Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Major facilitator superfamily (MFS) profile
Phosphoribosylformylglycinamidine cyclo-ligase
Urease accessory protein UreH-like transmembrane
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Solute-binding protein family 3/N-terminal
Galactose-1-phosphate uridyl transferase N-terminal
4-hydroxy-tetrahydrodipicolinate synthase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Haem-binding uptake Tiki superfamily ChaN
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
AB hydrolase-1 domain-containing protein
tRNA N6-adenosine threonylcarbamoyltransferase
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Cytochrome b/b6 N-terminal region profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
RND efflux pump membrane fusion protein barrel-sandwich
UPF0173 metal-dependent hydrolase Geob_3274
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Contractile injection system tube protein N-terminal
Prokaryotic-type class I peptide chain release factors
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Outer membrane protein beta-barrel domain-containing protein
RNA binding; important for wobble base 34 recognition
Chromosomal replication initiator DnaA C-terminal
TIGR03016 family PEP-CTERM system-associated outer membrane protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Cytochrome b561 bacterial/Ni-hydrogenase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Bacterial type II secretion system protein E
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Dinitrogenase iron-molybdenum cofactor biosynthesis
Pyridoxamine 5'-phosphate oxidase putative
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Right handed beta helix domain-containing protein
Cytochrome C biogenesis protein transmembrane
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Inner membrane protein YgaP-like transmembrane
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Transposase IS116/IS110/IS902 C-terminal
DNA replication/recombination mediator RecO N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
UDP N-acetylglucosamine O-acyltransferase C-terminal
Sodium symporter small subunit predicted
Holliday junction branch migration complex subunit RuvA
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glutamate-1-semialdehyde 2,1-aminomutase
Pyrimidine/purine nucleoside phosphorylase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
DNA-directed RNA polymerase subunit beta
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
N-acetyl-gamma-glutamyl-phosphate reductase
Penicillin-binding protein transpeptidase
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Probable glycine dehydrogenase (decarboxylating) subunit 1
Phenylalanine--tRNA ligase alpha subunit
Glycoside hydrolase family 57 N-terminal
Tryptophan synthase beta chain-like PALP
Methylene-tetrahydrofolate reductase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
N6 adenine-specific DNA methyltransferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Resolvase/invertase-type recombinase catalytic
Pyruvate/ketoisovalerate oxidoreductase catalytic
Polysaccharide biosynthesis protein CapD-like
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Positions MEP for the nucleophilic attack
Interaction with polymerase core subunit RpoC
Translocation and assembly module subunit TamA
Holliday junction branch migration complex subunit RuvB
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
O-(5'-phospho-DNA)-tyrosine intermediate
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Mannose-6-phosphate isomerase type II C-terminal
ATP phosphoribosyltransferase regulatory subunit
S-adenosylmethionine-dependent methyltransferase
Large-conductance mechanosensitive channel
Glycosyltransferase subfamily 4-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Protein-PII uridylyltransferase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
DNA-directed RNA polymerase subunit beta'
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Polyribonucleotide nucleotidyltransferase
Acetylserotonin O-methyltransferase dimerisation
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Phosphoribosylformylglycinamidine synthase linker
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Organic solvent tolerance-like N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Reversibly protonated during proton transport
Type II secretion system protein GspE N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Ribosomal RNA small subunit methyltransferase H
Important for beta-aspartyl-AMP intermediate formation
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Saccharopine dehydrogenase-like C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Bifunctional purine biosynthesis protein PurH
Carbamoyl-phosphate synthase small subunit N-terminal
Plays an important role in substrate specificity
Peptidase S9 prolyl oligopeptidase catalytic
Pilus formation protein N-terminal domain-containing protein
Flagellar hook-length control protein-like C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Disulphide bond isomerase DsbC/G N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
Probable nicotinate-nucleotide adenylyltransferase
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit
Manganese/iron superoxide dismutase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
3-deoxy-manno-octulosonate cytidylyltransferase
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Glycoside hydrolase family 42 N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Prepilin type IV endopeptidase peptidase
DNA mismatch repair proteins mutS family
RNA polymerase sigma factor 70 region 4 type 2
nitrite reductase (cytochrome; ammonia-forming)
DNA-directed RNA polymerase RpoA/D/Rpb3-type
F420-non-reducing hydrogenase iron-sulfur subunit D
DNA-directed RNA polymerase subunit omega
Polysaccharide chain length determinant N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Exosortase system-associated protein, TIGR04073 family
Important for interaction with partner proteins
NADH:ubiquinone oxidoreductase 30kDa subunit
Translation elongation factor P/YeiP central
Lipocalin-like domain-containing protein
N-(5'-phosphoribosyl)anthranilate isomerase
UDP-3-O-acylglucosamine N-acyltransferase
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Involved in allosteric activation by GTP
Membrane fusion protein biotin-lipoyl like
Alpha-L-rhamnosidase six-hairpin glycosidase
Putative glycogen debranching enzyme N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Histidine-specific methyltransferase SAM-dependent
Flagellar motor switch protein FliN-like C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Cytochrome b/b6 C-terminal region profile
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Chromosomal replication initiator protein DnaA
Flagellar assembly protein T N-terminal domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycogen debranching enzyme bacterial and archaeal type N-terminal
DNA polymerase III delta subunit C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Phosphotransferase system enzyme I N-terminal
Type I restriction enzyme R protein N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Transcription antitermination protein NusB
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Essential for prephenate dehydratase activity
Probable transcriptional regulatory protein Geob_2326
Archaeal glycosylation protein B peripheral
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Alanyl-transfer RNA synthetases family profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Membrane iron-sulfur containing protein FtrD-like
Antitoxin Xre/MbcA/ParS-like toxin-binding
3-phosphoshikimate 1-carboxyvinyltransferase
Glycine cleavage T-protein C-terminal barrel
Important for substrate specificity; cannot use PPi as phosphoryl donor
tRNA (guanine-N(1)-)-methyltransferase C-terminal
MCP methyltransferase CheR-type SAM-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Type II secretion system protein GspC N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl-tRNA(Gln) amidotransferase subunit A
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Ribosomal RNA adenine methylase transferase N-terminal
Flagellar Assembly Protein A N-terminal region
Cation-transporting P-type ATPase N-terminal
Formylmethanofuran dehydrogenase subunit E
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Glycine zipper 2TM domain-containing protein
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Type II secretion system protein GspG C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
UDP-N-acetylmuramoylalanine--D-glutamate ligase
ATP-dependent Clp protease ATP-binding subunit ClpX
UDP-N-acetylenolpyruvoylglucosamine reductase
Thiol:disulfide interchange protein DsbA
RNA 3'-terminal phosphate cyclase insert
Putative pyruvate, phosphate dikinase regulatory protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Formamidopyrimidine-DNA glycosylase catalytic
Cysteine sulfenic acid (-SOH) intermediate
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
RlpA-like protein double-psi beta-barrel
Transglutaminase-like domain-containing protein
Phosphatidylglycerol lysyltransferase C-terminal
Alginate export domain-containing protein
Anthranilate synthase component I N-terminal
Type I restriction modification DNA specificity
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
ATP-dependent Clp protease proteolytic subunit
Cobalt-precorrin-5B C(1)-methyltransferase
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
IgGFc-binding protein N-terminal domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
3-beta hydroxysteroid dehydrogenase/isomerase
Ribosomal RNA large subunit methyltransferase H
Sugar fermentation stimulation protein homolog
Methionyl-tRNA synthetase anticodon-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Involved in Mg(2+) ion dislocation from EF-Tu
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
2-dehydro-3-deoxyphosphooctonate aldolase
YbaK/aminoacyl-tRNA synthetase-associated
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Release factor glutamine methyltransferase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
DNA-directed DNA polymerase family A palm
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Molybdopterin cofactor biosynthesis C (MoaC)
Crossover junction endodeoxyribonuclease RuvC
4-hydroxy-tetrahydrodipicolinate reductase
Flagellar assembly protein FliH/Type III secretion system HrpE
Aminoacyl-tRNA synthetase class I anticodon-binding
Putative regulatory protein FmdB Zinc ribbon
Involved in ionization of N3 of dUMP, leading to its activation
3-methyl-2-oxobutanoate hydroxymethyltransferase
TRAP C4-dicarboxylate transport system permease DctM subunit
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Superoxide dismutase copper/zinc binding
Imidazole glycerol phosphate synthase subunit HisF
EfeO-type cupredoxin-like domain-containing protein
Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Formylmethanofuran dehydrogenase subunit E domain-containing protein
Glutamate synthase alpha subunit C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Peptide methionine sulphoxide reductase MsrA
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
RNA 2-O ribose methyltransferase substrate binding
NADH-rubredoxin oxidoreductase C-terminal
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein