1-46512187-A-AATAT
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512187
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512191
    reference: chr 1
allele count: 3
allele frequency: 2.475574333245313e-5
allele num: 121184
alternate allele: AATAT
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.731+35_731+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1016+35_1016+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1016+35_1016+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.839+35_839+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1715+35_1715+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.839+35_839+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1154+35_1154+36insATAT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1016+35_1016+36insATAT
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: VQSRTrancheINDEL97.00to99.00
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 382
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8072
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7740
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6914
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6121
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7691
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3672
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 468
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 564
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2539
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5236
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 745
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3137
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 86
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1553
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3663
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 439
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 626
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1053
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 150
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2077
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 227
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3738
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 179
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: East Asian
population: South Asian
population: African
population: Latino
population: Other
population: European (Non-Finnish)
reference allele: A
site quality: ReadPosRankSum
site quality: FS
site quality: VQSLOD
site quality: ClippingRankSum
site quality: DP
site quality: MQ
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: QD
site quality: BaseQRankSum

1-46512188-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512188
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512188
    reference: chr 1
allele count: 167
allele frequency: 1.378001485271062e-3
allele num: 121190
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.839+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.731+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.839+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1715+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1016+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1154+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1016+35T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1016+35T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 749
  bin: 7.75e1
  variant carriers: 11
genotype depth: GenotypeDepth
  all individuals: 3672
  bin: 5.75e1
  variant carriers: 19
genotype depth: GenotypeDepth
  all individuals: 568
  bin: 8.75e1
  variant carriers: 8
genotype depth: GenotypeDepth
  all individuals: 1064
  bin: 7.25e1
  variant carriers: 13
genotype depth: GenotypeDepth
  all individuals: 632
  bin: 8.25e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 6902
  bin: 4.75e1
  variant carriers: 13
genotype depth: GenotypeDepth
  all individuals: 8058
  bin: 3.75e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 1552
  bin: 6.75e1
  variant carriers: 9
genotype depth: GenotypeDepth
  all individuals: 2549
  bin: 6.25e1
  variant carriers: 18
genotype depth: GenotypeDepth
  all individuals: 7744
  bin: 3.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 430
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 361
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6125
  bin: 2.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 3148
  bin: 9.75e1
  variant carriers: 22
genotype depth: GenotypeDepth
  all individuals: 3703
  bin: 2.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 7680
  bin: 4.25e1
  variant carriers: 8
genotype depth: GenotypeDepth
  all individuals: 86
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5237
  bin: 5.25e1
  variant carriers: 17
genotype depth: GenotypeDepth
  all individuals: 441
  bin: 9.25e1
  variant carriers: 4
genotype quality: GenotypeQuality
  all individuals: 73
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3743
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2063
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3616
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 173
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3718
  bin: 9.25e1
  variant carriers: 0
num of homozygotes: 0
population: African
population: East Asian
population: Other
population: Latino
population: European (Non-Finnish)
population: European (Finnish)
population: South Asian
reference allele: A
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: MQ
site quality: BaseQRankSum
site quality: FS
site quality: ClippingRankSum
site quality: DP
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: QD

http://identifiers.org/exac.variant/1-46512195-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512195
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512195
    reference: chr 1
allele count: 1
allele frequency: 8.249191579225235e-6
allele num: 121224
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1715+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.731+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.839+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1016+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1016+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.839+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1154+28G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1016+28G>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1545
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 561
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5242
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6917
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7688
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2537
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 184
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8084
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3845
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 437
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7819
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 220
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1053
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3668
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3133
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 6335
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7812
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3558
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 104
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 79
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 111
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3617
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2082
  bin: 8.75e1
  variant carriers: 0
num of homozygotes: 0
population: Latino
population: South Asian
population: East Asian
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: Other
reference allele: C
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: FS
site quality: VQSLOD
site quality: DP
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: QD
site quality: MQ

1-46512204-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512204
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512204
    reference: chr 1
allele count: 1
allele frequency: 8.244159013339049e-6
allele num: 121298
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1715+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.839+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.731+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1154+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1016+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1016+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1016+19T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.839+19T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 99
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1053
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7846
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6916
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8081
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3667
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2537
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1545
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6460
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 65
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7688
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 52
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3957
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5243
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 437
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 561
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3132
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 37
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3623
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8130
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2074
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3818
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3732
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 37
  bin: 3.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Non-Finnish)
population: Latino
population: European (Finnish)
population: South Asian
population: African
population: East Asian
population: Other
reference allele: A
site quality: MQ
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: FS
site quality: ClippingRankSum
site quality: QD
site quality: DP
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: BaseQRankSum

1-46512209-T-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512209
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512209
    reference: chr 1
allele count: 3
allele frequency: 2.472676920033628e-5
allele num: 121326
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.839+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1715+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1016+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1016+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.731+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1154+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1016+14A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.839+14A>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 36
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6496
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 561
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7689
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 64
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 437
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6917
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 5244
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3990
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 36
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2537
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3667
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8078
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7857
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1546
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3132
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 33395
  bin: 9.75e1
  variant carriers: 3
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2075
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2084
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 32
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 7.5e0
  variant carriers: 0
num of homozygotes: 0
population: Latino
population: European (Non-Finnish)
population: European (Finnish)
population: African
population: South Asian
population: East Asian
population: Other
reference allele: T
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: FS
site quality: MQ
site quality: DP
site quality: VQSLOD
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: QD

1-46512227-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512227
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512227
    reference: chr 1
allele count: 1
allele frequency: 8.238861059847087e-6
allele num: 121376
alternate allele: G
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1012G>C
  hgvsp: ENSP00000262741.5:p.Asp338His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1012G>C
  hgvsp: ENSP00000361075.1:p.Asp338His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1012G>C
  hgvsp: ENSP00000412546.1:p.Asp338His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1711G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.727G>C
  hgvsp: ENSP00000342484.6:p.Asp243His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.835G>C
  hgvsp: ENSP00000391431.1:p.Asp279His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1150G>C
  hgvsp: ENSP00000439913.1:p.Asp384His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.835G>C
  hgvsp: ENSP00000346188.4:p.Asp279His
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2537
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 20
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7867
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5243
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3991
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8080
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1547
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7686
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 437
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 561
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6577
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3666
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6916
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3132
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 3617
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2085
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8337
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Asp338His
num of homozygotes: 0
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: Other
population: Latino
population: East Asian
population: South Asian
reference allele: C
site quality: InbreedingCoeff
site quality: MQ
site quality: DP
site quality: QD
site quality: BaseQRankSum
site quality: VQSLOD
site quality: MQRankSum
site quality: FS
site quality: ClippingRankSum
site quality: ReadPosRankSum

1-46512235-T-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512235
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512235
    reference: chr 1
allele count: 3
allele frequency: 2.471454698235381e-5
allele num: 121386
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.1004A>C
  hgvsp: ENSP00000412546.1:p.Glu335Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1142A>C
  hgvsp: ENSP00000439913.1:p.Glu381Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.719A>C
  hgvsp: ENSP00000342484.6:p.Glu240Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.827A>C
  hgvsp: ENSP00000391431.1:p.Glu276Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1703A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.1004A>C
  hgvsp: ENSP00000262741.5:p.Glu335Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.827A>C
  hgvsp: ENSP00000346188.4:p.Glu276Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.1004A>C
  hgvsp: ENSP00000361075.1:p.Glu335Ala
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7868
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3666
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 13
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 560
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7685
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 437
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5243
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2538
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3134
  bin: 9.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 6585
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6915
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4001
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8079
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1547
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2075
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Glu335Ala
num of homozygotes: 0
population: African
population: East Asian
population: European (Non-Finnish)
population: South Asian
population: European (Finnish)
population: Latino
population: Other
reference allele: T
site quality: MQ
site quality: MQRankSum
site quality: ClippingRankSum
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: FS
site quality: DP
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: QD

1-46512247-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512247
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512247
    reference: chr 1
allele count: 1
allele frequency: 8.237775141689733e-6
allele num: 121392
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.815G>A
  hgvsp: ENSP00000391431.1:p.Gly272Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.992G>A
  hgvsp: ENSP00000412546.1:p.Gly331Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.815G>A
  hgvsp: ENSP00000346188.4:p.Gly272Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.992G>A
  hgvsp: ENSP00000262741.5:p.Gly331Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1130G>A
  hgvsp: ENSP00000439913.1:p.Gly377Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.707G>A
  hgvsp: ENSP00000342484.6:p.Gly236Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1691G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.992G>A
  hgvsp: ENSP00000361075.1:p.Gly331Glu
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 437
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4000
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7866
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 9
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8081
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3132
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 559
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7686
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2538
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3666
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6915
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1548
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6592
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5243
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 4.75e1
  variant carriers: 0
hgvs: p.Gly331Glu
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: Other
population: Latino
population: East Asian
population: African
population: South Asian
reference allele: C
site quality: MQ
site quality: QD
site quality: DP
site quality: VQSLOD
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: FS
site quality: BaseQRankSum
site quality: InbreedingCoeff

1-46512258-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512258
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512258
    reference: chr 1
allele count: 5
allele frequency: 4.118751853438334e-5
allele num: 121396
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1680T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.981T>C
  hgvsp: ENST00000372006.1:c.981T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.804T>C
  hgvsp: ENST00000354242.4:c.804T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.981T>C
  hgvsp: ENST00000262741.5:c.981T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.696T>C
  hgvsp: ENST00000340332.6:c.696T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.804T>C
  hgvsp: ENST00000423209.1:c.804T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.981T>C
  hgvsp: ENST00000420542.1:c.981T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1119T>C
  hgvsp: ENST00000540385.1:c.1119T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 6594
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 438
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3666
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7863
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1548
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2538
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 9
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5242
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4004
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3135
  bin: 9.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6914
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7686
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 559
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8080
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2075
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3562
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8372
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3731
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Asn327Asn
num of homozygotes: 0
population: Latino
population: African
population: European (Non-Finnish)
population: European (Finnish)
population: Other
population: South Asian
population: East Asian
reference allele: A
site quality: QD
site quality: FS
site quality: BaseQRankSum
site quality: MQRankSum
site quality: DP
site quality: MQ
site quality: VQSLOD
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: ReadPosRankSum

1-46512264-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512264
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512264
    reference: chr 1
allele count: 5
allele frequency: 4.119023297195769e-5
allele num: 121388
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.690C>T
  hgvsp: ENST00000340332.6:c.690C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1113C>T
  hgvsp: ENST00000540385.1:c.1113C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.975C>T
  hgvsp: ENST00000262741.5:c.975C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1674C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.798C>T
  hgvsp: ENST00000423209.1:c.798C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.975C>T
  hgvsp: ENST00000372006.1:c.975C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.975C>T
  hgvsp: ENST00000420542.1:c.975C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.798C>T
  hgvsp: ENST00000354242.4:c.798C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 12
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6595
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3998
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2537
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 560
  bin: 8.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 438
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7861
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8080
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1547
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6915
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3135
  bin: 9.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 3667
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5241
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7686
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3616
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3731
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Arg325Arg
num of homozygotes: 0
population: Other
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
population: East Asian
population: Latino
population: African
reference allele: G
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: FS
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: QD
site quality: MQRankSum
site quality: DP
site quality: ReadPosRankSum
site quality: MQ

1-46512265-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512265
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512265
    reference: chr 1
allele count: 1
allele frequency: 8.238046594391538e-6
allele num: 121388
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.797G>A
  hgvsp: ENSP00000391431.1:p.Arg266His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.974G>A
  hgvsp: ENSP00000412546.1:p.Arg325His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.974G>A
  hgvsp: ENSP00000361075.1:p.Arg325His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1112G>A
  hgvsp: ENSP00000439913.1:p.Arg371His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1673G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.689G>A
  hgvsp: ENSP00000342484.6:p.Arg230His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.974G>A
  hgvsp: ENSP00000262741.5:p.Arg325His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.797G>A
  hgvsp: ENSP00000346188.4:p.Arg266His
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 6915
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3997
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6598
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3131
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1052
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7687
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3667
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2537
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 438
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 740
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1548
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 625
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5242
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8080
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7861
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 559
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2083
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2075
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Arg325His
num of homozygotes: 0
population: Latino
population: African
population: South Asian
population: European (Non-Finnish)
population: European (Finnish)
population: East Asian
population: Other
reference allele: C
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: FS
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: BaseQRankSum
site quality: MQ
site quality: QD
site quality: DP

1-46512266-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512266
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512266
    reference: chr 1
allele count: 138
allele frequency: 1.136831699481012e-3
allele num: 121390
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.688C>T
  hgvsp: ENSP00000342484.6:p.Arg230Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.973C>T
  hgvsp: ENSP00000361075.1:p.Arg325Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.796C>T
  hgvsp: ENSP00000346188.4:p.Arg266Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1672C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.796C>T
  hgvsp: ENSP00000391431.1:p.Arg266Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.973C>T
  hgvsp: ENSP00000262741.5:p.Arg325Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1111C>T
  hgvsp: ENSP00000439913.1:p.Arg371Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.973C>T
  hgvsp: ENSP00000412546.1:p.Arg325Cys
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3657
  bin: 5.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 3209
  bin: 9.75e1
  variant carriers: 92
genotype depth: GenotypeDepth
  all individuals: 6906
  bin: 4.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 1055
  bin: 7.25e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 446
  bin: 9.25e1
  variant carriers: 8
genotype depth: GenotypeDepth
  all individuals: 7673
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2524
  bin: 6.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 626
  bin: 8.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 1548
  bin: 6.75e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 5231
  bin: 5.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 11
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3985
  bin: 2.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 12
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8061
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7854
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 6
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 562
  bin: 8.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 745
  bin: 7.75e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 6595
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8358
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3611
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 2.25e1
  variant carriers: 0
hgvs: p.Arg325Cys
num of homozygotes: 1
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
population: East Asian
population: African
population: Other
population: Latino
reference allele: G
site quality: BaseQRankSum
site quality: FS
site quality: MQ
site quality: DP
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: QD
site quality: ClippingRankSum
site quality: VQSLOD
site quality: MQRankSum

1-46512289-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512289
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512289
    reference: chr 1
allele count: 120
allele frequency: 9.887610823637982e-4
allele num: 121364
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.665A>G
  hgvsp: ENSP00000342484.6:p.Asn222Ser
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1649A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.950A>G
  hgvsp: ENSP00000361075.1:p.Asn317Ser
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.773A>G
  hgvsp: ENSP00000391431.1:p.Asn258Ser
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1088A>G
  hgvsp: ENSP00000439913.1:p.Asn363Ser
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.950A>G
  hgvsp: ENSP00000262741.5:p.Asn317Ser
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.950A>G
  hgvsp: ENSP00000412546.1:p.Asn317Ser
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.773A>G
  hgvsp: ENSP00000346188.4:p.Asn258Ser
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 743
  bin: 7.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 7871
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2515
  bin: 6.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 8077
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6597
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 30
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 21
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1539
  bin: 6.75e1
  variant carriers: 5
genotype depth: GenotypeDepth
  all individuals: 557
  bin: 8.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 3213
  bin: 9.75e1
  variant carriers: 84
genotype depth: GenotypeDepth
  all individuals: 1046
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7675
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6900
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3948
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 443
  bin: 9.25e1
  variant carriers: 7
genotype depth: GenotypeDepth
  all individuals: 3651
  bin: 5.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 631
  bin: 8.25e1
  variant carriers: 10
genotype depth: GenotypeDepth
  all individuals: 5231
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 18
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3732
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3561
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Asn317Ser
num of homozygotes: 0
population: East Asian
population: South Asian
population: Other
population: European (Finnish)
population: African
population: European (Non-Finnish)
population: Latino
reference allele: T
site quality: MQ
site quality: FS
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: QD
site quality: ReadPosRankSum
site quality: DP
site quality: MQRankSum
site quality: BaseQRankSum

1-46512291-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512291
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512291
    reference: chr 1
allele count: 14
allele frequency: 1.153535586572846e-4
allele num: 121366
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.948C>T
  hgvsp: ENST00000372006.1:c.948C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.771C>T
  hgvsp: ENST00000423209.1:c.771C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1086C>T
  hgvsp: ENST00000540385.1:c.1086C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.771C>T
  hgvsp: ENST00000354242.4:c.771C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.948C>T
  hgvsp: ENST00000420542.1:c.948C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.663C>T
  hgvsp: ENST00000340332.6:c.663C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1647C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.948C>T
  hgvsp: ENST00000262741.5:c.948C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3949
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 30
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6610
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2523
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 436
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1539
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 7688
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5240
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 21
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3660
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6909
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1051
  bin: 7.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 19
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7891
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 742
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3133
  bin: 9.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 553
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8090
  bin: 3.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 3568
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3736
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 33319
  bin: 9.75e1
  variant carriers: 14
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Leu316Leu
num of homozygotes: 0
population: East Asian
population: African
population: South Asian
population: European (Finnish)
population: European (Non-Finnish)
population: Other
population: Latino
reference allele: G
site quality: VQSLOD
site quality: DP
site quality: ReadPosRankSum
site quality: QD
site quality: MQ
site quality: BaseQRankSum
site quality: MQRankSum
site quality: FS
site quality: ClippingRankSum
site quality: InbreedingCoeff

1-46512302-CAGAGG-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512302
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512297
    reference: chr 1
allele count: 4
allele frequency: 3.297011259293451e-5
allele num: 121322
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.942-10_942-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.657-10_657-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1080-10_1080-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1641-10_1641-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.942-10_942-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.942-10_942-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.765-10_765-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.765-10_765-6delCCTCT
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: splice region
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 41
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7694
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8089
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3660
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3129
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 5240
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6908
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 7882
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1538
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 554
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2523
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3877
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6621
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 435
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 742
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1048
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 32
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 76
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8294
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 22
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
hgvs: c.942-10_942-6delCCTCT
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: East Asian
population: African
population: South Asian
population: European (Non-Finnish)
population: Other
reference allele: CAGAGG
site quality: DP
site quality: QD
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: MQ
site quality: BaseQRankSum
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: ClippingRankSum

1-46512318-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512318
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512318
    reference: chr 1
allele count: 1
allele frequency: 8.244974687927709e-6
allele num: 121286
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1641-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.942-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.942-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.657-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.765-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1080-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.942-21C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.765-21C>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 8086
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3660
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6908
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3129
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 254
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6531
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 175
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 57
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1048
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1537
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5241
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3631
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7878
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7693
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 554
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 741
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 435
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2522
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2081
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 80
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3736
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 84
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 27
  bin: 4.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Non-Finnish)
population: East Asian
population: European (Finnish)
population: Latino
population: South Asian
population: Other
population: African
reference allele: G
site quality: DP
site quality: MQRankSum
site quality: MQ
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: FS
site quality: QD
site quality: ClippingRankSum

1-46512327-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512327
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512327
    reference: chr 1
allele count: 1
allele frequency: 8.248375070111188e-6
allele num: 121236
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.765-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.942-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.657-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.942-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1641-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.942-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1080-30A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.765-30A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1537
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6906
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 533
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 741
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8079
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3128
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7819
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6373
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 62
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 406
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 554
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5241
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3661
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1048
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7691
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3340
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2522
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 435
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 68
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 91
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 94
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 238
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 145
  bin: 2.75e1
  variant carriers: 0
num of homozygotes: 0
population: South Asian
population: European (Finnish)
population: East Asian
population: Latino
population: Other
population: African
population: European (Non-Finnish)
reference allele: T
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: QD
site quality: DP
site quality: ClippingRankSum
site quality: VQSLOD
site quality: MQRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: MQ

1-46512331-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512331
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512331
    reference: chr 1
allele count: 4
allele frequency: 3.299513321785036e-5
allele num: 121230
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.942-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.765-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1080-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.942-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.942-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.657-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1641-34A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.765-34A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 554
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5240
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 68
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1048
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 976
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3662
  bin: 5.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 8
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 480
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7762
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2522
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1537
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 741
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6216
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 435
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7690
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3041
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3128
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6904
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8072
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3665
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 18
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2036
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 191
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 179
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 103
  bin: 5.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: East Asian
population: European (Non-Finnish)
population: Latino
population: African
population: South Asian
population: Other
reference allele: T
site quality: BaseQRankSum
site quality: MQ
site quality: ClippingRankSum
site quality: VQSLOD
site quality: DP
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: ReadPosRankSum
site quality: QD

1-46512338-T-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512338
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512338
    reference: chr 1
allele count: 1
allele frequency: 8.251642076773278e-6
allele num: 121188
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.765-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.765-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.942-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1080-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.942-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1641-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.942-41A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.657-41A>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 5836
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2938
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 622
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3660
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2521
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6904
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 9
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 435
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 741
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7638
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1048
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8061
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1574
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1536
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7683
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 554
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5239
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 497
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3128
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 616
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 258
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 16
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 126
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 485
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3594
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 13
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 245
  bin: 2.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: Other
population: South Asian
population: European (Non-Finnish)
population: African
population: East Asian
reference allele: T
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: DP
site quality: MQRankSum
site quality: ClippingRankSum
site quality: FS
site quality: MQ
site quality: VQSLOD
site quality: QD

1-46512346-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46512346
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46512346
    reference: chr 1
allele count: 1
allele frequency: 8.258865892535638e-6
allele num: 121082
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.942-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.657-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.765-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1080-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1641-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.942-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.942-49C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.765-49C>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 621
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 553
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6900
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1048
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 741
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3128
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3759
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1611
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3658
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7674
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 5457
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 500
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 435
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 110
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8000
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2521
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1536
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5237
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7209
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 20
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4272
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3728
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1125
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 287
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 497
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3447
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3320
  bin: 6.75e1
  variant carriers: 0
num of homozygotes: 0
population: African
population: European (Finnish)
population: Other
population: European (Non-Finnish)
population: South Asian
population: Latino
population: East Asian
reference allele: G
site quality: BaseQRankSum
site quality: QD
site quality: FS
site quality: ClippingRankSum
site quality: VQSLOD
site quality: DP
site quality: MQ
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: ReadPosRankSum

1-46521434-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521434
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521434
    reference: chr 1
allele count: 5
allele frequency: 4.511006856730422e-5
allele num: 110840
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6167C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.941+33C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1640+33C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.941+33C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1079+33C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.941+33C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6167C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6167C>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1820
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3518
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2294
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2653
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15392
  bin: 9.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 1426
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3302
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3189
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3533
  bin: 7.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2210
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1844
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2069
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3037
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2019
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 73
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2993
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3078
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3269
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2597
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 509
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 431
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 21
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 334
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 189
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 36
  bin: 3.75e1
  variant carriers: 0
num of homozygotes: 0
population: Latino
population: European (Finnish)
population: South Asian
population: Other
population: East Asian
population: African
population: European (Non-Finnish)
reference allele: G
site quality: MQ
site quality: MQRankSum
site quality: DP
site quality: BaseQRankSum
site quality: FS
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: QD
site quality: ClippingRankSum

1-46521450-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521450
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521450
    reference: chr 1
allele count: 0
allele frequency: 0.0e0
allele num: 111234
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6151T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6151T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1640+17T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1079+17T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6151T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.941+17T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.941+17T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.941+17T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: AC_Adj0_Filter
genotype depth: GenotypeDepth
  all individuals: 2653
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2018
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1449
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1824
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1842
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3037
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3078
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2216
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2297
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2028
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3302
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 357
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2597
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2938
  bin: 7.5e0
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3518
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 64
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3210
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15392
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3533
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3269
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 117
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 138
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 13
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47259
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 5.25e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 637
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 62
  bin: 3.75e1
  variant carriers: 0
num of homozygotes: 0
population: African
population: East Asian
population: European (Non-Finnish)
population: European (Finnish)
population: Latino
population: Other
population: South Asian
reference allele: A
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: DP
site quality: ReadPosRankSum
site quality: MQ
site quality: QD
site quality: FS
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: VQSLOD

1-46521451-C-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521451
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521451
    reference: chr 1
allele count: 40
allele frequency: 3.595376346019019e-4
allele num: 111254
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.941+16G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.941+16G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1640+16G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6150G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6150G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.941+16G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1079+16G>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6150G>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2987
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1959
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3532
  bin: 7.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 2593
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 2292
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 370
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1452
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2015
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3211
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3266
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 15412
  bin: 9.75e1
  variant carriers: 28
genotype depth: GenotypeDepth
  all individuals: 2655
  bin: 9.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 2217
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1819
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 143
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 637
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 138
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 18
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 161
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 436
  bin: 8.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: South Asian
population: Latino
population: East Asian
population: African
population: Other
population: European (Non-Finnish)
reference allele: C
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: MQ
site quality: BaseQRankSum
site quality: FS
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: DP
site quality: QD

1-46521451-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521451
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521451
    reference: chr 1
allele count: 1
allele frequency: 8.988440865047549e-6
allele num: 111254
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.941+16G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1640+16G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.941+16G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6150G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1079+16G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.941+16G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6150G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6150G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1452
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 70
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2987
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2217
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3211
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2593
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1959
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3532
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 370
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2292
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15412
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1819
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2655
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2015
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3266
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47260
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 1830
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 637
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 161
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 138
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 610
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1114
  bin: 6.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: African
population: Other
population: East Asian
population: European (Non-Finnish)
population: South Asian
reference allele: C
site quality: BaseQRankSum
site quality: MQ
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: QD
site quality: DP
site quality: ClippingRankSum

1-46521459-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521459
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521459
    reference: chr 1
allele count: 2
allele frequency: 1.792692983399663e-5
allele num: 111564
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.941+8G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.941+8G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6142G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6142G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6142G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1640+8G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.941+8G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1079+8G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: splice region
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1819
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3221
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 490
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3356
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1419
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15414
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 103
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2222
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3532
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2656
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3080
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1487
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2015
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2292
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 79
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1342
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 478
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 169
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 660
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 610
  bin: 9.25e1
  variant carriers: 0
hgvs: c.941+8G>A
num of homozygotes: 0
population: African
population: Other
population: South Asian
population: Latino
population: East Asian
population: European (Finnish)
population: European (Non-Finnish)
reference allele: C
site quality: VQSLOD
site quality: FS
site quality: BaseQRankSum
site quality: MQ
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: DP
site quality: MQRankSum
site quality: QD
site quality: ReadPosRankSum

1-46521467-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521467
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521467
    reference: chr 1
allele count: 1
allele frequency: 8.919015340706385e-6
allele num: 112120
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  consequence: splice_region_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1640T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6134T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6134T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  consequence: splice_region_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.941T>C
  hgvsp: ENSP00000361075.1:p.Val314Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  consequence: splice_region_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1079T>C
  hgvsp: ENSP00000439913.1:p.Val360Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  consequence: splice_region_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.941T>C
  hgvsp: ENSP00000262741.5:p.Val314Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  consequence: splice_region_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.941T>C
  hgvsp: ENSP00000412546.1:p.Val314Ala
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6134T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3532
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3597
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2226
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 149
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2655
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1821
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 595
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1580
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2015
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 936
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15415
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3233
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2292
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3080
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 231
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 610
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 97
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 17
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 119
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 914
  bin: 7.5e0
  variant carriers: 0
hgvs: p.Val314Ala
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: European (Non-Finnish)
population: Other
population: East Asian
population: South Asian
population: African
reference allele: A
site quality: BaseQRankSum
site quality: FS
site quality: VQSLOD
site quality: MQRankSum
site quality: MQ
site quality: ReadPosRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: QD
site quality: ClippingRankSum

1-46521473-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521473
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521473
    reference: chr 1
allele count: 1
allele frequency: 8.884466398948079e-6
allele num: 112556
alternate allele: C
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.935A>G
  hgvsp: ENSP00000262741.5:p.His312Arg
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.935A>G
  hgvsp: ENSP00000361075.1:p.His312Arg
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.935A>G
  hgvsp: ENSP00000412546.1:p.His312Arg
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6128A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1073A>G
  hgvsp: ENSP00000439913.1:p.His358Arg
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1634A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6128A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6128A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 673
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3244
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3592
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2231
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 702
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3518
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1821
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2015
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3080
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3532
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15416
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1688
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3414
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 262
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 611
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4218
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 28
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 57
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 479
  bin: 7.25e1
  variant carriers: 0
hgvs: p.His312Arg
num of homozygotes: 0
population: European (Non-Finnish)
population: East Asian
population: Latino
population: South Asian
population: European (Finnish)
population: Other
population: African
reference allele: T
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: VQSLOD
site quality: FS
site quality: MQRankSum
site quality: DP
site quality: MQ
site quality: ReadPosRankSum
site quality: QD
site quality: BaseQRankSum

1-46521477-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521477
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521477
    reference: chr 1
allele count: 1
allele frequency: 8.853004709798506e-6
allele num: 112956
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1069C>T
  hgvsp: ENSP00000439913.1:p.Gln357Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1630C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6124C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.931C>T
  hgvsp: ENSP00000361075.1:p.Gln311Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.931C>T
  hgvsp: ENSP00000262741.5:p.Gln311Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6124C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.931C>T
  hgvsp: ENSP00000412546.1:p.Gln311Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6124C>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: stop gained
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2237
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15418
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1794
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3263
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 227
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 700
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2015
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 550
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3558
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3531
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1822
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3080
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 152
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47261
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 56
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 487
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 68
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4302
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Gln311Ter
num of homozygotes: 0
population: African
population: European (Finnish)
population: South Asian
population: Other
population: East Asian
population: European (Non-Finnish)
population: Latino
reference allele: G
site quality: DP
site quality: BaseQRankSum
site quality: MQRankSum
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: FS
site quality: MQ
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: QD

1-46521482-C-CG
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521482
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521483
    reference: chr 1
allele count: 1
allele frequency: 8.807779030439684e-6
allele num: 113536
alternate allele: CG
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1624dupC
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6118dupC
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6118dupC
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1063dupC
  hgvsp: ENSP00000439913.1:p.Arg355ProfsTer25
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.925dupC
  hgvsp: ENSP00000361075.1:p.Arg309ProfsTer25
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6118dupC
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.925dupC
  hgvsp: ENSP00000262741.5:p.Arg309ProfsTer25
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.925dupC
  hgvsp: ENSP00000412546.1:p.Arg309ProfsTer25
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: frameshift
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3305
  bin: 8.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3373
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3531
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 753
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2051
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3080
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15418
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 255
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2014
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 384
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2245
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1822
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3276
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47261
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 488
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 55
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 165
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1150
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 412
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31
  bin: 5.75e1
  variant carriers: 0
hgvs: p.Arg309ProfsTer25
num of homozygotes: 0
population: East Asian
population: Other
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
population: Latino
population: African
reference allele: C
site quality: InbreedingCoeff
site quality: QD
site quality: ClippingRankSum
site quality: MQ
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: FS
site quality: MQRankSum
site quality: DP
site quality: VQSLOD

1-46521484-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521484
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521484
    reference: chr 1
allele count: 1
allele frequency: 8.761477535571598e-6
allele num: 114136
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1623C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.924C>G
  hgvsp: ENSP00000361075.1:p.Ile308Met
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.924C>G
  hgvsp: ENSP00000412546.1:p.Ile308Met
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6117C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6117C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1062C>G
  hgvsp: ENSP00000439913.1:p.Ile354Met
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.924C>G
  hgvsp: ENSP00000262741.5:p.Ile308Met
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6117C>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 711
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3531
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 272
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1822
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3236
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 312
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15418
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2248
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1841
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2258
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3301
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2014
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 492
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1177
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 666
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 55
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 46
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 69
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 612
  bin: 9.25e1
  variant carriers: 0
hgvs: p.Ile308Met
num of homozygotes: 0
population: East Asian
population: African
population: European (Non-Finnish)
population: European (Finnish)
population: Other
population: South Asian
population: Latino
reference allele: G
site quality: MQRankSum
site quality: FS
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: QD
site quality: DP

1-46521503-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521503
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521503
    reference: chr 1
allele count: 1
allele frequency: 8.492713252029759e-6
allele num: 117748
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1043T>C
  hgvsp: ENSP00000439913.1:p.Leu348Pro
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6098T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.905T>C
  hgvsp: ENSP00000412546.1:p.Leu302Pro
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1604T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6098T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.905T>C
  hgvsp: ENSP00000262741.5:p.Leu302Pro
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6098T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.905T>C
  hgvsp: ENSP00000361075.1:p.Leu302Pro
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3531
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1843
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 264
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1718
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 488
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2345
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1829
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 85
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15418
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2014
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3596
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3837
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 549
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 61
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1376
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 714
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 737
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 185
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47
  bin: 5.75e1
  variant carriers: 0
hgvs: p.Leu302Pro
num of homozygotes: 0
population: Latino
population: South Asian
population: Other
population: European (Finnish)
population: European (Non-Finnish)
population: East Asian
population: African
reference allele: A
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: QD
site quality: ClippingRankSum
site quality: DP
site quality: VQSLOD
site quality: BaseQRankSum
site quality: MQ
site quality: ReadPosRankSum
site quality: FS

1-46521504-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521504
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521504
    reference: chr 1
allele count: 1
allele frequency: 8.482771491101573e-6
allele num: 117886
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.904C>T
  hgvsp: ENST00000372006.1:c.904C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1042C>T
  hgvsp: ENST00000540385.1:c.1042C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.904C>T
  hgvsp: ENST00000420542.1:c.904C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1603C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6097C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.904C>T
  hgvsp: ENST00000262741.5:c.904C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6097C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6097C>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3625
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3517
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2014
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1647
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1844
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 79
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15418
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 258
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3907
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 463
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2354
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3531
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1829
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 23
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 742
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 14
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47265
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 6305
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1665
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 98
  bin: 4.75e1
  variant carriers: 0
hgvs: p.Leu302Leu
num of homozygotes: 0
population: African
population: European (Finnish)
population: European (Non-Finnish)
population: Other
population: South Asian
population: Latino
population: East Asian
reference allele: G
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: MQ
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: DP
site quality: FS
site quality: ClippingRankSum
site quality: QD

1-46521505-G-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521505
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521505
    reference: chr 1
allele count: 2
allele frequency: 1.693738249690893e-5
allele num: 118082
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6096C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.903C>A
  hgvsp: ENSP00000361075.1:p.Asp301Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6096C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.903C>A
  hgvsp: ENSP00000262741.5:p.Asp301Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1041C>A
  hgvsp: ENSP00000439913.1:p.Asp347Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6096C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.903C>A
  hgvsp: ENSP00000412546.1:p.Asp301Glu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1602C>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2592
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3641
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4000
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1832
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3530
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 240
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 71
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 451
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3516
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1568
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15420
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1844
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2014
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2359
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 172
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 166
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 13
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1402
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47267
  bin: 9.75e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 6437
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Asp301Glu
num of homozygotes: 0
population: East Asian
population: European (Non-Finnish)
population: Other
population: European (Finnish)
population: African
population: South Asian
population: Latino
reference allele: G
site quality: FS
site quality: MQRankSum
site quality: QD
site quality: VQSLOD
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: InbreedingCoeff
site quality: MQ
site quality: DP

1-46521511-T-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521511
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521511
    reference: chr 1
allele count: 1
allele frequency: 8.399408681628814e-6
allele num: 119056
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.897A>C
  hgvsp: ENSP00000412546.1:p.Lys299Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6090A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.897A>C
  hgvsp: ENSP00000262741.5:p.Lys299Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6090A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1035A>C
  hgvsp: ENSP00000439913.1:p.Lys345Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.897A>C
  hgvsp: ENSP00000361075.1:p.Lys299Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6090A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1596A>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2399
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1829
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 35
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3529
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1125
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3760
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4519
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3081
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15421
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 309
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 185
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1845
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2291
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3516
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3304
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3265
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3033
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2591
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2654
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2014
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 19
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 637
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 47268
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 35
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 130
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6871
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1131
  bin: 2.25e1
  variant carriers: 0
hgvs: p.Lys299Asn
num of homozygotes: 0
population: European (Finnish)
population: Latino
population: European (Non-Finnish)
population: African
population: South Asian
population: Other
population: East Asian
reference allele: T
site quality: BaseQRankSum
site quality: MQ
site quality: DP
site quality: VQSLOD
site quality: FS
site quality: QD
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: MQRankSum
site quality: ReadPosRankSum

1-46521517-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521517
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521517
    reference: chr 1
allele count: 82425
allele frequency: 6.81040750900618e-1
allele num: 121028
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.891C>T
  hgvsp: ENST00000372006.1:c.891C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6084C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.891C>T
  hgvsp: ENST00000262741.5:c.891C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6084C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.891C>T
  hgvsp: ENST00000420542.1:c.891C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1590C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6084C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1029C>T
  hgvsp: ENST00000540385.1:c.1029C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 970
  bin: 8.75e1
  variant carriers: 931
genotype depth: GenotypeDepth
  all individuals: 905
  bin: 7.75e1
  variant carriers: 857
genotype depth: GenotypeDepth
  all individuals: 2132
  bin: 3.25e1
  variant carriers: 1018
genotype depth: GenotypeDepth
  all individuals: 134
  bin: 7.5e0
  variant carriers: 78
genotype depth: GenotypeDepth
  all individuals: 845
  bin: 6.75e1
  variant carriers: 808
genotype depth: GenotypeDepth
  all individuals: 537
  bin: 5.25e1
  variant carriers: 490
genotype depth: GenotypeDepth
  all individuals: 565
  bin: 4.75e1
  variant carriers: 487
genotype depth: GenotypeDepth
  all individuals: 1099
  bin: 3.75e1
  variant carriers: 768
genotype depth: GenotypeDepth
  all individuals: 986
  bin: 8.25e1
  variant carriers: 956
genotype depth: GenotypeDepth
  all individuals: 2358
  bin: 2.25e1
  variant carriers: 919
genotype depth: GenotypeDepth
  all individuals: 714
  bin: 5.75e1
  variant carriers: 660
genotype depth: GenotypeDepth
  all individuals: 301
  bin: 1.25e1
  variant carriers: 272
genotype depth: GenotypeDepth
  all individuals: 1022
  bin: 9.25e1
  variant carriers: 991
genotype depth: GenotypeDepth
  all individuals: 567
  bin: 1.75e1
  variant carriers: 548
genotype depth: GenotypeDepth
  all individuals: 706
  bin: 4.25e1
  variant carriers: 557
genotype depth: GenotypeDepth
  all individuals: 41573
  bin: 9.75e1
  variant carriers: 41344
genotype depth: GenotypeDepth
  all individuals: 6
  bin: 2.5e0
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 855
  bin: 7.25e1
  variant carriers: 820
genotype depth: GenotypeDepth
  all individuals: 3658
  bin: 2.75e1
  variant carriers: 1043
genotype depth: GenotypeDepth
  all individuals: 771
  bin: 6.25e1
  variant carriers: 726
genotype quality: GenotypeQuality
  all individuals: 53
  bin: 4.25e1
  variant carriers: 50
genotype quality: GenotypeQuality
  all individuals: 53009
  bin: 9.75e1
  variant carriers: 52281
genotype quality: GenotypeQuality
  all individuals: 1011
  bin: 6.75e1
  variant carriers: 215
genotype quality: GenotypeQuality
  all individuals: 157
  bin: 8.75e1
  variant carriers: 114
genotype quality: GenotypeQuality
  all individuals: 413
  bin: 8.25e1
  variant carriers: 235
genotype quality: GenotypeQuality
  all individuals: 348
  bin: 7.25e1
  variant carriers: 143
genotype quality: GenotypeQuality
  all individuals: 82
  bin: 2.25e1
  variant carriers: 26
hgvs: p.Ser297Ser
num of homozygotes: 28244
population: Other
population: East Asian
population: European (Non-Finnish)
population: European (Finnish)
population: African
population: South Asian
population: Latino
reference allele: G
site quality: VQSLOD
site quality: DP
site quality: ReadPosRankSum
site quality: BaseQRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: MQ
site quality: QD
site quality: MQRankSum
site quality: ClippingRankSum

http://identifiers.org/exac.variant/1-46521523-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521523
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521523
    reference: chr 1
allele count: 1
allele frequency: 8.256138438929344e-6
allele num: 121122
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6078G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.885G>T
  hgvsp: ENSP00000262741.5:p.Met295Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.885G>T
  hgvsp: ENSP00000412546.1:p.Met295Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6078G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1023G>T
  hgvsp: ENSP00000439913.1:p.Met341Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6078G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.885G>T
  hgvsp: ENSP00000361075.1:p.Met295Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1584G>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2731
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 388
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 284
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3243
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2539
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 128
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4128
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1880
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23320
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1484
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2967
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1495
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1583
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1737
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1488
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3323
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 148
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 472
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 179
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 865
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 110
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1569
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Met295Ile
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: Latino
population: East Asian
population: Other
population: South Asian
population: African
reference allele: C
site quality: MQ
site quality: MQRankSum
site quality: BaseQRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: DP
site quality: QD
site quality: VQSLOD
site quality: ClippingRankSum

1-46521523-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521523
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521523
    reference: chr 1
allele count: 1
allele frequency: 8.256138438929344e-6
allele num: 121122
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.885G>A
  hgvsp: ENSP00000361075.1:p.Met295Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.885G>A
  hgvsp: ENSP00000262741.5:p.Met295Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6078G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.885G>A
  hgvsp: ENSP00000412546.1:p.Met295Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6078G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1023G>A
  hgvsp: ENSP00000439913.1:p.Met341Ile
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1584G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6078G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 388
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2539
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1484
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2731
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 128
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23320
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1737
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1495
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1880
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4128
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1583
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1488
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3243
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 284
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3323
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2967
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49048
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 82
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 120
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 179
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 148
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 946
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 865
  bin: 9.25e1
  variant carriers: 0
hgvs: p.Met295Ile
num of homozygotes: 0
population: African
population: Latino
population: European (Non-Finnish)
population: East Asian
population: Other
population: European (Finnish)
population: South Asian
reference allele: C
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: DP
site quality: QD
site quality: VQSLOD
site quality: MQ
site quality: FS
site quality: ReadPosRankSum
site quality: MQRankSum

1-46521524-A-AT
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521524
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521525
    reference: chr 1
allele count: 3
allele frequency: 2.476800634060962e-5
allele num: 121124
alternate allele: AT
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1582dupA
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.883dupA
  hgvsp: ENSP00000412546.1:p.Met295AsnfsTer3
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.883dupA
  hgvsp: ENSP00000361075.1:p.Met295AsnfsTer3
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.883dupA
  hgvsp: ENSP00000262741.5:p.Met295AsnfsTer3
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: frameshift_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1021dupA
  hgvsp: ENSP00000439913.1:p.Met341AsnfsTer3
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6076dupA
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6076dupA
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6076dupA
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: frameshift
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3244
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 362
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2550
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2967
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2740
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1495
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 280
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3323
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1886
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 120
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4139
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1736
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1488
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1585
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1484
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23319
  bin: 9.75e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 87
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49049
  bin: 9.75e1
  variant carriers: 3
genotype quality: GenotypeQuality
  all individuals: 473
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 145
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 12
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 94
  bin: 5.25e1
  variant carriers: 0
hgvs: p.Met295AsnfsTer3
num of homozygotes: 0
population: European (Non-Finnish)
population: Other
population: East Asian
population: European (Finnish)
population: African
population: Latino
population: South Asian
reference allele: A
site quality: MQ
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: FS
site quality: MQRankSum
site quality: ClippingRankSum
site quality: DP
site quality: VQSLOD
site quality: QD
site quality: BaseQRankSum

1-46521524-A-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521524
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521524
    reference: chr 1
allele count: 2
allele frequency: 1.651200422707308e-5
allele num: 121124
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.884T>A
  hgvsp: ENSP00000262741.5:p.Met295Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1022T>A
  hgvsp: ENSP00000439913.1:p.Met341Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6077T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.884T>A
  hgvsp: ENSP00000412546.1:p.Met295Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1583T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.884T>A
  hgvsp: ENSP00000361075.1:p.Met295Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6077T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6077T>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 362
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23319
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2740
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 280
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1488
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1736
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2967
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1585
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 4139
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1495
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2550
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 120
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1886
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1484
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3323
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3244
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2159
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 679
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 94
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 87
  bin: 4.25e1
  variant carriers: 0
hgvs: p.Met295Lys
num of homozygotes: 0
population: European (Finnish)
population: East Asian
population: South Asian
population: European (Non-Finnish)
population: African
population: Other
population: Latino
reference allele: A
site quality: QD
site quality: FS
site quality: MQRankSum
site quality: MQ
site quality: VQSLOD
site quality: DP
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: BaseQRankSum

1-46521525-T-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521525
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521525
    reference: chr 1
allele count: 1
allele frequency: 8.256683785524381e-6
allele num: 121114
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.883A>T
  hgvsp: ENSP00000361075.1:p.Met295Leu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1021A>T
  hgvsp: ENSP00000439913.1:p.Met341Leu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.883A>T
  hgvsp: ENSP00000412546.1:p.Met295Leu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6076A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6076A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1582A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.883A>T
  hgvsp: ENSP00000262741.5:p.Met295Leu
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6076A>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 117
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1886
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3323
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23319
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2569
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1484
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4141
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1588
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1488
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2967
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 277
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 343
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2739
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1495
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3244
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1736
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 122
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 167
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49047
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 42
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 155
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Met295Leu
num of homozygotes: 0
population: African
population: East Asian
population: Latino
population: European (Finnish)
population: South Asian
population: European (Non-Finnish)
population: Other
reference allele: T
site quality: DP
site quality: InbreedingCoeff
site quality: FS
site quality: ClippingRankSum
site quality: BaseQRankSum
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: VQSLOD
site quality: MQ
site quality: QD

1-46521530-T-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521530
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521530
    reference: chr 1
allele count: 1
allele frequency: 8.251914444151043e-6
allele num: 121184
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6071A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6071A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6071A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.878A>C
  hgvsp: ENSP00000412546.1:p.Lys293Thr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1016A>C
  hgvsp: ENSP00000439913.1:p.Lys339Thr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.878A>C
  hgvsp: ENSP00000262741.5:p.Lys293Thr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1577A>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.878A>C
  hgvsp: ENSP00000361075.1:p.Lys293Thr
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4158
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 257
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1881
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2679
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23317
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3324
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1495
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2741
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1484
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3244
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2967
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1489
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 253
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1586
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1736
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 109
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1024
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5371
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1570
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 44
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 129
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 6
  bin: 1.75e1
  variant carriers: 0
hgvs: p.Lys293Thr
num of homozygotes: 0
population: East Asian
population: South Asian
population: African
population: Latino
population: European (Non-Finnish)
population: Other
population: European (Finnish)
reference allele: T
site quality: BaseQRankSum
site quality: DP
site quality: MQ
site quality: FS
site quality: MQRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: VQSLOD
site quality: ReadPosRankSum

1-46521532-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521532
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521532
    reference: chr 1
allele count: 134
allele frequency: 1.105647051057791e-3
allele num: 121196
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.876T>C
  hgvsp: ENST00000372006.1:c.876T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.876T>C
  hgvsp: ENST00000262741.5:c.876T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6069T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.876T>C
  hgvsp: ENST00000420542.1:c.876T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1575T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1014T>C
  hgvsp: ENST00000540385.1:c.1014T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6069T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6069T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2742
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 4159
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1496
  bin: 5.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1736
  bin: 6.25e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 23316
  bin: 9.75e1
  variant carriers: 93
genotype depth: GenotypeDepth
  all individuals: 2968
  bin: 7.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 1488
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 104
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3326
  bin: 8.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2735
  bin: 2.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 211
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2659
  bin: 7.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 244
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1485
  bin: 5.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 3242
  bin: 9.25e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 8.25e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 2161
  bin: 6.75e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 1883
  bin: 3.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 1585
  bin: 4.25e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 868
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1023
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 132
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 49059
  bin: 9.75e1
  variant carriers: 134
genotype quality: GenotypeQuality
  all individuals: 106
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1561
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Asp292Asp
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: African
population: Latino
population: Other
population: East Asian
population: South Asian
reference allele: A
site quality: MQRankSum
site quality: FS
site quality: MQ
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: QD
site quality: DP

1-46521533-T-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521533
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521533
    reference: chr 1
allele count: 1
allele frequency: 8.251233559417133e-6
allele num: 121194
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6068A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.875A>T
  hgvsp: ENSP00000361075.1:p.Asp292Val
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.875A>T
  hgvsp: ENSP00000262741.5:p.Asp292Val
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6068A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1013A>T
  hgvsp: ENSP00000439913.1:p.Asp338Val
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.875A>T
  hgvsp: ENSP00000412546.1:p.Asp292Val
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6068A>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1574A>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2739
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 203
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1881
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 105
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1743
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2760
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2972
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23285
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 4157
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2662
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1589
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 235
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3165
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1498
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1490
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1490
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3326
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3243
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2160
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 24
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 45
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 45
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 484
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 119
  bin: 2.25e1
  variant carriers: 0
hgvs: p.Asp292Val
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: African
population: East Asian
population: Latino
population: Other
population: South Asian
reference allele: T
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: FS
site quality: BaseQRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: DP
site quality: QD
site quality: MQRankSum
site quality: ClippingRankSum

1-46521533-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521533
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521533
    reference: chr 1
allele count: 2
allele frequency: 1.650246711883427e-5
allele num: 121194
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6068A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6068A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.875A>G
  hgvsp: ENSP00000361075.1:p.Asp292Gly
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1013A>G
  hgvsp: ENSP00000439913.1:p.Asp338Gly
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1574A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.875A>G
  hgvsp: ENSP00000262741.5:p.Asp292Gly
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.875A>G
  hgvsp: ENSP00000412546.1:p.Asp292Gly
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6068A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1589
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2739
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2160
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4157
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2662
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1490
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1743
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2760
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 203
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3165
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1490
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 105
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 235
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3326
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3243
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1881
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1498
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23285
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 2972
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 871
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 104
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 45
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1022
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 85
  bin: 4.75e1
  variant carriers: 0
hgvs: p.Asp292Gly
num of homozygotes: 0
population: African
population: East Asian
population: South Asian
population: Other
population: Latino
population: European (Non-Finnish)
population: European (Finnish)
reference allele: T
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: DP
site quality: QD
site quality: MQ
site quality: ClippingRankSum
site quality: FS
site quality: BaseQRankSum

1-46521543-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521543
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521543
    reference: chr 1
allele count: 18
allele frequency: 1.484829986966492e-4
allele num: 121226
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6058C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.1003C>T
  hgvsp: ENSP00000439913.1:p.Arg335Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6058C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.865C>T
  hgvsp: ENSP00000361075.1:p.Arg289Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1564C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6058C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.865C>T
  hgvsp: ENSP00000262741.5:p.Arg289Ter
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: stop_gained
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.865C>T
  hgvsp: ENSP00000412546.1:p.Arg289Ter
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: stop gained
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 147
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1743
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2951
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4175
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1490
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1872
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 123
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1491
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 89
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1498
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2161
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3326
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3164
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3243
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2661
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2725
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2973
  bin: 7.75e1
  variant carriers: 4
genotype depth: GenotypeDepth
  all individuals: 23285
  bin: 9.75e1
  variant carriers: 12
genotype depth: GenotypeDepth
  all individuals: 1588
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 80
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 971
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1037
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 488
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
hgvs: p.Arg289Ter
num of homozygotes: 0
population: European (Non-Finnish)
population: Latino
population: East Asian
population: African
population: European (Finnish)
population: South Asian
population: Other
reference allele: G
site quality: FS
site quality: QD
site quality: DP
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: MQ
site quality: VQSLOD
site quality: BaseQRankSum

http://identifiers.org/exac.variant/1-46521550-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521550
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521550
    reference: chr 1
allele count: 1
allele frequency: 8.247558722618106e-6
allele num: 121248
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6051G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6051G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1557G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.858G>T
  hgvsp: ENSP00000262741.5:p.Leu286Phe
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.858G>T
  hgvsp: ENSP00000412546.1:p.Leu286Phe
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.858G>T
  hgvsp: ENSP00000361075.1:p.Leu286Phe
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6051G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.996G>T
  hgvsp: ENSP00000439913.1:p.Leu332Phe
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 4183
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1868
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23279
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 125
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1745
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2996
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 119
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1490
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2662
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2969
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 76
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1589
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3328
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1498
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2714
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1491
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3164
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2163
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3246
  bin: 9.25e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 49054
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 74
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 36
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 875
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5551
  bin: 6.25e1
  variant carriers: 0
hgvs: p.Leu286Phe
num of homozygotes: 0
population: East Asian
population: Other
population: European (Non-Finnish)
population: African
population: Latino
population: South Asian
population: European (Finnish)
reference allele: C
site quality: InbreedingCoeff
site quality: FS
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: MQRankSum
site quality: QD
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: MQ
site quality: DP

1-46521559-A-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521559
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521559
    reference: chr 1
allele count: 84204
allele frequency: 6.940080771449765e-1
allele num: 121330
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6042T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6042T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.849T>A
  hgvsp: ENSP00000262741.5:p.Asn283Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1548T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.849T>A
  hgvsp: ENSP00000361075.1:p.Asn283Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.849T>A
  hgvsp: ENSP00000412546.1:p.Asn283Lys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6042T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.987T>A
  hgvsp: ENSP00000439913.1:p.Asn329Lys
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1673
  bin: 3.75e1
  variant carriers: 1362
genotype depth: GenotypeDepth
  all individuals: 1957
  bin: 4.75e1
  variant carriers: 1901
genotype depth: GenotypeDepth
  all individuals: 22710
  bin: 9.75e1
  variant carriers: 22682
genotype depth: GenotypeDepth
  all individuals: 27
  bin: 7.5e0
  variant carriers: 15
genotype depth: GenotypeDepth
  all individuals: 3163
  bin: 7.75e1
  variant carriers: 3154
genotype depth: GenotypeDepth
  all individuals: 3274
  bin: 9.25e1
  variant carriers: 3265
genotype depth: GenotypeDepth
  all individuals: 3299
  bin: 8.25e1
  variant carriers: 3288
genotype depth: GenotypeDepth
  all individuals: 2297
  bin: 3.25e1
  variant carriers: 1194
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 57
  bin: 1.25e1
  variant carriers: 53
genotype depth: GenotypeDepth
  all individuals: 3461
  bin: 8.75e1
  variant carriers: 3451
genotype depth: GenotypeDepth
  all individuals: 3384
  bin: 2.75e1
  variant carriers: 759
genotype depth: GenotypeDepth
  all individuals: 183
  bin: 1.75e1
  variant carriers: 178
genotype depth: GenotypeDepth
  all individuals: 1976
  bin: 5.25e1
  variant carriers: 1951
genotype depth: GenotypeDepth
  all individuals: 1861
  bin: 4.25e1
  variant carriers: 1739
genotype depth: GenotypeDepth
  all individuals: 2539
  bin: 6.75e1
  variant carriers: 2524
genotype depth: GenotypeDepth
  all individuals: 2874
  bin: 7.25e1
  variant carriers: 2864
genotype depth: GenotypeDepth
  all individuals: 2106
  bin: 6.25e1
  variant carriers: 2085
genotype depth: GenotypeDepth
  all individuals: 1876
  bin: 2.25e1
  variant carriers: 407
genotype depth: GenotypeDepth
  all individuals: 1988
  bin: 5.75e1
  variant carriers: 1960
genotype quality: GenotypeQuality
  all individuals: 27
  bin: 3.75e1
  variant carriers: 23
genotype quality: GenotypeQuality
  all individuals: 355
  bin: 9.25e1
  variant carriers: 299
genotype quality: GenotypeQuality
  all individuals: 8
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 19
  bin: 3.25e1
  variant carriers: 17
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 5.75e1
  variant carriers: 35
genotype quality: GenotypeQuality
  all individuals: 11
  bin: 2.75e1
  variant carriers: 7
genotype quality: GenotypeQuality
  all individuals: 22
  bin: 2.25e1
  variant carriers: 7
hgvs: p.Asn283Lys
num of homozygotes: 29390
population: Latino
population: South Asian
population: Other
population: African
population: European (Finnish)
population: European (Non-Finnish)
population: East Asian
reference allele: A
site quality: VQSLOD
site quality: ClippingRankSum
site quality: MQRankSum
site quality: QD
site quality: DP
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: FS
site quality: MQ
site quality: BaseQRankSum

http://identifiers.org/exac.variant/1-46521570-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521570
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521570
    reference: chr 1
allele count: 1
allele frequency: 8.257638315441784e-6
allele num: 121100
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.838G>T
  hgvsp: ENSP00000412546.1:p.Asp280Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.976G>T
  hgvsp: ENSP00000439913.1:p.Asp326Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1537G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6031G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6031G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.838G>T
  hgvsp: ENSP00000262741.5:p.Asp280Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.838G>T
  hgvsp: ENSP00000361075.1:p.Asp280Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6031G>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 206
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1233
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 111
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12917
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 186
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 83
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 164
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 166
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 152
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 512
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11354
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 29324
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3545
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 189
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 289
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 51
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 22
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 36
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2323
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 44
  bin: 4.75e1
  variant carriers: 0
hgvs: p.Asp280Tyr
num of homozygotes: 0
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: Latino
population: South Asian
population: East Asian
population: Other
reference allele: C
site quality: MQ
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: ClippingRankSum
site quality: QD
site quality: ReadPosRankSum
site quality: FS
site quality: DP
site quality: BaseQRankSum

1-46521570-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521570
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521570
    reference: chr 1
allele count: 13
allele frequency: 1.073492981007432e-4
allele num: 121100
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.838G>A
  hgvsp: ENSP00000262741.5:p.Asp280Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.976G>A
  hgvsp: ENSP00000439913.1:p.Asp326Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6031G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.838G>A
  hgvsp: ENSP00000361075.1:p.Asp280Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6031G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.838G>A
  hgvsp: ENSP00000412546.1:p.Asp280Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1537G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6031G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 111
  bin: 7.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 29324
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11354
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 83
  bin: 8.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 189
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 289
  bin: 5.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 1233
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 206
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 512
  bin: 4.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 152
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12917
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 51
  bin: 8.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 164
  bin: 6.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 186
  bin: 6.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 166
  bin: 9.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 3545
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 22
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 44
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 40732
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 36
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2340
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Asp280Asn
num of homozygotes: 0
population: European (Non-Finnish)
population: Other
population: South Asian
population: Latino
population: African
population: East Asian
population: European (Finnish)
reference allele: C
site quality: MQRankSum
site quality: ClippingRankSum
site quality: VQSLOD
site quality: BaseQRankSum
site quality: QD
site quality: MQ
site quality: ReadPosRankSum
site quality: FS
site quality: DP
site quality: InbreedingCoeff

1-46521579-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521579
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521579
    reference: chr 1
allele count: 2
allele frequency: 1.65371258475277e-5
allele num: 120940
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.967C>T
  hgvsp: ENST00000540385.1:c.967C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6022C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.829C>T
  hgvsp: ENST00000420542.1:c.829C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6022C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.829C>T
  hgvsp: ENST00000262741.5:c.829C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6022C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.829C>T
  hgvsp: ENST00000372006.1:c.829C>T(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1528C>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 206
  bin: 5.75e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 164
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 228
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 123
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12868
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 29214
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 268
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1231
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11373
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 183
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 161
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3536
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 510
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 286
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 531
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 86
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 650
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 65
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
hgvs: p.Leu277Leu
num of homozygotes: 0
population: European (Non-Finnish)
population: African
population: East Asian
population: South Asian
population: Latino
population: European (Finnish)
population: Other
reference allele: G
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: ClippingRankSum
site quality: FS
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: DP
site quality: MQ
site quality: BaseQRankSum
site quality: QD

1-46521581-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521581
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521581
    reference: chr 1
allele count: 1
allele frequency: 8.270477702792114e-6
allele num: 120912
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1526G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.827G>A
  hgvsp: ENSP00000262741.5:p.Arg276His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.827G>A
  hgvsp: ENSP00000412546.1:p.Arg276His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.965G>A
  hgvsp: ENSP00000439913.1:p.Arg322His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6020G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6020G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.827G>A
  hgvsp: ENSP00000361075.1:p.Arg276His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6020G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3531
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 164
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 204
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11394
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 29192
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 509
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12865
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 286
  bin: 5.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 118
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1228
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 278
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 238
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 183
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 161
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 649
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 43
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2858
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 40
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 67
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1688
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2293
  bin: 9.75e1
  variant carriers: 1
hgvs: p.Arg276His
num of homozygotes: 0
population: Latino
population: European (Finnish)
population: Other
population: European (Non-Finnish)
population: African
population: East Asian
population: South Asian
reference allele: C
site quality: DP
site quality: ClippingRankSum
site quality: MQRankSum
site quality: FS
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: MQ
site quality: QD
site quality: InbreedingCoeff
site quality: BaseQRankSum

1-46521582-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521582
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521582
    reference: chr 1
allele count: 1
allele frequency: 8.273351534706709e-6
allele num: 120870
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.964C>T
  hgvsp: ENSP00000439913.1:p.Arg322Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.826C>T
  hgvsp: ENSP00000412546.1:p.Arg276Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.826C>T
  hgvsp: ENSP00000262741.5:p.Arg276Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.826C>T
  hgvsp: ENSP00000361075.1:p.Arg276Cys
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6019C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6019C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6019C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1525C>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 12849
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 164
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11377
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 183
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 29200
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 505
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 293
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 285
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 122
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1232
  bin: 4.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 247
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 205
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 160
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3529
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 29
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 445
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 40640
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 525
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 45
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Arg276Cys
num of homozygotes: 0
population: European (Finnish)
population: East Asian
population: South Asian
population: African
population: European (Non-Finnish)
population: Latino
population: Other
reference allele: G
site quality: QD
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: VQSLOD
site quality: MQ
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: FS
site quality: DP

1-46521597-G-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521597
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521597
    reference: chr 1
allele count: 1
allele frequency: 8.309512730173502e-6
allele num: 120344
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+6004C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.811C>G
  hgvsp: ENSP00000361075.1:p.His271Asp
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.811C>G
  hgvsp: ENSP00000412546.1:p.His271Asp
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+6004C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1510C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+6004C>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.811C>G
  hgvsp: ENSP00000262741.5:p.His271Asp
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.949C>G
  hgvsp: ENSP00000439913.1:p.His317Asp
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 28907
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 667
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12676
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 201
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11194
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 512
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 281
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1217
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 39
  bin: 9.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3507
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 503
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 175
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2257
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 14
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 120
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1645
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 56
  bin: 5.25e1
  variant carriers: 0
hgvs: p.His271Asp
num of homozygotes: 0
population: Latino
population: East Asian
population: Other
population: South Asian
population: African
population: European (Non-Finnish)
population: European (Finnish)
reference allele: G
site quality: ReadPosRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: ClippingRankSum
site quality: MQRankSum
site quality: BaseQRankSum
site quality: FS
site quality: QD
site quality: MQ

1-46521611-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521611
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521611
    reference: chr 1
allele count: 2
allele frequency: 1.697965836927361e-5
allele num: 117788
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.797G>A
  hgvsp: ENSP00000262741.5:p.Arg266His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5990G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.797G>A
  hgvsp: ENSP00000361075.1:p.Arg266His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5990G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5990G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.797G>A
  hgvsp: ENSP00000412546.1:p.Arg266His
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1496G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.935G>A
  hgvsp: ENSP00000439913.1:p.Arg312His
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10689
  bin: 2.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 2045
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 563
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 201
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 277
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 27440
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 44
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11854
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1721
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3340
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1182
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 494
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 15
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 515
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 39
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 18
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8345
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 143
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 173
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Arg266His
num of homozygotes: 0
population: Latino
population: Other
population: South Asian
population: European (Non-Finnish)
population: African
population: East Asian
population: European (Finnish)
reference allele: C
site quality: MQRankSum
site quality: QD
site quality: FS
site quality: MQ
site quality: VQSLOD
site quality: BaseQRankSum
site quality: DP
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: ReadPosRankSum

1-46521621-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521621
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521621
    reference: chr 1
allele count: 1
allele frequency: 8.785030308354564e-6
allele num: 113830
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5980T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5980T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.787T>C
  hgvsp: ENST00000420542.1:c.787T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1486T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.787T>C
  hgvsp: ENST00000262741.5:c.787T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.787T>C
  hgvsp: ENST00000372006.1:c.787T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.925T>C
  hgvsp: ENST00000540385.1:c.925T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5980T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 125
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10388
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3071
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 275
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3601
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1142
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 200
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10304
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 159
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1054
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4073
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25130
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 487
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 913
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 163
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 375
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34210
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 152
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 268
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 115
  bin: 1.75e1
  variant carriers: 0
hgvs: p.Leu263Leu
num of homozygotes: 0
population: Latino
population: East Asian
population: African
population: European (Non-Finnish)
population: Other
population: European (Finnish)
population: South Asian
reference allele: A
site quality: VQSLOD
site quality: MQ
site quality: FS
site quality: ReadPosRankSum
site quality: DP
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: MQRankSum
site quality: QD

1-46521625-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521625
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521625
    reference: chr 1
allele count: 1
allele frequency: 9.169432778888298e-6
allele num: 109058
alternate allele: G
annotation: Annotation
  canonical: true
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.783T>C
  hgvsp: ENST00000262741.5:c.783T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5976T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.783T>C
  hgvsp: ENST00000372006.1:c.783T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1482T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.921T>C
  hgvsp: ENST00000540385.1:c.921T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5976T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5976T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: synonymous_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.783T>C
  hgvsp: ENST00000420542.1:c.783T>C(p.%3D)
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: synonymous
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 6547
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10894
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 23835
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 76
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5610
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 197
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 693
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1530
  bin: 1.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 247
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 256
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7943
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 158
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1698
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 398
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 485
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 31041
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1054
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 212
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1976
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 563
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 747
  bin: 3.75e1
  variant carriers: 0
hgvs: p.Asp261Asp
num of homozygotes: 0
population: European (Non-Finnish)
population: East Asian
population: Latino
population: Other
population: South Asian
population: African
population: European (Finnish)
reference allele: A
site quality: FS
site quality: MQ
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: DP
site quality: VQSLOD
site quality: MQRankSum
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: QD

http://identifiers.org/exac.variant/1-46521627-C-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521627
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521627
    reference: chr 1
allele count: 1
allele frequency: 9.178353770467728e-6
allele num: 108952
alternate allele: A
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.919G>T
  hgvsp: ENSP00000439913.1:p.Asp307Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.781G>T
  hgvsp: ENSP00000262741.5:p.Asp261Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5974G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5974G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1480G>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.781G>T
  hgvsp: ENSP00000412546.1:p.Asp261Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.781G>T
  hgvsp: ENSP00000361075.1:p.Asp261Tyr
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5974G>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1498
  bin: 1.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 7675
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 380
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24123
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6525
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 621
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 196
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 252
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5668
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11172
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1487
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 76
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 158
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 884
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1506
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 9280
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1304
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 305
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 953
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 337
  bin: 7.5e0
  variant carriers: 0
hgvs: p.Asp261Tyr
num of homozygotes: 0
population: African
population: South Asian
population: European (Finnish)
population: Other
population: East Asian
population: Latino
population: European (Non-Finnish)
reference allele: C
site quality: FS
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: MQ
site quality: DP
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: QD
site quality: ClippingRankSum

1-46521627-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521627
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521627
    reference: chr 1
allele count: 1
allele frequency: 9.178353770467728e-6
allele num: 108952
alternate allele: T
annotation: Annotation
  canonical: true
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.781G>A
  hgvsp: ENSP00000262741.5:p.Asp261Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5974G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.781G>A
  hgvsp: ENSP00000412546.1:p.Asp261Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.781G>A
  hgvsp: ENSP00000361075.1:p.Asp261Asn
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5974G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5974G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1480G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: missense_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.919G>A
  hgvsp: ENSP00000439913.1:p.Asp307Asn
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: missense
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 11172
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 621
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 6525
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1487
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 158
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 24123
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 196
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 7675
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1498
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 76
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 252
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 380
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5668
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1304
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 376
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2454
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 337
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 154
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2047
  bin: 9.75e1
  variant carriers: 1
genotype quality: GenotypeQuality
  all individuals: 4776
  bin: 6.75e1
  variant carriers: 0
hgvs: p.Asp261Asn
num of homozygotes: 0
population: Latino
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: Other
population: East Asian
population: South Asian
reference allele: C
site quality: MQ
site quality: MQRankSum
site quality: DP
site quality: ReadPosRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: FS
site quality: BaseQRankSum
site quality: ClippingRankSum

1-46521646-G-A
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521646
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521646
    reference: chr 1
allele count: 2
allele frequency: 1.926930784646216e-5
allele num: 103792
alternate allele: A
annotation: Annotation
  canonical: true
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.765-3C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.903-3C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5955C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.765-3C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1461C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5955C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: splice_region_variant
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.765-3C>T
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5955C>T
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: splice region
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 158
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12122
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 9846
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8163
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4847
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 506
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 20404
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 935
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 527
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1683
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 368
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2159
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 575
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 57
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 195
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2245
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 300
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 13638
  bin: 2.25e1
  variant carriers: 0
hgvs: c.765-3C>T
num of homozygotes: 0
population: African
population: European (Finnish)
population: South Asian
population: Latino
population: Other
population: European (Non-Finnish)
population: East Asian
reference allele: G
site quality: ClippingRankSum
site quality: DP
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: QD
site quality: VQSLOD
site quality: BaseQRankSum
site quality: InbreedingCoeff
site quality: FS
site quality: MQ

1-46521654-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521654
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521654
    reference: chr 1
allele count: 1
allele frequency: 1.002827974889188e-5
allele num: 99718
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1453T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.765-11T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5947T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.765-11T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5947T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.903-11T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.765-11T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5947T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: false
consequence: non coding transcript exon
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 9847
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3614
  bin: 3.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 870
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 862
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 10755
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2509
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 367
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 14088
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 158
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 518
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15965
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 917
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 799
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 291
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 16878
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3601
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 245
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3269
  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 512
  bin: 8.25e1
  variant carriers: 0
num of homozygotes: 0
population: South Asian
population: Latino
population: African
population: East Asian
population: European (Non-Finnish)
population: European (Finnish)
population: Other
reference allele: A
site quality: DP
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: MQ
site quality: QD
site quality: FS
site quality: VQSLOD
site quality: MQRankSum
site quality: ReadPosRankSum
site quality: ClippingRankSum

1-46521676-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521676
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521676
    reference: chr 1
allele count: 1
allele frequency: 1.095890410958904e-5
allele num: 91250
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1431A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.765-33A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.903-33A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.765-33A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5925A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.765-33A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5925A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5925A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: false
consequence: non coding transcript exon
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5696
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 8734
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 157
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 504
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12260
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2490
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 22103
  bin: 1.25e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 735
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1402
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 362
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5060
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1322
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 576
  bin: 7.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 187
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1156
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 414
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1218
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1194
  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 18997
  bin: 2.25e1
  variant carriers: 0
num of homozygotes: 0
population: Latino
population: European (Finnish)
population: South Asian
population: African
population: East Asian
population: European (Non-Finnish)
population: Other
reference allele: T
site quality: ReadPosRankSum
site quality: ClippingRankSum
site quality: InbreedingCoeff
site quality: QD
site quality: DP
site quality: FS
site quality: BaseQRankSum
site quality: MQ
site quality: MQRankSum
site quality: VQSLOD

1-46521682-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521682
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521682
    reference: chr 1
allele count: 20
allele frequency: 2.257591150242691e-4
allele num: 88590
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5919A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5919A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1425A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.765-39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.765-39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5919A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.903-39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.765-39A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: false
consequence: non coding transcript exon
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 503
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 157
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 3429
  bin: 2.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 1235
  bin: 3.25e1
  variant carriers: 2
genotype depth: GenotypeDepth
  all individuals: 4150
  bin: 2.25e1
  variant carriers: 6
genotype depth: GenotypeDepth
  all individuals: 13203
  bin: 7.5e0
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 725
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 362
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 21359
  bin: 1.25e1
  variant carriers: 8
genotype depth: GenotypeDepth
  all individuals: 2749
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 11607
  bin: 1.75e1
  variant carriers: 3
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2065
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 251
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5965
  bin: 6.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 5961
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 207
  bin: 5.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 551
  bin: 7.75e1
  variant carriers: 2
genotype quality: GenotypeQuality
  all individuals: 442
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3133
  bin: 7.5e0
  variant carriers: 0
num of homozygotes: 0
population: Latino
population: European (Non-Finnish)
population: African
population: European (Finnish)
population: Other
population: South Asian
population: East Asian
reference allele: T
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: MQRankSum
site quality: MQ
site quality: ClippingRankSum
site quality: QD
site quality: FS
site quality: VQSLOD
site quality: ReadPosRankSum
site quality: DP

1-46521690-A-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521690
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521690
    reference: chr 1
allele count: 1
allele frequency: 1.175751305083949e-5
allele num: 85052
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1417T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5911T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.765-47T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.903-47T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5911T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.765-47T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.765-47T>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5911T>A
  variant of: http://identifiers.org/hgnc/8981
canonical: false
consequence: non coding transcript exon
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 721
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2822
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4630
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 20107
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2103
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 500
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 195
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 157
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 14784
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12162
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1089
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 14584
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 8502
  bin: 3.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 426
  bin: 8.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1349
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 369
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 4129
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 183
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 411
  bin: 2.5e0
  variant carriers: 0
num of homozygotes: 0
population: Other
population: African
population: South Asian
population: East Asian
population: European (Non-Finnish)
population: Latino
population: European (Finnish)
reference allele: A
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: MQ
site quality: DP
site quality: FS
site quality: ReadPosRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: MQRankSum
site quality: VQSLOD

1-46521695-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46521695
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46521695
    reference: chr 1
allele count: 1
allele frequency: 1.21097628908426e-5
allele num: 82578
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+5906A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.765-52A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: non_coding_transcript_variant
  consequence: non_coding_transcript_exon_variant
  ensembl gene: ENSG00000117461
  ensembl transcript: ENST00000488808
  gene symbol: PIK3R3
  hgvsc: ENST00000488808.1:n.1412A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.765-52A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.903-52A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+5906A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+5906A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.765-52A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: false
consequence: non coding transcript exon
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 360
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 157
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 82
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1942
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 48
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1059
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4822
  bin: 2.25e1
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genotype depth: GenotypeDepth
  all individuals: 195
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 163
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 251
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 109
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 12078
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 719
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2826
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 19903
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  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 38
  bin: 9.25e1
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genotype depth: GenotypeDepth
  all individuals: 75
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 499
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 15056
  bin: 7.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2156
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 183
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 11477
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1538
  bin: 6.25e1
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genotype quality: GenotypeQuality
  all individuals: 2789
  bin: 1.25e1
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genotype quality: GenotypeQuality
  all individuals: 355
  bin: 7.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 3361
  bin: 4.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 7096
  bin: 1.75e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: African
population: South Asian
population: Other
population: European (Non-Finnish)
population: East Asian
population: Latino
reference allele: T
site quality: MQRankSum
site quality: BaseQRankSum
site quality: MQ
site quality: InbreedingCoeff
site quality: ClippingRankSum
site quality: QD
site quality: VQSLOD
site quality: FS
site quality: DP
site quality: ReadPosRankSum

1-46527555-G-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527555
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527555
    reference: chr 1
allele count: 1
allele frequency: 8.236553825879253e-6
allele num: 121410
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+46C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+46C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+46C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+46C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+46C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+46C>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+46C>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5313
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 405
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2078
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 509
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 153
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1370
  bin: 9.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 677
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25537
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 300
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 213
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 181
  bin: 8.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 18058
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 277
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4349
  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10258
  bin: 6.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34537
  bin: 6.25e1
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genotype quality: GenotypeQuality
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  bin: 8.25e1
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genotype quality: GenotypeQuality
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  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
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  variant carriers: 0
genotype quality: GenotypeQuality
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  variant carriers: 0
genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
num of homozygotes: 0
population: South Asian
population: Latino
population: African
population: Other
population: East Asian
population: European (Finnish)
population: European (Non-Finnish)
reference allele: G
site quality: ReadPosRankSum
site quality: MQ
site quality: MQRankSum
site quality: VQSLOD
site quality: FS
site quality: DP
site quality: InbreedingCoeff
site quality: QD
site quality: BaseQRankSum
site quality: ClippingRankSum

1-46527562-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527562
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527562
    reference: chr 1
allele count: 1
allele frequency: 8.236553825879253e-6
allele num: 121410
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+39A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+39A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 25538
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2078
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
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genotype depth: GenotypeDepth
  all individuals: 5312
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genotype depth: GenotypeDepth
  all individuals: 4353
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18059
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
  all individuals: 153
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genotype quality: GenotypeQuality
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  variant carriers: 0
genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
  all individuals: 34545
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genotype quality: GenotypeQuality
  all individuals: 0
  bin: 4.25e1
  variant carriers: 0
num of homozygotes: 0
population: South Asian
population: Other
population: European (Non-Finnish)
population: European (Finnish)
population: Latino
population: African
population: East Asian
reference allele: T
site quality: ReadPosRankSum
site quality: DP
site quality: ClippingRankSum
site quality: QD
site quality: BaseQRankSum
site quality: MQ
site quality: FS
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: MQRankSum

1-46527567-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527567
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527567
    reference: chr 1
allele count: 1
allele frequency: 8.236689509752241e-6
allele num: 121408
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+34G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+34G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+34G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+34G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+34G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+34G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+34G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18059
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 677
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  variant carriers: 0
genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5313
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 509
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 213
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1369
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  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 153
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25538
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 276
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2078
  bin: 4.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 3.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
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  bin: 2.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
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  bin: 2.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2046
  bin: 8.25e1
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genotype quality: GenotypeQuality
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  bin: 7.25e1
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genotype quality: GenotypeQuality
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  bin: 1.75e1
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genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1162
  bin: 9.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34545
  bin: 6.25e1
  variant carriers: 0
num of homozygotes: 0
population: South Asian
population: African
population: European (Finnish)
population: Latino
population: European (Non-Finnish)
population: Other
population: East Asian
reference allele: C
site quality: QD
site quality: VQSLOD
site quality: BaseQRankSum
site quality: MQ
site quality: FS
site quality: DP
site quality: InbreedingCoeff
site quality: ReadPosRankSum
site quality: MQRankSum
site quality: ClippingRankSum

1-46527569-C-T
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527569
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527569
    reference: chr 1
allele count: 4
allele frequency: 3.294621530351701e-5
allele num: 121410
alternate allele: T
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+32G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+32G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+32G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+32G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+32G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+32G>A
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+32G>A
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 4353
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 153
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18059
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 1.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2078
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 276
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 677
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 213
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 509
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 405
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25538
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 301
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5314
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 8.25e1
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genotype depth: GenotypeDepth
  all individuals: 180
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1368
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  variant carriers: 4
genotype quality: GenotypeQuality
  all individuals: 6271
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  variant carriers: 4
genotype quality: GenotypeQuality
  all individuals: 10259
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  variant carriers: 0
genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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  bin: 1.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34545
  bin: 6.25e1
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genotype quality: GenotypeQuality
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  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 2549
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
  all individuals: 2046
  bin: 8.25e1
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genotype quality: GenotypeQuality
  all individuals: 0
  bin: 4.25e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: South Asian
population: Latino
population: African
population: East Asian
population: Other
reference allele: C
site quality: VQSLOD
site quality: InbreedingCoeff
site quality: DP
site quality: MQRankSum
site quality: ClippingRankSum
site quality: QD
site quality: BaseQRankSum
site quality: MQ
site quality: FS
site quality: ReadPosRankSum

1-46527588-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527588
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527588
    reference: chr 1
allele count: 1
allele frequency: 8.236553825879253e-6
allele num: 121410
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+13A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+13A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+13A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+13A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+13A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+13A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+13A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 2079
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 153
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 18059
  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5313
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 677
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 510
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1
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  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1365
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 25541
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 405
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4352
  bin: 2.25e1
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genotype depth: GenotypeDepth
  all individuals: 276
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 301
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genotype depth: GenotypeDepth
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  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 213
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 8.25e1
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genotype quality: GenotypeQuality
  all individuals: 0
  bin: 2.5e0
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 1
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  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 34546
  bin: 6.25e1
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genotype quality: GenotypeQuality
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  bin: 7.25e1
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
  all individuals: 3071
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genotype quality: GenotypeQuality
  all individuals: 1
  bin: 2.25e1
  variant carriers: 0
num of homozygotes: 0
population: European (Finnish)
population: European (Non-Finnish)
population: East Asian
population: Other
population: Latino
population: South Asian
population: African
reference allele: T
site quality: MQ
site quality: FS
site quality: MQRankSum
site quality: BaseQRankSum
site quality: ClippingRankSum
site quality: ReadPosRankSum
site quality: QD
site quality: InbreedingCoeff
site quality: VQSLOD
site quality: DP

1-46527589-A-G
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527589
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527589
    reference: chr 1
allele count: 3
allele frequency: 2.471006852925672e-5
allele num: 121408
alternate allele: G
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+12T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+12T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+12T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+12T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+12T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+12T>C
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+12T>C
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 7.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 4352
  bin: 2.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25541
  bin: 2.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 677
  bin: 5.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 3.25e1
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genotype depth: GenotypeDepth
  all individuals: 1364
  bin: 9.75e1
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genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 405
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
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genotype depth: GenotypeDepth
  all individuals: 510
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genotype quality: GenotypeQuality
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  bin: 7.25e1
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genotype quality: GenotypeQuality
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  bin: 7.75e1
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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genotype quality: GenotypeQuality
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  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.25e1
  variant carriers: 0
num of homozygotes: 0
population: European (Non-Finnish)
population: European (Finnish)
population: African
population: South Asian
population: Other
population: Latino
population: East Asian
reference allele: A
site quality: ReadPosRankSum
site quality: DP
site quality: QD
site quality: InbreedingCoeff
site quality: BaseQRankSum
site quality: VQSLOD
site quality: MQ
site quality: FS
site quality: ClippingRankSum
site quality: MQRankSum

1-46527592-T-C
type: Variant
location: Region
  begin: Position
    type: ExactPosition
    position: 46527592
    reference: chr 1
  end: Position
    type: ExactPosition
    position: 46527592
    reference: chr 1
allele count: 1
allele frequency: 8.236553825879253e-6
allele num: 121410
alternate allele: C
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000342484
  ensembl transcript: ENST00000340332
  gene symbol: PIK3R3
  hgvsc: ENST00000340332.6:c.656+9A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000346188
  ensembl transcript: ENST00000354242
  gene symbol: PIK3R3
  hgvsc: ENST00000354242.4:c.764+9A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000361075
  ensembl transcript: ENST00000372006
  gene symbol: PIK3R3
  hgvsc: ENST00000372006.1:c.764+9A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000439913
  ensembl transcript: ENST00000540385
  gene symbol: PIK3R3
  hgvsc: ENST00000540385.1:c.902+9A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: true
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000262741
  ensembl transcript: ENST00000262741
  gene symbol: PIK3R3
  hgvsc: ENST00000262741.5:c.764+9A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000412546
  ensembl transcript: ENST00000420542
  gene symbol: PIK3R3
  hgvsc: ENST00000420542.1:c.764+9A>G
  variant of: http://identifiers.org/hgnc/8981
annotation: Annotation
  canonical: false
  consequence: intron_variant
  ensembl gene: ENSG00000117461
  ensembl protein: ENSP00000391431
  ensembl transcript: ENST00000423209
  gene symbol: PIK3R3
  hgvsc: ENST00000423209.1:c.764+9A>G
  variant of: http://identifiers.org/hgnc/8981
canonical: true
consequence: intron
filter: PASS
genotype depth: GenotypeDepth
  all individuals: 1
  bin: 2.5e0
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 2079
  bin: 4.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 405
  bin: 6.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
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  bin: 2.25e1
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genotype depth: GenotypeDepth
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  bin: 3.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 178
  bin: 8.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 25541
  bin: 2.75e1
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genotype depth: GenotypeDepth
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  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 301
  bin: 6.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 5314
  bin: 3.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 180
  bin: 8.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 276
  bin: 7.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1102
  bin: 4.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 213
  bin: 7.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 153
  bin: 9.25e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 1361
  bin: 9.75e1
  variant carriers: 1
genotype depth: GenotypeDepth
  all individuals: 510
  bin: 5.75e1
  variant carriers: 0
genotype depth: GenotypeDepth
  all individuals: 677
  bin: 5.25e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 801
  bin: 8.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 0
  bin: 1.75e1
  variant carriers: 0
genotype quality: GenotypeQuality
  all individuals: 10260
  bin: 6.75e1
  variant carriers: 0
num of homozygotes: 0
reference allele: T

GenotypeQuality
all individuals: 99
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 10
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 7355
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2066
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 33433
bin: 9.75e1
variant carriers: 3

GenotypeQuality
all individuals: 11
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 3720
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 142
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 191
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3623
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3544
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 79
bin: 5.25e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16428
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10404
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11564
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 3
allele frequency: 4.50220608097968e-5
allele num: 66634
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: -1.669e0

FS
type: SiteQuality
SIO_000300: 8.503e0

VQSLOD
type: SiteQuality
SIO_000300: 1.14e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 7.96e-1

DP
type: SiteQuality
SIO_000300: 2.892332e6

MQ
type: SiteQuality
SIO_000300: 5.202e1

MQRankSum
type: SiteQuality
SIO_000300: -5.411e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 0.0e0

QD
type: SiteQuality
SIO_000300: 9.18e0

BaseQRankSum
type: SiteQuality
SIO_000300: -1.803e0

GenotypeQuality
all individuals: 124
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 170
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 77
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 33459
bin: 9.75e1
variant carriers: 167

GenotypeQuality
all individuals: 6
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 215
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2075
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 146
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 92
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 7390
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3541
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 9
bin: 7.5e0
variant carriers: 0

African
type: Population
allele count: 3
allele frequency: 2.884060757546626e-4
allele num: 10402
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8638
num of homozygotes: 0

Other
type: Population
allele count: 2
allele frequency: 2.207505518763797e-3
allele num: 906
num of homozygotes: 0

Latino
type: Population
allele count: 38
allele frequency: 3.286628610966961e-3
allele num: 11562
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 113
allele frequency: 1.695983670528907e-3
allele num: 66628
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 5
allele frequency: 7.564296520423601e-4
allele num: 6610
num of homozygotes: 0

South Asian
type: Population
allele count: 6
allele frequency: 3.648747263439553e-4
allele num: 16444
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: 3.43e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 7.17e-1

MQ
type: SiteQuality
SIO_000300: 5.979e1

BaseQRankSum
type: SiteQuality
SIO_000300: 4.3e0

FS
type: SiteQuality
SIO_000300: 0.0e0

ClippingRankSum
type: SiteQuality
SIO_000300: -2.01e-1

DP
type: SiteQuality
SIO_000300: 2.895186e6

VQSLOD
type: SiteQuality
SIO_000300: 5.36e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -1.8e-3

QD
type: SiteQuality
SIO_000300: 1.565e1

GenotypeQuality
all individuals: 52
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 8
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 115
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 7
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 71
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 53
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2062
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 8
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 29
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 33390
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 3809
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3732
bin: 9.25e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11564
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16450
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8648
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.500510173458976e-5
allele num: 66644
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10402
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: -4.35e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 9.73e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.444e0

FS
type: SiteQuality
SIO_000300: 4.079e0

VQSLOD
type: SiteQuality
SIO_000300: -1.511e0

DP
type: SiteQuality
SIO_000300: 2.896316e6

BaseQRankSum
type: SiteQuality
SIO_000300: -4.58e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -4.0e-4

QD
type: SiteQuality
SIO_000300: 1.011e1

MQ
type: SiteQuality
SIO_000300: 5.861e1

GenotypeQuality
all individuals: 1
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 20
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 69
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 20
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 53
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3558
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 33392
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 21
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2084
bin: 8.75e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66664
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11572
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.06501698204755e-5
allele num: 16488
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10404
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 6.04e1

MQRankSum
type: SiteQuality
SIO_000300: 1.67e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -4.8e-1

FS
type: SiteQuality
SIO_000300: 8.96e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 8.090000000000001e-1

QD
type: SiteQuality
SIO_000300: 1.425e1

DP
type: SiteQuality
SIO_000300: 2.899165e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 2.4e0

BaseQRankSum
type: SiteQuality
SIO_000300: 3.39e0

GenotypeQuality
all individuals: 24
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 47
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 15
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 12
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 12
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3824
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3731
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3620
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 8224
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3561
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 24
bin: 2.75e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66680
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10404
num of homozygotes: 0

South Asian
type: Population
allele count: 3
allele frequency: 1.818402230573403e-4
allele num: 16498
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

BaseQRankSum
type: SiteQuality
SIO_000300: 3.52e0

FS
type: SiteQuality
SIO_000300: 5.36e0

MQ
type: SiteQuality
SIO_000300: 5.965e1

DP
type: SiteQuality
SIO_000300: 2.900243e6

VQSLOD
type: SiteQuality
SIO_000300: 6.03e-1

MQRankSum
type: SiteQuality
SIO_000300: -5.35e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: -1.04e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 2.9e-1

QD
type: SiteQuality
SIO_000300: 1.064e1

GenotypeQuality
all individuals: 3568
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 5
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 8
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 5
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 26
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 6
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2074
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 33392
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 3731
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3837
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 6
bin: 3.75e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66710
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.609840476648087e-5
allele num: 10406
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11578
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16510
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.05e-2

MQ
type: SiteQuality
SIO_000300: 6.0e1

DP
type: SiteQuality
SIO_000300: 2.90154e6

QD
type: SiteQuality
SIO_000300: 1.474e1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.75e0

VQSLOD
type: SiteQuality
SIO_000300: 1.6e0

MQRankSum
type: SiteQuality
SIO_000300: 5.25e-1

FS
type: SiteQuality
SIO_000300: 5.423e0

ClippingRankSum
type: SiteQuality
SIO_000300: -2.85e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 8.23e-1

GenotypeQuality
all individuals: 0
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 3731
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 8363
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2085
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3838
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3565
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 33392
bin: 9.75e1
variant carriers: 3

GenotypeQuality
all individuals: 3617
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2
bin: 4.75e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10406
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 3
allele frequency: 4.496537665997182e-5
allele num: 66718
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16510
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11578
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.968e1

MQRankSum
type: SiteQuality
SIO_000300: 1.1e-2

ClippingRankSum
type: SiteQuality
SIO_000300: -5.99e-1

VQSLOD
type: SiteQuality
SIO_000300: 2.3e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

FS
type: SiteQuality
SIO_000300: 1.17e0

DP
type: SiteQuality
SIO_000300: 2.901981e6

BaseQRankSum
type: SiteQuality
SIO_000300: -1.07e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 7.64e-1

QD
type: SiteQuality
SIO_000300: 1.341e1

GenotypeQuality
all individuals: 3
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 6
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3839
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 33391
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 3
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 13
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3731
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2074
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 8365
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3566
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 3618
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2085
bin: 8.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.498756032493031e-5
allele num: 66722
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11578
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10406
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16512
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.972e1

QD
type: SiteQuality
SIO_000300: 1.468e1

DP
type: SiteQuality
SIO_000300: 2.901918e6

VQSLOD
type: SiteQuality
SIO_000300: 3.41e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.149e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.49e0

MQRankSum
type: SiteQuality
SIO_000300: 1.28e0

FS
type: SiteQuality
SIO_000300: 1.124e0

BaseQRankSum
type: SiteQuality
SIO_000300: -5.765e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

GenotypeQuality
all individuals: 0
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2084
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 13
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 3617
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 33393
bin: 9.75e1
variant carriers: 5

GenotypeQuality
all individuals: 2
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3840
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 0
bin: 7.5e0
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11578
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
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European (Non-Finnish)
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allele count: 3
allele frequency: 4.49599856128046e-5
allele num: 66726
num of homozygotes: 0

European (Finnish)
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allele count: 2
allele frequency: 3.024803387779795e-4
allele num: 6612
num of homozygotes: 0

Other
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allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
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East Asian
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allele frequency: 0.0e0
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QD
type: SiteQuality
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FS
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SIO_000300: 1.107e0

BaseQRankSum
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SIO_000300: 6.54e-1

MQRankSum
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DP
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MQ
type: SiteQuality
SIO_000300: 5.945e1

VQSLOD
type: SiteQuality
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ClippingRankSum
type: SiteQuality
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InbreedingCoeff
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
SIO_000300: -4.23e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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Other
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allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 16512
num of homozygotes: 0

European (Non-Finnish)
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allele count: 5
allele frequency: 7.494004796163069e-5
allele num: 66720
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8654
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Latino
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allele frequency: 0.0e0
allele num: 11578
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African
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allele count: 0
allele frequency: 0.0e0
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InbreedingCoeff
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VQSLOD
type: SiteQuality
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FS
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BaseQRankSum
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ClippingRankSum
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QD
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MQRankSum
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DP
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ReadPosRankSum
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MQ
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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Latino
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allele frequency: 0.0e0
allele num: 11578
num of homozygotes: 0

African
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allele frequency: 9.611687812379854e-5
allele num: 10404
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South Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 16510
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European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66722
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6612
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East Asian
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Other
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InbreedingCoeff
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ClippingRankSum
type: SiteQuality
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FS
type: SiteQuality
SIO_000300: 9.09e-1

MQRankSum
type: SiteQuality
SIO_000300: -5.95e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.81e0

VQSLOD
type: SiteQuality
SIO_000300: 4.93e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -8.110000000000001e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

