2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
DNA replication/recombination mediator RecO N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Phosphomannose isomerase type I catalytic
Solute-binding protein family 5 domain-containing protein
Cation-transporting P-type ATPase N-terminal
Polysaccharide biosynthesis protein C-terminal
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Streptococcal pilin isopeptide linker domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Resolvase/invertase-type recombinase catalytic
Transposase IS116/IS110/IS902 C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Capsule synthesis protein CapA domain-containing protein
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
S-adenosylmethionine-dependent methyltransferase
Aminoacyl-transfer RNA synthetases class-II family profile
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Phosphotransferase system EIIB component type 2/3
Aspartate/homoserine dehydrogenase NAD-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Proton acceptor; for glutaminase activity
Glycosyltransferase subfamily 4-like N-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RNA polymerase sigma factor 70 region 4 type 2
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Exonuclease VII large subunit C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Prealbumin-like fold domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
Pyridoxamine 5'-phosphate oxidase putative
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Shikimate dehydrogenase substrate binding N-terminal
Solute-binding protein family 3/N-terminal
Diacylglycerol glucosyltransferase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cell envelope-related transcriptional attenuator
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Choloylglycine hydrolase/NAAA C-terminal
Phosphotransferase system enzyme I N-terminal
Sugar ABC transporter substrate-binding protein
Protein involved in sex pheromone biosynthesis
Aconitase A/isopropylmalate dehydratase small subunit swivel
Essential for prephenate dehydratase activity
ATP-dependent DNA helicase RecG C-terminal
SsuA/THI5-like domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Tryptophan synthase beta chain-like PALP
Important for beta-aspartyl-AMP intermediate formation
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
UDP-glucose/GDP-mannose dehydrogenase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Small ribosomal subunit protein uS4 N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glucose-6-phosphate isomerase prokaryote
Phosphoribosylformylglycinamidine synthase linker
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
N6 adenine-specific DNA methyltransferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Sodium/calcium exchanger membrane region
Penicillin-binding protein transpeptidase
Type I restriction modification DNA specificity
Gram-positive cocci surface proteins LPxTG domain-containing protein
Gram-positive pilin backbone subunit 2 Cna-B-like
Phosphatidic acid phosphatase type 2/haloperoxidase
NIF system FeS cluster assembly NifU N-terminal
CobB/CobQ-like glutamine amidotransferase
Prokaryotic-type class I peptide chain release factors
HPr(Ser) kinase/phosphorylase N-terminal
5-glutamyl coenzyme A thioester intermediate
SUF system FeS cluster assembly SufBD N-terminal
Transcription regulator AsnC/Lrp ligand binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ABC transporter substrate-binding protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Important for autoinhibition of adenylyltransferase activity
Ribose-phosphate pyrophosphokinase N-terminal
Release factor glutamine methyltransferase N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Gram-positive cocci surface proteins LPxTG
Helix-hairpin-helix DNA-binding motif class 1
Peptide ABC transporter substrate-binding protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Threonine/serine exporter-like N-terminal
DNA mismatch repair proteins mutS family
Thymidylate synthase/dCMP hydroxymethylase
Heat-inducible transcription repressor HrcA C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Mannose-6-phosphate isomerase type II C-terminal
ABC transporter substrate-binding protein PnrA-like
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptide methionine sulphoxide reductase MsrA
Membrane insertase YidC/Oxa/ALB C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein bL9 C-terminal
Schiff-base intermediate with acetaldehyde
Reversibly protonated during proton transport
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Large ribosomal subunit protein uL6 alpha-beta
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL15/eL18
Lysidine-tRNA(Ile) synthetase C-terminal
Translation elongation factor P/YeiP central
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Isopeptide-forming domain-containing fimbrial protein
YbaK/aminoacyl-tRNA synthetase-associated
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Gram-positive pilin subunit D1 N-terminal domain-containing protein
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase