S5ZCT5
type: Protein
reviewed: false
created: 2013-10-16
modified: 2022-12-14
version: 38
mnemonic: S5ZCT5_9TELE
citation: http://purl.uniprot.org/citations/22829879
citation: SIP88505CDF186F3E63
recommended name: SIP99F797808497C9B3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.9
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP1EFC71B8ABAA297C
annotation: SIP36D84A6814B62A6E
annotation: SIP76662875D8ACDA1A
annotation: SIP5BCB364C0AF763DC
annotation: SIP0D903C48B4CDA575
annotation: SIP0D68832C806FE4D9
annotation: SIP9525A06627F3D819
annotation: SIPFF86C0A0AD9E282E
annotation: SIP4B8D1A4BEDF628D6
annotation: SIPD8534A6225FA4C26
annotation: SIPDAB3DD70876250B4
annotation: SIPD6297C5CD896E9E3
annotation: SIP70F3FCF6FE8EAA18
annotation: SIPBCEF5C1F05FF227E
annotation: SIP03A94EA6287B44D0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/915
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0004129
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0006119
sequence: S5ZCT5-1

http://purl.uniprot.org/citations/22829879
type: Journal Citation
title: Cryptic diversity in Indo-Australian rainbowfishes revealed by DNA barcoding: implications for conservation in a biodiversity hotspot candidate.
author: Kadarusman
author: Hubert N.
author: Hadiaty R.K.
author: Sudarto
author: Paradis E.
author: Pouyaud L.
primary topic of: https://pubmed.ncbi.nlm.nih.gov/22829879
date: 2012
name: PLoS ONE
volume: 7
pages: E40627

S5ZCT5-citation-22829879
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP88505CDF186F3E63
type: Submission Citation
author: Hubert N.
author: Hadiaty R.K.
author: Paradis E.
author: Pouyaud L.
date: 2013-08
submitted to: EMBL/GenBank/DDBJ

S5ZCT5-citation-SIP88505CDF186F3E63
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR023616
type: Resource
database: InterPro
comment: Cyt_c_oxase-like_su1_dom

IPR036927
type: Resource
database: InterPro
comment: Cyt_c_oxase-like_su1_sf

IPR000883
type: Resource
database: InterPro
comment: Cyt_C_Oxase_1

PTHR10422
type: Resource
database: PANTHER
comment: CYTOCHROME C OXIDASE SUBUNIT 1
signature sequence match: PANTHER PTHR10422 match 1

PF00115
type: Resource
database: Pfam
comment: COX1
signature sequence match: Pfam PF00115 match 1

PR01165
type: Resource
database: PRINTS
comment: CYCOXIDASEI

SSF81442
type: Resource
database: SUPFAM
comment: Cytochrome c oxidase subunit I-like
signature sequence match: SUPFAM SSF81442 match 1

PS50855
type: Resource
database: PROSITE
comment: COX1
signature sequence match: PROSITE PS50855 match 1

SIP99F797808497C9B3
type: Structured Name
full name: Cytochrome c oxidase subunit 1
ec name: 7.1.1.9

COI
type: Gene

SIP1EFC71B8ABAA297C
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIP9525A06627F3D819
type: Similarity Annotation
comment: Belongs to the heme-copper respiratory oxidase family.

SIPFF86C0A0AD9E282E
type: Transmembrane Annotation
comment: Helical
range: 23421084859905326tt15tt37

23421084859905326tt15
type: Position
type: ExactPosition
position: 15
reference: S5ZCT5-1

23421084859905326tt37
type: Position
type: ExactPosition
position: 37
reference: S5ZCT5-1

SIP4B8D1A4BEDF628D6
type: Transmembrane Annotation
comment: Helical
range: 23421084859905326tt57tt83

23421084859905326tt57
type: Position
type: ExactPosition
position: 57
reference: S5ZCT5-1

23421084859905326tt83
type: Position
type: ExactPosition
position: 83
reference: S5ZCT5-1

SIPD8534A6225FA4C26
type: Transmembrane Annotation
comment: Helical
range: 23421084859905326tt104tt128

23421084859905326tt104
type: Position
type: ExactPosition
position: 104
reference: S5ZCT5-1

23421084859905326tt128
type: Position
type: ExactPosition
position: 128
reference: S5ZCT5-1

SIPDAB3DD70876250B4
type: Transmembrane Annotation
comment: Helical
range: 23421084859905326tt148tt171

23421084859905326tt148
type: Position
type: ExactPosition
position: 148
reference: S5ZCT5-1

23421084859905326tt171
type: Position
type: ExactPosition
position: 171
reference: S5ZCT5-1

SIPD6297C5CD896E9E3
type: Transmembrane Annotation
comment: Helical
range: 23421084859905326tt183tt210

23421084859905326tt183
type: Position
type: ExactPosition
position: 183
reference: S5ZCT5-1

23421084859905326tt210
type: Position
type: ExactPosition
position: 210
reference: S5ZCT5-1

SIP70F3FCF6FE8EAA18
type: Domain Extent Annotation
comment: COX1
range: 23421084859905326tt1tt217

23421084859905326tt1
type: Position
type: ExactPosition
position: 1
reference: S5ZCT5-1

23421084859905326tt217
type: Position
type: ExactPosition
position: 217
reference: S5ZCT5-1

S5ZCT5-1
type: Simple Sequence
modified: 2013-10-16
version: 1
fragment: single
mass: 23311
value: VMITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGSLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTIINMKPPAISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNT

A0A0P0CDP6
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 32
mnemonic: A0A0P0CDP6_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP1B9C7925A4D98EBA
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP7AD7995F39760484
annotation: SIP4F4B333B0DF2DD80
annotation: SIP208400FE382044AE
annotation: SIP50A48CBD33819156
annotation: SIPFDB406904006244D
annotation: SIPFE1FF4F0A39906B6
annotation: SIPE06463271A1B64D9
annotation: SIPF0A229A70777E5D6
annotation: SIP837B96630AB69AC9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0005507
classified with: GO_0004129
sequence: A0A0P0CDP6-1

http://purl.uniprot.org/citations/26472588
type: Journal Citation
title: The complete mitochondrial genome of Boeseman's rainbowfish (Melanotaenia boesemani Allen & Cross, 1980).
author: Zhao Y.
author: Chen Z.
author: Gao J.
author: Wang L.
author: Li Z.
primary topic of: https://pubmed.ncbi.nlm.nih.gov/26472588
date: 2015
name: Mitochondrial DNA
volume: 1-2

A0A0P0CDP6-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

cd13912
type: Resource
database: CDD
comment: CcO_II_C
signature sequence match: CDD cd13912 match 1

IPR045187
type: Resource
database: InterPro
comment: CcO_II

IPR002429
type: Resource
database: InterPro
comment: CcO_II-like_C

IPR034210
type: Resource
database: InterPro
comment: CcO_II_C

IPR001505
type: Resource
database: InterPro
comment: Copper_CuA

IPR008972
type: Resource
database: InterPro
comment: Cupredoxin

IPR014222
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su2

IPR011759
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su2_TM_dom

IPR036257
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su2_TM_sf

PTHR22888
type: Resource
database: PANTHER
comment: CYTOCHROME C OXIDASE, SUBUNIT II
signature sequence match: PANTHER PTHR22888 match 1

PF00116
type: Resource
database: Pfam
comment: COX2
signature sequence match: Pfam PF00116 match 1

PF02790
type: Resource
database: Pfam
comment: COX2_TM
signature sequence match: Pfam PF02790 match 1

SSF49503
type: Resource
database: SUPFAM
comment: Cupredoxins
signature sequence match: SUPFAM SSF49503 match 1

SSF81464
type: Resource
database: SUPFAM
comment: Cytochrome c oxidase subunit II-like, transmembrane region
signature sequence match: SUPFAM SSF81464 match 1

TIGR02866
type: Resource
database: TIGRFAMs
comment: CoxB
signature sequence match: TIGRFAMs TIGR02866 match 1

PS00078
type: Resource
database: PROSITE
comment: COX2
signature sequence match: PROSITE PS00078 match 1

PS50857
type: Resource
database: PROSITE
comment: COX2_CUA
signature sequence match: PROSITE PS50857 match 1

PS50999
type: Resource
database: PROSITE
comment: COX2_TM
signature sequence match: PROSITE PS50999 match 1

SIP1B9C7925A4D98EBA
type: Structured Name
full name: Cytochrome c oxidase subunit 2

COX2
type: Gene

SIP7AD7995F39760484
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIP208400FE382044AE
type: Cofactor Annotation
comment: Binds a copper A center.
cofactor: CHEBI_23378

SIPFDB406904006244D
type: Similarity Annotation
comment: Belongs to the cytochrome c oxidase subunit 2 family.

SIPFE1FF4F0A39906B6
type: Transmembrane Annotation
comment: Helical
range: -9218584761930868690tt27tt51

-9218584761930868690tt27
type: Position
type: ExactPosition
position: 27
reference: A0A0P0CDP6-1

-9218584761930868690tt51
type: Position
type: ExactPosition
position: 51
reference: A0A0P0CDP6-1

SIPE06463271A1B64D9
type: Transmembrane Annotation
comment: Helical
range: -9218584761930868690tt63tt85

-9218584761930868690tt63
type: Position
type: ExactPosition
position: 63
reference: A0A0P0CDP6-1

-9218584761930868690tt85
type: Position
type: ExactPosition
position: 85
reference: A0A0P0CDP6-1

SIPF0A229A70777E5D6
type: Domain Extent Annotation
comment: COX2_TM
range: -9218584761930868690tt1tt91

-9218584761930868690tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0P0CDP6-1

-9218584761930868690tt91
type: Position
type: ExactPosition
position: 91
reference: A0A0P0CDP6-1

SIP837B96630AB69AC9
type: Domain Extent Annotation
comment: COX2_CUA
range: -9218584761930868690tt92tt225

-9218584761930868690tt92
type: Position
type: ExactPosition
position: 92
reference: A0A0P0CDP6-1

-9218584761930868690tt225
type: Position
type: ExactPosition
position: 225
reference: A0A0P0CDP6-1

A0A0P0CDP6-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 26205
value: MAHPSQLGFQDAASPMMEELLHFHDHALMIIFLISTLVLYIIVAMVTTKLTNKFILDSQEIEIIWTILPAIILILIALPSLRILYLMDEINDPHLTIKAMGHQWYWSYEYTDYEDLMFDSYMIPTQDLAPGQFRLLETDHRMVIPAESPIRVLVSAEDVLHSWAVPSLGVKMDAVPGRLNQTAFITSRPGVFYGQCSEICGANHSFMPIVIEAVPLKHFENWSSLMLQDS

K7WPW5
type: Protein
reviewed: false
created: 2013-02-06
modified: 2022-12-14
version: 39
mnemonic: K7WPW5_9TELE
citation: http://purl.uniprot.org/citations/23313459
recommended name: SIP04BB22F94509478D
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP57B180BDEB5490D6
annotation: SIPC3BBB0760B51B374
annotation: SIP71D154E8DF50438D
annotation: SIPFD3C126728AA2632
annotation: SIPCCE58E9DE22CF9E9
annotation: SIPE2E9348BC37CD3DD
annotation: SIP3B2F144B6067877F
annotation: SIP9A4A812F042DD945
annotation: SIPF7BCECEF87E0B7C3
annotation: SIP51F2FE59A6DB9575
annotation: SIPDE3F1DB50E70DABA
annotation: SIPCD16B227CE00A67D
annotation: SIPC95687F6F854ACA3
annotation: SIPF134AA4E5FBEDBB0
annotation: SIP411F92A5A0210313
annotation: SIP53BBFA2267714151
annotation: SIP008808DA17662CCB
annotation: SIP9CB200F3EBB4EBD9
annotation: SIP6F68150E45A72353
annotation: SIPB8B0F0D2B69E24C7
annotation: SIP5FD87CFF0D5F46D0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0045275
classified with: GO_0046872
classified with: GO_0008121
classified with: GO_0022904
sequence: K7WPW5-1

http://purl.uniprot.org/citations/23313459
type: Journal Citation
title: Phylogeny and biogeography of rainbowfishes (Melanotaeniidae) from Australia and New Guinea.
author: Unmack P.J.
author: Allen G.R.
author: Johnson J.B.
primary topic of: https://pubmed.ncbi.nlm.nih.gov/23313459
date: 2013
name: Mol. Phylogenet. Evol.
volume: 67
pages: 15-27

K7WPW5-citation-23313459
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

Mboes.exGL.1
type: Strain

cd00290
type: Resource
database: CDD
comment: cytochrome_b_C
signature sequence match: CDD cd00290 match 1

cd00284
type: Resource
database: CDD
comment: Cytochrome_b_N
signature sequence match: CDD cd00284 match 1

IPR005798
type: Resource
database: InterPro
comment: Cyt_b/b6_C

IPR036150
type: Resource
database: InterPro
comment: Cyt_b/b6_C_sf

IPR005797
type: Resource
database: InterPro
comment: Cyt_b/b6_N

IPR027387
type: Resource
database: InterPro
comment: Cytb/b6-like_sf

IPR030689
type: Resource
database: InterPro
comment: Cytochrome_b

IPR016174
type: Resource
database: InterPro
comment: Di-haem_cyt_TM

PF00032
type: Resource
database: Pfam
comment: Cytochrom_B_C
signature sequence match: Pfam PF00032 match 1

PF00033
type: Resource
database: Pfam
comment: Cytochrome_B
signature sequence match: Pfam PF00033 match 1

PIRSF038885
type: Resource
database: PIRSF
comment: COB
signature sequence match: PIRSF PIRSF038885 match 1

SSF81648
type: Resource
database: SUPFAM
comment: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
signature sequence match: SUPFAM SSF81648 match 1

SSF81342
type: Resource
database: SUPFAM
comment: Transmembrane di-heme cytochromes
signature sequence match: SUPFAM SSF81342 match 1

PS51003
type: Resource
database: PROSITE
comment: CYTB_CTER
signature sequence match: PROSITE PS51003 match 1

PS51002
type: Resource
database: PROSITE
comment: CYTB_NTER
signature sequence match: PROSITE PS51002 match 1

SIP04BB22F94509478D
type: Structured Name
full name: Cytochrome b

cytb
type: Gene

SIP57B180BDEB5490D6
type: Function Annotation
comment: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

SIPC3BBB0760B51B374
type: Cofactor Annotation
comment: Binds 2 heme groups non-covalently.
cofactor: CHEBI_60344

SIP71D154E8DF50438D
type: Cofactor Annotation
comment: Binds 2 heme groups non-covalently.
cofactor: CHEBI_30413

SIPCCE58E9DE22CF9E9
type: Similarity Annotation
comment: Belongs to the cytochrome b family.

SIPE2E9348BC37CD3DD
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt29tt51

21171471402874158tt29
type: Position
type: ExactPosition
position: 29
reference: K7WPW5-1

21171471402874158tt51
type: Position
type: ExactPosition
position: 51
reference: K7WPW5-1

SIP3B2F144B6067877F
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt87tt107

21171471402874158tt87
type: Position
type: ExactPosition
position: 87
reference: K7WPW5-1

21171471402874158tt107
type: Position
type: ExactPosition
position: 107
reference: K7WPW5-1

SIP9A4A812F042DD945
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt113tt133

21171471402874158tt113
type: Position
type: ExactPosition
position: 113
reference: K7WPW5-1

21171471402874158tt133
type: Position
type: ExactPosition
position: 133
reference: K7WPW5-1

SIPF7BCECEF87E0B7C3
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt145tt166

21171471402874158tt145
type: Position
type: ExactPosition
position: 145
reference: K7WPW5-1

21171471402874158tt166
type: Position
type: ExactPosition
position: 166
reference: K7WPW5-1

SIP51F2FE59A6DB9575
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt178tt200

21171471402874158tt178
type: Position
type: ExactPosition
position: 178
reference: K7WPW5-1

21171471402874158tt200
type: Position
type: ExactPosition
position: 200
reference: K7WPW5-1

SIPDE3F1DB50E70DABA
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt229tt250

21171471402874158tt229
type: Position
type: ExactPosition
position: 229
reference: K7WPW5-1

21171471402874158tt250
type: Position
type: ExactPosition
position: 250
reference: K7WPW5-1

SIPCD16B227CE00A67D
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt288tt308

21171471402874158tt288
type: Position
type: ExactPosition
position: 288
reference: K7WPW5-1

21171471402874158tt308
type: Position
type: ExactPosition
position: 308
reference: K7WPW5-1

SIPC95687F6F854ACA3
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt320tt340

21171471402874158tt320
type: Position
type: ExactPosition
position: 320
reference: K7WPW5-1

21171471402874158tt340
type: Position
type: ExactPosition
position: 340
reference: K7WPW5-1

SIPF134AA4E5FBEDBB0
type: Transmembrane Annotation
comment: Helical
range: 21171471402874158tt346tt366

21171471402874158tt346
type: Position
type: ExactPosition
position: 346
reference: K7WPW5-1

21171471402874158tt366
type: Position
type: ExactPosition
position: 366
reference: K7WPW5-1

SIP411F92A5A0210313
type: Domain Extent Annotation
comment: CYTB_NTER
range: 21171471402874158tt1tt209

21171471402874158tt1
type: Position
type: ExactPosition
position: 1
reference: K7WPW5-1

21171471402874158tt209
type: Position
type: ExactPosition
position: 209
reference: K7WPW5-1

SIP53BBFA2267714151
type: Domain Extent Annotation
comment: CYTB_CTER
range: 21171471402874158tt210tt379

21171471402874158tt210
type: Position
type: ExactPosition
position: 210
reference: K7WPW5-1

21171471402874158tt379
type: Position
type: ExactPosition
position: 379
reference: K7WPW5-1

SIP008808DA17662CCB
type: Binding Site Annotation
comment: axial binding residue
ligand: b562
ligand part: SIP3DC6E50EC00A509E
range: 21171471402874158tt83tt83

21171471402874158tt83
type: Position
type: ExactPosition
position: 83
reference: K7WPW5-1

SIP9CB200F3EBB4EBD9
type: Binding Site Annotation
comment: axial binding residue
ligand: b566
ligand part: SIPDEA17CD1404F7F17
range: 21171471402874158tt97tt97

21171471402874158tt97
type: Position
type: ExactPosition
position: 97
reference: K7WPW5-1

SIP6F68150E45A72353
type: Binding Site Annotation
comment: axial binding residue
ligand: b562
ligand part: SIP3DC6E50EC00A509E
range: 21171471402874158tt182tt182

21171471402874158tt182
type: Position
type: ExactPosition
position: 182
reference: K7WPW5-1

SIPB8B0F0D2B69E24C7
type: Binding Site Annotation
comment: axial binding residue
ligand: b566
ligand part: SIPDEA17CD1404F7F17
range: 21171471402874158tt196tt196

21171471402874158tt196
type: Position
type: ExactPosition
position: 196
reference: K7WPW5-1

21171471402874158tt201
type: Position
type: ExactPosition
position: 201
reference: K7WPW5-1

b562
subclass of: CHEBI_60344

b566
subclass of: CHEBI_60344

K7WPW5-1
type: Simple Sequence
modified: 2013-02-06
version: 1
mass: 42486
value: MTNLRKTHPLLKIANDALVDLPTPANISAWWNFGSLLGLCLGAQILTGLFLTMHYCSDITAAFSSVAHICRDVNYGWLIRNMHANGASFFFICIYMHIGRGLYYGSYLYKNTWNVGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYIGNSLVQWIWGGFSVDNATLTRFLAFHFLLPFVIVAMTMVHLIFLHETGSNNPTGLNSDADKISFHPYFSYKDLLGFTMLLLGLTSLALFLPNLLGDPDNFTPANPLMTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMIVPILHTSKQQSLTFRPLTQLLFWLLIADVIILTWIGGMPVEHPFVIIGQVASLLYFLIFLILMPAAGLMENKLINW

A0A0P0CW46
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 35
mnemonic: A0A0P0CW46_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP99F797808497C9B3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.9
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP5F4016E1455076F9
annotation: SIP5E32F2FDCF4DBEDE
annotation: SIPDFF3D3976566AC2A
annotation: SIP823AB5CC64329E17
annotation: SIPFD2E5C0BB84F2DCE
annotation: SIPCF66B484E0BE04BD
annotation: SIPB9973F37C4B5C830
annotation: SIP9CF53C558324C617
annotation: SIP70B4DBB5612496D0
annotation: SIP73483442369254AE
annotation: SIP182BD5C2B7269C7C
annotation: SIPDD84284E44624E12
annotation: SIP3C7A3EE923BE0C14
annotation: SIP3B3541BB4BBEFB15
annotation: SIPF1A401CCA79EDBE4
annotation: SIP99DBA6390B4A12B1
annotation: SIP8C3992400A2E169D
annotation: SIP390514B3BE1813D4
annotation: SIP3032C0F281316FF3
annotation: SIP8E47852496964E34
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/106
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/915
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0045277
classified with: GO_0004129
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0006119
sequence: A0A0P0CW46-1

A0A0P0CW46-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

cd01663
type: Resource
database: CDD
comment: Cyt_c_Oxidase_I
signature sequence match: CDD cd01663 match 1

IPR023615
type: Resource
database: InterPro
comment: Cyt_c_Oxase_su1_BS

IPR033944
type: Resource
database: InterPro
comment: Cyt_c_oxase_su1_dom

PS00077
type: Resource
database: PROSITE
comment: COX1_CUB
signature sequence match: PROSITE PS00077 match 1

SIP99F797808497C9B3
type: Structured Name
full name: Cytochrome c oxidase subunit 1
ec name: 7.1.1.9

COX1
type: Gene

SIP5F4016E1455076F9
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPB9973F37C4B5C830
type: Similarity Annotation
comment: Belongs to the heme-copper respiratory oxidase family.

SIP9CF53C558324C617
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt16tt37

-9218584761911404498tt16
type: Position
type: ExactPosition
position: 16
reference: A0A0P0CW46-1

-9218584761911404498tt37
type: Position
type: ExactPosition
position: 37
reference: A0A0P0CW46-1

SIP70B4DBB5612496D0
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt57tt83

-9218584761911404498tt57
type: Position
type: ExactPosition
position: 57
reference: A0A0P0CW46-1

-9218584761911404498tt83
type: Position
type: ExactPosition
position: 83
reference: A0A0P0CW46-1

SIP73483442369254AE
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt104tt128

-9218584761911404498tt104
type: Position
type: ExactPosition
position: 104
reference: A0A0P0CW46-1

-9218584761911404498tt128
type: Position
type: ExactPosition
position: 128
reference: A0A0P0CW46-1

SIP182BD5C2B7269C7C
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt148tt171

-9218584761911404498tt148
type: Position
type: ExactPosition
position: 148
reference: A0A0P0CW46-1

-9218584761911404498tt171
type: Position
type: ExactPosition
position: 171
reference: A0A0P0CW46-1

SIPDD84284E44624E12
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt183tt210

-9218584761911404498tt183
type: Position
type: ExactPosition
position: 183
reference: A0A0P0CW46-1

-9218584761911404498tt210
type: Position
type: ExactPosition
position: 210
reference: A0A0P0CW46-1

SIP3C7A3EE923BE0C14
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt243tt263

-9218584761911404498tt243
type: Position
type: ExactPosition
position: 243
reference: A0A0P0CW46-1

-9218584761911404498tt263
type: Position
type: ExactPosition
position: 263
reference: A0A0P0CW46-1

SIP3B3541BB4BBEFB15
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt270tt291

-9218584761911404498tt270
type: Position
type: ExactPosition
position: 270
reference: A0A0P0CW46-1

-9218584761911404498tt291
type: Position
type: ExactPosition
position: 291
reference: A0A0P0CW46-1

SIPF1A401CCA79EDBE4
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt303tt326

-9218584761911404498tt303
type: Position
type: ExactPosition
position: 303
reference: A0A0P0CW46-1

-9218584761911404498tt326
type: Position
type: ExactPosition
position: 326
reference: A0A0P0CW46-1

SIP99DBA6390B4A12B1
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt338tt359

-9218584761911404498tt338
type: Position
type: ExactPosition
position: 338
reference: A0A0P0CW46-1

-9218584761911404498tt359
type: Position
type: ExactPosition
position: 359
reference: A0A0P0CW46-1

SIP8C3992400A2E169D
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt379tt400

-9218584761911404498tt379
type: Position
type: ExactPosition
position: 379
reference: A0A0P0CW46-1

-9218584761911404498tt400
type: Position
type: ExactPosition
position: 400
reference: A0A0P0CW46-1

SIP390514B3BE1813D4
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt412tt436

-9218584761911404498tt412
type: Position
type: ExactPosition
position: 412
reference: A0A0P0CW46-1

-9218584761911404498tt436
type: Position
type: ExactPosition
position: 436
reference: A0A0P0CW46-1

SIP3032C0F281316FF3
type: Transmembrane Annotation
comment: Helical
range: -9218584761911404498tt456tt476

-9218584761911404498tt456
type: Position
type: ExactPosition
position: 456
reference: A0A0P0CW46-1

-9218584761911404498tt476
type: Position
type: ExactPosition
position: 476
reference: A0A0P0CW46-1

SIP8E47852496964E34
type: Domain Extent Annotation
comment: COX1
range: -9218584761911404498tt1tt516

-9218584761911404498tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0P0CW46-1

-9218584761911404498tt516
type: Position
type: ExactPosition
position: 516
reference: A0A0P0CW46-1

A0A0P0CW46-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 56952
value: MMITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGSLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVAYYAGKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGAIKWETPLLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIIAAFVHWFPLFSGYTLHSTWTKIHFGIMFLGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNTVSSFGSLISLIAVIMFLFIIWEAFSAKREVLSVEFTATNLEWLHGCPPPYHTFEEPAFVQVPQA

A0A1P8CYA3
type: Protein
reviewed: false
created: 2017-04-12
modified: 2022-12-14
version: 23
mnemonic: A0A1P8CYA3_9TELE
citation: SIP22A50FA279CE1A88
recommended name: SIP99F797808497C9B3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.9
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP679BA4CEE708D487
annotation: SIP320A8C4A18DB000D
annotation: SIP82FFD30447F072E4
annotation: SIP76E487745FE559DD
annotation: SIP8F63876184F0F205
annotation: SIP733109CB82329B04
annotation: SIP93D7E4EDCB5E2D9B
annotation: SIPE26837BE239F773A
annotation: SIP2B0C390F674CC98E
annotation: SIP22AFEB9DC7BA9722
annotation: SIP1E8DDB5B97717027
annotation: SIP914E5EC362F8ABE7
annotation: SIP1710C9AE1461401D
annotation: SIP1B010CBCB877B2C3
annotation: SIPF8AE5703A29B16EF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/915
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0004129
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0006119
sequence: A0A1P8CYA3-1

SIP22A50FA279CE1A88
type: Submission Citation
title: DNA barcoding of ornamental freshwater fish from South Africa.
author: Van Der Walt K.-A.
author: Makinen T.
author: Weyl O.
author: Collins R.
author: Swartz E.
date: 2016-01
submitted to: EMBL/GenBank/DDBJ

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP99F797808497C9B3
type: Structured Name
full name: Cytochrome c oxidase subunit 1
ec name: 7.1.1.9

COI
type: Gene

SIP679BA4CEE708D487
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIP93D7E4EDCB5E2D9B
type: Similarity Annotation
comment: Belongs to the heme-copper respiratory oxidase family.

SIPE26837BE239F773A
type: Transmembrane Annotation
comment: Helical
range: -9218580329502847954tt6tt24

-9218580329502847954tt6
type: Position
type: ExactPosition
position: 6
reference: A0A1P8CYA3-1

-9218580329502847954tt24
type: Position
type: ExactPosition
position: 24
reference: A0A1P8CYA3-1

SIP2B0C390F674CC98E
type: Transmembrane Annotation
comment: Helical
range: -9218580329502847954tt36tt58

-9218580329502847954tt36
type: Position
type: ExactPosition
position: 36
reference: A0A1P8CYA3-1

-9218580329502847954tt58
type: Position
type: ExactPosition
position: 58
reference: A0A1P8CYA3-1

SIP22AFEB9DC7BA9722
type: Transmembrane Annotation
comment: Helical
range: -9218580329502847954tt92tt112

-9218580329502847954tt92
type: Position
type: ExactPosition
position: 92
reference: A0A1P8CYA3-1

-9218580329502847954tt112
type: Position
type: ExactPosition
position: 112
reference: A0A1P8CYA3-1

SIP1E8DDB5B97717027
type: Transmembrane Annotation
comment: Helical
range: -9218580329502847954tt132tt154

-9218580329502847954tt132
type: Position
type: ExactPosition
position: 132
reference: A0A1P8CYA3-1

-9218580329502847954tt154
type: Position
type: ExactPosition
position: 154
reference: A0A1P8CYA3-1

SIP914E5EC362F8ABE7
type: Transmembrane Annotation
comment: Helical
range: -9218580329502847954tt166tt193

-9218580329502847954tt166
type: Position
type: ExactPosition
position: 166
reference: A0A1P8CYA3-1

-9218580329502847954tt193
type: Position
type: ExactPosition
position: 193
reference: A0A1P8CYA3-1

SIP1710C9AE1461401D
type: Domain Extent Annotation
comment: COX1
range: -9218580329502847954tt1tt217

-9218580329502847954tt1
type: Position
type: ExactPosition
position: 1
reference: A0A1P8CYA3-1

-9218580329502847954tt217
type: Position
type: ExactPosition
position: 217
reference: A0A1P8CYA3-1

A0A1P8CYA3-1
type: Simple Sequence
modified: 2017-04-12
version: 1
fragment: single
mass: 23105
value: LYLVFGAWAGMVGTALSLLIRAELSQPGSLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTIINMKPPAISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHL

A0A0P0CIG3
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 26
mnemonic: A0A0P0CIG3_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP43EA97D6E21C37A3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP92A098ACD5BF2E77
annotation: SIP19AA1F425325811E
annotation: SIP9BEB3A8AA99F9564
annotation: SIP4B14BB77E04231F4
annotation: SIP63F190C892CBB0C6
annotation: SIP64ECE0376E35559C
annotation: SIPC9377447E372B721
annotation: SIPCCDC50DFBFCD5B29
annotation: SIPA794F8228F886C0A
annotation: SIP500F9CDCB5FE6FA3
annotation: SIP6BA0DA5D44B07EE9
annotation: SIP2C759E41378A4FF7
annotation: SIP4F653B3BB93B50F3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0006120
sequence: A0A0P0CIG3-1

A0A0P0CIG3-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR010933
type: Resource
database: InterPro
comment: NADH_DH_su2_C

IPR003917
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_chain2

IPR001750
type: Resource
database: InterPro
comment: ND/Mrp_mem

PF06444
type: Resource
database: Pfam
comment: NADH_dehy_S2_C
signature sequence match: Pfam PF06444 match 1

PF00361
type: Resource
database: Pfam
comment: Proton_antipo_M
signature sequence match: Pfam PF00361 match 1

PR01436
type: Resource
database: PRINTS
comment: NADHDHGNASE2

SIP43EA97D6E21C37A3
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 2
ec name: 7.1.1.2

ND2
type: Gene

SIP92A098ACD5BF2E77
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIP4B14BB77E04231F4
type: Similarity Annotation
comment: Belongs to the complex I subunit 2 family.

SIP63F190C892CBB0C6
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt60tt80

-9218584761925776338tt60
type: Position
type: ExactPosition
position: 60
reference: A0A0P0CIG3-1

-9218584761925776338tt80
type: Position
type: ExactPosition
position: 80
reference: A0A0P0CIG3-1

SIP64ECE0376E35559C
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt92tt115

-9218584761925776338tt92
type: Position
type: ExactPosition
position: 92
reference: A0A0P0CIG3-1

-9218584761925776338tt115
type: Position
type: ExactPosition
position: 115
reference: A0A0P0CIG3-1

SIPC9377447E372B721
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt151tt170

-9218584761925776338tt151
type: Position
type: ExactPosition
position: 151
reference: A0A0P0CIG3-1

-9218584761925776338tt170
type: Position
type: ExactPosition
position: 170
reference: A0A0P0CIG3-1

SIPCCDC50DFBFCD5B29
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt177tt195

-9218584761925776338tt177
type: Position
type: ExactPosition
position: 177
reference: A0A0P0CIG3-1

-9218584761925776338tt195
type: Position
type: ExactPosition
position: 195
reference: A0A0P0CIG3-1

SIPA794F8228F886C0A
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt201tt218

-9218584761925776338tt201
type: Position
type: ExactPosition
position: 201
reference: A0A0P0CIG3-1

-9218584761925776338tt218
type: Position
type: ExactPosition
position: 218
reference: A0A0P0CIG3-1

SIP500F9CDCB5FE6FA3
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt239tt259

-9218584761925776338tt239
type: Position
type: ExactPosition
position: 239
reference: A0A0P0CIG3-1

-9218584761925776338tt259
type: Position
type: ExactPosition
position: 259
reference: A0A0P0CIG3-1

SIP6BA0DA5D44B07EE9
type: Transmembrane Annotation
comment: Helical
range: -9218584761925776338tt274tt293

-9218584761925776338tt274
type: Position
type: ExactPosition
position: 274
reference: A0A0P0CIG3-1

-9218584761925776338tt293
type: Position
type: ExactPosition
position: 293
reference: A0A0P0CIG3-1

SIP2C759E41378A4FF7
type: Domain Extent Annotation
comment: Proton_antipo_M
range: -9218584761925776338tt23tt286

-9218584761925776338tt23
type: Position
type: ExactPosition
position: 23
reference: A0A0P0CIG3-1

-9218584761925776338tt286
type: Position
type: ExactPosition
position: 286
reference: A0A0P0CIG3-1

SIP4F653B3BB93B50F3
type: Domain Extent Annotation
comment: NADH_dehy_S2_C
range: -9218584761925776338tt289tt342

-9218584761925776338tt289
type: Position
type: ExactPosition
position: 289
reference: A0A0P0CIG3-1

-9218584761925776338tt342
type: Position
type: ExactPosition
position: 342
reference: A0A0P0CIG3-1

A0A0P0CIG3-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 37946
value: MNPYILMTLAFGLGLGTLITLTSSHWLLAWMGLEMNTLAIIPLLAQHHHPRATEATTKYFLTQATAAAMLLFASTTNAWLSGQWEIQQMTHPIPTTIITLALALKIGLAPLHAWLPEVLQGLDLTAGLILSTWQKIAPFALLLQINVPTPLLLISLSLLSILVGGWGGLNQNQLRKILAYSSIAHLGWMVLVLQFSPSMTLLTLSLYIIMTSSLFLSFKTNKTTTINALATSWAKTPTLTLLIPPILLSLGGLPPLTGFMPKWLILQELTKQDLALAATVAALSALLSLYFYLRLCYAMTLTMSPNTIINTMPWRLPSTQPSLPLSITASLTICLLPLTPSILTMTTL

A0A0N7HXE4
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 24
mnemonic: A0A0N7HXE4_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIPC3FAAD39E4A0A720
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP58654AE636C3A910
annotation: SIPF36BAED1C95AAE39
annotation: SIP20D6471CDFC9FAE8
annotation: SIPE4223ED841507EAB
annotation: SIPC812829EE9911633
annotation: SIPDF50AFDF47E9987E
annotation: SIP6FCDF2C1CE944E89
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0042773
sequence: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

A0A0N7HXE4-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR001133
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_chain4L/K

IPR039428
type: Resource
database: InterPro
comment: NUOK/Mnh_C1-like

PTHR11434
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L
signature sequence match: PANTHER PTHR11434 match 1

PF00420
type: Resource
database: Pfam
comment: Oxidored_q2
signature sequence match: Pfam PF00420 match 1

SIPC3FAAD39E4A0A720
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 4L
ec name: 7.1.1.2

ND4L
type: Gene

SIP58654AE636C3A910
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

SIPE4223ED841507EAB
type: Similarity Annotation
comment: Belongs to the complex I subunit 4L family.

SIPC812829EE9911633
type: Transmembrane Annotation
comment: Helical
range: -9218584868948717522tt6tt22

-9218584868948717522tt6
type: Position
type: ExactPosition
position: 6
reference: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

-9218584868948717522tt22
type: Position
type: ExactPosition
position: 22
reference: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

SIPDF50AFDF47E9987E
type: Transmembrane Annotation
comment: Helical
range: -9218584868948717522tt29tt49

-9218584868948717522tt29
type: Position
type: ExactPosition
position: 29
reference: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

-9218584868948717522tt49
type: Position
type: ExactPosition
position: 49
reference: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

SIP6FCDF2C1CE944E89
type: Transmembrane Annotation
comment: Helical
range: -9218584868948717522tt61tt80

-9218584868948717522tt61
type: Position
type: ExactPosition
position: 61
reference: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

-9218584868948717522tt80
type: Position
type: ExactPosition
position: 80
reference: MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC

MSPIHFTFSATFILGLAGLAFHRSHLLSALLCLESMMLSLFLALSLWTLQLNSTSFSTSPLLLLAFSACEASVGLALLVATTRTHGTDRLQNLNLLQC
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 10597

A0A0P0D4G4
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 22
mnemonic: A0A0P0D4G4_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP35FCC5F74834FC6E
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP1DC79765B6C33321
annotation: SIP668A1EA057263618
annotation: SIP79009E5A1F7A61C0
annotation: SIP48366454A809FEB1
annotation: SIP87F4D61C17E80121
annotation: SIP53531A7E695FBBDC
annotation: SIP87579317DCA74D5D
annotation: SIP6F861DDB99D5D928
annotation: SIP7CC04C4B4CD6A27B
annotation: SIPFC4AC12F42AFF77D
annotation: SIP45A65A3A037F7C3A
annotation: SIPEB680988F95DA66C
annotation: SIP74FCC00281E23E83
annotation: SIP29D8AF286E8DC6AB
annotation: SIP8856EE8972D0D6D8
annotation: SIPEC68F916E02C51AA
annotation: SIPEC6986DD8D3F814D
annotation: SIPE5103F039FCB02DF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0031966
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0042773
sequence: A0A0P0D4G4-1

A0A0P0D4G4-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR000260
type: Resource
database: InterPro
comment: NADH4_N

IPR010227
type: Resource
database: InterPro
comment: NADH_Q_OxRdtase_chainM/4

IPR003918
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase

PTHR43507
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4
signature sequence match: PANTHER PTHR43507 match 1

PF01059
type: Resource
database: Pfam
comment: Oxidored_q5_N
signature sequence match: Pfam PF01059 match 1

PR01437
type: Resource
database: PRINTS
comment: NUOXDRDTASE4

TIGR01972
type: Resource
database: TIGRFAMs
comment: NDH_I_M
signature sequence match: TIGRFAMs TIGR01972 match 1

SIP35FCC5F74834FC6E
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 4
ec name: 7.1.1.2

ND4
type: Gene

SIP1DC79765B6C33321
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIP48366454A809FEB1
type: Similarity Annotation
comment: Belongs to the complex I subunit 4 family.

SIP87F4D61C17E80121
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt21tt42

-9218584761880686546tt21
type: Position
type: ExactPosition
position: 21
reference: A0A0P0D4G4-1

-9218584761880686546tt42
type: Position
type: ExactPosition
position: 42
reference: A0A0P0D4G4-1

SIP53531A7E695FBBDC
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt62tt81

-9218584761880686546tt62
type: Position
type: ExactPosition
position: 62
reference: A0A0P0D4G4-1

-9218584761880686546tt81
type: Position
type: ExactPosition
position: 81
reference: A0A0P0D4G4-1

SIP87579317DCA74D5D
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt93tt111

-9218584761880686546tt93
type: Position
type: ExactPosition
position: 93
reference: A0A0P0D4G4-1

-9218584761880686546tt111
type: Position
type: ExactPosition
position: 111
reference: A0A0P0D4G4-1

SIP6F861DDB99D5D928
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt117tt137

-9218584761880686546tt117
type: Position
type: ExactPosition
position: 117
reference: A0A0P0D4G4-1

-9218584761880686546tt137
type: Position
type: ExactPosition
position: 137
reference: A0A0P0D4G4-1

SIP7CC04C4B4CD6A27B
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt149tt168

-9218584761880686546tt149
type: Position
type: ExactPosition
position: 149
reference: A0A0P0D4G4-1

-9218584761880686546tt168
type: Position
type: ExactPosition
position: 168
reference: A0A0P0D4G4-1

SIPFC4AC12F42AFF77D
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt195tt217

-9218584761880686546tt195
type: Position
type: ExactPosition
position: 195
reference: A0A0P0D4G4-1

-9218584761880686546tt217
type: Position
type: ExactPosition
position: 217
reference: A0A0P0D4G4-1

SIP45A65A3A037F7C3A
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt229tt248

-9218584761880686546tt229
type: Position
type: ExactPosition
position: 229
reference: A0A0P0D4G4-1

-9218584761880686546tt248
type: Position
type: ExactPosition
position: 248
reference: A0A0P0D4G4-1

SIPEB680988F95DA66C
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt260tt279

-9218584761880686546tt260
type: Position
type: ExactPosition
position: 260
reference: A0A0P0D4G4-1

-9218584761880686546tt279
type: Position
type: ExactPosition
position: 279
reference: A0A0P0D4G4-1

SIP74FCC00281E23E83
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt286tt304

-9218584761880686546tt286
type: Position
type: ExactPosition
position: 286
reference: A0A0P0D4G4-1

-9218584761880686546tt304
type: Position
type: ExactPosition
position: 304
reference: A0A0P0D4G4-1

SIP29D8AF286E8DC6AB
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt310tt331

-9218584761880686546tt310
type: Position
type: ExactPosition
position: 310
reference: A0A0P0D4G4-1

-9218584761880686546tt331
type: Position
type: ExactPosition
position: 331
reference: A0A0P0D4G4-1

SIP8856EE8972D0D6D8
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt352tt372

-9218584761880686546tt352
type: Position
type: ExactPosition
position: 352
reference: A0A0P0D4G4-1

-9218584761880686546tt372
type: Position
type: ExactPosition
position: 372
reference: A0A0P0D4G4-1

SIPEC68F916E02C51AA
type: Transmembrane Annotation
comment: Helical
range: -9218584761880686546tt392tt415

-9218584761880686546tt392
type: Position
type: ExactPosition
position: 392
reference: A0A0P0D4G4-1

-9218584761880686546tt415
type: Position
type: ExactPosition
position: 415
reference: A0A0P0D4G4-1

SIPEC6986DD8D3F814D
type: Domain Extent Annotation
comment: Oxidored_q5_N
range: -9218584761880686546tt1tt110

-9218584761880686546tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0P0D4G4-1

-9218584761880686546tt110
type: Position
type: ExactPosition
position: 110
reference: A0A0P0D4G4-1

SIPE5103F039FCB02DF
type: Domain Extent Annotation
comment: Proton_antipo_M
range: -9218584761880686546tt113tt404

-9218584761880686546tt113
type: Position
type: ExactPosition
position: 113
reference: A0A0P0D4G4-1

-9218584761880686546tt404
type: Position
type: ExactPosition
position: 404
reference: A0A0P0D4G4-1

A0A0P0D4G4-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 51388
value: MLKILVPTIMLLPMAWTIPFHQLWPTALLYSLTIAFMSLTWLKTTTEAGWAFLSPYMATDPLSTPLLVLTCWLLPLMILASQNHMSAEPQNRQRTYISLLTSLQIFLIMAFGATEMIMFYLMFEATLIPTLIIITRWGNQAERLNAGTYFLFYTLAGSLPLLIALLLLQNSAGTLSLLTLQYKTPMQLFTYADKLWWTSCLLAFLVKTPLYGIHLWLPKAHVEAPIAGSMILAAVLLKLGGYGMIRIMSLLEPLSKELCYPFLIFALWGVIMTASTCLRQPDLKSLIAYSSVSHMGLVTAGILIQTPWGLTGALILMIAHGLTSSALFCLANTNYERTHSRTMILARGLQTAIPLMTTWWFIASLANLGLPPLPNLMGELMIITALFNWSKWTLLFTGAGTLITASYSLYMFLVTQQGPLPPHIIALDPTHSREHLLMALHLIPLLLLITKPELLWGWTA

A0A0P0C9L4
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 22
mnemonic: A0A0P0C9L4_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP0691DD681D8B27AA
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP4F9A7CD346488323
annotation: SIP39A711F7D203CECD
annotation: SIP39341109ED091BD8
annotation: SIP167046EBE177D1AC
annotation: SIP27A4E7D1E04FBDEA
annotation: SIP9B94F3207FB7EA45
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0031966
classified with: GO_0070469
classified with: GO_0008137
sequence: MNLATTLLLTSATLSAILAIVSFWLPLMAPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLLSPLMAFTWTATVLLLLTLGLIYEWVQGGLEWAE

A0A0P0C9L4-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR000440
type: Resource
database: InterPro
comment: NADH_UbQ/plastoQ_OxRdtase_su3

IPR038430
type: Resource
database: InterPro
comment: NDAH_ubi_oxred_su3_sf

PTHR11058
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3
signature sequence match: PANTHER PTHR11058 match 1

PF00507
type: Resource
database: Pfam
comment: Oxidored_q4
signature sequence match: Pfam PF00507 match 1

SIP0691DD681D8B27AA
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 3
ec name: 7.1.1.2

ND3
type: Gene

SIP4F9A7CD346488323
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.

SIP167046EBE177D1AC
type: Similarity Annotation
comment: Belongs to the complex I subunit 3 family.

SIP27A4E7D1E04FBDEA
type: Transmembrane Annotation
comment: Helical
range: -9218584761942470610tt52tt74

-9218584761942470610tt52
type: Position
type: ExactPosition
position: 52
reference: MNLATTLLLTSATLSAILAIVSFWLPLMAPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLLSPLMAFTWTATVLLLLTLGLIYEWVQGGLEWAE

-9218584761942470610tt74
type: Position
type: ExactPosition
position: 74
reference: MNLATTLLLTSATLSAILAIVSFWLPLMAPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLLSPLMAFTWTATVLLLLTLGLIYEWVQGGLEWAE

SIP9B94F3207FB7EA45
type: Transmembrane Annotation
comment: Helical
range: -9218584761942470610tt86tt108

-9218584761942470610tt86
type: Position
type: ExactPosition
position: 86
reference: MNLATTLLLTSATLSAILAIVSFWLPLMAPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLLSPLMAFTWTATVLLLLTLGLIYEWVQGGLEWAE

-9218584761942470610tt108
type: Position
type: ExactPosition
position: 108
reference: MNLATTLLLTSATLSAILAIVSFWLPLMAPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLLSPLMAFTWTATVLLLLTLGLIYEWVQGGLEWAE

MNLATTLLLTSATLSAILAIVSFWLPLMAPDYEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLLSPLMAFTWTATVLLLLTLGLIYEWVQGGLEWAE
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 12962

K7WRE5
type: Protein
reviewed: false
created: 2013-02-06
modified: 2022-12-14
version: 25
mnemonic: K7WRE5_9TELE
citation: http://purl.uniprot.org/citations/23313459
recommended name: SIP01806B802B154B42
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP404B87DBCB8FE34F
annotation: SIP3073BD8FED1F3A25
annotation: SIP1DA896D0D0627E45
annotation: SIP448498FC0D2FC97D
annotation: SIPDC21A9F8A06714CB
annotation: SIP8A7426516F3A1BFD
annotation: SIPB9C746F8DCFDCF17
annotation: SIP49D2BFC05B5F6DB3
annotation: SIP9DB182F77F9E9775
annotation: SIP84994A3361CC051D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0045263
classified with: GO_0015078
classified with: GO_0015986
sequence: K7WRE5-1

K7WRE5-citation-23313459
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

Mboes.exGL.1
type: Strain

IPR000568
type: Resource
database: InterPro
comment: ATP_synth_F0_asu

IPR023011
type: Resource
database: InterPro
comment: ATP_synth_F0_asu_AS

IPR045083
type: Resource
database: InterPro
comment: ATP_synth_F0_asu_bact/mt

IPR035908
type: Resource
database: InterPro
comment: F0_ATP_A_sf

PTHR11410
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT A
signature sequence match: PANTHER PTHR11410 match 1

PF00119
type: Resource
database: Pfam
comment: ATP-synt_A
signature sequence match: Pfam PF00119 match 1

PR00123
type: Resource
database: PRINTS
comment: ATPASEA

SSF81336
type: Resource
database: SUPFAM
comment: F1F0 ATP synthase subunit A
signature sequence match: SUPFAM SSF81336 match 1

TIGR01131
type: Resource
database: TIGRFAMs
comment: ATP_synt_6_or_A
signature sequence match: TIGRFAMs TIGR01131 match 1

PS00449
type: Resource
database: PROSITE
comment: ATPASE_A
signature sequence match: PROSITE PS00449 match 1

SIP01806B802B154B42
type: Structured Name
full name: ATP synthase subunit a

SIP404B87DBCB8FE34F
type: Function Annotation
comment: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.

SIP3073BD8FED1F3A25
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIP448498FC0D2FC97D
type: Similarity Annotation
comment: Belongs to the ATPase A chain family.

SIPDC21A9F8A06714CB
type: Transmembrane Annotation
comment: Helical
range: 21171471435248942tt12tt31

21171471435248942tt12
type: Position
type: ExactPosition
position: 12
reference: K7WRE5-1

21171471435248942tt31
type: Position
type: ExactPosition
position: 31
reference: K7WRE5-1

SIP8A7426516F3A1BFD
type: Transmembrane Annotation
comment: Helical
range: 21171471435248942tt68tt89

21171471435248942tt68
type: Position
type: ExactPosition
position: 68
reference: K7WRE5-1

21171471435248942tt89
type: Position
type: ExactPosition
position: 89
reference: K7WRE5-1

SIPB9C746F8DCFDCF17
type: Transmembrane Annotation
comment: Helical
range: 21171471435248942tt101tt118

21171471435248942tt101
type: Position
type: ExactPosition
position: 101
reference: K7WRE5-1

21171471435248942tt118
type: Position
type: ExactPosition
position: 118
reference: K7WRE5-1

SIP49D2BFC05B5F6DB3
type: Transmembrane Annotation
comment: Helical
range: 21171471435248942tt138tt159

21171471435248942tt138
type: Position
type: ExactPosition
position: 138
reference: K7WRE5-1

21171471435248942tt159
type: Position
type: ExactPosition
position: 159
reference: K7WRE5-1

SIP9DB182F77F9E9775
type: Transmembrane Annotation
comment: Helical
range: 21171471435248942tt171tt199

21171471435248942tt171
type: Position
type: ExactPosition
position: 171
reference: K7WRE5-1

21171471435248942tt199
type: Position
type: ExactPosition
position: 199
reference: K7WRE5-1

SIP84994A3361CC051D
type: Transmembrane Annotation
comment: Helical
range: 21171471435248942tt205tt223

21171471435248942tt205
type: Position
type: ExactPosition
position: 205
reference: K7WRE5-1

21171471435248942tt223
type: Position
type: ExactPosition
position: 223
reference: K7WRE5-1

K7WRE5-1
type: Simple Sequence
modified: 2013-02-06
version: 1
mass: 25182
value: MTLGLFDQFLSPVFLGVPLIALALGLPWILYPQPTSRWMNNRLLALQGCFISRFTQQIFQPLHPKGHMWAAMFTALMLFLVTLNTLGLLPYTFTPTTQLSLNMAFAVPLWLATVLIGMRYQPTHALGHLLPEGTPTPLIPLLIVIETASLFIRPLALGVRLTANLTAGHLLIQLTSTAVFTLMFLMPTLAFLTSILLLLLTLLEVAVAVIQAYVFVLLLSLYLQENL

K7WXZ2
type: Protein
reviewed: false
created: 2013-02-06
modified: 2022-12-14
version: 24
mnemonic: K7WXZ2_9TELE
citation: http://purl.uniprot.org/citations/23313459
recommended name: SIP1E250F07EB44E932
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP7AB9053799741712
annotation: SIPBD8F4C463C21CF89
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/812
classified with: GO_0000276
classified with: GO_0015078
classified with: GO_0015986
sequence: MPQLKLEPWFLILALAWFIFMTVAPRKVIEYSYPNRLSSKDNKAPKSLPWTWLWH

K7WXZ2-citation-23313459
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

Mboes.exGL.1
type: Strain

IPR001421
type: Resource
database: InterPro
comment: ATP8_metazoa

PF00895
type: Resource
database: Pfam
comment: ATP-synt_8
signature sequence match: Pfam PF00895 match 1

SIP1E250F07EB44E932
type: Structured Name
full name: ATP synthase protein 8

SIPBD8F4C463C21CF89
type: Similarity Annotation
comment: Belongs to the ATPase protein 8 family.

MPQLKLEPWFLILALAWFIFMTVAPRKVIEYSYPNRLSSKDNKAPKSLPWTWLWH
type: Simple Sequence
modified: 2013-02-06
version: 1
mass: 6660

A0A0P0D430
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 22
mnemonic: A0A0P0D430_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP63E3671E8FBB9F10
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP48128B4623945F63
annotation: SIP044A2E8CD3C322E8
annotation: SIPADCA0746E2BF10F9
annotation: SIPC018D574579C492B
annotation: SIP1785FDCB20D4AD92
annotation: SIP5D795D630FC9D1E4
annotation: SIPF1000CC4D75D5881
annotation: SIPF32C7D7FCABB4625
annotation: SIPF5C0830B40F0BECE
annotation: SIP6E263C832371BEDD
annotation: SIP4FA15376B2DBCC6D
annotation: SIPEA23542943439BD4
annotation: SIP1FB770A48F7B9CD7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0016020
classified with: GO_0005739
classified with: GO_0004129
classified with: GO_0019646
sequence: A0A0P0D430-1

A0A0P0D430-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

cd01665
type: Resource
database: CDD
comment: Cyt_c_Oxidase_III
signature sequence match: CDD cd01665 match 1

IPR024791
type: Resource
database: InterPro
comment: Cyt_c/ubiquinol_Oxase_su3

IPR033945
type: Resource
database: InterPro
comment: Cyt_c_oxase_su3_dom

IPR000298
type: Resource
database: InterPro
comment: Cyt_c_oxidase-like_su3

IPR035973
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su3-like_sf

IPR013833
type: Resource
database: InterPro
comment: Cyt_c_oxidase_su3_a-hlx

PTHR11403
type: Resource
database: PANTHER
comment: CYTOCHROME C OXIDASE SUBUNIT III
signature sequence match: PANTHER PTHR11403 match 1

PF00510
type: Resource
database: Pfam
comment: COX3
signature sequence match: Pfam PF00510 match 1

SSF81452
type: Resource
database: SUPFAM
comment: Cytochrome c oxidase subunit III-like
signature sequence match: SUPFAM SSF81452 match 1

PS50253
type: Resource
database: PROSITE
comment: COX3
signature sequence match: PROSITE PS50253 match 1

SIP63E3671E8FBB9F10
type: Structured Name
full name: Cytochrome c oxidase subunit 3

COX3
type: Gene

SIP48128B4623945F63
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPADCA0746E2BF10F9
type: Subunit Annotation
comment: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).

SIP1785FDCB20D4AD92
type: Similarity Annotation
comment: Belongs to the cytochrome c oxidase subunit 3 family.

SIP5D795D630FC9D1E4
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt16tt34

-9218584761881018322tt16
type: Position
type: ExactPosition
position: 16
reference: A0A0P0D430-1

-9218584761881018322tt34
type: Position
type: ExactPosition
position: 34
reference: A0A0P0D430-1

SIPF1000CC4D75D5881
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt40tt58

-9218584761881018322tt40
type: Position
type: ExactPosition
position: 40
reference: A0A0P0D430-1

-9218584761881018322tt58
type: Position
type: ExactPosition
position: 58
reference: A0A0P0D430-1

SIPF32C7D7FCABB4625
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt79tt102

-9218584761881018322tt79
type: Position
type: ExactPosition
position: 79
reference: A0A0P0D430-1

-9218584761881018322tt102
type: Position
type: ExactPosition
position: 102
reference: A0A0P0D430-1

SIPF5C0830B40F0BECE
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt129tt147

-9218584761881018322tt129
type: Position
type: ExactPosition
position: 129
reference: A0A0P0D430-1

-9218584761881018322tt147
type: Position
type: ExactPosition
position: 147
reference: A0A0P0D430-1

SIP6E263C832371BEDD
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt159tt177

-9218584761881018322tt159
type: Position
type: ExactPosition
position: 159
reference: A0A0P0D430-1

-9218584761881018322tt177
type: Position
type: ExactPosition
position: 177
reference: A0A0P0D430-1

SIP4FA15376B2DBCC6D
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt197tt219

-9218584761881018322tt197
type: Position
type: ExactPosition
position: 197
reference: A0A0P0D430-1

-9218584761881018322tt219
type: Position
type: ExactPosition
position: 219
reference: A0A0P0D430-1

SIPEA23542943439BD4
type: Transmembrane Annotation
comment: Helical
range: -9218584761881018322tt240tt260

-9218584761881018322tt240
type: Position
type: ExactPosition
position: 240
reference: A0A0P0D430-1

-9218584761881018322tt260
type: Position
type: ExactPosition
position: 260
reference: A0A0P0D430-1

SIP1FB770A48F7B9CD7
type: Domain Extent Annotation
comment: COX3
range: -9218584761881018322tt4tt261

-9218584761881018322tt4
type: Position
type: ExactPosition
position: 4
reference: A0A0P0D430-1

-9218584761881018322tt261
type: Position
type: ExactPosition
position: 261
reference: A0A0P0D430-1

A0A0P0D430-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 29802
value: MAHQAHAYHMVDPSPWPLTGAVAALLMTSGLAIWMHFHSMTLMTLGLILLLLTMYQWWRDIVREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGACWPPTGIMTLNPFEVPLLNTAVLLASGVTVTWAHHSIMEGNRKQAIQSLTLTILLGFYFTFLQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAVCLCRQIQYHFTSQHHFGFEAAAWYWHFVDVVWLFLYISIYWWGS

K7WVD7
type: Protein
reviewed: false
created: 2013-02-06
modified: 2022-12-14
version: 41
mnemonic: K7WVD7_9TELE
citation: http://purl.uniprot.org/citations/23313459
recommended name: SIP43EA97D6E21C37A3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP277A21DF579EBBDC
annotation: SIPB74CDC1BF9B4EB65
annotation: SIP1A44A8CEB79170E5
annotation: SIPC9BE01CDC9C5DA2D
annotation: SIPCB6AAD5DF16513F1
annotation: SIP29EDEEEF4B7DBDB4
annotation: SIP9711A0F5A6FF2D8F
annotation: SIP42BB8207DB9818C5
annotation: SIPA56CBD29374DADF9
annotation: SIP5F7F5599EA9FA1BD
annotation: SIPA21FC59F57F2E3B9
annotation: SIPDD38F82A78B1736A
annotation: SIPBF8B42098E967444
annotation: SIP9F94C792C6918469
annotation: SIPD540790308DA0B7C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0008137
classified with: GO_0006120
sequence: K7WVD7-1

K7WVD7-citation-23313459
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

Mboes.exGL.1
type: Strain

SIP43EA97D6E21C37A3
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 2
ec name: 7.1.1.2

nd2
type: Gene

SIP277A21DF579EBBDC
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIPC9BE01CDC9C5DA2D
type: Similarity Annotation
comment: Belongs to the complex I subunit 2 family.

SIPCB6AAD5DF16513F1
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt60tt80

21171471502292782tt60
type: Position
type: ExactPosition
position: 60
reference: K7WVD7-1

21171471502292782tt80
type: Position
type: ExactPosition
position: 80
reference: K7WVD7-1

SIP29EDEEEF4B7DBDB4
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt92tt115

21171471502292782tt92
type: Position
type: ExactPosition
position: 92
reference: K7WVD7-1

21171471502292782tt115
type: Position
type: ExactPosition
position: 115
reference: K7WVD7-1

SIP9711A0F5A6FF2D8F
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt151tt170

21171471502292782tt151
type: Position
type: ExactPosition
position: 151
reference: K7WVD7-1

21171471502292782tt170
type: Position
type: ExactPosition
position: 170
reference: K7WVD7-1

SIP42BB8207DB9818C5
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt177tt195

21171471502292782tt177
type: Position
type: ExactPosition
position: 177
reference: K7WVD7-1

21171471502292782tt195
type: Position
type: ExactPosition
position: 195
reference: K7WVD7-1

SIPA56CBD29374DADF9
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt201tt218

21171471502292782tt201
type: Position
type: ExactPosition
position: 201
reference: K7WVD7-1

21171471502292782tt218
type: Position
type: ExactPosition
position: 218
reference: K7WVD7-1

SIP5F7F5599EA9FA1BD
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt238tt254

21171471502292782tt238
type: Position
type: ExactPosition
position: 238
reference: K7WVD7-1

21171471502292782tt254
type: Position
type: ExactPosition
position: 254
reference: K7WVD7-1

SIPA21FC59F57F2E3B9
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt274tt293

21171471502292782tt274
type: Position
type: ExactPosition
position: 274
reference: K7WVD7-1

21171471502292782tt293
type: Position
type: ExactPosition
position: 293
reference: K7WVD7-1

SIPDD38F82A78B1736A
type: Transmembrane Annotation
comment: Helical
range: 21171471502292782tt323tt345

21171471502292782tt323
type: Position
type: ExactPosition
position: 323
reference: K7WVD7-1

21171471502292782tt345
type: Position
type: ExactPosition
position: 345
reference: K7WVD7-1

SIPBF8B42098E967444
type: Domain Extent Annotation
comment: Proton_antipo_M
range: 21171471502292782tt23tt286

21171471502292782tt23
type: Position
type: ExactPosition
position: 23
reference: K7WVD7-1

21171471502292782tt286
type: Position
type: ExactPosition
position: 286
reference: K7WVD7-1

SIP9F94C792C6918469
type: Domain Extent Annotation
comment: NADH_dehy_S2_C
range: 21171471502292782tt289tt343

21171471502292782tt289
type: Position
type: ExactPosition
position: 289
reference: K7WVD7-1

21171471502292782tt343
type: Position
type: ExactPosition
position: 343
reference: K7WVD7-1

21171471502292782tt348
type: Position
type: ExactPosition
position: 348
reference: K7WVD7-1

K7WVD7-1
type: Simple Sequence
modified: 2013-02-06
version: 1
fragment: single
mass: 37864
value: MNPYILMTLAFGLGLGTLITLSSSHWLLAWMGLEMNTLAIIPLLAQHHHPRATEATTKYFLTQATAAAMLLFASTTNAWLSGQWEIQQMTHPLPTTIITLALALKIGLAPLHAWLPEVLQGLDLTAGLILSTWQKIAPFALLLQINAPAPLMLISLSLLSILVGGWGGLNQNQLRKILAYSSIAHLGWMILVLQFSPSLTFLTLSLYIIMTSALFLSFKTNKTTTINSLATSWAKTPALTLLIPPILLSLGGLPPLTGFMPKWLILQELTKQDLALAATMAALSALLSLYFYLRLSYAMTLTMSPNTITNTIPWRLPSNQLSLPLSITASLTICLLPLAPTIMALTAF

A0A0P0D225
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 17
mnemonic: A0A0P0D225_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP1E250F07EB44E932
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP679B3B4672DEB87A
annotation: SIPBB3CF8BBEA42039F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/812
classified with: GO_0000276
classified with: GO_0015078
classified with: GO_0015986
sequence: MPQLKLKPWFPILALAWLIFMALAPRKVIEYSYPNRLTPQSSKTPKSLPWTWLWH

A0A0P0D225-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP1E250F07EB44E932
type: Structured Name
full name: ATP synthase protein 8

ATP8
type: Gene

SIPBB3CF8BBEA42039F
type: Similarity Annotation
comment: Belongs to the ATPase protein 8 family.

MPQLKLKPWFPILALAWLIFMALAPRKVIEYSYPNRLTPQSSKTPKSLPWTWLWH
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 6592

A0A0P0C961
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 28
mnemonic: A0A0P0C961_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP9D7E862BB8D3C835
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIPB259EE950E9C8856
annotation: SIPD236BF7B6BF51DFA
annotation: SIP3C5D50713E1F883A
annotation: SIP101A138910EC48B1
annotation: SIP0768844CF0BBD25A
annotation: SIP00B6D9F4C65F063B
annotation: SIPC61369ADA4240D65
annotation: SIPAF68BDF06E8BD75D
annotation: SIP943F0A792C0B6EBC
annotation: SIPFDD03E8271041C4D
annotation: SIP0DBC572291DAC0FE
annotation: SIP558BF9DBD19185FA
annotation: SIP236DA31E983D458D
annotation: SIPF85B4C633D4B8B06
annotation: SIP9243F4B0F5C1D0CF
annotation: SIPF1FE1F8D3164C54B
annotation: SIPA7C5DFCF14A885D1
annotation: SIP81781922A6900FC1
annotation: SIPB9C97A1B1114F274
annotation: SIPA34A5255D92E4EE0
annotation: SIP1C1D5B5435DF0298
annotation: SIP0434CDB1CD5BBCE7
annotation: SIPD3669A926A24465A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0008137
classified with: GO_0042773
sequence: A0A0P0C961-1

A0A0P0C961-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR010934
type: Resource
database: InterPro
comment: NADH_DH_su5_C

IPR018393
type: Resource
database: InterPro
comment: NADHpl_OxRdtase_5_subgr

IPR003945
type: Resource
database: InterPro
comment: NU5C-like

IPR001516
type: Resource
database: InterPro
comment: Proton_antipo_N

PTHR42829
type: Resource
database: PANTHER
comment: NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5
signature sequence match: PANTHER PTHR42829 match 1

PF06455
type: Resource
database: Pfam
comment: NADH5_C
signature sequence match: Pfam PF06455 match 1

PF00662
type: Resource
database: Pfam
comment: Proton_antipo_N
signature sequence match: Pfam PF00662 match 1

TIGR01974
type: Resource
database: TIGRFAMs
comment: NDH_I_L
signature sequence match: TIGRFAMs TIGR01974 match 1

SIP9D7E862BB8D3C835
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 5
ec name: 7.1.1.2

ND5
type: Gene

SIPB259EE950E9C8856
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIP101A138910EC48B1
type: Similarity Annotation
comment: Belongs to the complex I subunit 5 family.

SIP0768844CF0BBD25A
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt6tt24

-9218584761942834130tt6
type: Position
type: ExactPosition
position: 6
reference: A0A0P0C961-1

-9218584761942834130tt24
type: Position
type: ExactPosition
position: 24
reference: A0A0P0C961-1

SIP00B6D9F4C65F063B
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt44tt61

-9218584761942834130tt44
type: Position
type: ExactPosition
position: 44
reference: A0A0P0C961-1

-9218584761942834130tt61
type: Position
type: ExactPosition
position: 61
reference: A0A0P0C961-1

SIPC61369ADA4240D65
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt81tt101

-9218584761942834130tt81
type: Position
type: ExactPosition
position: 81
reference: A0A0P0C961-1

-9218584761942834130tt101
type: Position
type: ExactPosition
position: 101
reference: A0A0P0C961-1

SIPAF68BDF06E8BD75D
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt122tt139

-9218584761942834130tt122
type: Position
type: ExactPosition
position: 122
reference: A0A0P0C961-1

-9218584761942834130tt139
type: Position
type: ExactPosition
position: 139
reference: A0A0P0C961-1

SIP943F0A792C0B6EBC
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt145tt165

-9218584761942834130tt145
type: Position
type: ExactPosition
position: 145
reference: A0A0P0C961-1

-9218584761942834130tt165
type: Position
type: ExactPosition
position: 165
reference: A0A0P0C961-1

SIPFDD03E8271041C4D
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt177tt195

-9218584761942834130tt177
type: Position
type: ExactPosition
position: 177
reference: A0A0P0C961-1

-9218584761942834130tt195
type: Position
type: ExactPosition
position: 195
reference: A0A0P0C961-1

SIP0DBC572291DAC0FE
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt215tt239

-9218584761942834130tt215
type: Position
type: ExactPosition
position: 215
reference: A0A0P0C961-1

-9218584761942834130tt239
type: Position
type: ExactPosition
position: 239
reference: A0A0P0C961-1

SIP558BF9DBD19185FA
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt251tt273

-9218584761942834130tt251
type: Position
type: ExactPosition
position: 251
reference: A0A0P0C961-1

-9218584761942834130tt273
type: Position
type: ExactPosition
position: 273
reference: A0A0P0C961-1

SIP236DA31E983D458D
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt279tt300

-9218584761942834130tt279
type: Position
type: ExactPosition
position: 279
reference: A0A0P0C961-1

-9218584761942834130tt300
type: Position
type: ExactPosition
position: 300
reference: A0A0P0C961-1

SIPF85B4C633D4B8B06
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt307tt325

-9218584761942834130tt307
type: Position
type: ExactPosition
position: 307
reference: A0A0P0C961-1

-9218584761942834130tt325
type: Position
type: ExactPosition
position: 325
reference: A0A0P0C961-1

SIP9243F4B0F5C1D0CF
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt331tt353

-9218584761942834130tt331
type: Position
type: ExactPosition
position: 331
reference: A0A0P0C961-1

-9218584761942834130tt353
type: Position
type: ExactPosition
position: 353
reference: A0A0P0C961-1

SIPF1FE1F8D3164C54B
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt374tt396

-9218584761942834130tt374
type: Position
type: ExactPosition
position: 374
reference: A0A0P0C961-1

-9218584761942834130tt396
type: Position
type: ExactPosition
position: 396
reference: A0A0P0C961-1

SIPA7C5DFCF14A885D1
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt408tt430

-9218584761942834130tt408
type: Position
type: ExactPosition
position: 408
reference: A0A0P0C961-1

-9218584761942834130tt430
type: Position
type: ExactPosition
position: 430
reference: A0A0P0C961-1

SIP81781922A6900FC1
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt463tt479

-9218584761942834130tt463
type: Position
type: ExactPosition
position: 463
reference: A0A0P0C961-1

-9218584761942834130tt479
type: Position
type: ExactPosition
position: 479
reference: A0A0P0C961-1

SIPB9C97A1B1114F274
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt491tt511

-9218584761942834130tt491
type: Position
type: ExactPosition
position: 491
reference: A0A0P0C961-1

-9218584761942834130tt511
type: Position
type: ExactPosition
position: 511
reference: A0A0P0C961-1

SIPA34A5255D92E4EE0
type: Transmembrane Annotation
comment: Helical
range: -9218584761942834130tt594tt611

-9218584761942834130tt594
type: Position
type: ExactPosition
position: 594
reference: A0A0P0C961-1

-9218584761942834130tt611
type: Position
type: ExactPosition
position: 611
reference: A0A0P0C961-1

SIP1C1D5B5435DF0298
type: Domain Extent Annotation
comment: Proton_antipo_N
range: -9218584761942834130tt73tt122

-9218584761942834130tt73
type: Position
type: ExactPosition
position: 73
reference: A0A0P0C961-1

SIP0434CDB1CD5BBCE7
type: Domain Extent Annotation
comment: Proton_antipo_M
range: -9218584761942834130tt139tt422

-9218584761942834130tt422
type: Position
type: ExactPosition
position: 422
reference: A0A0P0C961-1

SIPD3669A926A24465A
type: Domain Extent Annotation
comment: NADH5_C
range: -9218584761942834130tt428tt609

-9218584761942834130tt428
type: Position
type: ExactPosition
position: 428
reference: A0A0P0C961-1

-9218584761942834130tt609
type: Position
type: ExactPosition
position: 609
reference: A0A0P0C961-1

A0A0P0C961-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 66970
value: MYLTSLIMTTSLALIFLLLLYPVIMTFVPSPQNTNHSPIQAKTAVKLAFFVSLTPLFLFINEGAETITTTWSWANTLTFDINISLSLDLYAIIFVPVALYVTWSILEFASWYMHADPLVDRFLKYLLIFIIAMIVLVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAVIYNRIGDIGLILAMAWIATNLNSWEIQQIFITAKNFDMTLPLLGLILAAAGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLFPLMEGNSTASTTCLCLGALTTLFTATCALTQNDIKKIVAFSTSSQLGLMMVTIGLNQPQLAFLHICTHAFFKAMLFLCSGSIIHSLNDEQDIRKMGGMHTLTPFTSSCMTLGSLALTGTPFLAGFFSKDAIIEAMNTSYLNAWALVLTLLATSFTAVYSLRMIFFVSMGSPRFSPLSPINENNPAVINPIKRLAYGTIIAGLLITSNMLPIKTPVMTMPPVLKLAALAVSILGALTALELASLTTKQFKSAPNLTLHHFSNMLGFFPAITHRSLPKLTLLLGQSIASQTIDQAWLEKTGPKSLVDLNTPVISTTSNIQQGMVKTYLSLFFFTTILATLLLIY

K7XBD5
type: Protein
reviewed: false
created: 2013-02-06
modified: 2022-12-14
version: 21
mnemonic: K7XBD5_9TELE
citation: http://purl.uniprot.org/citations/23313459
submitted name: SIP0CEAA2E23DA2BAA9
organism: http://purl.uniprot.org/taxonomy/1250792
annotation: SIP8FD7DA3C46A97C28
annotation: SIP667BD0F4477CD553
existence: Predicted Existence
classified with: http://purl.uniprot.org/keywords/689
classified with: GO_0005840
sequence: MFSTSAKIVKPNGEKPDEFESGISQALL

K7XBD5-citation-23313459
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

Mboes.exGL.1
type: Strain

SIP0CEAA2E23DA2BAA9
type: Structured Name
full name: Ribosomal protein S7

S7
type: Gene

SIP8FD7DA3C46A97C28
type: Region Annotation
comment: Disordered
range: 21171475461715246tt1tt28

21171475461715246tt1
type: Position
type: ExactPosition
position: 1
reference: MFSTSAKIVKPNGEKPDEFESGISQALL

21171475461715246tt28
type: Position
type: ExactPosition
position: 28
reference: MFSTSAKIVKPNGEKPDEFESGISQALL

MFSTSAKIVKPNGEKPDEFESGISQALL
type: Simple Sequence
modified: 2013-02-06
version: 1
fragment: single
mass: 3024

K7WQN5
type: Protein
reviewed: false
created: 2013-02-06
modified: 2022-12-14
version: 28
mnemonic: K7WQN5_9TELE
citation: http://purl.uniprot.org/citations/23313459
recommended name: SIPD7C66A1752115876
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP08D4A1E7FC6D9832
annotation: SIP3151F92D28B52B71
annotation: SIP6DAC2FCBCCAC40B7
annotation: SIPA1968FCFBD8DAC2F
annotation: SIP74C5387BB2291EC2
annotation: SIP0CBB813394D49CF9
annotation: SIPB2467F664CB0E6A2
annotation: SIP67A2B5A5F322B2EA
annotation: SIP2B3A9A08B2DBD159
annotation: SIP87A905B1C1C81565
annotation: SIP69269D01412725E0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0008137
sequence: K7WQN5-1

K7WQN5-citation-23313459
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

Mboes.exGL.1
type: Strain

MF_01350
type: Resource
database: HAMAP
comment: NDH1_NuoH
signature sequence match: HAMAP MF 01350 match 1

IPR001694
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_su1/FPO

IPR018086
type: Resource
database: InterPro
comment: NADH_UbQ_OxRdtase_su1_CS

PTHR11432
type: Resource
database: PANTHER
comment: NADH DEHYDROGENASE SUBUNIT 1
signature sequence match: PANTHER PTHR11432 match 1

PF00146
type: Resource
database: Pfam
comment: NADHdh
signature sequence match: Pfam PF00146 match 1

PS00667
type: Resource
database: PROSITE
comment: COMPLEX1_ND1_1
signature sequence match: PROSITE PS00667 match 1

PS00668
type: Resource
database: PROSITE
comment: COMPLEX1_ND1_2
signature sequence match: PROSITE PS00668 match 1

SIPD7C66A1752115876
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 1
ec name: 7.1.1.2

nd1
type: Gene

SIP6DAC2FCBCCAC40B7
type: Similarity Annotation
comment: Belongs to the complex I subunit 1 family.

SIPA1968FCFBD8DAC2F
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt6tt29

21171471419061550tt6
type: Position
type: ExactPosition
position: 6
reference: K7WQN5-1

21171471419061550tt29
type: Position
type: ExactPosition
position: 29
reference: K7WQN5-1

SIP74C5387BB2291EC2
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt72tt93

21171471419061550tt72
type: Position
type: ExactPosition
position: 72
reference: K7WQN5-1

21171471419061550tt93
type: Position
type: ExactPosition
position: 93
reference: K7WQN5-1

SIP0CBB813394D49CF9
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt105tt129

21171471419061550tt105
type: Position
type: ExactPosition
position: 105
reference: K7WQN5-1

21171471419061550tt129
type: Position
type: ExactPosition
position: 129
reference: K7WQN5-1

SIPB2467F664CB0E6A2
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt150tt171

21171471419061550tt150
type: Position
type: ExactPosition
position: 150
reference: K7WQN5-1

21171471419061550tt171
type: Position
type: ExactPosition
position: 171
reference: K7WQN5-1

SIP67A2B5A5F322B2EA
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt177tt194

21171471419061550tt177
type: Position
type: ExactPosition
position: 177
reference: K7WQN5-1

21171471419061550tt194
type: Position
type: ExactPosition
position: 194
reference: K7WQN5-1

SIP2B3A9A08B2DBD159
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt237tt257

21171471419061550tt237
type: Position
type: ExactPosition
position: 237
reference: K7WQN5-1

21171471419061550tt257
type: Position
type: ExactPosition
position: 257
reference: K7WQN5-1

SIP87A905B1C1C81565
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt263tt279

21171471419061550tt263
type: Position
type: ExactPosition
position: 263
reference: K7WQN5-1

21171471419061550tt279
type: Position
type: ExactPosition
position: 279
reference: K7WQN5-1

SIP69269D01412725E0
type: Transmembrane Annotation
comment: Helical
range: 21171471419061550tt299tt320

21171471419061550tt299
type: Position
type: ExactPosition
position: 299
reference: K7WQN5-1

21171471419061550tt320
type: Position
type: ExactPosition
position: 320
reference: K7WQN5-1

K7WQN5-1
type: Simple Sequence
modified: 2013-02-06
version: 1
mass: 35595
value: MMTTLVLPIINSLILIVFILLAVALLTLVERKVLGYMQLRKGPNVVGPYGLLQPVADGLKLFMKEPVRPSTASSLMFLLAPILALTLALTLWAPMPLPSPMADMTLGVLFILAISSLTVYTILGSGWASNSKYALIGALRAVAQTISYEVSLGLILLSTIIFAGGFTLQTFNIAQEAIWLIVPAWPLAVMWYVSTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANILLMNTLSAILFLGTSIIYYAPEISTLLLMTKATLLSTMFLWVRASYPRFRYDQLMHLTWKNFLPLTLAMVIWHFALSLALAGLPPHL

A0A0N7HXE3
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 21
mnemonic: A0A0N7HXE3_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIPD7C66A1752115876
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP614B2419A62EF163
annotation: SIP7FAE2E7563295736
annotation: SIPB2AE7AA04DC1A2A7
annotation: SIP3FE4C523613F4802
annotation: SIPC5FE6E327DFB96C0
annotation: SIP6737984B2A432F4E
annotation: SIPD99B9760269D916C
annotation: SIPDDB5987E48DD2F02
annotation: SIPF8F58DB764B36427
annotation: SIP5B0EF7A192BCB7B2
annotation: SIP77657F71D59954BA
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0008137
sequence: A0A0N7HXE3-1

A0A0N7HXE3-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIPD7C66A1752115876
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 1
ec name: 7.1.1.2

ND1
type: Gene

SIPB2AE7AA04DC1A2A7
type: Similarity Annotation
comment: Belongs to the complex I subunit 1 family.

SIP3FE4C523613F4802
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt6tt29

-9218584868948718546tt6
type: Position
type: ExactPosition
position: 6
reference: A0A0N7HXE3-1

-9218584868948718546tt29
type: Position
type: ExactPosition
position: 29
reference: A0A0N7HXE3-1

SIPC5FE6E327DFB96C0
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt72tt93

-9218584868948718546tt72
type: Position
type: ExactPosition
position: 72
reference: A0A0N7HXE3-1

-9218584868948718546tt93
type: Position
type: ExactPosition
position: 93
reference: A0A0N7HXE3-1

SIP6737984B2A432F4E
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt105tt129

-9218584868948718546tt105
type: Position
type: ExactPosition
position: 105
reference: A0A0N7HXE3-1

-9218584868948718546tt129
type: Position
type: ExactPosition
position: 129
reference: A0A0N7HXE3-1

SIPD99B9760269D916C
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt150tt171

-9218584868948718546tt150
type: Position
type: ExactPosition
position: 150
reference: A0A0N7HXE3-1

-9218584868948718546tt171
type: Position
type: ExactPosition
position: 171
reference: A0A0N7HXE3-1

SIPDDB5987E48DD2F02
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt177tt194

-9218584868948718546tt177
type: Position
type: ExactPosition
position: 177
reference: A0A0N7HXE3-1

-9218584868948718546tt194
type: Position
type: ExactPosition
position: 194
reference: A0A0N7HXE3-1

SIPF8F58DB764B36427
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt237tt257

-9218584868948718546tt237
type: Position
type: ExactPosition
position: 237
reference: A0A0N7HXE3-1

-9218584868948718546tt257
type: Position
type: ExactPosition
position: 257
reference: A0A0N7HXE3-1

SIP5B0EF7A192BCB7B2
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt263tt279

-9218584868948718546tt263
type: Position
type: ExactPosition
position: 263
reference: A0A0N7HXE3-1

-9218584868948718546tt279
type: Position
type: ExactPosition
position: 279
reference: A0A0N7HXE3-1

SIP77657F71D59954BA
type: Transmembrane Annotation
comment: Helical
range: -9218584868948718546tt299tt320

-9218584868948718546tt299
type: Position
type: ExactPosition
position: 299
reference: A0A0N7HXE3-1

-9218584868948718546tt320
type: Position
type: ExactPosition
position: 320
reference: A0A0N7HXE3-1

A0A0N7HXE3-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 35659
value: MMMTLVLPIINSLVLIIFILLAVAILTLVERKVLGYMQLRKGPNVVGPYGLLQPVADGLKLFMKEPVRPSTASSLMFLLAPILALTLALTLWAPMPLPSPMADMTLGVLFILAISSLTVYTILGSGWASNSKYPLIGALRAVAQTISYEVSLGLILLSTIIFAGGFTLQTFNIAQETIWLIIPAWPLAIMWYISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANILLMNTLSAILFLGTSIIYYAPEVSTLLLMIKATLLSAVFLWVRASYPRFRYDQLMHLTWKNFLPLTLAMVIWHFALSLALAGLPPHL

A0A0P0CQ11
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 20
mnemonic: A0A0P0CQ11_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP7BF6D4C4FDB5C391
enzyme: http://purl.uniprot.org/enzyme/7.1.1.2
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP04250D6739830321
annotation: SIP05D1B13D283FBD9A
annotation: SIPF93E3928CD6522EB
annotation: SIP27C1394798BE8C3F
annotation: SIPC06EB1983866CC92
annotation: PRO_5012475278
annotation: SIP6B6D2664DAC8EF1A
annotation: SIP2A27027B56DCE60E
annotation: SIP7E02C86A96D2F6BB
annotation: SIP689F7AE6CDCB60A3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/732
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0031966
classified with: GO_0070469
classified with: GO_0008137
sequence: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

A0A0P0CQ11-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR001457
type: Resource
database: InterPro
comment: NADH_UbQ/plastoQ_OxRdtase_su6

PF00499
type: Resource
database: Pfam
comment: Oxidored_q3
signature sequence match: Pfam PF00499 match 1

SIP7BF6D4C4FDB5C391
type: Structured Name
full name: NADH-ubiquinone oxidoreductase chain 6
ec name: 7.1.1.2

ND6
type: Gene

SIP04250D6739830321
type: Function Annotation
comment: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

SIP27C1394798BE8C3F
type: Similarity Annotation
comment: Belongs to the complex I subunit 6 family.

-9218584761917750226tt1
type: Position
type: ExactPosition
position: 1
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

-9218584761917750226tt15
type: Position
type: ExactPosition
position: 15
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

PRO_5012475278
type: Chain Annotation
comment: NADH-ubiquinone oxidoreductase chain 6
mass: 16482
range: -9218584761917750226tt16tt173

-9218584761917750226tt16
type: Position
type: ExactPosition
position: 16
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

-9218584761917750226tt173
type: Position
type: ExactPosition
position: 173
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

SIP6B6D2664DAC8EF1A
type: Transmembrane Annotation
comment: Helical
range: -9218584761917750226tt27tt46

-9218584761917750226tt27
type: Position
type: ExactPosition
position: 27
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

-9218584761917750226tt46
type: Position
type: ExactPosition
position: 46
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

SIP2A27027B56DCE60E
type: Transmembrane Annotation
comment: Helical
range: -9218584761917750226tt53tt75

-9218584761917750226tt53
type: Position
type: ExactPosition
position: 53
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

-9218584761917750226tt75
type: Position
type: ExactPosition
position: 75
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

SIP7E02C86A96D2F6BB
type: Transmembrane Annotation
comment: Helical
range: -9218584761917750226tt87tt110

-9218584761917750226tt87
type: Position
type: ExactPosition
position: 87
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

-9218584761917750226tt110
type: Position
type: ExactPosition
position: 110
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

SIP689F7AE6CDCB60A3
type: Transmembrane Annotation
comment: Helical
range: -9218584761917750226tt131tt159

-9218584761917750226tt131
type: Position
type: ExactPosition
position: 131
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

-9218584761917750226tt159
type: Position
type: ExactPosition
position: 159
reference: MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV

MVFFMFSLLFGLVLGLAAVASNPSPYFAALGLVVVAGTGFGVLVGHGGSFLSLILFLIYLGGMLVVFAYSAALAAEPYPEGWGSWPVLGMMLVYLLGVGVVAGGFWGGWYEGSWVSADELSEVSVFRGDMGGIALMYLTGGKLLIMGAWVLLLTLFVVLELTRGLSRGTLRAV
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 18185

A0A1P8CY96
type: Protein
reviewed: false
created: 2017-04-12
modified: 2022-12-14
version: 23
mnemonic: A0A1P8CY96_9TELE
citation: SIP22A50FA279CE1A88
recommended name: SIP99F797808497C9B3
enzyme: http://purl.uniprot.org/enzyme/7.1.1.9
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIPF5EEE8FDA0A982EB
annotation: SIP444484A64D0565AC
annotation: SIPAD1DEE835470D612
annotation: SIPFEDC18FA2198587C
annotation: SIP4ED384164A5399BC
annotation: SIP41FFDF706B1028C8
annotation: SIPCEA4E30BD0463FEB
annotation: SIP9A721D73E8273CC0
annotation: SIP7928EAEE665C4C7F
annotation: SIPCCF2EDEB60CB1AA0
annotation: SIP2C6FF5B13B49C36C
annotation: SIPA939327568BD2EEC
annotation: SIPCF983F0102011167
annotation: SIPEC4F6330587154E0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/186
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/915
classified with: http://purl.uniprot.org/keywords/1278
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0070469
classified with: GO_0004129
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0006119
sequence: A0A1P8CY96-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP99F797808497C9B3
type: Structured Name
full name: Cytochrome c oxidase subunit 1
ec name: 7.1.1.9

COI
type: Gene

SIPF5EEE8FDA0A982EB
type: Function Annotation
comment: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

SIPCEA4E30BD0463FEB
type: Similarity Annotation
comment: Belongs to the heme-copper respiratory oxidase family.

SIP9A721D73E8273CC0
type: Transmembrane Annotation
comment: Helical
range: -9218580329502975954tt43tt63

-9218580329502975954tt43
type: Position
type: ExactPosition
position: 43
reference: A0A1P8CY96-1

-9218580329502975954tt63
type: Position
type: ExactPosition
position: 63
reference: A0A1P8CY96-1

SIP7928EAEE665C4C7F
type: Transmembrane Annotation
comment: Helical
range: -9218580329502975954tt84tt108

-9218580329502975954tt84
type: Position
type: ExactPosition
position: 84
reference: A0A1P8CY96-1

-9218580329502975954tt108
type: Position
type: ExactPosition
position: 108
reference: A0A1P8CY96-1

SIPCCF2EDEB60CB1AA0
type: Transmembrane Annotation
comment: Helical
range: -9218580329502975954tt128tt151

-9218580329502975954tt128
type: Position
type: ExactPosition
position: 128
reference: A0A1P8CY96-1

-9218580329502975954tt151
type: Position
type: ExactPosition
position: 151
reference: A0A1P8CY96-1

SIP2C6FF5B13B49C36C
type: Transmembrane Annotation
comment: Helical
range: -9218580329502975954tt163tt190

-9218580329502975954tt163
type: Position
type: ExactPosition
position: 163
reference: A0A1P8CY96-1

-9218580329502975954tt190
type: Position
type: ExactPosition
position: 190
reference: A0A1P8CY96-1

SIPA939327568BD2EEC
type: Domain Extent Annotation
comment: COX1
range: -9218580329502975954tt1tt214

-9218580329502975954tt1
type: Position
type: ExactPosition
position: 1
reference: A0A1P8CY96-1

-9218580329502975954tt214
type: Position
type: ExactPosition
position: 214
reference: A0A1P8CY96-1

A0A1P8CY96-1
type: Simple Sequence
modified: 2017-04-12
version: 1
fragment: single
mass: 22716
value: VFGAWAGMVGTALSLLIRAELSQPGSLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGISSILGAINFITTIINMKPPAISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHL

A0A0P0CIH8
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 24
mnemonic: A0A0P0CIH8_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP04BB22F94509478D
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP4A7E198DF669FC43
annotation: SIPEAA5D8FFE9FC8006
annotation: SIP78D3698F5805DF65
annotation: SIP11F6B89ED7ACE3CE
annotation: SIPD1DADF350F19ADCF
annotation: SIP4D8E34BC8193B2A7
annotation: SIP098A3FF9F6CC1B9A
annotation: SIP0EE7BB6776FEC581
annotation: SIPF9F33B564ACACCBD
annotation: SIP3E5D98BD332A313E
annotation: SIP8994FCD2794B6FE8
annotation: SIPE0BD27D6ED725EA6
annotation: SIPA5844F084ADB711F
annotation: SIP0BF0AF056BC8DAA9
annotation: SIP90AD5A961FB0C1C0
annotation: SIP58F4D9A202BB7FEB
annotation: SIPB138FB1DA191B652
annotation: SIPEAEF2E8C706DE9A8
annotation: SIP58112229D0F181EA
annotation: SIP8E60A879D7098EF5
annotation: SIP71F05CB24B78CFFF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/679
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/830
classified with: GO_0005743
classified with: GO_0045275
classified with: GO_0046872
classified with: GO_0008121
classified with: GO_0022904
sequence: A0A0P0CIH8-1

A0A0P0CIH8-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP04BB22F94509478D
type: Structured Name
full name: Cytochrome b

CYTB
type: Gene

SIP4A7E198DF669FC43
type: Function Annotation
comment: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

SIPEAA5D8FFE9FC8006
type: Cofactor Annotation
comment: Binds 2 heme groups non-covalently.
cofactor: CHEBI_60344

SIP78D3698F5805DF65
type: Cofactor Annotation
comment: Binds 2 heme groups non-covalently.
cofactor: CHEBI_30413

SIPD1DADF350F19ADCF
type: Similarity Annotation
comment: Belongs to the cytochrome b family.

SIP4D8E34BC8193B2A7
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt29tt51

-9218584761925754834tt29
type: Position
type: ExactPosition
position: 29
reference: A0A0P0CIH8-1

-9218584761925754834tt51
type: Position
type: ExactPosition
position: 51
reference: A0A0P0CIH8-1

SIP098A3FF9F6CC1B9A
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt87tt107

-9218584761925754834tt87
type: Position
type: ExactPosition
position: 87
reference: A0A0P0CIH8-1

-9218584761925754834tt107
type: Position
type: ExactPosition
position: 107
reference: A0A0P0CIH8-1

SIP0EE7BB6776FEC581
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt113tt133

-9218584761925754834tt113
type: Position
type: ExactPosition
position: 113
reference: A0A0P0CIH8-1

-9218584761925754834tt133
type: Position
type: ExactPosition
position: 133
reference: A0A0P0CIH8-1

SIPF9F33B564ACACCBD
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt145tt166

-9218584761925754834tt145
type: Position
type: ExactPosition
position: 145
reference: A0A0P0CIH8-1

-9218584761925754834tt166
type: Position
type: ExactPosition
position: 166
reference: A0A0P0CIH8-1

SIP3E5D98BD332A313E
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt178tt200

-9218584761925754834tt178
type: Position
type: ExactPosition
position: 178
reference: A0A0P0CIH8-1

-9218584761925754834tt200
type: Position
type: ExactPosition
position: 200
reference: A0A0P0CIH8-1

SIP8994FCD2794B6FE8
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt229tt250

-9218584761925754834tt229
type: Position
type: ExactPosition
position: 229
reference: A0A0P0CIH8-1

-9218584761925754834tt250
type: Position
type: ExactPosition
position: 250
reference: A0A0P0CIH8-1

SIPE0BD27D6ED725EA6
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt288tt308

-9218584761925754834tt288
type: Position
type: ExactPosition
position: 288
reference: A0A0P0CIH8-1

-9218584761925754834tt308
type: Position
type: ExactPosition
position: 308
reference: A0A0P0CIH8-1

SIPA5844F084ADB711F
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt320tt340

-9218584761925754834tt320
type: Position
type: ExactPosition
position: 320
reference: A0A0P0CIH8-1

-9218584761925754834tt340
type: Position
type: ExactPosition
position: 340
reference: A0A0P0CIH8-1

SIP0BF0AF056BC8DAA9
type: Transmembrane Annotation
comment: Helical
range: -9218584761925754834tt346tt366

-9218584761925754834tt346
type: Position
type: ExactPosition
position: 346
reference: A0A0P0CIH8-1

-9218584761925754834tt366
type: Position
type: ExactPosition
position: 366
reference: A0A0P0CIH8-1

SIP90AD5A961FB0C1C0
type: Domain Extent Annotation
comment: CYTB_NTER
range: -9218584761925754834tt1tt209

-9218584761925754834tt1
type: Position
type: ExactPosition
position: 1
reference: A0A0P0CIH8-1

-9218584761925754834tt209
type: Position
type: ExactPosition
position: 209
reference: A0A0P0CIH8-1

SIP58F4D9A202BB7FEB
type: Domain Extent Annotation
comment: CYTB_CTER
range: -9218584761925754834tt210tt379

-9218584761925754834tt210
type: Position
type: ExactPosition
position: 210
reference: A0A0P0CIH8-1

-9218584761925754834tt379
type: Position
type: ExactPosition
position: 379
reference: A0A0P0CIH8-1

SIPB138FB1DA191B652
type: Binding Site Annotation
comment: axial binding residue
ligand: b562
ligand part: SIP3DC6E50EC00A509E
range: -9218584761925754834tt83tt83

-9218584761925754834tt83
type: Position
type: ExactPosition
position: 83
reference: A0A0P0CIH8-1

SIPEAEF2E8C706DE9A8
type: Binding Site Annotation
comment: axial binding residue
ligand: b566
ligand part: SIPDEA17CD1404F7F17
range: -9218584761925754834tt97tt97

-9218584761925754834tt97
type: Position
type: ExactPosition
position: 97
reference: A0A0P0CIH8-1

SIP58112229D0F181EA
type: Binding Site Annotation
comment: axial binding residue
ligand: b562
ligand part: SIP3DC6E50EC00A509E
range: -9218584761925754834tt182tt182

-9218584761925754834tt182
type: Position
type: ExactPosition
position: 182
reference: A0A0P0CIH8-1

SIP8E60A879D7098EF5
type: Binding Site Annotation
comment: axial binding residue
ligand: b566
ligand part: SIPDEA17CD1404F7F17
range: -9218584761925754834tt196tt196

-9218584761925754834tt196
type: Position
type: ExactPosition
position: 196
reference: A0A0P0CIH8-1

-9218584761925754834tt201
type: Position
type: ExactPosition
position: 201
reference: A0A0P0CIH8-1

b562
subclass of: CHEBI_60344

b566
subclass of: CHEBI_60344

A0A0P0CIH8-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 42533
value: MTNLRKTHPLLKIANDALVDLPTPANISAWWNFGSLLGLCLGAQILTGLFLTMHYCSDITAAFSSVAHICRDVNYGWLIRNMHANGASFFFICIYMHIGRGLYYGSYLYKNTWNVGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYIGNSLVQWIWGGFSVDNATLTRFLAFHFLLPFVIVAMTMVHLIFLHETGSNNPTGLNSDADKISFHPYFSYKDLLGFTILLLGLTSLALFLPNLLGDPDNFTPANPLMTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMVVPILHTSKQQSLTFRPLAQLLFWLLIADVIILTWIGGMPVEHPFVIIGQAASVLYFMIFLILMPTASWMENKLINW

A0A0P0CYB8
type: Protein
reviewed: false
created: 2016-01-20
modified: 2022-12-14
version: 22
mnemonic: A0A0P0CYB8_9TELE
citation: http://purl.uniprot.org/citations/26472588
recommended name: SIP01806B802B154B42
organism: http://purl.uniprot.org/taxonomy/1250792
encoded in: Mitochondrion
annotation: SIP843FD14ED87588D4
annotation: SIPB43E59889611EB8A
annotation: SIP7C7C2205DF12FEF2
annotation: SIPBEC3E35970E11A6E
annotation: SIPE83179F896A7AB81
annotation: SIPAF35CB7FBF60E608
annotation: SIPEF10874E55558660
annotation: SIPD2F39FAB9EBC4032
annotation: SIPE82D6A9783F97A8B
annotation: SIP1D8EA3D81052E40F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0045263
classified with: GO_0015078
classified with: GO_0015986
sequence: A0A0P0CYB8-1

A0A0P0CYB8-citation-26472588
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

SIP01806B802B154B42
type: Structured Name
full name: ATP synthase subunit a

ATP6
type: Gene

SIP843FD14ED87588D4
type: Function Annotation
comment: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.

SIPB43E59889611EB8A
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIPBEC3E35970E11A6E
type: Similarity Annotation
comment: Belongs to the ATPase A chain family.

SIPE83179F896A7AB81
type: Transmembrane Annotation
comment: Helical
range: -9218584761909075922tt12tt31

-9218584761909075922tt12
type: Position
type: ExactPosition
position: 12
reference: A0A0P0CYB8-1

-9218584761909075922tt31
type: Position
type: ExactPosition
position: 31
reference: A0A0P0CYB8-1

SIPAF35CB7FBF60E608
type: Transmembrane Annotation
comment: Helical
range: -9218584761909075922tt69tt89

-9218584761909075922tt69
type: Position
type: ExactPosition
position: 69
reference: A0A0P0CYB8-1

-9218584761909075922tt89
type: Position
type: ExactPosition
position: 89
reference: A0A0P0CYB8-1

SIPEF10874E55558660
type: Transmembrane Annotation
comment: Helical
range: -9218584761909075922tt101tt118

-9218584761909075922tt101
type: Position
type: ExactPosition
position: 101
reference: A0A0P0CYB8-1

-9218584761909075922tt118
type: Position
type: ExactPosition
position: 118
reference: A0A0P0CYB8-1

SIPD2F39FAB9EBC4032
type: Transmembrane Annotation
comment: Helical
range: -9218584761909075922tt138tt159

-9218584761909075922tt138
type: Position
type: ExactPosition
position: 138
reference: A0A0P0CYB8-1

-9218584761909075922tt159
type: Position
type: ExactPosition
position: 159
reference: A0A0P0CYB8-1

SIPE82D6A9783F97A8B
type: Transmembrane Annotation
comment: Helical
range: -9218584761909075922tt171tt199

-9218584761909075922tt171
type: Position
type: ExactPosition
position: 171
reference: A0A0P0CYB8-1

-9218584761909075922tt199
type: Position
type: ExactPosition
position: 199
reference: A0A0P0CYB8-1

SIP1D8EA3D81052E40F
type: Transmembrane Annotation
comment: Helical
range: -9218584761909075922tt205tt223

-9218584761909075922tt205
type: Position
type: ExactPosition
position: 205
reference: A0A0P0CYB8-1

-9218584761909075922tt223
type: Position
type: ExactPosition
position: 223
reference: A0A0P0CYB8-1

A0A0P0CYB8-1
type: Simple Sequence
modified: 2016-01-20
version: 1
mass: 25107
value: MTLGLFDQFLSPVFLGVPLIALALSLPWILYPQPTSRWVNNRLLALQGCFINRFTQQIFQPISPKGHKWAALFTALMLFLVTLNTLGLLPYTFTPTTQLSLNMAFAVPLWLATVLIGMRHQPTHALGHLLPEGTPAPLIPLLIIIETASLFIRPLALGVRLTANLTAGHLLIQLTSTAVFTLMFLMPTLAFLTSILLLLLTLLEVAVALIQAYVFVLLLSLYLQENL