QD
type: SiteQuality
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DP
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
type: Population
allele count: 1
allele frequency: 1.512401693889897e-4
allele num: 6612
num of homozygotes: 0

South Asian
type: Population
allele count: 3
allele frequency: 1.816860465116279e-4
allele num: 16512
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 118
allele frequency: 1.768532118341776e-3
allele num: 66722
num of homozygotes: 1

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

African
type: Population
allele count: 5
allele frequency: 4.805843906189927e-4
allele num: 10404
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

Latino
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allele count: 11
allele frequency: 9.500777336327518e-4
allele num: 11578
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: -9.2e-2

FS
type: SiteQuality
SIO_000300: 5.2e-1

MQ
type: SiteQuality
SIO_000300: 5.968e1

DP
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InbreedingCoeff
type: SiteQuality
SIO_000300: 6.8e-3

ReadPosRankSum
type: SiteQuality
SIO_000300: 7.56e-1

QD
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SIO_000300: 1.26e1

ClippingRankSum
type: SiteQuality
SIO_000300: -3.48e-1

VQSLOD
type: SiteQuality
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MQRankSum
type: SiteQuality
SIO_000300: 2.33e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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East Asian
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allele count: 112
allele frequency: 1.294498381877023e-2
allele num: 8652
num of homozygotes: 0

South Asian
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allele count: 5
allele frequency: 3.028467595396729e-4
allele num: 16510
num of homozygotes: 0

Other
type: Population
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allele frequency: 0.0e0
allele num: 908
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

African
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allele count: 1
allele frequency: 9.613535858488752e-5
allele num: 10402
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European (Non-Finnish)
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allele count: 2
allele frequency: 2.998141152485459e-5
allele num: 66708
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
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MQ
type: SiteQuality
SIO_000300: 5.966e1

FS
type: SiteQuality
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ClippingRankSum
type: SiteQuality
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InbreedingCoeff
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SIO_000300: -9.0e-4

VQSLOD
type: SiteQuality
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QD
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
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DP
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MQRankSum
type: SiteQuality
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BaseQRankSum
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SIO_000300: 3.76e0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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East Asian
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allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

African
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South Asian
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allele frequency: 3.028467595396729e-4
allele num: 16510
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
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European (Non-Finnish)
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allele count: 4
allele frequency: 5.996282304970918e-5
allele num: 66708
num of homozygotes: 0

Other
type: Population
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Latino
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allele frequency: 4.320027648176948e-4
allele num: 11574
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VQSLOD
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DP
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ReadPosRankSum
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QD
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MQ
type: SiteQuality
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BaseQRankSum
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MQRankSum
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FS
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ClippingRankSum
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InbreedingCoeff
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

Latino
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allele frequency: 0.0e0
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East Asian
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African
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South Asian
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European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66686
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Other
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DP
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QD
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
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VQSLOD
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MQ
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BaseQRankSum
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MQRankSum
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InbreedingCoeff
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FS
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66676
num of homozygotes: 0

East Asian
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allele frequency: 1.155535012710885e-4
allele num: 8654
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

Latino
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South Asian
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Other
type: Population
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African
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DP
type: SiteQuality
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MQRankSum
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MQ
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ReadPosRankSum
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VQSLOD
type: SiteQuality
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InbreedingCoeff
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BaseQRankSum
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FS
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QD
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 1

South Asian
type: Population
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allele frequency: 6.081245439065921e-5
allele num: 16444
num of homozygotes: 0

European (Finnish)
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allele frequency: 0.0e0
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East Asian
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allele frequency: 0.0e0
allele num: 8654
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Latino
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Other
type: Population
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African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10394
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European (Non-Finnish)
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allele count: 0
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allele num: 66660
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ReadPosRankSum
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BaseQRankSum
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QD
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DP
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ClippingRankSum
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VQSLOD
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MQRankSum
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FS
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InbreedingCoeff
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MQ
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 3.25e1
variant carriers: 0

GenotypeQuality
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bin: 7.75e1
variant carriers: 0

GenotypeQuality
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bin: 8.75e1
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GenotypeQuality
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bin: 5.25e1
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GenotypeQuality
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bin: 2.25e1
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GenotypeQuality
all individuals: 33301
bin: 9.75e1
variant carriers: 4

GenotypeQuality
all individuals: 218
bin: 4.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 1
allele frequency: 1.51285930408472e-4
allele num: 6610
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66656
num of homozygotes: 0

Latino
type: Population
allele count: 3
allele frequency: 2.592912705272256e-4
allele num: 11570
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10394
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16440
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: -4.457e0

MQ
type: SiteQuality
SIO_000300: 5.933e1

ClippingRankSum
type: SiteQuality
SIO_000300: 1.86e-1

VQSLOD
type: SiteQuality
SIO_000300: -7.238e-1

DP
type: SiteQuality
SIO_000300: 2.885718e6

MQRankSum
type: SiteQuality
SIO_000300: 1.14e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 9.7e-3

FS
type: SiteQuality
SIO_000300: 9.052e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 3.15e-1

QD
type: SiteQuality
SIO_000300: 1.483e1

GenotypeQuality
all individuals: 3569
bin: 6.75e1
variant carriers: 0

GenotypeQuality
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bin: 6.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 2.5e0
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 8.75e1
variant carriers: 0

GenotypeQuality
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bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 33294
bin: 9.75e1
variant carriers: 1

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6606
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11562
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16420
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.500420117632937e-5
allele num: 66648
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10392
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: -3.51e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.81e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 3.5e-3

DP
type: SiteQuality
SIO_000300: 2.878945e6

MQRankSum
type: SiteQuality
SIO_000300: -1.007e0

ClippingRankSum
type: SiteQuality
SIO_000300: -2.19e0

FS
type: SiteQuality
SIO_000300: 0.0e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

VQSLOD
type: SiteQuality
SIO_000300: 9.15e-1

QD
type: SiteQuality
SIO_000300: 1.356e1

GenotypeQuality
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bin: 8.75e1
variant carriers: 0

GenotypeQuality
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bin: 3.25e1
variant carriers: 0

GenotypeQuality
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bin: 2.5e0
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 8.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10388
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6606
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.501185936890143e-5
allele num: 66614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16358
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11558
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: 2.47e-1

QD
type: SiteQuality
SIO_000300: 1.567e1

FS
type: SiteQuality
SIO_000300: 3.424e0

ClippingRankSum
type: SiteQuality
SIO_000300: 3.65e-1

VQSLOD
type: SiteQuality
SIO_000300: 2.33e-1

DP
type: SiteQuality
SIO_000300: 2.870485e6

MQ
type: SiteQuality
SIO_000300: 5.948e1

MQRankSum
type: SiteQuality
SIO_000300: 2.0e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.7e-3

ReadPosRankSum
type: SiteQuality
SIO_000300: -8.6e-1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
all individuals: 47257
bin: 9.75e1
variant carriers: 5

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11488
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 1
allele frequency: 1.511944360447536e-4
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9136
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 792
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8536
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10214
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 4
allele frequency: 6.244146113019045e-5
allele num: 64060
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.981e1

MQRankSum
type: SiteQuality
SIO_000300: -1.83e-1

DP
type: SiteQuality
SIO_000300: 4.445077e6

BaseQRankSum
type: SiteQuality
SIO_000300: 3.03e0

FS
type: SiteQuality
SIO_000300: 0.0e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.05e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -1.3e-3

VQSLOD
type: SiteQuality
SIO_000300: 1.11e0

QD
type: SiteQuality
SIO_000300: 1.352e1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.56e-1

GenotypeQuality
all individuals: 476
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 267
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1889
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 2500
bin: 2.25e1
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GenotypeQuality
all individuals: 436
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variant carriers: 0

GenotypeQuality
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bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 246
bin: 1.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 10
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GenotypeQuality
all individuals: 1114
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4027
bin: 6.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10216
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8546
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 64150
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11490
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 794
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9424
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: 1.5e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.0e-3

DP
type: SiteQuality
SIO_000300: 4.452495e6

ReadPosRankSum
type: SiteQuality
SIO_000300: 9.22e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

QD
type: SiteQuality
SIO_000300: 1.191e1

FS
type: SiteQuality
SIO_000300: 7.59e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 3.5e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -1.444e0

VQSLOD
type: SiteQuality
SIO_000300: 2.65e-1

GenotypeQuality
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bin: 6.75e1
variant carriers: 0

GenotypeQuality
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bin: 1.25e1
variant carriers: 0

GenotypeQuality
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bin: 6.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 1.75e1
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GenotypeQuality
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bin: 9.75e1
variant carriers: 40

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 9
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GenotypeQuality
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bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 610
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2555
bin: 2.25e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 1
allele frequency: 1.511944360447536e-4
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9434
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11490
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8550
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10216
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 792
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 39
allele frequency: 6.078743102964556e-4
allele num: 64158
num of homozygotes: 0

VQSLOD
type: SiteQuality
SIO_000300: 4.76e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 3.83e-1

MQ
type: SiteQuality
SIO_000300: 5.968e1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.52e0

FS
type: SiteQuality
SIO_000300: 1.226e0

ClippingRankSum
type: SiteQuality
SIO_000300: -4.4e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 7.8e-3

MQRankSum
type: SiteQuality
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DP
type: SiteQuality
SIO_000300: 4.455193e6

QD
type: SiteQuality
SIO_000300: 1.33e1

GenotypeQuality
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bin: 1.25e1
variant carriers: 0

GenotypeQuality
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bin: 6.25e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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bin: 7.25e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11490
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10216
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 792
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8550
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.55865207768322e-5
allele num: 64158
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9434
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: 1.52e0

MQ
type: SiteQuality
SIO_000300: 5.968e1

MQRankSum
type: SiteQuality
SIO_000300: 2.75e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 7.8e-3

FS
type: SiteQuality
SIO_000300: 1.226e0

VQSLOD
type: SiteQuality
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ReadPosRankSum
type: SiteQuality
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QD
type: SiteQuality
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DP
type: SiteQuality
SIO_000300: 4.455193e6

ClippingRankSum
type: SiteQuality
SIO_000300: -4.4e-1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 9.75e1
variant carriers: 2

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10226
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 792
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9648
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11490
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8562
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European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.113712791132146e-5
allele num: 64232
num of homozygotes: 0

VQSLOD
type: SiteQuality
SIO_000300: 1.3e0

FS
type: SiteQuality
SIO_000300: 2.756e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.819e0

MQ
type: SiteQuality
SIO_000300: 5.973e1

ClippingRankSum
type: SiteQuality
SIO_000300: 1.15e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.6e-3

DP
type: SiteQuality
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MQRankSum
type: SiteQuality
SIO_000300: 2.58e-1

QD
type: SiteQuality
SIO_000300: 1.1e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.61e-1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 4.25e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11496
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.553808384350042e-5
allele num: 64358
num of homozygotes: 0

Other
type: Population
allele count: 0
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East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8574
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South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10044
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African
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: 1.42e-1

FS
type: SiteQuality
SIO_000300: 1.808e0

VQSLOD
type: SiteQuality
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MQRankSum
type: SiteQuality
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MQ
type: SiteQuality
SIO_000300: 5.959e1

ReadPosRankSum
type: SiteQuality
SIO_000300: -2.41e-1

DP
type: SiteQuality
SIO_000300: 4.465189e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 4.3e-3

QD
type: SiteQuality
SIO_000300: 1.316e1

ClippingRankSum
type: SiteQuality
SIO_000300: 2.3e-2

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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bin: 2.5e0
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GenotypeQuality
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GenotypeQuality
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bin: 8.25e1
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GenotypeQuality
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bin: 1.75e1
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GenotypeQuality
all individuals: 47260
bin: 9.75e1
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GenotypeQuality
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GenotypeQuality
all individuals: 86
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variant carriers: 0

GenotypeQuality
all individuals: 232
bin: 2.75e1
variant carriers: 0

GenotypeQuality
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bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1135
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 46
bin: 4.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.55077228459773e-5
allele num: 64484
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8582
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11506
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10326
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 800
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10244
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.9e-3

ClippingRankSum
type: SiteQuality
SIO_000300: -2.547e0

VQSLOD
type: SiteQuality
SIO_000300: 1.17e0

FS
type: SiteQuality
SIO_000300: 4.811e0

MQRankSum
type: SiteQuality
SIO_000300: 1.9e-1

DP
type: SiteQuality
SIO_000300: 4.46915e6

MQ
type: SiteQuality
SIO_000300: 5.968e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 7.53e-1

QD
type: SiteQuality
SIO_000300: 1.261e1

BaseQRankSum
type: SiteQuality
SIO_000300: -1.593e0

GenotypeQuality
all individuals: 3414
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 92
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 552
bin: 7.5e0
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GenotypeQuality
all individuals: 1138
bin: 6.75e1
variant carriers: 0

GenotypeQuality
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bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 145
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 42
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 280
bin: 3.25e1
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GenotypeQuality
all individuals: 663
bin: 8.25e1
variant carriers: 0

GenotypeQuality
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bin: 8.75e1
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GenotypeQuality
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bin: 9.25e1
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GenotypeQuality
all individuals: 31
bin: 5.75e1
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GenotypeQuality
all individuals: 647
bin: 7.75e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10244
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10618
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 798
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8590
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 64586
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.691117677733357e-5
allele num: 11506
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 4.472617e6

BaseQRankSum
type: SiteQuality
SIO_000300: -3.916e0

MQRankSum
type: SiteQuality
SIO_000300: 7.19e-1

VQSLOD
type: SiteQuality
SIO_000300: 6.64e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 4.2e-3

FS
type: SiteQuality
SIO_000300: 1.176e0

MQ
type: SiteQuality
SIO_000300: 5.974e1

ReadPosRankSum
type: SiteQuality
SIO_000300: -4.08e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -2.875e0

QD
type: SiteQuality
SIO_000300: 1.057e1

GenotypeQuality
all individuals: 115
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 94
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4544
bin: 6.25e1
variant carriers: 0

GenotypeQuality
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bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 437
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variant carriers: 0

GenotypeQuality
all individuals: 3305
bin: 2.25e1
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GenotypeQuality
all individuals: 62
bin: 1.25e1
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 69
bin: 4.75e1
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GenotypeQuality
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bin: 9.25e1
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GenotypeQuality
all individuals: 286
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 648
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 256
bin: 2.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8600
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 800
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11004
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.544544668231805e-5
allele num: 64744
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11512
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10262
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 4.7e-3

QD
type: SiteQuality
SIO_000300: 1.543e1

ClippingRankSum
type: SiteQuality
SIO_000300: -6.32e-1

MQ
type: SiteQuality
SIO_000300: 5.938e1

ReadPosRankSum
type: SiteQuality
SIO_000300: -3.85e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -1.307e0

FS
type: SiteQuality
SIO_000300: 3.442e0

MQRankSum
type: SiteQuality
SIO_000300: -2.74e-1

DP
type: SiteQuality
SIO_000300: 4.478188e6

VQSLOD
type: SiteQuality
SIO_000300: 2.14e0

GenotypeQuality
all individuals: 44
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 4767
bin: 6.25e1
variant carriers: 0

GenotypeQuality
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bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 175
bin: 3.75e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
all individuals: 331
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variant carriers: 0

GenotypeQuality
all individuals: 50
bin: 2.5e0
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 76
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variant carriers: 0

GenotypeQuality
all individuals: 18
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variant carriers: 0

GenotypeQuality
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variant carriers: 1

GenotypeQuality
all individuals: 657
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 438
bin: 8.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8608
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10278
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.540689612670631e-5
allele num: 64906
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 808
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11408
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11514
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: 4.03e-1

FS
type: SiteQuality
SIO_000300: 4.94e-1

VQSLOD
type: SiteQuality
SIO_000300: -7.18e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.8e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 5.1e-3

ClippingRankSum
type: SiteQuality
SIO_000300: 7.94e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -5.3e-2

MQ
type: SiteQuality
SIO_000300: 5.898e1

QD
type: SiteQuality
SIO_000300: 1.213e1

DP
type: SiteQuality
SIO_000300: 4.482018e6

GenotypeQuality
all individuals: 6275
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1732
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 24
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 191
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variant carriers: 0

GenotypeQuality
all individuals: 12
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variant carriers: 0

GenotypeQuality
all individuals: 99
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variant carriers: 0

GenotypeQuality
all individuals: 181
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GenotypeQuality
all individuals: 11
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GenotypeQuality
all individuals: 90
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GenotypeQuality
all individuals: 628
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variant carriers: 0

GenotypeQuality
all individuals: 47265
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 457
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 71
bin: 4.25e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11556
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 13876
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 866
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.51828009231143e-5
allele num: 65864
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8640
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10332
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: 6.7e-3

MQRankSum
type: SiteQuality
SIO_000300: -5.46e-1

QD
type: SiteQuality
SIO_000300: 1.31e1

ClippingRankSum
type: SiteQuality
SIO_000300: 2.46e0

DP
type: SiteQuality
SIO_000300: 4.512711e6

VQSLOD
type: SiteQuality
SIO_000300: -1.957e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -2.071e0

MQ
type: SiteQuality
SIO_000300: 5.895e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.71e-1

FS
type: SiteQuality
SIO_000300: 3.784e0

GenotypeQuality
all individuals: 82
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 89
bin: 7.5e0
variant carriers: 0

GenotypeQuality
all individuals: 175
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 69
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variant carriers: 0

GenotypeQuality
all individuals: 457
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variant carriers: 0

GenotypeQuality
all individuals: 180
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 712
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 12
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 181
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 551
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variant carriers: 0

GenotypeQuality
all individuals: 77
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variant carriers: 0

GenotypeQuality
all individuals: 1382
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 627
bin: 9.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10336
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.517450682852807e-5
allele num: 65900
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 866
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 13972
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11556
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8642
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: -1.115e0

MQRankSum
type: SiteQuality
SIO_000300: 1.56e0

MQ
type: SiteQuality
SIO_000300: 5.886e1

BaseQRankSum
type: SiteQuality
SIO_000300: -4.475e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 6.2e-3

VQSLOD
type: SiteQuality
SIO_000300: -1.444e0

DP
type: SiteQuality
SIO_000300: 4.514527e6

FS
type: SiteQuality
SIO_000300: 0.0e0

ClippingRankSum
type: SiteQuality
SIO_000300: -5.1e-2

QD
type: SiteQuality
SIO_000300: 1.19e1

GenotypeQuality
all individuals: 91
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 628
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 14
bin: 1.75e1
variant carriers: 0

GenotypeQuality
all individuals: 50
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GenotypeQuality
all individuals: 176
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 78
bin: 7.5e0
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GenotypeQuality
all individuals: 1585
bin: 2.25e1
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GenotypeQuality
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GenotypeQuality
all individuals: 458
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 751
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 73
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 59
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 720
bin: 8.25e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8642
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 65942
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 872
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10340
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 14116
num of homozygotes: 0

Latino
type: Population
allele count: 2
allele frequency: 1.730702665282105e-4
allele num: 11556
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 1.881e0

MQRankSum
type: SiteQuality
SIO_000300: 6.830000000000001e-1

QD
type: SiteQuality
SIO_000300: 1.163e1

VQSLOD
type: SiteQuality
SIO_000300: 1.07e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.67e0

ClippingRankSum
type: SiteQuality
SIO_000300: -3.34e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 8.44e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 7.0e-3

MQ
type: SiteQuality
SIO_000300: 5.968e1

DP
type: SiteQuality
SIO_000300: 4.516311e6

GenotypeQuality
all individuals: 778
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 576
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 467
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 9
bin: 2.5e0
variant carriers: 0

GenotypeQuality
all individuals: 85
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variant carriers: 0

GenotypeQuality
all individuals: 65
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 9
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 119
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 84
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 79
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1493
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 742
bin: 8.25e1
variant carriers: 0

GenotypeQuality
all individuals: 108
bin: 2.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11564
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.509661835748792e-5
allele num: 66240
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10358
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 14752
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 878
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8650
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: 3.99e0

MQ
type: SiteQuality
SIO_000300: 5.983e1

DP
type: SiteQuality
SIO_000300: 4.525983e6

VQSLOD
type: SiteQuality
SIO_000300: 1.13e0

FS
type: SiteQuality
SIO_000300: 6.47e-1

QD
type: SiteQuality
SIO_000300: 1.837e1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.1e-2

ClippingRankSum
type: SiteQuality
SIO_000300: -4.2e-1

MQRankSum
type: SiteQuality
SIO_000300: 7.4e-2

ReadPosRankSum
type: SiteQuality
SIO_000300: -3.8e-2

GenotypeQuality
all individuals: 155
bin: 5.25e1
variant carriers: 152

GenotypeQuality
all individuals: 16
bin: 1.75e1
variant carriers: 14

GenotypeQuality
all individuals: 8
bin: 1.25e1
variant carriers: 4

GenotypeQuality
all individuals: 79
bin: 3.75e1
variant carriers: 70

GenotypeQuality
all individuals: 4220
bin: 6.25e1
variant carriers: 201

GenotypeQuality
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bin: 3.25e1
variant carriers: 58

GenotypeQuality
all individuals: 11
bin: 7.5e0
variant carriers: 5

GenotypeQuality
all individuals: 36
bin: 2.5e0
variant carriers: 3

GenotypeQuality
all individuals: 296
bin: 9.25e1
variant carriers: 232

GenotypeQuality
all individuals: 116
bin: 4.75e1
variant carriers: 110

GenotypeQuality
all individuals: 113
bin: 5.75e1
variant carriers: 105

GenotypeQuality
all individuals: 32
bin: 2.75e1
variant carriers: 27

GenotypeQuality
all individuals: 482
bin: 7.75e1
variant carriers: 230

Other
type: Population
allele count: 632
allele frequency: 6.975717439293598e-1
allele num: 906
num of homozygotes: 224

East Asian
type: Population
allele count: 5814
allele frequency: 6.729166666666667e-1
allele num: 8640
num of homozygotes: 1966

European (Non-Finnish)
type: Population
allele count: 47262
allele frequency: 7.091924011884397e-1
allele num: 66642
num of homozygotes: 16753

European (Finnish)
type: Population
allele count: 4928
allele frequency: 7.4553706505295e-1
allele num: 6610
num of homozygotes: 1849

African
type: Population
allele count: 6258
allele frequency: 6.027740319784242e-1
allele num: 10382
num of homozygotes: 1888

South Asian
type: Population
allele count: 10021
allele frequency: 6.156161690625384e-1
allele num: 16278
num of homozygotes: 3120

Latino
type: Population
allele count: 7510
allele frequency: 6.490924805531547e-1
allele num: 11570
num of homozygotes: 2444

VQSLOD
type: SiteQuality
SIO_000300: 4.25e0

DP
type: SiteQuality
SIO_000300: 7.820969e6

ReadPosRankSum
type: SiteQuality
SIO_000300: 3.62e-1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.643e0

FS
type: SiteQuality
SIO_000300: 5.36e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.61e-2

MQ
type: SiteQuality
SIO_000300: 5.955e1

QD
type: SiteQuality
SIO_000300: 2.219e1

MQRankSum
type: SiteQuality
SIO_000300: 1.42e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 3.2e-2

GenotypeQuality
all individuals: 10
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 46
bin: 2.75e1
variant carriers: 0

GenotypeQuality
all individuals: 1013
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 156
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 120
bin: 3.25e1
variant carriers: 0

GenotypeQuality
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bin: 1.75e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 7.25e1
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GenotypeQuality
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bin: 4.25e1
variant carriers: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66662
num of homozygotes: 0

Latino
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allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

Other
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allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

South Asian
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allele count: 1
allele frequency: 6.119951040391677e-5
allele num: 16340
num of homozygotes: 0

African
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allele frequency: 0.0e0
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MQ
type: SiteQuality
SIO_000300: 5.896e1

MQRankSum
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BaseQRankSum
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SIO_000300: -2.259e0

FS
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SIO_000300: 3.332e0

InbreedingCoeff
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SIO_000300: 1.0e-4

ReadPosRankSum
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DP
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SIO_000300: 5.340297e6

QD
type: SiteQuality
SIO_000300: 1.217e1

VQSLOD
type: SiteQuality
SIO_000300: 2.58e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 2.23e-1

GenotypeQuality
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bin: 5.75e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 6.75e1
variant carriers: 0

African
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allele count: 0
allele frequency: 0.0e0
allele num: 10374
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66662
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

Other
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allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
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allele count: 1
allele frequency: 6.119951040391677e-5
allele num: 16340
num of homozygotes: 0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.259e0

ClippingRankSum
type: SiteQuality
SIO_000300: 2.23e-1

InbreedingCoeff
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DP
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QD
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VQSLOD
type: SiteQuality
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MQ
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FS
type: SiteQuality
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ReadPosRankSum
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SIO_000300: 4.62e-1

MQRankSum
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SIO_000300: 4.14e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 9.25e1
variant carriers: 0

European (Non-Finnish)
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allele count: 2
allele frequency: 3.000210014701029e-5
allele num: 66662
num of homozygotes: 0

Other
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allele num: 904
num of homozygotes: 0

East Asian
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allele count: 1
allele frequency: 1.155535012710885e-4
allele num: 8654
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

African
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allele frequency: 0.0e0
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Latino
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South Asian
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allele frequency: 0.0e0
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MQ
type: SiteQuality
SIO_000300: 5.952e1

InbreedingCoeff
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ReadPosRankSum
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FS
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SIO_000300: 0.0e0

MQRankSum
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ClippingRankSum
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DP
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VQSLOD
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QD
type: SiteQuality
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BaseQRankSum
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SIO_000300: -8.100000000000001e-1

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 2

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

East Asian
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allele num: 8654
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South Asian
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allele num: 16338
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European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66662
num of homozygotes: 0

African
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allele count: 0
allele frequency: 0.0e0
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Other
type: Population
allele count: 0
allele frequency: 0.0e0
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Latino
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allele frequency: 0.0e0
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QD
type: SiteQuality
SIO_000300: 1.498e1

FS
type: SiteQuality
SIO_000300: 0.0e0

MQRankSum
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MQ
type: SiteQuality
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VQSLOD
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DP
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SIO_000300: 5.340816e6

InbreedingCoeff
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SIO_000300: 1.0e-4

ClippingRankSum
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SIO_000300: -2.37e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 6.48e-1

BaseQRankSum
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SIO_000300: -8.100000000000001e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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African
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allele count: 0
allele frequency: 0.0e0
allele num: 10376
num of homozygotes: 0

East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
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allele num: 16342
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66652
num of homozygotes: 0

Other
type: Population
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allele frequency: 0.0e0
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DP
type: SiteQuality
SIO_000300: 5.341013e6

InbreedingCoeff
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FS
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ClippingRankSum
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BaseQRankSum
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ReadPosRankSum
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SIO_000300: -2.64e-1

MQRankSum
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VQSLOD
type: SiteQuality
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MQ
type: SiteQuality
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QD
type: SiteQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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East Asian
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allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

South Asian
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allele count: 0
allele frequency: 0.0e0
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African
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.640055296353897e-5
allele num: 11574
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 66668
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
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BaseQRankSum
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DP
type: SiteQuality
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MQ
type: SiteQuality
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FS
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MQRankSum
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QD
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InbreedingCoeff
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ClippingRankSum
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VQSLOD
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ReadPosRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
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allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 110
allele frequency: 1.649967000659987e-3
allele num: 66668
num of homozygotes: 0

African
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allele frequency: 3.855050115651503e-4
allele num: 10376
num of homozygotes: 0

Latino
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allele count: 19
allele frequency: 1.64161050630724e-3
allele num: 11574
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Other
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allele frequency: 0.0e0
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East Asian
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South Asian
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allele frequency: 6.0960741282614e-5
allele num: 16404
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MQRankSum
type: SiteQuality
SIO_000300: 3.19e-1

FS
type: SiteQuality
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MQ
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ClippingRankSum
type: SiteQuality
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InbreedingCoeff
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BaseQRankSum
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VQSLOD
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ReadPosRankSum
type: SiteQuality
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QD
type: SiteQuality
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DP
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
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allele count: 0
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num of homozygotes: 0

European (Non-Finnish)
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allele count: 1
allele frequency: 1.499970000599988e-5
allele num: 66668
num of homozygotes: 0

African
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East Asian
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Latino
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Other
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South Asian
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ReadPosRankSum
type: SiteQuality
SIO_000300: -9.68e-1

VQSLOD
type: SiteQuality
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FS
type: SiteQuality
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BaseQRankSum
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MQ
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InbreedingCoeff
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DP
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QD
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MQRankSum
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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African
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num of homozygotes: 0

East Asian
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allele frequency: 0.0e0
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South Asian
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Other
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Latino
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European (Non-Finnish)
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allele frequency: 2.999940001199976e-5
allele num: 66668
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European (Finnish)
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ReadPosRankSum
type: SiteQuality
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MQRankSum
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InbreedingCoeff
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VQSLOD
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DP
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QD
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MQ
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ClippingRankSum
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FS
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BaseQRankSum
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GenotypeQuality
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GenotypeQuality
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variant carriers: 18

GenotypeQuality
all individuals: 5587
bin: 6.25e1
variant carriers: 0

GenotypeQuality
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bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 3
bin: 7.5e0
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GenotypeQuality
all individuals: 4
bin: 2.5e0
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GenotypeQuality
all individuals: 80
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 40
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1576
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 31
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 874
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 27
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 37
bin: 2.75e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 16
allele frequency: 2.399664047033415e-4
allele num: 66676
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11574
num of homozygotes: 0

East Asian
type: Population
allele count: 1
allele frequency: 1.155535012710885e-4
allele num: 8654
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10374
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 6.087168249330411e-5
allele num: 16428
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 0.0e0

QD
type: SiteQuality
SIO_000300: 1.33e1

DP
type: SiteQuality
SIO_000300: 5.339125e6

MQRankSum
type: SiteQuality
SIO_000300: 2.28e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.88e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -9.2e-2

InbreedingCoeff
type: SiteQuality
SIO_000300: 0.0e0

MQ
type: SiteQuality
SIO_000300: 5.959e1

VQSLOD
type: SiteQuality
SIO_000300: 4.55e0

BaseQRankSum
type: SiteQuality
SIO_000300: -1.102e0

GenotypeQuality
all individuals: 57
bin: 4.75e1
variant carriers: 0

GenotypeQuality
all individuals: 41
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 64
bin: 3.75e1
variant carriers: 0

GenotypeQuality
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bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 4
bin: 7.5e0
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GenotypeQuality
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bin: 7.25e1
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GenotypeQuality
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bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 492
bin: 8.75e1
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GenotypeQuality
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GenotypeQuality
all individuals: 1040
bin: 7.75e1
variant carriers: 0

GenotypeQuality
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bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 36
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1577
bin: 6.75e1
variant carriers: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8654
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 906
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66678
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10376
num of homozygotes: 0

Latino
type: Population
allele count: 1
allele frequency: 8.640055296353897e-5
allele num: 11574
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16446
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: -1.0e-4

FS
type: SiteQuality
SIO_000300: 1.93e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.379e0

ClippingRankSum
type: SiteQuality
SIO_000300: -7.68e-1

MQRankSum
type: SiteQuality
SIO_000300: -3.78e-1

QD
type: SiteQuality
SIO_000300: 1.413e1

ReadPosRankSum
type: SiteQuality
SIO_000300: -9.26e-1

VQSLOD
type: SiteQuality
SIO_000300: 3.99e-1

MQ
type: SiteQuality
SIO_000300: 5.953e1

DP
type: SiteQuality
SIO_000300: 5.339128e6

GenotypeQuality
all individuals: 431
bin: 7.75e1
variant carriers: 185

GenotypeQuality
all individuals: 25
bin: 4.25e1
variant carriers: 20

GenotypeQuality
all individuals: 276
bin: 7.25e1
variant carriers: 79

GenotypeQuality
all individuals: 4
bin: 1.75e1
variant carriers: 4

GenotypeQuality
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bin: 5.25e1
variant carriers: 48

GenotypeQuality
all individuals: 2
bin: 7.5e0
variant carriers: 1

GenotypeQuality
all individuals: 4140
bin: 6.25e1
variant carriers: 72

GenotypeQuality
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bin: 4.75e1
variant carriers: 39

GenotypeQuality
all individuals: 4
bin: 1.25e1
variant carriers: 1

GenotypeQuality
all individuals: 364
bin: 8.25e1
variant carriers: 196

GenotypeQuality
all individuals: 169
bin: 8.75e1
variant carriers: 128

GenotypeQuality
all individuals: 53774
bin: 9.75e1
variant carriers: 53540

GenotypeQuality
all individuals: 932
bin: 6.75e1
variant carriers: 132

Latino
type: Population
allele count: 7589
allele frequency: 6.555805114029025e-1
allele num: 11576
num of homozygotes: 2497

South Asian
type: Population
allele count: 10123
allele frequency: 6.137383290893659e-1
allele num: 16494
num of homozygotes: 3158

Other
type: Population
allele count: 640
allele frequency: 7.048458149779736e-1
allele num: 908
num of homozygotes: 229

African
type: Population
allele count: 7767
allele frequency: 7.478336221837089e-1
allele num: 10386
num of homozygotes: 2896

European (Finnish)
type: Population
allele count: 4928
allele frequency: 7.453115547489413e-1
allele num: 6612
num of homozygotes: 1849

European (Non-Finnish)
type: Population
allele count: 47343
allele frequency: 7.097262615057116e-1
allele num: 66706
num of homozygotes: 16795

East Asian
type: Population
allele count: 5814
allele frequency: 6.722941720629048e-1
allele num: 8648
num of homozygotes: 1966

VQSLOD
type: SiteQuality
SIO_000300: 4.56e0

ClippingRankSum
type: SiteQuality
SIO_000300: 2.5e-2

MQRankSum
type: SiteQuality
SIO_000300: 1.02e-1

QD
type: SiteQuality
SIO_000300: 2.504e1

DP
type: SiteQuality
SIO_000300: 5.389689e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.41e-2

ReadPosRankSum
type: SiteQuality
SIO_000300: 2.69e-1

FS
type: SiteQuality
SIO_000300: 0.0e0

MQ
type: SiteQuality
SIO_000300: 5.96e1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.3e0

GenotypeQuality
all individuals: 30
bin: 5.75e1
variant carriers: 0

GenotypeQuality
all individuals: 649
bin: 9.25e1
variant carriers: 0

GenotypeQuality
all individuals: 275
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 37
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variant carriers: 0

GenotypeQuality
all individuals: 2340
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variant carriers: 0

GenotypeQuality
all individuals: 2
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variant carriers: 0

GenotypeQuality
all individuals: 40732
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
all individuals: 8962
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GenotypeQuality
all individuals: 2900
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GenotypeQuality
all individuals: 1707
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variant carriers: 0

GenotypeQuality
all individuals: 535
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 61
bin: 5.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.50073536032656e-5
allele num: 66634
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10358
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11566
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16370
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 5.973e1

MQRankSum
type: SiteQuality
SIO_000300: -1.29e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 2.59e0

ClippingRankSum
type: SiteQuality
SIO_000300: -3.57e-1

QD
type: SiteQuality
SIO_000300: 1.382e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.55e-1

FS
type: SiteQuality
SIO_000300: 2.201e0

DP
type: SiteQuality
SIO_000300: 1.763322e6

BaseQRankSum
type: SiteQuality
SIO_000300: -2.916e0

GenotypeQuality
all individuals: 535
bin: 8.75e1
variant carriers: 0

GenotypeQuality
all individuals: 2900
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 45
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 1707
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variant carriers: 0

GenotypeQuality
all individuals: 649
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GenotypeQuality
all individuals: 2323
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variant carriers: 13

GenotypeQuality
all individuals: 2
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GenotypeQuality
all individuals: 3
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variant carriers: 0

GenotypeQuality
all individuals: 61
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variant carriers: 0

GenotypeQuality
all individuals: 8962
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variant carriers: 0

GenotypeQuality
all individuals: 37
bin: 3.75e1
variant carriers: 0

GenotypeQuality
all individuals: 275
bin: 2.25e1
variant carriers: 0

GenotypeQuality
all individuals: 30
bin: 5.75e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 6
allele frequency: 9.004412161959359e-5
allele num: 66634
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 908
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16370
num of homozygotes: 0

Latino
type: Population
allele count: 7
allele frequency: 6.052222030088189e-4
allele num: 11566
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10358
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6612
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: -1.29e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -3.57e-1

VQSLOD
type: SiteQuality
SIO_000300: 2.59e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.916e0

QD
type: SiteQuality
SIO_000300: 1.382e1

MQ
type: SiteQuality
SIO_000300: 5.973e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.55e-1

FS
type: SiteQuality
SIO_000300: 2.201e0

DP
type: SiteQuality
SIO_000300: 1.763322e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.0e-4

GenotypeQuality
all individuals: 2
bin: 1.25e1
variant carriers: 0

GenotypeQuality
all individuals: 8917
bin: 6.75e1
variant carriers: 0

GenotypeQuality
all individuals: 49
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variant carriers: 0

GenotypeQuality
all individuals: 1693
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variant carriers: 0

GenotypeQuality
all individuals: 2871
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 4
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variant carriers: 0

GenotypeQuality
all individuals: 22
bin: 4.25e1
variant carriers: 0

GenotypeQuality
all individuals: 67
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variant carriers: 0

GenotypeQuality
all individuals: 40607
bin: 6.25e1
variant carriers: 0

GenotypeQuality
all individuals: 2296
bin: 9.75e1
variant carriers: 2

GenotypeQuality
all individuals: 410
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variant carriers: 0

GenotypeQuality
all individuals: 2327
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 60
bin: 3.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66590
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10344
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16288
num of homozygotes: 0

Latino
type: Population
allele count: 2
allele frequency: 1.731301939058172e-4
allele num: 11552
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: 6.81e-1

MQRankSum
type: SiteQuality
SIO_000300: -4.61e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -4.77e-1

FS
type: SiteQuality
SIO_000300: 1.941e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -5.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 8.05e-1

DP
type: SiteQuality
SIO_000300: 1.759143e6

MQ
type: SiteQuality
SIO_000300: 6.0e1

BaseQRankSum
type: SiteQuality
SIO_000300: -3.629e0

QD
type: SiteQuality
SIO_000300: 1.086e1

GenotypeQuality
all individuals: 1
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variant carriers: 0

GenotypeQuality
all individuals: 59
bin: 3.25e1
variant carriers: 0

GenotypeQuality
all individuals: 426
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variant carriers: 0

GenotypeQuality
all individuals: 81
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GenotypeQuality
all individuals: 4
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GenotypeQuality
all individuals: 8
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GenotypeQuality
all individuals: 4
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GenotypeQuality
all individuals: 23
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GenotypeQuality
all individuals: 40653
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variant carriers: 0

GenotypeQuality
all individuals: 47
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GenotypeQuality
all individuals: 8912
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variant carriers: 0

GenotypeQuality
all individuals: 2323
bin: 7.25e1
variant carriers: 0

GenotypeQuality
all individuals: 527
bin: 8.75e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11548
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 66574
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 9.667440061871617e-5
allele num: 10344
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16280
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.758559e6

ClippingRankSum
type: SiteQuality
SIO_000300: -3.14e-1

MQRankSum
type: SiteQuality
SIO_000300: 1.82e0

FS
type: SiteQuality
SIO_000300: 0.0e0

ReadPosRankSum
type: SiteQuality
SIO_000300: 0.0e0

VQSLOD
type: SiteQuality
SIO_000300: -5.344e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

QD
type: SiteQuality
SIO_000300: 1.069e1

InbreedingCoeff
type: SiteQuality
SIO_000300: -5.0e-4

BaseQRankSum
type: SiteQuality
SIO_000300: 6.55e-1

GenotypeQuality
all individuals: 2840
bin: 7.75e1
variant carriers: 0

GenotypeQuality
all individuals: 642
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GenotypeQuality
all individuals: 76
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GenotypeQuality
all individuals: 2311
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GenotypeQuality
all individuals: 1678
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variant carriers: 0

GenotypeQuality
all individuals: 61
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GenotypeQuality
all individuals: 8889
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variant carriers: 0

GenotypeQuality
all individuals: 12
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variant carriers: 0

GenotypeQuality
all individuals: 8
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GenotypeQuality
all individuals: 48
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GenotypeQuality
all individuals: 2281
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variant carriers: 1

GenotypeQuality
all individuals: 92
bin: 5.25e1
variant carriers: 0

GenotypeQuality
all individuals: 74
bin: 5.75e1
variant carriers: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6608
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8652
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 16250
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10342
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.502268425322237e-5
allele num: 66566
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11548
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 904
num of homozygotes: 0

QD
type: SiteQuality
SIO_000300: 1.108e1

MQRankSum
type: SiteQuality
SIO_000300: 8.599999999999999e-2

ReadPosRankSum
type: SiteQuality
SIO_000300: 4.69e-1

VQSLOD
type: SiteQuality
SIO_000300: 4.33e-1

MQ
type: SiteQuality
SIO_000300: 5.9e1

ClippingRankSum
type: SiteQuality
SIO_000300: -7.5e-2

InbreedingCoeff
type: SiteQuality
SIO_000300: -5.0e-4

BaseQRankSum
type: SiteQuality
SIO_000300: -1.892e0

FS
type: SiteQuality
SIO_000300: 1.163e0

DP
type: SiteQuality
SIO_000300: 1.758026e6

GenotypeQuality
all individuals: 2266
bin: 9.75e1
variant carriers: 1

GenotypeQuality
all individuals: 10
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variant carriers: 0

GenotypeQuality
all individuals: 2783
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GenotypeQuality
all individuals: 8779
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GenotypeQuality
all individuals: 1008
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GenotypeQuality
all individuals: 40305
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GenotypeQuality
all individuals: 52
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GenotypeQuality
all individuals: 53
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GenotypeQuality
all individuals: 28
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GenotypeQuality
all individuals: 155
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GenotypeQuality
all individuals: 22
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GenotypeQuality
all individuals: 632
bin: 9.25e1
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GenotypeQuality
all individuals: 516
bin: 8.75e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11516
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8650
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 896
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 15938
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10280
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.504800312998465e-5
allele num: 66454
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6610
num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
SIO_000300: 9.68e-1

DP
type: SiteQuality
SIO_000300: 1.745692e6

InbreedingCoeff
type: SiteQuality
SIO_000300: -4.0e-4

VQSLOD
type: SiteQuality
SIO_000300: 1.05e0

ClippingRankSum
type: SiteQuality
SIO_000300: -3.58e-1

MQRankSum
type: SiteQuality
SIO_000300: 4.6e-2

BaseQRankSum
type: SiteQuality
SIO_000300: 1.02e0

FS
type: SiteQuality
SIO_000300: 2.286e0

QD
type: SiteQuality
SIO_000300: 1.41e1

MQ
type: SiteQuality
SIO_000300: 5.956e1

GenotypeQuality
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bin: 4.75e1
variant carriers: 0

GenotypeQuality
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bin: 3.25e1
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GenotypeQuality
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bin: 2.25e1
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GenotypeQuality
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bin: 4.25e1
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GenotypeQuality
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GenotypeQuality
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bin: 7.5e0
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GenotypeQuality
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bin: 5.75e1
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GenotypeQuality
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GenotypeQuality
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bin: 9.25e1
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 501
bin: 8.75e1
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GenotypeQuality
all individuals: 2257
bin: 9.75e1
variant carriers: 2

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11386
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 874
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 14532
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.041917624870719e-5
allele num: 65748
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10032
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8618
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6598
num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: 2.82e-1

QD
type: SiteQuality
SIO_000300: 1.584e1

FS
type: SiteQuality
SIO_000300: 3.893e0

MQ
type: SiteQuality
SIO_000300: 5.928e1

VQSLOD
type: SiteQuality
SIO_000300: 3.55e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.82e0

DP
type: SiteQuality
SIO_000300: 1.692765e6

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.8e-3

ClippingRankSum
type: SiteQuality
SIO_000300: -7.13e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: -5.0e-2

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 608
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variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11054
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8436
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9668
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.556226462074761e-5
allele num: 64258
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 826
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6554
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 13034
num of homozygotes: 0

VQSLOD
type: SiteQuality
SIO_000300: -2.231e0

MQ
type: SiteQuality
SIO_000300: 5.925e1

FS
type: SiteQuality
SIO_000300: 1.603e0

ReadPosRankSum
type: SiteQuality
SIO_000300: -1.914e0

DP
type: SiteQuality
SIO_000300: 1.608629e6

BaseQRankSum
type: SiteQuality
SIO_000300: 2.25e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 1.5e-3

ClippingRankSum
type: SiteQuality
SIO_000300: -1.359e0

MQRankSum
type: SiteQuality
SIO_000300: -1.692e0

QD
type: SiteQuality
SIO_000300: 9.66e0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 2573
bin: 5.25e1
variant carriers: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.612903225806452e-5
allele num: 62000
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8152
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10632
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 788
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 11768
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9234
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6484
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 1.378e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.27e0

ClippingRankSum
type: SiteQuality
SIO_000300: 1.26e0

DP
type: SiteQuality
SIO_000300: 1.486841e6

VQSLOD
type: SiteQuality
SIO_000300: 4.19e-1

MQRankSum
type: SiteQuality
SIO_000300: -1.32e-1

InbreedingCoeff
type: SiteQuality
SIO_000300: 0.0e0

BaseQRankSum
type: SiteQuality
SIO_000300: 2.5e0

QD
type: SiteQuality
SIO_000300: 9.25e0

GenotypeQuality
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bin: 2.5e0
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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variant carriers: 0

African
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allele count: 0
allele frequency: 0.0e0
allele num: 9232
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 8.5295121119072e-5
allele num: 11724
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6482
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 788
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8150
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10626
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 61950
num of homozygotes: 0

FS
type: SiteQuality
SIO_000300: 1.612e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.367e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.7e-3

VQSLOD
type: SiteQuality
SIO_000300: -1.299e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

DP
type: SiteQuality
SIO_000300: 1.479767e6

MQRankSum
type: SiteQuality
SIO_000300: -4.3e-2

ReadPosRankSum
type: SiteQuality
SIO_000300: -5.9e-2

QD
type: SiteQuality
SIO_000300: 5.91e0

ClippingRankSum
type: SiteQuality
SIO_000300: -5.3e-1

GenotypeQuality
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bin: 2.5e0
variant carriers: 0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
all individuals: 211
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variant carriers: 0

GenotypeQuality
all individuals: 884
bin: 7.25e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10626
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 61950
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9232
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6482
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 788
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8150
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 8.5295121119072e-5
allele num: 11724
num of homozygotes: 0

MQ
type: SiteQuality
SIO_000300: 6.0e1

MQRankSum
type: SiteQuality
SIO_000300: -4.3e-2

DP
type: SiteQuality
SIO_000300: 1.479767e6

ReadPosRankSum
type: SiteQuality
SIO_000300: -5.9e-2

QD
type: SiteQuality
SIO_000300: 5.91e0

InbreedingCoeff
type: SiteQuality
SIO_000300: 2.7e-3

VQSLOD
type: SiteQuality
SIO_000300: -1.299e0

FS
type: SiteQuality
SIO_000300: 1.612e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.367e0

ClippingRankSum
type: SiteQuality
SIO_000300: -5.3e-1

GenotypeQuality
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bin: 1.75e1
variant carriers: 0

GenotypeQuality
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variant carriers: 2

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
all individuals: 282
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GenotypeQuality
all individuals: 772
bin: 7.25e1
variant carriers: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8868
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6360
num of homozygotes: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10698
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10022
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 764
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 2
allele frequency: 3.370748643273671e-5
allele num: 59334
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 7746
num of homozygotes: 0

ClippingRankSum
type: SiteQuality
SIO_000300: -4.22e-1

DP
type: SiteQuality
SIO_000300: 1.347505e6

ReadPosRankSum
type: SiteQuality
SIO_000300: 1.11e0

MQRankSum
type: SiteQuality
SIO_000300: 3.45e-1

QD
type: SiteQuality
SIO_000300: 1.2e1

VQSLOD
type: SiteQuality
SIO_000300: 1.06e0

BaseQRankSum
type: SiteQuality
SIO_000300: -2.839e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -9.0e-4

FS
type: SiteQuality
SIO_000300: 1.274e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

GenotypeQuality
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bin: 3.75e1
variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 10054
num of homozygotes: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 9504
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8568
num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 7386
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 1
allele frequency: 1.747457449411107e-5
allele num: 57226
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6238
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 742
num of homozygotes: 0

DP
type: SiteQuality
SIO_000300: 1.232407e6

InbreedingCoeff
type: SiteQuality
SIO_000300: -2.3e-3

BaseQRankSum
type: SiteQuality
SIO_000300: 3.68e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

QD
type: SiteQuality
SIO_000300: 9.52e0

FS
type: SiteQuality
SIO_000300: 0.0e0

VQSLOD
type: SiteQuality
SIO_000300: 2.04e-1

MQRankSum
type: SiteQuality
SIO_000300: 6.0e-1

ReadPosRankSum
type: SiteQuality
SIO_000300: -3.77e-1

ClippingRankSum
type: SiteQuality
SIO_000300: 1.13e0

GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 319
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GenotypeQuality
all individuals: 291
bin: 9.25e1
variant carriers: 0

Latino
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 8634
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6024
num of homozygotes: 0

South Asian
type: Population
allele count: 1
allele frequency: 1.197604790419162e-4
allele num: 8350
num of homozygotes: 0

African
type: Population
allele count: 0
allele frequency: 0.0e0
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East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6690
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 53036
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 696
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ReadPosRankSum
type: SiteQuality
SIO_000300: 5.33e-1

ClippingRankSum
type: SiteQuality
SIO_000300: -1.2e0

InbreedingCoeff
type: SiteQuality
SIO_000300: -6.1e-3

QD
type: SiteQuality
SIO_000300: 1.89e1

DP
type: SiteQuality
SIO_000300: 9.71895e5

FS
type: SiteQuality
SIO_000300: 4.472e0

BaseQRankSum
type: SiteQuality
SIO_000300: 2.93e0

MQ
type: SiteQuality
SIO_000300: 6.0e1

MQRankSum
type: SiteQuality
SIO_000300: 1.6e0

VQSLOD
type: SiteQuality
SIO_000300: -1.266e0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
all individuals: 1923
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GenotypeQuality
all individuals: 1123
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variant carriers: 0

Latino
type: Population
allele count: 1
allele frequency: 1.204238921001927e-4
allele num: 8304
num of homozygotes: 0

European (Non-Finnish)
type: Population
allele count: 18
allele frequency: 3.478529741429289e-4
allele num: 51746
num of homozygotes: 0

African
type: Population
allele count: 1
allele frequency: 1.315097317201473e-4
allele num: 7604
num of homozygotes: 0

European (Finnish)
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 5950
num of homozygotes: 0

Other
type: Population
allele count: 0
allele frequency: 0.0e0
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South Asian
type: Population
allele count: 0
allele frequency: 0.0e0
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num of homozygotes: 0

East Asian
type: Population
allele count: 0
allele frequency: 0.0e0
allele num: 6496
num of homozygotes: 0

InbreedingCoeff
type: SiteQuality
SIO_000300: -5.8e-3

BaseQRankSum
type: SiteQuality
SIO_000300: 1.38e0

MQRankSum
type: SiteQuality
SIO_000300: -1.52e-1

MQ
type: SiteQuality
SIO_000300: 6.0e1

ClippingRankSum
type: SiteQuality
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QD
type: SiteQuality
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FS
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VQSLOD
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ReadPosRankSum
type: SiteQuality
SIO_000300: 2.53e-1

DP
type: SiteQuality
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GenotypeQuality
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variant carriers: 0

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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bin: 4.75e1
variant carriers: 0

Other
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allele frequency: 0.0e0
allele num: 634
num of homozygotes: 0

African
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South Asian
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East Asian
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allele frequency: 0.0e0
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European (Non-Finnish)
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allele num: 49832
num of homozygotes: 0

Latino
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allele frequency: 0.0e0
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European (Finnish)
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BaseQRankSum
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ClippingRankSum
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MQ
type: SiteQuality
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DP
type: SiteQuality
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FS
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ReadPosRankSum
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QD
type: SiteQuality
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InbreedingCoeff
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MQRankSum
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VQSLOD
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Finnish)
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allele frequency: 0.0e0
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num of homozygotes: 0

African
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allele frequency: 1.385041551246538e-4
allele num: 7220
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South Asian
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Other
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allele frequency: 0.0e0
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European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
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East Asian
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allele frequency: 0.0e0
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Latino
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allele frequency: 0.0e0
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num of homozygotes: 0

MQRankSum
type: SiteQuality
SIO_000300: -6.33e-1

BaseQRankSum
type: SiteQuality
SIO_000300: 1.13e0

MQ
type: SiteQuality
SIO_000300: 5.414e1

InbreedingCoeff
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SIO_000300: -9.2e-3

ClippingRankSum
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QD
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VQSLOD
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FS
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DP
type: SiteQuality
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ReadPosRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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South Asian
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allele num: 16510
num of homozygotes: 0

Latino
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allele count: 0
allele frequency: 0.0e0
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African
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Other
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East Asian
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allele frequency: 0.0e0
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European (Finnish)
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allele count: 0
allele frequency: 0.0e0
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European (Non-Finnish)
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allele frequency: 0.0e0
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num of homozygotes: 0

ReadPosRankSum
type: SiteQuality
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MQ
type: SiteQuality
SIO_000300: 6.0e1

MQRankSum
type: SiteQuality
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VQSLOD
type: SiteQuality
SIO_000300: 1.38e0

FS
type: SiteQuality
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DP
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InbreedingCoeff
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SIO_000300: -4.0e-4

QD
type: SiteQuality
SIO_000300: 1.154e1

BaseQRankSum
type: SiteQuality
SIO_000300: -5.845e0

ClippingRankSum
type: SiteQuality
SIO_000300: -1.05e-1

GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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South Asian
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Other
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allele frequency: 0.0e0
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European (Non-Finnish)
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allele num: 66740
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European (Finnish)
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allele frequency: 0.0e0
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Latino
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African
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East Asian
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ReadPosRankSum
type: SiteQuality
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DP
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ClippingRankSum
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QD
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BaseQRankSum
type: SiteQuality
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MQ
type: SiteQuality
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FS
type: SiteQuality
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VQSLOD
type: SiteQuality
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InbreedingCoeff
type: SiteQuality
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MQRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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South Asian
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allele num: 16510
num of homozygotes: 0

African
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allele frequency: 0.0e0
allele num: 10406
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European (Finnish)
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allele frequency: 0.0e0
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Latino
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European (Non-Finnish)
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Other
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East Asian
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QD
type: SiteQuality
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VQSLOD
type: SiteQuality
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BaseQRankSum
type: SiteQuality
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MQ
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SIO_000300: 5.915e1

FS
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DP
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InbreedingCoeff
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ReadPosRankSum
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MQRankSum
type: SiteQuality
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ClippingRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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variant carriers: 0

European (Finnish)
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allele frequency: 0.0e0
allele num: 6614
num of homozygotes: 0

European (Non-Finnish)
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allele count: 0
allele frequency: 0.0e0
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South Asian
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Latino
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African
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allele num: 10406
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East Asian
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Other
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VQSLOD
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InbreedingCoeff
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DP
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MQRankSum
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ClippingRankSum
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QD
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BaseQRankSum
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MQ
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FS
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ReadPosRankSum
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Finnish)
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European (Non-Finnish)
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East Asian
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Other
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Latino
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South Asian
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African
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MQ
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FS
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MQRankSum
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BaseQRankSum
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ClippingRankSum
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ReadPosRankSum
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QD
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InbreedingCoeff
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VQSLOD
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DP
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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GenotypeQuality
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European (Non-Finnish)
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European (Finnish)
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African
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South Asian
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Other
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Latino
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East Asian
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ReadPosRankSum
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DP
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QD
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InbreedingCoeff
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BaseQRankSum
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VQSLOD
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MQ
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FS
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ClippingRankSum
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MQRankSum
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