http://purl.uniprot.org/uniprot/A0A0D4E306
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 22
mnemonic: A0A0D4E306_CORHA
citation: SIP45F7528490734893
recommended name: SIP01806B802B154B42
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIPA710FD4E8562164E
annotation: SIP35E10EBC52420075
annotation: SIP76987E8D6C1B7456
annotation: SIP6154A3EBB494C2AC
annotation: SIPFD2FD7A808C37C35
annotation: SIP3A586EABDA5239A3
annotation: SIPBBAF958ED067860D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0045263
classified with: GO_0015078
classified with: GO_0015986
sequence: http://purl.uniprot.org/isoforms/A0A0D4E306-1

SIP45F7528490734893
type: Journal Citation
title: Effects of inbreeding and parental incubation on captive breeding success in Hawaiian crows.
author: Hoeck P.E.
author: Wolak M.E.
author: Switzer R.A.
author: Kuehler C.M.
author: Lieberman A.A.
date: 2015
name: Biol. Conserv.
volume: 184
pages: 357-364

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR000568
type: Resource
database: InterPro
comment: ATP_synth_F0_asu

IPR023011
type: Resource
database: InterPro
comment: ATP_synth_F0_asu_AS

IPR045083
type: Resource
database: InterPro
comment: ATP_synth_F0_asu_bact/mt

IPR035908
type: Resource
database: InterPro
comment: F0_ATP_A_sf

PTHR11410
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT A
signature sequence match: PANTHER PTHR11410 match 1

PF00119
type: Resource
database: Pfam
comment: ATP-synt_A
signature sequence match: Pfam PF00119 match 1

PR00123
type: Resource
database: PRINTS
comment: ATPASEA

SSF81336
type: Resource
database: SUPFAM
comment: F1F0 ATP synthase subunit A
signature sequence match: SUPFAM SSF81336 match 1

TIGR01131
type: Resource
database: TIGRFAMs
comment: ATP_synt_6_or_A
signature sequence match: TIGRFAMs TIGR01131 match 1

PS00449
type: Resource
database: PROSITE
comment: ATPASE_A
signature sequence match: PROSITE PS00449 match 1

SIP01806B802B154B42
type: Structured Name
full name: ATP synthase subunit a

ATP6
type: Gene

SIPA710FD4E8562164E
type: Function Annotation
comment: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.

SIP76987E8D6C1B7456
type: Similarity Annotation
comment: Belongs to the ATPase A chain family.

SIP6154A3EBB494C2AC
type: Transmembrane Annotation
comment: Helical
range: -9218585569268852690tt12tt31

-9218585569268852690tt12
type: Position
type: ExactPosition
position: 12
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

-9218585569268852690tt31
type: Position
type: ExactPosition
position: 31
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

SIPFD2FD7A808C37C35
type: Transmembrane Annotation
comment: Helical
range: -9218585569268852690tt69tt89

-9218585569268852690tt69
type: Position
type: ExactPosition
position: 69
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

-9218585569268852690tt89
type: Position
type: ExactPosition
position: 89
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

SIP3A586EABDA5239A3
type: Transmembrane Annotation
comment: Helical
range: -9218585569268852690tt101tt118

-9218585569268852690tt101
type: Position
type: ExactPosition
position: 101
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

-9218585569268852690tt118
type: Position
type: ExactPosition
position: 118
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

SIPBBAF958ED067860D
type: Transmembrane Annotation
comment: Helical
range: -9218585569268852690tt195tt223

-9218585569268852690tt195
type: Position
type: ExactPosition
position: 195
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

-9218585569268852690tt223
type: Position
type: ExactPosition
position: 223
reference: http://purl.uniprot.org/isoforms/A0A0D4E306-1

http://purl.uniprot.org/isoforms/A0A0D4E306-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 24886
value: MNLSFFNQFSSPSLLGIPLILIAMTFPALLLPTQGNRWITDRLSTLQTWFINLVTKQLMMPLSNKGHKWALILTSLMMFLLLTNLLGLLPYTFTPTTQLSMNLALAVPLWLATLLVGLRNQPSISLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGHLLIQLISTATVALASTMPTISLLTLLILLLLTILEVAVAMIQAYVFVLLLSLYLQENI

http://purl.uniprot.org/uniprot/A0A0D4E302
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 23
mnemonic: A0A0D4E302_CORHA
citation: SIP45F7528490734893
recommended name: SIPD7C66A1752115876
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP4C698CB487AEB019
annotation: SIP30E7B2F84480ACDC
annotation: SIPDFEE848E1E85B381
annotation: SIP22F2B61E43521B61
annotation: SIPEB48C7D7528ADF72
annotation: SIPAD9D05BE702B6E59
annotation: SIP02C037484A808505
annotation: SIP1721EFB56F1A42B1
annotation: SIP898E3F52D5C9AE36
annotation: SIP82F0985587CDEE96
annotation: SIP35A59BBFDF965F99
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0008137
sequence: http://purl.uniprot.org/isoforms/A0A0D4E302-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

MF_01350
type: Resource
database: HAMAP
comment: NDH1_NuoH
signature sequence match: HAMAP MF 01350 match 1

IPR001694
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_su1/FPO

IPR018086
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_su1_CS

PTHR11432
type: Resource
database: PANTHER
comment: NADH DEHYDROGENASE SUBUNIT 1
signature sequence match: PANTHER PTHR11432 match 1

PF00146
type: Resource
database: Pfam
comment: NADHdh
signature sequence match: Pfam PF00146 match 1

PS00667
type: Resource
database: PROSITE
comment: COMPLEX1_ND1_1
signature sequence match: PROSITE PS00667 match 1

PS00668
type: Resource
database: PROSITE
comment: COMPLEX1_ND1_2
signature sequence match: PROSITE PS00668 match 1

SIPD7C66A1752115876
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 1
ec name: 7.1.1.2

NADH1
type: Gene

SIPDFEE848E1E85B381
type: Similarity Annotation
comment: Belongs to the complex I subunit 1 family.

SIP22F2B61E43521B61
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt6tt30

-9218585569268856786tt6
type: Position
type: ExactPosition
position: 6
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt30
type: Position
type: ExactPosition
position: 30
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIPEB48C7D7528ADF72
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt76tt96

-9218585569268856786tt76
type: Position
type: ExactPosition
position: 76
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt96
type: Position
type: ExactPosition
position: 96
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIPAD9D05BE702B6E59
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt108tt128

-9218585569268856786tt108
type: Position
type: ExactPosition
position: 108
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt128
type: Position
type: ExactPosition
position: 128
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIP02C037484A808505
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt149tt167

-9218585569268856786tt149
type: Position
type: ExactPosition
position: 149
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt167
type: Position
type: ExactPosition
position: 167
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIP1721EFB56F1A42B1
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt179tt198

-9218585569268856786tt179
type: Position
type: ExactPosition
position: 179
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt198
type: Position
type: ExactPosition
position: 198
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIP898E3F52D5C9AE36
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt227tt249

-9218585569268856786tt227
type: Position
type: ExactPosition
position: 227
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt249
type: Position
type: ExactPosition
position: 249
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIP82F0985587CDEE96
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt261tt280

-9218585569268856786tt261
type: Position
type: ExactPosition
position: 261
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt280
type: Position
type: ExactPosition
position: 280
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

SIP35A59BBFDF965F99
type: Transmembrane Annotation
comment: Helical
range: -9218585569268856786tt300tt321

-9218585569268856786tt300
type: Position
type: ExactPosition
position: 300
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

-9218585569268856786tt321
type: Position
type: ExactPosition
position: 321
reference: http://purl.uniprot.org/isoforms/A0A0D4E302-1

http://purl.uniprot.org/isoforms/A0A0D4E302-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 36228
value: MANYPILVNLIMALSYAIPILIAVAFLTLVERKILSYMQGRKGPNVVGPFGLLQPVADGVKLFIKEPIRPSTSSPILFITTPMLALLLAITIWTPLPIPFPLADMNLGLLFMLAMSSLAVYSILWSGWASNSKYALIGSLRAVAQTISYEVTLAIILLSIILLSGNYTLSTLAVVQEPLFLIFSCWPLAMMWYVSTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIMLMNTLTVILFFNPSLYNPPQELFPVILATKVLLLSMGFLWIRASYPRFRYDQLMHLLWKNFLPLALALCLWHISMPISYAGLPPYL

http://purl.uniprot.org/uniprot/A0A0D4E245
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 26
mnemonic: A0A0D4E245_CORHA
citation: SIP45F7528490734893
recommended name: SIP35FCC5F74834FC6E
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP86C2D986F87F80DA
annotation: SIPB8E2A551E5C8FA8E
annotation: SIP3C734D2361E01B36
annotation: SIPB95D1076A42E290E
annotation: SIPCD92C9DCB07AAACD
annotation: SIPEC8DD5D8BDEE03DD
annotation: SIP4DFACA94B1A0CE32
annotation: SIP9B18BE46B1BD4E29
annotation: SIP2A12E3E28EA11245
annotation: SIP4A0DBB0A7A5D6CEB
annotation: SIP38F107D27F1ED843
annotation: SIPE59B2EC7A3173E4B
annotation: SIP3FA3CAEC23A1D2B8
annotation: SIP914038C65558DB36
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0031966
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0042773
sequence: http://purl.uniprot.org/isoforms/A0A0D4E245-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR000260
type: Resource
database: InterPro
comment: NADH4_N

IPR010227
type: Resource
database: InterPro
comment: NADH_Q_OxRdtase_chainM/4

IPR003918
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase

IPR001750
type: Resource
database: InterPro
comment: ND/Mrp_mem

PTHR43507
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4
signature sequence match: PANTHER PTHR43507 match 1

PF01059
type: Resource
database: Pfam
comment: Oxidored_q5_N
signature sequence match: Pfam PF01059 match 1

PF00361
type: Resource
database: Pfam
comment: Proton_antipo_M
signature sequence match: Pfam PF00361 match 1
signature sequence match: Pfam PF00361 match 2

PR01437
type: Resource
database: PRINTS
comment: NUOXDRDTASE4

TIGR01972
type: Resource
database: TIGRFAMs
comment: NDH_I_M
signature sequence match: TIGRFAMs TIGR01972 match 1

SIP35FCC5F74834FC6E
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 4
ec name: 7.1.1.2

NADH4
type: Gene

SIP86C2D986F87F80DA
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIPB95D1076A42E290E
type: Similarity Annotation
comment: Belongs to the complex I subunit 4 family.

SIPCD92C9DCB07AAACD
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt116tt133

-9218585569269836754tt116
type: Position
type: ExactPosition
position: 116
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt133
type: Position
type: ExactPosition
position: 133
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIPEC8DD5D8BDEE03DD
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt145tt168

-9218585569269836754tt145
type: Position
type: ExactPosition
position: 145
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt168
type: Position
type: ExactPosition
position: 168
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP4DFACA94B1A0CE32
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt188tt209

-9218585569269836754tt188
type: Position
type: ExactPosition
position: 188
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt209
type: Position
type: ExactPosition
position: 209
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP9B18BE46B1BD4E29
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt221tt239

-9218585569269836754tt221
type: Position
type: ExactPosition
position: 221
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt239
type: Position
type: ExactPosition
position: 239
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP2A12E3E28EA11245
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt259tt278

-9218585569269836754tt259
type: Position
type: ExactPosition
position: 259
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt278
type: Position
type: ExactPosition
position: 278
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP4A0DBB0A7A5D6CEB
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt285tt303

-9218585569269836754tt285
type: Position
type: ExactPosition
position: 285
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt303
type: Position
type: ExactPosition
position: 303
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP38F107D27F1ED843
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt309tt330

-9218585569269836754tt309
type: Position
type: ExactPosition
position: 309
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt330
type: Position
type: ExactPosition
position: 330
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIPE59B2EC7A3173E4B
type: Transmembrane Annotation
comment: Helical
range: -9218585569269836754tt389tt412

-9218585569269836754tt389
type: Position
type: ExactPosition
position: 389
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt412
type: Position
type: ExactPosition
position: 412
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP3FA3CAEC23A1D2B8
type: Domain Extent Annotation
comment: Oxidored_q5_N
range: -9218585569269836754tt1tt108

-9218585569269836754tt1
type: Position
type: ExactPosition
position: 1
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt108
type: Position
type: ExactPosition
position: 108
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

SIP914038C65558DB36
type: Domain Extent Annotation
comment: Proton_antipo_M
range: -9218585569269836754tt112tt403

-9218585569269836754tt112
type: Position
type: ExactPosition
position: 112
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

-9218585569269836754tt403
type: Position
type: ExactPosition
position: 403
reference: http://purl.uniprot.org/isoforms/A0A0D4E245-1

http://purl.uniprot.org/isoforms/A0A0D4E245-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 51275
value: MLKIIIPTIMLLPLTFLSPCKHLWTNVTTHSLLIATVSLQWLVPTYYPSKGLTHWTSIDQISSPLLVLSCWLLPLMLMASQNHLEQEPIIRKRVFITTVITVQPFILLAFSASELMLFYIAFEATLIPTLVLITRWGNQPERLNAGIYLLFYTLASSLPLLITILHLHNQIGTLYFPMLKLSHPTMNNSWTGLLASLALLLAFMVKAPLYGLHLWLPKAHVEAPIAGSMLLAALLLKLGGYGIMRITILVDPSVNNLHYPFITLALWGAVMTSAICLRQIDLKSLIAYSSVSHMGLVIAATMIQTQWAFSGAMILMISHGLTSSMLFCLANTNYERTHSRILLLTRGLQPLLPLMATWWLLANLTNMALPPTTNLMAELTIVVTLFNWSPLTIILTGTTIVLTASYTLYMLMMTQRGMLPSHITSIQNSSTREHLLMALHMIPMILLIFKPELISGVPM

A0A0D4E1W5
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 35
mnemonic: A0A0D4E1W5_CORHA
citation: SIP45F7528490734893
recommended name: SIP99F797808497C9B3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.9
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP6FFB14E59566F626
annotation: SIP2B876CF00D8A98A0
annotation: SIPA95A53084856FEEB
annotation: SIP9BD03E60AF813071
annotation: SIP6E6F0C5E05790582
annotation: SIP58870B69B7C585A6
annotation: SIPC17682DC87220063
annotation: SIP196A80AC56E2DCE3
annotation: SIP79EAD9C792F96BAB
annotation: SIPE362ACC1FE1F0AD3
annotation: SIPCDB90CCB19E7E439
annotation: SIPB1A30DFCE21D6B80
annotation: SIP3AF9CC49AE17EE5B
annotation: SIPFED63A3551A838FA
annotation: SIP53EF17544529A3E7
annotation: SIPF21F3007F64A6859
annotation: SIP2FAB5EE21CF64E74
annotation: SIP1E9ECAC9ED8346CE
annotation: SIPE91482F3E0A632BD
annotation: SIPEB9A3B44EDB90796
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/106
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/915
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0045277
classified with: GO_0004129
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0006119
sequence: A0A0D4E1W5-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

cd01663
type: Resource
database: CDD
comment: Cyt_c_Oxidase_I
signature sequence match: CDD cd01663 match 1

IPR023616
type: Resource
database: InterPro
comment: Cyt_c_oxase-like_su1_dom

IPR036927
type: Resource
database: InterPro
comment: Cyt_c_oxase-like_su1_sf

IPR000883
type: Resource
database: InterPro
comment: Cyt_C_Oxase_1

IPR023615
type: Resource
database: InterPro
comment: Cyt_c_Oxase_su1_BS

IPR033944
type: Resource
database: InterPro
comment: Cyt_c_oxase_su1_dom

PTHR10422
type: Resource
database: PANTHER
comment: CYTOCHROME C OXIDASE SUBUNIT 1
signature sequence match: PANTHER PTHR10422 match 1

PF00115
type: Resource
database: Pfam
comment: COX1
signature sequence match: Pfam PF00115 match 1

PR01165
type: Resource
database: PRINTS
comment: CYCOXIDASEI

SSF81442
type: Resource
database: SUPFAM
comment: Cytochrome c oxidase subunit I-like
signature sequence match: SUPFAM SSF81442 match 1

PS50855
type: Resource
database: PROSITE
comment: COX1
signature sequence match: PROSITE PS50855 match 1

PS00077
type: Resource
database: PROSITE
comment: COX1_CUB
signature sequence match: PROSITE PS00077 match 1

SIP99F797808497C9B3
type: Structured Name
full name: Cytochrome c oxidase subunit 1
ec name: 7.1.1.9

COI
type: Gene

SIP6FFB14E59566F626
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPC17682DC87220063
type: Similarity Annotation
comment: Belongs to the heme-copper respiratory oxidase family.

SIP196A80AC56E2DCE3
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt20tt38

-9218585569270311890tt20
type: Position
type: ExactPosition
position: 20
reference: A0A0D4E1W5-1

-9218585569270311890tt38
type: Position
type: ExactPosition
position: 38
reference: A0A0D4E1W5-1

SIP79EAD9C792F96BAB
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt58tt84

-9218585569270311890tt58
type: Position
type: ExactPosition
position: 58
reference: A0A0D4E1W5-1

-9218585569270311890tt84
type: Position
type: ExactPosition
position: 84
reference: A0A0D4E1W5-1

SIPE362ACC1FE1F0AD3
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt105tt127

-9218585569270311890tt105
type: Position
type: ExactPosition
position: 105
reference: A0A0D4E1W5-1

-9218585569270311890tt127
type: Position
type: ExactPosition
position: 127
reference: A0A0D4E1W5-1

SIPCDB90CCB19E7E439
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt147tt172

-9218585569270311890tt147
type: Position
type: ExactPosition
position: 147
reference: A0A0D4E1W5-1

-9218585569270311890tt172
type: Position
type: ExactPosition
position: 172
reference: A0A0D4E1W5-1

SIPB1A30DFCE21D6B80
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt184tt211

-9218585569270311890tt184
type: Position
type: ExactPosition
position: 184
reference: A0A0D4E1W5-1

-9218585569270311890tt211
type: Position
type: ExactPosition
position: 211
reference: A0A0D4E1W5-1

SIP3AF9CC49AE17EE5B
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt244tt264

-9218585569270311890tt244
type: Position
type: ExactPosition
position: 244
reference: A0A0D4E1W5-1

-9218585569270311890tt264
type: Position
type: ExactPosition
position: 264
reference: A0A0D4E1W5-1

SIPFED63A3551A838FA
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt271tt292

-9218585569270311890tt271
type: Position
type: ExactPosition
position: 271
reference: A0A0D4E1W5-1

-9218585569270311890tt292
type: Position
type: ExactPosition
position: 292
reference: A0A0D4E1W5-1

SIP53EF17544529A3E7
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt304tt328

-9218585569270311890tt304
type: Position
type: ExactPosition
position: 304
reference: A0A0D4E1W5-1

-9218585569270311890tt328
type: Position
type: ExactPosition
position: 328
reference: A0A0D4E1W5-1

SIPF21F3007F64A6859
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt340tt360

-9218585569270311890tt340
type: Position
type: ExactPosition
position: 340
reference: A0A0D4E1W5-1

-9218585569270311890tt360
type: Position
type: ExactPosition
position: 360
reference: A0A0D4E1W5-1

SIP2FAB5EE21CF64E74
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt380tt401

-9218585569270311890tt380
type: Position
type: ExactPosition
position: 380
reference: A0A0D4E1W5-1

-9218585569270311890tt401
type: Position
type: ExactPosition
position: 401
reference: A0A0D4E1W5-1

SIP1E9ECAC9ED8346CE
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt413tt431

-9218585569270311890tt413
type: Position
type: ExactPosition
position: 413
reference: A0A0D4E1W5-1

-9218585569270311890tt431
type: Position
type: ExactPosition
position: 431
reference: A0A0D4E1W5-1

SIPE91482F3E0A632BD
type: Transmembrane Annotation
comment: Helical
range: -9218585569270311890tt451tt474

-9218585569270311890tt451
type: Position
type: ExactPosition
position: 451
reference: A0A0D4E1W5-1

-9218585569270311890tt474
type: Position
type: ExactPosition
position: 474
reference: A0A0D4E1W5-1

SIPEB9A3B44EDB90796
type: Domain Extent Annotation
comment: COX1
range: -9218585569270311890tt1tt512

-9218585569270311890tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0D4E1W5-1

-9218585569270311890tt512
type: Position
type: ExactPosition
position: 512
reference: A0A0D4E1W5-1

A0A0D4E1W5-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 56960
value: MTFTNRWLFSTNHKDIGTLYLIFGAWAGMVGTALSLLIRAELGQPGALLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVESGVGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGISSILGAINFITTAINMKPPALSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNFNTTFFDPAGGGDPVLYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMGMVWAMLSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGIKVFSWLATLHGGTIKWDPPMLWALGFIFLFTIGGLTGIVLANSSLDIALHDTYYVVAHFHYVLSMGAVFAILAGFTHWFPLFTGYTLHSTWAKIHFGVMFVGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNTISSVGSLISLTAVIMLMFIIWEAFASKRKALQPELINTNVEWIHGCPPPFHTFEEPAFVQTQE

http://purl.uniprot.org/uniprot/A0A0D4E308
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 33
mnemonic: A0A0D4E308_CORHA
citation: SIP45F7528490734893
recommended name: SIP9D7E862BB8D3C835
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP358904D27882B744
annotation: SIP8F285FA921C5ECFE
annotation: SIP37CA297784B0D49B
annotation: SIPF248EDEC5E8E7CBE
annotation: SIPDD81200B4A964956
annotation: SIPE51E0F47C191C921
annotation: SIPE90700FCF5419FDA
annotation: SIP1601565E65575963
annotation: SIPE80F92876C9E1369
annotation: SIP4CB26F5832814F16
annotation: SIPE87AD38456DB3183
annotation: SIP021021220127448A
annotation: SIP502441C67A25994F
annotation: SIPECBD2C0C602EBBA0
annotation: SIP3E49D5DAB9832207
annotation: SIP0214637EEC06D9C7
annotation: SIP811D9E21ED293CF9
annotation: SIPB0EA75F26C0D34F0
annotation: SIP6B7E08A765422DE2
annotation: SIP487262FF5EE4782C
annotation: SIPE392338B66B227D0
annotation: SIPE818AFCDF03D98FA
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0008137
classified with: GO_0042773
sequence: http://purl.uniprot.org/isoforms/A0A0D4E308-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR010934
type: Resource
database: InterPro
comment: NADH_DH_su5_C

IPR018393
type: Resource
database: InterPro
comment: NADHpl_OxRdtase_5_subgr

IPR003945
type: Resource
database: InterPro
comment: NU5C-like

IPR001516
type: Resource
database: InterPro
comment: Proton_antipo_N

PTHR42829
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5
signature sequence match: PANTHER PTHR42829 match 1

PF06455
type: Resource
database: Pfam
comment: NADH5_C
signature sequence match: Pfam PF06455 match 1

PF00662
type: Resource
database: Pfam
comment: Proton_antipo_N
signature sequence match: Pfam PF00662 match 1

TIGR01974
type: Resource
database: TIGRFAMs
comment: NDH_I_L
signature sequence match: TIGRFAMs TIGR01974 match 1

SIP9D7E862BB8D3C835
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 5
ec name: 7.1.1.2

NADH5
type: Gene

SIP358904D27882B744
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIPF248EDEC5E8E7CBE
type: Similarity Annotation
comment: Belongs to the complex I subunit 5 family.

SIPDD81200B4A964956
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt6tt25

-9218585569268850642tt6
type: Position
type: ExactPosition
position: 6
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt25
type: Position
type: ExactPosition
position: 25
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPE51E0F47C191C921
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt78tt103

-9218585569268850642tt78
type: Position
type: ExactPosition
position: 78
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt103
type: Position
type: ExactPosition
position: 103
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPE90700FCF5419FDA
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt115tt135

-9218585569268850642tt115
type: Position
type: ExactPosition
position: 115
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt135
type: Position
type: ExactPosition
position: 135
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP1601565E65575963
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt141tt161

-9218585569268850642tt141
type: Position
type: ExactPosition
position: 141
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt161
type: Position
type: ExactPosition
position: 161
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPE80F92876C9E1369
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt173tt192

-9218585569268850642tt173
type: Position
type: ExactPosition
position: 173
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt192
type: Position
type: ExactPosition
position: 192
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP4CB26F5832814F16
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt212tt230

-9218585569268850642tt212
type: Position
type: ExactPosition
position: 212
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt230
type: Position
type: ExactPosition
position: 230
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPE87AD38456DB3183
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt242tt262

-9218585569268850642tt242
type: Position
type: ExactPosition
position: 242
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt262
type: Position
type: ExactPosition
position: 262
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP021021220127448A
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt274tt295

-9218585569268850642tt274
type: Position
type: ExactPosition
position: 274
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt295
type: Position
type: ExactPosition
position: 295
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP502441C67A25994F
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt302tt322

-9218585569268850642tt302
type: Position
type: ExactPosition
position: 302
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt322
type: Position
type: ExactPosition
position: 322
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPECBD2C0C602EBBA0
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt334tt352

-9218585569268850642tt334
type: Position
type: ExactPosition
position: 334
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt352
type: Position
type: ExactPosition
position: 352
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP3E49D5DAB9832207
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt373tt392

-9218585569268850642tt373
type: Position
type: ExactPosition
position: 373
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt392
type: Position
type: ExactPosition
position: 392
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP0214637EEC06D9C7
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt404tt429

-9218585569268850642tt404
type: Position
type: ExactPosition
position: 404
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt429
type: Position
type: ExactPosition
position: 429
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP811D9E21ED293CF9
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt450tt473

-9218585569268850642tt450
type: Position
type: ExactPosition
position: 450
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt473
type: Position
type: ExactPosition
position: 473
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPB0EA75F26C0D34F0
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt485tt503

-9218585569268850642tt485
type: Position
type: ExactPosition
position: 485
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt503
type: Position
type: ExactPosition
position: 503
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP6B7E08A765422DE2
type: Transmembrane Annotation
comment: Helical
range: -9218585569268850642tt581tt602

-9218585569268850642tt581
type: Position
type: ExactPosition
position: 581
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt602
type: Position
type: ExactPosition
position: 602
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIP487262FF5EE4782C
type: Domain Extent Annotation
comment: Proton_antipo_N
range: -9218585569268850642tt73tt120

-9218585569268850642tt73
type: Position
type: ExactPosition
position: 73
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt120
type: Position
type: ExactPosition
position: 120
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPE392338B66B227D0
type: Domain Extent Annotation
comment: Proton_antipo_M
range: -9218585569268850642tt136tt418

-9218585569268850642tt136
type: Position
type: ExactPosition
position: 136
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt418
type: Position
type: ExactPosition
position: 418
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

SIPE818AFCDF03D98FA
type: Domain Extent Annotation
comment: NADH5_C
range: -9218585569268850642tt423tt603

-9218585569268850642tt423
type: Position
type: ExactPosition
position: 423
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

-9218585569268850642tt603
type: Position
type: ExactPosition
position: 603
reference: http://purl.uniprot.org/isoforms/A0A0D4E308-1

http://purl.uniprot.org/isoforms/A0A0D4E308-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 66560
value: MDQMLILNTFMLLTLAVLCTPIIFPMLSDSLKNTPTIITNTVKTSFLISLIPMTMYIHSGMESLTSFWEWKFIMNFKIPISLTMDFYSLTFFPIALFVSWSILQFATWYMASDPHITKFFTFLLLFLIAMLILIISNNLFLLFIGWEGVGIMSFLLISWWHGRAEANTAALQAVLYNRVGDVGLIMCMAWLASTMNTWEIQQISSQDQTPTLPLLGLILAAAGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRTHPLFHNNPTALSLCLCLGALSTLFAATCALTQNDIKKIIAFSTSSQLGLMMVTIGLNLPQLAFLHISTHAFFKAMLFLCSGTIIHSLNGEQDIRKMGGLQKMLPTTTSCMTIGNLALMGTPFLAGFYSKDQIIESLSTSYLNAWALVLTLLATSFTAVYTIRMTLLVQTGYVRIPPLTPMNENNPAVLSSITRLALGSIVAGFLITSYIPPAKTPPMTMPLSIKITALVVTLLGVVLALELSKMTQALILPKQNRFSNFSTTLGYFNPLVHRFISTKLLSGGQNIASHLIDLSWYKLLGPEGLANLQMMASKTATTFHTGLIKAYLGSFALSIFIILLSTY

A0A0D4E2N9
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 25
mnemonic: A0A0D4E2N9_CORHA
citation: SIP45F7528490734893
recommended name: SIP04BB22F94509478D
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP36E30BDA8FD72430
annotation: SIP9DEDBD9EBFDEDEEB
annotation: SIPE9E936A367693D72
annotation: SIP3F7D6AAE85ABE81F
annotation: SIPEC35E8148D4EFDD6
annotation: SIPB4DF1B9C53FAB053
annotation: SIP8611A44EC21EDD44
annotation: SIPB8CDFD20452A45B5
annotation: SIP86249164C211B769
annotation: SIP9ABD6A7A09D0EA83
annotation: SIP2F49D6AC3161159E
annotation: SIP0670C077384E176E
annotation: SIPD2F5415DA3F492C9
annotation: SIP9E7BD379B2070953
annotation: SIP3CDB5E0F5D217105
annotation: SIPF84709301F8938D0
annotation: SIP4B07F1B3FB73E375
annotation: SIP23DA1583935298E3
annotation: SIPEE6A48C31B27A6A3
annotation: SIPF03456BC2424C87B
annotation: SIP1DC4AF55B74761EB
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0045275
classified with: GO_0046872
classified with: GO_0008121
classified with: GO_0022904
sequence: A0A0D4E2N9-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

cd00290
type: Resource
database: CDD
comment: cytochrome_b_C
signature sequence match: CDD cd00290 match 1

cd00284
type: Resource
database: CDD
comment: Cytochrome_b_N
signature sequence match: CDD cd00284 match 1

IPR005798
type: Resource
database: InterPro
comment: Cyt_b/b6_C

IPR036150
type: Resource
database: InterPro
comment: Cyt_b/b6_C_sf

IPR005797
type: Resource
database: InterPro
comment: Cyt_b/b6_N

IPR027387
type: Resource
database: InterPro
comment: Cytb/b6-like_sf

IPR030689
type: Resource
database: InterPro
comment: Cytochrome_b

IPR016174
type: Resource
database: InterPro
comment: Di-haem_cyt_TM

PF00032
type: Resource
database: Pfam
comment: Cytochrom_B_C
signature sequence match: Pfam PF00032 match 1

PF00033
type: Resource
database: Pfam
comment: Cytochrome_B
signature sequence match: Pfam PF00033 match 1

PIRSF038885
type: Resource
database: PIRSF
comment: COB
signature sequence match: PIRSF PIRSF038885 match 1

SSF81648
type: Resource
database: SUPFAM
comment: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
signature sequence match: SUPFAM SSF81648 match 1

SSF81342
type: Resource
database: SUPFAM
comment: Transmembrane di-heme cytochromes
signature sequence match: SUPFAM SSF81342 match 1

PS51003
type: Resource
database: PROSITE
comment: CYTB_CTER
signature sequence match: PROSITE PS51003 match 1

PS51002
type: Resource
database: PROSITE
comment: CYTB_NTER
signature sequence match: PROSITE PS51002 match 1

SIP04BB22F94509478D
type: Structured Name
full name: Cytochrome b

CYTB
type: Gene

SIP36E30BDA8FD72430
type: Function Annotation
comment: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

SIP9DEDBD9EBFDEDEEB
type: Cofactor Annotation
comment: Binds 2 heme groups non-covalently.
cofactor: CHEBI_60344

SIPE9E936A367693D72
type: Cofactor Annotation
comment: Binds 2 heme groups non-covalently.
cofactor: CHEBI_30413

SIPEC35E8148D4EFDD6
type: Similarity Annotation
comment: Belongs to the cytochrome b family.

SIPB4DF1B9C53FAB053
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt31tt53

-9218585569269406674tt31
type: Position
type: ExactPosition
position: 31
reference: A0A0D4E2N9-1

-9218585569269406674tt53
type: Position
type: ExactPosition
position: 53
reference: A0A0D4E2N9-1

SIP8611A44EC21EDD44
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt88tt108

-9218585569269406674tt88
type: Position
type: ExactPosition
position: 88
reference: A0A0D4E2N9-1

-9218585569269406674tt108
type: Position
type: ExactPosition
position: 108
reference: A0A0D4E2N9-1

SIPB8CDFD20452A45B5
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt114tt134

-9218585569269406674tt114
type: Position
type: ExactPosition
position: 114
reference: A0A0D4E2N9-1

-9218585569269406674tt134
type: Position
type: ExactPosition
position: 134
reference: A0A0D4E2N9-1

SIP86249164C211B769
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt141tt159

-9218585569269406674tt141
type: Position
type: ExactPosition
position: 141
reference: A0A0D4E2N9-1

-9218585569269406674tt159
type: Position
type: ExactPosition
position: 159
reference: A0A0D4E2N9-1

SIP9ABD6A7A09D0EA83
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt179tt201

-9218585569269406674tt179
type: Position
type: ExactPosition
position: 179
reference: A0A0D4E2N9-1

-9218585569269406674tt201
type: Position
type: ExactPosition
position: 201
reference: A0A0D4E2N9-1

SIP2F49D6AC3161159E
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt230tt251

-9218585569269406674tt230
type: Position
type: ExactPosition
position: 230
reference: A0A0D4E2N9-1

-9218585569269406674tt251
type: Position
type: ExactPosition
position: 251
reference: A0A0D4E2N9-1

SIP0670C077384E176E
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt289tt309

-9218585569269406674tt289
type: Position
type: ExactPosition
position: 289
reference: A0A0D4E2N9-1

-9218585569269406674tt309
type: Position
type: ExactPosition
position: 309
reference: A0A0D4E2N9-1

SIPD2F5415DA3F492C9
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt321tt341

-9218585569269406674tt321
type: Position
type: ExactPosition
position: 321
reference: A0A0D4E2N9-1

-9218585569269406674tt341
type: Position
type: ExactPosition
position: 341
reference: A0A0D4E2N9-1

SIP9E7BD379B2070953
type: Transmembrane Annotation
comment: Helical
range: -9218585569269406674tt347tt370

-9218585569269406674tt347
type: Position
type: ExactPosition
position: 347
reference: A0A0D4E2N9-1

-9218585569269406674tt370
type: Position
type: ExactPosition
position: 370
reference: A0A0D4E2N9-1

SIP3CDB5E0F5D217105
type: Domain Extent Annotation
comment: CYTB_NTER
range: -9218585569269406674tt1tt210

-9218585569269406674tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0D4E2N9-1

-9218585569269406674tt210
type: Position
type: ExactPosition
position: 210
reference: A0A0D4E2N9-1

SIPF84709301F8938D0
type: Domain Extent Annotation
comment: CYTB_CTER
range: -9218585569269406674tt211tt380

-9218585569269406674tt211
type: Position
type: ExactPosition
position: 211
reference: A0A0D4E2N9-1

-9218585569269406674tt380
type: Position
type: ExactPosition
position: 380
reference: A0A0D4E2N9-1

SIP4B07F1B3FB73E375
type: Binding Site Annotation
comment: axial binding residue
ligand: b562
ligand part: SIP3DC6E50EC00A509E
range: -9218585569269406674tt84tt84

-9218585569269406674tt84
type: Position
type: ExactPosition
position: 84
reference: A0A0D4E2N9-1

SIP23DA1583935298E3
type: Binding Site Annotation
comment: axial binding residue
ligand: b566
ligand part: SIPDEA17CD1404F7F17
range: -9218585569269406674tt98tt98

-9218585569269406674tt98
type: Position
type: ExactPosition
position: 98
reference: A0A0D4E2N9-1

SIPEE6A48C31B27A6A3
type: Binding Site Annotation
comment: axial binding residue
ligand: b562
ligand part: SIP3DC6E50EC00A509E
range: -9218585569269406674tt183tt183

-9218585569269406674tt183
type: Position
type: ExactPosition
position: 183
reference: A0A0D4E2N9-1

SIPF03456BC2424C87B
type: Binding Site Annotation
comment: axial binding residue
ligand: b566
ligand part: SIPDEA17CD1404F7F17
range: -9218585569269406674tt197tt197

-9218585569269406674tt197
type: Position
type: ExactPosition
position: 197
reference: A0A0D4E2N9-1

-9218585569269406674tt202
type: Position
type: ExactPosition
position: 202
reference: A0A0D4E2N9-1

b562
subclass of: CHEBI_60344

b566
subclass of: CHEBI_60344

A0A0D4E2N9-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 42525
value: MALNLRKNHPLLKIINNSLIDLPTPSNISAWWNFGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWLWGGFSVDNPTLTRFFAFHFILPFVIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSIKDLLGFALMIIPLITLALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLIPFLHVSKQRSMTFRPLSQILFWTLVADLLILTWVGSQPVEHPFIIIGQLASFTYFAIILILFPIVSALENKMLKL

http://purl.uniprot.org/uniprot/A0A0D4E250
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 31
mnemonic: A0A0D4E250_CORHA
citation: SIP45F7528490734893
recommended name: SIP43EA97D6E21C37A3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP853691BDECE738F7
annotation: SIPB4870D4C1C190B51
annotation: SIP743D17AC655D5402
annotation: SIPF283E8EDB40BFCC9
annotation: SIP2DEE126A45AA0815
annotation: SIP716E64314D48FA72
annotation: SIP4FC06F9136BFFF74
annotation: SIPDAF56E65BE315D3B
annotation: SIP9516B0BEFE936473
annotation: SIPD727E43371482F56
annotation: SIP95815D4494025782
annotation: SIPFCC0384957573C8B
annotation: SIP3A52F0C4FF6EE80A
annotation: SIP75849212AA6995F7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0006120
sequence: http://purl.uniprot.org/isoforms/A0A0D4E250-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR010933
type: Resource
database: InterPro
comment: NADH_DH_su2_C

IPR003917
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_chain2

PF06444
type: Resource
database: Pfam
comment: NADH_dehy_S2_C
signature sequence match: Pfam PF06444 match 1

PR01436
type: Resource
database: PRINTS
comment: NADHDHGNASE2

SIP43EA97D6E21C37A3
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 2
ec name: 7.1.1.2

NADH2
type: Gene

SIP853691BDECE738F7
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIPF283E8EDB40BFCC9
type: Similarity Annotation
comment: Belongs to the complex I subunit 2 family.

SIP2DEE126A45AA0815
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt56tt75

-9218585569269825490tt56
type: Position
type: ExactPosition
position: 56
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt75
type: Position
type: ExactPosition
position: 75
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIP716E64314D48FA72
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt95tt115

-9218585569269825490tt95
type: Position
type: ExactPosition
position: 95
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt115
type: Position
type: ExactPosition
position: 115
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIP4FC06F9136BFFF74
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt152tt171

-9218585569269825490tt152
type: Position
type: ExactPosition
position: 152
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt171
type: Position
type: ExactPosition
position: 171
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIPDAF56E65BE315D3B
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt178tt197

-9218585569269825490tt178
type: Position
type: ExactPosition
position: 178
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt197
type: Position
type: ExactPosition
position: 197
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIP9516B0BEFE936473
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt203tt222

-9218585569269825490tt203
type: Position
type: ExactPosition
position: 203
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt222
type: Position
type: ExactPosition
position: 222
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIPD727E43371482F56
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt243tt267

-9218585569269825490tt243
type: Position
type: ExactPosition
position: 243
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt267
type: Position
type: ExactPosition
position: 267
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIP95815D4494025782
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt279tt304

-9218585569269825490tt279
type: Position
type: ExactPosition
position: 279
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt304
type: Position
type: ExactPosition
position: 304
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIPFCC0384957573C8B
type: Transmembrane Annotation
comment: Helical
range: -9218585569269825490tt325tt345

-9218585569269825490tt325
type: Position
type: ExactPosition
position: 325
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt345
type: Position
type: ExactPosition
position: 345
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIP3A52F0C4FF6EE80A
type: Domain Extent Annotation
comment: Proton_antipo_M
range: -9218585569269825490tt23tt288

-9218585569269825490tt23
type: Position
type: ExactPosition
position: 23
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt288
type: Position
type: ExactPosition
position: 288
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

SIP75849212AA6995F7
type: Domain Extent Annotation
comment: NADH_dehy_S2_C
range: -9218585569269825490tt290tt343

-9218585569269825490tt290
type: Position
type: ExactPosition
position: 290
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

-9218585569269825490tt343
type: Position
type: ExactPosition
position: 343
reference: http://purl.uniprot.org/isoforms/A0A0D4E250-1

http://purl.uniprot.org/isoforms/A0A0D4E250-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 38234
value: MNPQAKLIFVTSLLLGTTITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQATASTLVLFSSMTNAWYTGQWDITQMTHPTSSLILTAAISMKLGLVPFHFWFPEVLQGSPLITGLLLSTVMKFPPITLLYMTSLSLNPALLTTLAILSVALGGWMGLNQTQTRKIMAFSSISHLGWMAIILIYYPKLTLLNFYLYAMMTAAVFLTLNSMKVLNLSTLMTAWTKAPSLSTILLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPTAIIISLLSLLSLFFYLRLAYCATITLPPHTTNHMKQWHTNKPINSSIAVLTTLSIMLLPASPMLITII

A0A0D4E2P4
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 38
mnemonic: A0A0D4E2P4_CORHA
citation: SIP45F7528490734893
recommended name: SIP1B9C7925A4D98EBA
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIPB28497BDECDA4328
annotation: SIP763AA1B6B7AF5B69
annotation: SIPBA0D1F7EA923A205
annotation: SIPAD4778894492D61D
annotation: SIP96294CF0B9CC8284
annotation: SIP1552034A0C034286
annotation: SIPB6FD10C76F358979
annotation: SIP246E653EFF8B19BA
annotation: SIP7C2F5AF44B5BBA2C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0005507
classified with: GO_0004129
sequence: A0A0D4E2P4-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

cd13912
type: Resource
database: CDD
comment: CcO_II_C
signature sequence match: CDD cd13912 match 1

IPR045187
type: Resource
database: InterPro
comment: CcO_II

IPR002429
type: Resource
database: InterPro
comment: CcO_II-like_C

IPR034210
type: Resource
database: InterPro
comment: CcO_II_C

IPR001505
type: Resource
database: InterPro
comment: Copper_CuA

IPR008972
type: Resource
database: InterPro
comment: Cupredoxin

IPR014222
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su2

IPR011759
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su2_TM_dom

IPR036257
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su2_TM_sf

PTHR22888
type: Resource
database: PANTHER
comment: CYTOCHROME C OXIDASE, SUBUNIT II
signature sequence match: PANTHER PTHR22888 match 1

PF00116
type: Resource
database: Pfam
comment: COX2
signature sequence match: Pfam PF00116 match 1

PF02790
type: Resource
database: Pfam
comment: COX2_TM
signature sequence match: Pfam PF02790 match 1

SSF49503
type: Resource
database: SUPFAM
comment: Cupredoxins
signature sequence match: SUPFAM SSF49503 match 1

SSF81464
type: Resource
database: SUPFAM
comment: Cytochrome c oxidase subunit II-like, transmembrane region
signature sequence match: SUPFAM SSF81464 match 1

TIGR02866
type: Resource
database: TIGRFAMs
comment: CoxB
signature sequence match: TIGRFAMs TIGR02866 match 1

PS00078
type: Resource
database: PROSITE
comment: COX2
signature sequence match: PROSITE PS00078 match 1

PS50857
type: Resource
database: PROSITE
comment: COX2_CUA
signature sequence match: PROSITE PS50857 match 1

PS50999
type: Resource
database: PROSITE
comment: COX2_TM
signature sequence match: PROSITE PS50999 match 1

SIP1B9C7925A4D98EBA
type: Structured Name
full name: Cytochrome c oxidase subunit 2

COII
type: Gene

SIPB28497BDECDA4328
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPBA0D1F7EA923A205
type: Cofactor Annotation
comment: Binds a copper A center.
cofactor: CHEBI_23378

SIP96294CF0B9CC8284
type: Similarity Annotation
comment: Belongs to the cytochrome c oxidase subunit 2 family.

SIP1552034A0C034286
type: Transmembrane Annotation
comment: Helical
range: -9218585569269379026tt23tt42

-9218585569269379026tt23
type: Position
type: ExactPosition
position: 23
reference: A0A0D4E2P4-1

-9218585569269379026tt42
type: Position
type: ExactPosition
position: 42
reference: A0A0D4E2P4-1

SIPB6FD10C76F358979
type: Transmembrane Annotation
comment: Helical
range: -9218585569269379026tt62tt84

-9218585569269379026tt62
type: Position
type: ExactPosition
position: 62
reference: A0A0D4E2P4-1

-9218585569269379026tt84
type: Position
type: ExactPosition
position: 84
reference: A0A0D4E2P4-1

SIP246E653EFF8B19BA
type: Domain Extent Annotation
comment: COX2_TM
range: -9218585569269379026tt1tt90

-9218585569269379026tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0D4E2P4-1

-9218585569269379026tt90
type: Position
type: ExactPosition
position: 90
reference: A0A0D4E2P4-1

SIP7C2F5AF44B5BBA2C
type: Domain Extent Annotation
comment: COX2_CUA
range: -9218585569269379026tt91tt224

-9218585569269379026tt91
type: Position
type: ExactPosition
position: 91
reference: A0A0D4E2P4-1

-9218585569269379026tt224
type: Position
type: ExactPosition
position: 224
reference: A0A0D4E2P4-1

A0A0D4E2P4-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 25404
value: MANHMQFGFQDASSPIMEELVEFHDHALMTALAICSLVLYLLTTMLTEKLSSSTVDAQEIELVWTILPAAVLIMLALPSLRILYMMDEINEPDLTLKAIGHQWYWTYEYTDFKDLTFDSYMTPTADLPLGHFRLLEVDHRAVVPMESLVRVIVTADDVLHSWAVPSLGVKTDAIPGRLNQTSFTATRPGVFYGQCSEICGANHSFMPIVVESAPLADFENWSSLLSS

http://purl.uniprot.org/uniprot/A0A0D4E319
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 24
mnemonic: A0A0D4E319_CORHA
citation: SIP45F7528490734893
recommended name: SIP7BF6D4C4FDB5C391
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIPF460DBEABC0A8DF4
annotation: SIPF0E5D66B0470ACB1
annotation: SIP39FA12DD5CA6129C
annotation: SIPCC00D82AE2D44418
annotation: SIP5D5B458749B29C4F
annotation: PRO_5010907831
annotation: SIP1BFD46808E7BA1BC
annotation: SIP81F4117C4375FC69
annotation: SIPFCAD9ED1BF1C5859
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/732
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0031966
classified with: GO_0070469
classified with: GO_0008137
sequence: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR001457
type: Resource
database: InterPro
comment: NADH_UbQ/plastoQ_OxRdtase_su6

IPR042106
type: Resource
database: InterPro
comment: Nuo/plastoQ_OxRdtase_6_NuoJ

PF00499
type: Resource
database: Pfam
comment: Oxidored_q3
signature sequence match: Pfam PF00499 match 1

SIP7BF6D4C4FDB5C391
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 6
ec name: 7.1.1.2

NADH6
type: Gene

SIPF460DBEABC0A8DF4
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIPCC00D82AE2D44418
type: Similarity Annotation
comment: Belongs to the complex I subunit 6 family.

-9218585569268833234tt1
type: Position
type: ExactPosition
position: 1
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

-9218585569268833234tt20
type: Position
type: ExactPosition
position: 20
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

PRO_5010907831
type: Chain Annotation
comment: NADH-ubiquinone oxidoreductase chain 6
mass: 15891
range: -9218585569268833234tt21tt173

-9218585569268833234tt21
type: Position
type: ExactPosition
position: 21
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

-9218585569268833234tt173
type: Position
type: ExactPosition
position: 173
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

SIP1BFD46808E7BA1BC
type: Transmembrane Annotation
comment: Helical
range: -9218585569268833234tt44tt75

-9218585569268833234tt44
type: Position
type: ExactPosition
position: 44
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

-9218585569268833234tt75
type: Position
type: ExactPosition
position: 75
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

SIP81F4117C4375FC69
type: Transmembrane Annotation
comment: Helical
range: -9218585569268833234tt87tt108

-9218585569268833234tt87
type: Position
type: ExactPosition
position: 87
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

-9218585569268833234tt108
type: Position
type: ExactPosition
position: 108
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

SIPFCAD9ED1BF1C5859
type: Transmembrane Annotation
comment: Helical
range: -9218585569268833234tt142tt162

-9218585569268833234tt142
type: Position
type: ExactPosition
position: 142
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

-9218585569268833234tt162
type: Position
type: ExactPosition
position: 162
reference: MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV

MMNFVLFMSLCFVLGGLAVASNPSPYYGVVGLVVASIAGCGWLVSMGVSFISLVLVMVYLGGMLVVFVYSVSLAADPYPESWGDWRVVGYGVGMGLVVVIVGVVTGAFSEVVMGGDTVNNGGLSWIRTDFSGVAMFYSSGSGLLLIAGWGLLLTLFVVLELVRGLSRGAIRAV
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 18036

http://purl.uniprot.org/uniprot/A0A0D4E2D3
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 24
mnemonic: A0A0D4E2D3_CORHA
citation: SIP45F7528490734893
recommended name: SIPC3FAAD39E4A0A720
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIPA850635D484B9F85
annotation: SIP8D448F6B75FBDFB8
annotation: SIPF3CA3994E37A1932
annotation: SIP721482C222BF400A
annotation: SIP856817A28BEB61FD
annotation: SIP53612D9385852C89
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0042773
sequence: MSALQLSFFSAFTLSSLGLAFHRTHLISALLCLESMMLSMYIALSMWPIQTQTTSATLLPLLMLAFSACEAATGLALLVASTRTHGSDHLHNFNLLQC

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR001133
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_chain4L/K

IPR039428
type: Resource
database: InterPro
comment: NUOK/Mnh_C1-like

PTHR11434
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L
signature sequence match: PANTHER PTHR11434 match 1

PF00420
type: Resource
database: Pfam
comment: Oxidored_q2
signature sequence match: Pfam PF00420 match 1

SIPC3FAAD39E4A0A720
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 4L
ec name: 7.1.1.2

NADH4L
type: Gene

SIPA850635D484B9F85
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

SIP721482C222BF400A
type: Similarity Annotation
comment: Belongs to the complex I subunit 4L family.

SIP856817A28BEB61FD
type: Transmembrane Annotation
comment: Helical
range: -9218585569269576658tt28tt49

-9218585569269576658tt28
type: Position
type: ExactPosition
position: 28
reference: MSALQLSFFSAFTLSSLGLAFHRTHLISALLCLESMMLSMYIALSMWPIQTQTTSATLLPLLMLAFSACEAATGLALLVASTRTHGSDHLHNFNLLQC

-9218585569269576658tt49
type: Position
type: ExactPosition
position: 49
reference: MSALQLSFFSAFTLSSLGLAFHRTHLISALLCLESMMLSMYIALSMWPIQTQTTSATLLPLLMLAFSACEAATGLALLVASTRTHGSDHLHNFNLLQC

SIP53612D9385852C89
type: Transmembrane Annotation
comment: Helical
range: -9218585569269576658tt61tt80

-9218585569269576658tt61
type: Position
type: ExactPosition
position: 61
reference: MSALQLSFFSAFTLSSLGLAFHRTHLISALLCLESMMLSMYIALSMWPIQTQTTSATLLPLLMLAFSACEAATGLALLVASTRTHGSDHLHNFNLLQC

-9218585569269576658tt80
type: Position
type: ExactPosition
position: 80
reference: MSALQLSFFSAFTLSSLGLAFHRTHLISALLCLESMMLSMYIALSMWPIQTQTTSATLLPLLMLAFSACEAATGLALLVASTRTHGSDHLHNFNLLQC

MSALQLSFFSAFTLSSLGLAFHRTHLISALLCLESMMLSMYIALSMWPIQTQTTSATLLPLLMLAFSACEAATGLALLVASTRTHGSDHLHNFNLLQC
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 10648

http://purl.uniprot.org/uniprot/A0A0D4E240
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 20
mnemonic: A0A0D4E240_CORHA
citation: SIP45F7528490734893
recommended name: SIP1E250F07EB44E932
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP64F431D0AB5D62B9
annotation: SIPBDEA724E7AD5DE98
annotation: SIPD629DE1AA8166711
annotation: SIPD78262167EA036E2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0000276
classified with: GO_0015078
classified with: GO_0015986
sequence: MPQLNPNPWFFIMLTSWLTYSMIIQPKLLSFISMNPPLSKTQTTLTTSPWTWPWT

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR001421
type: Resource
database: InterPro
comment: ATP8_metazoa

PF00895
type: Resource
database: Pfam
comment: ATP-synt_8
signature sequence match: Pfam PF00895 match 1

SIP1E250F07EB44E932
type: Structured Name
full name: ATP synthase protein 8

ATP8
type: Gene

SIP64F431D0AB5D62B9
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.

SIPD629DE1AA8166711
type: Similarity Annotation
comment: Belongs to the ATPase protein 8 family.

SIPD78262167EA036E2
type: Transmembrane Annotation
comment: Helical
range: -9218585569269841874tt6tt24

-9218585569269841874tt6
type: Position
type: ExactPosition
position: 6
reference: MPQLNPNPWFFIMLTSWLTYSMIIQPKLLSFISMNPPLSKTQTTLTTSPWTWPWT

-9218585569269841874tt24
type: Position
type: ExactPosition
position: 24
reference: MPQLNPNPWFFIMLTSWLTYSMIIQPKLLSFISMNPPLSKTQTTLTTSPWTWPWT

MPQLNPNPWFFIMLTSWLTYSMIIQPKLLSFISMNPPLSKTQTTLTTSPWTWPWT
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 6516

http://purl.uniprot.org/uniprot/A0A0D4E315
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 27
mnemonic: A0A0D4E315_CORHA
citation: SIP45F7528490734893
recommended name: SIP0691DD681D8B27AA
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIPB09FD7B787BE982C
annotation: SIP2AE95DF36F0FBAE4
annotation: SIP4BC98EC383E9398F
annotation: SIPE67D11B2122D6756
annotation: SIP6365C32BF4B088FD
annotation: PRO_5010907833
annotation: SIP94978CFA19249871
annotation: SIPC572D566DE09AF39
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/732
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0031966
classified with: GO_0070469
classified with: GO_0008137
sequence: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

SB40
type: Strain

IPR000440
type: Resource
database: InterPro
comment: NADH_UbQ/plastoQ_OxRdtase_su3

IPR038430
type: Resource
database: InterPro
comment: NDAH_ubi_oxred_su3_sf

PTHR11058
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3
signature sequence match: PANTHER PTHR11058 match 1

PF00507
type: Resource
database: Pfam
comment: Oxidored_q4
signature sequence match: Pfam PF00507 match 1

SIP0691DD681D8B27AA
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 3
ec name: 7.1.1.2

NADH3
type: Gene

SIPB09FD7B787BE982C
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.

SIPE67D11B2122D6756
type: Similarity Annotation
comment: Belongs to the complex I subunit 3 family.

-9218585569268837330tt1
type: Position
type: ExactPosition
position: 1
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

-9218585569268837330tt26
type: Position
type: ExactPosition
position: 26
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

PRO_5010907833
type: Chain Annotation
comment: NADH-ubiquinone oxidoreductase chain 3
mass: 10243
range: -9218585569268837330tt27tt116

-9218585569268837330tt27
type: Position
type: ExactPosition
position: 27
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

-9218585569268837330tt116
type: Position
type: ExactPosition
position: 116
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

SIP94978CFA19249871
type: Transmembrane Annotation
comment: Helical
range: -9218585569268837330tt52tt76

-9218585569268837330tt52
type: Position
type: ExactPosition
position: 52
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

-9218585569268837330tt76
type: Position
type: ExactPosition
position: 76
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

SIPC572D566DE09AF39
type: Transmembrane Annotation
comment: Helical
range: -9218585569268837330tt88tt107

-9218585569268837330tt88
type: Position
type: ExactPosition
position: 88
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

-9218585569268837330tt107
type: Position
type: ExactPosition
position: 107
reference: MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE

MNMILFMMASSLILSVILTALNFWLAQMNPDSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAMQLQTPTTTLTWSSILILLLTLGLIYEWNQGGLEWAE
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 13170

Q9G3J8
type: Protein
reviewed: false
created: 2001-03-01
modified: 2022-12-14
version: 71
mnemonic: Q9G3J8_CORHA
citation: http://purl.uniprot.org/citations/11197122
recommended name: SIP04BB22F94509478D
alternative name: SIP70174F4CDEA2B1F1
alternative name: SIP96AAF15ABE9D3699
alternative name: SIPB3185EE1AF674321
alternative name: SIPC22CFE0E4256EEDB
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP457A5D19985571B1
annotation: SIP80B56A6B42C937BC
annotation: SIPD9B15D207104F953
annotation: SIPB59EC0127A63F85A
annotation: SIP534D92595459367E
annotation: SIP9EF09054EF882AF4
annotation: SIP0C20FED2497F98FB
existence: Predicted Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0009055
classified with: GO_0022904
sequence: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

http://purl.uniprot.org/citations/11197122
type: Journal Citation
title: Cryptic genetic variation and paraphyly in ravens.
author: Omland K.E.
author: Tarr C.L.
author: Boarman W.I.
author: Marzluff J.M.
author: Fleischer R.C.
primary topic of: https://pubmed.ncbi.nlm.nih.gov/11197122
date: 2000
name: Proc. R. Soc. B
volume: 267
pages: 2475-2482

Q9G3J8-citation-11197122
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP04BB22F94509478D
type: Structured Name
full name: Cytochrome b

SIP70174F4CDEA2B1F1
type: Structured Name
full name: Complex III subunit 3

SIP96AAF15ABE9D3699
type: Structured Name
full name: Complex III subunit III

SIPB3185EE1AF674321
type: Structured Name
full name: Cytochrome b-c1 complex subunit 3

SIPC22CFE0E4256EEDB
type: Structured Name
full name: Ubiquinol-cytochrome-c reductase complex cytochrome b subunit

cytb
type: Gene

SIP457A5D19985571B1
type: Function Annotation
comment: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

SIPD9B15D207104F953
type: Transmembrane Annotation
comment: Helical
range: 22862451079526446tt54tt71

22862451079526446tt54
type: Position
type: ExactPosition
position: 54
reference: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

22862451079526446tt71
type: Position
type: ExactPosition
position: 71
reference: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

SIPB59EC0127A63F85A
type: Transmembrane Annotation
comment: Helical
range: 22862451079526446tt83tt101

22862451079526446tt83
type: Position
type: ExactPosition
position: 83
reference: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

22862451079526446tt101
type: Position
type: ExactPosition
position: 101
reference: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

SIP534D92595459367E
type: Domain Extent Annotation
comment: CYTB_NTER
range: 22862451079526446tt1tt102

22862451079526446tt1
type: Position
type: ExactPosition
position: 1
reference: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

22862451079526446tt102
type: Position
type: ExactPosition
position: 102
reference: FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP

FGSLLGLCLTVQIITGLLLAMHYTADTSLAFTSVAHTCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKKTWNIGVILLLTLMATAFVGYVLP
type: Simple Sequence
modified: 2001-03-01
version: 1
fragment: single
mass: 11306

http://purl.uniprot.org/uniprot/A0A0D4E254
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 22
mnemonic: A0A0D4E254_CORHA
citation: SIP45F7528490734893
recommended name: SIP63E3671E8FBB9F10
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIPC6BB4E3790213BDC
annotation: SIP31994BD907CD611A
annotation: SIP29C172204A1E223E
annotation: SIPD4A0A0271C8ECB37
annotation: SIP57D5EE3AFA9F992F
annotation: SIP99A15A6218CC7D29
annotation: SIP7F5E0F4B110AB818
annotation: SIPC03D5077D7012F72
annotation: SIP1291FCB48E661168
annotation: SIPD33ECA7508A64C92
annotation: SIPFD888E7388E2C90D
annotation: SIP8858BB8D8E37572E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0016020
classified with: GO_0005739
classified with: GO_0004129
classified with: GO_0019646
sequence: http://purl.uniprot.org/isoforms/A0A0D4E254-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB33
type: Strain

cd01665
type: Resource
database: CDD
comment: Cyt_c_Oxidase_III
signature sequence match: CDD cd01665 match 1

IPR024791
type: Resource
database: InterPro
comment: Cyt_c/ubiquinol_Oxase_su3

IPR033945
type: Resource
database: InterPro
comment: Cyt_c_oxase_su3_dom

IPR000298
type: Resource
database: InterPro
comment: Cyt_c_oxidase-like_su3

IPR035973
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su3-like_sf

IPR013833
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su3_a-hlx

PTHR11403
type: Resource
database: PANTHER
comment: CYTOCHROME C OXIDASE SUBUNIT III
signature sequence match: PANTHER PTHR11403 match 1

PF00510
type: Resource
database: Pfam
comment: COX3
signature sequence match: Pfam PF00510 match 1

SSF81452
type: Resource
database: SUPFAM
comment: Cytochrome c oxidase subunit III-like
signature sequence match: SUPFAM SSF81452 match 1

PS50253
type: Resource
database: PROSITE
comment: COX3
signature sequence match: PROSITE PS50253 match 1

SIP63E3671E8FBB9F10
type: Structured Name
full name: Cytochrome c oxidase subunit 3

COIII
type: Gene

SIPC6BB4E3790213BDC
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPD4A0A0271C8ECB37
type: Similarity Annotation
comment: Belongs to the cytochrome c oxidase subunit 3 family.

SIP57D5EE3AFA9F992F
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt16tt35

-9218585569269821394tt16
type: Position
type: ExactPosition
position: 16
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt35
type: Position
type: ExactPosition
position: 35
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIP99A15A6218CC7D29
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt41tt58

-9218585569269821394tt41
type: Position
type: ExactPosition
position: 41
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt58
type: Position
type: ExactPosition
position: 58
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIP7F5E0F4B110AB818
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt79tt102

-9218585569269821394tt79
type: Position
type: ExactPosition
position: 79
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt102
type: Position
type: ExactPosition
position: 102
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIPC03D5077D7012F72
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt129tt147

-9218585569269821394tt129
type: Position
type: ExactPosition
position: 129
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt147
type: Position
type: ExactPosition
position: 147
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIP1291FCB48E661168
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt159tt177

-9218585569269821394tt159
type: Position
type: ExactPosition
position: 159
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt177
type: Position
type: ExactPosition
position: 177
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIPD33ECA7508A64C92
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt197tt220

-9218585569269821394tt197
type: Position
type: ExactPosition
position: 197
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt220
type: Position
type: ExactPosition
position: 220
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIPFD888E7388E2C90D
type: Transmembrane Annotation
comment: Helical
range: -9218585569269821394tt240tt260

-9218585569269821394tt240
type: Position
type: ExactPosition
position: 240
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt260
type: Position
type: ExactPosition
position: 260
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

SIP8858BB8D8E37572E
type: Domain Extent Annotation
comment: COX3
range: -9218585569269821394tt4tt261

-9218585569269821394tt4
type: Position
type: ExactPosition
position: 4
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

-9218585569269821394tt261
type: Position
type: ExactPosition
position: 261
reference: http://purl.uniprot.org/isoforms/A0A0D4E254-1

http://purl.uniprot.org/isoforms/A0A0D4E254-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 29677
value: MTHQAHSYHMVDPSPWPILGATAALLTTSGLTMWFHHNSPYLLITGLTSTALVMFQWWRDIIRESTFQGHHTPTVQKGLRYGMVLFITSEAFFFLGFFWAFFHSSLAPTPELGGQWPPVGIKPLNPMDVPLLNTAILLASGVTVTWAHHSIMEANRKQAIHALALTVLLGFYFTGLQAMEYYEAPFSIADGVYGSTFFVATGFHGLHVIIGSTFLLVCLLRLIKYHFTPKHHFGFEAAAWYWHFVDVVWLFLYMTIYWWGS

I3WEC8
type: Protein
reviewed: false
created: 2012-09-05
modified: 2022-12-14
version: 39
mnemonic: I3WEC8_CORHA
citation: http://purl.uniprot.org/citations/22642364
recommended name: SIP43EA97D6E21C37A3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP76314A13E52985A0
annotation: SIP348F2120CDADFEB4
annotation: SIPE7CABE12EB7E74A0
annotation: SIP10E38250869355EC
annotation: SIP5BA491E54C390796
annotation: SIPE2A909EFD5FBD073
annotation: SIPDC5C3FDC08A9B8F1
annotation: SIP39560496AF5D933D
annotation: SIP86FF4096D2BF7836
annotation: SIP21D20870F06B74E5
annotation: SIP04BBDD69917934FD
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0006120
sequence: I3WEC8-1

http://purl.uniprot.org/citations/22642364
type: Journal Citation
title: Brains, tools, innovation and biogeography in crows and ravens.
author: Jonsson K.A.
author: Fabre P.H.
author: Irestedt M.
primary topic of: https://pubmed.ncbi.nlm.nih.gov/22642364
date: 2012
name: BMC Evol. Biol.
volume: 12
pages: 72

I3WEC8-citation-22642364
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP43EA97D6E21C37A3
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 2
ec name: 7.1.1.2

ND2
type: Gene

SIP76314A13E52985A0
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIP10E38250869355EC
type: Similarity Annotation
comment: Belongs to the complex I subunit 2 family.

SIP5BA491E54C390796
type: Caution Annotation
comment: Lacks conserved residue(s) required for the propagation of feature annotation.

SIPE2A909EFD5FBD073
type: Transmembrane Annotation
comment: Helical
range: 20604123217082414tt243tt266

20604123217082414tt243
type: Position
type: ExactPosition
position: 243
reference: I3WEC8-1

20604123217082414tt266
type: Position
type: ExactPosition
position: 266
reference: I3WEC8-1

SIPDC5C3FDC08A9B8F1
type: Transmembrane Annotation
comment: Helical
range: 20604123217082414tt278tt304

20604123217082414tt278
type: Position
type: ExactPosition
position: 278
reference: I3WEC8-1

20604123217082414tt304
type: Position
type: ExactPosition
position: 304
reference: I3WEC8-1

SIP39560496AF5D933D
type: Transmembrane Annotation
comment: Helical
range: 20604123217082414tt324tt345

20604123217082414tt324
type: Position
type: ExactPosition
position: 324
reference: I3WEC8-1

20604123217082414tt345
type: Position
type: ExactPosition
position: 345
reference: I3WEC8-1

SIP86FF4096D2BF7836
type: Domain Extent Annotation
comment: Proton_antipo_M
range: 20604123217082414tt23tt112

20604123217082414tt23
type: Position
type: ExactPosition
position: 23
reference: I3WEC8-1

20604123217082414tt112
type: Position
type: ExactPosition
position: 112
reference: I3WEC8-1

SIP21D20870F06B74E5
type: Domain Extent Annotation
comment: Proton_antipo_M
range: 20604123217082414tt237tt288

20604123217082414tt237
type: Position
type: ExactPosition
position: 237
reference: I3WEC8-1

20604123217082414tt288
type: Position
type: ExactPosition
position: 288
reference: I3WEC8-1

SIP04BBDD69917934FD
type: Domain Extent Annotation
comment: NADH_dehy_S2_C
range: 20604123217082414tt290tt343

20604123217082414tt290
type: Position
type: ExactPosition
position: 290
reference: I3WEC8-1

20604123217082414tt343
type: Position
type: ExactPosition
position: 343
reference: I3WEC8-1

I3WEC8-1
type: Simple Sequence
modified: 2012-09-05
version: 1
mass: 38220
value: MNPQAKLIFVTSLLLGTTITISSNHWIMAWTGLEINTLAILPLISKSHHPRAIEAATKYFMVQATASTLVLFSSMTNAWYTGQWDITQMTHPTSSLILTAAISMKLGLVPFHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPSLSTILLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPTAIIISLLSLLSLFFYLRLAYCATITLPPHTTNHMKQWHTNKPINSSIAVLTTLSIMLLPASPMLITII

A0A0D4E2N4
type: Protein
reviewed: false
created: 2015-05-27
modified: 2022-12-14
version: 19
mnemonic: A0A0D4E2N4_CORHA
citation: SIP45F7528490734893
recommended name: SIP63E3671E8FBB9F10
organism: http://purl.uniprot.org/taxonomy/134902
encoded in: Mitochondrion
annotation: SIP129F83CF46203539
annotation: SIP3788CB544034D86C
annotation: SIP9FDDF6DC6069F039
annotation: SIPCFB67CD351B649A8
annotation: SIP4370EBA0A33E8C2F
annotation: SIP13992EC66DC25960
annotation: SIP42E18742A936832B
annotation: SIPA92EB7AC3F87F603
annotation: SIPF10B888464EC9A31
annotation: SIP56F459A7AAEB849C
annotation: SIP90D3E6C0E486D267
annotation: SIPB731DC7744F971EC
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0016020
classified with: GO_0005739
classified with: GO_0004129
classified with: GO_0019646
sequence: A0A0D4E2N4-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SB40
type: Strain

SIP63E3671E8FBB9F10
type: Structured Name
full name: Cytochrome c oxidase subunit 3

COIII
type: Gene

SIP129F83CF46203539
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPCFB67CD351B649A8
type: Similarity Annotation
comment: Belongs to the cytochrome c oxidase subunit 3 family.

SIP4370EBA0A33E8C2F
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt16tt35

-9218585569269411794tt16
type: Position
type: ExactPosition
position: 16
reference: A0A0D4E2N4-1

-9218585569269411794tt35
type: Position
type: ExactPosition
position: 35
reference: A0A0D4E2N4-1

SIP13992EC66DC25960
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt41tt58

-9218585569269411794tt41
type: Position
type: ExactPosition
position: 41
reference: A0A0D4E2N4-1

-9218585569269411794tt58
type: Position
type: ExactPosition
position: 58
reference: A0A0D4E2N4-1

SIP42E18742A936832B
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt79tt102

-9218585569269411794tt79
type: Position
type: ExactPosition
position: 79
reference: A0A0D4E2N4-1

-9218585569269411794tt102
type: Position
type: ExactPosition
position: 102
reference: A0A0D4E2N4-1

SIPA92EB7AC3F87F603
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt129tt147

-9218585569269411794tt129
type: Position
type: ExactPosition
position: 129
reference: A0A0D4E2N4-1

-9218585569269411794tt147
type: Position
type: ExactPosition
position: 147
reference: A0A0D4E2N4-1

SIPF10B888464EC9A31
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt159tt177

-9218585569269411794tt159
type: Position
type: ExactPosition
position: 159
reference: A0A0D4E2N4-1

-9218585569269411794tt177
type: Position
type: ExactPosition
position: 177
reference: A0A0D4E2N4-1

SIP56F459A7AAEB849C
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt197tt220

-9218585569269411794tt197
type: Position
type: ExactPosition
position: 197
reference: A0A0D4E2N4-1

-9218585569269411794tt220
type: Position
type: ExactPosition
position: 220
reference: A0A0D4E2N4-1

SIP90D3E6C0E486D267
type: Transmembrane Annotation
comment: Helical
range: -9218585569269411794tt240tt260

-9218585569269411794tt240
type: Position
type: ExactPosition
position: 240
reference: A0A0D4E2N4-1

-9218585569269411794tt260
type: Position
type: ExactPosition
position: 260
reference: A0A0D4E2N4-1

SIPB731DC7744F971EC
type: Domain Extent Annotation
comment: COX3
range: -9218585569269411794tt4tt261

-9218585569269411794tt4
type: Position
type: ExactPosition
position: 4
reference: A0A0D4E2N4-1

-9218585569269411794tt261
type: Position
type: ExactPosition
position: 261
reference: A0A0D4E2N4-1

A0A0D4E2N4-1
type: Simple Sequence
modified: 2015-05-27
version: 1
mass: 29643
value: MTHQAHSYHMVDPSPWPILGATAALLTTSGLTMWLHHNSPYLLITGLTSTALVMFQWWRDIIRESTFQGHHTPTVQKGLRYGMVLFITSEAFFFLGFFWAFFHSSLAPTPELGGQWPPVGIKPLNPMDVPLLNTAILLASGVTVTWAHHSIMEANRKQAIHALALTVLLGFYFTGLQAMEYYEAPFSIADGVYGSTFFVATGFHGLHVIIGSTFLLVCLLRLIKYHFTPKHHFGFEAAAWYWHFVDVVWLFLYMTIYWWGS