9103:CPB1
gene id: 9103:CPB1
uniprot id: G1N4I9
names: Similarity
messages: Belongs to the peptidase M14 family.

9103:GTPBP4
gene id: 9103:GTPBP4
uniprot id: H9H2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9103:BET1L
gene id: 9103:BET1L
uniprot id: G1MUQ0
names: Subcellular Location Annotation
messages: Membrane

9103:NRTN
gene id: 9103:NRTN
uniprot id: A0A803YNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9103:SLC1A2
gene id: 9103:SLC1A2
uniprot id: G1ND48
uniprot id: G3US00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9103:SH3RF1
gene id: 9103:SH3RF1
uniprot id: G1MUP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

9103:VPS37B
gene id: 9103:VPS37B
uniprot id: A0A803XY54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9103:MED22
gene id: 9103:MED22
uniprot id: G1N3R2
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9103:LOC100551319
gene id: 9103:LOC100551319
uniprot id: G1ND93
names: Similarity
messages: Belongs to the serpin family.

9103:SGCD
gene id: 9103:SGCD
uniprot id: A0A803YRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9103:GPR89B
gene id: 9103:GPR89B
uniprot id: G3URY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

9103:TTC21B
gene id: 9103:TTC21B
uniprot id: G1NE60
uniprot id: G3UPS4
names: Similarity
messages: Belongs to the TTC21 family.

9103:DIO1
gene id: 9103:DIO1
uniprot id: M9P2D6
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9103:STX6
gene id: 9103:STX6
uniprot id: A0A803Y3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

9103:ZER1
gene id: 9103:ZER1
uniprot id: G1MZK3
names: Similarity
messages: Belongs to the zyg-11 family.

9103:ST3GAL6
gene id: 9103:ST3GAL6
uniprot id: G1NNG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:VDAC2
gene id: 9103:VDAC2
uniprot id: G3X8N2
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9103:SUPV3L1
gene id: 9103:SUPV3L1
uniprot id: G1MYL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

9103:NIPAL1
gene id: 9103:NIPAL1
uniprot id: G1NHH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9103:MCM2
gene id: 9103:MCM2
uniprot id: G3UP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

9103:F13A1
gene id: 9103:F13A1
uniprot id: G1MXW0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9103:LOC100538454
gene id: 9103:LOC100538454
uniprot id: H9H278
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100541666
gene id: 9103:LOC100541666
uniprot id: G1N764
names: Similarity
messages: Belongs to the peptidase C14A family.

9103:PSAP
gene id: 9103:PSAP
uniprot id: G1MZV1
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

9103:PRF1
gene id: 9103:PRF1
uniprot id: G1MQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

9103:NFE2L2
gene id: 9103:NFE2L2
uniprot id: G3UU95
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9103:UTS2B
gene id: 9103:UTS2B
uniprot id: G1N642
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

9103:BPGM
gene id: 9103:BPGM
uniprot id: G1NLB3
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9103:CPLX2
gene id: 9103:CPLX2
uniprot id: G1MZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9103:SDC4
gene id: 9103:SDC4
uniprot id: Q5I5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9103:TPX2
gene id: 9103:TPX2
uniprot id: G1N5U0
uniprot id: G3URR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

9103:DLK1
gene id: 9103:DLK1
uniprot id: B3VL40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ATP6V0A4
gene id: 9103:ATP6V0A4
uniprot id: A0A803Y6J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:TOM1
gene id: 9103:TOM1
uniprot id: G1NJE2
names: Similarity
messages: Belongs to the TOM1 family.

9103:LOC104911326
gene id: 9103:LOC104911326
uniprot id: G1MVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9103:CGA
gene id: 9103:CGA
uniprot id: P68241
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. Glycoprotein hormones are heterodimers composed of a common alpha chain described here and a unique beta chain which confers their biological specificity to the different hormones.
messages: Secreted
messages: Shared alpha chain of heterodimeric glycoprotein hormones. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

9103:ATE1
gene id: 9103:ATE1
uniprot id: A0A803XLY2
uniprot id: A0A803XPL6
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

9103:HSF4
gene id: 9103:HSF4
uniprot id: G1MQD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9103:LOC100543754
gene id: 9103:LOC100543754
uniprot id: A0A803YIS5
uniprot id: G1NP55
names: Subcellular Location Annotation
messages: Membrane

9103:FAM20B
gene id: 9103:FAM20B
uniprot id: G1MUV3
names: Similarity
messages: Belongs to the FAM20 family.

9103:CTSC
gene id: 9103:CTSC
uniprot id: G1NQP8
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

9103:KCNJ2
gene id: 9103:KCNJ2
uniprot id: G1N4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

9103:LOC100547911
gene id: 9103:LOC100547911
uniprot id: A0A803XW69
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9103:CCND1
gene id: 9103:CCND1
uniprot id: G1NC37
names: Similarity
messages: Belongs to the cyclin family.

9103:KCNE1
gene id: 9103:KCNE1
uniprot id: G1NS78
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the potassium channel KCNE family.
messages: Cell membrane
messages: Membrane

9103:MMAA
gene id: 9103:MMAA
uniprot id: G1MXD1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

9103:CREM
gene id: 9103:CREM
uniprot id: G1N2F5
names: Subcellular Location Annotation
messages: Nucleus

9103:SLC24A5
gene id: 9103:SLC24A5
uniprot id: G1N503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9103:VWA2
gene id: 9103:VWA2
uniprot id: G1NF03
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC109367190
gene id: 9103:LOC109367190
uniprot id: A0A803XXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9103:SF3B1
gene id: 9103:SF3B1
uniprot id: G1N5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

9103:TRPV1
gene id: 9103:TRPV1
uniprot id: G1N4J0
names: Subcellular Location Annotation
messages: Membrane

9103:NMUR1
gene id: 9103:NMUR1
uniprot id: G1N7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

9103:CDH11
gene id: 9103:CDH11
uniprot id: G1N438
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9103:LOC100550136
gene id: 9103:LOC100550136
uniprot id: G1MW46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

9103:RPL21
gene id: 9103:RPL21
uniprot id: G1NQD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9103:BIRC7
gene id: 9103:BIRC7
uniprot id: A0A803XTE3
uniprot id: G1N383
names: Similarity
messages: Belongs to the IAP family.

9103:P2RX7
gene id: 9103:P2RX7
uniprot id: G1MY55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9103:LOC100544408
gene id: 9103:LOC100544408
uniprot id: G1N766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

9103:BID
gene id: 9103:BID
uniprot id: G1NL76
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

9103:APOO
gene id: 9103:APOO
uniprot id: G1NP80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9103:PPP6R2
gene id: 9103:PPP6R2
uniprot id: A0A803YFT8
uniprot id: G1MZ26
names: Similarity
messages: Belongs to the SAPS family.

9103:WDR35
gene id: 9103:WDR35
uniprot id: A0A803Y4B8
uniprot id: G1NMM8
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

9103:CNTN2
gene id: 9103:CNTN2
uniprot id: G1MQQ9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

9103:ZHX1
gene id: 9103:ZHX1
uniprot id: G1NIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

9103:HAPLN3
gene id: 9103:HAPLN3
uniprot id: G1N954
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:FGF7
gene id: 9103:FGF7
uniprot id: A0A803YL51
uniprot id: G1N5T3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9103:LOC100538694
gene id: 9103:LOC100538694
uniprot id: G1N6B2
uniprot id: Q71SZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

9103:NIPA1
gene id: 9103:NIPA1
uniprot id: G1NPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9103:SNX1
gene id: 9103:SNX1
uniprot id: G1MRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

9103:SPTB
gene id: 9103:SPTB
uniprot id: G1MZL4
names: Similarity
messages: Belongs to the spectrin family.

9103:AVPR1B
gene id: 9103:AVPR1B
uniprot id: G1MWJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

9103:SYT17
gene id: 9103:SYT17
uniprot id: G1N792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

9103:NDRG1
gene id: 9103:NDRG1
uniprot id: G1NJN8
names: Similarity
messages: Belongs to the NDRG family.

9103:ERO1A
gene id: 9103:ERO1A
uniprot id: G1NM09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

9103:NR1D2
gene id: 9103:NR1D2
uniprot id: G1NEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9103:LOC100540050
gene id: 9103:LOC100540050
uniprot id: G1NRI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:LOC100539852
gene id: 9103:LOC100539852
uniprot id: G1NRX3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:C23H1orf174
gene id: 9103:C23H1orf174
uniprot id: G1MS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

9103:RNF34
gene id: 9103:RNF34
uniprot id: G1MYN1
names: Subcellular Location Annotation
messages: Cell membrane

9103:ND6
gene id: 9103:ND6
uniprot id: F1JUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

9103:PSMA2
gene id: 9103:PSMA2
uniprot id: G1NI68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9103:DMC1
gene id: 9103:DMC1
uniprot id: G1NIK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. DMC1 subfamily.
messages: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
messages: Nucleus

9103:LOC100542077
gene id: 9103:LOC100542077
uniprot id: G1NRP6
names: Similarity
messages: Belongs to the TENT family.

9103:CZH5orf63
gene id: 9103:CZH5orf63
uniprot id: A0A803YPF3
names: Similarity
messages: Belongs to the glutaredoxin family.

9103:RASGRP3
gene id: 9103:RASGRP3
uniprot id: G1NEU8
names: Similarity
messages: Belongs to the RASGRP family.

9103:FAM102B
gene id: 9103:FAM102B
uniprot id: G1N371
names: Similarity
messages: Belongs to the EEIG family.

9103:ACTN1
gene id: 9103:ACTN1
uniprot id: G1NH44
names: Similarity
messages: Belongs to the alpha-actinin family.

9103:ITGB8
gene id: 9103:ITGB8
uniprot id: A0A803XU91
uniprot id: G1NFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9103:UTP11
gene id: 9103:UTP11
uniprot id: G1MV44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9103:NSUN6
gene id: 9103:NSUN6
uniprot id: G1N692
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9103:PPP6C
gene id: 9103:PPP6C
uniprot id: G1N8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

9103:NETO1
gene id: 9103:NETO1
uniprot id: G1N880
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:EIF2B5
gene id: 9103:EIF2B5
uniprot id: G1N9P1
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

9103:CILP
gene id: 9103:CILP
uniprot id: G1NBA9
names: Subcellular Location Annotation
messages: extracellular matrix

9103:LOC100548295
gene id: 9103:LOC100548295
uniprot id: G1N3Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9103:TFDP1
gene id: 9103:TFDP1
uniprot id: G1NPR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9103:CHRNA9
gene id: 9103:CHRNA9
uniprot id: G1NI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:LOC100549708
gene id: 9103:LOC100549708
uniprot id: G1NHE5
names: Similarity
messages: Belongs to the globin family.

9103:NUDT21
gene id: 9103:NUDT21
uniprot id: G1MQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

9103:RHCE
gene id: 9103:RHCE
uniprot id: G1MSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9103:AGBL1
gene id: 9103:AGBL1
uniprot id: A0A803Y4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9103:TNNT3
gene id: 9103:TNNT3
uniprot id: Q9DE11
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9103:TUBGCP6
gene id: 9103:TUBGCP6
uniprot id: A0A803Y1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

9103:TEKT4
gene id: 9103:TEKT4
uniprot id: G1N166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

9103:GNB5
gene id: 9103:GNB5
uniprot id: A0A803YG17
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9103:LOC100539135
gene id: 9103:LOC100539135
uniprot id: A0A803XPE6
uniprot id: G3UUW5
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

9103:CACNG2
gene id: 9103:CACNG2
uniprot id: G1NJ55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

9103:TMC6
gene id: 9103:TMC6
uniprot id: G1N272
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9103:LOC723980
gene id: 9103:LOC723980
uniprot id: G1MSZ9
names: Similarity
messages: Belongs to the avidin/streptavidin family.

9103:LOC104911020
gene id: 9103:LOC104911020
uniprot id: A0A803XXC3
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

9103:CYGB
gene id: 9103:CYGB
uniprot id: G1MYC6
names: Similarity
messages: Belongs to the globin family.

9103:AP2B1
gene id: 9103:AP2B1
uniprot id: G1MY27
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9103:OTULINL
gene id: 9103:OTULINL
uniprot id: G1N2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9103:ACYP1
gene id: 9103:ACYP1
uniprot id: G1NJC9
names: Similarity
messages: Belongs to the acylphosphatase family.

9103:SERPINA1
gene id: 9103:SERPINA1
uniprot id: G1NKH9
names: Similarity
messages: Belongs to the serpin family.

9103:LOC100547278
gene id: 9103:LOC100547278
uniprot id: A0A803YFI4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

9103:ADSL
gene id: 9103:ADSL
uniprot id: G1NIA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

9103:OSBPL8
gene id: 9103:OSBPL8
uniprot id: A0A803Y7J2
names: Similarity
messages: Belongs to the OSBP family.

9103:FTSJ3
gene id: 9103:FTSJ3
uniprot id: G1MQL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

9103:ACTN2
gene id: 9103:ACTN2
uniprot id: A0A803Y9V3
names: Similarity
messages: Belongs to the alpha-actinin family.

9103:NSMCE1
gene id: 9103:NSMCE1
uniprot id: G1N4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

9103:INO80
gene id: 9103:INO80
uniprot id: G1NF95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

9103:LOC100540595
gene id: 9103:LOC100540595
uniprot id: G3USS3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9103:GNB4
gene id: 9103:GNB4
uniprot id: G1MU86
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9103:TMEM151B
gene id: 9103:TMEM151B
uniprot id: G1NRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

9103:SH3BGRL2
gene id: 9103:SH3BGRL2
uniprot id: A0A803YHI0
names: Similarity
messages: Belongs to the SH3BGR family.

9103:TBL1X
gene id: 9103:TBL1X
uniprot id: G1NPE9
names: Similarity
messages: Belongs to the WD repeat EBI family.

9103:MFNG
gene id: 9103:MFNG
uniprot id: A0A803Y789
names: Subcellular Location Annotation
messages: Membrane

9103:MYOF
gene id: 9103:MYOF
uniprot id: A0A803YE64
uniprot id: G1N9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9103:TSPAN1
gene id: 9103:TSPAN1
uniprot id: G1NDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9103:PPM1B
gene id: 9103:PPM1B
uniprot id: G3UR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

9103:MRPL15
gene id: 9103:MRPL15
uniprot id: G1NEM9
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9103:MRPL50
gene id: 9103:MRPL50
uniprot id: G1NS09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

9103:TASOR2
gene id: 9103:TASOR2
uniprot id: A0A803YQR8
names: Similarity
messages: Belongs to the TASOR family.

9103:GLI1
gene id: 9103:GLI1
uniprot id: A0A803XYT2
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9103:LSM7
gene id: 9103:LSM7
uniprot id: A0A803YJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

9103:SLC52A3
gene id: 9103:SLC52A3
uniprot id: G1MQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9103:RMI1
gene id: 9103:RMI1
uniprot id: G1NS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

9103:LOC100538525
gene id: 9103:LOC100538525
uniprot id: A0A803XM99
names: Similarity
messages: Belongs to the DeSI family.

9103:THBS2
gene id: 9103:THBS2
uniprot id: G1NI19
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TMEM120B
gene id: 9103:TMEM120B
uniprot id: G1MYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

9103:AP5M1
gene id: 9103:AP5M1
uniprot id: G1NLK4
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

9103:CDCA7L
gene id: 9103:CDCA7L
uniprot id: G5E7K9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:KATNAL1
gene id: 9103:KATNAL1
uniprot id: G1NQC0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9103:SLC25A42
gene id: 9103:SLC25A42
uniprot id: A0A803Y9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:EGF
gene id: 9103:EGF
uniprot id: G1NEX1
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ASXL2
gene id: 9103:ASXL2
uniprot id: G1NMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

9103:USP15
gene id: 9103:USP15
uniprot id: A0A803XU98
uniprot id: G5E7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

9103:STOM
gene id: 9103:STOM
uniprot id: G1N774
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9103:ZBED4
gene id: 9103:ZBED4
uniprot id: A0A803XZF3
names: Subcellular Location Annotation
messages: Nucleus

9103:RPS3
gene id: 9103:RPS3
uniprot id: A0A803XL13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

9103:FAM83G
gene id: 9103:FAM83G
uniprot id: G1N0P6
names: Similarity
messages: Belongs to the FAM83 family.

9103:LOC100550719
gene id: 9103:LOC100550719
uniprot id: A0A803YNS9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

9103:LOC100548577
gene id: 9103:LOC100548577
uniprot id: A0A803YL44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the noggin family.
messages: Secreted

9103:WNT7A
gene id: 9103:WNT7A
uniprot id: G1N1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9103:ARL6IP4
gene id: 9103:ARL6IP4
uniprot id: G1MWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

9103:PRPH2
gene id: 9103:PRPH2
uniprot id: G1NC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

9103:RPL19
gene id: 9103:RPL19
uniprot id: G1N109
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

9103:GATA3
gene id: 9103:GATA3
uniprot id: G1MZ75
names: Subcellular Location Annotation
messages: Nucleus

9103:PIGO
gene id: 9103:PIGO
uniprot id: A0A803YD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:ACOX3
gene id: 9103:ACOX3
uniprot id: G1NJP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9103:PLXNA4
gene id: 9103:PLXNA4
uniprot id: G1MXM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:GSG1
gene id: 9103:GSG1
uniprot id: A0A803YE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

9103:C17H12orf49
gene id: 9103:C17H12orf49
uniprot id: G1NCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

9103:SUGP2
gene id: 9103:SUGP2
uniprot id: G1MZ65
names: Subcellular Location Annotation
messages: Nucleus

9103:BCDIN3D
gene id: 9103:BCDIN3D
uniprot id: A0A803XSA0
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9103:EML4
gene id: 9103:EML4
uniprot id: A0A803Y4G7
uniprot id: A0A803YBK2
uniprot id: A0A803YFB9
uniprot id: A0A803YM71
names: Similarity
messages: Belongs to the WD repeat EMAP family.

9103:YIPF7
gene id: 9103:YIPF7
uniprot id: G1NHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9103:ANKRD13A
gene id: 9103:ANKRD13A
uniprot id: G1N439
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9103:SERPINH1
gene id: 9103:SERPINH1
uniprot id: G3UT05
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

9103:MATK
gene id: 9103:MATK
uniprot id: G1MQF2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9103:NCSTN
gene id: 9103:NCSTN
uniprot id: H9H0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

9103:MFSD11
gene id: 9103:MFSD11
uniprot id: G3UTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9103:FAR2
gene id: 9103:FAR2
uniprot id: A0A803YBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9103:LOC104914326
gene id: 9103:LOC104914326
uniprot id: A0A803YE52
names: Subcellular Location Annotation
messages: Membrane

9103:SLC15A1
gene id: 9103:SLC15A1
uniprot id: Q802B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9103:SLC5A12
gene id: 9103:SLC5A12
uniprot id: G1MSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9103:BLCAP
gene id: 9103:BLCAP
uniprot id: G1NR85
names: Similarity
messages: Belongs to the BLCAP family.

9103:PSMA6
gene id: 9103:PSMA6
uniprot id: G1NIQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9103:STXBP3
gene id: 9103:STXBP3
uniprot id: G1NEL2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9103:ATP23
gene id: 9103:ATP23
uniprot id: G1NCB2
names: Similarity
messages: Belongs to the peptidase M76 family.

9103:NIPSNAP2
gene id: 9103:NIPSNAP2
uniprot id: G3US30
names: Similarity
messages: Belongs to the NipSnap family.

9103:PRRC1
gene id: 9103:PRRC1
uniprot id: A0A803Y1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

9103:GNPDA2
gene id: 9103:GNPDA2
uniprot id: G1NHQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9103:PDE6D
gene id: 9103:PDE6D
uniprot id: G1N7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

9103:UBA3
gene id: 9103:UBA3
uniprot id: G1NB02
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

9103:AURKA
gene id: 9103:AURKA
uniprot id: G1NAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

9103:ATP5MC3
gene id: 9103:ATP5MC3
uniprot id: H9H1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

9103:LOC100542828
gene id: 9103:LOC100542828
uniprot id: G1NPM8
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9103:TAS1R3
gene id: 9103:TAS1R3
uniprot id: G1MVJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:MAPKAP1
gene id: 9103:MAPKAP1
uniprot id: G1N8V8
names: Similarity
messages: Belongs to the SIN1 family.

9103:TSC22D2
gene id: 9103:TSC22D2
uniprot id: A0A803YCQ9
uniprot id: G1NEP1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9103:LOC100548708
gene id: 9103:LOC100548708
uniprot id: G1N971
names: Similarity
messages: Belongs to the CLCR family.

9103:LOC100539006
gene id: 9103:LOC100539006
uniprot id: G1N9H8
names: Similarity
messages: Belongs to the globin family.

9103:RACK1
gene id: 9103:RACK1
uniprot id: B1N1C2
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

9103:LOC100544899
gene id: 9103:LOC100544899
uniprot id: G1N1U5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9103:PACSIN2
gene id: 9103:PACSIN2
uniprot id: G1NLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

9103:CMC1
gene id: 9103:CMC1
uniprot id: G1NF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9103:SLC35B4
gene id: 9103:SLC35B4
uniprot id: G1MX80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9103:ZNF326
gene id: 9103:ZNF326
uniprot id: G1N8P6
names: Similarity
messages: Belongs to the AKAP95 family.

9103:PAMR1
gene id: 9103:PAMR1
uniprot id: A0A803XQD5
uniprot id: G1ND63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GCGR
gene id: 9103:GCGR
uniprot id: G1N1K7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:MRPS15
gene id: 9103:MRPS15
uniprot id: G1MWW2
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

9103:LOC100544485
gene id: 9103:LOC100544485
uniprot id: G1NQJ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9103:EPHA7
gene id: 9103:EPHA7
uniprot id: G1NLJ3
names: Subcellular Location Annotation
messages: Membrane

9103:GAREM1
gene id: 9103:GAREM1
uniprot id: G1NDS3
names: Similarity
messages: Belongs to the GAREM family.

9103:LPAR3
gene id: 9103:LPAR3
uniprot id: G1NA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:MVD
gene id: 9103:MVD
uniprot id: A0A803YBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
messages: Nucleus

9103:LOC104912586
gene id: 9103:LOC104912586
uniprot id: A0A803XN85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9103:AXIN1
gene id: 9103:AXIN1
uniprot id: G1N9T5
names: Subcellular Location Annotation
messages: Cytoplasm

9103:ATG4C
gene id: 9103:ATG4C
uniprot id: G1NGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

9103:CEMIP
gene id: 9103:CEMIP
uniprot id: G1N7U1
names: Similarity
messages: Belongs to the CEMIP family.

9103:LOC100126556
gene id: 9103:LOC100126556
uniprot id: A7WPR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:GDAP2
gene id: 9103:GDAP2
uniprot id: G1NN58
names: Similarity
messages: Belongs to the GDAP2 family.

9103:LOC100548817
gene id: 9103:LOC100548817
uniprot id: G1NR58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:PTPN21
gene id: 9103:PTPN21
uniprot id: G1NK10
uniprot id: G3X8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9103:PICALM
gene id: 9103:PICALM
uniprot id: A0A803XPW2
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

9103:MAFK
gene id: 9103:MAFK
uniprot id: G1MUM2
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9103:LOC100547944
gene id: 9103:LOC100547944
uniprot id: G1NDJ8
names: Similarity
messages: Belongs to the folate receptor family.

9103:MON1A
gene id: 9103:MON1A
uniprot id: G1MUS3
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

9103:ARHGDIA
gene id: 9103:ARHGDIA
uniprot id: G1N1C7
names: Similarity
messages: Belongs to the Rho GDI family.

9103:VIRMA
gene id: 9103:VIRMA
uniprot id: G1NHI1
names: Similarity
messages: Belongs to the vir family.

9103:CLP1
gene id: 9103:CLP1
uniprot id: G1NBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

9103:HIGD1A
gene id: 9103:HIGD1A
uniprot id: G1MU31
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9103:KIN
gene id: 9103:KIN
uniprot id: G1MYZ9
names: Similarity
messages: Belongs to the KIN17 family.

9103:HVCN1
gene id: 9103:HVCN1
uniprot id: G1N0J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

9103:LOC100538839
gene id: 9103:LOC100538839
uniprot id: G1NE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9103:LOC100541463
gene id: 9103:LOC100541463
uniprot id: G3UPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

9103:LOC100539008
gene id: 9103:LOC100539008
uniprot id: G1MTV2
names: Similarity
messages: Belongs to the glutamine synthetase family.

9103:SLC6A6
gene id: 9103:SLC6A6
uniprot id: A0A803Y1T5
uniprot id: A0A803YCI0
uniprot id: G1N750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

9103:CACNG1
gene id: 9103:CACNG1
uniprot id: G1N671
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

9103:ZDHHC22
gene id: 9103:ZDHHC22
uniprot id: G1NJK6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:TRMT5
gene id: 9103:TRMT5
uniprot id: G1NLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

9103:PCNX4
gene id: 9103:PCNX4
uniprot id: G1NLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

9103:PDGFRL
gene id: 9103:PDGFRL
uniprot id: G1NGA0
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

9103:YWHAQ
gene id: 9103:YWHAQ
uniprot id: G3UUP5
names: Similarity
messages: Belongs to the 14-3-3 family.

9103:KATNAL2
gene id: 9103:KATNAL2
uniprot id: A0A803Y023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

9103:TPPP3
gene id: 9103:TPPP3
uniprot id: H9H2H9
names: Similarity
messages: Belongs to the TPPP family.

9103:PLSCR1
gene id: 9103:PLSCR1
uniprot id: G1N4E3
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9103:APOLD1
gene id: 9103:APOLD1
uniprot id: G1NRJ2
names: Similarity
messages: Belongs to the apolipoprotein L family.

9103:ABCC9
gene id: 9103:ABCC9
uniprot id: A0A803YDU9
uniprot id: G1NLN2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

9103:DENND10
gene id: 9103:DENND10
uniprot id: G1NFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

9103:ODR4
gene id: 9103:ODR4
uniprot id: G1MR07
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

9103:FZR1
gene id: 9103:FZR1
uniprot id: G1MRR2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9103:NDUFAF1
gene id: 9103:NDUFAF1
uniprot id: G1NFC0
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

9103:CDC42EP3
gene id: 9103:CDC42EP3
uniprot id: G1NRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9103:SLC4A10
gene id: 9103:SLC4A10
uniprot id: A0A803XZL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

9103:RAB32
gene id: 9103:RAB32
uniprot id: G1NIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9103:STXBP5
gene id: 9103:STXBP5
uniprot id: G1NIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9103:CKAP2L
gene id: 9103:CKAP2L
uniprot id: A0A803Y4M2
names: Similarity
messages: Belongs to the CKAP2 family.

9103:LOC100541513
gene id: 9103:LOC100541513
uniprot id: G1N736
names: Similarity
messages: Belongs to the peptidase C14A family.

9103:LOC100551422
gene id: 9103:LOC100551422
uniprot id: G1N5L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

9103:NFRKB
gene id: 9103:NFRKB
uniprot id: G1MQZ7
names: Subcellular Location Annotation
messages: Nucleus

9103:KMT5B
gene id: 9103:KMT5B
uniprot id: G1NAG9
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9103:TMOD4
gene id: 9103:TMOD4
uniprot id: G1MQX4
names: Subcellular Location Annotation
messages: cytoskeleton

9103:RNF146
gene id: 9103:RNF146
uniprot id: A0A803Y8R8
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

9103:LOC100541871
gene id: 9103:LOC100541871
uniprot id: G1N1X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:SFRP2
gene id: 9103:SFRP2
uniprot id: G1MRC5
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100540154
gene id: 9103:LOC100540154
uniprot id: G1MUL3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9103:LOC100543905
gene id: 9103:LOC100543905
uniprot id: G1NRI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:FABP2
gene id: 9103:FABP2
uniprot id: G1NE55
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:SPPL2A
gene id: 9103:SPPL2A
uniprot id: G3UTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

9103:KDELR3
gene id: 9103:KDELR3
uniprot id: G1NII3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:GLRA2
gene id: 9103:GLRA2
uniprot id: A0A803Y0W2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

9103:IL16
gene id: 9103:IL16
uniprot id: A0A803Y9M7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

9103:TTYH2
gene id: 9103:TTYH2
uniprot id: G1N3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

9103:LAMP3
gene id: 9103:LAMP3
uniprot id: G1NB36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9103:SPOPL
gene id: 9103:SPOPL
uniprot id: G1NIU5
names: Similarity
messages: Belongs to the Tdpoz family.

9103:CORO1C
gene id: 9103:CORO1C
uniprot id: G1N2E7
names: Similarity
messages: Belongs to the WD repeat coronin family.

9103:TDP2
gene id: 9103:TDP2
uniprot id: G1N7I1
names: Subcellular Location Annotation
messages: PML body

9103:SLC39A12
gene id: 9103:SLC39A12
uniprot id: A0A803YE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

9103:GADD45G
gene id: 9103:GADD45G
uniprot id: A0A803Y5H9
names: Similarity
messages: Belongs to the GADD45 family.

9103:IARS1
gene id: 9103:IARS1
uniprot id: A0A803XNN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9103:PAX5
gene id: 9103:PAX5
uniprot id: A0A803XUE3
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100540332
gene id: 9103:LOC100540332
uniprot id: G1MTF8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9103:SCAP
gene id: 9103:SCAP
uniprot id: A0A803YMH6
uniprot id: G1MS81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

9103:YOD1
gene id: 9103:YOD1
uniprot id: G1NRG4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

9103:MEGF10
gene id: 9103:MEGF10
uniprot id: A0A803Y022
uniprot id: G1N7B5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:MBOAT1
gene id: 9103:MBOAT1
uniprot id: G1MUH6
names: Subcellular Location Annotation
messages: Membrane

9103:TP53INP1
gene id: 9103:TP53INP1
uniprot id: G1NHN1
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

9103:LNPK
gene id: 9103:LNPK
uniprot id: G1NBK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

9103:FUT7
gene id: 9103:FUT7
uniprot id: G1MR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

9103:ALG9
gene id: 9103:ALG9
uniprot id: G1MZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC104912152
gene id: 9103:LOC104912152
uniprot id: G1MUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

9103:NT5C3A
gene id: 9103:NT5C3A
uniprot id: G3UQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9103:MAFA
gene id: 9103:MAFA
uniprot id: G1NK14
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9103:LOC100547331
gene id: 9103:LOC100547331
uniprot id: G1MXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9103:MCTS1
gene id: 9103:MCTS1
uniprot id: A0A803YK75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

9103:HYLS1
gene id: 9103:HYLS1
uniprot id: G1MQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

9103:TRAPPC2
gene id: 9103:TRAPPC2
uniprot id: G1NPC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

9103:TENT5C
gene id: 9103:TENT5C
uniprot id: G1NS30
names: Similarity
messages: Belongs to the TENT family.

9103:LOC100542551
gene id: 9103:LOC100542551
uniprot id: A0A803YLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9103:GJA1
gene id: 9103:GJA1
uniprot id: G1NKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9103:TMEM50A
gene id: 9103:TMEM50A
uniprot id: G1MT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

9103:KDM4A
gene id: 9103:KDM4A
uniprot id: G1NC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

9103:FOXN4
gene id: 9103:FOXN4
uniprot id: G1N344
names: Subcellular Location Annotation
messages: Nucleus

9103:SEC23A
gene id: 9103:SEC23A
uniprot id: G1NIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9103:LIMK2
gene id: 9103:LIMK2
uniprot id: A0A803XKV3
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

9103:LOC100540904
gene id: 9103:LOC100540904
uniprot id: A0A803YFN1
uniprot id: G1N9X3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:UNC93A
gene id: 9103:UNC93A
uniprot id: G1NJJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9103:GNB3
gene id: 9103:GNB3
uniprot id: G1NMV3
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9103:KCNG2
gene id: 9103:KCNG2
uniprot id: G1MTI1
names: Subcellular Location Annotation
messages: Membrane

9103:COPB1
gene id: 9103:COPB1
uniprot id: G1N4E1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9103:ADAMTS10
gene id: 9103:ADAMTS10
uniprot id: G1MSN8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9103:PTPN22
gene id: 9103:PTPN22
uniprot id: G1N1U7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

9103:LOC100546187
gene id: 9103:LOC100546187
uniprot id: G1NCT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

9103:RPL5
gene id: 9103:RPL5
uniprot id: G1N7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

9103:LOC100543260
gene id: 9103:LOC100543260
uniprot id: G1MUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

9103:MED10
gene id: 9103:MED10
uniprot id: G1N3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9103:SSU72
gene id: 9103:SSU72
uniprot id: G1MUU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

9103:CPPED1
gene id: 9103:CPPED1
uniprot id: G1MQH3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

9103:PTGES
gene id: 9103:PTGES
uniprot id: A0A803XUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

9103:G6PC2
gene id: 9103:G6PC2
uniprot id: G1NDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9103:TIMP3
gene id: 9103:TIMP3
uniprot id: G1NJF8
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9103:RAD21L1
gene id: 9103:RAD21L1
uniprot id: G1N7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9103:LOC104913500
gene id: 9103:LOC104913500
uniprot id: G1MUW0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:DHRS7B
gene id: 9103:DHRS7B
uniprot id: A0A803Y7D8
uniprot id: G1MYK1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:LOC104914146
gene id: 9103:LOC104914146
uniprot id: G1MV19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:TBXT
gene id: 9103:TBXT
uniprot id: G1NIA4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9103:MAD1L1
gene id: 9103:MAD1L1
uniprot id: G1MUQ9
names: Similarity
messages: Belongs to the MAD1 family.

9103:LOC100544886
gene id: 9103:LOC100544886
uniprot id: A0A803XSA4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9103:PHKG1
gene id: 9103:PHKG1
uniprot id: G1MZ21
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

9103:FAM49B
gene id: 9103:FAM49B
uniprot id: A0A803XVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

9103:LOC100551469
gene id: 9103:LOC100551469
uniprot id: G1MZ37
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9103:LOC100546811
gene id: 9103:LOC100546811
uniprot id: G1N1J2
names: Similarity
messages: Belongs to the SUA5 family.

9103:AP1S3
gene id: 9103:AP1S3
uniprot id: A0A803XZI3
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

9103:PHETA2
gene id: 9103:PHETA2
uniprot id: G1NRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

9103:OSTC
gene id: 9103:OSTC
uniprot id: G3X8M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9103:CCR9
gene id: 9103:CCR9
uniprot id: A0A803YJ08
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:ACVR1C
gene id: 9103:ACVR1C
uniprot id: G1NJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9103:LOC100546606
gene id: 9103:LOC100546606
uniprot id: A0A803YSY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:SGSM2
gene id: 9103:SGSM2
uniprot id: A0A803XLP3
uniprot id: G1N8X1
names: Similarity
messages: Belongs to the RUTBC family.

9103:LECT2
gene id: 9103:LECT2
uniprot id: G3URY4
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

9103:PDE1C
gene id: 9103:PDE1C
uniprot id: A0A803Y584
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:CPSF3
gene id: 9103:CPSF3
uniprot id: G1NMJ4
names: Subcellular Location Annotation
messages: Nucleus

9103:DESI1
gene id: 9103:DESI1
uniprot id: G1NHS7
names: Similarity
messages: Belongs to the DeSI family.

9103:GATB
gene id: 9103:GATB
uniprot id: G1MYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

9103:LOC100549463
gene id: 9103:LOC100549463
uniprot id: G1NDI9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:HTR3A
gene id: 9103:HTR3A
uniprot id: G1MVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane

9103:RPL32
gene id: 9103:RPL32
uniprot id: G1NCW3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

9103:LOC104909322
gene id: 9103:LOC104909322
uniprot id: A0A803XLT5
uniprot id: A0A803Y2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: extracellular matrix

9103:RSPH3
gene id: 9103:RSPH3
uniprot id: G1NJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

9103:LOC104910066
gene id: 9103:LOC104910066
uniprot id: G1MVW5
names: Similarity
messages: Belongs to the peptidase M14 family.

9103:LOC100551205
gene id: 9103:LOC100551205
uniprot id: A0A803YH58
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9103:ADRA1A
gene id: 9103:ADRA1A
uniprot id: G1MWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

9103:LOC100550807
gene id: 9103:LOC100550807
uniprot id: G1N3D8
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

9103:CIAO2A
gene id: 9103:CIAO2A
uniprot id: A0A803Y898
names: Similarity
messages: Belongs to the MIP18 family.

9103:LOC100545512
gene id: 9103:LOC100545512
uniprot id: G1NL98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9103:LOC104911958
gene id: 9103:LOC104911958
uniprot id: G1N722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9103:RRM1
gene id: 9103:RRM1
uniprot id: G1NE68
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

9103:USP20
gene id: 9103:USP20
uniprot id: G1N0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

9103:GLYCTK
gene id: 9103:GLYCTK
uniprot id: G1MWH3
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

9103:SOSTDC1
gene id: 9103:SOSTDC1
uniprot id: G1NCI5
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:POC5
gene id: 9103:POC5
uniprot id: G1N061
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

9103:APAF1
gene id: 9103:APAF1
uniprot id: A0A803YDJ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

9103:LOC104913817
gene id: 9103:LOC104913817
uniprot id: A0A803XUT5
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

9103:LOC100543228
gene id: 9103:LOC100543228
uniprot id: G1MXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

9103:APOD
gene id: 9103:APOD
uniprot id: G1N591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9103:LOC100551379
gene id: 9103:LOC100551379
uniprot id: G1MY81
names: Similarity
messages: Belongs to the lst-2 family.

9103:PIGV
gene id: 9103:PIGV
uniprot id: H9H1L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

9103:SF3B5
gene id: 9103:SF3B5
uniprot id: G1NRR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

9103:GNGT2
gene id: 9103:GNGT2
uniprot id: A0A803XKJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9103:EEF1A2
gene id: 9103:EEF1A2
uniprot id: G3UPD8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9103:CRHBP
gene id: 9103:CRHBP
uniprot id: A0A803YNT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

9103:AP3B2
gene id: 9103:AP3B2
uniprot id: A0A803XMK6
uniprot id: A0A803YEZ2
uniprot id: A0A803YN04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

9103:BBS7
gene id: 9103:BBS7
uniprot id: G3UUI8
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

9103:CCDC181
gene id: 9103:CCDC181
uniprot id: G1NNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

9103:AMOTL2
gene id: 9103:AMOTL2
uniprot id: G1MVB8
names: Similarity
messages: Belongs to the angiomotin family.

9103:LOC100543147
gene id: 9103:LOC100543147
uniprot id: G1N2E8
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:HADHA
gene id: 9103:HADHA
uniprot id: G1NMS8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

9103:WSCD2
gene id: 9103:WSCD2
uniprot id: G3URH6
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

9103:AIMP2
gene id: 9103:AIMP2
uniprot id: G1MRL6
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

9103:DIPK2A
gene id: 9103:DIPK2A
uniprot id: G1N474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9103:SEC11C
gene id: 9103:SEC11C
uniprot id: G1MR20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:STK32A
gene id: 9103:STK32A
uniprot id: A0A803YFF8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:LOC100540504
gene id: 9103:LOC100540504
uniprot id: G1MUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9103:LOC100544563
gene id: 9103:LOC100544563
uniprot id: G1N151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:CDKN1B
gene id: 9103:CDKN1B
uniprot id: G1NM67
names: Similarity
messages: Belongs to the CDI family.

9103:RAF1
gene id: 9103:RAF1
uniprot id: A0A803XNM1
uniprot id: G1N0N1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9103:TADA2A
gene id: 9103:TADA2A
uniprot id: G1N7M1
names: Subcellular Location Annotation
messages: Nucleus

9103:HOMER3
gene id: 9103:HOMER3
uniprot id: G1MZE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9103:NOP58
gene id: 9103:NOP58
uniprot id: G1N828
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9103:NRDC
gene id: 9103:NRDC
uniprot id: G1NF14
names: Similarity
messages: Belongs to the peptidase M16 family.

9103:HACL1
gene id: 9103:HACL1
uniprot id: G1NEC4
names: Similarity
messages: Belongs to the TPP enzyme family.

9103:PSMA1
gene id: 9103:PSMA1
uniprot id: G1N4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Nucleus

9103:MVB12A
gene id: 9103:MVB12A
uniprot id: G1N198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9103:KPNA7
gene id: 9103:KPNA7
uniprot id: G1MY68
names: Similarity
messages: Belongs to the importin alpha family.

9103:C5H11orf49
gene id: 9103:C5H11orf49
uniprot id: A0A803YBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

9103:STOML2
gene id: 9103:STOML2
uniprot id: A0A803XX28
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9103:MEMO1
gene id: 9103:MEMO1
uniprot id: G1NFS7
names: Similarity
messages: Belongs to the MEMO1 family.

9103:TDRD5
gene id: 9103:TDRD5
uniprot id: A0A803Y0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm

9103:HSPB1
gene id: 9103:HSPB1
uniprot id: G1MX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

9103:MRPL32
gene id: 9103:MRPL32
uniprot id: G1NI71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

9103:LOC100544241
gene id: 9103:LOC100544241
uniprot id: G1NES7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:PROX1
gene id: 9103:PROX1
uniprot id: G1NBF1
names: Subcellular Location Annotation
messages: Nucleus

9103:RHCG
gene id: 9103:RHCG
uniprot id: G1N8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9103:SPSB3
gene id: 9103:SPSB3
uniprot id: G1NBT3
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9103:CTPS2
gene id: 9103:CTPS2
uniprot id: G1NPB4
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

9103:BMP7
gene id: 9103:BMP7
uniprot id: A0A803XLM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9103:CASP10
gene id: 9103:CASP10
uniprot id: G1N728
names: Similarity
messages: Belongs to the peptidase C14A family.

9103:SERPINB5
gene id: 9103:SERPINB5
uniprot id: G1MZQ0
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9103:LOC100550173
gene id: 9103:LOC100550173
uniprot id: G5E7R3
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100539035
gene id: 9103:LOC100539035
uniprot id: G1NEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9103:MINDY4
gene id: 9103:MINDY4
uniprot id: A0A803XL46
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9103:LOC100547722
gene id: 9103:LOC100547722
uniprot id: G1NSA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9103:SAMM50
gene id: 9103:SAMM50
uniprot id: G1NM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

9103:MSL3
gene id: 9103:MSL3
uniprot id: G1NPD7
names: Subcellular Location Annotation
messages: Nucleus

9103:STOML3
gene id: 9103:STOML3
uniprot id: G1NQ85
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9103:ACOX2
gene id: 9103:ACOX2
uniprot id: G1N9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

9103:TNFRSF8
gene id: 9103:TNFRSF8
uniprot id: G1N2W0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:YDJC
gene id: 9103:YDJC
uniprot id: G1MQK9
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

9103:PRKAR1A
gene id: 9103:PRKAR1A
uniprot id: G3UQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9103:ZDHHC16
gene id: 9103:ZDHHC16
uniprot id: A0A803XVK1
uniprot id: G1NBV0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:GTF2H1
gene id: 9103:GTF2H1
uniprot id: G1N626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

9103:CHMP4C
gene id: 9103:CHMP4C
uniprot id: G1NGL9
names: Similarity
messages: Belongs to the SNF7 family.

9103:NRXN3
gene id: 9103:NRXN3
uniprot id: A0A803XW36
uniprot id: A0A803YCB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:ETV4
gene id: 9103:ETV4
uniprot id: G1MTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:ELOA
gene id: 9103:ELOA
uniprot id: A0A803YR68
uniprot id: G1N1V8
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC104914226
gene id: 9103:LOC104914226
uniprot id: A0A803YP43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100551374
gene id: 9103:LOC100551374
uniprot id: G1N787
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

9103:NXT2
gene id: 9103:NXT2
uniprot id: A0A803YCA1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9103:TNFRSF6B
gene id: 9103:TNFRSF6B
uniprot id: G1N4U8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:HDAC3
gene id: 9103:HDAC3
uniprot id: G1MT85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

9103:PLK3
gene id: 9103:PLK3
uniprot id: A0A803XXF0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

9103:CFH
gene id: 9103:CFH
uniprot id: A0A803Y7X4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:FLI1
gene id: 9103:FLI1
uniprot id: G1MQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:TMEM200A
gene id: 9103:TMEM200A
uniprot id: G1NRT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

9103:ATP10A
gene id: 9103:ATP10A
uniprot id: G1NPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9103:MYH9
gene id: 9103:MYH9
uniprot id: G1NJB2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:TMEM161B
gene id: 9103:TMEM161B
uniprot id: A0A803Y4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

9103:SLC25A26
gene id: 9103:SLC25A26
uniprot id: G1NAJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:EXTL3
gene id: 9103:EXTL3
uniprot id: G1NN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9103:LYPLA2
gene id: 9103:LYPLA2
uniprot id: G1N1Z7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9103:SCFD1
gene id: 9103:SCFD1
uniprot id: G1NIF4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9103:LOC100549612
gene id: 9103:LOC100549612
uniprot id: G1NRF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

9103:CCNI2
gene id: 9103:CCNI2
uniprot id: G1NA42
names: Similarity
messages: Belongs to the cyclin family.

9103:LOC109363691
gene id: 9103:LOC109363691
uniprot id: G1MUD5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9103:IDH3A
gene id: 9103:IDH3A
uniprot id: A0A803XK05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9103:RTF2
gene id: 9103:RTF2
uniprot id: G1NAA9
names: Similarity
messages: Belongs to the rtf2 family.

9103:PSEN1
gene id: 9103:PSEN1
uniprot id: G1NGN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

9103:LOC100539130
gene id: 9103:LOC100539130
uniprot id: G1NPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

9103:ENTPD3
gene id: 9103:ENTPD3
uniprot id: G1NFL8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9103:TPST2
gene id: 9103:TPST2
uniprot id: G1N4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9103:CD40
gene id: 9103:CD40
uniprot id: A0A803Y327
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:LOC100542070
gene id: 9103:LOC100542070
uniprot id: G1NKI3
names: Similarity
messages: Belongs to the serpin family.

9103:BBOX1
gene id: 9103:BBOX1
uniprot id: G1MSH8
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

9103:DNASE1L3
gene id: 9103:DNASE1L3
uniprot id: G1N4I0
names: Similarity
messages: Belongs to the DNase I family.

9103:CD3E
gene id: 9103:CD3E
uniprot id: G1MXY3
names: Subcellular Location Annotation
messages: Membrane

9103:METTL8
gene id: 9103:METTL8
uniprot id: G1NCP0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9103:AGTR2
gene id: 9103:AGTR2
uniprot id: G1NRP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

9103:PROK1
gene id: 9103:PROK1
uniprot id: A0A803YMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

9103:GPN3
gene id: 9103:GPN3
uniprot id: G1MXD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

9103:ACER2
gene id: 9103:ACER2
uniprot id: A0A803XUJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:CLDN19
gene id: 9103:CLDN19
uniprot id: G1N4W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9103:CYC
gene id: 9103:CYC
uniprot id: P67882
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: The turkey sequence appears to be identical with that of chicken.

9103:CACFD1
gene id: 9103:CACFD1
uniprot id: G1N485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

9103:LOC104913621
gene id: 9103:LOC104913621
uniprot id: B1N1D9
names: Subcellular Location Annotation
messages: Membrane

9103:ADAM17
gene id: 9103:ADAM17
uniprot id: G1NMJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CXCR4
gene id: 9103:CXCR4
uniprot id: G1NRY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

9103:DDC
gene id: 9103:DDC
uniprot id: A0A803Y894
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9103:CCN5
gene id: 9103:CCN5
uniprot id: G1MXL4
names: Similarity
messages: Belongs to the CCN family.

9103:ELF2
gene id: 9103:ELF2
uniprot id: G1MV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:SCNN1A
gene id: 9103:SCNN1A
uniprot id: A0A803YS31
uniprot id: G1NMK0
names: Subcellular Location Annotation
messages: Membrane

9103:S1PR1
gene id: 9103:S1PR1
uniprot id: G3UQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:TBL1XR1
gene id: 9103:TBL1XR1
uniprot id: G1NC30
names: Similarity
messages: Belongs to the WD repeat EBI family.

9103:AKAP1
gene id: 9103:AKAP1
uniprot id: G1N886
names: Subcellular Location Annotation
messages: Cytoplasm

9103:PURG
gene id: 9103:PURG
uniprot id: A0A803YN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

9103:ZPBP
gene id: 9103:ZPBP
uniprot id: G1N3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

9103:LOC100545745
gene id: 9103:LOC100545745
uniprot id: A0A803XSG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

9103:GAPDH
gene id: 9103:GAPDH
uniprot id: C7DR02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
messages: Homotetramer.
messages: cytosol

9103:CNOT2
gene id: 9103:CNOT2
uniprot id: G1NDU7
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

9103:INTS12
gene id: 9103:INTS12
uniprot id: G1N2V8
names: Similarity
messages: Belongs to the Integrator subunit 12 family.

9103:ARSJ
gene id: 9103:ARSJ
uniprot id: G1NEF9
names: Similarity
messages: Belongs to the sulfatase family.

9103:NCLN
gene id: 9103:NCLN
uniprot id: G1MR79
names: Similarity
messages: Belongs to the nicastrin family.

9103:SLC20A2
gene id: 9103:SLC20A2
uniprot id: G3UTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

9103:CLPS
gene id: 9103:CLPS
uniprot id: G1MPW1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

9103:UBE2D3
gene id: 9103:UBE2D3
uniprot id: A0A803YFD6
uniprot id: A0A803YNP5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:PSMD9
gene id: 9103:PSMD9
uniprot id: G1MZ97
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

9103:HEPH
gene id: 9103:HEPH
uniprot id: A0A803XXC4
names: Similarity
messages: Belongs to the multicopper oxidase family.

9103:ADPRH
gene id: 9103:ADPRH
uniprot id: A0A803Y7U0
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9103:FGFR1
gene id: 9103:FGFR1
uniprot id: A0A803YD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

9103:RPS27L
gene id: 9103:RPS27L
uniprot id: A0A803YKZ3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9103:LOC100549117
gene id: 9103:LOC100549117
uniprot id: A0A803XNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9103:LOC100544391
gene id: 9103:LOC100544391
uniprot id: A0A803Y2Z9
names: Similarity
messages: Belongs to the intermediate filament family.

9103:VPS26C
gene id: 9103:VPS26C
uniprot id: G1NNY7
names: Similarity
messages: Belongs to the VPS26 family.

9103:NAP1L4
gene id: 9103:NAP1L4
uniprot id: A0A803XQ49
uniprot id: G1N6Y1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9103:TRIM42
gene id: 9103:TRIM42
uniprot id: G1MZC5
names: Subcellular Location Annotation
messages: Cytoplasm

9103:ABCB11
gene id: 9103:ABCB11
uniprot id: G1NDS9
names: Subcellular Location Annotation
messages: Membrane

9103:PKM
gene id: 9103:PKM
uniprot id: A0A803YCD2
names: Similarity
messages: Belongs to the pyruvate kinase family.

9103:SAMD8
gene id: 9103:SAMD8
uniprot id: G1N2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9103:PCMTD1
gene id: 9103:PCMTD1
uniprot id: A0A803XQD2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9103:TIGD5
gene id: 9103:TIGD5
uniprot id: G1NK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9103:SNX7
gene id: 9103:SNX7
uniprot id: G1N5U1
names: Similarity
messages: Belongs to the sorting nexin family.

9103:ARL6
gene id: 9103:ARL6
uniprot id: G1NNM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

9103:HTR1F
gene id: 9103:HTR1F
uniprot id: G1NS48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

9103:CBL
gene id: 9103:CBL
uniprot id: G1MU46
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

9103:SLC39A13
gene id: 9103:SLC39A13
uniprot id: G1NDY1
names: Subcellular Location Annotation
messages: Membrane

9103:CCDC85C
gene id: 9103:CCDC85C
uniprot id: A0A803XSZ8
uniprot id: G1NKP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

9103:CD38
gene id: 9103:CD38
uniprot id: G1NJ29
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9103:KCNT1
gene id: 9103:KCNT1
uniprot id: G1MWB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:LOC100550755
gene id: 9103:LOC100550755
uniprot id: A0A803YMN3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:SPARCL1
gene id: 9103:SPARCL1
uniprot id: G1N6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

9103:WAPL
gene id: 9103:WAPL
uniprot id: A0A803XUQ9
uniprot id: G1MUI9
names: Similarity
messages: Belongs to the WAPL family.

9103:DYNLL2
gene id: 9103:DYNLL2
uniprot id: A0A803XMB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9103:LOC100542838
gene id: 9103:LOC100542838
uniprot id: G1NFH4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

9103:LOC100541147
gene id: 9103:LOC100541147
uniprot id: G1NCP6
names: Similarity
messages: Belongs to the actin family.

9103:RPL35A
gene id: 9103:RPL35A
uniprot id: G1N7Q5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

9103:TUBB1
gene id: 9103:TUBB1
uniprot id: G1N9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9103:UNC93B1
gene id: 9103:UNC93B1
uniprot id: G1MXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9103:AGAP1
gene id: 9103:AGAP1
uniprot id: A0A803XT71
uniprot id: A0A803YK39
uniprot id: A0A803YQX3
names: Similarity
messages: Belongs to the centaurin gamma-like family.

9103:CTU2
gene id: 9103:CTU2
uniprot id: G1N706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

9103:GEM
gene id: 9103:GEM
uniprot id: G1NHG3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9103:UBE2E1
gene id: 9103:UBE2E1
uniprot id: G1NET4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:HOGA1
gene id: 9103:HOGA1
uniprot id: G1NBP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

9103:C11H18orf32
gene id: 9103:C11H18orf32
uniprot id: G1MRG6
names: Similarity
messages: Belongs to the UPF0729 family.

9103:SNRPD3
gene id: 9103:SNRPD3
uniprot id: G1NR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

9103:GUCY1A1
gene id: 9103:GUCY1A1
uniprot id: G1MRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9103:PIWIL1
gene id: 9103:PIWIL1
uniprot id: A0A803Y0D8
names: Similarity
messages: Belongs to the argonaute family.

9103:LOC100541213
gene id: 9103:LOC100541213
uniprot id: G1MSP7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9103:UBE4A
gene id: 9103:UBE4A
uniprot id: G1MV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

9103:KAT6A
gene id: 9103:KAT6A
uniprot id: G1MW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9103:LTN1
gene id: 9103:LTN1
uniprot id: G1NNU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

9103:LOC100539085
gene id: 9103:LOC100539085
uniprot id: G1NMY4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:ATP6V1D
gene id: 9103:ATP6V1D
uniprot id: G1NHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

9103:FOXJ2
gene id: 9103:FOXJ2
uniprot id: G1NMD7
names: Subcellular Location Annotation
messages: Nucleus

9103:WNT5B
gene id: 9103:WNT5B
uniprot id: G1NL28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9103:GSTA3
gene id: 9103:GSTA3
uniprot id: D4N2R6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9103:GRB2
gene id: 9103:GRB2
uniprot id: G1NB29
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

9103:COX1
gene id: 9103:COX1
uniprot id: A9XBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9103:FGG
gene id: 9103:FGG
uniprot id: G1MRP5
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9103:VEGFD
gene id: 9103:VEGFD
uniprot id: G1NPC2
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9103:TDRD9
gene id: 9103:TDRD9
uniprot id: A0A803XNL6
uniprot id: G1NL37
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

9103:STARD3NL
gene id: 9103:STARD3NL
uniprot id: G1NHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

9103:GTF2B
gene id: 9103:GTF2B
uniprot id: A0A803Y749
names: Similarity
messages: Belongs to the TFIIB family.

9103:LOC100540211
gene id: 9103:LOC100540211
uniprot id: G1NQ81
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

9103:LOC100550621
gene id: 9103:LOC100550621
uniprot id: G1N6H7
names: Similarity
messages: Belongs to the DDI1 family.

9103:IMPA2
gene id: 9103:IMPA2
uniprot id: G1N9L6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9103:EDNRA
gene id: 9103:EDNRA
uniprot id: G1MXS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

9103:TAAR2
gene id: 9103:TAAR2
uniprot id: G1NRS9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:LOC100545797
gene id: 9103:LOC100545797
uniprot id: G1NFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: Required for assembly of mitochondrial respiratory chain complexes.

9103:MRE11
gene id: 9103:MRE11
uniprot id: G3UUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

9103:LOC104912467
gene id: 9103:LOC104912467
uniprot id: G1NM66
names: Similarity
messages: Belongs to the CDI family.

9103:TMEM242
gene id: 9103:TMEM242
uniprot id: G1NJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

9103:ARHGEF6
gene id: 9103:ARHGEF6
uniprot id: G1MXE9
names: Subcellular Location Annotation
messages: lamellipodium

9103:TIPRL
gene id: 9103:TIPRL
uniprot id: G1NNG2
names: Similarity
messages: Belongs to the TIP41 family.

9103:TNFSF15
gene id: 9103:TNFSF15
uniprot id: A0A803Y4W8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9103:TSHZ2
gene id: 9103:TSHZ2
uniprot id: G1NRB1
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

9103:KRT23
gene id: 9103:KRT23
uniprot id: G1MVN7
names: Similarity
messages: Belongs to the intermediate filament family.

9103:LOC100538504
gene id: 9103:LOC100538504
uniprot id: H9H0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9103:SLC35F1
gene id: 9103:SLC35F1
uniprot id: G1NKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9103:LOC100549019
gene id: 9103:LOC100549019
uniprot id: A0A803YK26
names: Subcellular Location Annotation
messages: cytoskeleton

9103:LOC100549829
gene id: 9103:LOC100549829
uniprot id: G1NHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

9103:TACSTD2
gene id: 9103:TACSTD2
uniprot id: G1NR03
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:DCTN4
gene id: 9103:DCTN4
uniprot id: G1N3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

9103:VIPR2
gene id: 9103:VIPR2
uniprot id: G1N143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9103:MAPK1IP1L
gene id: 9103:MAPK1IP1L
uniprot id: G1NLP2
names: Similarity
messages: Belongs to the MISS family.

9103:CLCN2
gene id: 9103:CLCN2
uniprot id: G5E7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

9103:INTS11
gene id: 9103:INTS11
uniprot id: A0A803Y209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

9103:PRKAA1
gene id: 9103:PRKAA1
uniprot id: A3RLM9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9103:ESCO2
gene id: 9103:ESCO2
uniprot id: A0A803YJI3
uniprot id: G1NMV2
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC104914649
gene id: 9103:LOC104914649
uniprot id: A0A803XZL6
uniprot id: G1MRR8
names: Similarity
messages: Belongs to the HARBI1 family.

9103:ARMC9
gene id: 9103:ARMC9
uniprot id: A0A803YQ00
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

9103:LOC100550056
gene id: 9103:LOC100550056
uniprot id: G1MTF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9103:LOC100548689
gene id: 9103:LOC100548689
uniprot id: G1NIH0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9103:COMT
gene id: 9103:COMT
uniprot id: G1MRP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.

9103:SLC5A3
gene id: 9103:SLC5A3
uniprot id: G1NS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9103:TMEM50B
gene id: 9103:TMEM50B
uniprot id: G1NNX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

9103:ANXA4
gene id: 9103:ANXA4
uniprot id: H9H0B3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

9103:GPR20
gene id: 9103:GPR20
uniprot id: G1NRT8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:DPT
gene id: 9103:DPT
uniprot id: G1NNG0
names: Similarity
messages: Belongs to the dermatopontin family.

9103:RPS6KA6
gene id: 9103:RPS6KA6
uniprot id: G1MZX0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9103:GPR146
gene id: 9103:GPR146
uniprot id: G1MTG9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:LOC104913232
gene id: 9103:LOC104913232
uniprot id: G3UP54
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:LOC100549030
gene id: 9103:LOC100549030
uniprot id: A0A803XTY0
names: Subcellular Location Annotation
messages: Membrane

9103:ADCK1
gene id: 9103:ADCK1
uniprot id: G1NJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

9103:NMNAT1
gene id: 9103:NMNAT1
uniprot id: G1MY88
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9103:NT5DC2
gene id: 9103:NT5DC2
uniprot id: G1MQG2
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9103:FECH
gene id: 9103:FECH
uniprot id: A0A803XUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

9103:LOC100547732
gene id: 9103:LOC100547732
uniprot id: G1N5H4
names: Similarity
messages: Belongs to the GroES chaperonin family.

9103:PER3
gene id: 9103:PER3
uniprot id: G1MQN1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:NDUFA8
gene id: 9103:NDUFA8
uniprot id: G3UQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9103:PTN
gene id: 9103:PTN
uniprot id: G1NKP6
names: Similarity
messages: Belongs to the pleiotrophin family.

9103:MED13L
gene id: 9103:MED13L
uniprot id: G1NCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9103:LOC100548208
gene id: 9103:LOC100548208
uniprot id: G1MXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:SLCO3A1
gene id: 9103:SLCO3A1
uniprot id: G1N9S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

9103:SGK1
gene id: 9103:SGK1
uniprot id: G1NKB1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:NFYA
gene id: 9103:NFYA
uniprot id: G1NCN2
uniprot id: G3X8L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

9103:GRPR
gene id: 9103:GRPR
uniprot id: G1NPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:MEGF6
gene id: 9103:MEGF6
uniprot id: G1MSK3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:EPGN
gene id: 9103:EPGN
uniprot id: G1N5I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:SEC23B
gene id: 9103:SEC23B
uniprot id: G1N4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9103:KLC4
gene id: 9103:KLC4
uniprot id: G1MXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9103:CHD4
gene id: 9103:CHD4
uniprot id: G1NMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9103:VTA1
gene id: 9103:VTA1
uniprot id: G1NJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

9103:COX3
gene id: 9103:COX3
uniprot id: F1JUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

9103:MUC2
gene id: 9103:MUC2
uniprot id: G1N988
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100539364
gene id: 9103:LOC100539364
uniprot id: G1NHF5
names: Similarity
messages: Belongs to the AccD/PCCB family.

9103:SNAP25
gene id: 9103:SNAP25
uniprot id: G1N3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

9103:GFOD2
gene id: 9103:GFOD2
uniprot id: A0A803YK88
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

9103:HS6ST2
gene id: 9103:HS6ST2
uniprot id: G1MVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

9103:LOC104911571
gene id: 9103:LOC104911571
uniprot id: G1NKB0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:CETP
gene id: 9103:CETP
uniprot id: G1MVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

9103:LHFPL2
gene id: 9103:LHFPL2
uniprot id: G1MZQ8
names: Subcellular Location Annotation
messages: Membrane

9103:LAPTM5
gene id: 9103:LAPTM5
uniprot id: G1MPW9
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9103:AADAC
gene id: 9103:AADAC
uniprot id: G1NEI5
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9103:TFB1M
gene id: 9103:TFB1M
uniprot id: G1NJG6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

9103:PDCL
gene id: 9103:PDCL
uniprot id: G1N7F4
names: Similarity
messages: Belongs to the phosducin family.

9103:ATP6V1H
gene id: 9103:ATP6V1H
uniprot id: A0A803XZD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9103:IDS
gene id: 9103:IDS
uniprot id: G1N835
names: Similarity
messages: Belongs to the sulfatase family.

9103:C23H1orf158
gene id: 9103:C23H1orf158
uniprot id: G1N2J2
names: Function
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.

9103:CSNK2A1
gene id: 9103:CSNK2A1
uniprot id: G1N6J4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:PNMT
gene id: 9103:PNMT
uniprot id: A0A803YQ71
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9103:STON2
gene id: 9103:STON2
uniprot id: G3UP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

9103:VWC2L
gene id: 9103:VWC2L
uniprot id: A0A803Y548
uniprot id: G1MX43
names: Subcellular Location Annotation
messages: Synapse

9103:SPPL2B
gene id: 9103:SPPL2B
uniprot id: G1MQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

9103:LOC104911898
gene id: 9103:LOC104911898
uniprot id: G1MUS7
names: Similarity
messages: Belongs to the CCSER family.

9103:LOC104909450
gene id: 9103:LOC104909450
uniprot id: A0A803YPC9
names: Subcellular Location Annotation
messages: Nucleus

9103:LSM8
gene id: 9103:LSM8
uniprot id: G1N9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9103:LOC100548843
gene id: 9103:LOC100548843
uniprot id: G1NIJ9
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9103:RAPGEF2
gene id: 9103:RAPGEF2
uniprot id: A0A803XTB7
uniprot id: G1MTB7
names: Similarity
messages: Belongs to the RAPGEF2 family.

9103:LOC104914778
gene id: 9103:LOC104914778
uniprot id: A0A803YRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9103:ROPN1L
gene id: 9103:ROPN1L
uniprot id: G1N2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

9103:LYRM1
gene id: 9103:LYRM1
uniprot id: G1ND83
names: Similarity
messages: Belongs to the complex I LYR family.

9103:SURF4
gene id: 9103:SURF4
uniprot id: G3UQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:TRIM2
gene id: 9103:TRIM2
uniprot id: G1MR29
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9103:LOC100546986
gene id: 9103:LOC100546986
uniprot id: G1MWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9103:FAM3D
gene id: 9103:FAM3D
uniprot id: G1N9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9103:LOC100542665
gene id: 9103:LOC100542665
uniprot id: A0A803YMB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:RPL6
gene id: 9103:RPL6
uniprot id: G1N231
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

9103:IFT20
gene id: 9103:IFT20
uniprot id: G1N8U6
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

9103:SESN3
gene id: 9103:SESN3
uniprot id: G1NQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9103:LOC100542475
gene id: 9103:LOC100542475
uniprot id: G1NFU9
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9103:LOC100549160
gene id: 9103:LOC100549160
uniprot id: G1NFZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:ECRG4
gene id: 9103:ECRG4
uniprot id: G1NPP2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

9103:NIPAL2
gene id: 9103:NIPAL2
uniprot id: G1NHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9103:SIGMAR1
gene id: 9103:SIGMAR1
uniprot id: A0A803YPL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

9103:SSR1
gene id: 9103:SSR1
uniprot id: G1MXQ0
uniprot id: G5E7N7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

9103:THG1L
gene id: 9103:THG1L
uniprot id: G1N0C5
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

9103:TRAK1
gene id: 9103:TRAK1
uniprot id: G1NGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

9103:MAP3K8
gene id: 9103:MAP3K8
uniprot id: G1N440
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9103:C8H10orf90
gene id: 9103:C8H10orf90
uniprot id: G1NGT1
names: Subcellular Location Annotation
messages: centrosome

9103:TPM4
gene id: 9103:TPM4
uniprot id: G3USL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9103:JAKMIP2
gene id: 9103:JAKMIP2
uniprot id: A0A803Y421
uniprot id: G1NBI7
names: Similarity
messages: Belongs to the JAKMIP family.

9103:RAD21
gene id: 9103:RAD21
uniprot id: G3URP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9103:TBX15
gene id: 9103:TBX15
uniprot id: G1NN54
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9103:OSBPL2
gene id: 9103:OSBPL2
uniprot id: G1N1K6
names: Similarity
messages: Belongs to the OSBP family.

9103:LOC723981
gene id: 9103:LOC723981
uniprot id: Q71SZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

9103:GGA3
gene id: 9103:GGA3
uniprot id: A0A803XS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9103:CASKIN2
gene id: 9103:CASKIN2
uniprot id: A0A803XKY5
uniprot id: A0A803XZX1
names: Subcellular Location Annotation
messages: Cytoplasm

9103:ALDH9A1
gene id: 9103:ALDH9A1
uniprot id: G1MWU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9103:LITAF
gene id: 9103:LITAF
uniprot id: G1MR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

9103:LOC100551000
gene id: 9103:LOC100551000
uniprot id: G1NGC4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9103:HNRNPK
gene id: 9103:HNRNPK
uniprot id: G1N3K4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

9103:LOC100543851
gene id: 9103:LOC100543851
uniprot id: G3UV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9103:CNRIP1
gene id: 9103:CNRIP1
uniprot id: G1MZ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

9103:LRRC42
gene id: 9103:LRRC42
uniprot id: G1NFP5
names: Similarity
messages: Belongs to the LRRC42 family.

9103:DHFR
gene id: 9103:DHFR
uniprot id: H9H0F8
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

9103:F2R
gene id: 9103:F2R
uniprot id: A0A803Y891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:DOHH
gene id: 9103:DOHH
uniprot id: G1MRT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

9103:YJU2
gene id: 9103:YJU2
uniprot id: H9H1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

9103:STAR
gene id: 9103:STAR
uniprot id: G1MTF0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

9103:STK40
gene id: 9103:STK40
uniprot id: G1MX03
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

9103:RNASEH1
gene id: 9103:RNASEH1
uniprot id: G1NMH5
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

9103:IL17REL
gene id: 9103:IL17REL
uniprot id: G1N753
names: Subcellular Location Annotation
messages: Cell membrane

9103:SH3GL3
gene id: 9103:SH3GL3
uniprot id: G3UPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

9103:AKR1D1
gene id: 9103:AKR1D1
uniprot id: G1NKF1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9103:MTMR1
gene id: 9103:MTMR1
uniprot id: A0A803XYR2
uniprot id: A0A803Y0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9103:LOC100547437
gene id: 9103:LOC100547437
uniprot id: G1N2B2
names: Similarity
messages: Belongs to the threonine aldolase family.

9103:FAM72A
gene id: 9103:FAM72A
uniprot id: G1MWK5
names: Similarity
messages: Belongs to the FAM72 family.

9103:IL7R
gene id: 9103:IL7R
uniprot id: G1N9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
messages: The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

9103:IL10
gene id: 9103:IL10
uniprot id: A2VBZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9103:PSMB1
gene id: 9103:PSMB1
uniprot id: G1NHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9103:LOC100541378
gene id: 9103:LOC100541378
uniprot id: G1NAK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:JAGN1
gene id: 9103:JAGN1
uniprot id: G1N8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:HTR1D
gene id: 9103:HTR1D
uniprot id: G1NRI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:PANX3
gene id: 9103:PANX3
uniprot id: A0A803Y857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9103:ATP1B1
gene id: 9103:ATP1B1
uniprot id: G1NNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9103:LOC100545322
gene id: 9103:LOC100545322
uniprot id: G1NF62
names: Similarity
messages: Belongs to the intermediate filament family.

9103:RPA2
gene id: 9103:RPA2
uniprot id: G1MQZ0
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

9103:HDHD2
gene id: 9103:HDHD2
uniprot id: G1MZW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9103:HEATR5A
gene id: 9103:HEATR5A
uniprot id: A0A803XUH6
uniprot id: G1NIJ2
names: Similarity
messages: Belongs to the HEATR5 family.

9103:KCNC4
gene id: 9103:KCNC4
uniprot id: A0A803Y3V5
uniprot id: G1MSJ0
names: Subcellular Location Annotation
messages: Membrane

9103:SMAD1
gene id: 9103:SMAD1
uniprot id: G1MXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9103:TECPR1
gene id: 9103:TECPR1
uniprot id: G1MS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

9103:LOC100550464
gene id: 9103:LOC100550464
uniprot id: G1MX38
names: Similarity
messages: Belongs to the fructosamine kinase family.

9103:YTHDC1
gene id: 9103:YTHDC1
uniprot id: G3UNX8
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9103:LOC104914598
gene id: 9103:LOC104914598
uniprot id: H9H0H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

9103:LOXL3
gene id: 9103:LOXL3
uniprot id: A0A803XN89
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9103:ALKAL2
gene id: 9103:ALKAL2
uniprot id: G1NMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

9103:TOP1MT
gene id: 9103:TOP1MT
uniprot id: G1MVV7
uniprot id: G1NK05
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

9103:MRPL30
gene id: 9103:MRPL30
uniprot id: A0A803YJX3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9103:OPRM1
gene id: 9103:OPRM1
uniprot id: G1NJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

9103:UNG
gene id: 9103:UNG
uniprot id: G1N2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

9103:MCTP2
gene id: 9103:MCTP2
uniprot id: G1NA76
names: Subcellular Location Annotation
messages: Membrane

9103:SHMT1
gene id: 9103:SHMT1
uniprot id: G1N0B8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

9103:ASIP
gene id: 9103:ASIP
uniprot id: G1MTH0
names: Subcellular Location Annotation
messages: Secreted

9103:EMC6
gene id: 9103:EMC6
uniprot id: A0A803XQ42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC104914617
gene id: 9103:LOC104914617
uniprot id: A0A803YHG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:PIGF
gene id: 9103:PIGF
uniprot id: G1ND46
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:ETS2
gene id: 9103:ETS2
uniprot id: G1NNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

9103:EPC2
gene id: 9103:EPC2
uniprot id: G1NJ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

9103:STAC
gene id: 9103:STAC
uniprot id: A0A803XS17
names: Subcellular Location Annotation
messages: sarcolemma

9103:GRPEL1
gene id: 9103:GRPEL1
uniprot id: G1NJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

9103:LOC100541308
gene id: 9103:LOC100541308
uniprot id: A0A803XPL7
uniprot id: A0A803Y8L6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:PDE6G
gene id: 9103:PDE6G
uniprot id: G1N3U3
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

9103:BCL2A1
gene id: 9103:BCL2A1
uniprot id: G1N8C5
names: Similarity
messages: Belongs to the Bcl-2 family.

9103:SDR16C5
gene id: 9103:SDR16C5
uniprot id: G1NEV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:PTDSS1
gene id: 9103:PTDSS1
uniprot id: G1NHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:GSDME
gene id: 9103:GSDME
uniprot id: G3UR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9103:CLDN8
gene id: 9103:CLDN8
uniprot id: G1NS63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9103:GSC
gene id: 9103:GSC
uniprot id: G1NKI7
names: Subcellular Location Annotation
messages: Nucleus

9103:BMP4
gene id: 9103:BMP4
uniprot id: A0A803Y9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9103:LOC100543474
gene id: 9103:LOC100543474
uniprot id: G1NDX0
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9103:LOC104913658
gene id: 9103:LOC104913658
uniprot id: G1MTP8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9103:ADAM23
gene id: 9103:ADAM23
uniprot id: A0A803Y2J3
uniprot id: G1N8Q6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CLSTN3
gene id: 9103:CLSTN3
uniprot id: G1NMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

9103:BTD
gene id: 9103:BTD
uniprot id: G1NED4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9103:LOC104912200
gene id: 9103:LOC104912200
uniprot id: G1NM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9103:ABHD2
gene id: 9103:ABHD2
uniprot id: G1N922
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9103:TCEA1
gene id: 9103:TCEA1
uniprot id: G1NEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

9103:SMARCAD1
gene id: 9103:SMARCAD1
uniprot id: G1N1U1
names: Subcellular Location Annotation
messages: Chromosome

9103:DBX1
gene id: 9103:DBX1
uniprot id: G1MTT0
names: Subcellular Location Annotation
messages: Nucleus

9103:NTRK3
gene id: 9103:NTRK3
uniprot id: G1N9F1
uniprot id: G3UQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9103:KCNE2
gene id: 9103:KCNE2
uniprot id: G1NS86
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9103:LOC100549006
gene id: 9103:LOC100549006
uniprot id: A0A803YD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:COQ8A
gene id: 9103:COQ8A
uniprot id: G1N2M4
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

9103:ABI2
gene id: 9103:ABI2
uniprot id: A0A803XNB6
uniprot id: A0A803YBC7
uniprot id: G1N9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

9103:LOC100550554
gene id: 9103:LOC100550554
uniprot id: A0A803YQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9103:KCNH6
gene id: 9103:KCNH6
uniprot id: G3UTD8
names: Subcellular Location Annotation
messages: Membrane

9103:DRAM1
gene id: 9103:DRAM1
uniprot id: A0A803XXI9
uniprot id: G1NK76
names: Subcellular Location Annotation
messages: Membrane

9103:RPL7L1
gene id: 9103:RPL7L1
uniprot id: G1NE29
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9103:LOC100550995
gene id: 9103:LOC100550995
uniprot id: A0A803XKS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:MTMR8
gene id: 9103:MTMR8
uniprot id: G3UQ85
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9103:OGFR
gene id: 9103:OGFR
uniprot id: A0A803Y6A5
uniprot id: G1N2F7
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

9103:LOC100539535
gene id: 9103:LOC100539535
uniprot id: G1MQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9103:ENO1
gene id: 9103:ENO1
uniprot id: A0A803YQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9103:RHO
gene id: 9103:RHO
uniprot id: G1ND14
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

9103:RSPO4
gene id: 9103:RSPO4
uniprot id: G1N7G8
names: Similarity
messages: Belongs to the R-spondin family.

9103:LOC100549955
gene id: 9103:LOC100549955
uniprot id: G1MV65
names: Similarity
messages: Belongs to the perilipin family.

9103:TP73
gene id: 9103:TP73
uniprot id: G1MS29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Nucleus
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

9103:LOC100542243
gene id: 9103:LOC100542243
uniprot id: A0A803YD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9103:TWF1
gene id: 9103:TWF1
uniprot id: G1NB75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

9103:TRAF1
gene id: 9103:TRAF1
uniprot id: A0A803YRV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9103:HSPB7
gene id: 9103:HSPB7
uniprot id: G1N0N8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9103:KXD1
gene id: 9103:KXD1
uniprot id: A0A803Y5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

9103:ALG11
gene id: 9103:ALG11
uniprot id: G1NQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

9103:KCTD20
gene id: 9103:KCTD20
uniprot id: A0A803XWE4
uniprot id: A0A803Y5B0
uniprot id: G1MU82
names: Subcellular Location Annotation
messages: Cytoplasm

9103:NBN
gene id: 9103:NBN
uniprot id: A0A803XZX2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

9103:RFC2
gene id: 9103:RFC2
uniprot id: G1MUA0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

9103:C8B
gene id: 9103:C8B
uniprot id: G1NG42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:ACKR3
gene id: 9103:ACKR3
uniprot id: G1NS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:RPS14
gene id: 9103:RPS14
uniprot id: G1N479
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

9103:HDC
gene id: 9103:HDC
uniprot id: A0A803YD44
uniprot id: G1N6G5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9103:C1H12orf57
gene id: 9103:C1H12orf57
uniprot id: G1NMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

9103:RNF111
gene id: 9103:RNF111
uniprot id: G1N144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

9103:SPON2
gene id: 9103:SPON2
uniprot id: G1NK95
names: Subcellular Location Annotation
messages: extracellular matrix

9103:VWA3A
gene id: 9103:VWA3A
uniprot id: A0A803XM96
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9103:FUNDC1
gene id: 9103:FUNDC1
uniprot id: G1NP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

9103:LOC100541042
gene id: 9103:LOC100541042
uniprot id: G1NF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9103:TAF8
gene id: 9103:TAF8
uniprot id: G1N3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

9103:CLRN2
gene id: 9103:CLRN2
uniprot id: G1NIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9103:LOC100545577
gene id: 9103:LOC100545577
uniprot id: G1NGK0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9103:EXTL2
gene id: 9103:EXTL2
uniprot id: G1N4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9103:ZDHHC5
gene id: 9103:ZDHHC5
uniprot id: G1NBH9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:CETN2
gene id: 9103:CETN2
uniprot id: G1N1G4
names: Similarity
messages: Belongs to the centrin family.

9103:LSM1
gene id: 9103:LSM1
uniprot id: G1MTD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

9103:ALG12
gene id: 9103:ALG12
uniprot id: G1N731
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:ACTR3
gene id: 9103:ACTR3
uniprot id: G1NIH4
names: Similarity
messages: Belongs to the actin family.

9103:SLC23A1
gene id: 9103:SLC23A1
uniprot id: G1MRD2
names: Subcellular Location Annotation
messages: Membrane

9103:UCK1
gene id: 9103:UCK1
uniprot id: G1N2D0
names: Similarity
messages: Belongs to the uridine kinase family.

9103:LOC104913587
gene id: 9103:LOC104913587
uniprot id: A0A803XLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9103:RAD51
gene id: 9103:RAD51
uniprot id: G5E7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

9103:RPL30
gene id: 9103:RPL30
uniprot id: G1NHU3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

9103:DAD1
gene id: 9103:DAD1
uniprot id: G1MPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9103:CCNK
gene id: 9103:CCNK
uniprot id: G1NJG3
names: Similarity
messages: Belongs to the cyclin family.

9103:DUSP5
gene id: 9103:DUSP5
uniprot id: G1NEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

9103:LOC100542183
gene id: 9103:LOC100542183
uniprot id: G3UR00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:ACOT13
gene id: 9103:ACOT13
uniprot id: G1N7H6
names: Similarity
messages: Belongs to the thioesterase PaaI family.

9103:LANCL2
gene id: 9103:LANCL2
uniprot id: A0A803Y6W9
names: Similarity
messages: Belongs to the LanC-like protein family.

9103:HSPB9
gene id: 9103:HSPB9
uniprot id: A0A803YQM6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9103:NSUN4
gene id: 9103:NSUN4
uniprot id: G1NDY0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9103:C8A
gene id: 9103:C8A
uniprot id: G1NG31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:DRD2
gene id: 9103:DRD2
uniprot id: G1MYK5
uniprot id: O73810
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity). Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
messages: Forms homo- and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with CADPS and CADPS2 (By similarity). Interacts with GPRASP1, PPP1R9B and CLIC6. Interacts with ARRB2 (By similarity). Interacts with HTR2A (By similarity). Interacts with DRD1. Interacts with KCNA2 (By similarity).
messages: Golgi apparatus membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.

9103:PCBP4
gene id: 9103:PCBP4
uniprot id: G1MXR3
names: Subcellular Location Annotation
messages: Cytoplasm

9103:HIF1A
gene id: 9103:HIF1A
uniprot id: A0A803XM52
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:PPRC1
gene id: 9103:PPRC1
uniprot id: G1NCC7
names: Subcellular Location Annotation
messages: Nucleus

9103:MTFR2
gene id: 9103:MTFR2
uniprot id: G1NK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9103:ABCC1
gene id: 9103:ABCC1
uniprot id: A0A803YQX9
uniprot id: A0A803YRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9103:MFSD1
gene id: 9103:MFSD1
uniprot id: G1NDU0
names: Subcellular Location Annotation
messages: Membrane

9103:CRYBB2
gene id: 9103:CRYBB2
uniprot id: G3URF3
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9103:NELFCD
gene id: 9103:NELFCD
uniprot id: G3URE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

9103:LOC104909393
gene id: 9103:LOC104909393
uniprot id: G1NQT2
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9103:DUS3L
gene id: 9103:DUS3L
uniprot id: G1MS01
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

9103:TCN2
gene id: 9103:TCN2
uniprot id: G1NNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9103:LOC116216167
gene id: 9103:LOC116216167
uniprot id: A0A803YPB9
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9103:PLAGL1
gene id: 9103:PLAGL1
uniprot id: A0A803Y2T5
names: Subcellular Location Annotation
messages: Nucleus

9103:SSR3
gene id: 9103:SSR3
uniprot id: G1NE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9103:PSME4
gene id: 9103:PSME4
uniprot id: G1MUG7
names: Similarity
messages: Belongs to the BLM10 family.

9103:BRPF1
gene id: 9103:BRPF1
uniprot id: G1N8B5
names: Subcellular Location Annotation
messages: Nucleus

9103:VCP
gene id: 9103:VCP
uniprot id: G1MUF5
names: Similarity
messages: Belongs to the AAA ATPase family.

9103:CREBL2
gene id: 9103:CREBL2
uniprot id: G1NKP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

9103:SLC17A8
gene id: 9103:SLC17A8
uniprot id: G1NGM1
names: Subcellular Location Annotation
messages: Membrane

9103:MGME1
gene id: 9103:MGME1
uniprot id: G1N4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.
messages: Mitochondrion

9103:YPEL1
gene id: 9103:YPEL1
uniprot id: G1MQU3
names: Similarity
messages: Belongs to the yippee family.

9103:NOL12
gene id: 9103:NOL12
uniprot id: G1NIU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

9103:CSNK1G2
gene id: 9103:CSNK1G2
uniprot id: G1MTK4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:NDST1
gene id: 9103:NDST1
uniprot id: G1N466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9103:NDOR1
gene id: 9103:NDOR1
uniprot id: A0A803XST0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

9103:MB
gene id: 9103:MB
uniprot id: G1NJB6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

9103:PDE1A
gene id: 9103:PDE1A
uniprot id: A0A803XSN6
uniprot id: A0A803YDQ1
uniprot id: G1NA27
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:RNFT2
gene id: 9103:RNFT2
uniprot id: G1NCA9
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100542248
gene id: 9103:LOC100542248
uniprot id: G1N0J9
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9103:ADRA1B
gene id: 9103:ADRA1B
uniprot id: G1MVG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

9103:NDST2
gene id: 9103:NDST2
uniprot id: G1N3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9103:BCL2L14
gene id: 9103:BCL2L14
uniprot id: G3UPV4
names: Similarity
messages: Belongs to the Bcl-2 family.

9103:LOC100551192
gene id: 9103:LOC100551192
uniprot id: G1NND9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9103:A4GNT
gene id: 9103:A4GNT
uniprot id: G1MUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

9103:CASP2
gene id: 9103:CASP2
uniprot id: G1MZ40
names: Similarity
messages: Belongs to the peptidase C14A family.

9103:BYSL
gene id: 9103:BYSL
uniprot id: A0A803XXY3
names: Similarity
messages: Belongs to the bystin family.

9103:NT5C3B
gene id: 9103:NT5C3B
uniprot id: G1N599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

9103:MAN2C1
gene id: 9103:MAN2C1
uniprot id: G1MVW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

9103:FRG1
gene id: 9103:FRG1
uniprot id: A0A803YA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

9103:EFTUD2
gene id: 9103:EFTUD2
uniprot id: G1NCI7
names: Subcellular Location Annotation
messages: Nucleus

9103:EXOC7
gene id: 9103:EXOC7
uniprot id: G1MYP9
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

9103:CHRD
gene id: 9103:CHRD
uniprot id: G1NBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Secreted

9103:BLM
gene id: 9103:BLM
uniprot id: H9H1R8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

9103:LOC100542253
gene id: 9103:LOC100542253
uniprot id: G3UQA8
names: Similarity
messages: Belongs to the intermediate filament family.

9103:RPL29
gene id: 9103:RPL29
uniprot id: A0A803Y7F6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

9103:LOC100548822
gene id: 9103:LOC100548822
uniprot id: G1MYC2
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

9103:LOC100550477
gene id: 9103:LOC100550477
uniprot id: G1N6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

9103:HAO2
gene id: 9103:HAO2
uniprot id: G1NN50
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

9103:TMEM168
gene id: 9103:TMEM168
uniprot id: G1NA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

9103:SMCO4
gene id: 9103:SMCO4
uniprot id: A0A803Y664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMCO4 family.
messages: Membrane

9103:UTS2
gene id: 9103:UTS2
uniprot id: G1MQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

9103:LOC100550479
gene id: 9103:LOC100550479
uniprot id: A0A803Y3M4
names: Subcellular Location Annotation
messages: Membrane

9103:MRPL27
gene id: 9103:MRPL27
uniprot id: G1NA99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

9103:C3H5orf22
gene id: 9103:C3H5orf22
uniprot id: G1N0J7
names: Similarity
messages: Belongs to the UPF0489 family.

9103:IL18RAP
gene id: 9103:IL18RAP
uniprot id: G1NPN2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9103:MFN2
gene id: 9103:MFN2
uniprot id: G1N301
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9103:ASCC1
gene id: 9103:ASCC1
uniprot id: G1N1E0
names: Subcellular Location Annotation
messages: Cytoplasm

9103:TMED6
gene id: 9103:TMED6
uniprot id: G1N8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:SLC6A9
gene id: 9103:SLC6A9
uniprot id: G1NCD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

9103:LPCAT1
gene id: 9103:LPCAT1
uniprot id: G1N5M4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9103:WNT7B
gene id: 9103:WNT7B
uniprot id: G1NM45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9103:DLD
gene id: 9103:DLD
uniprot id: G1NC58
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

9103:DUSP16
gene id: 9103:DUSP16
uniprot id: G1NM65
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9103:CHPF
gene id: 9103:CHPF
uniprot id: G1NFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9103:FGFBP2
gene id: 9103:FGFBP2
uniprot id: G1NJ27
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

9103:TCTN2
gene id: 9103:TCTN2
uniprot id: G1MVR2
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

9103:GDF1
gene id: 9103:GDF1
uniprot id: G1MZR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9103:CORO2A
gene id: 9103:CORO2A
uniprot id: A0A803XY34
names: Similarity
messages: Belongs to the WD repeat coronin family.

9103:ATP6V1A
gene id: 9103:ATP6V1A
uniprot id: G1NN61
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

9103:CCR7
gene id: 9103:CCR7
uniprot id: G1MV68
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:ATP6
gene id: 9103:ATP6
uniprot id: A9XBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

9103:ABRAXAS1
gene id: 9103:ABRAXAS1
uniprot id: G1N7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Nucleus

9103:TUBGCP4
gene id: 9103:TUBGCP4
uniprot id: G1NE90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9103:LOC100538829
gene id: 9103:LOC100538829
uniprot id: G1NGS2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9103:DHX30
gene id: 9103:DHX30
uniprot id: G1MRB7
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

9103:GET1
gene id: 9103:GET1
uniprot id: G1NNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:RC3H2
gene id: 9103:RC3H2
uniprot id: G1N7I5
names: Subcellular Location Annotation
messages: P-body

9103:MAPK13
gene id: 9103:MAPK13
uniprot id: G1MQ62
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

9103:CFAP97
gene id: 9103:CFAP97
uniprot id: G1N3B1
names: Similarity
messages: Belongs to the CFAP97 family.

9103:LOC100548279
gene id: 9103:LOC100548279
uniprot id: G1NN73
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:ACSL5
gene id: 9103:ACSL5
uniprot id: G1NEL6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

9103:VANGL2
gene id: 9103:VANGL2
uniprot id: A0A803YAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

9103:COX2
gene id: 9103:COX2
uniprot id: A9XBE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9103:CALHM4
gene id: 9103:CALHM4
uniprot id: G1NKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9103:LEAP2
gene id: 9103:LEAP2
uniprot id: G1NA89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

9103:LOC100541738
gene id: 9103:LOC100541738
uniprot id: A0A803XME0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:LOC100541400
gene id: 9103:LOC100541400
uniprot id: G1NH22
names: Subcellular Location Annotation
messages: Membrane

9103:FOXP1
gene id: 9103:FOXP1
uniprot id: G1NB92
names: Subcellular Location Annotation
messages: Nucleus

9103:NDFIP2
gene id: 9103:NDFIP2
uniprot id: A0A803Y697
names: Subcellular Location Annotation
messages: Membrane

9103:HSPB3
gene id: 9103:HSPB3
uniprot id: A0A803XKI9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9103:LOC100544708
gene id: 9103:LOC100544708
uniprot id: G1NFC3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

9103:HAT1
gene id: 9103:HAT1
uniprot id: G3UQ01
names: Similarity
messages: Belongs to the HAT1 family.

9103:SEMA3D
gene id: 9103:SEMA3D
uniprot id: G1N178
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100550690
gene id: 9103:LOC100550690
uniprot id: A0A803Y2U0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:LOC104910884
gene id: 9103:LOC104910884
uniprot id: A0A803XTL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

9103:ABCA3
gene id: 9103:ABCA3
uniprot id: G1NCK8
names: Subcellular Location Annotation
messages: Membrane

9103:UPP1
gene id: 9103:UPP1
uniprot id: A0A803Y586
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

9103:NTN4
gene id: 9103:NTN4
uniprot id: G1NG05
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LACTB2
gene id: 9103:LACTB2
uniprot id: G1NG16
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

9103:LEPROTL1
gene id: 9103:LEPROTL1
uniprot id: G1N8V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9103:SLC25A38
gene id: 9103:SLC25A38
uniprot id: G1NGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

9103:MSTN
gene id: 9103:MSTN
uniprot id: O42221
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

9103:ZC3H14
gene id: 9103:ZC3H14
uniprot id: G1NK12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

9103:VCAM1
gene id: 9103:VCAM1
uniprot id: G1N4Y5
names: Subcellular Location Annotation
messages: Cell membrane

9103:LOC100542272
gene id: 9103:LOC100542272
uniprot id: G1NK25
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9103:PHF5A
gene id: 9103:PHF5A
uniprot id: G1NHU8
names: Similarity
messages: Belongs to the PHF5 family.

9103:LIPT1
gene id: 9103:LIPT1
uniprot id: G1NR74
names: Similarity
messages: Belongs to the LplA family.

9103:CDH18
gene id: 9103:CDH18
uniprot id: A0A803Y166
uniprot id: G1N1R6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9103:LOC100542185
gene id: 9103:LOC100542185
uniprot id: G1N799
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:PHACTR1
gene id: 9103:PHACTR1
uniprot id: A0A803XTX8
uniprot id: A0A803Y5N3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9103:SCP2
gene id: 9103:SCP2
uniprot id: G1NFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Mitochondrion

9103:SAR1A
gene id: 9103:SAR1A
uniprot id: G1N1C1
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

9103:SESN1
gene id: 9103:SESN1
uniprot id: A0A803YGV3
uniprot id: G1NL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9103:LOC104911970
gene id: 9103:LOC104911970
uniprot id: A0A803Y561
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:CEL
gene id: 9103:CEL
uniprot id: G1N3B6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9103:DLK2
gene id: 9103:DLK2
uniprot id: G1NEW7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:BMPR1A
gene id: 9103:BMPR1A
uniprot id: G3UPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9103:BMP10
gene id: 9103:BMP10
uniprot id: A0A803Y9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9103:UMPS
gene id: 9103:UMPS
uniprot id: G1NHQ5
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

9103:RIPOR1
gene id: 9103:RIPOR1
uniprot id: G1MTS0
names: Similarity
messages: Belongs to the RIPOR family.

9103:TMEM129
gene id: 9103:TMEM129
uniprot id: G3UQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

9103:CHRNA6
gene id: 9103:CHRNA6
uniprot id: A0A803XN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:STX19
gene id: 9103:STX19
uniprot id: G1NS42
names: Similarity
messages: Belongs to the syntaxin family.

9103:CA4
gene id: 9103:CA4
uniprot id: A0A803Y7B7
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9103:RNF152
gene id: 9103:RNF152
uniprot id: G1NR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

9103:UBE2D1
gene id: 9103:UBE2D1
uniprot id: G1MRH5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:SLC24A2
gene id: 9103:SLC24A2
uniprot id: A0A803Y5F8
uniprot id: G3UR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9103:P4HA2
gene id: 9103:P4HA2
uniprot id: A0A803YGZ4
uniprot id: G1N9J5
uniprot id: G1N9J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9103:GABRG2
gene id: 9103:GABRG2
uniprot id: A0A803YBW0
uniprot id: G1MUR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:LOC100545232
gene id: 9103:LOC100545232
uniprot id: G1N5S4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9103:LOC100548266
gene id: 9103:LOC100548266
uniprot id: G1NAI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:B3GNT7
gene id: 9103:B3GNT7
uniprot id: G1N7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:SARM1
gene id: 9103:SARM1
uniprot id: G1N1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARM1 family.
messages: axon

9103:SLC8A3
gene id: 9103:SLC8A3
uniprot id: G1NGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9103:IBSP
gene id: 9103:IBSP
uniprot id: G1N6F0
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

9103:SERPINA10
gene id: 9103:SERPINA10
uniprot id: G1NKG8
names: Similarity
messages: Belongs to the serpin family.

9103:RNF13
gene id: 9103:RNF13
uniprot id: G1NER0
names: Subcellular Location Annotation
messages: Membrane

9103:EOGT
gene id: 9103:EOGT
uniprot id: G1NAT4
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

9103:VPS35
gene id: 9103:VPS35
uniprot id: A0A803XXA0
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

9103:TCEA2
gene id: 9103:TCEA2
uniprot id: G1N4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

9103:MGST2
gene id: 9103:MGST2
uniprot id: G1MV99
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC104914423
gene id: 9103:LOC104914423
uniprot id: A0A803XM33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9103:ANXA13
gene id: 9103:ANXA13
uniprot id: A0A803YEQ7
uniprot id: G1NJ32
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9103:AGT
gene id: 9103:AGT
uniprot id: G1NHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

9103:LOC100540040
gene id: 9103:LOC100540040
uniprot id: G1N453
names: Subcellular Location Annotation
messages: Nucleus

9103:RUVBL1
gene id: 9103:RUVBL1
uniprot id: G1N5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9103:NLGN3
gene id: 9103:NLGN3
uniprot id: A0A803XZB0
uniprot id: G1N985
uniprot id: G3UUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9103:LOC100550137
gene id: 9103:LOC100550137
uniprot id: G1NI13
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

9103:ADCY8
gene id: 9103:ADCY8
uniprot id: G1NJG1
uniprot id: G3UNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9103:SORL1
gene id: 9103:SORL1
uniprot id: G1MT79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

9103:EVA1C
gene id: 9103:EVA1C
uniprot id: G1NNW4
names: Similarity
messages: Belongs to the EVA1 family.

9103:CDH22
gene id: 9103:CDH22
uniprot id: G1N841
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9103:FGGY
gene id: 9103:FGGY
uniprot id: G1NG87
names: Similarity
messages: Belongs to the FGGY kinase family.

9103:MEP1A
gene id: 9103:MEP1A
uniprot id: G1NN96
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:PPIL2
gene id: 9103:PPIL2
uniprot id: G1MQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

9103:GALNT1
gene id: 9103:GALNT1
uniprot id: G1N4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9103:LOC100544555
gene id: 9103:LOC100544555
uniprot id: G1NKH5
names: Similarity
messages: Belongs to the serpin family.

9103:ETV6
gene id: 9103:ETV6
uniprot id: A0A803YGK7
uniprot id: G1NM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:LOC104911865
gene id: 9103:LOC104911865
uniprot id: A0A803Y2J7
uniprot id: G1N2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane

9103:CPNE8
gene id: 9103:CPNE8
uniprot id: G1N690
names: Similarity
messages: Belongs to the copine family.

9103:LGI1
gene id: 9103:LGI1
uniprot id: G1N9F8
names: Subcellular Location Annotation
messages: Secreted

9103:PPARA
gene id: 9103:PPARA
uniprot id: G3UPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9103:CRYBB1
gene id: 9103:CRYBB1
uniprot id: G1N4W0
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9103:NEFM
gene id: 9103:NEFM
uniprot id: G1MQU5
names: Similarity
messages: Belongs to the intermediate filament family.

9103:BRIX1
gene id: 9103:BRIX1
uniprot id: A0A803YQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9103:DNAJB14
gene id: 9103:DNAJB14
uniprot id: G1NFH2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:GAL3ST1
gene id: 9103:GAL3ST1
uniprot id: A0A803YJ75
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9103:MEF2D
gene id: 9103:MEF2D
uniprot id: A0A803Y0Y9
uniprot id: G1MPS9
names: Subcellular Location Annotation
messages: Nucleus

9103:MTFR1
gene id: 9103:MTFR1
uniprot id: G1NFA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9103:PYCR1
gene id: 9103:PYCR1
uniprot id: A0A803Y6F9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9103:SLC28A3
gene id: 9103:SLC28A3
uniprot id: A0A803Y9U5
uniprot id: A0A803YBZ0
uniprot id: A0A803YKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9103:DARS1
gene id: 9103:DARS1
uniprot id: G1NIS2
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

9103:CD28
gene id: 9103:CD28
uniprot id: G1N9E3
names: Subcellular Location Annotation
messages: Membrane

9103:GOLPH3L
gene id: 9103:GOLPH3L
uniprot id: G1MPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9103:RXRA
gene id: 9103:RXRA
uniprot id: A0A803XQT3
uniprot id: G1N4W9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

9103:EIF4E1B
gene id: 9103:EIF4E1B
uniprot id: A0A803Y0X3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9103:MDM2
gene id: 9103:MDM2
uniprot id: G1NDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

9103:WFIKKN2
gene id: 9103:WFIKKN2
uniprot id: G1N923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

9103:TUBD1
gene id: 9103:TUBD1
uniprot id: G1N664
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Nucleus
messages: centriole
messages: cilium

9103:TMEM9
gene id: 9103:TMEM9
uniprot id: G1MT73
names: Similarity
messages: Belongs to the TMEM9 family.

9103:LOC104913819
gene id: 9103:LOC104913819
uniprot id: G1N8S9
names: Similarity
messages: Belongs to the NDK family.

9103:SEC22B
gene id: 9103:SEC22B
uniprot id: G1MZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9103:AMPD1
gene id: 9103:AMPD1
uniprot id: A0A803Y9M9
uniprot id: G1NLT9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

9103:PKN3
gene id: 9103:PKN3
uniprot id: G1MZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

9103:SERPINC1
gene id: 9103:SERPINC1
uniprot id: G3UNT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

9103:LOC100549991
gene id: 9103:LOC100549991
uniprot id: G1NRE1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9103:ATP7B
gene id: 9103:ATP7B
uniprot id: A0A803YPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

9103:VPS37C
gene id: 9103:VPS37C
uniprot id: A0A803XM91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9103:SBDS
gene id: 9103:SBDS
uniprot id: G3UPX1
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

9103:DMRTB1
gene id: 9103:DMRTB1
uniprot id: G1NFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9103:DTX2
gene id: 9103:DTX2
uniprot id: A0A803YA81
uniprot id: A0A803YI51
uniprot id: A0A803YR13
uniprot id: G1MX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9103:EWSR1
gene id: 9103:EWSR1
uniprot id: G1N180
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9103:RFLNA
gene id: 9103:RFLNA
uniprot id: A0A803YGR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

9103:LOC100547885
gene id: 9103:LOC100547885
uniprot id: A0A803YCG1
uniprot id: G1MTX1
uniprot id: G3USN2
uniprot id: G3UTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9103:MC3R
gene id: 9103:MC3R
uniprot id: G1NRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

9103:LOC100540809
gene id: 9103:LOC100540809
uniprot id: A0A803XSG4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:GLRB
gene id: 9103:GLRB
uniprot id: G1MSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

9103:LOC104914064
gene id: 9103:LOC104914064
uniprot id: A0A803XUZ5
names: Similarity
messages: Belongs to the RIPOR family.

9103:LOC100538502
gene id: 9103:LOC100538502
uniprot id: G3USW3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:FAM110B
gene id: 9103:FAM110B
uniprot id: G1NRR2
names: Similarity
messages: Belongs to the FAM110 family.

9103:ADGRF5
gene id: 9103:ADGRF5
uniprot id: G1NN99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9103:AOX1
gene id: 9103:AOX1
uniprot id: G1N6E5
uniprot id: M1ZMM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9103:LOC100542202
gene id: 9103:LOC100542202
uniprot id: G1NRI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:NEK8
gene id: 9103:NEK8
uniprot id: A0A803XL58
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

9103:ESR2
gene id: 9103:ESR2
uniprot id: G1NLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9103:LOC100540190
gene id: 9103:LOC100540190
uniprot id: G1MZV0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:MANEA
gene id: 9103:MANEA
uniprot id: G1NLI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:CLDN18
gene id: 9103:CLDN18
uniprot id: G1MUI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9103:HTR1E
gene id: 9103:HTR1E
uniprot id: G1NRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:PLCL2
gene id: 9103:PLCL2
uniprot id: G1NEL4
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

9103:BMS1
gene id: 9103:BMS1
uniprot id: G1MRC6
names: Subcellular Location Annotation
messages: nucleolus

9103:TLR5
gene id: 9103:TLR5
uniprot id: G1NRW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9103:MIS18A
gene id: 9103:MIS18A
uniprot id: G1NNV5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

9103:BCL2L1
gene id: 9103:BCL2L1
uniprot id: G1N5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

9103:ARV1
gene id: 9103:ARV1
uniprot id: A0A803Y5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

9103:NEU2
gene id: 9103:NEU2
uniprot id: G1MSG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9103:TLR3
gene id: 9103:TLR3
uniprot id: G1NFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9103:LOC100539376
gene id: 9103:LOC100539376
uniprot id: A0A803XK94
names: Subcellular Location Annotation
messages: Membrane

9103:ADIPOR2
gene id: 9103:ADIPOR2
uniprot id: G1NL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9103:MPI
gene id: 9103:MPI
uniprot id: G1MTS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9103:NMB
gene id: 9103:NMB
uniprot id: G1MQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

9103:GCAT
gene id: 9103:GCAT
uniprot id: G1NIM8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

9103:PDE8A
gene id: 9103:PDE8A
uniprot id: G1N6Q3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:CFAP206
gene id: 9103:CFAP206
uniprot id: G1NLP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme

9103:RPL27A
gene id: 9103:RPL27A
uniprot id: G1N3Y5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9103:PEX12
gene id: 9103:PEX12
uniprot id: G1MYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.
messages: Membrane
messages: Peroxisome membrane

9103:SRPX
gene id: 9103:SRPX
uniprot id: G1NP52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CFLAR
gene id: 9103:CFLAR
uniprot id: G1N708
names: Similarity
messages: Belongs to the peptidase C14A family.

9103:COPS7B
gene id: 9103:COPS7B
uniprot id: G1N7Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9103:PDE5A
gene id: 9103:PDE5A
uniprot id: G1NE52
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:ING3
gene id: 9103:ING3
uniprot id: G1N979
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9103:CTSO
gene id: 9103:CTSO
uniprot id: G1MS56
names: Similarity
messages: Belongs to the peptidase C1 family.

9103:GGA1
gene id: 9103:GGA1
uniprot id: G1NIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

9103:LOC100548306
gene id: 9103:LOC100548306
uniprot id: G1NA83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

9103:SLC19A1
gene id: 9103:SLC19A1
uniprot id: G1MSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: Transporter that mediates the import of reduced folates.

9103:CTSE
gene id: 9103:CTSE
uniprot id: G1MWJ2
names: Similarity
messages: Belongs to the peptidase A1 family.

9103:YAE1
gene id: 9103:YAE1
uniprot id: G1NI14
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:GNA11
gene id: 9103:GNA11
uniprot id: P45645
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-alpha family. G(q) subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.

9103:HAL
gene id: 9103:HAL
uniprot id: G1NG29
names: Similarity
messages: Belongs to the PAL/histidase family.

9103:ATP6V0A1
gene id: 9103:ATP6V0A1
uniprot id: A0A803YAA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

9103:MRPS25
gene id: 9103:MRPS25
uniprot id: G1NDA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

9103:LOC100542160
gene id: 9103:LOC100542160
uniprot id: G1NQS4
names: Similarity
messages: Belongs to the peptidase C19 family.

9103:MED16
gene id: 9103:MED16
uniprot id: G1MVG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9103:LOC100551396
gene id: 9103:LOC100551396
uniprot id: H9H1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9103:POMT1
gene id: 9103:POMT1
uniprot id: G1N2B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9103:RBPJ
gene id: 9103:RBPJ
uniprot id: A0A803YJ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

9103:NMT1
gene id: 9103:NMT1
uniprot id: G1MPW4
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

9103:LOC104913852
gene id: 9103:LOC104913852
uniprot id: A0A803Y3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9103:THEMIS2
gene id: 9103:THEMIS2
uniprot id: G1MQX9
names: Similarity
messages: Belongs to the themis family.

9103:CREB1
gene id: 9103:CREB1
uniprot id: G1N8F7
names: Subcellular Location Annotation
messages: Nucleus

9103:AIDA
gene id: 9103:AIDA
uniprot id: G1N9R3
names: Similarity
messages: Belongs to the AIDA family.

9103:CD44
gene id: 9103:CD44
uniprot id: G1ND31
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

9103:SF3B6
gene id: 9103:SF3B6
uniprot id: G1NMP7
names: Subcellular Location Annotation
messages: Nucleus

9103:HTR4
gene id: 9103:HTR4
uniprot id: A0A803Y6H1
uniprot id: A0A803YBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

9103:NQO2
gene id: 9103:NQO2
uniprot id: G1MZ86
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

9103:C7H2orf88
gene id: 9103:C7H2orf88
uniprot id: A0A803Y6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

9103:KCTD10
gene id: 9103:KCTD10
uniprot id: G1N3E4
names: Similarity
messages: Belongs to the BACURD family.

9103:KCNJ13
gene id: 9103:KCNJ13
uniprot id: G1MSR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9103:AMIGO2
gene id: 9103:AMIGO2
uniprot id: A0A803XZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

9103:SFXN2
gene id: 9103:SFXN2
uniprot id: G1ND51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9103:TASOR
gene id: 9103:TASOR
uniprot id: G1N381
names: Similarity
messages: Belongs to the TASOR family.

9103:RPL9
gene id: 9103:RPL9
uniprot id: G1NI74
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

9103:ME1
gene id: 9103:ME1
uniprot id: G1NLV4
uniprot id: Q90XC1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9103:P4HA1
gene id: 9103:P4HA1
uniprot id: G1N1U2
uniprot id: G3UU74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9103:MSH5
gene id: 9103:MSH5
uniprot id: G1NRT2
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

9103:TJAP1
gene id: 9103:TJAP1
uniprot id: A0A803XUQ6
names: Subcellular Location Annotation
messages: Membrane

9103:LIN7C
gene id: 9103:LIN7C
uniprot id: G1NJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

9103:SEPTIN6
gene id: 9103:SEPTIN6
uniprot id: G1N6Z5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9103:DOLK
gene id: 9103:DOLK
uniprot id: G1NRM3
names: Similarity
messages: Belongs to the polyprenol kinase family.

9103:LOC100544289
gene id: 9103:LOC100544289
uniprot id: G1NGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

9103:SARAF
gene id: 9103:SARAF
uniprot id: G3UPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:C1H2orf49
gene id: 9103:C1H2orf49
uniprot id: G1NPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

9103:LOC100538756
gene id: 9103:LOC100538756
uniprot id: G1MTR8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:INHBA
gene id: 9103:INHBA
uniprot id: A0A803XKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9103:USP14
gene id: 9103:USP14
uniprot id: A0A803XZ58
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

9103:ROMO1
gene id: 9103:ROMO1
uniprot id: A0A803XTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

9103:ENTPD5
gene id: 9103:ENTPD5
uniprot id: G1NJ21
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9103:CD2
gene id: 9103:CD2
uniprot id: G1NNP8
names: Subcellular Location Annotation
messages: Membrane

9103:NDEL1
gene id: 9103:NDEL1
uniprot id: A0A803XUC7
uniprot id: G1MU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

9103:TMPRSS6
gene id: 9103:TMPRSS6
uniprot id: G1NJ34
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NPY
gene id: 9103:NPY
uniprot id: G1NDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

9103:LOC104914521
gene id: 9103:LOC104914521
uniprot id: A0A803XTW7
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9103:TMLHE
gene id: 9103:TMLHE
uniprot id: G1N0Z8
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

9103:SSTR2
gene id: 9103:SSTR2
uniprot id: A0A803YL84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

9103:LOC100546662
gene id: 9103:LOC100546662
uniprot id: G1MRY6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:CYP1A5
gene id: 9103:CYP1A5
uniprot id: Q56D25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9103:CHRNB4
gene id: 9103:CHRNB4
uniprot id: G1MWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:CLCN3
gene id: 9103:CLCN3
uniprot id: G1MUE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9103:SIGIRR
gene id: 9103:SIGIRR
uniprot id: G1MUL1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9103:NGF
gene id: 9103:NGF
uniprot id: G1NRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

9103:CAPN5
gene id: 9103:CAPN5
uniprot id: G1NQT4
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:CAMSAP1
gene id: 9103:CAMSAP1
uniprot id: G1MVZ2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9103:ABCC5
gene id: 9103:ABCC5
uniprot id: A0A803XP92
names: Subcellular Location Annotation
messages: Membrane

9103:SLC12A9
gene id: 9103:SLC12A9
uniprot id: G1N8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9103:MUL1
gene id: 9103:MUL1
uniprot id: G1N2C7
names: Subcellular Location Annotation
messages: Membrane

9103:PFDN4
gene id: 9103:PFDN4
uniprot id: G1NAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9103:FAM162B
gene id: 9103:FAM162B
uniprot id: G1NKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

9103:NRF1
gene id: 9103:NRF1
uniprot id: G1MUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

9103:LOC100549590
gene id: 9103:LOC100549590
uniprot id: G1MYP6
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9103:INTS14
gene id: 9103:INTS14
uniprot id: G1NBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

9103:RPL3
gene id: 9103:RPL3
uniprot id: G1NIE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

9103:ZRANB1
gene id: 9103:ZRANB1
uniprot id: G1NGN3
names: Similarity
messages: Belongs to the peptidase C64 family.

9103:GK
gene id: 9103:GK
uniprot id: G3UUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

9103:SYT15
gene id: 9103:SYT15
uniprot id: A0A803XN75
uniprot id: G1MU16
names: Similarity
messages: Belongs to the synaptotagmin family.

9103:STRADA
gene id: 9103:STRADA
uniprot id: G1MSJ4
uniprot id: G3UT21
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

9103:LOC100548260
gene id: 9103:LOC100548260
uniprot id: G3URB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ENY2
gene id: 9103:ENY2
uniprot id: A0A803XMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

9103:HMGB1
gene id: 9103:HMGB1
uniprot id: G1NQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9103:EIF2D
gene id: 9103:EIF2D
uniprot id: G1MX71
names: Similarity
messages: Belongs to the eIF2D family.

9103:KPNA2
gene id: 9103:KPNA2
uniprot id: G1N6L6
names: Similarity
messages: Belongs to the importin alpha family.

9103:CSGALNACT1
gene id: 9103:CSGALNACT1
uniprot id: G1MZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9103:DEGS2
gene id: 9103:DEGS2
uniprot id: G1NKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:MDFI
gene id: 9103:MDFI
uniprot id: G1N368
names: Similarity
messages: Belongs to the MDFI family.

9103:LOC100540439
gene id: 9103:LOC100540439
uniprot id: A0A803YE04
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:GOLGA5
gene id: 9103:GOLGA5
uniprot id: G1NKD1
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

9103:IL1RN
gene id: 9103:IL1RN
uniprot id: A3DTN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

9103:ND2
gene id: 9103:ND2
uniprot id: Q955U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9103:SLC35A4
gene id: 9103:SLC35A4
uniprot id: G1NR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9103:LOC100548069
gene id: 9103:LOC100548069
uniprot id: H9H0P0
names: Subcellular Location Annotation
messages: Membrane

9103:CCL20
gene id: 9103:CCL20
uniprot id: G1N2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9103:CEP170B
gene id: 9103:CEP170B
uniprot id: A0A803XZJ5
uniprot id: G1NL58
names: Similarity
messages: Belongs to the CEP170 family.

9103:DCT
gene id: 9103:DCT
uniprot id: G1NPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

9103:POLR2D
gene id: 9103:POLR2D
uniprot id: G1MR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

9103:GALT
gene id: 9103:GALT
uniprot id: A0A803YHK7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

9103:SYNE3
gene id: 9103:SYNE3
uniprot id: A0A803XN54
names: Similarity
messages: Belongs to the nesprin family.

9103:TRDMT1
gene id: 9103:TRDMT1
uniprot id: A0A803YAM3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

9103:ADGRD1
gene id: 9103:ADGRD1
uniprot id: G1MTR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:MMD2
gene id: 9103:MMD2
uniprot id: A0A803Y087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9103:LOC100545074
gene id: 9103:LOC100545074
uniprot id: G1NCV7
names: Similarity
messages: Belongs to the CAND family.

9103:FAM124B
gene id: 9103:FAM124B
uniprot id: G1N0E1
names: Similarity
messages: Belongs to the FAM124 family.

9103:EGR1
gene id: 9103:EGR1
uniprot id: G1NB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

9103:GNG12
gene id: 9103:GNG12
uniprot id: G1NHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9103:LOC100548675
gene id: 9103:LOC100548675
uniprot id: G1NRE6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

9103:LOC100542155
gene id: 9103:LOC100542155
uniprot id: A0A803Y1N2
names: Subcellular Location Annotation
messages: Nucleus

9103:FLCN
gene id: 9103:FLCN
uniprot id: G1MYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

9103:GUK1
gene id: 9103:GUK1
uniprot id: G1MUI4
names: Similarity
messages: Belongs to the guanylate kinase family.

9103:UROS
gene id: 9103:UROS
uniprot id: G1NGQ3
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

9103:CRYBA2
gene id: 9103:CRYBA2
uniprot id: H9H0K9
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9103:TNFRSF4
gene id: 9103:TNFRSF4
uniprot id: G1MW38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TRMT2B
gene id: 9103:TRMT2B
uniprot id: G1NAL5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100550313
gene id: 9103:LOC100550313
uniprot id: G1N3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9103:FAM163B
gene id: 9103:FAM163B
uniprot id: G1N4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9103:CCM2
gene id: 9103:CCM2
uniprot id: A0A803XUD1
uniprot id: G1MVK6
names: Similarity
messages: Belongs to the CCM2 family.

9103:KCNJ15
gene id: 9103:KCNJ15
uniprot id: A0A803YDL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9103:ZDHHC7
gene id: 9103:ZDHHC7
uniprot id: G1N5W1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:NDUFV3
gene id: 9103:NDUFV3
uniprot id: G1NP18
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

9103:MADCAM1
gene id: 9103:MADCAM1
uniprot id: A0A803YC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9103:LOC104911731
gene id: 9103:LOC104911731
uniprot id: A0A803YD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:KATNA1
gene id: 9103:KATNA1
uniprot id: G1NJ12
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

9103:NDUFV1
gene id: 9103:NDUFV1
uniprot id: G1MY60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

9103:SLC20A1
gene id: 9103:SLC20A1
uniprot id: G1MX62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

9103:WDR24
gene id: 9103:WDR24
uniprot id: G1NBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

9103:SLC7A4
gene id: 9103:SLC7A4
uniprot id: G1NB48
names: Subcellular Location Annotation
messages: Membrane

9103:HNF4A
gene id: 9103:HNF4A
uniprot id: G1MXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9103:LOC100543573
gene id: 9103:LOC100543573
uniprot id: Q4VTT6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

9103:CCN4
gene id: 9103:CCN4
uniprot id: G1NJM6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:ST6GALNAC1
gene id: 9103:ST6GALNAC1
uniprot id: G1MY94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:ZDHHC12
gene id: 9103:ZDHHC12
uniprot id: G1MZA7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:UNC50
gene id: 9103:UNC50
uniprot id: A0A803XNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

9103:TOP3A
gene id: 9103:TOP3A
uniprot id: G1N063
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

9103:GSKIP
gene id: 9103:GSKIP
uniprot id: A0A803YQ19
names: Similarity
messages: Belongs to the GSKIP family.

9103:PCK1
gene id: 9103:PCK1
uniprot id: G1NA26
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9103:CHST10
gene id: 9103:CHST10
uniprot id: G1NPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:NPL
gene id: 9103:NPL
uniprot id: G1MSX9
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

9103:LOC100540027
gene id: 9103:LOC100540027
uniprot id: A0A803Y0G7
uniprot id: G1N2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

9103:XKR5
gene id: 9103:XKR5
uniprot id: G1NN40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9103:LHFPL6
gene id: 9103:LHFPL6
uniprot id: A0A803YRA5
names: Subcellular Location Annotation
messages: Membrane

9103:ENPEP
gene id: 9103:ENPEP
uniprot id: A0A803XSJ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

9103:POLL
gene id: 9103:POLL
uniprot id: G1NCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

9103:MBTD1
gene id: 9103:MBTD1
uniprot id: A0A803YN29
names: Subcellular Location Annotation
messages: Nucleus

9103:POLR3A
gene id: 9103:POLR3A
uniprot id: G1N259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

9103:CHRM2
gene id: 9103:CHRM2
uniprot id: G1NRY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

9103:GINS4
gene id: 9103:GINS4
uniprot id: G1MTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

9103:CD99L2
gene id: 9103:CD99L2
uniprot id: G1N7Q0
names: Similarity
messages: Belongs to the CD99 family.

9103:POU2F1
gene id: 9103:POU2F1
uniprot id: A0A803XQ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

9103:LOC100546836
gene id: 9103:LOC100546836
uniprot id: G1N481
names: Similarity
messages: Belongs to the FBPase class 1 family.

9103:SUCLA2
gene id: 9103:SUCLA2
uniprot id: G1NQ49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

9103:LIPI
gene id: 9103:LIPI
uniprot id: G1NNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9103:FUT6
gene id: 9103:FUT6
uniprot id: G1NRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

9103:SLC5A9
gene id: 9103:SLC5A9
uniprot id: G1NEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9103:LCA5L
gene id: 9103:LCA5L
uniprot id: G3USC2
names: Similarity
messages: Belongs to the LCA5 family.

9103:OPTC
gene id: 9103:OPTC
uniprot id: G1NAT0
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9103:B3GALT5
gene id: 9103:B3GALT5
uniprot id: A0A803YMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:LOC100542101
gene id: 9103:LOC100542101
uniprot id: G1MVH4
names: Similarity
messages: Belongs to the intermediate filament family.

9103:CTNNA1
gene id: 9103:CTNNA1
uniprot id: G1MRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

9103:CAVIN1
gene id: 9103:CAVIN1
uniprot id: G1MWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9103:GPCPD1
gene id: 9103:GPCPD1
uniprot id: G1N6Q8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9103:SERPINE3
gene id: 9103:SERPINE3
uniprot id: A0A803YJL6
names: Similarity
messages: Belongs to the serpin family.

9103:SRM
gene id: 9103:SRM
uniprot id: A0A803XL48
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

9103:LOC104909481
gene id: 9103:LOC104909481
uniprot id: G1MRW3
names: Similarity
messages: Belongs to the exportin family.

9103:TMEM229B
gene id: 9103:TMEM229B
uniprot id: G1NRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

9103:LOC100547769
gene id: 9103:LOC100547769
uniprot id: G1MXV7
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

9103:CACNG5
gene id: 9103:CACNG5
uniprot id: G1N656
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

9103:SNX20
gene id: 9103:SNX20
uniprot id: G1MZU5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

9103:ABCB9
gene id: 9103:ABCB9
uniprot id: A0A803YK78
uniprot id: G1MWW7
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100546401
gene id: 9103:LOC100546401
uniprot id: A0A803Y843
names: Similarity
messages: Belongs to the SLBP family.

9103:GALC
gene id: 9103:GALC
uniprot id: G1NJZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

9103:SETD7
gene id: 9103:SETD7
uniprot id: G1MV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

9103:DIPK1C
gene id: 9103:DIPK1C
uniprot id: G1N801
names: Similarity
messages: Belongs to the DIPK family.

9103:LOC109363685
gene id: 9103:LOC109363685
uniprot id: G3US71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

9103:MFSD10
gene id: 9103:MFSD10
uniprot id: G1NJZ6
names: Subcellular Location Annotation
messages: Membrane

9103:ARHGEF12
gene id: 9103:ARHGEF12
uniprot id: G1MTT6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

9103:SELENBP1
gene id: 9103:SELENBP1
uniprot id: G1MR11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

9103:KCNA10
gene id: 9103:KCNA10
uniprot id: G1NRF8
names: Subcellular Location Annotation
messages: Membrane

9103:LOC104913559
gene id: 9103:LOC104913559
uniprot id: A0A803YA42
names: Subcellular Location Annotation
messages: Nucleus

9103:INHA
gene id: 9103:INHA
uniprot id: Q98SQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

9103:ATF1
gene id: 9103:ATF1
uniprot id: A0A803Y0X9
uniprot id: A0A803Y1W9
uniprot id: H9H1S8
names: Subcellular Location Annotation
messages: Nucleus

9103:TMEM184A
gene id: 9103:TMEM184A
uniprot id: G1MUN7
names: Subcellular Location Annotation
messages: Membrane

9103:PRPF18
gene id: 9103:PRPF18
uniprot id: A0A803YFF3
uniprot id: G1N0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

9103:SCN3B
gene id: 9103:SCN3B
uniprot id: G1MSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

9103:SF3A1
gene id: 9103:SF3A1
uniprot id: H9H083
names: Subcellular Location Annotation
messages: Nucleus

9103:GPBP1
gene id: 9103:GPBP1
uniprot id: G1NBC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

9103:COPS4
gene id: 9103:COPS4
uniprot id: G1N797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

9103:LPAR1
gene id: 9103:LPAR1
uniprot id: G1N932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

9103:ZNF330
gene id: 9103:ZNF330
uniprot id: G1MW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

9103:LACC1
gene id: 9103:LACC1
uniprot id: A0A803YFA8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

9103:DPY30
gene id: 9103:DPY30
uniprot id: G1NFR9
names: Similarity
messages: Belongs to the dpy-30 family.

9103:LOC100542800
gene id: 9103:LOC100542800
uniprot id: G1NS52
names: Similarity
messages: Belongs to the actin family.

9103:PARP1
gene id: 9103:PARP1
uniprot id: G3UUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

9103:LOC100547975
gene id: 9103:LOC100547975
uniprot id: A0A803YSA1
names: Similarity
messages: Belongs to the phospholipase D family.

9103:STS
gene id: 9103:STS
uniprot id: G1NP33
names: Similarity
messages: Belongs to the sulfatase family.

9103:DNAL4
gene id: 9103:DNAL4
uniprot id: G1NL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9103:RAD1
gene id: 9103:RAD1
uniprot id: G1MVY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

9103:GPATCH1
gene id: 9103:GPATCH1
uniprot id: A0A803Y9Z2
names: Similarity
messages: Belongs to the GPATCH1 family.

9103:SEC13
gene id: 9103:SEC13
uniprot id: G1NCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

9103:STMN1
gene id: 9103:STMN1
uniprot id: G1MV02
names: Similarity
messages: Belongs to the stathmin family.

9103:KCNJ16
gene id: 9103:KCNJ16
uniprot id: G1N4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9103:ABRACL
gene id: 9103:ABRACL
uniprot id: A0A803XP11
names: Similarity
messages: Belongs to the costars family.

9103:GABRG1
gene id: 9103:GABRG1
uniprot id: G1NHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:BCHE
gene id: 9103:BCHE
uniprot id: A0A803XNP2
uniprot id: A0A803XRH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9103:MGMT
gene id: 9103:MGMT
uniprot id: A0A803YCD1
uniprot id: G1NGZ4
names: Similarity
messages: Belongs to the MGMT family.

9103:BCAT1
gene id: 9103:BCAT1
uniprot id: G1NLL0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

9103:CCK
gene id: 9103:CCK
uniprot id: A0A803YKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

9103:ACSF2
gene id: 9103:ACSF2
uniprot id: G1NA59
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9103:CWC15
gene id: 9103:CWC15
uniprot id: G1NQM0
names: Similarity
messages: Belongs to the CWC15 family.

9103:ATAD1
gene id: 9103:ATAD1
uniprot id: G1MS20
names: Similarity
messages: Belongs to the AAA ATPase family.

9103:PARP9
gene id: 9103:PARP9
uniprot id: G1NI39
names: Similarity
messages: Belongs to the ARTD/PARP family.

9103:RCAN3
gene id: 9103:RCAN3
uniprot id: G1N2N5
names: Similarity
messages: Belongs to the RCAN family.

9103:HOXD11
gene id: 9103:HOXD11
uniprot id: G1NBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9103:PTHLH
gene id: 9103:PTHLH
uniprot id: G1NM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

9103:APPL2
gene id: 9103:APPL2
uniprot id: G1NJS4
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9103:AP2A2
gene id: 9103:AP2A2
uniprot id: G3UQ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

9103:LOC100546481
gene id: 9103:LOC100546481
uniprot id: G1NMI9
names: Similarity
messages: Belongs to the cystatin family.

9103:LOC109365718
gene id: 9103:LOC109365718
uniprot id: A0A803YKV9
names: Subcellular Location Annotation
messages: acrosome

9103:GHRHR
gene id: 9103:GHRHR
uniprot id: G1MSI5
uniprot id: G3UU45
names: Subcellular Location Annotation
messages: Membrane

9103:ARHGDIB
gene id: 9103:ARHGDIB
uniprot id: G1NGY1
names: Similarity
messages: Belongs to the Rho GDI family.

9103:DYRK1A
gene id: 9103:DYRK1A
uniprot id: A0A803Y3N4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9103:LOC100545895
gene id: 9103:LOC100545895
uniprot id: G1MYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9103:DTD2
gene id: 9103:DTD2
uniprot id: G1NIJ5
names: Similarity
messages: Belongs to the DTD family.

9103:INSR
gene id: 9103:INSR
uniprot id: G1N117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9103:LOC100546179
gene id: 9103:LOC100546179
uniprot id: G1NE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:DDO
gene id: 9103:DDO
uniprot id: A0A803Y2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9103:LOC100550096
gene id: 9103:LOC100550096
uniprot id: G1MQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:HSDL1
gene id: 9103:HSDL1
uniprot id: G1MQA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:BDH1
gene id: 9103:BDH1
uniprot id: G1N528
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:CALHM5
gene id: 9103:CALHM5
uniprot id: A0A803XPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9103:PCNA
gene id: 9103:PCNA
uniprot id: G1MPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

9103:GRIN2B
gene id: 9103:GRIN2B
uniprot id: G1NH69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

9103:GEMIN2
gene id: 9103:GEMIN2
uniprot id: G1NIW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

9103:INS
gene id: 9103:INS
uniprot id: G1N7C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

9103:RBM22
gene id: 9103:RBM22
uniprot id: G1N3L9
names: Similarity
messages: Belongs to the SLT11 family.

9103:UBE3A
gene id: 9103:UBE3A
uniprot id: G1NPJ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

9103:HDAC7
gene id: 9103:HDAC7
uniprot id: A0A803YKY5
uniprot id: H9H1R9
uniprot id: H9H296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

9103:CUL4B
gene id: 9103:CUL4B
uniprot id: G1N6L9
names: Similarity
messages: Belongs to the cullin family.

9103:SSTR4
gene id: 9103:SSTR4
uniprot id: G1MVY2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:XPNPEP1
gene id: 9103:XPNPEP1
uniprot id: G1NE61
names: Similarity
messages: Belongs to the peptidase M24B family.

9103:OXTR
gene id: 9103:OXTR
uniprot id: G1NCK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:MCM8
gene id: 9103:MCM8
uniprot id: G1N6W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

9103:C1GALT1
gene id: 9103:C1GALT1
uniprot id: G1NBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

9103:GMNN
gene id: 9103:GMNN
uniprot id: G1N7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

9103:AASDHPPT
gene id: 9103:AASDHPPT
uniprot id: G1NQI4
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

9103:NOX1
gene id: 9103:NOX1
uniprot id: A0A803YDB5
uniprot id: G1MY90
uniprot id: G5E808
names: Subcellular Location Annotation
messages: Membrane

9103:AKT1
gene id: 9103:AKT1
uniprot id: G1NL49
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

9103:UTP14A
gene id: 9103:UTP14A
uniprot id: G1MSX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

9103:CTNNB1
gene id: 9103:CTNNB1
uniprot id: A0A803XZ57
uniprot id: G1NGP2
names: Similarity
messages: Belongs to the beta-catenin family.

9103:LOC100544729
gene id: 9103:LOC100544729
uniprot id: G1NBE5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9103:SLC39A6
gene id: 9103:SLC39A6
uniprot id: G1N669
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100539684
gene id: 9103:LOC100539684
uniprot id: G1N273
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:CAVIN4
gene id: 9103:CAVIN4
uniprot id: G1N6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9103:HHATL
gene id: 9103:HHATL
uniprot id: G1MU11
names: Subcellular Location Annotation
messages: Membrane

9103:NMD3
gene id: 9103:NMD3
uniprot id: G1NDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

9103:GOSR2
gene id: 9103:GOSR2
uniprot id: A0A803XN50
names: Subcellular Location Annotation
messages: Membrane

9103:LOC104911986
gene id: 9103:LOC104911986
uniprot id: A0A803YSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9103:CHCHD6
gene id: 9103:CHCHD6
uniprot id: A0A803XNU5
uniprot id: G1N6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9103:IL8
gene id: 9103:IL8
uniprot id: A2VBZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

9103:LOC100547404
gene id: 9103:LOC100547404
uniprot id: G1NPZ8
names: Similarity
messages: Belongs to the globin family.

9103:PRPF38A
gene id: 9103:PRPF38A
uniprot id: G1NFA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

9103:CD47
gene id: 9103:CD47
uniprot id: A0A803XL87
uniprot id: G1NNJ4
uniprot id: G1NNK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:GHRL
gene id: 9103:GHRL
uniprot id: Q7T1B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Secreted

9103:TULP3
gene id: 9103:TULP3
uniprot id: G1NMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

9103:PPDPF
gene id: 9103:PPDPF
uniprot id: G1N3X5
names: Similarity
messages: Belongs to the PPDPF family.

9103:APLN
gene id: 9103:APLN
uniprot id: A0A803XUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

9103:SMC3
gene id: 9103:SMC3
uniprot id: G1NEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

9103:GFAP
gene id: 9103:GFAP
uniprot id: G1MPT3
names: Similarity
messages: Belongs to the intermediate filament family.

9103:LOC100546355
gene id: 9103:LOC100546355
uniprot id: G1MUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9103:LOC100551093
gene id: 9103:LOC100551093
uniprot id: G1NPB1
names: Similarity
messages: Belongs to the taxilin family.

9103:POU1F1
gene id: 9103:POU1F1
uniprot id: Q05749
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the POU transcription factor family. Class-1 subfamily.
messages: Nucleus
messages: Pituitary gland.
messages: The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
messages: Transcription factor that activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.

9103:CD36
gene id: 9103:CD36
uniprot id: G1N2C2
names: Similarity
messages: Belongs to the CD36 family.

9103:RAB38
gene id: 9103:RAB38
uniprot id: G1NQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9103:LOC100546474
gene id: 9103:LOC100546474
uniprot id: A0A803YPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

9103:DIS3L
gene id: 9103:DIS3L
uniprot id: G1NBV5
names: Similarity
messages: Belongs to the RNR ribonuclease family.

9103:LOC100548663
gene id: 9103:LOC100548663
uniprot id: G1NR57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CKMT2
gene id: 9103:CKMT2
uniprot id: G1N717
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9103:LOC100540856
gene id: 9103:LOC100540856
uniprot id: G1N876
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

9103:ATP6V1E1
gene id: 9103:ATP6V1E1
uniprot id: G1NL74
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

9103:CMC2
gene id: 9103:CMC2
uniprot id: G1N4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9103:AGPAT3
gene id: 9103:AGPAT3
uniprot id: G1NP28
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9103:E2F1
gene id: 9103:E2F1
uniprot id: G1MU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9103:SLC2A1
gene id: 9103:SLC2A1
uniprot id: G1N5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

9103:IL18
gene id: 9103:IL18
uniprot id: G1MZF3
uniprot id: Q8AV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Secreted

9103:ABCA1
gene id: 9103:ABCA1
uniprot id: G1N6S3
names: Subcellular Location Annotation
messages: Membrane

9103:ORMDL2
gene id: 9103:ORMDL2
uniprot id: G1N636
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9103:HNRNPH1
gene id: 9103:HNRNPH1
uniprot id: G1N620
names: Subcellular Location Annotation
messages: nucleoplasm

9103:LOC100548537
gene id: 9103:LOC100548537
uniprot id: G3UPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

9103:GJA4
gene id: 9103:GJA4
uniprot id: G5E807
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9103:CFAP298
gene id: 9103:CFAP298
uniprot id: G1NNV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

9103:HARBI1
gene id: 9103:HARBI1
uniprot id: G1NES5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

9103:NKAIN3
gene id: 9103:NKAIN3
uniprot id: A0A803Y7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9103:EGFL7
gene id: 9103:EGFL7
uniprot id: A0A803XQ99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GUF1
gene id: 9103:GUF1
uniprot id: A0A803YAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

9103:LOC100549268
gene id: 9103:LOC100549268
uniprot id: M1ZMK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9103:RSPO1
gene id: 9103:RSPO1
uniprot id: G1MW47
names: Similarity
messages: Belongs to the R-spondin family.

9103:GSN
gene id: 9103:GSN
uniprot id: A0A803Y0E4
uniprot id: G1N751
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

9103:ITIH2
gene id: 9103:ITIH2
uniprot id: G1MYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9103:GPR17
gene id: 9103:GPR17
uniprot id: G1NRE3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:TMA16
gene id: 9103:TMA16
uniprot id: G1MTF3
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

9103:SLC25A47
gene id: 9103:SLC25A47
uniprot id: A0A803YIJ2
uniprot id: G1NKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:SPAM1
gene id: 9103:SPAM1
uniprot id: G1N8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

9103:NDUFA10
gene id: 9103:NDUFA10
uniprot id: A0A803XS04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

9103:RFTN2
gene id: 9103:RFTN2
uniprot id: G1N5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

9103:NUF2
gene id: 9103:NUF2
uniprot id: A0A803YGD9
names: Similarity
messages: Belongs to the NUF2 family.

9103:GNL2
gene id: 9103:GNL2
uniprot id: G1MW94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

9103:IL1RL1
gene id: 9103:IL1RL1
uniprot id: G1NPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

9103:RAB29
gene id: 9103:RAB29
uniprot id: A0A803YR46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9103:SEMA3E
gene id: 9103:SEMA3E
uniprot id: G1N1I1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:HOXB1
gene id: 9103:HOXB1
uniprot id: H9H0F2
names: Subcellular Location Annotation
messages: Nucleus

9103:FBLN5
gene id: 9103:FBLN5
uniprot id: G1NKA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ADCY3
gene id: 9103:ADCY3
uniprot id: A0A803XN19
uniprot id: G1NMX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9103:CHGA
gene id: 9103:CHGA
uniprot id: A0A803Y422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9103:CAMTA1
gene id: 9103:CAMTA1
uniprot id: A0A803XX96
uniprot id: A0A803Y0F6
uniprot id: G1MQR7
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

9103:IL2RB
gene id: 9103:IL2RB
uniprot id: G1NJ37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

9103:FGF18
gene id: 9103:FGF18
uniprot id: G1MS24
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9103:LOC100548974
gene id: 9103:LOC100548974
uniprot id: A0A803Y911
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9103:SPOUT1
gene id: 9103:SPOUT1
uniprot id: G1MZD7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

9103:SKIL
gene id: 9103:SKIL
uniprot id: G1NCS6
names: Similarity
messages: Belongs to the SKI family.

9103:CTLA4
gene id: 9103:CTLA4
uniprot id: G1N9D2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

9103:ACAD11
gene id: 9103:ACAD11
uniprot id: A0A803YB95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9103:LOC100550565
gene id: 9103:LOC100550565
uniprot id: G1MPT1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

9103:GTF3C5
gene id: 9103:GTF3C5
uniprot id: G1N3C9
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100546964
gene id: 9103:LOC100546964
uniprot id: G1N1K0
names: Similarity
messages: Belongs to the PrpD family.

9103:LOC100541174
gene id: 9103:LOC100541174
uniprot id: G1NCM4
names: Subcellular Location Annotation
messages: Membrane

9103:TSHR
gene id: 9103:TSHR
uniprot id: G1NJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

9103:CHMP1B
gene id: 9103:CHMP1B
uniprot id: G1MSD9
names: Similarity
messages: Belongs to the SNF7 family.

9103:LOC104912421
gene id: 9103:LOC104912421
uniprot id: A0A803XNQ0
names: Similarity
messages: Belongs to the DOCK family.

9103:USP2
gene id: 9103:USP2
uniprot id: G1MU74
names: Similarity
messages: Belongs to the peptidase C19 family.

9103:BCL9
gene id: 9103:BCL9
uniprot id: G1NNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9103:VPS26B
gene id: 9103:VPS26B
uniprot id: G1MS48
names: Similarity
messages: Belongs to the VPS26 family.

9103:ING4
gene id: 9103:ING4
uniprot id: G1NMT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9103:LOC100543567
gene id: 9103:LOC100543567
uniprot id: A0A803YAU4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

9103:LOC100550809
gene id: 9103:LOC100550809
uniprot id: G1NE03
names: Similarity
messages: Belongs to the amidase family.

9103:POLR2J
gene id: 9103:POLR2J
uniprot id: G1MWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

9103:LOC100546568
gene id: 9103:LOC100546568
uniprot id: A0A803YCB7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LGR6
gene id: 9103:LGR6
uniprot id: G1MR85
names: Subcellular Location Annotation
messages: Membrane

9103:MRPS9
gene id: 9103:MRPS9
uniprot id: A0A803Y0F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS9 family.
messages: Nucleus

9103:LOXL2
gene id: 9103:LOXL2
uniprot id: G1MRH0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9103:SIRT4
gene id: 9103:SIRT4
uniprot id: G1N9J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

9103:GPRC5B
gene id: 9103:GPRC5B
uniprot id: G1NC23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:DDX1
gene id: 9103:DDX1
uniprot id: G1NML8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

9103:GPX8
gene id: 9103:GPX8
uniprot id: A0A803YS38
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9103:NCBP2
gene id: 9103:NCBP2
uniprot id: A0A803YQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

9103:ACOD1
gene id: 9103:ACOD1
uniprot id: G1NPY9
names: Similarity
messages: Belongs to the PrpD family.

9103:VOPP1
gene id: 9103:VOPP1
uniprot id: A0A803XRJ7
uniprot id: A0A803YCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9103:TNC
gene id: 9103:TNC
uniprot id: A0A803XY97
uniprot id: A0A803YGC0
uniprot id: A0A803YK94
uniprot id: G1MVR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9103:GATA5
gene id: 9103:GATA5
uniprot id: G1N277
names: Subcellular Location Annotation
messages: Nucleus

9103:DOLPP1
gene id: 9103:DOLPP1
uniprot id: G1N041
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

9103:PPP6R3
gene id: 9103:PPP6R3
uniprot id: G1NAS9
names: Similarity
messages: Belongs to the SAPS family.

9103:KMT2C
gene id: 9103:KMT2C
uniprot id: A0A803XUG8
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100548433
gene id: 9103:LOC100548433
uniprot id: G1NN74
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:EGFR
gene id: 9103:EGFR
uniprot id: G3UQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

9103:C1R
gene id: 9103:C1R
uniprot id: G3UP05
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TOP3B
gene id: 9103:TOP3B
uniprot id: A0A803YR67
uniprot id: G1MQQ8
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

9103:TCP11L1
gene id: 9103:TCP11L1
uniprot id: G1MRE9
names: Similarity
messages: Belongs to the TCP11 family.

9103:DDX49
gene id: 9103:DDX49
uniprot id: G3URB9
names: Similarity
messages: Belongs to the DEAD box helicase family.

9103:HSP90B1
gene id: 9103:HSP90B1
uniprot id: G1NK19
names: Similarity
messages: Belongs to the heat shock protein 90 family.

9103:LOC100544807
gene id: 9103:LOC100544807
uniprot id: G3USQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9103:FKTN
gene id: 9103:FKTN
uniprot id: G1N6X1
names: Similarity
messages: Belongs to the LicD transferase family.

9103:DNAJA1
gene id: 9103:DNAJA1
uniprot id: G1N266
names: Subcellular Location Annotation
messages: Membrane

9103:PROS1
gene id: 9103:PROS1
uniprot id: G1NNL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:RNF168
gene id: 9103:RNF168
uniprot id: G1MW43
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF168 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

9103:FBXO32
gene id: 9103:FBXO32
uniprot id: G1NJ13
names: Subcellular Location Annotation
messages: Nucleus

9103:ANO9
gene id: 9103:ANO9
uniprot id: G1MUT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NTHL1
gene id: 9103:NTHL1
uniprot id: G1N2F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

9103:LRWD1
gene id: 9103:LRWD1
uniprot id: G1MWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

9103:COL4A2
gene id: 9103:COL4A2
uniprot id: G1NPT0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9103:CTSS
gene id: 9103:CTSS
uniprot id: G1MQG9
names: Similarity
messages: Belongs to the peptidase C1 family.

9103:ELOVL5
gene id: 9103:ELOVL5
uniprot id: D4N2R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

9103:NSUN3
gene id: 9103:NSUN3
uniprot id: G1NNM1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9103:TPT1
gene id: 9103:TPT1
uniprot id: G1NQ36
names: Similarity
messages: Belongs to the TCTP family.

9103:IL17B
gene id: 9103:IL17B
uniprot id: A0A803XQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9103:LOC100547702
gene id: 9103:LOC100547702
uniprot id: G1MZW3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9103:LOC100544984
gene id: 9103:LOC100544984
uniprot id: G1MU85
names: Similarity
messages: Belongs to the perilipin family.

9103:SMC6
gene id: 9103:SMC6
uniprot id: G1NMM3
names: Subcellular Location Annotation
messages: Chromosome

9103:APRT
gene id: 9103:APRT
uniprot id: G1N6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

9103:LOC100542671
gene id: 9103:LOC100542671
uniprot id: G1NPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

9103:DDX47
gene id: 9103:DDX47
uniprot id: G1NH23
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

9103:UCKL1
gene id: 9103:UCKL1
uniprot id: A0A803Y1X3
uniprot id: A0A803Y3S2
names: Similarity
messages: Belongs to the uridine kinase family.

9103:SGTA
gene id: 9103:SGTA
uniprot id: G1MYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SGT family.
messages: Cytoplasm

9103:KITLG
gene id: 9103:KITLG
uniprot id: G1NFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Homodimer, non-covalently linked.
messages: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Secreted
messages: filopodium
messages: lamellipodium

9103:N6AMT1
gene id: 9103:N6AMT1
uniprot id: G1NNU4
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

9103:MAFG
gene id: 9103:MAFG
uniprot id: A0A803YD60
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9103:ARSI
gene id: 9103:ARSI
uniprot id: G1N451
names: Similarity
messages: Belongs to the sulfatase family.

9103:ASPA
gene id: 9103:ASPA
uniprot id: A0A803YJA4
uniprot id: G1N4L9
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

9103:FAM110D
gene id: 9103:FAM110D
uniprot id: G1MUF3
names: Similarity
messages: Belongs to the FAM110 family.

9103:P2RY4
gene id: 9103:P2RY4
uniprot id: G1NRN1
uniprot id: O57466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:GRB10
gene id: 9103:GRB10
uniprot id: A0A803XMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

9103:ADAMTS17
gene id: 9103:ADAMTS17
uniprot id: G3UPV2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ST7
gene id: 9103:ST7
uniprot id: A0A803YSG9
uniprot id: G1N9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9103:NMUR2
gene id: 9103:NMUR2
uniprot id: G1N2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

9103:CD40LG
gene id: 9103:CD40LG
uniprot id: A0A803Y1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

9103:SEPTIN11
gene id: 9103:SEPTIN11
uniprot id: G1NAY8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9103:LOC100549241
gene id: 9103:LOC100549241
uniprot id: G1MZ80
names: Similarity
messages: Belongs to the TPPP family.

9103:KCNJ4
gene id: 9103:KCNJ4
uniprot id: G1NIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9103:HOPX
gene id: 9103:HOPX
uniprot id: G1N8X9
names: Subcellular Location Annotation
messages: Nucleus

9103:ADA2
gene id: 9103:ADA2
uniprot id: G1NL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

9103:SEMA3C
gene id: 9103:SEMA3C
uniprot id: G1N265
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:HTR6
gene id: 9103:HTR6
uniprot id: G1N1I6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:LOC100551038
gene id: 9103:LOC100551038
uniprot id: A0A803XWR3
uniprot id: G1NP20
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

9103:PFN4
gene id: 9103:PFN4
uniprot id: G1NMP9
names: Similarity
messages: Belongs to the profilin family.

9103:ID2
gene id: 9103:ID2
uniprot id: G1NMI0
names: Subcellular Location Annotation
messages: Nucleus

9103:NUP205
gene id: 9103:NUP205
uniprot id: G1NGU0
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

9103:SLU7
gene id: 9103:SLU7
uniprot id: G1MV97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9103:CLDN2
gene id: 9103:CLDN2
uniprot id: G1N0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9103:SLCO4C1
gene id: 9103:SLCO4C1
uniprot id: A0A803XTC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NUSAP1
gene id: 9103:NUSAP1
uniprot id: G1NFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

9103:SOST
gene id: 9103:SOST
uniprot id: A0A803YRN3
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CLIC5
gene id: 9103:CLIC5
uniprot id: A0A803XS45
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9103:KCNJ8
gene id: 9103:KCNJ8
uniprot id: G1NLM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9103:P2RY8
gene id: 9103:P2RY8
uniprot id: G1NPG4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:PPM1A
gene id: 9103:PPM1A
uniprot id: G1NLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

9103:BEND6
gene id: 9103:BEND6
uniprot id: G1NM92
names: Subcellular Location Annotation
messages: Nucleus

9103:RARB
gene id: 9103:RARB
uniprot id: G1NEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9103:TUBGCP2
gene id: 9103:TUBGCP2
uniprot id: G1MST2
uniprot id: G3UTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9103:SYNJ2
gene id: 9103:SYNJ2
uniprot id: G1NJM1
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

9103:MYCBP
gene id: 9103:MYCBP
uniprot id: G1MV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

9103:TINAG
gene id: 9103:TINAG
uniprot id: G1NMB6
names: Similarity
messages: Belongs to the peptidase C1 family.

9103:EIF2S1
gene id: 9103:EIF2S1
uniprot id: G1NHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

9103:NAPG
gene id: 9103:NAPG
uniprot id: G1N9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9103:CISD2
gene id: 9103:CISD2
uniprot id: G1NFR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

9103:DLL1
gene id: 9103:DLL1
uniprot id: G1NHX8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9103:PTPN11
gene id: 9103:PTPN11
uniprot id: G1N245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

9103:P2RX1
gene id: 9103:P2RX1
uniprot id: G1MVE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9103:MARK3
gene id: 9103:MARK3
uniprot id: A0A803XTY3
uniprot id: A0A803Y3B9
uniprot id: A0A803YFU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9103:RIN3
gene id: 9103:RIN3
uniprot id: G1NKC4
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

9103:OTOP2
gene id: 9103:OTOP2
uniprot id: G1NAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9103:LOC100550717
gene id: 9103:LOC100550717
uniprot id: A0A803YKP7
uniprot id: G1MU12
names: Subcellular Location Annotation
messages: Nucleus

9103:SLA
gene id: 9103:SLA
uniprot id: G1NJM3
names: Subcellular Location Annotation
messages: Cytoplasm

9103:ALDH1A3
gene id: 9103:ALDH1A3
uniprot id: G1NAV4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9103:TCTE3
gene id: 9103:TCTE3
uniprot id: G1NHZ0
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9103:CLUL1
gene id: 9103:CLUL1
uniprot id: G1NBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

9103:CASQ2
gene id: 9103:CASQ2
uniprot id: G1NNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

9103:PLD1
gene id: 9103:PLD1
uniprot id: A0A803Y0T4
names: Similarity
messages: Belongs to the phospholipase D family.

9103:ABCB5
gene id: 9103:ABCB5
uniprot id: G1ND57
names: Subcellular Location Annotation
messages: Membrane

9103:TRADD
gene id: 9103:TRADD
uniprot id: A0A803XSX1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:DUSP6
gene id: 9103:DUSP6
uniprot id: G1NFD8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9103:PPP4R3B
gene id: 9103:PPP4R3B
uniprot id: G1MT71
names: Similarity
messages: Belongs to the SMEK family.

9103:IRF6
gene id: 9103:IRF6
uniprot id: G1MZ34
names: Subcellular Location Annotation
messages: Nucleus

9103:TPH2
gene id: 9103:TPH2
uniprot id: G1NE85
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9103:LOC100550794
gene id: 9103:LOC100550794
uniprot id: A0A803YJQ5
names: Similarity
messages: Belongs to the TMEM14 family.

9103:B3GNT2
gene id: 9103:B3GNT2
uniprot id: G1NRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:GMDS
gene id: 9103:GMDS
uniprot id: A0A803XY18
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

9103:REXO2
gene id: 9103:REXO2
uniprot id: G1MVK1
names: Similarity
messages: Belongs to the oligoribonuclease family.

9103:LOC100548691
gene id: 9103:LOC100548691
uniprot id: G1NMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.

9103:SLC25A22
gene id: 9103:SLC25A22
uniprot id: G1NA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:BRS3
gene id: 9103:BRS3
uniprot id: G1MWV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

9103:ADAMTS12
gene id: 9103:ADAMTS12
uniprot id: A0A803XXJ5
uniprot id: A0A803Y2G6
uniprot id: G1NR24
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9103:IL12A
gene id: 9103:IL12A
uniprot id: G1NDR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

9103:CENPO
gene id: 9103:CENPO
uniprot id: G1NMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

9103:LOC100540763
gene id: 9103:LOC100540763
uniprot id: G1MXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

9103:TRPC1
gene id: 9103:TRPC1
uniprot id: G1N410
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

9103:CCDC126
gene id: 9103:CCDC126
uniprot id: A0A803XRK2
names: Subcellular Location Annotation
messages: Secreted

9103:DRD1
gene id: 9103:DRD1
uniprot id: G1NR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:RPL7
gene id: 9103:RPL7
uniprot id: G1NG55
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9103:CACNG4
gene id: 9103:CACNG4
uniprot id: G1N644
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

9103:SLC10A2
gene id: 9103:SLC10A2
uniprot id: G1NPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9103:MFSD8
gene id: 9103:MFSD8
uniprot id: G1MZT7
names: Subcellular Location Annotation
messages: Membrane

9103:CD8B
gene id: 9103:CD8B
uniprot id: A0A803YNH9
names: Subcellular Location Annotation
messages: Membrane

9103:THRB
gene id: 9103:THRB
uniprot id: G1NEU6
uniprot id: G1NEW5
uniprot id: G3UR60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

9103:PRICKLE2
gene id: 9103:PRICKLE2
uniprot id: A0A803Y6L2
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9103:GPC1
gene id: 9103:GPC1
uniprot id: Q6QA54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

9103:NR2C1
gene id: 9103:NR2C1
uniprot id: A0A803YP82
uniprot id: G1NFV2
uniprot id: G3UR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9103:TMOD1
gene id: 9103:TMOD1
uniprot id: G3UTY3
names: Subcellular Location Annotation
messages: cytoskeleton

9103:COPG2
gene id: 9103:COPG2
uniprot id: G1MW97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9103:MCOLN2
gene id: 9103:MCOLN2
uniprot id: G1N9Z2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9103:LOC100549737
gene id: 9103:LOC100549737
uniprot id: G1NRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9103:LOC104910030
gene id: 9103:LOC104910030
uniprot id: G3X8P0
names: Similarity
messages: Belongs to the peptidase M14 family.

9103:LOC100550128
gene id: 9103:LOC100550128
uniprot id: G1NGJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

9103:MMD
gene id: 9103:MMD
uniprot id: A0A803YK29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9103:PITHD1
gene id: 9103:PITHD1
uniprot id: A0A803Y9W5
names: Similarity
messages: Belongs to the PITHD1 family.

9103:GHITM
gene id: 9103:GHITM
uniprot id: G3URU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9103:SGTB
gene id: 9103:SGTB
uniprot id: A0A803XUZ1
names: Similarity
messages: Belongs to the SGT family.

9103:PPIP5K2
gene id: 9103:PPIP5K2
uniprot id: A0A803YIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9103:ABCG2
gene id: 9103:ABCG2
uniprot id: G1N6J2
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100549470
gene id: 9103:LOC100549470
uniprot id: G1N1N0
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

9103:LOC100544081
gene id: 9103:LOC100544081
uniprot id: G1MXM2
names: Similarity
messages: Belongs to the NLRP family.

9103:ADRA1D
gene id: 9103:ADRA1D
uniprot id: G1NKI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

9103:LPAR5
gene id: 9103:LPAR5
uniprot id: G1NMT1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:PNPLA4
gene id: 9103:PNPLA4
uniprot id: G1NPF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ACTA1
gene id: 9103:ACTA1
uniprot id: G1NHJ8
names: Similarity
messages: Belongs to the actin family.

9103:TWF2
gene id: 9103:TWF2
uniprot id: G1MWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

9103:L3MBTL1
gene id: 9103:L3MBTL1
uniprot id: G1MQ87
names: Subcellular Location Annotation
messages: Nucleus

9103:DBH
gene id: 9103:DBH
uniprot id: G1N4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Conversion of dopamine to noradrenaline.
messages: Homotetramer; composed of two disulfide-linked dimers.
messages: chromaffin granule lumen
messages: chromaffin granule membrane
messages: secretory vesicle lumen
messages: secretory vesicle membrane

9103:BRINP2
gene id: 9103:BRINP2
uniprot id: G1MU49
names: Similarity
messages: Belongs to the BRINP family.

9103:NDE1
gene id: 9103:NDE1
uniprot id: G1N592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

9103:DCSTAMP
gene id: 9103:DCSTAMP
uniprot id: G1NID4
names: Subcellular Location Annotation
messages: Membrane

9103:CEP44
gene id: 9103:CEP44
uniprot id: G1N504
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

9103:MLLT11
gene id: 9103:MLLT11
uniprot id: A0A803YIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

9103:CALCA
gene id: 9103:CALCA
uniprot id: G1N4N0
names: Similarity
messages: Belongs to the calcitonin family.

9103:GHSR
gene id: 9103:GHSR
uniprot id: G1NCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:NDUFB10
gene id: 9103:NDUFB10
uniprot id: G1N1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

9103:PTCH2
gene id: 9103:PTCH2
uniprot id: G1NCW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9103:NFYB
gene id: 9103:NFYB
uniprot id: G1NJX0
uniprot id: G3UPA1
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

9103:FAIM2
gene id: 9103:FAIM2
uniprot id: G1NF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9103:OPRL1
gene id: 9103:OPRL1
uniprot id: A0A803YSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

9103:SNF8
gene id: 9103:SNF8
uniprot id: G1N5F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

9103:PIK3CA
gene id: 9103:PIK3CA
uniprot id: G1NC03
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9103:LOC678666
gene id: 9103:LOC678666
uniprot id: O93380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

9103:PPM1E
gene id: 9103:PPM1E
uniprot id: G1N5H1
names: Similarity
messages: Belongs to the PP2C family.

9103:TMEM138
gene id: 9103:TMEM138
uniprot id: G1N056
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

9103:PACSIN1
gene id: 9103:PACSIN1
uniprot id: H9H0G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

9103:DISP3
gene id: 9103:DISP3
uniprot id: A0A803Y6P8
uniprot id: G1N3U1
names: Subcellular Location Annotation
messages: Membrane

9103:ADD3
gene id: 9103:ADD3
uniprot id: G1NE42
uniprot id: G5E7P1
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9103:CENPN
gene id: 9103:CENPN
uniprot id: A0A803YFN2
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

9103:LOC100546220
gene id: 9103:LOC100546220
uniprot id: G1N3F2
names: Similarity
messages: Belongs to the peptidase A1 family.

9103:RHBDF2
gene id: 9103:RHBDF2
uniprot id: G1MYF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

9103:SEC24D
gene id: 9103:SEC24D
uniprot id: G1NE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9103:UGT8
gene id: 9103:UGT8
uniprot id: G1NEF8
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

9103:IL4I1
gene id: 9103:IL4I1
uniprot id: B1N1B4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9103:EXOSC9
gene id: 9103:EXOSC9
uniprot id: G1NDW4
names: Subcellular Location Annotation
messages: Cytoplasm

9103:EMC3
gene id: 9103:EMC3
uniprot id: G1MU78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

9103:PIGC
gene id: 9103:PIGC
uniprot id: A0A803YAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

9103:DGKD
gene id: 9103:DGKD
uniprot id: G1MS39
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9103:GNG4
gene id: 9103:GNG4
uniprot id: G1NH37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9103:EIF3E
gene id: 9103:EIF3E
uniprot id: G1NIH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

9103:TPRG1L
gene id: 9103:TPRG1L
uniprot id: G1MSG5
names: Similarity
messages: Belongs to the TPRG1 family.

9103:MAPK9
gene id: 9103:MAPK9
uniprot id: G1N6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9103:ST6GALNAC4
gene id: 9103:ST6GALNAC4
uniprot id: G1MX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:NME8
gene id: 9103:NME8
uniprot id: A0A803YGM5
names: Similarity
messages: Belongs to the NDK family.

9103:MRTO4
gene id: 9103:MRTO4
uniprot id: G1N1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

9103:LOC100545607
gene id: 9103:LOC100545607
uniprot id: G1N363
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

9103:TMCC3
gene id: 9103:TMCC3
uniprot id: A0A803XSY4
uniprot id: A0A803YJD3
names: Similarity
messages: Belongs to the TEX28 family.

9103:LOC100538434
gene id: 9103:LOC100538434
uniprot id: G1NE81
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:AGTRAP
gene id: 9103:AGTRAP
uniprot id: G1N3K8
names: Subcellular Location Annotation
messages: Membrane

9103:ZP1
gene id: 9103:ZP1
uniprot id: Q25BN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:MIEF1
gene id: 9103:MIEF1
uniprot id: G1NIF1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9103:LIG3
gene id: 9103:LIG3
uniprot id: G1MY77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9103:MDFIC
gene id: 9103:MDFIC
uniprot id: G1N9V9
names: Similarity
messages: Belongs to the MDFI family.

9103:LPAR4
gene id: 9103:LPAR4
uniprot id: G1NRN7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:STAT3
gene id: 9103:STAT3
uniprot id: G1MWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9103:DUSP27
gene id: 9103:DUSP27
uniprot id: G1NNP2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9103:LOC100543299
gene id: 9103:LOC100543299
uniprot id: G1NDF8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

9103:NIPA2
gene id: 9103:NIPA2
uniprot id: G1NPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9103:PKNOX1
gene id: 9103:PKNOX1
uniprot id: G1NP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9103:UNC5B
gene id: 9103:UNC5B
uniprot id: G3UUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9103:GJB1
gene id: 9103:GJB1
uniprot id: G1NSA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9103:NAGA
gene id: 9103:NAGA
uniprot id: G1NHI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

9103:PTGR1
gene id: 9103:PTGR1
uniprot id: G1N927
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

9103:SLC25A15
gene id: 9103:SLC25A15
uniprot id: G1NQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:CTBP2
gene id: 9103:CTBP2
uniprot id: G1NGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

9103:SERPINF1
gene id: 9103:SERPINF1
uniprot id: G1N131
names: Similarity
messages: Belongs to the serpin family.

9103:RHBDD2
gene id: 9103:RHBDD2
uniprot id: G1MXJ8
names: Subcellular Location Annotation
messages: Membrane

9103:NDP
gene id: 9103:NDP
uniprot id: G1NP39
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:WASHC1
gene id: 9103:WASHC1
uniprot id: A0A803XLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

9103:LOC100542307
gene id: 9103:LOC100542307
uniprot id: G1NME1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

9103:LOC100548588
gene id: 9103:LOC100548588
uniprot id: A0A803XLR1
uniprot id: A0A803XWR9
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:PTTG1
gene id: 9103:PTTG1
uniprot id: A0A803XXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

9103:NKX2-8
gene id: 9103:NKX2-8
uniprot id: G1NIS9
names: Subcellular Location Annotation
messages: Nucleus

9103:IST1
gene id: 9103:IST1
uniprot id: G1N9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

9103:C1H11orf54
gene id: 9103:C1H11orf54
uniprot id: G1NQN3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9103:LOC100540299
gene id: 9103:LOC100540299
uniprot id: A0A803YRL7
uniprot id: G1N455
names: Subcellular Location Annotation
messages: Membrane

9103:ELP3
gene id: 9103:ELP3
uniprot id: G1NN03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

9103:TNFRSF19
gene id: 9103:TNFRSF19
uniprot id: G1NQE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100548108
gene id: 9103:LOC100548108
uniprot id: G1MSQ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9103:CPO
gene id: 9103:CPO
uniprot id: G1N8J1
names: Similarity
messages: Belongs to the peptidase M14 family.

9103:ARPC3
gene id: 9103:ARPC3
uniprot id: G1MXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

9103:RRN3
gene id: 9103:RRN3
uniprot id: G3UQA6
names: Similarity
messages: Belongs to the RRN3 family.

9103:CMTR1
gene id: 9103:CMTR1
uniprot id: G1NE56
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

9103:PLN
gene id: 9103:PLN
uniprot id: A0A803XW87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

9103:TIPARP
gene id: 9103:TIPARP
uniprot id: G1NE06
names: Similarity
messages: Belongs to the ARTD/PARP family.

9103:ESCO1
gene id: 9103:ESCO1
uniprot id: G1NC62
names: Subcellular Location Annotation
messages: Nucleus

9103:CYTB
gene id: 9103:CYTB
uniprot id: P50663
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

9103:LOC100539381
gene id: 9103:LOC100539381
uniprot id: G1MT01
names: Similarity
messages: Belongs to the avidin/streptavidin family.

9103:MAP2K3
gene id: 9103:MAP2K3
uniprot id: G1MYN0
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:NATD1
gene id: 9103:NATD1
uniprot id: G1MYJ9
names: Similarity
messages: Belongs to the NATD1 family.

9103:LOC104917567
gene id: 9103:LOC104917567
uniprot id: G1NQ90
names: Subcellular Location Annotation
messages: Membrane

9103:CEP76
gene id: 9103:CEP76
uniprot id: A0A803XXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

9103:PALM
gene id: 9103:PALM
uniprot id: G1MWL4
names: Similarity
messages: Belongs to the paralemmin family.

9103:SAMD4A
gene id: 9103:SAMD4A
uniprot id: A0A803YCS5
uniprot id: G1NLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

9103:LAMB3
gene id: 9103:LAMB3
uniprot id: G1MYW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CCDC93
gene id: 9103:CCDC93
uniprot id: G1NIB2
names: Similarity
messages: Belongs to the CCDC93 family.

9103:LOC100542794
gene id: 9103:LOC100542794
uniprot id: G1MZ15
names: Similarity
messages: Belongs to the hexokinase family.

9103:TSEN2
gene id: 9103:TSEN2
uniprot id: G1N0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

9103:RPS21
gene id: 9103:RPS21
uniprot id: G1N222
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

9103:SNRPC
gene id: 9103:SNRPC
uniprot id: G1N2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

9103:BOK
gene id: 9103:BOK
uniprot id: G1MWK7
names: Similarity
messages: Belongs to the Bcl-2 family.

9103:TH
gene id: 9103:TH
uniprot id: G1N7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

9103:LAMTOR5
gene id: 9103:LAMTOR5
uniprot id: G1MTY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

9103:LZIC
gene id: 9103:LZIC
uniprot id: G1MY71
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9103:EEF1B2
gene id: 9103:EEF1B2
uniprot id: G1N8V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

9103:LOC100303673
gene id: 9103:LOC100303673
uniprot id: Q6J9X5
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC104914182
gene id: 9103:LOC104914182
uniprot id: G1N3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

9103:TMEM182
gene id: 9103:TMEM182
uniprot id: G1NPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

9103:ITGB1
gene id: 9103:ITGB1
uniprot id: A0A803XLR5
uniprot id: G1N3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

9103:HOMER2
gene id: 9103:HOMER2
uniprot id: G1N6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9103:ODF2
gene id: 9103:ODF2
uniprot id: G1MYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9103:LOC100540209
gene id: 9103:LOC100540209
uniprot id: G1NP38
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9103:RNF4
gene id: 9103:RNF4
uniprot id: A0A803YIP9
names: Subcellular Location Annotation
messages: Nucleus

9103:CEP19
gene id: 9103:CEP19
uniprot id: G1MW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

9103:MIOS
gene id: 9103:MIOS
uniprot id: G1NBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

9103:NFKB1
gene id: 9103:NFKB1
uniprot id: G1NFM9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:SLX4
gene id: 9103:SLX4
uniprot id: G1NAH3
names: Similarity
messages: Belongs to the SLX4 family.

9103:RTRAF
gene id: 9103:RTRAF
uniprot id: G1NLZ3
names: Similarity
messages: Belongs to the RTRAF family.

9103:SCD
gene id: 9103:SCD
uniprot id: G1N6B0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9103:YWHAB
gene id: 9103:YWHAB
uniprot id: G1MXY2
names: Similarity
messages: Belongs to the 14-3-3 family.

9103:MRAP
gene id: 9103:MRAP
uniprot id: A0A803YLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:MYO1F
gene id: 9103:MYO1F
uniprot id: G1MSJ5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:SGMS2
gene id: 9103:SGMS2
uniprot id: G1N2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9103:SEC24C
gene id: 9103:SEC24C
uniprot id: A0A803XM24
uniprot id: G1N450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9103:LOC100541373
gene id: 9103:LOC100541373
uniprot id: G1NR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

9103:UGDH
gene id: 9103:UGDH
uniprot id: G1NI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

9103:ACSL6
gene id: 9103:ACSL6
uniprot id: G1N9D1
uniprot id: G3UQP1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

9103:SPIN1
gene id: 9103:SPIN1
uniprot id: G1MUA7
names: Similarity
messages: Belongs to the SPIN/STSY family.

9103:SDF4
gene id: 9103:SDF4
uniprot id: G1MW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

9103:PAN3
gene id: 9103:PAN3
uniprot id: G1NQC7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

9103:RAG1
gene id: 9103:RAG1
uniprot id: G1NRN5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

9103:TSPAN12
gene id: 9103:TSPAN12
uniprot id: G1N996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9103:LOC104913713
gene id: 9103:LOC104913713
uniprot id: A0A803Y874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:UBA52
gene id: 9103:UBA52
uniprot id: A0A803Y4P4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

9103:PCBD1
gene id: 9103:PCBD1
uniprot id: G1N0R5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

9103:BCLAF1
gene id: 9103:BCLAF1
uniprot id: A0A803XM89
uniprot id: A0A803YHG7
uniprot id: G1NK36
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9103:TBXA2R
gene id: 9103:TBXA2R
uniprot id: G1NRK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:EAF1
gene id: 9103:EAF1
uniprot id: G1NFN0
names: Similarity
messages: Belongs to the EAF family.

9103:PREP
gene id: 9103:PREP
uniprot id: G1NLB6
names: Similarity
messages: Belongs to the peptidase S9A family.

9103:LOC100542122
gene id: 9103:LOC100542122
uniprot id: A0A803YAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

9103:KLHL40
gene id: 9103:KLHL40
uniprot id: G1MU07
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

9103:ST14
gene id: 9103:ST14
uniprot id: G1MR46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:LOC100550262
gene id: 9103:LOC100550262
uniprot id: G1MUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9103:CLRN3
gene id: 9103:CLRN3
uniprot id: G1NGV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9103:CLN8
gene id: 9103:CLN8
uniprot id: G1NMF5
names: Subcellular Location Annotation
messages: Membrane

9103:BEST3
gene id: 9103:BEST3
uniprot id: G1NPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

9103:STAM2
gene id: 9103:STAM2
uniprot id: A0A803XP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

9103:ABCB7
gene id: 9103:ABCB7
uniprot id: A0A803YKS7
uniprot id: G1N2U0
names: Subcellular Location Annotation
messages: Membrane

9103:VGLL2
gene id: 9103:VGLL2
uniprot id: A0A803YQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

9103:SF3B3
gene id: 9103:SF3B3
uniprot id: G1MS46
names: Subcellular Location Annotation
messages: Nucleus

9103:PPP1R21
gene id: 9103:PPP1R21
uniprot id: G1N0H7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9103:MRRF
gene id: 9103:MRRF
uniprot id: A0A803YQ57
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

9103:CCKAR
gene id: 9103:CCKAR
uniprot id: G1NIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9103:SNAP23
gene id: 9103:SNAP23
uniprot id: G1NG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

9103:SMG7
gene id: 9103:SMG7
uniprot id: A0A803YP42
uniprot id: G1MS66
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

9103:SLC17A6
gene id: 9103:SLC17A6
uniprot id: G1MT63
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100542495
gene id: 9103:LOC100542495
uniprot id: G1MWB0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9103:FAM83H
gene id: 9103:FAM83H
uniprot id: H9H1W5
names: Similarity
messages: Belongs to the FAM83 family.

9103:UBE2H
gene id: 9103:UBE2H
uniprot id: A0A803YN37
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:DRAM2
gene id: 9103:DRAM2
uniprot id: G1N106
names: Subcellular Location Annotation
messages: Membrane

9103:MYOD1
gene id: 9103:MYOD1
uniprot id: Q6DV59
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

9103:CAMKMT
gene id: 9103:CAMKMT
uniprot id: G1NCX3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:LYZ
gene id: 9103:LYZ
uniprot id: P00703
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
messages: Monomer.
messages: Secreted

9103:ZP4
gene id: 9103:ZP4
uniprot id: G1N505
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

9103:BLMH
gene id: 9103:BLMH
uniprot id: G1N312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

9103:PHC3
gene id: 9103:PHC3
uniprot id: G1NCV3
names: Subcellular Location Annotation
messages: Nucleus

9103:GHRH
gene id: 9103:GHRH
uniprot id: G1MTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9103:ZWILCH
gene id: 9103:ZWILCH
uniprot id: G1NBY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

9103:LOC100538956
gene id: 9103:LOC100538956
uniprot id: G1N517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

9103:TBCD
gene id: 9103:TBCD
uniprot id: G1MX06
names: Similarity
messages: Belongs to the TBCD family.

9103:DOK2
gene id: 9103:DOK2
uniprot id: A0A803XWP6
uniprot id: A0A803YK17
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

9103:IFITM5
gene id: 9103:IFITM5
uniprot id: G1MUD2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9103:TIMP2
gene id: 9103:TIMP2
uniprot id: G3UTJ0
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

9103:SSX2IP
gene id: 9103:SSX2IP
uniprot id: G1NA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

9103:RIOK1
gene id: 9103:RIOK1
uniprot id: G1MXN3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9103:PROM1
gene id: 9103:PROM1
uniprot id: A0A803Y301
uniprot id: A0A803Y5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9103:TIMM9
gene id: 9103:TIMM9
uniprot id: G1NLI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9103:TMEM199
gene id: 9103:TMEM199
uniprot id: A0A803YKW5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:GPSM2
gene id: 9103:GPSM2
uniprot id: A0A803Y4Z6
uniprot id: G1N329
names: Similarity
messages: Belongs to the GPSM family.

9103:NTNG2
gene id: 9103:NTNG2
uniprot id: A0A803YPR9
uniprot id: G1N2K8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:IRAK4
gene id: 9103:IRAK4
uniprot id: G1NB62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

9103:LOC100541145
gene id: 9103:LOC100541145
uniprot id: G1NKL1
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

9103:LOC100547680
gene id: 9103:LOC100547680
uniprot id: A0A803XSZ6
names: Similarity
messages: Belongs to the actin family.

9103:SAXO1
gene id: 9103:SAXO1
uniprot id: G1N1Y4
names: Similarity
messages: Belongs to the FAM154 family.

9103:ADD1
gene id: 9103:ADD1
uniprot id: A0A803Y0R2
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9103:LBH
gene id: 9103:LBH
uniprot id: G1N1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

9103:ZEB2
gene id: 9103:ZEB2
uniprot id: G1NJ41
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

9103:SLC25A17
gene id: 9103:SLC25A17
uniprot id: G1NI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:LOC100545752
gene id: 9103:LOC100545752
uniprot id: G1N4Z6
names: Subcellular Location Annotation
messages: Membrane

9103:MARCO
gene id: 9103:MARCO
uniprot id: A0A803YJ71
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:KCNMB2
gene id: 9103:KCNMB2
uniprot id: G1NC17
names: Subcellular Location Annotation
messages: Membrane

9103:ADGRA2
gene id: 9103:ADGRA2
uniprot id: G1MSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9103:CXCL12
gene id: 9103:CXCL12
uniprot id: G1N7W8
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

9103:RBM17
gene id: 9103:RBM17
uniprot id: G1MXX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

9103:MAP3K7
gene id: 9103:MAP3K7
uniprot id: A0A803Y192
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9103:HARS1
gene id: 9103:HARS1
uniprot id: G3UT80
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9103:PLA2G4A
gene id: 9103:PLA2G4A
uniprot id: G1MRF4
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

9103:NDUFA12
gene id: 9103:NDUFA12
uniprot id: A0A803Y9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9103:PROKR1
gene id: 9103:PROKR1
uniprot id: G1MYX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:LOC100546803
gene id: 9103:LOC100546803
uniprot id: G1NS01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9103:RAX2
gene id: 9103:RAX2
uniprot id: G1MQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9103:NIF3L1
gene id: 9103:NIF3L1
uniprot id: G1N6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

9103:MYRFL
gene id: 9103:MYRFL
uniprot id: G1NDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

9103:SUMF2
gene id: 9103:SUMF2
uniprot id: A0A803Y9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9103:LOC100542432
gene id: 9103:LOC100542432
uniprot id: G1NIU0
names: Subunit
messages: Monomer.

9103:DIPK1A
gene id: 9103:DIPK1A
uniprot id: G1N7Q1
names: Similarity
messages: Belongs to the DIPK family.

9103:LPCAT2
gene id: 9103:LPCAT2
uniprot id: G1MYQ2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9103:SLCO4A1
gene id: 9103:SLCO4A1
uniprot id: G3UR85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

9103:TSPAN14
gene id: 9103:TSPAN14
uniprot id: G1MQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9103:CD109
gene id: 9103:CD109
uniprot id: G1NM32
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

9103:LOC100545163
gene id: 9103:LOC100545163
uniprot id: G1NFC6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9103:TEF
gene id: 9103:TEF
uniprot id: G1NI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9103:NAA60
gene id: 9103:NAA60
uniprot id: G1NAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

9103:FGF13
gene id: 9103:FGF13
uniprot id: A0A803YDE1
uniprot id: G1MXH0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9103:DYRK2
gene id: 9103:DYRK2
uniprot id: G1ND88
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9103:CAPN11
gene id: 9103:CAPN11
uniprot id: G1NEF6
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:IFNAR2
gene id: 9103:IFNAR2
uniprot id: A0A803YJ79
uniprot id: G1NNW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

9103:CPEB3
gene id: 9103:CPEB3
uniprot id: A0A803XNN0
names: Similarity
messages: Belongs to the RRM CPEB family.

9103:CELF1
gene id: 9103:CELF1
uniprot id: G1NDV4
names: Similarity
messages: Belongs to the CELF/BRUNOL family.

9103:TPI1
gene id: 9103:TPI1
uniprot id: G1NMV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

9103:NDUFB3
gene id: 9103:NDUFB3
uniprot id: G1N6Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

9103:SCNN1G
gene id: 9103:SCNN1G
uniprot id: G1N4M0
names: Subcellular Location Annotation
messages: Membrane

9103:LOC104910687
gene id: 9103:LOC104910687
uniprot id: G1N5F9
names: Subcellular Location Annotation
messages: Secreted

9103:MED30
gene id: 9103:MED30
uniprot id: G1NIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9103:MFSD14A
gene id: 9103:MFSD14A
uniprot id: G1N5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9103:GSTK1
gene id: 9103:GSTK1
uniprot id: G1NMZ9
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

9103:LOC104912110
gene id: 9103:LOC104912110
uniprot id: G3URH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:C28H6orf89
gene id: 9103:C28H6orf89
uniprot id: G5E7X0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9103:SLC23A2
gene id: 9103:SLC23A2
uniprot id: A0A803YNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

9103:ETFDH
gene id: 9103:ETFDH
uniprot id: A0A803YLK2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

9103:LSM3
gene id: 9103:LSM3
uniprot id: G1N6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9103:ERAL1
gene id: 9103:ERAL1
uniprot id: G1NJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

9103:NXPE3
gene id: 9103:NXPE3
uniprot id: G1NNI7
names: Similarity
messages: Belongs to the NXPE family.

9103:CNDP2
gene id: 9103:CNDP2
uniprot id: G1N7Z4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9103:SNCG
gene id: 9103:SNCG
uniprot id: G1MU41
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

9103:RPP30
gene id: 9103:RPP30
uniprot id: A0A803Y8Q4
uniprot id: G1N8L2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

9103:SLC37A3
gene id: 9103:SLC37A3
uniprot id: G1NKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9103:KCNJ5
gene id: 9103:KCNJ5
uniprot id: G1MQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

9103:HECTD1
gene id: 9103:HECTD1
uniprot id: G1NII1
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

9103:EBAG9
gene id: 9103:EBAG9
uniprot id: G1NII8
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

9103:NFIL3
gene id: 9103:NFIL3
uniprot id: G1NS28
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

9103:LOC100540396
gene id: 9103:LOC100540396
uniprot id: G1N5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

9103:VPS29
gene id: 9103:VPS29
uniprot id: G1N0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

9103:GMFB
gene id: 9103:GMFB
uniprot id: A0A803YQK9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

9103:PUF60
gene id: 9103:PUF60
uniprot id: G1NK67
uniprot id: G3URA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

9103:MAFF
gene id: 9103:MAFF
uniprot id: G1NRW8
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9103:MST1R
gene id: 9103:MST1R
uniprot id: G1MUY8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:ORC3
gene id: 9103:ORC3
uniprot id: G1NLN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

9103:LOC100539041
gene id: 9103:LOC100539041
uniprot id: G5E7U3
names: Similarity
messages: Belongs to the peptidase A1 family.

9103:CD247
gene id: 9103:CD247
uniprot id: G1NNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

9103:LOC104910121
gene id: 9103:LOC104910121
uniprot id: G1MYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9103:ADRA2C
gene id: 9103:ADRA2C
uniprot id: G1NRL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:PRDM10
gene id: 9103:PRDM10
uniprot id: A0A803XUQ4
uniprot id: A0A803XV35
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9103:ABCC2
gene id: 9103:ABCC2
uniprot id: G1NB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9103:LOC100541319
gene id: 9103:LOC100541319
uniprot id: A0A803YMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9103:LRP6
gene id: 9103:LRP6
uniprot id: G1NM61
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:PSEN2
gene id: 9103:PSEN2
uniprot id: G1N2Q5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

9103:CSNK1D
gene id: 9103:CSNK1D
uniprot id: A0A803YS01
uniprot id: G1N1Q3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:DCLRE1C
gene id: 9103:DCLRE1C
uniprot id: G3UPF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9103:GNG2
gene id: 9103:GNG2
uniprot id: G1NLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9103:CRAT
gene id: 9103:CRAT
uniprot id: G1N094
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9103:HADHB
gene id: 9103:HADHB
uniprot id: G1NMT3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9103:EIF4ENIF1
gene id: 9103:EIF4ENIF1
uniprot id: G1N8G8
names: Subcellular Location Annotation
messages: Cytoplasm

9103:NHS
gene id: 9103:NHS
uniprot id: G1NPA8
names: Similarity
messages: Belongs to the NHS family.

9103:HDAC10
gene id: 9103:HDAC10
uniprot id: G1N7M5
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

9103:ZNF706
gene id: 9103:ZNF706
uniprot id: A0A803XW74
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:LETM2
gene id: 9103:LETM2
uniprot id: G1MT37
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

9103:TMED2
gene id: 9103:TMED2
uniprot id: A0A803YG99
uniprot id: A0A803YJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9103:PAX6
gene id: 9103:PAX6
uniprot id: G1MS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9103:PLIN1
gene id: 9103:PLIN1
uniprot id: G1N8E6
names: Similarity
messages: Belongs to the perilipin family.

9103:NIPAL3
gene id: 9103:NIPAL3
uniprot id: G1N2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9103:IKBKB
gene id: 9103:IKBKB
uniprot id: G1MVF3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:LOC100545462
gene id: 9103:LOC100545462
uniprot id: G1MWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9103:LIN28B
gene id: 9103:LIN28B
uniprot id: A0A803YFQ5
uniprot id: G1NLB9
names: Similarity
messages: Belongs to the lin-28 family.

9103:ANO10
gene id: 9103:ANO10
uniprot id: A0A803XRT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NEIL3
gene id: 9103:NEIL3
uniprot id: G1N4K2
names: Similarity
messages: Belongs to the FPG family.

9103:CZIB
gene id: 9103:CZIB
uniprot id: G1NFI6
names: Similarity
messages: Belongs to the UPF0587 family.

9103:CDH2
gene id: 9103:CDH2
uniprot id: G1NDC6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9103:LPL
gene id: 9103:LPL
uniprot id: G3UPD5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

9103:HNRNPA3
gene id: 9103:HNRNPA3
uniprot id: G1NBB9
names: Subcellular Location Annotation
messages: Nucleus

9103:TXNL4A
gene id: 9103:TXNL4A
uniprot id: G1MTF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

9103:SLC45A1
gene id: 9103:SLC45A1
uniprot id: G1MQD4
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100541604
gene id: 9103:LOC100541604
uniprot id: G3UPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:PRR5L
gene id: 9103:PRR5L
uniprot id: A0A803XUF9
names: Similarity
messages: Belongs to the PROTOR family.

9103:CALHM6
gene id: 9103:CALHM6
uniprot id: G1NKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9103:SLC16A14
gene id: 9103:SLC16A14
uniprot id: G1N2V9
names: Subcellular Location Annotation
messages: Membrane

9103:BBS5
gene id: 9103:BBS5
uniprot id: A0A803YFB2
uniprot id: A0A803YSU9
uniprot id: G1NDC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

9103:BMT2
gene id: 9103:BMT2
uniprot id: A0A803XMQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

9103:ATF2
gene id: 9103:ATF2
uniprot id: G1NBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a dimer and can form a homodimer in the absence of DNA.
messages: Nucleus
messages: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3').

9103:PPFIA1
gene id: 9103:PPFIA1
uniprot id: A0A803Y2S4
uniprot id: A0A803Y4W1
uniprot id: A0A803Y643
uniprot id: A0A803YM86
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

9103:HSPA8
gene id: 9103:HSPA8
uniprot id: G1MSW3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9103:NINJ2
gene id: 9103:NINJ2
uniprot id: A0A803XNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

9103:KPNA3
gene id: 9103:KPNA3
uniprot id: A0A803YDA8
names: Similarity
messages: Belongs to the importin alpha family.

9103:TMEM150C
gene id: 9103:TMEM150C
uniprot id: G1N7I7
names: Subcellular Location Annotation
messages: Membrane

9103:SERPINB1
gene id: 9103:SERPINB1
uniprot id: G1MYU4
names: Similarity
messages: Belongs to the serpin family.

9103:ITPRIP
gene id: 9103:ITPRIP
uniprot id: G1NQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

9103:LOC100548533
gene id: 9103:LOC100548533
uniprot id: G1NDP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9103:LOC100546062
gene id: 9103:LOC100546062
uniprot id: G1MQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9103:SDC2
gene id: 9103:SDC2
uniprot id: Q5I5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9103:SPP1
gene id: 9103:SPP1
uniprot id: G1N6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

9103:FBXO9
gene id: 9103:FBXO9
uniprot id: G1NMD1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9).
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and acts as a regulator of mTOR signaling.

9103:ADTRP
gene id: 9103:ADTRP
uniprot id: A0A803XXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

9103:KIF26B
gene id: 9103:KIF26B
uniprot id: G1NFX3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:PARN
gene id: 9103:PARN
uniprot id: G1MQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm

9103:LOC100540306
gene id: 9103:LOC100540306
uniprot id: A0A803YR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9103:GANC
gene id: 9103:GANC
uniprot id: G1NG17
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

9103:OTC
gene id: 9103:OTC
uniprot id: G1NP50
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

9103:TBX22
gene id: 9103:TBX22
uniprot id: G1MSC0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9103:LOC100548634
gene id: 9103:LOC100548634
uniprot id: G1NPZ7
names: Similarity
messages: Belongs to the globin family.

9103:GPAM
gene id: 9103:GPAM
uniprot id: G1NEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

9103:MAP2K5
gene id: 9103:MAP2K5
uniprot id: A0A803YQP7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:LOC104909279
gene id: 9103:LOC104909279
uniprot id: G3UTY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9103:SFMBT2
gene id: 9103:SFMBT2
uniprot id: G1MYG7
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100550948
gene id: 9103:LOC100550948
uniprot id: G1N705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

9103:TRAPPC3L
gene id: 9103:TRAPPC3L
uniprot id: G1NKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9103:PDE4C
gene id: 9103:PDE4C
uniprot id: A0A803Y1T7
uniprot id: A0A803YSS2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:TOP2B
gene id: 9103:TOP2B
uniprot id: G1NF24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

9103:SEMA5A
gene id: 9103:SEMA5A
uniprot id: A0A803XW49
uniprot id: G1N3B5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:PARP11
gene id: 9103:PARP11
uniprot id: G1NMA8
uniprot id: G1NMA9
names: Similarity
messages: Belongs to the ARTD/PARP family.

9103:CD82
gene id: 9103:CD82
uniprot id: G1NDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9103:RPL31
gene id: 9103:RPL31
uniprot id: G1NPL8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

9103:MAP2K6
gene id: 9103:MAP2K6
uniprot id: G1N4E6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:ANAPC10
gene id: 9103:ANAPC10
uniprot id: G1MX14
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

9103:LOC100550170
gene id: 9103:LOC100550170
uniprot id: A0A803YBR8
uniprot id: G1NHF4
names: Similarity
messages: Belongs to the FMC1 family.
messages: Belongs to the Luc7 family.

9103:CRY2
gene id: 9103:CRY2
uniprot id: G1NF23
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

9103:ZCCHC8
gene id: 9103:ZCCHC8
uniprot id: G1MZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

9103:XKR9
gene id: 9103:XKR9
uniprot id: G1NG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9103:NFE2L1
gene id: 9103:NFE2L1
uniprot id: H9H077
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

9103:POLR1C
gene id: 9103:POLR1C
uniprot id: G1NEV0
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

9103:PRLR
gene id: 9103:PRLR
uniprot id: Q91094
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

9103:CAPN3
gene id: 9103:CAPN3
uniprot id: G1NG52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

9103:GPR65
gene id: 9103:GPR65
uniprot id: G1NR06
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:GALR1
gene id: 9103:GALR1
uniprot id: G1N7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9103:TVP23B
gene id: 9103:TVP23B
uniprot id: A0A803YKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

9103:ST8SIA5
gene id: 9103:ST8SIA5
uniprot id: G3UPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:MYO1C
gene id: 9103:MYO1C
uniprot id: G1N0G6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:LOC100550171
gene id: 9103:LOC100550171
uniprot id: G1NS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:ALOX5
gene id: 9103:ALOX5
uniprot id: G1N6U6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CSNK1E
gene id: 9103:CSNK1E
uniprot id: G1NIL4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:CHST13
gene id: 9103:CHST13
uniprot id: A0A803Y5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:VTI1B
gene id: 9103:VTI1B
uniprot id: G1NHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9103:PPA1
gene id: 9103:PPA1
uniprot id: G1N1A9
names: Similarity
messages: Belongs to the PPase family.

9103:HAAO
gene id: 9103:HAAO
uniprot id: G1NCG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

9103:LOC104914070
gene id: 9103:LOC104914070
uniprot id: G1NAB9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9103:ANXA7
gene id: 9103:ANXA7
uniprot id: G1N4G4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9103:NSG1
gene id: 9103:NSG1
uniprot id: G1NJA0
names: Similarity
messages: Belongs to the NSG family.

9103:RAD51D
gene id: 9103:RAD51D
uniprot id: G1MYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
messages: Nucleus

9103:LOC100539048
gene id: 9103:LOC100539048
uniprot id: G1N2Z8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9103:CTNND1
gene id: 9103:CTNND1
uniprot id: G1NBL8
uniprot id: G3URR3
names: Similarity
messages: Belongs to the beta-catenin family.

9103:GNPNAT1
gene id: 9103:GNPNAT1
uniprot id: G1NM07
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

9103:MAFB
gene id: 9103:MAFB
uniprot id: G1MW90
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

9103:LOC100549877
gene id: 9103:LOC100549877
uniprot id: G1MZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:ATP1B4
gene id: 9103:ATP1B4
uniprot id: G1N6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9103:RYBP
gene id: 9103:RYBP
uniprot id: G1NBE8
names: Subcellular Location Annotation
messages: Nucleus

9103:RAPGEF6
gene id: 9103:RAPGEF6
uniprot id: A0A803XWK5
uniprot id: A0A803Y9I7
uniprot id: A0A803YN52
names: Similarity
messages: Belongs to the RAPGEF2 family.

9103:RPS19BP1
gene id: 9103:RPS19BP1
uniprot id: G1NIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

9103:TSEN54
gene id: 9103:TSEN54
uniprot id: G1NB99
names: Similarity
messages: Belongs to the SEN54 family.

9103:BPNT1
gene id: 9103:BPNT1
uniprot id: G1NAF6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9103:HSP90AA1
gene id: 9103:HSP90AA1
uniprot id: G1NKX1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

9103:STN1
gene id: 9103:STN1
uniprot id: A0A803YGQ9
uniprot id: G1NDL9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

9103:GPX1
gene id: 9103:GPX1
uniprot id: D2J267
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9103:EZH2
gene id: 9103:EZH2
uniprot id: A0A803YEW3
uniprot id: G1MRP0
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC104910021
gene id: 9103:LOC104910021
uniprot id: A0A803XM39
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

9103:MAGT1
gene id: 9103:MAGT1
uniprot id: G1N353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:CCNB3
gene id: 9103:CCNB3
uniprot id: G1NBT7
names: Similarity
messages: Belongs to the cyclin family.

9103:KCNAB1
gene id: 9103:KCNAB1
uniprot id: G1NE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9103:LOC100550646
gene id: 9103:LOC100550646
uniprot id: G1MTP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9103:ARVCF
gene id: 9103:ARVCF
uniprot id: A0A803XKG3
uniprot id: G1MRS8
names: Similarity
messages: Belongs to the beta-catenin family.

9103:OCSTAMP
gene id: 9103:OCSTAMP
uniprot id: A0A803YEQ0
names: Subcellular Location Annotation
messages: Membrane

9103:PPARGC1A
gene id: 9103:PPARGC1A
uniprot id: G3X8N5
names: Subcellular Location Annotation
messages: PML body

9103:CAPN8
gene id: 9103:CAPN8
uniprot id: G1N8W2
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:PELO
gene id: 9103:PELO
uniprot id: H9H248
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

9103:OTOP1
gene id: 9103:OTOP1
uniprot id: G1NJ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9103:GSTA1.1
gene id: 9103:GSTA1.1
uniprot id: C8BLR1
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9103:IAPP
gene id: 9103:IAPP
uniprot id: G1NLJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

9103:ADRB1
gene id: 9103:ADRB1
uniprot id: P07700
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (PubMed:18594507). In dorsal pons neurons, involved in the regulation of sleep/wake behaviors (By similarity).
messages: Cell membrane
messages: Early endosome
messages: Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.

9103:LOC100539172
gene id: 9103:LOC100539172
uniprot id: G1MQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9103:PRPF3
gene id: 9103:PRPF3
uniprot id: G1MPX0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

9103:FGF12
gene id: 9103:FGF12
uniprot id: G1N612
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9103:PTPN14
gene id: 9103:PTPN14
uniprot id: G1NBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9103:STC2
gene id: 9103:STC2
uniprot id: A0A803XRK5
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9103:NUP107
gene id: 9103:NUP107
uniprot id: G1NDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

9103:PDCD5
gene id: 9103:PDCD5
uniprot id: G1N1P5
names: Similarity
messages: Belongs to the PDCD5 family.

9103:VGLL1
gene id: 9103:VGLL1
uniprot id: G1MWZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

9103:SP4
gene id: 9103:SP4
uniprot id: A0A803XKL6
names: Subcellular Location Annotation
messages: Nucleus

9103:PABPC1L
gene id: 9103:PABPC1L
uniprot id: G1MXJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9103:PHF19
gene id: 9103:PHF19
uniprot id: G1MWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9103:LOC104911466
gene id: 9103:LOC104911466
uniprot id: A0A803XPT8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

9103:ADGRL4
gene id: 9103:ADGRL4
uniprot id: G1NAS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:LOC723978
gene id: 9103:LOC723978
uniprot id: Q71SZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9103:TAGLN
gene id: 9103:TAGLN
uniprot id: G1MWA7
names: Similarity
messages: Belongs to the calponin family.

9103:MYMK
gene id: 9103:MYMK
uniprot id: G1N4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

9103:ICOS
gene id: 9103:ICOS
uniprot id: G1N9B1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

9103:LOC100540365
gene id: 9103:LOC100540365
uniprot id: G1NP40
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

9103:LOC100546642
gene id: 9103:LOC100546642
uniprot id: G1N5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9103:FAM171A1
gene id: 9103:FAM171A1
uniprot id: G1N7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9103:BZW1
gene id: 9103:BZW1
uniprot id: G1N6K0
names: Similarity
messages: Belongs to the BZW family.

9103:STOML1
gene id: 9103:STOML1
uniprot id: G1MVN0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9103:RGS5
gene id: 9103:RGS5
uniprot id: G5E7W9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

9103:LOC100542338
gene id: 9103:LOC100542338
uniprot id: G1MQ72
uniprot id: G3UV43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

9103:MASTL
gene id: 9103:MASTL
uniprot id: G1N4L2
names: Subcellular Location Annotation
messages: Nucleus
messages: centrosome

9103:HLCS
gene id: 9103:HLCS
uniprot id: G1NNY4
names: Similarity
messages: Belongs to the biotin--protein ligase family.

9103:JPT1
gene id: 9103:JPT1
uniprot id: G1NAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

9103:SIDT2
gene id: 9103:SIDT2
uniprot id: G1MW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

9103:ACTB
gene id: 9103:ACTB
uniprot id: Q58J72
names: Similarity
messages: Belongs to the actin family.

9103:CASK
gene id: 9103:CASK
uniprot id: A0A803XUJ1
uniprot id: A0A803YEH6
uniprot id: A0A803YJ82
uniprot id: G1NP41
names: Similarity
messages: Belongs to the MAGUK family.

9103:FAM168A
gene id: 9103:FAM168A
uniprot id: A0A803YEC9
names: Similarity
messages: Belongs to the FAM168 family.

9103:TCTN1
gene id: 9103:TCTN1
uniprot id: G1N0H8
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

9103:LIN54
gene id: 9103:LIN54
uniprot id: G1N7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

9103:TMCO3
gene id: 9103:TMCO3
uniprot id: G1NPR3
names: Subcellular Location Annotation
messages: Membrane

9103:SEMA3F
gene id: 9103:SEMA3F
uniprot id: A0A803XWA9
uniprot id: G1MYJ4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:N4BP3
gene id: 9103:N4BP3
uniprot id: G1MY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

9103:KIFC3
gene id: 9103:KIFC3
uniprot id: G1MW95
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:TYRO3
gene id: 9103:TYRO3
uniprot id: G1NFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

9103:NDUFA2
gene id: 9103:NDUFA2
uniprot id: A0A803YBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9103:SLC41A3
gene id: 9103:SLC41A3
uniprot id: A0A803Y7U5
uniprot id: G1N6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9103:TMPRSS13
gene id: 9103:TMPRSS13
uniprot id: G1MXD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:HMX2
gene id: 9103:HMX2
uniprot id: G1NGF2
names: Subcellular Location Annotation
messages: Nucleus

9103:CER1
gene id: 9103:CER1
uniprot id: G1N1X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:CWC25
gene id: 9103:CWC25
uniprot id: G1N0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

9103:TRNAU1AP
gene id: 9103:TRNAU1AP
uniprot id: G1MTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

9103:STRADB
gene id: 9103:STRADB
uniprot id: G1N7E1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

9103:IP6K1
gene id: 9103:IP6K1
uniprot id: G1MVY4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9103:THEMIS
gene id: 9103:THEMIS
uniprot id: G1NKM7
names: Similarity
messages: Belongs to the themis family.

9103:SLC5A11
gene id: 9103:SLC5A11
uniprot id: A0A803YBP2
uniprot id: G1N3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9103:RAD50
gene id: 9103:RAD50
uniprot id: G1N9X5
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

9103:SLC39A3
gene id: 9103:SLC39A3
uniprot id: G1MYS2
names: Subcellular Location Annotation
messages: Membrane

9103:NUP35
gene id: 9103:NUP35
uniprot id: G1MYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

9103:PICK1
gene id: 9103:PICK1
uniprot id: G1NIS1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

9103:IRF1
gene id: 9103:IRF1
uniprot id: G1N9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

9103:OPTN
gene id: 9103:OPTN
uniprot id: G1MZZ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

9103:SRMS
gene id: 9103:SRMS
uniprot id: G1N3Z8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9103:OTUD7A
gene id: 9103:OTUD7A
uniprot id: G1MZM7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:TCEANC
gene id: 9103:TCEANC
uniprot id: G1NPD1
names: Subcellular Location Annotation
messages: Nucleus

9103:LANCL1
gene id: 9103:LANCL1
uniprot id: A0A803Y7M2
names: Similarity
messages: Belongs to the LanC-like protein family.

9103:DPYS
gene id: 9103:DPYS
uniprot id: G1NID7
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

9103:LEO1
gene id: 9103:LEO1
uniprot id: G1N3S2
names: Similarity
messages: Belongs to the LEO1 family.

9103:FAM126A
gene id: 9103:FAM126A
uniprot id: A0A803Y8S2
uniprot id: G1NDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9103:DLGAP5
gene id: 9103:DLGAP5
uniprot id: A0A803XRM9
uniprot id: A0A803XU49
names: Similarity
messages: Belongs to the SAPAP family.

9103:SLC7A9
gene id: 9103:SLC7A9
uniprot id: G1N206
names: Subcellular Location Annotation
messages: Membrane

9103:CHRNA1
gene id: 9103:CHRNA1
uniprot id: G1NBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:SUGP1
gene id: 9103:SUGP1
uniprot id: A0A803Y043
names: Subcellular Location Annotation
messages: Nucleus

9103:ALX1
gene id: 9103:ALX1
uniprot id: G1NF54
names: Subcellular Location Annotation
messages: Nucleus

9103:GTF2E2
gene id: 9103:GTF2E2
uniprot id: G1N0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

9103:LOC104914091
gene id: 9103:LOC104914091
uniprot id: A0A803YL81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

9103:NSF
gene id: 9103:NSF
uniprot id: A0A803YM82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

9103:SH3BGRL3
gene id: 9103:SH3BGRL3
uniprot id: A0A803YAI4
names: Similarity
messages: Belongs to the SH3BGR family.

9103:VPS72
gene id: 9103:VPS72
uniprot id: G1MQY4
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

9103:LOC100546335
gene id: 9103:LOC100546335
uniprot id: G1NE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:P2RY1
gene id: 9103:P2RY1
uniprot id: P49652
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Mainly found in blood, brain, and lung. To a lesser extent in stomach, gut and skeletal muscle.
messages: Receptor for extracellular adenine nucleotides such as ADP (PubMed:8058061). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (By similarity).

9103:CHMP1A
gene id: 9103:CHMP1A
uniprot id: G1N7T3
names: Similarity
messages: Belongs to the SNF7 family.

9103:MED21
gene id: 9103:MED21
uniprot id: G1NLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9103:ADORA2B
gene id: 9103:ADORA2B
uniprot id: G1N3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9103:ND4L
gene id: 9103:ND4L
uniprot id: A9XBE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

9103:LOC100541720
gene id: 9103:LOC100541720
uniprot id: G1MZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

9103:GSTA2
gene id: 9103:GSTA2
uniprot id: C8BLR4
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9103:TPRA1
gene id: 9103:TPRA1
uniprot id: G1N6A4
uniprot id: G3US44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

9103:SLC26A2
gene id: 9103:SLC26A2
uniprot id: G1MVS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

9103:SLC30A10
gene id: 9103:SLC30A10
uniprot id: A0A803YJE7
uniprot id: G1NAK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9103:LOC100540676
gene id: 9103:LOC100540676
uniprot id: A0A803YR76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

9103:TBC1D24
gene id: 9103:TBC1D24
uniprot id: A0A803Y2N0
uniprot id: A0A803Y823
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

9103:LOC100544587
gene id: 9103:LOC100544587
uniprot id: G1NK74
names: Similarity
messages: Belongs to the CCDC53 family.

9103:POLR1E
gene id: 9103:POLR1E
uniprot id: G1NA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

9103:SFR1
gene id: 9103:SFR1
uniprot id: G1NDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

9103:STT3A
gene id: 9103:STT3A
uniprot id: G1MPX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

9103:SMAD2
gene id: 9103:SMAD2
uniprot id: G1MRI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9103:LOC100539658
gene id: 9103:LOC100539658
uniprot id: G1MW70
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9103:RDH10
gene id: 9103:RDH10
uniprot id: G1NG63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:AMOT
gene id: 9103:AMOT
uniprot id: G1N3G8
names: Similarity
messages: Belongs to the angiomotin family.

9103:BCO2
gene id: 9103:BCO2
uniprot id: G1MZC3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

9103:PATL2
gene id: 9103:PATL2
uniprot id: G1MRG0
names: Similarity
messages: Belongs to the PAT1 family.

9103:KRR1
gene id: 9103:KRR1
uniprot id: G1NEE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

9103:LOC100539205
gene id: 9103:LOC100539205
uniprot id: G1N309
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9103:LOC100541214
gene id: 9103:LOC100541214
uniprot id: G1N6T5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ALDH18A1
gene id: 9103:ALDH18A1
uniprot id: G1NH79
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

9103:TCP10L2
gene id: 9103:TCP10L2
uniprot id: A0A803YSD4
names: Similarity
messages: Belongs to the TCP10 family.

9103:LOC100549107
gene id: 9103:LOC100549107
uniprot id: G1NHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

9103:HOXD12
gene id: 9103:HOXD12
uniprot id: G1NBH7
names: Subcellular Location Annotation
messages: Nucleus

9103:SSTR3
gene id: 9103:SSTR3
uniprot id: G1NIZ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:LOC100550516
gene id: 9103:LOC100550516
uniprot id: G1N0P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

9103:MARK1
gene id: 9103:MARK1
uniprot id: A0A803XPM4
uniprot id: G1NA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9103:HASPIN
gene id: 9103:HASPIN
uniprot id: A0A803Y4U1
names: Subcellular Location Annotation
messages: Chromosome

9103:LOC100541961
gene id: 9103:LOC100541961
uniprot id: A0A803XZR2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9103:SPDEF
gene id: 9103:SPDEF
uniprot id: H9H0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:LOC104909308
gene id: 9103:LOC104909308
uniprot id: A0A803YPF0
names: Similarity
messages: Belongs to the SCM family.

9103:ZDHHC6
gene id: 9103:ZDHHC6
uniprot id: G1NEM3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9103:WASF3
gene id: 9103:WASF3
uniprot id: A0A803XRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9103:LAMC2
gene id: 9103:LAMC2
uniprot id: G1MSC8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9103:NPB
gene id: 9103:NPB
uniprot id: A0A803XT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

9103:LOC100548327
gene id: 9103:LOC100548327
uniprot id: G1NQU6
names: Similarity
messages: Belongs to the folate receptor family.

9103:RAMP2
gene id: 9103:RAMP2
uniprot id: A0A803YN35
names: Similarity
messages: Belongs to the RAMP family.

9103:NDUFS7
gene id: 9103:NDUFS7
uniprot id: G1MY84
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

9103:MPC2
gene id: 9103:MPC2
uniprot id: G1NNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

9103:DRAXIN
gene id: 9103:DRAXIN
uniprot id: G1N3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

9103:LOC100543750
gene id: 9103:LOC100543750
uniprot id: G1NM58
names: Similarity
messages: Belongs to the ARTD/PARP family.

9103:CA12
gene id: 9103:CA12
uniprot id: G1MY57
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9103:SMG1
gene id: 9103:SMG1
uniprot id: G1N769
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

9103:EPYC
gene id: 9103:EPYC
uniprot id: G1NFI9
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9103:SAR1B
gene id: 9103:SAR1B
uniprot id: G1N8D5
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

9103:PCMTD2
gene id: 9103:PCMTD2
uniprot id: A0A803YGH2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9103:MFAP1
gene id: 9103:MFAP1
uniprot id: A0A803XSF8
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

9103:RPS24
gene id: 9103:RPS24
uniprot id: G1N224
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

9103:CEP57
gene id: 9103:CEP57
uniprot id: A0A803Y2W7
uniprot id: G1NQL4
names: Similarity
messages: Belongs to the translokin family.

9103:SLC1A7
gene id: 9103:SLC1A7
uniprot id: G1NFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9103:SELENOF
gene id: 9103:SELENOF
uniprot id: M9P293
names: Similarity
messages: Belongs to the selenoprotein M/F family.

9103:UBE2R2
gene id: 9103:UBE2R2
uniprot id: G1MSS2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:LOC100546469
gene id: 9103:LOC100546469
uniprot id: G1MRQ1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9103:TMEM170B
gene id: 9103:TMEM170B
uniprot id: A0A803Y2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

9103:RGN
gene id: 9103:RGN
uniprot id: G1NPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9103:STING1
gene id: 9103:STING1
uniprot id: A0A803YGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: autophagosome membrane
messages: perinuclear region

9103:TAF1D
gene id: 9103:TAF1D
uniprot id: G1NQN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

9103:LOC104909720
gene id: 9103:LOC104909720
uniprot id: G1NEN7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:DMRT2
gene id: 9103:DMRT2
uniprot id: G1NS45
names: Similarity
messages: Belongs to the DMRT family.

9103:FGF8
gene id: 9103:FGF8
uniprot id: G1NQY5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9103:SF3A2
gene id: 9103:SF3A2
uniprot id: G1MSY8
names: Similarity
messages: Belongs to the SF3A2 family.

9103:ATP6V1G3
gene id: 9103:ATP6V1G3
uniprot id: G1N2D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9103:GJC1
gene id: 9103:GJC1
uniprot id: G1NDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9103:GLI3
gene id: 9103:GLI3
uniprot id: A0A803YD02
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

9103:TMSB15B
gene id: 9103:TMSB15B
uniprot id: A0A803XNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9103:ODC1
gene id: 9103:ODC1
uniprot id: G1NMK7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9103:LOC100540835
gene id: 9103:LOC100540835
uniprot id: G1NLM4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:DDB2
gene id: 9103:DDB2
uniprot id: A0A803XV87
uniprot id: G1NE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

9103:VSIG1
gene id: 9103:VSIG1
uniprot id: A0A803YLE5
uniprot id: G1N4X1
names: Subcellular Location Annotation
messages: Membrane

9103:CPSF2
gene id: 9103:CPSF2
uniprot id: G1NKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

9103:LOC100545337
gene id: 9103:LOC100545337
uniprot id: G1N7P3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:IGF2BP1
gene id: 9103:IGF2BP1
uniprot id: G1MUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm

9103:LOC100546153
gene id: 9103:LOC100546153
uniprot id: A0A803XZ67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

9103:LOC100542776
gene id: 9103:LOC100542776
uniprot id: G1NNG8
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9103:LOC100544088
gene id: 9103:LOC100544088
uniprot id: A0A803XPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9103:LOC100542342
gene id: 9103:LOC100542342
uniprot id: G1MUV8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:PAFAH1B1
gene id: 9103:PAFAH1B1
uniprot id: G1N8Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

9103:RPLP2
gene id: 9103:RPLP2
uniprot id: G1NA41
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9103:AP1S2
gene id: 9103:AP1S2
uniprot id: G1NPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

9103:TES
gene id: 9103:TES
uniprot id: G1N9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

9103:SHROOM1
gene id: 9103:SHROOM1
uniprot id: A0A803Y281
uniprot id: A0A803Y7U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9103:PDP1
gene id: 9103:PDP1
uniprot id: A0A803XLU7
names: Similarity
messages: Belongs to the PP2C family.

9103:PTP4A1
gene id: 9103:PTP4A1
uniprot id: G1NM78
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9103:HEXA
gene id: 9103:HEXA
uniprot id: G1MRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9103:LOC100550886
gene id: 9103:LOC100550886
uniprot id: A0A803Y5I3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

9103:LOC100542048
gene id: 9103:LOC100542048
uniprot id: A0A803XME0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:LOC100303683
gene id: 9103:LOC100303683
uniprot id: Q91085
names: Developmental Stage
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Expressed in pituitary, hypothalamus, small intestine and ovarian follicles.
messages: Pituitary levels are highest in non-photostimulated and incubating birds and lower in photostimulated, laying and photorefractory birds.
messages: Pituitary levels decrease on VIP immunization.
messages: This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9103:FNIP1
gene id: 9103:FNIP1
uniprot id: G1N948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

9103:CLDN3
gene id: 9103:CLDN3
uniprot id: G1N4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9103:PSMF1
gene id: 9103:PSMF1
uniprot id: G1N7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

9103:ORC2
gene id: 9103:ORC2
uniprot id: G1N6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

9103:KIF20A
gene id: 9103:KIF20A
uniprot id: G1MXT8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:PARP14
gene id: 9103:PARP14
uniprot id: G1NI25
names: Similarity
messages: Belongs to the ARTD/PARP family.

9103:SQLE
gene id: 9103:SQLE
uniprot id: G1NJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

9103:ETF1
gene id: 9103:ETF1
uniprot id: G1MRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

9103:GDI2
gene id: 9103:GDI2
uniprot id: G1MWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

9103:DGAT2
gene id: 9103:DGAT2
uniprot id: A0A803YCE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TMEM231
gene id: 9103:TMEM231
uniprot id: G1NA37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

9103:SLC29A1
gene id: 9103:SLC29A1
uniprot id: G1NEB4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

9103:PLCB2
gene id: 9103:PLCB2
uniprot id: Q91086
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9103:NR4A3
gene id: 9103:NR4A3
uniprot id: G1N700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9103:LMOD2
gene id: 9103:LMOD2
uniprot id: G1N8E8
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9103:ARRDC2
gene id: 9103:ARRDC2
uniprot id: H9H0N6
names: Similarity
messages: Belongs to the arrestin family.

9103:TRAF4
gene id: 9103:TRAF4
uniprot id: G1NJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9103:PPP2R5C
gene id: 9103:PPP2R5C
uniprot id: G1NKU8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

9103:GRIA3
gene id: 9103:GRIA3
uniprot id: G3UQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9103:SLC4A7
gene id: 9103:SLC4A7
uniprot id: A0A803YEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

9103:GLB1
gene id: 9103:GLB1
uniprot id: G1NGW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9103:SDC3
gene id: 9103:SDC3
uniprot id: Q5I5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9103:TCEA3
gene id: 9103:TCEA3
uniprot id: G1MS07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

9103:LOC100543241
gene id: 9103:LOC100543241
uniprot id: G1NQJ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9103:UNC5D
gene id: 9103:UNC5D
uniprot id: G1MSM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9103:GATAD2A
gene id: 9103:GATAD2A
uniprot id: A0A803YSV8
uniprot id: G1MY40
uniprot id: G3UTW4
names: Subcellular Location Annotation
messages: Nucleus

9103:LIG4
gene id: 9103:LIG4
uniprot id: G1NR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9103:C2H6orf120
gene id: 9103:C2H6orf120
uniprot id: G1NRR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

9103:HNF4G
gene id: 9103:HNF4G
uniprot id: G1NGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9103:TET2
gene id: 9103:TET2
uniprot id: G1N320
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9103:WNT5A
gene id: 9103:WNT5A
uniprot id: A0A803YDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9103:ATP5F1B
gene id: 9103:ATP5F1B
uniprot id: H9H062
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9103:GPN2
gene id: 9103:GPN2
uniprot id: G1MQA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

9103:PTGS2
gene id: 9103:PTGS2
uniprot id: G1MRC2
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GRM3
gene id: 9103:GRM3
uniprot id: G1N0U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

9103:B4GALT4
gene id: 9103:B4GALT4
uniprot id: A0A803Y346
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9103:RETREG1
gene id: 9103:RETREG1
uniprot id: G1N229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:TM7SF3
gene id: 9103:TM7SF3
uniprot id: G1NLS5
names: Subcellular Location Annotation
messages: Membrane

9103:SUPT6H
gene id: 9103:SUPT6H
uniprot id: G1N2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

9103:GPATCH11
gene id: 9103:GPATCH11
uniprot id: G1NFA3
names: Similarity
messages: Belongs to the GPATCH11 family.

9103:NSDHL
gene id: 9103:NSDHL
uniprot id: G1N1E3
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9103:LOC100540961
gene id: 9103:LOC100540961
uniprot id: G1N4P9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:ETV1
gene id: 9103:ETV1
uniprot id: A0A803Y169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:ACAN
gene id: 9103:ACAN
uniprot id: A0A803XTU4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9103:TBP
gene id: 9103:TBP
uniprot id: G1NHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

9103:DAZL
gene id: 9103:DAZL
uniprot id: A0A803YCJ1
uniprot id: G1NEH8
names: Subcellular Location Annotation
messages: Cytoplasm

9103:SKAP1
gene id: 9103:SKAP1
uniprot id: A0A803Y384
uniprot id: A0A803YC35
names: Similarity
messages: Belongs to the SKAP family.

9103:STON1
gene id: 9103:STON1
uniprot id: G1N1Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

9103:CHST4
gene id: 9103:CHST4
uniprot id: G1NRE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9103:TIPIN
gene id: 9103:TIPIN
uniprot id: G1NBZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

9103:ANTXRL
gene id: 9103:ANTXRL
uniprot id: G1N7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9103:CHST9
gene id: 9103:CHST9
uniprot id: G1ND74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:LOC109367730
gene id: 9103:LOC109367730
uniprot id: A0A803YF62
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9103:TMTC3
gene id: 9103:TMTC3
uniprot id: A0A803XYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9103:ST6GAL1
gene id: 9103:ST6GAL1
uniprot id: A0A803Y956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:AFF1
gene id: 9103:AFF1
uniprot id: G1N6P9
names: Similarity
messages: Belongs to the AF4 family.

9103:MMP2
gene id: 9103:MMP2
uniprot id: Q6U7G9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

9103:MTTP
gene id: 9103:MTTP
uniprot id: A0A803Y1Y8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CUL1
gene id: 9103:CUL1
uniprot id: G1MRX7
names: Similarity
messages: Belongs to the cullin family.

9103:MTMR3
gene id: 9103:MTMR3
uniprot id: A0A803XYW5
uniprot id: A0A803YEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

9103:LOC100544938
gene id: 9103:LOC100544938
uniprot id: H9H1X1
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:IRF4
gene id: 9103:IRF4
uniprot id: G1MYY4
uniprot id: G3URE6
names: Subcellular Location Annotation
messages: Nucleus

9103:PRKAB1
gene id: 9103:PRKAB1
uniprot id: G1NA04
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9103:CHST1
gene id: 9103:CHST1
uniprot id: G1NRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9103:LRRC9
gene id: 9103:LRRC9
uniprot id: G1NLG7
names: Similarity
messages: Belongs to the SDS22 family.

9103:DNAJA4
gene id: 9103:DNAJA4
uniprot id: G1MXG7
names: Subcellular Location Annotation
messages: Membrane

9103:CNTF
gene id: 9103:CNTF
uniprot id: G1NBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

9103:LOC100546242
gene id: 9103:LOC100546242
uniprot id: G1MYV1
names: Similarity
messages: Belongs to the serpin family.

9103:SKP1
gene id: 9103:SKP1
uniprot id: G1N8G6
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

9103:CHD1L
gene id: 9103:CHD1L
uniprot id: A0A803XPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9103:NHSL2
gene id: 9103:NHSL2
uniprot id: A0A803XYI1
uniprot id: G1MTA4
names: Similarity
messages: Belongs to the NHS family.

9103:LOC100544064
gene id: 9103:LOC100544064
uniprot id: G3UR26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:RAD17
gene id: 9103:RAD17
uniprot id: G1MTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

9103:EIF5
gene id: 9103:EIF5
uniprot id: G1NL07
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

9103:OTOP3
gene id: 9103:OTOP3
uniprot id: G1NAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9103:TMEM45A
gene id: 9103:TMEM45A
uniprot id: G1NNH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9103:DAP3
gene id: 9103:DAP3
uniprot id: G1MQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

9103:LOC723983
gene id: 9103:LOC723983
uniprot id: Q9IAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

9103:DUOX2
gene id: 9103:DUOX2
uniprot id: G1MQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

9103:NONO
gene id: 9103:NONO
uniprot id: G1MYJ8
names: Subcellular Location Annotation
messages: Nucleus speckle

9103:IL15
gene id: 9103:IL15
uniprot id: G1MW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

9103:LOC100546123
gene id: 9103:LOC100546123
uniprot id: G1MTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

9103:SDR42E1
gene id: 9103:SDR42E1
uniprot id: G1N520
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9103:TCP1
gene id: 9103:TCP1
uniprot id: G1NIP3
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

9103:IL26
gene id: 9103:IL26
uniprot id: G1NDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9103:C3H8orf37
gene id: 9103:C3H8orf37
uniprot id: G1NHP4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

9103:LOC100544929
gene id: 9103:LOC100544929
uniprot id: G1MQ16
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9103:OLFM3
gene id: 9103:OLFM3
uniprot id: G1N4M6
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9103:PAX7
gene id: 9103:PAX7
uniprot id: D2KKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9103:TEKT2
gene id: 9103:TEKT2
uniprot id: G1MXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

9103:SLC1A6
gene id: 9103:SLC1A6
uniprot id: A0A803XUX7
uniprot id: G1MQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9103:BIRC2
gene id: 9103:BIRC2
uniprot id: G1NQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

9103:MRPS21
gene id: 9103:MRPS21
uniprot id: G1MPV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

9103:ND3
gene id: 9103:ND3
uniprot id: A9XBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

9103:LOC100551323
gene id: 9103:LOC100551323
uniprot id: G1MXR8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:LOC100546708
gene id: 9103:LOC100546708
uniprot id: G1NKP8
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:MOSPD1
gene id: 9103:MOSPD1
uniprot id: G1MWD2
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100542219
gene id: 9103:LOC100542219
uniprot id: G1N6L0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:MET
gene id: 9103:MET
uniprot id: G1N9U2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NR1H4
gene id: 9103:NR1H4
uniprot id: G3UT50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

9103:EYA3
gene id: 9103:EYA3
uniprot id: A0A803XXB0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9103:LOC100545239
gene id: 9103:LOC100545239
uniprot id: G1N291
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9103:LOC104912428
gene id: 9103:LOC104912428
uniprot id: G1NGG6
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:CBFB
gene id: 9103:CBFB
uniprot id: A0A803YQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

9103:LOC100551262
gene id: 9103:LOC100551262
uniprot id: A0A803Y725
uniprot id: G1NC34
names: Subcellular Location Annotation
messages: cytoskeleton

9103:PPP2R5E
gene id: 9103:PPP2R5E
uniprot id: G1NLC0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

9103:PODXL
gene id: 9103:PODXL
uniprot id: A0A803XTN2
uniprot id: G1MXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

9103:LOC100551074
gene id: 9103:LOC100551074
uniprot id: G1MTI3
uniprot id: G3UQT8
names: Subcellular Location Annotation
messages: Membrane

9103:CSRNP1
gene id: 9103:CSRNP1
uniprot id: A0A803YL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9103:LOC100541482
gene id: 9103:LOC100541482
uniprot id: G1MQ38
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:RHBDF1
gene id: 9103:RHBDF1
uniprot id: A0A803XKG9
uniprot id: G1N9A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

9103:TBPL2
gene id: 9103:TBPL2
uniprot id: G1NLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

9103:UBR2
gene id: 9103:UBR2
uniprot id: A0A803Y547
uniprot id: G1NC88
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9103:TAC1
gene id: 9103:TAC1
uniprot id: A0A803Y4K1
uniprot id: G1NBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

9103:LOC100550599
gene id: 9103:LOC100550599
uniprot id: G3UUX2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:MCM5
gene id: 9103:MCM5
uniprot id: G1NJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

9103:BTF3L4
gene id: 9103:BTF3L4
uniprot id: G1NF34
names: Similarity
messages: Belongs to the NAC-beta family.

9103:LOC100543904
gene id: 9103:LOC100543904
uniprot id: G1MVL9
names: Subcellular Location Annotation
messages: Membrane

9103:GRAMD1B
gene id: 9103:GRAMD1B
uniprot id: A0A803YNK6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:PLXNB2
gene id: 9103:PLXNB2
uniprot id: G3US56
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:BRINP3
gene id: 9103:BRINP3
uniprot id: G1MRI8
names: Similarity
messages: Belongs to the BRINP family.

9103:TF
gene id: 9103:TF
uniprot id: Q53HY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

9103:STC1
gene id: 9103:STC1
uniprot id: A0A803XW77
uniprot id: G1MR66
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9103:PRL
gene id: 9103:PRL
uniprot id: E5RWR3
uniprot id: P17572
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted
messages: Three forms are found, non-glycosylated, glycosylated and one form seems to be only O-glycosylated.

9103:POPDC2
gene id: 9103:POPDC2
uniprot id: G1NNA5
names: Similarity
messages: Belongs to the popeye family.

9103:MEF2B
gene id: 9103:MEF2B
uniprot id: G1MYT4
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100543126
gene id: 9103:LOC100543126
uniprot id: H9H1T2
names: Similarity
messages: Belongs to the SMARCD family.

9103:PIAS4
gene id: 9103:PIAS4
uniprot id: G1NF86
names: Similarity
messages: Belongs to the PIAS family.

9103:ALDOC
gene id: 9103:ALDOC
uniprot id: G1N2A4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9103:NIT2
gene id: 9103:NIT2
uniprot id: G1NNH2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

9103:AQP5
gene id: 9103:AQP5
uniprot id: G1NDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9103:WDYHV1
gene id: 9103:WDYHV1
uniprot id: G1NJ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

9103:NCOR2
gene id: 9103:NCOR2
uniprot id: G3US98
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

9103:RPL15
gene id: 9103:RPL15
uniprot id: G1NEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

9103:HSBP1
gene id: 9103:HSBP1
uniprot id: A0A803XTU6
names: Similarity
messages: Belongs to the HSBP1 family.

9103:INTS2
gene id: 9103:INTS2
uniprot id: G3UPW3
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

9103:KCNE4
gene id: 9103:KCNE4
uniprot id: G1N023
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9103:ARF1
gene id: 9103:ARF1
uniprot id: A0A803XSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9103:MDM4
gene id: 9103:MDM4
uniprot id: A0A803XR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

9103:CRYGN
gene id: 9103:CRYGN
uniprot id: G1MZB4
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9103:MAK16
gene id: 9103:MAK16
uniprot id: A0A803XN38
names: Similarity
messages: Belongs to the MAK16 family.

9103:CDK18
gene id: 9103:CDK18
uniprot id: A0A803YPT8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:LOC100550389
gene id: 9103:LOC100550389
uniprot id: G1NG37
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

9103:AZIN2
gene id: 9103:AZIN2
uniprot id: G1N0D8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9103:INHBB
gene id: 9103:INHBB
uniprot id: G1MX92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9103:RNF8
gene id: 9103:RNF8
uniprot id: G1NE57
names: Similarity
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.

9103:LOC100549606
gene id: 9103:LOC100549606
uniprot id: G3USA9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:SULT1C4
gene id: 9103:SULT1C4
uniprot id: G1NPP7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:LOC100542589
gene id: 9103:LOC100542589
uniprot id: G1N762
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9103:SLC7A11
gene id: 9103:SLC7A11
uniprot id: G1MUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

9103:CEP170
gene id: 9103:CEP170
uniprot id: A0A803XLY8
uniprot id: A0A803YRK7
names: Similarity
messages: Belongs to the CEP170 family.

9103:CYFIP2
gene id: 9103:CYFIP2
uniprot id: G1N0V7
names: Similarity
messages: Belongs to the CYFIP family.

9103:TRIM32
gene id: 9103:TRIM32
uniprot id: G1MW22
names: Similarity
messages: Belongs to the TRIM/RBCC family.

9103:ALOX5AP
gene id: 9103:ALOX5AP
uniprot id: G1NQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC100303693
gene id: 9103:LOC100303693
uniprot id: G1NIB8
names: Similarity
messages: Belongs to the actin family.

9103:ALG6
gene id: 9103:ALG6
uniprot id: G1NGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:DIMT1
gene id: 9103:DIMT1
uniprot id: G1MYT1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

9103:LOC100547828
gene id: 9103:LOC100547828
uniprot id: A0A803XMA3
names: Similarity
messages: Belongs to the MT-A70-like family.

9103:MYOZ1
gene id: 9103:MYOZ1
uniprot id: G1N478
names: Similarity
messages: Belongs to the myozenin family.

9103:YTHDF3
gene id: 9103:YTHDF3
uniprot id: G1NF89
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9103:NDUFA7
gene id: 9103:NDUFA7
uniprot id: A0A803Y5M6
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

9103:SLC6A11
gene id: 9103:SLC6A11
uniprot id: G1MZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9103:FAM8A1
gene id: 9103:FAM8A1
uniprot id: G1MVT7
names: Subcellular Location Annotation
messages: Membrane

9103:CENPU
gene id: 9103:CENPU
uniprot id: G1N3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

9103:TBL3
gene id: 9103:TBL3
uniprot id: G5E7H5
names: Subcellular Location Annotation
messages: nucleolus

9103:SUSD6
gene id: 9103:SUSD6
uniprot id: G1NH04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:PPEF1
gene id: 9103:PPEF1
uniprot id: G1NPA0
names: Similarity
messages: Belongs to the PPP phosphatase family.

9103:CHMP5
gene id: 9103:CHMP5
uniprot id: G1N500
names: Similarity
messages: Belongs to the SNF7 family.

9103:LIPC
gene id: 9103:LIPC
uniprot id: G1N1J3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:GPD1L
gene id: 9103:GPD1L
uniprot id: G1NFB1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

9103:AFF4
gene id: 9103:AFF4
uniprot id: G1NAC6
names: Similarity
messages: Belongs to the AF4 family.

9103:VPS51
gene id: 9103:VPS51
uniprot id: G1MUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

9103:SGPL1
gene id: 9103:SGPL1
uniprot id: G1N0U2
names: Similarity
messages: Belongs to the group II decarboxylase family.

9103:MAP2K4
gene id: 9103:MAP2K4
uniprot id: A0A803XT39
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:MAP2
gene id: 9103:MAP2
uniprot id: A0A803Y389
uniprot id: G1MYM9
names: Subcellular Location Annotation
messages: cytoskeleton

9103:CDH5
gene id: 9103:CDH5
uniprot id: G1N415
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

9103:TAF9B
gene id: 9103:TAF9B
uniprot id: G1MS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

9103:KCNJ6
gene id: 9103:KCNJ6
uniprot id: G1NNY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

9103:RFX2
gene id: 9103:RFX2
uniprot id: G1MS51
names: Subcellular Location Annotation
messages: Nucleus

9103:PEX2
gene id: 9103:PEX2
uniprot id: G1NRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

9103:DLGAP3
gene id: 9103:DLGAP3
uniprot id: G1MYN7
names: Similarity
messages: Belongs to the SAPAP family.

9103:TM4SF4
gene id: 9103:TM4SF4
uniprot id: G1NES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9103:GSK3B
gene id: 9103:GSK3B
uniprot id: A0A803YS83
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

9103:HOXD4
gene id: 9103:HOXD4
uniprot id: G1NRU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9103:CHST3
gene id: 9103:CHST3
uniprot id: G3URX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9103:DGKK
gene id: 9103:DGKK
uniprot id: A0A803YB58
uniprot id: G1NBS3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9103:MLH1
gene id: 9103:MLH1
uniprot id: G1NH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

9103:ELOVL7
gene id: 9103:ELOVL7
uniprot id: A0A803YKX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:LOC100541451
gene id: 9103:LOC100541451
uniprot id: G1MV25
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

9103:LOC104913831
gene id: 9103:LOC104913831
uniprot id: G1NAP7
names: Subcellular Location Annotation
messages: Membrane

9103:SPARC
gene id: 9103:SPARC
uniprot id: G3UNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

9103:MPEG1
gene id: 9103:MPEG1
uniprot id: G1NRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9103:LOC100550820
gene id: 9103:LOC100550820
uniprot id: A0A803XK90
names: Similarity
messages: Belongs to the actin family.

9103:RSBN1
gene id: 9103:RSBN1
uniprot id: G1N0P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

9103:NCAPD3
gene id: 9103:NCAPD3
uniprot id: G1MS44
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

9103:ABCA5
gene id: 9103:ABCA5
uniprot id: G1N4M5
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100549888
gene id: 9103:LOC100549888
uniprot id: G1NDS2
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

9103:YPEL5
gene id: 9103:YPEL5
uniprot id: A0A803YKS5
names: Similarity
messages: Belongs to the yippee family.

9103:CRYZ
gene id: 9103:CRYZ
uniprot id: G1NHT0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9103:LOC100549312
gene id: 9103:LOC100549312
uniprot id: G1NDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9103:OIP5
gene id: 9103:OIP5
uniprot id: G1NFA7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

9103:LOC100545134
gene id: 9103:LOC100545134
uniprot id: G1N1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Nucleus

9103:MITF
gene id: 9103:MITF
uniprot id: G1NB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

9103:BCL7B
gene id: 9103:BCL7B
uniprot id: G1MR22
names: Similarity
messages: Belongs to the BCL7 family.

9103:AURKAIP1
gene id: 9103:AURKAIP1
uniprot id: G1MV33
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

9103:RPA1
gene id: 9103:RPA1
uniprot id: G1N189
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

9103:NECAP1
gene id: 9103:NECAP1
uniprot id: G1NMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9103:CCDC107
gene id: 9103:CCDC107
uniprot id: G1NEC0
names: Similarity
messages: Belongs to the ric-3 family.

9103:RYR3
gene id: 9103:RYR3
uniprot id: B4XW98
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9103:MGAT5
gene id: 9103:MGAT5
uniprot id: G1NII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

9103:CALHM2
gene id: 9103:CALHM2
uniprot id: G1NDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9103:ZPR1
gene id: 9103:ZPR1
uniprot id: A0A803XYX6
names: Similarity
messages: Belongs to the ZPR1 family.

9103:MTRF1
gene id: 9103:MTRF1
uniprot id: G1NQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9103:PCYT2
gene id: 9103:PCYT2
uniprot id: A0A803YM84
names: Similarity
messages: Belongs to the cytidylyltransferase family.

9103:METTL15
gene id: 9103:METTL15
uniprot id: A0A803YIG7
uniprot id: G1MS79
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

9103:LOC100541107
gene id: 9103:LOC100541107
uniprot id: G1N3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9103:ADGRL2
gene id: 9103:ADGRL2
uniprot id: A0A803Y8H4
names: Subcellular Location Annotation
messages: Membrane

9103:CZH18orf25
gene id: 9103:CZH18orf25
uniprot id: A0A803XM29
names: Subcellular Location Annotation
messages: Nucleus

9103:ABR
gene id: 9103:ABR
uniprot id: G1N407
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

9103:B3GALT2
gene id: 9103:B3GALT2
uniprot id: G1NQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:FAM160B1
gene id: 9103:FAM160B1
uniprot id: A0A803XS78
names: Similarity
messages: Belongs to the FHIP family.

9103:LOC100303663
gene id: 9103:LOC100303663
uniprot id: Q90X50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:PPP4R3A
gene id: 9103:PPP4R3A
uniprot id: G1NK92
names: Similarity
messages: Belongs to the SMEK family.

9103:SV2B
gene id: 9103:SV2B
uniprot id: G1N9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

9103:LOC100545437
gene id: 9103:LOC100545437
uniprot id: G1N570
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:LOC104914240
gene id: 9103:LOC104914240
uniprot id: G1MUZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GPAT4
gene id: 9103:GPAT4
uniprot id: G1MWM2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9103:TRPV4
gene id: 9103:TRPV4
uniprot id: G1N3R5
names: Subcellular Location Annotation
messages: Membrane

9103:GYS2
gene id: 9103:GYS2
uniprot id: A0A803XMA9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

9103:FZD6
gene id: 9103:FZD6
uniprot id: G1NIC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:LOC100549427
gene id: 9103:LOC100549427
uniprot id: G1N492
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:SERPINB14
gene id: 9103:SERPINB14
uniprot id: G1MYL1
uniprot id: O73860
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the serpin family.
messages: Belongs to the serpin family. Ov-serpin subfamily.
messages: Major protein of egg white.
messages: Secreted
messages: Storage protein of egg white. Lack protease inhibitory activity (By similarity).
messages: The signal sequence is not cleaved. The functional signal for membrane translocation of ovalbumin becomes accessible when the nascent chain is 50 to 60 residues long. The hydrophobic sequence which lies between residues 27 and 43 folds back on the preceding residues to form an amphipathic hairpin structure which is the signal element recognized by the membrane (By similarity).

9103:APOA1
gene id: 9103:APOA1
uniprot id: G1MVX1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9103:LOC100550268
gene id: 9103:LOC100550268
uniprot id: G3USZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Membrane

9103:LOC100544279
gene id: 9103:LOC100544279
uniprot id: G1NKE9
names: Subcellular Location Annotation
messages: Secreted

9103:UTP3
gene id: 9103:UTP3
uniprot id: G1NC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAS10 family.
messages: nucleolus

9103:KCNA4
gene id: 9103:KCNA4
uniprot id: A0A803YRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

9103:LRP8
gene id: 9103:LRP8
uniprot id: A0A803XSU4
uniprot id: G1NFK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TRAPPC3
gene id: 9103:TRAPPC3
uniprot id: G1MXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9103:CCNG1
gene id: 9103:CCNG1
uniprot id: G1MUL0
names: Similarity
messages: Belongs to the cyclin family.

9103:SMIM12
gene id: 9103:SMIM12
uniprot id: G1NRI8
names: Similarity
messages: Belongs to the SMIM12 family.

9103:SHQ1
gene id: 9103:SHQ1
uniprot id: A0A803Y4M4
names: Similarity
messages: Belongs to the SHQ1 family.

9103:HS3ST5
gene id: 9103:HS3ST5
uniprot id: G1NL03
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:AIF1L
gene id: 9103:AIF1L
uniprot id: A0A803Y4R3
names: Subcellular Location Annotation
messages: ruffle membrane

9103:LDHB
gene id: 9103:LDHB
uniprot id: G1NLS0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9103:KCNE3
gene id: 9103:KCNE3
uniprot id: A0A803YHD9
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9103:WSCD1
gene id: 9103:WSCD1
uniprot id: G1N952
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

9103:PHB
gene id: 9103:PHB
uniprot id: G1MU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

9103:VASN
gene id: 9103:VASN
uniprot id: G1NAX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GPRIN3
gene id: 9103:GPRIN3
uniprot id: G1NSA0
names: Function
messages: May be involved in neurite outgrowth.

9103:NDUFS1
gene id: 9103:NDUFS1
uniprot id: G1N8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

9103:CFI
gene id: 9103:CFI
uniprot id: G1NEZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TGM4
gene id: 9103:TGM4
uniprot id: G1NGK7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9103:ITIH5
gene id: 9103:ITIH5
uniprot id: G1MYQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9103:GIMD1
gene id: 9103:GIMD1
uniprot id: G1N2J4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9103:LOC100303688
gene id: 9103:LOC100303688
uniprot id: Q9PT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

9103:VAMP7
gene id: 9103:VAMP7
uniprot id: G1N185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9103:LOC100541644
gene id: 9103:LOC100541644
uniprot id: H9H1Y9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9103:CCT2
gene id: 9103:CCT2
uniprot id: G1NPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9103:TXLNB
gene id: 9103:TXLNB
uniprot id: G1NL02
names: Similarity
messages: Belongs to the taxilin family.

9103:ND5
gene id: 9103:ND5
uniprot id: A9XBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9103:FICD
gene id: 9103:FICD
uniprot id: G1N250
names: Similarity
messages: Belongs to the fic family.

9103:LOC100547762
gene id: 9103:LOC100547762
uniprot id: G1MSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9103:SPINK2
gene id: 9103:SPINK2
uniprot id: Q5GMQ7
names: Subcellular Location Annotation
messages: Secreted

9103:GABRA2
gene id: 9103:GABRA2
uniprot id: G1NHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

9103:OLAH
gene id: 9103:OLAH
uniprot id: G1N829
names: Similarity
messages: Belongs to the thioesterase family.

9103:APOA4
gene id: 9103:APOA4
uniprot id: G1MVV8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9103:EEF1D
gene id: 9103:EEF1D
uniprot id: G1NK44
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

9103:SH3PXD2A
gene id: 9103:SH3PXD2A
uniprot id: A0A803XVS5
uniprot id: A0A803Y367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

9103:LOC100541523
gene id: 9103:LOC100541523
uniprot id: A0A803YFD3
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9103:HMBS
gene id: 9103:HMBS
uniprot id: A0A803YKM5
uniprot id: G1MWI3
names: Similarity
messages: Belongs to the HMBS family.

9103:LOC100541404
gene id: 9103:LOC100541404
uniprot id: G1N4U2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9103:TGFB2
gene id: 9103:TGFB2
uniprot id: G1NAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

9103:PYGL
gene id: 9103:PYGL
uniprot id: G1NLY5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

9103:IRF7
gene id: 9103:IRF7
uniprot id: G1NA74
names: Subcellular Location Annotation
messages: Nucleus

9103:TAF12
gene id: 9103:TAF12
uniprot id: G1MSE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

9103:CD320
gene id: 9103:CD320
uniprot id: A0A803XRC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TRAF5
gene id: 9103:TRAF5
uniprot id: G1NBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9103:ATP6AP2
gene id: 9103:ATP6AP2
uniprot id: G3US21
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

9103:LOC109367286
gene id: 9103:LOC109367286
uniprot id: G1NDH6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:LOC100547695
gene id: 9103:LOC100547695
uniprot id: G1N9R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

9103:ORMDL1
gene id: 9103:ORMDL1
uniprot id: G1N382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9103:AGTR1
gene id: 9103:AGTR1
uniprot id: P33396
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Adrenal medulla.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: C-terminal Ser or Thr residues may be phosphorylated.
messages: Cell membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

9103:MALSU1
gene id: 9103:MALSU1
uniprot id: G1NDG8
names: Similarity
messages: Belongs to the Iojap/RsfS family.

9103:CMC4
gene id: 9103:CMC4
uniprot id: A0A803YCB5
names: Similarity
messages: Belongs to the CMC4 family.

9103:CRYBG1
gene id: 9103:CRYBG1
uniprot id: A0A803XVY5
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9103:COG4
gene id: 9103:COG4
uniprot id: G1MS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

9103:MBTPS1
gene id: 9103:MBTPS1
uniprot id: G1MQ93
names: Similarity
messages: Belongs to the peptidase S8 family.

9103:BRD1
gene id: 9103:BRD1
uniprot id: A0A803XZW3
uniprot id: A0A803YCW8
names: Subcellular Location Annotation
messages: Nucleus

9103:EIF2S2
gene id: 9103:EIF2S2
uniprot id: A0A803XYY6
uniprot id: A0A803YLQ2
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

9103:AGMAT
gene id: 9103:AGMAT
uniprot id: G1N1M7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

9103:FBXO25
gene id: 9103:FBXO25
uniprot id: A0A803XWE8
uniprot id: A0A803XXZ7
names: Subcellular Location Annotation
messages: Nucleus

9103:SRP9
gene id: 9103:SRP9
uniprot id: G1N7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

9103:TRPM2
gene id: 9103:TRPM2
uniprot id: G1MY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

9103:S100B
gene id: 9103:S100B
uniprot id: G1MRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9103:SFRP5
gene id: 9103:SFRP5
uniprot id: G1NBK0
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CHRNA4
gene id: 9103:CHRNA4
uniprot id: G1N3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:PGM5
gene id: 9103:PGM5
uniprot id: G3UTT2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9103:ATG3
gene id: 9103:ATG3
uniprot id: G1NNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

9103:DCAF13
gene id: 9103:DCAF13
uniprot id: G1NIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

9103:LOC100546233
gene id: 9103:LOC100546233
uniprot id: G1NLN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

9103:UBA5
gene id: 9103:UBA5
uniprot id: G1NG60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

9103:LOC104913878
gene id: 9103:LOC104913878
uniprot id: A0A803Y2J4
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9103:SLC30A6
gene id: 9103:SLC30A6
uniprot id: G1NFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9103:CXXC5
gene id: 9103:CXXC5
uniprot id: G1MVL5
names: Subcellular Location Annotation
messages: Cytoplasm

9103:RELL2
gene id: 9103:RELL2
uniprot id: G1MT62
names: Similarity
messages: Belongs to the RELT family.

9103:TGFBR2
gene id: 9103:TGFBR2
uniprot id: G1NF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

9103:WDR3
gene id: 9103:WDR3
uniprot id: G1NN59
names: Subcellular Location Annotation
messages: nucleolus

9103:CCR6
gene id: 9103:CCR6
uniprot id: G1NRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

9103:SEMA6A
gene id: 9103:SEMA6A
uniprot id: A0A803XSM9
uniprot id: A0A803YJY8
uniprot id: A0A803YLW7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TCP11L2
gene id: 9103:TCP11L2
uniprot id: G1NJQ5
names: Similarity
messages: Belongs to the TCP11 family.

9103:YIPF5
gene id: 9103:YIPF5
uniprot id: G1NAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9103:GALR2
gene id: 9103:GALR2
uniprot id: G1MYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9103:TAF7L
gene id: 9103:TAF7L
uniprot id: G1NAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9103:LOC100539712
gene id: 9103:LOC100539712
uniprot id: G1MU70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9103:LYVE1
gene id: 9103:LYVE1
uniprot id: G1N2P7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:FOXL3
gene id: 9103:FOXL3
uniprot id: G3UV78
names: Subcellular Location Annotation
messages: Nucleus

9103:PTPN6
gene id: 9103:PTPN6
uniprot id: A0A803YLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

9103:LOC100544098
gene id: 9103:LOC100544098
uniprot id: G1MVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

9103:ALAS1
gene id: 9103:ALAS1
uniprot id: G1MW13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

9103:LOC104911959
gene id: 9103:LOC104911959
uniprot id: A0A803Y0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9103:MMP7
gene id: 9103:MMP7
uniprot id: G3UV36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9103:XPOT
gene id: 9103:XPOT
uniprot id: G1NCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

9103:PRICKLE1
gene id: 9103:PRICKLE1
uniprot id: G1NB00
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9103:GCNT4
gene id: 9103:GCNT4
uniprot id: G1N079
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9103:MIS12
gene id: 9103:MIS12
uniprot id: G3UT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

9103:NPY5R
gene id: 9103:NPY5R
uniprot id: G3UTD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

9103:RIC8A
gene id: 9103:RIC8A
uniprot id: G1MU59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

9103:LOC100542633
gene id: 9103:LOC100542633
uniprot id: G1NFP4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9103:TPD52
gene id: 9103:TPD52
uniprot id: A0A803Y123
names: Similarity
messages: Belongs to the TPD52 family.

9103:CMTM4
gene id: 9103:CMTM4
uniprot id: A0A803YQU8
names: Subcellular Location Annotation
messages: Membrane

9103:GDPD2
gene id: 9103:GDPD2
uniprot id: G1MU66
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9103:IRX1
gene id: 9103:IRX1
uniprot id: A0A803XMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9103:CD81
gene id: 9103:CD81
uniprot id: G1N786
names: Subcellular Location Annotation
messages: Membrane

9103:CDK2AP1
gene id: 9103:CDK2AP1
uniprot id: G1MWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

9103:LOC104909200
gene id: 9103:LOC104909200
uniprot id: G1MQS3
uniprot id: G1MSP2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9103:CNGA3
gene id: 9103:CNGA3
uniprot id: G1NPJ4
names: Subcellular Location Annotation
messages: Membrane

9103:SKAP2
gene id: 9103:SKAP2
uniprot id: A0A803XSV2
uniprot id: A0A803YKF5
names: Similarity
messages: Belongs to the SKAP family.

9103:LOC100546034
gene id: 9103:LOC100546034
uniprot id: A0A803XK14
names: Subcellular Location Annotation
messages: Membrane

9103:CCNE2
gene id: 9103:CCNE2
uniprot id: G1NHN0
names: Similarity
messages: Belongs to the cyclin family.

9103:STAMBPL1
gene id: 9103:STAMBPL1
uniprot id: G1N887
names: Similarity
messages: Belongs to the peptidase M67C family.

9103:OSBPL3
gene id: 9103:OSBPL3
uniprot id: G1NDS6
names: Similarity
messages: Belongs to the OSBP family.

9103:LOC100539813
gene id: 9103:LOC100539813
uniprot id: G1NED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9103:OPRK1
gene id: 9103:OPRK1
uniprot id: G1NEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

9103:LOC100538367
gene id: 9103:LOC100538367
uniprot id: G1NKG9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:CA10
gene id: 9103:CA10
uniprot id: A0A803YG02
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

9103:TNFSF8
gene id: 9103:TNFSF8
uniprot id: G3UUJ3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9103:LOC100548173
gene id: 9103:LOC100548173
uniprot id: G1NNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:RBP2
gene id: 9103:RBP2
uniprot id: G1MZ01
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:MINAR1
gene id: 9103:MINAR1
uniprot id: A0A803YLM7
names: Similarity
messages: Belongs to the MINAR family.

9103:FAM110C
gene id: 9103:FAM110C
uniprot id: A0A803XRW2
names: Similarity
messages: Belongs to the FAM110 family.

9103:LOC104914419
gene id: 9103:LOC104914419
uniprot id: H9H2F7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

9103:LOC100541781
gene id: 9103:LOC100541781
uniprot id: G1NH10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:SLC2A8
gene id: 9103:SLC2A8
uniprot id: G1N9B3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9103:AP1M1
gene id: 9103:AP1M1
uniprot id: G1N243
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

9103:KIF23
gene id: 9103:KIF23
uniprot id: A0A803YA13
uniprot id: G5E7T7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:DHX8
gene id: 9103:DHX8
uniprot id: G1MU21
names: Subcellular Location Annotation
messages: Nucleus

9103:CAMK2D
gene id: 9103:CAMK2D
uniprot id: A0A803YR93
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9103:LGMN
gene id: 9103:LGMN
uniprot id: A0A803YI36
names: Similarity
messages: Belongs to the peptidase C13 family.

9103:CCND2
gene id: 9103:CCND2
uniprot id: G1NM89
names: Similarity
messages: Belongs to the cyclin family.

9103:CCT8
gene id: 9103:CCT8
uniprot id: A0A803XTM3
uniprot id: G1NNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

9103:WDFY2
gene id: 9103:WDFY2
uniprot id: G1NQ68
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9103:CP
gene id: 9103:CP
uniprot id: A0A803YMC9
names: Similarity
messages: Belongs to the multicopper oxidase family.

9103:ERG
gene id: 9103:ERG
uniprot id: A0A803YJ32
uniprot id: G1NNZ0
uniprot id: G3UT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:LOC100543795
gene id: 9103:LOC100543795
uniprot id: A0A803YGR5
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

9103:SUSD1
gene id: 9103:SUSD1
uniprot id: A0A803YJ29
uniprot id: G1N8M3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GDNF
gene id: 9103:GDNF
uniprot id: G1MWC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9103:RXRG
gene id: 9103:RXRG
uniprot id: A0A803Y8E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

9103:LOC100541865
gene id: 9103:LOC100541865
uniprot id: A0A803Y2D4
names: Subunit
messages: Monomer.

9103:LOC104912373
gene id: 9103:LOC104912373
uniprot id: G1NLN6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:LOC100546297
gene id: 9103:LOC100546297
uniprot id: A0A803XYI5
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9103:STX11
gene id: 9103:STX11
uniprot id: G1NRS1
names: Similarity
messages: Belongs to the syntaxin family.

9103:CPEB4
gene id: 9103:CPEB4
uniprot id: G1MX60
names: Similarity
messages: Belongs to the RRM CPEB family.

9103:PITX2
gene id: 9103:PITX2
uniprot id: A0A803Y5J7
uniprot id: A0A803YRT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9103:LOC100543786
gene id: 9103:LOC100543786
uniprot id: G1NAG4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9103:LOC100548057
gene id: 9103:LOC100548057
uniprot id: A0A803YIR2
uniprot id: G1MXJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

9103:ATPSCKMT
gene id: 9103:ATPSCKMT
uniprot id: G1N388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

9103:LOC104909416
gene id: 9103:LOC104909416
uniprot id: G1NQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9103:LOC100549995
gene id: 9103:LOC100549995
uniprot id: G1NR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:WARS1
gene id: 9103:WARS1
uniprot id: G1NKU2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9103:IMP4
gene id: 9103:IMP4
uniprot id: G1MQ28
names: Subcellular Location Annotation
messages: nucleolus

9103:MTNR1A
gene id: 9103:MTNR1A
uniprot id: G1NG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:MCL1
gene id: 9103:MCL1
uniprot id: G1MPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: nucleoplasm

9103:FAM83B
gene id: 9103:FAM83B
uniprot id: G1NMB5
names: Similarity
messages: Belongs to the FAM83 family.

9103:LOC100544462
gene id: 9103:LOC100544462
uniprot id: G1N6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

9103:LOC100541944
gene id: 9103:LOC100541944
uniprot id: A0A803XLW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9103:DHRS7C
gene id: 9103:DHRS7C
uniprot id: H9H2L1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:NARF
gene id: 9103:NARF
uniprot id: G1MXE6
names: Similarity
messages: Belongs to the NARF family.

9103:MRPS17
gene id: 9103:MRPS17
uniprot id: G1MYR0
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

9103:LOC104914407
gene id: 9103:LOC104914407
uniprot id: A0A803YJ48
names: Subcellular Location Annotation
messages: Membrane

9103:GPX7
gene id: 9103:GPX7
uniprot id: G1NFC2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9103:HSF2
gene id: 9103:HSF2
uniprot id: A0A803YSG8
uniprot id: G1NKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9103:SPC25
gene id: 9103:SPC25
uniprot id: G1NDU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9103:KCNG1
gene id: 9103:KCNG1
uniprot id: G1NAS5
names: Subcellular Location Annotation
messages: Membrane

9103:PPIL6
gene id: 9103:PPIL6
uniprot id: G1NL67
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9103:ELOVL2
gene id: 9103:ELOVL2
uniprot id: G1MWP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9103:STMN2
gene id: 9103:STMN2
uniprot id: G1NGF3
names: Similarity
messages: Belongs to the stathmin family.

9103:C4H4orf47
gene id: 9103:C4H4orf47
uniprot id: G1NFV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

9103:BRCC3
gene id: 9103:BRCC3
uniprot id: G1NA48
names: Similarity
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.

9103:LOC104909313
gene id: 9103:LOC104909313
uniprot id: G1NGB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:C6H7orf25
gene id: 9103:C6H7orf25
uniprot id: G1NRV1
names: Similarity
messages: Belongs to the UPF0415 family.

9103:POLR2L
gene id: 9103:POLR2L
uniprot id: G1NGE6
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

9103:PPP1R1C
gene id: 9103:PPP1R1C
uniprot id: G1NA38
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9103:SSRP1
gene id: 9103:SSRP1
uniprot id: G1NBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

9103:CNDP1
gene id: 9103:CNDP1
uniprot id: G1N7V9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9103:EML1
gene id: 9103:EML1
uniprot id: A0A803Y6C7
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

9103:EMP2
gene id: 9103:EMP2
uniprot id: G1N8I8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

9103:LOC100544139
gene id: 9103:LOC100544139
uniprot id: A0A803XZ30
uniprot id: G1NAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:IQSEC3
gene id: 9103:IQSEC3
uniprot id: G1NKY8
names: Similarity
messages: Belongs to the BRAG family.

9103:TMEM230
gene id: 9103:TMEM230
uniprot id: G1MPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

9103:LOC100550045
gene id: 9103:LOC100550045
uniprot id: G1NRB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9103:SLC25A19
gene id: 9103:SLC25A19
uniprot id: A0A803XKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:CTSK
gene id: 9103:CTSK
uniprot id: G3X8J6
names: Similarity
messages: Belongs to the peptidase C1 family.

9103:LOC104914523
gene id: 9103:LOC104914523
uniprot id: A0A803Y140
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:CRB2
gene id: 9103:CRB2
uniprot id: A0A803YNA6
uniprot id: G1N7Z5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ID1
gene id: 9103:ID1
uniprot id: G1N5H6
names: Subcellular Location Annotation
messages: Nucleus

9103:SMIM18
gene id: 9103:SMIM18
uniprot id: A0A803XN25
names: Subcellular Location Annotation
messages: Membrane

9103:MID1
gene id: 9103:MID1
uniprot id: A0A803XQ03
names: Subcellular Location Annotation
messages: cytoskeleton

9103:WNT3
gene id: 9103:WNT3
uniprot id: G3UQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9103:SLC66A1
gene id: 9103:SLC66A1
uniprot id: G1N1D6
names: Subcellular Location Annotation
messages: Membrane

9103:BCO1
gene id: 9103:BCO1
uniprot id: G1N4S4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

9103:SLC25A40
gene id: 9103:SLC25A40
uniprot id: G1N899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:P2RX5
gene id: 9103:P2RX5
uniprot id: G1N487
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9103:LOC100547060
gene id: 9103:LOC100547060
uniprot id: G1NAU2
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

9103:SLC11A1
gene id: 9103:SLC11A1
uniprot id: G1NG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

9103:MELTF
gene id: 9103:MELTF
uniprot id: G3UQM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

9103:MPPED2
gene id: 9103:MPPED2
uniprot id: G1MS47
names: Similarity
messages: Belongs to the UPF0046 family.

9103:VPS36
gene id: 9103:VPS36
uniprot id: G1NQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

9103:GSTA1.3
gene id: 9103:GSTA1.3
uniprot id: A0A803YD55
uniprot id: C8BLR3
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9103:DDX24
gene id: 9103:DDX24
uniprot id: G1NKG0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9103:RMND1
gene id: 9103:RMND1
uniprot id: G1NJ72
names: Similarity
messages: Belongs to the RMD1/sif2 family.

9103:KCNS1
gene id: 9103:KCNS1
uniprot id: G1MWS8
names: Subcellular Location Annotation
messages: Membrane

9103:LOC109369088
gene id: 9103:LOC109369088
uniprot id: A0A803YJI0
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

9103:ATP5F1A
gene id: 9103:ATP5F1A
uniprot id: G1NC68
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9103:YTHDF1
gene id: 9103:YTHDF1
uniprot id: A0A803XU66
uniprot id: G1N370
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

9103:CMAS
gene id: 9103:CMAS
uniprot id: G1NLN5
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

9103:HENMT1
gene id: 9103:HENMT1
uniprot id: G1N390
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

9103:DOK3
gene id: 9103:DOK3
uniprot id: G1MY17
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

9103:BTG4
gene id: 9103:BTG4
uniprot id: G1MXG8
names: Similarity
messages: Belongs to the BTG family.

9103:FLNB
gene id: 9103:FLNB
uniprot id: A0A803Y558
uniprot id: A0A803YJP2
uniprot id: G1N4G8
uniprot id: G3URL1
names: Similarity
messages: Belongs to the filamin family.

9103:LOC100544032
gene id: 9103:LOC100544032
uniprot id: G1MWU5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9103:GLOD4
gene id: 9103:GLOD4
uniprot id: G1N587
names: Similarity
messages: Belongs to the glyoxalase I family.

9103:LOC100541854
gene id: 9103:LOC100541854
uniprot id: G1N604
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9103:GABRA5
gene id: 9103:GABRA5
uniprot id: G1NPJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:ST8SIA2
gene id: 9103:ST8SIA2
uniprot id: A0A803Y8I2
uniprot id: G1N9U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:LAMC3
gene id: 9103:LAMC3
uniprot id: G1N1S6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9103:ABCG4
gene id: 9103:ABCG4
uniprot id: G1MUP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9103:RNF20
gene id: 9103:RNF20
uniprot id: A0A803XTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

9103:MYO1D
gene id: 9103:MYO1D
uniprot id: A0A803Y3F5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:LOC100540643
gene id: 9103:LOC100540643
uniprot id: G1MRE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GDF9
gene id: 9103:GDF9
uniprot id: G1NA80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

9103:ADAM19
gene id: 9103:ADAM19
uniprot id: G1N0L1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:AMER3
gene id: 9103:AMER3
uniprot id: G1MQP4
names: Similarity
messages: Belongs to the Amer family.

9103:FARS2
gene id: 9103:FARS2
uniprot id: A0A803Y5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

9103:LRRC8B
gene id: 9103:LRRC8B
uniprot id: G1N8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9103:THYN1
gene id: 9103:THYN1
uniprot id: G1MS60
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9103:TUBGCP3
gene id: 9103:TUBGCP3
uniprot id: G1NPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9103:XIAP
gene id: 9103:XIAP
uniprot id: A0A803YET2
uniprot id: A0A803YNK5
names: Similarity
messages: Belongs to the IAP family.

9103:AMZ1
gene id: 9103:AMZ1
uniprot id: G1MVC9
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

9103:LOC100548761
gene id: 9103:LOC100548761
uniprot id: A0A803YMP6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9103:TNFSF13B
gene id: 9103:TNFSF13B
uniprot id: G1NPT6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9103:ADGRG1
gene id: 9103:ADGRG1
uniprot id: A0A803YCL8
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane raft
messages: Secreted

9103:RPL13
gene id: 9103:RPL13
uniprot id: G1N7K0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

9103:SGF29
gene id: 9103:SGF29
uniprot id: G1NHX9
names: Subcellular Location Annotation
messages: Nucleus

9103:LRRC8A
gene id: 9103:LRRC8A
uniprot id: G1MZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9103:LOC104913875
gene id: 9103:LOC104913875
uniprot id: G1MT64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9103:MYO19
gene id: 9103:MYO19
uniprot id: G1N749
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:INPP4A
gene id: 9103:INPP4A
uniprot id: A0A803XLQ0
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

9103:HMGB2
gene id: 9103:HMGB2
uniprot id: G1N4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9103:CPT1A
gene id: 9103:CPT1A
uniprot id: G1NAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

9103:GABPA
gene id: 9103:GABPA
uniprot id: G1NNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:GJC2
gene id: 9103:GJC2
uniprot id: A0A803YC75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9103:PRMT7
gene id: 9103:PRMT7
uniprot id: G1MXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

9103:RPSA
gene id: 9103:RPSA
uniprot id: G1NGU2
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

9103:CPXM2
gene id: 9103:CPXM2
uniprot id: G1NGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9103:CAPN15
gene id: 9103:CAPN15
uniprot id: G1NCL4
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:ESS2
gene id: 9103:ESS2
uniprot id: G1N5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

9103:PAQR3
gene id: 9103:PAQR3
uniprot id: G1N5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9103:FAM160A1
gene id: 9103:FAM160A1
uniprot id: G1MYL4
names: Similarity
messages: Belongs to the FHIP family.

9103:CCDC90B
gene id: 9103:CCDC90B
uniprot id: A0A803YS27
names: Similarity
messages: Belongs to the CCDC90 family.

9103:TDRD7
gene id: 9103:TDRD7
uniprot id: G1N9C0
names: Subcellular Location Annotation
messages: Cytoplasm

9103:RPS6KA2
gene id: 9103:RPS6KA2
uniprot id: G1NI96
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

9103:PLA1A
gene id: 9103:PLA1A
uniprot id: A0A803XQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9103:LOC100550016
gene id: 9103:LOC100550016
uniprot id: G1NHE1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9103:LOC100541793
gene id: 9103:LOC100541793
uniprot id: A0A803XUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9103:BROX
gene id: 9103:BROX
uniprot id: G1N9P8
names: Similarity
messages: Belongs to the BROX family.

9103:INTS13
gene id: 9103:INTS13
uniprot id: G1NLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

9103:SLC16A5
gene id: 9103:SLC16A5
uniprot id: G1NAS3
names: Subcellular Location Annotation
messages: Membrane

9103:NCF2
gene id: 9103:NCF2
uniprot id: A0A803XQE6
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

9103:ECHDC2
gene id: 9103:ECHDC2
uniprot id: G1NFE0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9103:LOC100544862
gene id: 9103:LOC100544862
uniprot id: G1NEY4
names: Similarity
messages: Belongs to the intermediate filament family.

9103:CDK10
gene id: 9103:CDK10
uniprot id: G1N7X1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:CDC42
gene id: 9103:CDC42
uniprot id: G1N4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

9103:TMEM39B
gene id: 9103:TMEM39B
uniprot id: G1MZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

9103:LOC100540103
gene id: 9103:LOC100540103
uniprot id: G1N7N4
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CLCN4
gene id: 9103:CLCN4
uniprot id: G1NPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

9103:LOC100541755
gene id: 9103:LOC100541755
uniprot id: A0A803Y8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

9103:LOC100544448
gene id: 9103:LOC100544448
uniprot id: G1N558
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:MYCL
gene id: 9103:MYCL
uniprot id: G1N1S7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

9103:MTMR4
gene id: 9103:MTMR4
uniprot id: A0A803YNQ0
uniprot id: G1MT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

9103:FGA
gene id: 9103:FGA
uniprot id: G1MRL1
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9103:SLC25A20
gene id: 9103:SLC25A20
uniprot id: G1N946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:PCSK7
gene id: 9103:PCSK7
uniprot id: A0A803YR38
names: Similarity
messages: Belongs to the peptidase S8 family.

9103:DTYMK
gene id: 9103:DTYMK
uniprot id: A0A803YH47
names: Similarity
messages: Belongs to the thymidylate kinase family.

9103:LOC100545053
gene id: 9103:LOC100545053
uniprot id: A0A803XN99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:BTBD10
gene id: 9103:BTBD10
uniprot id: G1N179
names: Subcellular Location Annotation
messages: Cytoplasm

9103:CDKL1
gene id: 9103:CDKL1
uniprot id: G1NLV2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:LOC100546656
gene id: 9103:LOC100546656
uniprot id: A0A803YMR2
names: Similarity
messages: Belongs to the CCSER family.

9103:LOC100539820
gene id: 9103:LOC100539820
uniprot id: G1NFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

9103:CHCHD4
gene id: 9103:CHCHD4
uniprot id: A0A803YJB1
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

9103:CAPN10
gene id: 9103:CAPN10
uniprot id: A0A803XUN3
uniprot id: G1N9E1
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:LOC100541189
gene id: 9103:LOC100541189
uniprot id: G1NF01
names: Similarity
messages: Belongs to the FAM98 family.

9103:FAS
gene id: 9103:FAS
uniprot id: G1N8D3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

9103:CPLX3
gene id: 9103:CPLX3
uniprot id: G1MU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9103:SEPHS1
gene id: 9103:SEPHS1
uniprot id: G1N034
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

9103:CMKLR1
gene id: 9103:CMKLR1
uniprot id: G1NR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9103:LOC100541131
gene id: 9103:LOC100541131
uniprot id: G1NNG1
names: Similarity
messages: Belongs to the intercrine gamma family.

9103:ZNF711
gene id: 9103:ZNF711
uniprot id: G1MZJ4
names: Subcellular Location Annotation
messages: Nucleus

9103:TIRAP
gene id: 9103:TIRAP
uniprot id: A0A803XKY1
uniprot id: G1MQ01
uniprot id: G1MQ03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane

9103:LOC100543589
gene id: 9103:LOC100543589
uniprot id: A0A803XS83
uniprot id: G1MRG2
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9103:LOC100544252
gene id: 9103:LOC100544252
uniprot id: A0A803YNR1
uniprot id: G1MSV1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9103:SLC13A3
gene id: 9103:SLC13A3
uniprot id: G1MYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9103:IMMP1L
gene id: 9103:IMMP1L
uniprot id: G1MS34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

9103:LOC100549326
gene id: 9103:LOC100549326
uniprot id: A0A803Y0F3
uniprot id: G1NET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9103:EZH1
gene id: 9103:EZH1
uniprot id: G1MY19
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100540180
gene id: 9103:LOC100540180
uniprot id: A0A803XSJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

9103:LOC100546734
gene id: 9103:LOC100546734
uniprot id: G1MQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9103:WTAP
gene id: 9103:WTAP
uniprot id: G1NIQ5
names: Similarity
messages: Belongs to the fl(2)d family.

9103:LOC100539142
gene id: 9103:LOC100539142
uniprot id: G1MUE2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9103:CPS1
gene id: 9103:CPS1
uniprot id: G1MY12
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CRIPT
gene id: 9103:CRIPT
uniprot id: A0A803YBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

9103:PWWP3A
gene id: 9103:PWWP3A
uniprot id: A0A803XMD2
names: Similarity
messages: Belongs to the PWWP3A family.

9103:SYT2
gene id: 9103:SYT2
uniprot id: G1MS64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

9103:IL18R1
gene id: 9103:IL18R1
uniprot id: G1NPN1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9103:LOC100546675
gene id: 9103:LOC100546675
uniprot id: A0A803Y9L1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

9103:GABRB2
gene id: 9103:GABRB2
uniprot id: G3UNX7
uniprot id: G3UPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:RABGGTB
gene id: 9103:RABGGTB
uniprot id: G1NHW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

9103:GTF2E1
gene id: 9103:GTF2E1
uniprot id: G1NN89
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

9103:GRIK3
gene id: 9103:GRIK3
uniprot id: G1MWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9103:SLAIN2
gene id: 9103:SLAIN2
uniprot id: G1NHE4
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

9103:GJA5
gene id: 9103:GJA5
uniprot id: A0A803YMW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9103:CSK
gene id: 9103:CSK
uniprot id: G1MU24
uniprot id: G3UP76
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9103:MED7
gene id: 9103:MED7
uniprot id: G1NR47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

9103:TOB2
gene id: 9103:TOB2
uniprot id: G1NRJ4
names: Similarity
messages: Belongs to the BTG family.

9103:SCOC
gene id: 9103:SCOC
uniprot id: G1MVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

9103:ACO1
gene id: 9103:ACO1
uniprot id: G1N9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

9103:IFNG
gene id: 9103:IFNG
uniprot id: G1NDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
messages: Secreted

9103:CXCR5
gene id: 9103:CXCR5
uniprot id: A0A803YHX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:CTDP1
gene id: 9103:CTDP1
uniprot id: A0A803XR93
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

9103:CDKN3
gene id: 9103:CDKN3
uniprot id: A0A803XMH9
uniprot id: G1NLR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

9103:KCNK3
gene id: 9103:KCNK3
uniprot id: G3UQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9103:ARHGEF3
gene id: 9103:ARHGEF3
uniprot id: A0A803YEW9
uniprot id: A0A803YMX0
uniprot id: G1N3B4
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

9103:MIGA2
gene id: 9103:MIGA2
uniprot id: G1N030
names: Similarity
messages: Belongs to the mitoguardin family.

9103:RNFT1
gene id: 9103:RNFT1
uniprot id: G1N6B4
names: Subcellular Location Annotation
messages: Membrane

9103:OSBPL1A
gene id: 9103:OSBPL1A
uniprot id: G1ND00
names: Similarity
messages: Belongs to the OSBP family.

9103:FAM13A
gene id: 9103:FAM13A
uniprot id: A0A803Y3E8
uniprot id: G1N184
names: Similarity
messages: Belongs to the FAM13 family.

9103:PDYN
gene id: 9103:PDYN
uniprot id: G1N556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

9103:CTNNBIP1
gene id: 9103:CTNNBIP1
uniprot id: G1MYC9
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9103:SH2B2
gene id: 9103:SH2B2
uniprot id: G1MWL7
names: Similarity
messages: Belongs to the SH2B adapter family.

9103:ZC3H12B
gene id: 9103:ZC3H12B
uniprot id: G1MQ08
names: Similarity
messages: Belongs to the ZC3H12 family.

9103:PLRG1
gene id: 9103:PLRG1
uniprot id: G1MRG5
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

9103:CPEB1
gene id: 9103:CPEB1
uniprot id: A0A803XTH2
uniprot id: G1MRN5
names: Similarity
messages: Belongs to the RRM CPEB family.

9103:MRPS33
gene id: 9103:MRPS33
uniprot id: G1NKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

9103:NIPAL4
gene id: 9103:NIPAL4
uniprot id: G1N0L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9103:PLAU
gene id: 9103:PLAU
uniprot id: G1N3G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:EIF2A
gene id: 9103:EIF2A
uniprot id: G1NEN3
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

9103:SNX10
gene id: 9103:SNX10
uniprot id: A0A803YGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9103:LOC100538984
gene id: 9103:LOC100538984
uniprot id: G1NGN2
names: Subcellular Location Annotation
messages: Membrane

9103:DGLUCY
gene id: 9103:DGLUCY
uniprot id: G1NK77
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

9103:SYF2
gene id: 9103:SYF2
uniprot id: G1MT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

9103:PDGFB
gene id: 9103:PDGFB
uniprot id: G1NL92
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9103:SYPL1
gene id: 9103:SYPL1
uniprot id: G1N4S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

9103:RAMAC
gene id: 9103:RAMAC
uniprot id: G1NS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

9103:HMOX2
gene id: 9103:HMOX2
uniprot id: G1NAF3
names: Similarity
messages: Belongs to the heme oxygenase family.

9103:TM9SF3
gene id: 9103:TM9SF3
uniprot id: A0A803XXB8
uniprot id: G3UP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9103:LOC100543527
gene id: 9103:LOC100543527
uniprot id: G1N619
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

9103:SEPTIN9
gene id: 9103:SEPTIN9
uniprot id: A0A803YAZ7
uniprot id: A0A803YS64
uniprot id: G1MXP0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9103:XRCC4
gene id: 9103:XRCC4
uniprot id: A0A803Y7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

9103:PITX3
gene id: 9103:PITX3
uniprot id: G1N5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9103:PRDX1
gene id: 9103:PRDX1
uniprot id: G1NDB7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9103:INTS9
gene id: 9103:INTS9
uniprot id: A0A803XS28
uniprot id: G1NN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

9103:ATP6V1C1
gene id: 9103:ATP6V1C1
uniprot id: G1NIA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9103:CPNE1
gene id: 9103:CPNE1
uniprot id: G1MSB0
names: Similarity
messages: Belongs to the copine family.

9103:LOC100545313
gene id: 9103:LOC100545313
uniprot id: A0A803Y1N9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:ETS1
gene id: 9103:ETS1
uniprot id: G1MQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

9103:NCAPG
gene id: 9103:NCAPG
uniprot id: G1NIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

9103:LOC100543282
gene id: 9103:LOC100543282
uniprot id: G1NRI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:EPHA5
gene id: 9103:EPHA5
uniprot id: G1NNL6
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100548849
gene id: 9103:LOC100548849
uniprot id: G1ND38
names: Subcellular Location Annotation
messages: Membrane

9103:INO80D
gene id: 9103:INO80D
uniprot id: G1N914
names: Subcellular Location Annotation
messages: Nucleus

9103:TBX20
gene id: 9103:TBX20
uniprot id: G1NHI6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9103:RPL27
gene id: 9103:RPL27
uniprot id: G1MYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

9103:LOC100550754
gene id: 9103:LOC100550754
uniprot id: G1N854
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9103:AQP8
gene id: 9103:AQP8
uniprot id: G1N3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9103:DCAF1
gene id: 9103:DCAF1
uniprot id: A0A803YFY4
uniprot id: G1MTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

9103:PDK4
gene id: 9103:PDK4
uniprot id: G1NBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

9103:SLC25A30
gene id: 9103:SLC25A30
uniprot id: G1NQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9103:LOC104913409
gene id: 9103:LOC104913409
uniprot id: G1NRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

9103:DSE
gene id: 9103:DSE
uniprot id: G1NKZ7
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9103:SLC6A12
gene id: 9103:SLC6A12
uniprot id: G1NL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9103:DTX1
gene id: 9103:DTX1
uniprot id: G1N1B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9103:LOC100542821
gene id: 9103:LOC100542821
uniprot id: A0A803Y0Z2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:CLUH
gene id: 9103:CLUH
uniprot id: G1N917
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

9103:CHRNA3
gene id: 9103:CHRNA3
uniprot id: G1MWZ2
uniprot id: G3UV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9103:GPX3
gene id: 9103:GPX3
uniprot id: M1EWH6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9103:ADRB3
gene id: 9103:ADRB3
uniprot id: P43141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB4C sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.
messages: Broad tissue distribution.
messages: Cell membrane

9103:LOC104912327
gene id: 9103:LOC104912327
uniprot id: G1N0F1
names: Similarity
messages: Belongs to the TMEM121 family.

9103:LOC100539160
gene id: 9103:LOC100539160
uniprot id: G1N716
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9103:CSGALNACT2
gene id: 9103:CSGALNACT2
uniprot id: A0A803XW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9103:NAB1
gene id: 9103:NAB1
uniprot id: G1N3F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

9103:RPS15
gene id: 9103:RPS15
uniprot id: G1MYH5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

9103:NDUFS6
gene id: 9103:NDUFS6
uniprot id: G1N5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

9103:DOT1L
gene id: 9103:DOT1L
uniprot id: G1MT95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Histone methyltransferase. Methylates 'Lys-79' of histone H3.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

9103:SEMA7A
gene id: 9103:SEMA7A
uniprot id: A0A803YJ66
uniprot id: G1MUM7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:MYF6
gene id: 9103:MYF6
uniprot id: D2KKK5
names: Subcellular Location Annotation
messages: Nucleus

9103:LRRC8C
gene id: 9103:LRRC8C
uniprot id: G1N8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9103:ACY1
gene id: 9103:ACY1
uniprot id: G1MXL7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

9103:ND1
gene id: 9103:ND1
uniprot id: A9XBD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

9103:LOC100547253
gene id: 9103:LOC100547253
uniprot id: A0A803XQ74
names: Similarity
messages: Belongs to the globin family.

9103:ADAMTS13
gene id: 9103:ADAMTS13
uniprot id: G1N475
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:LLPH
gene id: 9103:LLPH
uniprot id: G1NRH5
names: Similarity
messages: Belongs to the learning-associated protein family.

9103:EBNA1BP2
gene id: 9103:EBNA1BP2
uniprot id: G1NBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

9103:SPP2
gene id: 9103:SPP2
uniprot id: G1MUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

9103:LOC100545477
gene id: 9103:LOC100545477
uniprot id: G1NFH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:CDIP1
gene id: 9103:CDIP1
uniprot id: G1NAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

9103:PAPOLA
gene id: 9103:PAPOLA
uniprot id: A0A803YF92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9103:ANXA5
gene id: 9103:ANXA5
uniprot id: G1NDY6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9103:CLCN6
gene id: 9103:CLCN6
uniprot id: G1N3H1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NT5C2
gene id: 9103:NT5C2
uniprot id: A0A803XUX0
uniprot id: G1NDE4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

9103:KBTBD8
gene id: 9103:KBTBD8
uniprot id: A0A803YBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

9103:SEC61A1
gene id: 9103:SEC61A1
uniprot id: G1N5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC100541180
gene id: 9103:LOC100541180
uniprot id: H9H2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:EXOC3L4
gene id: 9103:EXOC3L4
uniprot id: G1NL01
names: Similarity
messages: Belongs to the SEC6 family.

9103:GPM6B
gene id: 9103:GPM6B
uniprot id: A0A803XS57
uniprot id: A0A803XSI3
uniprot id: A0A803Y9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9103:TEKT1
gene id: 9103:TEKT1
uniprot id: G1N9H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

9103:TMEM35A
gene id: 9103:TMEM35A
uniprot id: G1NAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

9103:IDH1
gene id: 9103:IDH1
uniprot id: G1N9S1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

9103:MC2R
gene id: 9103:MC2R
uniprot id: G1NRQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

9103:TRMT6
gene id: 9103:TRMT6
uniprot id: G1N6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

9103:DPH5
gene id: 9103:DPH5
uniprot id: G1N4Q3
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

9103:ANK1
gene id: 9103:ANK1
uniprot id: A0A803Y670
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9103:SLC2A12
gene id: 9103:SLC2A12
uniprot id: G1NKB4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9103:PNPLA1
gene id: 9103:PNPLA1
uniprot id: A0A803YFY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:SLC6A17
gene id: 9103:SLC6A17
uniprot id: G1MTV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9103:CAT
gene id: 9103:CAT
uniprot id: G1NCW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

9103:AS3MT
gene id: 9103:AS3MT
uniprot id: G1ND99
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

9103:DDOST
gene id: 9103:DDOST
uniprot id: G1N6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

9103:GPR107
gene id: 9103:GPR107
uniprot id: G1N122
names: Subcellular Location Annotation
messages: Membrane

9103:PLPBP
gene id: 9103:PLPBP
uniprot id: G1MSU6
names: Caution
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

9103:PJVK
gene id: 9103:PJVK
uniprot id: G1NB24
names: Similarity
messages: Belongs to the gasdermin family.

9103:TSPAN4
gene id: 9103:TSPAN4
uniprot id: A0A803YG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9103:LIMK1
gene id: 9103:LIMK1
uniprot id: G1MT52
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

9103:MAT2B
gene id: 9103:MAT2B
uniprot id: A0A803Y4N3
uniprot id: A0A803YJ92
uniprot id: G3US55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

9103:MYH11
gene id: 9103:MYH11
uniprot id: G1N5L2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:LOC104914035
gene id: 9103:LOC104914035
uniprot id: A0A803YFF6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9103:UTS2R
gene id: 9103:UTS2R
uniprot id: A0A803XYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

9103:LAMB1
gene id: 9103:LAMB1
uniprot id: G1NC71
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9103:SPTY2D1
gene id: 9103:SPTY2D1
uniprot id: G1N6D6
names: Similarity
messages: Belongs to the SPT2 family.

9103:CELF6
gene id: 9103:CELF6
uniprot id: A0A803XVX2
uniprot id: H9H0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

9103:SLC41A1
gene id: 9103:SLC41A1
uniprot id: G1MVU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9103:KCNMA1
gene id: 9103:KCNMA1
uniprot id: G3UQI3
uniprot id: G3UT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

9103:L3MBTL2
gene id: 9103:L3MBTL2
uniprot id: G1NHY9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
messages: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

9103:CCT5
gene id: 9103:CCT5
uniprot id: A0A803YE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9103:CTNS
gene id: 9103:CTNS
uniprot id: G1N4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

9103:LOC100550291
gene id: 9103:LOC100550291
uniprot id: A0A803XT57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9103:RAN
gene id: 9103:RAN
uniprot id: G1MTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

9103:CDX1
gene id: 9103:CDX1
uniprot id: G1N4V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9103:SST
gene id: 9103:SST
uniprot id: G1N6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

9103:VPS33A
gene id: 9103:VPS33A
uniprot id: A0A803YBI9
uniprot id: G1MZR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

9103:RHAG
gene id: 9103:RHAG
uniprot id: G3UT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9103:LOC104913618
gene id: 9103:LOC104913618
uniprot id: A0A803XV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9103:RSAD2
gene id: 9103:RSAD2
uniprot id: A0A803XVV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:SUCLG2
gene id: 9103:SUCLG2
uniprot id: G3UR69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

9103:NEUROD6
gene id: 9103:NEUROD6
uniprot id: G1NHS8
names: Subcellular Location Annotation
messages: Nucleus

9103:ST6GALNAC2
gene id: 9103:ST6GALNAC2
uniprot id: G1MYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9103:VANGL1
gene id: 9103:VANGL1
uniprot id: A0A803Y639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

9103:MEOX2
gene id: 9103:MEOX2
uniprot id: G1NCH1
names: Subcellular Location Annotation
messages: Nucleus

9103:INSIG2
gene id: 9103:INSIG2
uniprot id: G3UQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9103:SLC29A4
gene id: 9103:SLC29A4
uniprot id: A0A803XMH3
uniprot id: G1MXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9103:POMGNT2
gene id: 9103:POMGNT2
uniprot id: G1NS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:PTGER4
gene id: 9103:PTGER4
uniprot id: G1NR11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

9103:LOC100543487
gene id: 9103:LOC100543487
uniprot id: G3UQC5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9103:EREG
gene id: 9103:EREG
uniprot id: G1N5J0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:XRCC6
gene id: 9103:XRCC6
uniprot id: G1NHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

9103:RPS25
gene id: 9103:RPS25
uniprot id: G1MYC4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: Component of the small ribosomal subunit.

9103:SLC35A5
gene id: 9103:SLC35A5
uniprot id: G1NNF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9103:EIF3A
gene id: 9103:EIF3A
uniprot id: G1NFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

9103:UBE2E3
gene id: 9103:UBE2E3
uniprot id: A0A803XR59
uniprot id: G1NAG0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:SELENOK
gene id: 9103:SELENOK
uniprot id: L7Q485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

9103:PPTC7
gene id: 9103:PPTC7
uniprot id: G1N0F5
names: Similarity
messages: Belongs to the PP2C family.

9103:LOC100550910
gene id: 9103:LOC100550910
uniprot id: G3UQ02
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:PI4KA
gene id: 9103:PI4KA
uniprot id: G1MQF7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9103:TMPRSS2
gene id: 9103:TMPRSS2
uniprot id: G1NP04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:NSMCE4A
gene id: 9103:NSMCE4A
uniprot id: G1NG53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

9103:RGS4
gene id: 9103:RGS4
uniprot id: A0A803Y2G2
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

9103:LOC100548608
gene id: 9103:LOC100548608
uniprot id: G1NRD8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9103:SLC4A11
gene id: 9103:SLC4A11
uniprot id: A0A803XRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

9103:LOC100538725
gene id: 9103:LOC100538725
uniprot id: G1N332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

9103:UTP25
gene id: 9103:UTP25
uniprot id: A0A803YRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

9103:SLC6A7
gene id: 9103:SLC6A7
uniprot id: G1N4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9103:INPP5K
gene id: 9103:INPP5K
uniprot id: A0A803Y6E8
uniprot id: G1N0J3
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

9103:NDC80
gene id: 9103:NDC80
uniprot id: G1MYF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9103:LOC100549042
gene id: 9103:LOC100549042
uniprot id: G1NPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9103:HAPLN4
gene id: 9103:HAPLN4
uniprot id: G1MYU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:FABP7
gene id: 9103:FABP7
uniprot id: G1NKS8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:PKP1
gene id: 9103:PKP1
uniprot id: G1MT53
names: Similarity
messages: Belongs to the beta-catenin family.

9103:PRDM12
gene id: 9103:PRDM12
uniprot id: G1N1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

9103:CAV3
gene id: 9103:CAV3
uniprot id: G1NCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

9103:CHFR
gene id: 9103:CHFR
uniprot id: A0A803XUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

9103:LOC100548529
gene id: 9103:LOC100548529
uniprot id: G5E7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9103:SLC12A8
gene id: 9103:SLC12A8
uniprot id: G1NHS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9103:LOC100550421
gene id: 9103:LOC100550421
uniprot id: G1NED2
names: Similarity
messages: Belongs to the CRISP family.

9103:CYP3A80
gene id: 9103:CYP3A80
uniprot id: Q1PCR2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:GREM1
gene id: 9103:GREM1
uniprot id: G1NQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

9103:INO80C
gene id: 9103:INO80C
uniprot id: G1N4F7
names: Subcellular Location Annotation
messages: Nucleus

9103:RRAD
gene id: 9103:RRAD
uniprot id: G1N3C8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9103:COG2
gene id: 9103:COG2
uniprot id: G1NHM9
names: Similarity
messages: Belongs to the COG2 family.

9103:CCNDBP1
gene id: 9103:CCNDBP1
uniprot id: G1N0I5
names: Similarity
messages: Belongs to the CCNDBP1 family.

9103:HS3ST1
gene id: 9103:HS3ST1
uniprot id: G3UQ78
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9103:TMCC1
gene id: 9103:TMCC1
uniprot id: G1ND60
names: Similarity
messages: Belongs to the TEX28 family.

9103:PARD6B
gene id: 9103:PARD6B
uniprot id: G3USZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

9103:ZNF592
gene id: 9103:ZNF592
uniprot id: G1MQJ2
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9103:PTP4A2
gene id: 9103:PTP4A2
uniprot id: G1MZA9
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9103:TRPV3
gene id: 9103:TRPV3
uniprot id: A0A803Y4P2
uniprot id: G1N4L0
names: Subcellular Location Annotation
messages: Membrane

9103:SNX14
gene id: 9103:SNX14
uniprot id: A0A803XPY2
names: Similarity
messages: Belongs to the sorting nexin family.

9103:FZD9
gene id: 9103:FZD9
uniprot id: G1MQY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:PRKCE
gene id: 9103:PRKCE
uniprot id: G1NCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9103:DEGS1
gene id: 9103:DEGS1
uniprot id: G1N889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:GPLD1
gene id: 9103:GPLD1
uniprot id: G1MU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

9103:ATP1A1
gene id: 9103:ATP1A1
uniprot id: G1NNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

9103:HTR5A
gene id: 9103:HTR5A
uniprot id: A0A803YE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:PVALB
gene id: 9103:PVALB
uniprot id: G1NJ66
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

9103:UTP23
gene id: 9103:UTP23
uniprot id: A0A803XYP9
names: Subcellular Location Annotation
messages: nucleolus

9103:TAT
gene id: 9103:TAT
uniprot id: G1N9W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

9103:OPHN1
gene id: 9103:OPHN1
uniprot id: A0A803XMQ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

9103:LOC100539645
gene id: 9103:LOC100539645
uniprot id: A0A803XLX5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:LOC100540152
gene id: 9103:LOC100540152
uniprot id: A0A803XTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9103:SCNN1B
gene id: 9103:SCNN1B
uniprot id: G1N4H6
names: Subcellular Location Annotation
messages: Membrane

9103:LOC104910575
gene id: 9103:LOC104910575
uniprot id: A0A803Y8I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9103:ENTPD6
gene id: 9103:ENTPD6
uniprot id: G1N5M2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9103:LOC104909218
gene id: 9103:LOC104909218
uniprot id: A0A803XRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

9103:FXYD6
gene id: 9103:FXYD6
uniprot id: A0A803Y0C3
names: Similarity
messages: Belongs to the FXYD family.

9103:CLPTM1L
gene id: 9103:CLPTM1L
uniprot id: G1N5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

9103:BEST1
gene id: 9103:BEST1
uniprot id: G1NB42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Membrane

9103:LOC104910743
gene id: 9103:LOC104910743
uniprot id: G1MRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

9103:NPY2R
gene id: 9103:NPY2R
uniprot id: G1NS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:CSNK1G1
gene id: 9103:CSNK1G1
uniprot id: G1MRA7
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9103:ATIC
gene id: 9103:ATIC
uniprot id: G1MWQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

9103:VGLL4
gene id: 9103:VGLL4
uniprot id: G1N080
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

9103:MYO1G
gene id: 9103:MYO1G
uniprot id: G1MVR9
uniprot id: G3UR39
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9103:RALY
gene id: 9103:RALY
uniprot id: A0A803XWX7
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9103:RXFP1
gene id: 9103:RXFP1
uniprot id: G1MSR7
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:PRPSAP2
gene id: 9103:PRPSAP2
uniprot id: G1N0G0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9103:LOC100545821
gene id: 9103:LOC100545821
uniprot id: G1NLB2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9103:EXOC3
gene id: 9103:EXOC3
uniprot id: G1N6I0
names: Similarity
messages: Belongs to the SEC6 family.

9103:ALDH8A1
gene id: 9103:ALDH8A1
uniprot id: G1NK71
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9103:PTCD3
gene id: 9103:PTCD3
uniprot id: G1NKB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

9103:ARSA
gene id: 9103:ARSA
uniprot id: G1MU55
names: Similarity
messages: Belongs to the sulfatase family.

9103:TP63
gene id: 9103:TP63
uniprot id: A0A803YCS6
uniprot id: A0A803YHM5
uniprot id: G1MS14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

9103:HYOU1
gene id: 9103:HYOU1
uniprot id: G3UTS6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9103:EIF4A2
gene id: 9103:EIF4A2
uniprot id: G3UUH0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

9103:TAF2
gene id: 9103:TAF2
uniprot id: G3UUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

9103:RELL1
gene id: 9103:RELL1
uniprot id: G1NIE9
names: Similarity
messages: Belongs to the RELT family.

9103:USP37
gene id: 9103:USP37
uniprot id: G1NG28
names: Similarity
messages: Belongs to the peptidase C19 family.

9103:IRF5
gene id: 9103:IRF5
uniprot id: A0A803XRN1
names: Subcellular Location Annotation
messages: Nucleus

9103:CYP3A37
gene id: 9103:CYP3A37
uniprot id: Q1PCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9103:TMEM198
gene id: 9103:TMEM198
uniprot id: G1NFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

9103:LOC100541434
gene id: 9103:LOC100541434
uniprot id: G1NRI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:ASPN
gene id: 9103:ASPN
uniprot id: G1MZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

9103:HOXB3
gene id: 9103:HOXB3
uniprot id: G1MUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9103:LOC104909729
gene id: 9103:LOC104909729
uniprot id: A0A803XYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

9103:OTX2
gene id: 9103:OTX2
uniprot id: A0A803Y8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9103:LOC100541326
gene id: 9103:LOC100541326
uniprot id: G3UPG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC104914672
gene id: 9103:LOC104914672
uniprot id: G1MSU4
names: Similarity
messages: Belongs to the actin family.

9103:APOA5
gene id: 9103:APOA5
uniprot id: G1MVT5
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9103:LOC100549086
gene id: 9103:LOC100549086
uniprot id: G3UTL5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

9103:LOC100548731
gene id: 9103:LOC100548731
uniprot id: G1NKH2
names: Subcellular Location Annotation
messages: Membrane

9103:LOC109368447
gene id: 9103:LOC109368447
uniprot id: G1MX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9103:LOC100548490
gene id: 9103:LOC100548490
uniprot id: A0A803XZA4
names: Subcellular Location Annotation
messages: Membrane

9103:ATP12A
gene id: 9103:ATP12A
uniprot id: G1MSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

9103:DHDDS
gene id: 9103:DHDDS
uniprot id: A0A803YD73
names: Similarity
messages: Belongs to the UPP synthase family.

9103:HNF1A
gene id: 9103:HNF1A
uniprot id: G5E7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9103:SYT14
gene id: 9103:SYT14
uniprot id: A0A803XUU4
names: Similarity
messages: Belongs to the synaptotagmin family.

9103:ULK3
gene id: 9103:ULK3
uniprot id: G1MU05
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:C20H17orf80
gene id: 9103:C20H17orf80
uniprot id: A0A803YD61
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

9103:PRIMPOL
gene id: 9103:PRIMPOL
uniprot id: G1N3K7
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9103:LFNG
gene id: 9103:LFNG
uniprot id: G1MUY6
names: Subcellular Location Annotation
messages: Membrane

9103:NPY4R2
gene id: 9103:NPY4R2
uniprot id: G1NQX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:GDPD5
gene id: 9103:GDPD5
uniprot id: G3USK8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9103:NRDE2
gene id: 9103:NRDE2
uniprot id: A0A803YGT5
names: Similarity
messages: Belongs to the NRDE2 family.

9103:SLC35B3
gene id: 9103:SLC35B3
uniprot id: A0A803Y9Z5
uniprot id: G1MX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9103:SEC22C
gene id: 9103:SEC22C
uniprot id: G1MTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9103:EPCAM
gene id: 9103:EPCAM
uniprot id: G1N0W4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:NCOA2
gene id: 9103:NCOA2
uniprot id: A0A803YBV6
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

9103:MAP3K14
gene id: 9103:MAP3K14
uniprot id: G1NEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

9103:MRPL22
gene id: 9103:MRPL22
uniprot id: G1N1U9
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9103:VPS41
gene id: 9103:VPS41
uniprot id: G1NI09
uniprot id: G3UUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

9103:SCT
gene id: 9103:SCT
uniprot id: G1MXA8
names: Similarity
messages: Belongs to the glucagon family.

9103:NAP1L1
gene id: 9103:NAP1L1
uniprot id: G1NEH5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9103:RPLP1
gene id: 9103:RPLP1
uniprot id: G1NJV2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

9103:CDC42SE2
gene id: 9103:CDC42SE2
uniprot id: A0A803YDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

9103:TARDBP
gene id: 9103:TARDBP
uniprot id: G1MZJ1
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100548941
gene id: 9103:LOC100548941
uniprot id: A0A803XR11
names: Subcellular Location Annotation
messages: Membrane

9103:ALDOB
gene id: 9103:ALDOB
uniprot id: G1N4K3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9103:OGDHL
gene id: 9103:OGDHL
uniprot id: A0A803XLP4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9103:CTSH
gene id: 9103:CTSH
uniprot id: G1NDQ5
names: Similarity
messages: Belongs to the peptidase C1 family.

9103:EEF2K
gene id: 9103:EEF2K
uniprot id: A0A803XSC5
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

9103:YIPF1
gene id: 9103:YIPF1
uniprot id: G1NFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9103:ACLY
gene id: 9103:ACLY
uniprot id: A0A803YFY1
uniprot id: G1MW07
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

9103:SYNDIG1L
gene id: 9103:SYNDIG1L
uniprot id: G1NJ64
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9103:SLC16A12
gene id: 9103:SLC16A12
uniprot id: G1N8H8
names: Subcellular Location Annotation
messages: Membrane

9103:FAM3C
gene id: 9103:FAM3C
uniprot id: G1N943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9103:GPR12
gene id: 9103:GPR12
uniprot id: G1NRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:DPCD
gene id: 9103:DPCD
uniprot id: G1NCK4
names: Similarity
messages: Belongs to the DPCD family.

9103:PGM3
gene id: 9103:PGM3
uniprot id: A0A803YBZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

9103:LOC100547276
gene id: 9103:LOC100547276
uniprot id: A0A803XMI0
uniprot id: G1N1P8
names: Similarity
messages: Belongs to the SEC3 family.

9103:NUMB
gene id: 9103:NUMB
uniprot id: A0A803YGD4
uniprot id: A0A803YP34
uniprot id: G1NGK6
uniprot id: G1NGL4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

9103:CCNJL
gene id: 9103:CCNJL
uniprot id: G1MVB3
names: Similarity
messages: Belongs to the cyclin family.

9103:CAPN7
gene id: 9103:CAPN7
uniprot id: G1NFR6
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:AP4B1
gene id: 9103:AP4B1
uniprot id: G1N1P4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9103:AP4S1
gene id: 9103:AP4S1
uniprot id: A0A803Y1D9
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

9103:PSMB4
gene id: 9103:PSMB4
uniprot id: G1MR75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

9103:UGP2
gene id: 9103:UGP2
uniprot id: G1N004
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

9103:MOV10
gene id: 9103:MOV10
uniprot id: G1N067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

9103:MYADM
gene id: 9103:MYADM
uniprot id: G1NRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

9103:LOC100545463
gene id: 9103:LOC100545463
uniprot id: G3UR23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:CRLS1
gene id: 9103:CRLS1
uniprot id: G1N6X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

9103:TMEM43
gene id: 9103:TMEM43
uniprot id: A0A803YND6
uniprot id: G1N6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

9103:GRP
gene id: 9103:GRP
uniprot id: A0A803YA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

9103:OST4
gene id: 9103:OST4
uniprot id: A0A803Y7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:RARS2
gene id: 9103:RARS2
uniprot id: G1NLP0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9103:DDX6
gene id: 9103:DDX6
uniprot id: G1MYA1
names: Similarity
messages: Belongs to the DEAD box helicase family.

9103:PPARD
gene id: 9103:PPARD
uniprot id: G1N1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9103:VPS54
gene id: 9103:VPS54
uniprot id: G1MZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

9103:ENSA
gene id: 9103:ENSA
uniprot id: G1MPY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

9103:ADORA2A
gene id: 9103:ADORA2A
uniprot id: G1N7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9103:RPAP1
gene id: 9103:RPAP1
uniprot id: G1NFG8
names: Similarity
messages: Belongs to the RPAP1 family.

9103:CELF2
gene id: 9103:CELF2
uniprot id: A0A803Y057
uniprot id: A0A803Y5G9
uniprot id: A0A803YH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9103:SEPTIN10
gene id: 9103:SEPTIN10
uniprot id: A0A803XWV6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9103:LOC100538374
gene id: 9103:LOC100538374
uniprot id: G1MVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9103:NAE1
gene id: 9103:NAE1
uniprot id: G1N3N7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

9103:MTCP1
gene id: 9103:MTCP1
uniprot id: A0A803YND8
names: Similarity
messages: Belongs to the TCL1 family.

9103:GIP
gene id: 9103:GIP
uniprot id: G1N5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
messages: Secreted

9103:CUL5
gene id: 9103:CUL5
uniprot id: G1NQH7
names: Similarity
messages: Belongs to the cullin family.

9103:FGF23
gene id: 9103:FGF23
uniprot id: G1NM86
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9103:DHRS7
gene id: 9103:DHRS7
uniprot id: G1NLG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:DNAAF4
gene id: 9103:DNAAF4
uniprot id: G1N2N7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

9103:TYRP1
gene id: 9103:TYRP1
uniprot id: G1N1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

9103:SLC35F6
gene id: 9103:SLC35F6
uniprot id: G1NMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

9103:NEDD9
gene id: 9103:NEDD9
uniprot id: G1MWJ5
uniprot id: G3UNW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

9103:FAM118B
gene id: 9103:FAM118B
uniprot id: G1MPZ7
names: Similarity
messages: Belongs to the FAM118 family.

9103:LOC100550610
gene id: 9103:LOC100550610
uniprot id: G1NR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:TSSK6
gene id: 9103:TSSK6
uniprot id: G1NS75
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:HYAL1
gene id: 9103:HYAL1
uniprot id: G1MRN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9103:FGFR1OP2
gene id: 9103:FGFR1OP2
uniprot id: G1NLS7
names: Similarity
messages: Belongs to the SIKE family.

9103:LOC100539643
gene id: 9103:LOC100539643
uniprot id: G1NMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

9103:GSTA4
gene id: 9103:GSTA4
uniprot id: C8BLR6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9103:BLOC1S5
gene id: 9103:BLOC1S5
uniprot id: A0A803YSS8
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

9103:ECI1
gene id: 9103:ECI1
uniprot id: G1NA60
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9103:RPS7
gene id: 9103:RPS7
uniprot id: G1NMH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

9103:SARDH
gene id: 9103:SARDH
uniprot id: G1N4I4
names: Similarity
messages: Belongs to the GcvT family.

9103:OTULIN
gene id: 9103:OTULIN
uniprot id: G1N2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

9103:MEOX1
gene id: 9103:MEOX1
uniprot id: G3UTX0
names: Subcellular Location Annotation
messages: Nucleus

9103:AGPAT2
gene id: 9103:AGPAT2
uniprot id: G1N678
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

9103:FOXI1
gene id: 9103:FOXI1
uniprot id: G1MT33
names: Subcellular Location Annotation
messages: Nucleus

9103:NOS2
gene id: 9103:NOS2
uniprot id: G1N8R3
uniprot id: H6S058
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

9103:MASP1
gene id: 9103:MASP1
uniprot id: G1N6P6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:VILL
gene id: 9103:VILL
uniprot id: G1MWE6
names: Similarity
messages: Belongs to the villin/gelsolin family.

9103:DCLRE1A
gene id: 9103:DCLRE1A
uniprot id: G1NEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9103:LOC100544185
gene id: 9103:LOC100544185
uniprot id: G1MUM1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9103:SEC16A
gene id: 9103:SEC16A
uniprot id: A0A803XQG8
uniprot id: A0A803YDU8
uniprot id: G1N6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9103:TNFAIP2
gene id: 9103:TNFAIP2
uniprot id: G1NL04
names: Similarity
messages: Belongs to the SEC6 family.

9103:TNFRSF11B
gene id: 9103:TNFRSF11B
uniprot id: G1NIQ9
uniprot id: G3UUH8
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:GCG
gene id: 9103:GCG
uniprot id: Q3HLJ1
names: Similarity
messages: Belongs to the glucagon family.

9103:CEP55
gene id: 9103:CEP55
uniprot id: G1N9K8
names: Subcellular Location Annotation
messages: Cytoplasm

9103:SLC7A6
gene id: 9103:SLC7A6
uniprot id: G1MXI1
names: Subcellular Location Annotation
messages: Membrane

9103:CDX4
gene id: 9103:CDX4
uniprot id: A0A803YB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9103:MPP5
gene id: 9103:MPP5
uniprot id: G1NHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

9103:LOC100550526
gene id: 9103:LOC100550526
uniprot id: G1NLW9
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

9103:NUP155
gene id: 9103:NUP155
uniprot id: G1MWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

9103:MRPL53
gene id: 9103:MRPL53
uniprot id: A0A803YFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

9103:SPR
gene id: 9103:SPR
uniprot id: G1NKT4
names: Similarity
messages: Belongs to the sepiapterin reductase family.

9103:TACR2
gene id: 9103:TACR2
uniprot id: G1MZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:KDM3A
gene id: 9103:KDM3A
uniprot id: G3UQM5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

9103:GALK2
gene id: 9103:GALK2
uniprot id: G3UUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Nucleus

9103:PAQR8
gene id: 9103:PAQR8
uniprot id: G1NRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9103:ELF3
gene id: 9103:ELF3
uniprot id: A0A803XY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9103:KPNA4
gene id: 9103:KPNA4
uniprot id: G1NDL2
names: Similarity
messages: Belongs to the importin alpha family.

9103:POMGNT1
gene id: 9103:POMGNT1
uniprot id: G1NDR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

9103:EXTL1
gene id: 9103:EXTL1
uniprot id: G1MUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

9103:HDLBP
gene id: 9103:HDLBP
uniprot id: G1MXC2
names: Subcellular Location Annotation
messages: Cytoplasm

9103:TOR1B
gene id: 9103:TOR1B
uniprot id: G1N0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

9103:HMGCS2
gene id: 9103:HMGCS2
uniprot id: G1MZD6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

9103:GPAT3
gene id: 9103:GPAT3
uniprot id: A0A803Y3Y1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

9103:ENTPD1
gene id: 9103:ENTPD1
uniprot id: G1NAS8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9103:AZIN1
gene id: 9103:AZIN1
uniprot id: G1NIA3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9103:DIS3L2
gene id: 9103:DIS3L2
uniprot id: G1N815
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

9103:LOC100541867
gene id: 9103:LOC100541867
uniprot id: A0A803XNZ9
uniprot id: G1MYM8
names: Similarity
messages: Belongs to the hexokinase family.

9103:NKAIN1
gene id: 9103:NKAIN1
uniprot id: A0A803XPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9103:ATP6V1B2
gene id: 9103:ATP6V1B2
uniprot id: G1MSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

9103:TWSG1
gene id: 9103:TWSG1
uniprot id: G1NA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

9103:RAB3IP
gene id: 9103:RAB3IP
uniprot id: A0A803Y961
names: Similarity
messages: Belongs to the SEC2 family.

9103:ZBED1
gene id: 9103:ZBED1
uniprot id: G1NR66
names: Subcellular Location Annotation
messages: Nucleus

9103:SERINC1
gene id: 9103:SERINC1
uniprot id: G1NKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9103:LOC100548330
gene id: 9103:LOC100548330
uniprot id: A0A803YNF5
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9103:LZTFL1
gene id: 9103:LZTFL1
uniprot id: G1NGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

9103:SLC35A1
gene id: 9103:SLC35A1
uniprot id: G1NLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9103:TNNT2
gene id: 9103:TNNT2
uniprot id: Q90YN7
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9103:UBLCP1
gene id: 9103:UBLCP1
uniprot id: G1N014
names: Subcellular Location Annotation
messages: Nucleus

9103:AP1G1
gene id: 9103:AP1G1
uniprot id: G1N9R9
uniprot id: G5E7Y2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9103:TMEM263
gene id: 9103:TMEM263
uniprot id: G1NJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

9103:RBP4
gene id: 9103:RBP4
uniprot id: G3URC8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9103:IL4R
gene id: 9103:IL4R
uniprot id: G1N4R9
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

9103:SRPRA
gene id: 9103:SRPRA
uniprot id: G1MPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:ATXN1
gene id: 9103:ATXN1
uniprot id: A0A803XZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

9103:TMEM126A
gene id: 9103:TMEM126A
uniprot id: G1NQQ9
names: Subcellular Location Annotation
messages: Membrane

9103:NKAIN4
gene id: 9103:NKAIN4
uniprot id: A0A803YGL9
uniprot id: G1N397
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9103:LOC100544620
gene id: 9103:LOC100544620
uniprot id: G1MRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

9103:TGFA
gene id: 9103:TGFA
uniprot id: H9H1B9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:ERRFI1
gene id: 9103:ERRFI1
uniprot id: G1MQD7
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

9103:FSCN2
gene id: 9103:FSCN2
uniprot id: A0A803Y170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

9103:CIAPIN1
gene id: 9103:CIAPIN1
uniprot id: G1MW09
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

9103:NUDT12
gene id: 9103:NUDT12
uniprot id: A0A803YG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9103:HPSE
gene id: 9103:HPSE
uniprot id: G1N7R6
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9103:ZHX2
gene id: 9103:ZHX2
uniprot id: G1NRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

9103:AARS1
gene id: 9103:AARS1
uniprot id: G1MTB6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

9103:KLHL15
gene id: 9103:KLHL15
uniprot id: G1NP79
names: Subcellular Location Annotation
messages: Nucleus

9103:TTC19
gene id: 9103:TTC19
uniprot id: G1N3I3
names: Similarity
messages: Belongs to the TTC19 family.

9103:C2H6orf58
gene id: 9103:C2H6orf58
uniprot id: A0A803XPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

9103:LOC100540751
gene id: 9103:LOC100540751
uniprot id: A0A803Y629
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9103:PDE4B
gene id: 9103:PDE4B
uniprot id: G1NH48
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:ALDH1L2
gene id: 9103:ALDH1L2
uniprot id: G1NJU7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

9103:FAM234A
gene id: 9103:FAM234A
uniprot id: G1N9Q1
names: Similarity
messages: Belongs to the FAM234 family.

9103:SLC25A46
gene id: 9103:SLC25A46
uniprot id: G1N4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

9103:LOC100548654
gene id: 9103:LOC100548654
uniprot id: G1MXM6
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

9103:TRAF6
gene id: 9103:TRAF6
uniprot id: A0A803XVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

9103:IDH2
gene id: 9103:IDH2
uniprot id: H9H0Q1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

9103:LOC100543781
gene id: 9103:LOC100543781
uniprot id: G1NDR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9103:SYS1
gene id: 9103:SYS1
uniprot id: A0A803XU74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

9103:MOCOS
gene id: 9103:MOCOS
uniprot id: G1N4P3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

9103:SMIM15
gene id: 9103:SMIM15
uniprot id: G1NS00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

9103:ATP2A2
gene id: 9103:ATP2A2
uniprot id: G1MXU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9103:MAPK8
gene id: 9103:MAPK8
uniprot id: G1N7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9103:LMBR1
gene id: 9103:LMBR1
uniprot id: G1N0G8
names: Similarity
messages: Belongs to the LIMR family.

9103:CHRM4
gene id: 9103:CHRM4
uniprot id: G1NRP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

9103:MNAT1
gene id: 9103:MNAT1
uniprot id: G1NLE9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

9103:LOC100543476
gene id: 9103:LOC100543476
uniprot id: G1NR19
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:LOC100546874
gene id: 9103:LOC100546874
uniprot id: G1MSK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:SCMH1
gene id: 9103:SCMH1
uniprot id: A0A803Y777
uniprot id: G1MQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9103:TNFRSF10B
gene id: 9103:TNFRSF10B
uniprot id: O57408
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

9103:BEST4
gene id: 9103:BEST4
uniprot id: G1NCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

9103:CDC34
gene id: 9103:CDC34
uniprot id: G1MVS2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:PDE8B
gene id: 9103:PDE8B
uniprot id: G1MZV8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9103:LOC100546764
gene id: 9103:LOC100546764
uniprot id: G1N4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

9103:MRPL16
gene id: 9103:MRPL16
uniprot id: G1MWA3
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9103:HADH
gene id: 9103:HADH
uniprot id: G1N2B6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

9103:ANXA10
gene id: 9103:ANXA10
uniprot id: G1MU27
names: Similarity
messages: Belongs to the annexin family.

9103:GPHB5
gene id: 9103:GPHB5
uniprot id: G1NLC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9103:SYNGR3
gene id: 9103:SYNGR3
uniprot id: A0A803XVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

9103:SLC39A9
gene id: 9103:SLC39A9
uniprot id: G1NH09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

9103:ASIC1
gene id: 9103:ASIC1
uniprot id: H9H1S1
names: Subcellular Location Annotation
messages: Membrane

9103:MOGAT2
gene id: 9103:MOGAT2
uniprot id: A0A803XYS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:SLC17A5
gene id: 9103:SLC17A5
uniprot id: G1NM26
names: Subcellular Location Annotation
messages: Membrane

9103:IL2RG
gene id: 9103:IL2RG
uniprot id: G1N910
uniprot id: G3UTR4
names: Subcellular Location Annotation
messages: Membrane

9103:NLGN1
gene id: 9103:NLGN1
uniprot id: G3X8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9103:ATP4B
gene id: 9103:ATP4B
uniprot id: G1NPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9103:MYOZ2
gene id: 9103:MYOZ2
uniprot id: G1NE80
names: Similarity
messages: Belongs to the myozenin family.

9103:BMPR1B
gene id: 9103:BMPR1B
uniprot id: G1NF29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9103:VDAC3
gene id: 9103:VDAC3
uniprot id: A0A803XMJ1
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

9103:OSBPL6
gene id: 9103:OSBPL6
uniprot id: G1NB13
names: Similarity
messages: Belongs to the OSBP family.

9103:DUSP26
gene id: 9103:DUSP26
uniprot id: G1MS40
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

9103:SLC16A7
gene id: 9103:SLC16A7
uniprot id: G1NCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9103:AKR1A1
gene id: 9103:AKR1A1
uniprot id: G1NDE3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9103:TRAK2
gene id: 9103:TRAK2
uniprot id: G1N7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

9103:NCK2
gene id: 9103:NCK2
uniprot id: G1NPP1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

9103:DUSP10
gene id: 9103:DUSP10
uniprot id: G1N9X4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9103:ND4
gene id: 9103:ND4
uniprot id: A9XBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

9103:SLC37A1
gene id: 9103:SLC37A1
uniprot id: A0A803XRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9103:SLC13A2
gene id: 9103:SLC13A2
uniprot id: G1N241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9103:PHGDH
gene id: 9103:PHGDH
uniprot id: G1MZB5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

9103:HPD
gene id: 9103:HPD
uniprot id: G1MZ77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

9103:NKIRAS1
gene id: 9103:NKIRAS1
uniprot id: G1NEU2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

9103:TJP3
gene id: 9103:TJP3
uniprot id: G1MQN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

9103:LAPTM4A
gene id: 9103:LAPTM4A
uniprot id: G1NMN1
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9103:TPD52L2
gene id: 9103:TPD52L2
uniprot id: A0A803Y0R9
uniprot id: G1N4Q8
uniprot id: G3UUB1
names: Similarity
messages: Belongs to the TPD52 family.

9103:ERCC4
gene id: 9103:ERCC4
uniprot id: G1MQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

9103:PTPA
gene id: 9103:PTPA
uniprot id: G1N0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9103:CHRDL1
gene id: 9103:CHRDL1
uniprot id: G1N427
names: Subcellular Location Annotation
messages: Secreted

9103:LOC104912994
gene id: 9103:LOC104912994
uniprot id: A0A803Y555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: nuclear pore complex

9103:KIF9
gene id: 9103:KIF9
uniprot id: A0A803XQP9
uniprot id: G1MVA1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:PRCP
gene id: 9103:PRCP
uniprot id: G1NQQ2
names: Similarity
messages: Belongs to the peptidase S28 family.

9103:GKAP1
gene id: 9103:GKAP1
uniprot id: A0A803YL03
uniprot id: A0A803YMU4
names: Similarity
messages: Belongs to the GKAP1 family.

9103:PIGW
gene id: 9103:PIGW
uniprot id: G1NR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

9103:PSMG1
gene id: 9103:PSMG1
uniprot id: G1NNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with psmg2.

9103:TMEM132A
gene id: 9103:TMEM132A
uniprot id: G1MVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

9103:PRSS12
gene id: 9103:PRSS12
uniprot id: G1NEC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:TP53I11
gene id: 9103:TP53I11
uniprot id: A0A803XPR5
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100544306
gene id: 9103:LOC100544306
uniprot id: G3UQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

9103:SYT1
gene id: 9103:SYT1
uniprot id: G1NET9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

9103:LOC100545254
gene id: 9103:LOC100545254
uniprot id: A0A803YRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9103:STARD3
gene id: 9103:STARD3
uniprot id: H9H1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9103:MRPS14
gene id: 9103:MRPS14
uniprot id: G1MTD2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

9103:PSKH1
gene id: 9103:PSKH1
uniprot id: G1MUL2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:SLC16A3
gene id: 9103:SLC16A3
uniprot id: G1N1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9103:CDR2
gene id: 9103:CDR2
uniprot id: A0A803YSC5
names: Similarity
messages: Belongs to the CDR2 family.

9103:LOC100303695
gene id: 9103:LOC100303695
uniprot id: Q91090
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.
messages: Membrane
messages: The absence of paraoxonase activity in turkey and chicken blood and in turkey liver indicates that PON2, if expressed, does not hydrolyze paraoxon.
messages: The signal sequence is not cleaved.

9103:LOC100550265
gene id: 9103:LOC100550265
uniprot id: A0A803Y5Z5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

9103:PPP1R16B
gene id: 9103:PPP1R16B
uniprot id: G1MVT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:CLEC16A
gene id: 9103:CLEC16A
uniprot id: G1N8C6
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

9103:CDCA2
gene id: 9103:CDCA2
uniprot id: G1MQ64
names: Subcellular Location Annotation
messages: Nucleus

9103:DCP1A
gene id: 9103:DCP1A
uniprot id: G1N267
names: Similarity
messages: Belongs to the DCP1 family.

9103:OXSM
gene id: 9103:OXSM
uniprot id: G1NF32
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

9103:GPX4
gene id: 9103:GPX4
uniprot id: D2J268
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9103:HAUS1
gene id: 9103:HAUS1
uniprot id: G1MS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

9103:UCN3
gene id: 9103:UCN3
uniprot id: G1MX10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9103:DDX3X
gene id: 9103:DDX3X
uniprot id: G1NP43
names: Similarity
messages: Belongs to the DEAD box helicase family.

9103:PDGFRB
gene id: 9103:PDGFRB
uniprot id: G1N4V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9103:SGSM3
gene id: 9103:SGSM3
uniprot id: G1NI77
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

9103:GUCY1B1
gene id: 9103:GUCY1B1
uniprot id: A0A803Y2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

9103:RPL37A
gene id: 9103:RPL37A
uniprot id: G1NGI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9103:ATP6V1C2
gene id: 9103:ATP6V1C2
uniprot id: G1NMK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9103:LOC100539605
gene id: 9103:LOC100539605
uniprot id: A0A803Y3W9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

9103:AQP1
gene id: 9103:AQP1
uniprot id: G1MSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

9103:FGFBP1
gene id: 9103:FGFBP1
uniprot id: G1NJ28
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

9103:RAB4A
gene id: 9103:RAB4A
uniprot id: A0A803YGP3
uniprot id: G1NHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

9103:POLR3H
gene id: 9103:POLR3H
uniprot id: G1NHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

9103:PARL
gene id: 9103:PARL
uniprot id: G1MQB7
names: Subcellular Location Annotation
messages: Membrane

9103:LOC100551099
gene id: 9103:LOC100551099
uniprot id: G1MWA9
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

9103:SLC41A2
gene id: 9103:SLC41A2
uniprot id: G1NJV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9103:NPY1R
gene id: 9103:NPY1R
uniprot id: G1MTE8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:KIF11
gene id: 9103:KIF11
uniprot id: A0A803YS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

9103:GPR161
gene id: 9103:GPR161
uniprot id: G1NNG3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9103:CRYAB
gene id: 9103:CRYAB
uniprot id: G1MZP6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9103:KRAS
gene id: 9103:KRAS
uniprot id: P79800
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Cell membrane
messages: Cytoplasm
messages: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs).

9103:ANAPC13
gene id: 9103:ANAPC13
uniprot id: A0A803YMF5
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

9103:CDK1
gene id: 9103:CDK1
uniprot id: G1MVE7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9103:TYW3
gene id: 9103:TYW3
uniprot id: G1NHT7
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

9103:RIDA
gene id: 9103:RIDA
uniprot id: G1NHU5
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

9103:CAPN6
gene id: 9103:CAPN6
uniprot id: G1N408
names: Similarity
messages: Belongs to the peptidase C2 family.

9103:LOC100545119
gene id: 9103:LOC100545119
uniprot id: A0A803Y397
uniprot id: G1MUG2
names: Subcellular Location Annotation
messages: Membrane

9103:RAD54L2
gene id: 9103:RAD54L2
uniprot id: A0A803Y4T1
uniprot id: G1MVA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9103:KIF4A
gene id: 9103:KIF4A
uniprot id: G1MS31
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9103:RAB9A
gene id: 9103:RAB9A
uniprot id: A0A803YM94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

9103:POT1
gene id: 9103:POT1
uniprot id: G5E7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

9103:CD79B
gene id: 9103:CD79B
uniprot id: G3UV51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9103:PRKCQ
gene id: 9103:PRKCQ
uniprot id: G1MY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9103:SSH1
gene id: 9103:SSH1
uniprot id: G1N2H9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9103:OGG1
gene id: 9103:OGG1
uniprot id: G1N8C7
names: Similarity
messages: Belongs to the type-1 OGG1 family.

9103:BRINP1
gene id: 9103:BRINP1
uniprot id: G1MW42
names: Similarity
messages: Belongs to the BRINP family.

9103:HINT1
gene id: 9103:HINT1
uniprot id: G1N4D3
names: Similarity
messages: Belongs to the HINT family.

9103:CRHR2
gene id: 9103:CRHR2
uniprot id: A0A803XPP2
uniprot id: G1MVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

9103:LOC100544372
gene id: 9103:LOC100544372
uniprot id: H9H0S9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:BUD31
gene id: 9103:BUD31
uniprot id: G1MYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

9103:IWS1
gene id: 9103:IWS1
uniprot id: G1MRV2
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100546358
gene id: 9103:LOC100546358
uniprot id: A0A803YGR1
uniprot id: G1N1C6
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

9103:B4GALNT4
gene id: 9103:B4GALNT4
uniprot id: A0A803XMU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

9103:LOC100550530
gene id: 9103:LOC100550530
uniprot id: G1NQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9103:COL4A1
gene id: 9103:COL4A1
uniprot id: A0A803YH11
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9103:IMPA1
gene id: 9103:IMPA1
uniprot id: G1NGK8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9103:SMAD3
gene id: 9103:SMAD3
uniprot id: G1NC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9103:LOC100538523
gene id: 9103:LOC100538523
uniprot id: G1MSG1
names: Subcellular Location Annotation
messages: Membrane

9103:PAIP2
gene id: 9103:PAIP2
uniprot id: G1MRE8
names: Similarity
messages: Belongs to the PAIP2 family.

9103:EIF5B
gene id: 9103:EIF5B
uniprot id: G1NPL0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

9103:PUS1
gene id: 9103:PUS1
uniprot id: G1MSZ1
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

9103:GATA-4
gene id: 9103:GATA-4
uniprot id: G1NN28
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100551072
gene id: 9103:LOC100551072
uniprot id: G1N9G9
names: Similarity
messages: Belongs to the globin family.

9103:PPDPFL
gene id: 9103:PPDPFL
uniprot id: A0A803YKW9
names: Similarity
messages: Belongs to the PPDPF family.

9103:LOC100549255
gene id: 9103:LOC100549255
uniprot id: A0A803XLJ4
uniprot id: A0A803XR41
uniprot id: A0A803Y1R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:SPDL1
gene id: 9103:SPDL1
uniprot id: G1MTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

9103:CALHM1
gene id: 9103:CALHM1
uniprot id: G1NDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9103:LOC100545667
gene id: 9103:LOC100545667
uniprot id: A0A803YF57
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

9103:CDC123
gene id: 9103:CDC123
uniprot id: G1MZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

9103:USP16
gene id: 9103:USP16
uniprot id: G1NNU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Homotetramer.
messages: Nucleus
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

9103:SLC5A8
gene id: 9103:SLC5A8
uniprot id: G1NGQ1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9103:AQP11
gene id: 9103:AQP11
uniprot id: G1NQT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

9103:LOC100541467
gene id: 9103:LOC100541467
uniprot id: G1N1V2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9103:CLGN
gene id: 9103:CLGN
uniprot id: G1MVE5
names: Similarity
messages: Belongs to the calreticulin family.

9103:TRNT1
gene id: 9103:TRNT1
uniprot id: G1NC81
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

9103:TAFA1
gene id: 9103:TAFA1
uniprot id: A0A803Y8W6
uniprot id: G1NAQ2
names: Similarity
messages: Belongs to the TAFA family.

9103:CAPZA2
gene id: 9103:CAPZA2
uniprot id: G1N9Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9103:FAT1
gene id: 9103:FAT1
uniprot id: A0A803XKS9
uniprot id: A0A803Y7D5
uniprot id: G1NG27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:CNTN1
gene id: 9103:CNTN1
uniprot id: G3URJ3
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

9103:PLAT
gene id: 9103:PLAT
uniprot id: G1MVL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:PHF10
gene id: 9103:PHF10
uniprot id: G1NHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

9103:GINS2
gene id: 9103:GINS2
uniprot id: G1N6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Nucleus

9103:ELAVL1
gene id: 9103:ELAVL1
uniprot id: G1MQP8
uniprot id: G3UQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

9103:TBPL1
gene id: 9103:TBPL1
uniprot id: G3UQK3
names: Similarity
messages: Belongs to the TBP family.

9103:CENPM
gene id: 9103:CENPM
uniprot id: G1NHN7
names: Subcellular Location Annotation
messages: Nucleus

9103:UXS1
gene id: 9103:UXS1
uniprot id: G1NPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

9103:SLC5A1
gene id: 9103:SLC5A1
uniprot id: G1N7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9103:NKX6-3
gene id: 9103:NKX6-3
uniprot id: G1MWJ7
names: Subcellular Location Annotation
messages: Nucleus

9103:IP6K3
gene id: 9103:IP6K3
uniprot id: H9H1P0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9103:LOC100538652
gene id: 9103:LOC100538652
uniprot id: A0A803Y8J2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

9103:DNAJC24
gene id: 9103:DNAJC24
uniprot id: G1MS41
names: Similarity
messages: Belongs to the DPH4 family.

9103:PPP1R13B
gene id: 9103:PPP1R13B
uniprot id: G1NL33
names: Subcellular Location Annotation
messages: Nucleus

9103:PDCD10
gene id: 9103:PDCD10
uniprot id: G1NDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9103:UBE2I
gene id: 9103:UBE2I
uniprot id: G1N4Y6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9103:LOC100545341
gene id: 9103:LOC100545341
uniprot id: G3UUQ6
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

9103:LOC100542413
gene id: 9103:LOC100542413
uniprot id: G1NRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9103:RSRP1
gene id: 9103:RSRP1
uniprot id: G1MT28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSRP family.
messages: Nucleus
messages: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.

9103:CPM
gene id: 9103:CPM
uniprot id: G1NDL5
names: Similarity
messages: Belongs to the peptidase M14 family.

9103:LOC100547473
gene id: 9103:LOC100547473
uniprot id: G1NK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC100543119
gene id: 9103:LOC100543119
uniprot id: G1MXZ8
names: Subcellular Location Annotation
messages: Membrane

9103:FAM114A2
gene id: 9103:FAM114A2
uniprot id: G1N2C4
names: Similarity
messages: Belongs to the FAM114 family.

9103:DUT
gene id: 9103:DUT
uniprot id: G1N547
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

9103:B4GALT6
gene id: 9103:B4GALT6
uniprot id: A0A803YSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9103:LOC100550520
gene id: 9103:LOC100550520
uniprot id: H9H1I8
names: Similarity
messages: Belongs to the AAA ATPase family.

9103:GBF1
gene id: 9103:GBF1
uniprot id: G1N5L0
names: Subcellular Location Annotation
messages: Golgi apparatus

9103:PDCD4
gene id: 9103:PDCD4
uniprot id: G1NEE4
names: Similarity
messages: Belongs to the PDCD4 family.

9103:ORMDL3
gene id: 9103:ORMDL3
uniprot id: H9H0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

9103:SLC7A3
gene id: 9103:SLC7A3
uniprot id: G1MTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9103:EPN2
gene id: 9103:EPN2
uniprot id: A0A803XVF7
names: Similarity
messages: Belongs to the epsin family.

9103:POMK
gene id: 9103:POMK
uniprot id: G1MZ90
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

9103:DCK
gene id: 9103:DCK
uniprot id: A0A803XPU9
names: Similarity
messages: Belongs to the DCK/DGK family.

9103:STK3
gene id: 9103:STK3
uniprot id: G1NHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

9103:FN3K
gene id: 9103:FN3K
uniprot id: G1MX32
names: Similarity
messages: Belongs to the fructosamine kinase family.

9103:LOC100546611
gene id: 9103:LOC100546611
uniprot id: G1MQ76
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9103:LOC100545586
gene id: 9103:LOC100545586
uniprot id: G1N0Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100548019
gene id: 9103:LOC100548019
uniprot id: G1NNC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9103:ATP8
gene id: 9103:ATP8
uniprot id: A9XBE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Membrane
messages: Mitochondrion membrane

9103:TDP1
gene id: 9103:TDP1
uniprot id: A0A803YQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

9103:LOC100540871
gene id: 9103:LOC100540871
uniprot id: G1MVJ4
names: Similarity
messages: Belongs to the intermediate filament family.

9103:ESRRG
gene id: 9103:ESRRG
uniprot id: A0A803Y336
uniprot id: A0A803YQB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9103:SCD5
gene id: 9103:SCD5
uniprot id: G1N7I0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9103:ATF7IP
gene id: 9103:ATF7IP
uniprot id: G1NHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

9103:FAM122B
gene id: 9103:FAM122B
uniprot id: G1MW93
names: Similarity
messages: Belongs to the FAM122 family.

9103:FOXO3
gene id: 9103:FOXO3
uniprot id: G1NL82
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100543595
gene id: 9103:LOC100543595
uniprot id: A0A803XME0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9103:PLA2G15
gene id: 9103:PLA2G15
uniprot id: A0A803XMQ0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9103:TACR1
gene id: 9103:TACR1
uniprot id: A0A803YEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9103:TNMD
gene id: 9103:TNMD
uniprot id: G1MYQ6
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9103:WARS2
gene id: 9103:WARS2
uniprot id: A0A803XM46
uniprot id: G1NN51
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9103:CCN6
gene id: 9103:CCN6
uniprot id: G1NL19
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9103:HGD
gene id: 9103:HGD
uniprot id: G1NN95
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

9103:HIKESHI
gene id: 9103:HIKESHI
uniprot id: G1NQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

9103:ELL2
gene id: 9103:ELL2
uniprot id: G1MYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

9103:FAM102A
gene id: 9103:FAM102A
uniprot id: G1MWZ5
names: Similarity
messages: Belongs to the EEIG family.

9103:SLC26A3
gene id: 9103:SLC26A3
uniprot id: G1NC25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
messages: Membrane

9103:SMARCAL1
gene id: 9103:SMARCAL1
uniprot id: G1NGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

9103:SEC61G
gene id: 9103:SEC61G
uniprot id: G1NIC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9103:LOC100546173
gene id: 9103:LOC100546173
uniprot id: G1NNA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9103:LDLRAD4
gene id: 9103:LDLRAD4
uniprot id: A0A803YQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

9103:PAPPA
gene id: 9103:PAPPA
uniprot id: G1MVW6
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:NPFFR1
gene id: 9103:NPFFR1
uniprot id: G1N157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9103:SLC2A2
gene id: 9103:SLC2A2
uniprot id: G1NCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

9103:LOC100543381
gene id: 9103:LOC100543381
uniprot id: A0A803YDZ0
uniprot id: A0A803YQI8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

9103:B3GNT5
gene id: 9103:B3GNT5
uniprot id: G1NS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:MMP11
gene id: 9103:MMP11
uniprot id: G1N605
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

9103:KCNJ1
gene id: 9103:KCNJ1
uniprot id: G1NRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9103:MYLK
gene id: 9103:MYLK
uniprot id: G1U9Q7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9103:SRC
gene id: 9103:SRC
uniprot id: G1MWN3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

9103:PRPF4
gene id: 9103:PRPF4
uniprot id: G1MSK8
names: Subcellular Location Annotation
messages: Nucleus speckle

9103:SHCBP1
gene id: 9103:SHCBP1
uniprot id: G1N165
names: Subcellular Location Annotation
messages: spindle

9103:PSME3IP1
gene id: 9103:PSME3IP1
uniprot id: G1MV56
names: Subcellular Location Annotation
messages: Nucleus

9103:APOB
gene id: 9103:APOB
uniprot id: G1NMN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:NECAP2
gene id: 9103:NECAP2
uniprot id: G1N0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9103:SS18L1
gene id: 9103:SS18L1
uniprot id: G1N1D5
names: Similarity
messages: Belongs to the SS18 family.

9103:ARCN1
gene id: 9103:ARCN1
uniprot id: G1MXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9103:FAM149B1
gene id: 9103:FAM149B1
uniprot id: G1MRF1
names: Similarity
messages: Belongs to the FAM149 family.

9103:BCL9L
gene id: 9103:BCL9L
uniprot id: G1MYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9103:OGN
gene id: 9103:OGN
uniprot id: G1MZ49
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

9103:CD34
gene id: 9103:CD34
uniprot id: G1MYF5
names: Subcellular Location Annotation
messages: Membrane

9103:DUOXA2
gene id: 9103:DUOXA2
uniprot id: G1MQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9103:EIF4E2
gene id: 9103:EIF4E2
uniprot id: A0A803YFV5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9103:TRRAP
gene id: 9103:TRRAP
uniprot id: A0A803YM31
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

9103:PTGES2
gene id: 9103:PTGES2
uniprot id: A0A803YS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

9103:LEPROT
gene id: 9103:LEPROT
uniprot id: Q5PSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).
messages: Widely expressed, including in liver, duodenum, kidney, pancreas, lung, spleen and brain.

9103:PELI1
gene id: 9103:PELI1
uniprot id: A0A803YEP7
names: Similarity
messages: Belongs to the pellino family.

9103:SLC35F4
gene id: 9103:SLC35F4
uniprot id: A0A803YEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9103:NSMCE2
gene id: 9103:NSMCE2
uniprot id: G1NJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

9103:RBBP7
gene id: 9103:RBBP7
uniprot id: G1NPB0
names: Subcellular Location Annotation
messages: Nucleus

9103:ASPH
gene id: 9103:ASPH
uniprot id: A0A803Y3B3
uniprot id: A0A803Y653
uniprot id: A0A803Y6V7
uniprot id: A0A803YF48
uniprot id: A0A803YRZ2
uniprot id: G1NF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

9103:AK8
gene id: 9103:AK8
uniprot id: G1N2Z2
names: Similarity
messages: Belongs to the adenylate kinase family.

9103:SLC26A5
gene id: 9103:SLC26A5
uniprot id: A0A803YKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

9103:RBP7
gene id: 9103:RBP7
uniprot id: A0A803XZB3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:GATA2
gene id: 9103:GATA2
uniprot id: G1N5I0
names: Subcellular Location Annotation
messages: Nucleus

9103:LOC100550679
gene id: 9103:LOC100550679
uniprot id: G1NLX1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9103:CPSF4
gene id: 9103:CPSF4
uniprot id: G1MYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

9103:ABCC10
gene id: 9103:ABCC10
uniprot id: G1NEX8
names: Subcellular Location Annotation
messages: Membrane

9103:C17H12orf65
gene id: 9103:C17H12orf65
uniprot id: G1MWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9103:ATP6AP1L
gene id: 9103:ATP6AP1L
uniprot id: G1MXT4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

9103:LAMP1
gene id: 9103:LAMP1
uniprot id: G1NPR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9103:SPO11
gene id: 9103:SPO11
uniprot id: G1NA79
names: Similarity
messages: Belongs to the TOP6A family.

9103:RBFOX2
gene id: 9103:RBFOX2
uniprot id: G1NJB4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

9103:NELL1
gene id: 9103:NELL1
uniprot id: A0A803YBE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:LOC100538588
gene id: 9103:LOC100538588
uniprot id: G1NE87
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:ARAP2
gene id: 9103:ARAP2
uniprot id: A0A803Y6M9
uniprot id: G1NIF5
uniprot id: G3URL4
names: Subcellular Location Annotation
messages: Cytoplasm

9103:POLR2H
gene id: 9103:POLR2H
uniprot id: A0A803XTV4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

9103:APLP2
gene id: 9103:APLP2
uniprot id: G1MQW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9103:DAG1
gene id: 9103:DAG1
uniprot id: G1MW21
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

9103:SLC25A25
gene id: 9103:SLC25A25
uniprot id: G1MWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9103:WASHC5
gene id: 9103:WASHC5
uniprot id: G1NJ93
names: Similarity
messages: Belongs to the strumpellin family.

9103:CHEK1
gene id: 9103:CHEK1
uniprot id: H9H052
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

9103:LCA5
gene id: 9103:LCA5
uniprot id: A0A803XV60
names: Similarity
messages: Belongs to the LCA5 family.

9103:LOC104916371
gene id: 9103:LOC104916371
uniprot id: A0A803XMX3
names: Similarity
messages: Belongs to the CYFIP family.

9103:ALB
gene id: 9103:ALB
uniprot id: G1NCR2
names: Subcellular Location Annotation
messages: Secreted

9103:LOC100548322
gene id: 9103:LOC100548322
uniprot id: A0A803XY98
names: Similarity
messages: Belongs to the cytochrome P450 family.

9103:PDP2
gene id: 9103:PDP2
uniprot id: G1NRD6
names: Similarity
messages: Belongs to the PP2C family.

9103:COG7
gene id: 9103:COG7
uniprot id: G1N4F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

9103:GABARAPL1
gene id: 9103:GABARAPL1
uniprot id: G1NN47
names: Similarity
messages: Belongs to the ATG8 family.

9103:SETD2
gene id: 9103:SETD2
uniprot id: G1MV76
names: Subcellular Location Annotation
messages: Nucleus

9103:MSH2
gene id: 9103:MSH2
uniprot id: G1N0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

9103:MMUT
gene id: 9103:MMUT
uniprot id: G1NN78
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

9103:CRABP2
gene id: 9103:CRABP2
uniprot id: H9H0C7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

9103:NELL2
gene id: 9103:NELL2
uniprot id: G1NBC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:DIPK2B
gene id: 9103:DIPK2B
uniprot id: G1NP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

9103:VBP1
gene id: 9103:VBP1
uniprot id: G1N508
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

9103:TMEM30A
gene id: 9103:TMEM30A
uniprot id: G1NM03
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

9103:KATNB1
gene id: 9103:KATNB1
uniprot id: G1MWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9103:PDLIM3
gene id: 9103:PDLIM3
uniprot id: G3UQT4
names: Subcellular Location Annotation
messages: Z line

9103:C5
gene id: 9103:C5
uniprot id: G1MWZ9
names: Subcellular Location Annotation
messages: Secreted

9103:NRG3
gene id: 9103:NRG3
uniprot id: G1MQD5
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9103:NOS1
gene id: 9103:NOS1
uniprot id: G1NC69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

9103:ACADS
gene id: 9103:ACADS
uniprot id: A0A803YJE6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9103:CHL1
gene id: 9103:CHL1
uniprot id: A0A803XYV6
uniprot id: A0A803YQL7
uniprot id: G1NBU8
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

9103:LOC100539493
gene id: 9103:LOC100539493
uniprot id: A0A803XR55
uniprot id: G1NEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Microsome membrane

9103:EEF1AKMT1
gene id: 9103:EEF1AKMT1
uniprot id: G1NQF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

9103:SIAH1
gene id: 9103:SIAH1
uniprot id: G1NRC3
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9103:PLCG2
gene id: 9103:PLCG2
uniprot id: G1N518
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9103:DOCK11
gene id: 9103:DOCK11
uniprot id: A0A803XVX7
names: Similarity
messages: Belongs to the DOCK family.

9103:KCNH5
gene id: 9103:KCNH5
uniprot id: G1NLD0
names: Subcellular Location Annotation
messages: Membrane

9103:PRKAA2
gene id: 9103:PRKAA2
uniprot id: A1E4B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm
messages: Nucleus

9103:ARL6IP5
gene id: 9103:ARL6IP5
uniprot id: A0A803XP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

9103:AQP3
gene id: 9103:AQP3
uniprot id: A0A803YCX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9103:LOC100545121
gene id: 9103:LOC100545121
uniprot id: G1NQZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

9103:SMC4
gene id: 9103:SMC4
uniprot id: G1NDP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

9103:CHAT
gene id: 9103:CHAT
uniprot id: G1MTK0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9103:LOC100541395
gene id: 9103:LOC100541395
uniprot id: G1NQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus