384
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.502674761074713e-5
allele num: 66548
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.64902266043937e-5
allele num: 11562
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 7.326e0

ClippingRankSum
type: SiteQuality
SIO_000300: -7.22e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -2.137e0

MQRankSum
type: SiteQuality
SIO_000300: 6.45e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 5.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 1.31e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.35e-1

QD
type: SiteQuality
SIO_000300: 1.096e1

DP
type: SiteQuality
SIO_000300: 1.874454e6

GenotypeQuality
all individuals: 165
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 159
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1363
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1
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variant carriers: 0

GenotypeQuality
all individuals: 7
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 187
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variant carriers: 0

GenotypeQuality
all individuals: 214
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3752
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2414
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 10064
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5688
bin: 9.75e1
variant carriers: 8

South Asian
type: Population
allele count: 2
allele frequency: 1.21153380179307e-4
allele num: 16508
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11564
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8634
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

African
type: Population
allele count: 2
allele frequency: 1.925669170036588e-4
allele num: 10386
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 4
allele frequency: 6.009976561091412e-5
allele num: 66556
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.875587e6

QD
type: SiteQuality
SIO_000300: 1.233e1

MQ
type: SiteQuality
SIO_000300: 6.0e1

MQRankSum
type: SiteQuality
SIO_000300: 2.45e-1

VQSLOD
type: SiteQuality
SIO_000300: 4.12e0

FS
type: SiteQuality
SIO_000300: 1.111e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.03e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: -3.0e-4

ClippingRankSum
type: SiteQuality
SIO_000300: 2.9e-2

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.56e-1

GenotypeQuality
all individuals: 3756
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 126
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3645
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5
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variant carriers: 0

GenotypeQuality
all individuals: 5681
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 10074
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1118
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 122
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2414
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 191
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 93
bin: 4.25e1
variant carriers: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16504
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66576
num of homozygotes: 0

East Asian
type: Population
allele count: 1
allele frequency: 1.157675387821255e-4
allele num: 8638
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10392
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11562
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.484e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 6.5e-3

DP
type: SiteQuality
SIO_000300: 1.87622e6

ClippingRankSum
type: SiteQuality
SIO_000300: 5.83e-1

MQRankSum
type: SiteQuality
SIO_000300: 1.12e0

MQ
type: SiteQuality
SIO_000300: 5.535e1

VQSLOD
type: SiteQuality
SIO_000300: -1.342e0

BaseQRankSum
type: SiteQuality
SIO_000300: -1.617e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -6.5e-1

FS
type: SiteQuality
SIO_000300: 3.463e0

GenotypeQuality
all individuals: 2415
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 189
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3757
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 167
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variant carriers: 0

GenotypeQuality
all individuals: 209
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variant carriers: 0

GenotypeQuality
all individuals: 118
bin: 3.25e1
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GenotypeQuality
all individuals: 31518
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 84
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5682
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 3
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1121
bin: 8.75e1
variant carriers: 0

Latino
type: Population
allele count: 1
allele frequency: 8.647526807333103e-5
allele num: 11564
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10392
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8636
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66580
num of homozygotes: 0

VQSLOD
type: SiteQuality
SIO_000300: -1.325e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.207e0

DP
type: SiteQuality
SIO_000300: 1.876525e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 6.4e-3

FS
type: SiteQuality
SIO_000300: 0.0e0

MQRankSum
type: SiteQuality
SIO_000300: -6.43e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.0e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -4.0e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

QD
type: SiteQuality
SIO_000300: 1.984e1

GenotypeQuality
all individuals: 31553
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1366
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2
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GenotypeQuality
all individuals: 135
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3760
bin: 7.25e1
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GenotypeQuality
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GenotypeQuality
all individuals: 75
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GenotypeQuality
all individuals: 181
bin: 4.75e1
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GenotypeQuality
all individuals: 1120
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 164
bin: 5.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.501997656883655e-5
allele num: 66578
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11566
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10394
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: 1.04e0

VQSLOD
type: SiteQuality
SIO_000300: -1.938e0

QD
type: SiteQuality
SIO_000300: 1.223e1

MQRankSum
type: SiteQuality
SIO_000300: 6.1e-2

MQ
type: SiteQuality
SIO_000300: 5.971e1

ReadPosRankSum
type: SiteQuality
SIO_000300: -1.769e0

BaseQRankSum
type: SiteQuality
SIO_000300: 5.05e-1

FS
type: SiteQuality
SIO_000300: 1.0998e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 7.0e-3

DP
type: SiteQuality
SIO_000300: 1.876494e6

GenotypeQuality
all individuals: 2
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 113
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 188
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3754
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 31574
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1367
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1118
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5681
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 2416
bin: 8.25e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Other
type: Population
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allele frequency: 0.0e0
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European (Non-Finnish)
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allele frequency: 1.501681883709755e-5
allele num: 66592
num of homozygotes: 0

East Asian
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allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

Latino
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allele frequency: 0.0e0
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num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 16510
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African
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allele frequency: 0.0e0
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ReadPosRankSum
type: SiteQuality
SIO_000300: 3.59e-1

MQRankSum
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ClippingRankSum
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MQ
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BaseQRankSum
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DP
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VQSLOD
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InbreedingCoeff
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FS
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QD
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

East Asian
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allele frequency: 2.314814814814815e-4
allele num: 8640
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African
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allele frequency: 0.0e0
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South Asian
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allele frequency: 0.0e0
allele num: 16510
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Latino
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allele frequency: 0.0e0
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Other
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66632
num of homozygotes: 0

MQ
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QD
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ReadPosRankSum
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BaseQRankSum
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InbreedingCoeff
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MQRankSum
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FS
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DP
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VQSLOD
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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Other
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allele frequency: 0.0e0
allele num: 906
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East Asian
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allele frequency: 1.156871818602499e-4
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South Asian
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allele frequency: 0.0e0
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European (Non-Finnish)
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allele frequency: 3.00048007681229e-5
allele num: 66656
num of homozygotes: 0

African
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allele frequency: 0.0e0
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Latino
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allele frequency: 0.0e0
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European (Finnish)
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allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

MQRankSum
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MQ
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FS
type: SiteQuality
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VQSLOD
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BaseQRankSum
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InbreedingCoeff
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DP
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SIO_000300: 1.882264e6

QD
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ClippingRankSum
type: SiteQuality
SIO_000300: -9.97e-1

ReadPosRankSum
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SIO_000300: 1.4e0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 1

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66668
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Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11570
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.619084263178146e-5
allele num: 10396
num of homozygotes: 0

Other
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allele frequency: 0.0e0
allele num: 906
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East Asian
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allele count: 0
allele frequency: 0.0e0
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South Asian
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allele frequency: 0.0e0
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MQRankSum
type: SiteQuality
SIO_000300: 1.0e-2

DP
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VQSLOD
type: SiteQuality
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ClippingRankSum
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BaseQRankSum
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
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QD
type: SiteQuality
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InbreedingCoeff
type: SiteQuality
SIO_000300: -1.0e-4

FS
type: SiteQuality
SIO_000300: 9.669e0

MQ
type: SiteQuality
SIO_000300: 5.877e1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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African
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allele count: 0
allele frequency: 0.0e0
allele num: 10398
num of homozygotes: 0

Other
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allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8652
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
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European (Non-Finnish)
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allele count: 1
allele frequency: 1.498935755613514e-5
allele num: 66714
num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 2.184e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.16e0

MQRankSum
type: SiteQuality
SIO_000300: 5.2e-2

DP
type: SiteQuality
SIO_000300: 1.884419e6

MQ
type: SiteQuality
SIO_000300: 5.968e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

QD
type: SiteQuality
SIO_000300: 1.047e1

VQSLOD
type: SiteQuality
SIO_000300: 4.33e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 7.21e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 6.76e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 1
allele frequency: 1.498890820792613e-5
allele num: 66716
num of homozygotes: 0

Latino
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allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

African
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Other
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East Asian
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South Asian
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VQSLOD
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InbreedingCoeff
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FS
type: SiteQuality
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DP
type: SiteQuality
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QD
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MQ
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BaseQRankSum
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ReadPosRankSum
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MQRankSum
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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Latino
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African
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allele frequency: 0.0e0
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European (Finnish)
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South Asian
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East Asian
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European (Non-Finnish)
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allele num: 66722
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Other
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ClippingRankSum
type: SiteQuality
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ReadPosRankSum
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MQRankSum
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FS
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DP
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MQ
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InbreedingCoeff
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BaseQRankSum
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VQSLOD
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QD
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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East Asian
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European (Non-Finnish)
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Latino
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allele num: 11574
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European (Finnish)
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African
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South Asian
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Other
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BaseQRankSum
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InbreedingCoeff
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ReadPosRankSum
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FS
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MQ
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VQSLOD
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QD
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ClippingRankSum
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MQRankSum
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DP
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Non-Finnish)
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Latino
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East Asian
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South Asian
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African
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European (Finnish)
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MQRankSum
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FS
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InbreedingCoeff
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DP
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BaseQRankSum
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MQ
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ClippingRankSum
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VQSLOD
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ReadPosRankSum
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QD
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Finnish)
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South Asian
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European (Non-Finnish)
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Latino
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Other
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East Asian
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African
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MQ
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VQSLOD
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BaseQRankSum
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InbreedingCoeff
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MQRankSum
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SIO_000300: 3.95e-1

FS
type: SiteQuality
SIO_000300: 2.984e0

DP
type: SiteQuality
SIO_000300: 1.884451e6

ClippingRankSum
type: SiteQuality
SIO_000300: -1.623e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.71e0

QD
type: SiteQuality
SIO_000300: 1.212e1

GenotypeQuality
all individuals: 1372
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3667
bin: 7.75e1
variant carriers: 0

GenotypeQuality
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bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1121
bin: 8.75e1
variant carriers: 0

GenotypeQuality
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bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 10211
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2421
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 70
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 3793
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5683
bin: 9.75e1
variant carriers: 1

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.619084263178146e-5
allele num: 10396
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66728
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16510
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.931e1

DP
type: SiteQuality
SIO_000300: 1.884062e6

InbreedingCoeff
type: SiteQuality
SIO_000300: -2.0e-4

MQ
type: SiteQuality
SIO_000300: 6.0e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 5.43e-1

VQSLOD
type: SiteQuality
SIO_000300: -8.550000000000001e-2

BaseQRankSum
type: SiteQuality
SIO_000300: 2.21e0

FS
type: SiteQuality
SIO_000300: 7.053e0

ClippingRankSum
type: SiteQuality
SIO_000300: 1.93e-1

MQRankSum
type: SiteQuality
SIO_000300: 5.7e-2

GenotypeQuality
all individuals: 3791
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 48
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 60
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variant carriers: 0

GenotypeQuality
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variant carriers: 2

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1372
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 35
bin: 5.75e1
variant carriers: 0

Latino
type: Population
allele count: 1
allele frequency: 8.638562543192812e-5
allele num: 11576
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10396
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66728
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.056935190793458e-5
allele num: 16510
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: -2.0e-4

ReadPosRankSum
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
type: SiteQuality
SIO_000300: -4.94e-1

DP
type: SiteQuality
SIO_000300: 1.884371e6

VQSLOD
type: SiteQuality
SIO_000300: 6.55e-1

FS
type: SiteQuality
SIO_000300: 2.868e0

MQRankSum
type: SiteQuality
SIO_000300: 1.32e0

QD
type: SiteQuality
SIO_000300: 1.255e1

ClippingRankSum
type: SiteQuality
SIO_000300: 5.629999999999999e-1

MQ
type: SiteQuality
SIO_000300: 5.967e1

GenotypeQuality
all individuals: 40
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 10205
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 2418
bin: 8.25e1
variant carriers: 0

GenotypeQuality
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bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 45
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5684
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variant carriers: 1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 1120
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variant carriers: 0

GenotypeQuality
all individuals: 32071
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 61
bin: 4.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11578
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10396
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66724
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.05766900896535e-5
allele num: 16508
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.884135e6

VQSLOD
type: SiteQuality
SIO_000300: 4.63e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

QD
type: SiteQuality
SIO_000300: 1.413e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.81e-2

ClippingRankSum
type: SiteQuality
SIO_000300: -6.63e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 9.02e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.178e0

MQRankSum
type: SiteQuality
SIO_000300: 1.83e0

FS
type: SiteQuality
SIO_000300: 8.78e-1

GenotypeQuality
all individuals: 121
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 99
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 127
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1372
bin: 9.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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bin: 8.75e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 2407
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variant carriers: 0

GenotypeQuality
all individuals: 10150
bin: 6.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16510
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

African
type: Population
allele count: 2
allele frequency: 1.923076923076923e-4
allele num: 10400
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66716
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.881975e6

FS
type: SiteQuality
SIO_000300: 6.2e-1

MQ
type: SiteQuality
SIO_000300: 5.977e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.2e-3

ReadPosRankSum
type: SiteQuality
SIO_000300: 5.85e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -1.322e0

MQRankSum
type: SiteQuality
SIO_000300: 6.0e-3

ClippingRankSum
type: SiteQuality
SIO_000300: 8.27e-1

QD
type: SiteQuality
SIO_000300: 1.259e1

VQSLOD
type: SiteQuality
SIO_000300: 2.7e0

GenotypeQuality
all individuals: 3
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 206
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 182
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1371
bin: 9.25e1
variant carriers: 0

GenotypeQuality
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bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 86
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variant carriers: 0

GenotypeQuality
all individuals: 118
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5678
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 146
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1123
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3761
bin: 7.25e1
variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.49902563333833e-5
allele num: 66710
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11568
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10400
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

VQSLOD
type: SiteQuality
SIO_000300: -2.802e0

BaseQRankSum
type: SiteQuality
SIO_000300: -3.51e0

DP
type: SiteQuality
SIO_000300: 1.8819e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.4e-3

FS
type: SiteQuality
SIO_000300: 1.1968e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.5e0

MQRankSum
type: SiteQuality
SIO_000300: 3.17e0

ClippingRankSum
type: SiteQuality
SIO_000300: -1.928e0

QD
type: SiteQuality
SIO_000300: 1.582e1

MQ
type: SiteQuality
SIO_000300: 6.0e1

GenotypeQuality
all individuals: 3669
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 158
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5561
bin: 9.75e1
variant carriers: 0

GenotypeQuality
all individuals: 133
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 265
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variant carriers: 0

GenotypeQuality
all individuals: 9971
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variant carriers: 0

GenotypeQuality
all individuals: 137
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 55
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3603
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1347
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 211
bin: 5.75e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10316
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 890
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6370
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66428
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11554
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16500
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.913e1

FS
type: SiteQuality
SIO_000300: 1.03646e2

ReadPosRankSum
type: SiteQuality
SIO_000300: -8.99e-1

MQRankSum
type: SiteQuality
SIO_000300: 4.42e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.13e0

DP
type: SiteQuality
SIO_000300: 1.886488e6

ClippingRankSum
type: SiteQuality
SIO_000300: 1.14e0

VQSLOD
type: SiteQuality
SIO_000300: -5.048e1

InbreedingCoeff
type: SiteQuality
SIO_000300: -1.1e-3

QD
type: SiteQuality
SIO_000300: 3.5e-1

GenotypeQuality
all individuals: 0
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3766
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5765
bin: 9.75e1
variant carriers: 2

GenotypeQuality
all individuals: 31909
bin: 6.25e1
variant carriers: 0

GenotypeQuality
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bin: 5.25e1
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GenotypeQuality
all individuals: 1118
bin: 8.75e1
variant carriers: 0

GenotypeQuality
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bin: 4.75e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 61
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1399
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variant carriers: 0

GenotypeQuality
all individuals: 3706
bin: 7.75e1
variant carriers: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16510
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66714
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10404
num of homozygotes: 0

East Asian
type: Population
allele count: 2
allele frequency: 2.311604253351826e-4
allele num: 8652
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: 1.0e0

FS
type: SiteQuality
SIO_000300: 0.0e0

DP
type: SiteQuality
SIO_000300: 1.885907e6

VQSLOD
type: SiteQuality
SIO_000300: -7.624e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.62e0

MQRankSum
type: SiteQuality
SIO_000300: 1.72e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.8e-3

ClippingRankSum
type: SiteQuality
SIO_000300: -7.98e-1

QD
type: SiteQuality
SIO_000300: 1.234e1

GenotypeQuality
all individuals: 31761
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 39
bin: 2.75e1
variant carriers: 0

GenotypeQuality
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bin: 3.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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bin: 8.75e1
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GenotypeQuality
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bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 77
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 10184
bin: 6.75e1
variant carriers: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10404
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.498845888665727e-5
allele num: 66718
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.885208e6

FS
type: SiteQuality
SIO_000300: 2.621e0

QD
type: SiteQuality
SIO_000300: 1.344e1

MQRankSum
type: SiteQuality
SIO_000300: 1.38e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 3.16e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.82e0

MQ
type: SiteQuality
SIO_000300: 5.873e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.8e-3

VQSLOD
type: SiteQuality
SIO_000300: -7.985e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.458e0

GenotypeQuality
all individuals: 154
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2429
bin: 8.25e1
variant carriers: 0

GenotypeQuality
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bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2
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GenotypeQuality
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GenotypeQuality
all individuals: 5779
bin: 9.75e1
variant carriers: 3

GenotypeQuality
all individuals: 4
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 68
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 88
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variant carriers: 0

GenotypeQuality
all individuals: 1401
bin: 9.25e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 3
allele frequency: 4.535833081342606e-4
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8650
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10400
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66708
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 3.7e-3

DP
type: SiteQuality
SIO_000300: 1.885832e6

VQSLOD
type: SiteQuality
SIO_000300: 4.03e0

MQRankSum
type: SiteQuality
SIO_000300: 1.9e-1

QD
type: SiteQuality
SIO_000300: 1.337e1

MQ
type: SiteQuality
SIO_000300: 5.963e1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.93e0

FS
type: SiteQuality
SIO_000300: 1.745e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.37e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -2.04e-1

GenotypeQuality
all individuals: 63
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2429
bin: 8.25e1
variant carriers: 0

GenotypeQuality
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bin: 7.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
all individuals: 125
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 88
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5779
bin: 9.75e1
variant carriers: 21

GenotypeQuality
all individuals: 31695
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 10145
bin: 6.75e1
variant carriers: 0

GenotypeQuality
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bin: 8.75e1
variant carriers: 0

East Asian
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allele frequency: 0.0e0
allele num: 8650
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

Other
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allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

African
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allele count: 0
allele frequency: 0.0e0
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European (Finnish)
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allele count: 2
allele frequency: 3.023888720895071e-4
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 19
allele frequency: 2.848234094861186e-4
allele num: 66708
num of homozygotes: 0

South Asian
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allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

FS
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ReadPosRankSum
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DP
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InbreedingCoeff
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BaseQRankSum
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VQSLOD
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MQRankSum
type: SiteQuality
SIO_000300: 1.9e-1

MQ
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SIO_000300: 5.963e1

QD
type: SiteQuality
SIO_000300: 1.337e1

ClippingRankSum
type: SiteQuality
SIO_000300: -2.04e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 7.25e1
variant carriers: 0

Latino
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allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

European (Finnish)
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allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
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allele frequency: 6.05913717886573e-5
allele num: 16504
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African
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allele frequency: 0.0e0
allele num: 10404
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European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66714
num of homozygotes: 0

East Asian
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allele frequency: 0.0e0
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Other
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allele frequency: 0.0e0
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BaseQRankSum
type: SiteQuality
SIO_000300: 2.04e0

FS
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ReadPosRankSum
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MQRankSum
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InbreedingCoeff
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SIO_000300: 6.0e-3

QD
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DP
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VQSLOD
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MQ
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66716
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African
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South Asian
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Other
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allele frequency: 0.0e0
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num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

Latino
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allele frequency: 8.641548565502938e-5
allele num: 11572
num of homozygotes: 0

BaseQRankSum
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SIO_000300: -2.071e0

MQ
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MQRankSum
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FS
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ReadPosRankSum
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ClippingRankSum
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QD
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DP
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InbreedingCoeff
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SIO_000300: -3.0e-4

VQSLOD
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

European (Non-Finnish)
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allele count: 1
allele frequency: 1.498800959232614e-5
allele num: 66720
num of homozygotes: 0

African
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allele count: 0
allele frequency: 0.0e0
allele num: 10404
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

South Asian
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allele frequency: 0.0e0
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num of homozygotes: 0

Other
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

InbreedingCoeff
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MQRankSum
type: SiteQuality
SIO_000300: 8.110000000000001e-1

VQSLOD
type: SiteQuality
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ReadPosRankSum
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MQ
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SIO_000300: 5.963e1

DP
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ClippingRankSum
type: SiteQuality
SIO_000300: -1.95e-1

FS
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
type: SiteQuality
SIO_000300: -5.639999999999999e-1

QD
type: SiteQuality
SIO_000300: 9.359999999999999e0

GenotypeQuality
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variant carriers: 1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 8.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.498845888665727e-5
allele num: 66718
num of homozygotes: 0

African
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allele count: 0
allele frequency: 0.0e0
allele num: 10404
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South Asian
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allele count: 0
allele frequency: 0.0e0
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East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

ClippingRankSum
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MQ
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DP
type: SiteQuality
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QD
type: SiteQuality
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FS
type: SiteQuality
SIO_000300: 4.441e0

MQRankSum
type: SiteQuality
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VQSLOD
type: SiteQuality
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InbreedingCoeff
type: SiteQuality
SIO_000300: -2.0e-4

ReadPosRankSum
type: SiteQuality
SIO_000300: 6.78e-1

BaseQRankSum
type: SiteQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 87

GenotypeQuality
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variant carriers: 0

Latino
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allele count: 3
allele frequency: 2.592912705272256e-4
allele num: 11570
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

East Asian
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allele frequency: 3.466605038132656e-4
allele num: 8654
num of homozygotes: 0

South Asian
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allele frequency: 0.0e0
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num of homozygotes: 0

European (Non-Finnish)
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allele count: 1
allele frequency: 1.498890820792613e-5
allele num: 66716
num of homozygotes: 0

African
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allele count: 80
allele frequency: 7.689350249903883e-3
allele num: 10404
num of homozygotes: 0

InbreedingCoeff
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MQ
type: SiteQuality
SIO_000300: 5.974e1

VQSLOD
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ClippingRankSum
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BaseQRankSum
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FS
type: SiteQuality
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ReadPosRankSum
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QD
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MQRankSum
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DP
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

East Asian
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allele frequency: 1.155535012710885e-4
allele num: 8654
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11568
num of homozygotes: 0

African
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
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Other
type: Population
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allele frequency: 0.0e0
allele num: 906
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MQ
type: SiteQuality
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FS
type: SiteQuality
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BaseQRankSum
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SIO_000300: -4.05e-1

MQRankSum
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InbreedingCoeff
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
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QD
type: SiteQuality
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DP
type: SiteQuality
SIO_000300: 1.885708e6

VQSLOD
type: SiteQuality
SIO_000300: 1.63e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 1.35e0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 16508
num of homozygotes: 0

East Asian
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allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66720
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

African
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allele frequency: 9.613535858488752e-5
allele num: 10402
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InbreedingCoeff
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VQSLOD
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ReadPosRankSum
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MQRankSum
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FS
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BaseQRankSum
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DP
type: SiteQuality
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QD
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ClippingRankSum
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MQ
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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Other
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allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
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East Asian
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allele num: 8654
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Latino
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African
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European (Non-Finnish)
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South Asian
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MQ
type: SiteQuality
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FS
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ReadPosRankSum
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InbreedingCoeff
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BaseQRankSum
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MQRankSum
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ClippingRankSum
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VQSLOD
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DP
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QD
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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num of homozygotes: 0

European (Finnish)
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allele frequency: 0.0e0
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South Asian
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Latino
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allele frequency: 8.646031471554557e-5
allele num: 11566
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East Asian
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European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66724
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African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10402
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: -1.87e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.27e0

MQRankSum
type: SiteQuality
SIO_000300: 1.06e0

VQSLOD
type: SiteQuality
SIO_000300: 1.32e-1

DP
type: SiteQuality
SIO_000300: 1.885997e6

FS
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
type: SiteQuality
SIO_000300: -5.31e-1

QD
type: SiteQuality
SIO_000300: 1.327e1

InbreedingCoeff
type: SiteQuality
SIO_000300: -1.0e-4

MQ
type: SiteQuality
SIO_000300: 6.0e1

GenotypeQuality
all individuals: 3718
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 10177
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 81
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 45
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 31915
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2436
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 47
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1098
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5772
bin: 9.75e1
variant carriers: 3

GenotypeQuality
all individuals: 3737
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1403
bin: 9.25e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11568
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10402
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 3
allele frequency: 4.496268097479092e-5
allele num: 66722
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16506
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.886233e6

QD
type: SiteQuality
SIO_000300: 1.287e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.1e-3

ClippingRankSum
type: SiteQuality
SIO_000300: -3.47e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 3.04e-1

FS
type: SiteQuality
SIO_000300: 3.65e-1

MQ
type: SiteQuality
SIO_000300: 5.932e1

MQRankSum
type: SiteQuality
SIO_000300: 5.26e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.185e0

VQSLOD
type: SiteQuality
SIO_000300: 1.72e0