Fimbrial-type adhesion domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Bacterial type II secretion system protein E
Membrane fusion protein biotin-lipoyl like
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Beta-lactamase hydrolase-like protein phosphatase-like
Septum formation inhibitor MinC C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
TonB-dependent receptor-like beta-barrel
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Solute-binding protein family 3/N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Involved in tetramerization or stability of the tetramer
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Anthranilate synthase component I N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Required for zinc-mediated homotetramerization and catalytic activity
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Major facilitator superfamily (MFS) profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA mismatch repair proteins mutS family
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Type VI secretion system IcmF C-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Chromosomal replication initiator DnaA C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
Tryptophan synthase beta chain-like PALP
Could be important to modulate the pK values of the two catalytic cysteine residues
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
ABC-type transport auxiliary lipoprotein component
Mandelate racemase/muconate lactonizing enzyme C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Release factor glutamine methyltransferase N-terminal
Disulphide bond isomerase DsbC/G N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Interacts with tRNA; defines subfamily-specific binding signature
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Aminoacyl-tRNA synthetase class I anticodon-binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Inner membrane protein YgaP-like transmembrane
S-adenosyl-L-homocysteine hydrolase NAD binding
Thymidylate synthase/dCMP hydroxymethylase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polysaccharide biosynthesis protein CapD-like
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Proteinase inhibitor I42 chagasin domain-containing protein
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
O-(5'-phospho-DNA)-tyrosine intermediate
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Virulence factor membrane-bound polymerase C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Type II secretion system protein GspI C-terminal
Outer membrane lipoprotein-sorting protein
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Autotransporter domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Secretin/TonB short N-terminal domain-containing protein
Chromosomal replication initiator protein DnaA
Electron transfer via tryptophanyl radical
Small ribosomal subunit protein uS4 N-terminal
Cation-transporting P-type ATPase N-terminal
Prepilin type IV endopeptidase peptidase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Type II secretion system protein GspG C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Ionotropic glutamate receptor C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Proton acceptor; for glutaminase activity
PapC N-terminal domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Outer membrane protein beta-barrel domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Essential for prephenate dehydratase activity
Peptidase S8/S53 domain-containing protein
DNA polymerase III delta subunit C-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-99)
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Molybdopterin cofactor biosynthesis C (MoaC)
Peptide methionine sulphoxide reductase MsrA
Survival protein SurE-like phosphatase/nucleotidase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Lipocalin-like domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycosyl transferase family 3 N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Polypeptide-transport-associated ShlB-type
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
RNA polymerase sigma factor 70 region 4 type 2
Polymerase/histidinol phosphatase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Quercetin 2,3-dioxygenase C-terminal cupin
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Large ribosomal subunit protein uL15/eL18
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyruvate phosphate dikinase AMP/ATP-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase E methyltransferase
RlpA-like protein double-psi beta-barrel
Large ribosomal subunit protein uL2 C-terminal
Bacterial OB-fold domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Glycine cleavage T-protein C-terminal barrel
Prokaryotic-type class I peptide chain release factors
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glycine zipper 2TM domain-containing protein
Trimeric autotransporter adhesin YadA-like head
Nitrite/Sulfite reductase ferredoxin-like
Ricin B lectin domain-containing protein
Trimeric autotransporter adhesin YadA-like stalk
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Putative regulatory protein FmdB Zinc ribbon
Large ribosomal subunit protein uL6 alpha-beta
Membrane insertase YidC/Oxa/ALB C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Outer-membrane lipoprotein carrier protein
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein bL25 L25
Gp5/Type VI secretion system Vgr protein OB-fold
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
RNA 2-O ribose methyltransferase substrate binding
Interaction with polymerase core subunit RpoC
Important for interaction with partner proteins
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polysaccharide chain length determinant N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Carbamoyl-phosphate synthase small subunit N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA-directed DNA polymerase family A palm
Outer membrane protein assembly factor BamA
Pseudouridine synthase I TruA alpha/beta
Plays an important role in substrate specificity
Superoxide dismutase copper/zinc binding
NIF system FeS cluster assembly NifU C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Integral membrane protein YccS N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Translation elongation factor P/YeiP central
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Regulator of nucleoside diphosphate kinase N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Heme-copper oxidase subunit III family profile
Ribosomal RNA small subunit methyltransferase E PUA-like
N-end rule aminoacyl transferase C-terminal
Reversibly protonated during proton transport
NIF system FeS cluster assembly NifU N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Alpha-carbonic anhydrase domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal