446471:XCEL RS10245
gene id: 446471:XCEL_RS10245
uniprot id: D1BTS8
names: Similarity
messages: Belongs to the glutamine synthetase family.

446471:XCEL RS05200
gene id: 446471:XCEL_RS05200
uniprot id: D1BYZ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446471:XCEL RS06110
gene id: 446471:XCEL_RS06110
uniprot id: D1C058
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

446471:XCEL RS14660
gene id: 446471:XCEL_RS14660
uniprot id: D1BZ30
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS06210
gene id: 446471:XCEL_RS06210
uniprot id: D1C078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

446471:XCEL RS12510
gene id: 446471:XCEL_RS12510
uniprot id: D1BWF4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS08385
gene id: 446471:XCEL_RS08385
uniprot id: D1BSK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446471:XCEL RS06665
gene id: 446471:XCEL_RS06665
uniprot id: D1BRA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

446471:XCEL RS19015
gene id: 446471:XCEL_RS19015
uniprot id: D1C0C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS02425
gene id: 446471:XCEL_RS02425
uniprot id: D1BW18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446471:XCEL RS06320
gene id: 446471:XCEL_RS06320
uniprot id: D1C0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

446471:XCEL RS00935
gene id: 446471:XCEL_RS00935
uniprot id: D1BUI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

446471:XCEL RS06755
gene id: 446471:XCEL_RS06755
uniprot id: D1BRB8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

446471:XCEL RS14280
gene id: 446471:XCEL_RS14280
uniprot id: D1BYH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS05460
gene id: 446471:XCEL_RS05460
uniprot id: D1BZG6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

446471:XCEL RS05520
gene id: 446471:XCEL_RS05520
uniprot id: D1BZH8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

446471:XCEL RS03115
gene id: 446471:XCEL_RS03115
uniprot id: D1BWS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446471:XCEL RS17245
gene id: 446471:XCEL_RS17245
uniprot id: D1C0X5
names: Similarity
messages: Belongs to the peptidase C40 family.

446471:XCEL RS08380
gene id: 446471:XCEL_RS08380
uniprot id: D1BSK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

446471:XCEL RS13940
gene id: 446471:XCEL_RS13940
uniprot id: D1BXZ0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446471:XCEL RS14250
gene id: 446471:XCEL_RS14250
uniprot id: D1BYH0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

446471:XCEL RS15210
gene id: 446471:XCEL_RS15210
uniprot id: D1BZQ7
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

446471:XCEL RS13270
gene id: 446471:XCEL_RS13270
uniprot id: D1BX81
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

446471:XCEL RS01300
gene id: 446471:XCEL_RS01300
uniprot id: D1BUQ4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446471:XCEL RS13675
gene id: 446471:XCEL_RS13675
uniprot id: D1BXT7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05515
gene id: 446471:XCEL_RS05515
uniprot id: D1BZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

446471:XCEL RS12150
gene id: 446471:XCEL_RS12150
uniprot id: D1BVV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446471:XCEL RS00260
gene id: 446471:XCEL_RS00260
uniprot id: D1BTE8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15390
gene id: 446471:XCEL_RS15390
uniprot id: D1BZU1
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS13665
gene id: 446471:XCEL_RS13665
uniprot id: D1BXT5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS08680
gene id: 446471:XCEL_RS08680
uniprot id: D1BSR0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

446471:XCEL RS12350
gene id: 446471:XCEL_RS12350
uniprot id: D1BWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

446471:XCEL RS05900
gene id: 446471:XCEL_RS05900
uniprot id: D1C017
names: Similarity
messages: Belongs to the UPF0102 family.

446471:XCEL RS04930
gene id: 446471:XCEL_RS04930
uniprot id: D1BYU3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

446471:XCEL RS01395
gene id: 446471:XCEL_RS01395
uniprot id: D1BUS3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS08645
gene id: 446471:XCEL_RS08645
uniprot id: D1BSQ3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

446471:XCEL RS03160
gene id: 446471:XCEL_RS03160
uniprot id: D1BWT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

446471:XCEL RS02255
gene id: 446471:XCEL_RS02255
uniprot id: D1BVY4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS13280
gene id: 446471:XCEL_RS13280
uniprot id: D1BX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446471:XCEL RS08565
gene id: 446471:XCEL_RS08565
uniprot id: D1BSN7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

446471:XCEL RS03695
gene id: 446471:XCEL_RS03695
uniprot id: D1BXG6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

446471:XCEL RS08260
gene id: 446471:XCEL_RS08260
uniprot id: D1BSH6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

446471:XCEL RS12580
gene id: 446471:XCEL_RS12580
uniprot id: D1BWG8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15660
gene id: 446471:XCEL_RS15660
uniprot id: D1BZZ1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS00405
gene id: 446471:XCEL_RS00405
uniprot id: D1BTV5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

446471:XCEL RS15845
gene id: 446471:XCEL_RS15845
uniprot id: D1C0F3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

446471:XCEL RS12365
gene id: 446471:XCEL_RS12365
uniprot id: D1BWC6
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01620
gene id: 446471:XCEL_RS01620
uniprot id: D1BV88
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

446471:XCEL RS14900
gene id: 446471:XCEL_RS14900
uniprot id: D1BZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS03050
gene id: 446471:XCEL_RS03050
uniprot id: D1BWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS08650
gene id: 446471:XCEL_RS08650
uniprot id: D1BSQ4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

446471:XCEL RS01010
gene id: 446471:XCEL_RS01010
uniprot id: D1BUJ7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS03540
gene id: 446471:XCEL_RS03540
uniprot id: D1BXD4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

446471:XCEL RS08395
gene id: 446471:XCEL_RS08395
uniprot id: D1BSK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS16825
gene id: 446471:XCEL_RS16825
uniprot id: D1BRT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

446471:XCEL RS07185
gene id: 446471:XCEL_RS07185
uniprot id: D1BRX1
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS07090
gene id: 446471:XCEL_RS07090
uniprot id: D1BRI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

446471:XCEL RS15855
gene id: 446471:XCEL_RS15855
uniprot id: D1C0F5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS01375
gene id: 446471:XCEL_RS01375
uniprot id: D1BUR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

446471:XCEL RS00270
gene id: 446471:XCEL_RS00270
uniprot id: D1BTF0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

446471:XCEL RS08535
gene id: 446471:XCEL_RS08535
uniprot id: D1BSN1
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00565
gene id: 446471:XCEL_RS00565
uniprot id: D1BTY8
names: Similarity
messages: Belongs to the AHA1 family.

446471:XCEL RS16020
gene id: 446471:XCEL_RS16020
uniprot id: D1C0I7
names: Similarity
messages: Belongs to the pirin family.

446471:XCEL RS13260
gene id: 446471:XCEL_RS13260
uniprot id: D1BX79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

446471:XCEL RS05045
gene id: 446471:XCEL_RS05045
uniprot id: D1BYW7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03570
gene id: 446471:XCEL_RS03570
uniprot id: D1BXE0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446471:XCEL RS12560
gene id: 446471:XCEL_RS12560
uniprot id: D1BWG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446471:XCEL RS03750
gene id: 446471:XCEL_RS03750
uniprot id: D1BXH7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

446471:XCEL RS11540
gene id: 446471:XCEL_RS11540
uniprot id: D1BVJ4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS07230
gene id: 446471:XCEL_RS07230
uniprot id: D1BRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

446471:XCEL RS14030
gene id: 446471:XCEL_RS14030
uniprot id: D1BYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS05930
gene id: 446471:XCEL_RS05930
uniprot id: D1C023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

446471:XCEL RS03560
gene id: 446471:XCEL_RS03560
uniprot id: D1BXD8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS10830
gene id: 446471:XCEL_RS10830
uniprot id: D1BUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS12655
gene id: 446471:XCEL_RS12655
uniprot id: D1BWI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446471:XCEL RS10825
gene id: 446471:XCEL_RS10825
uniprot id: D1BUF7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

446471:XCEL RS11290
gene id: 446471:XCEL_RS11290
uniprot id: D1BV25
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

446471:XCEL RS02065
gene id: 446471:XCEL_RS02065
uniprot id: D1BVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS01970
gene id: 446471:XCEL_RS01970
uniprot id: D1BVF7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS07795
gene id: 446471:XCEL_RS07795
uniprot id: D1BS91
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

446471:XCEL RS10205
gene id: 446471:XCEL_RS10205
uniprot id: D1BTS0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446471:XCEL RS07315
gene id: 446471:XCEL_RS07315
uniprot id: D1BRZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

446471:XCEL RS03155
gene id: 446471:XCEL_RS03155
uniprot id: D1BWT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

446471:XCEL RS09365
gene id: 446471:XCEL_RS09365
uniprot id: D1BT44
names: Similarity
messages: Belongs to the AHA1 family.

446471:XCEL RS06685
gene id: 446471:XCEL_RS06685
uniprot id: D1BRA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS02415
gene id: 446471:XCEL_RS02415
uniprot id: D1BW16
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15435
gene id: 446471:XCEL_RS15435
uniprot id: D1BZU9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06615
gene id: 446471:XCEL_RS06615
uniprot id: D1BR93
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

446471:XCEL RS00065
gene id: 446471:XCEL_RS00065
uniprot id: D1BTB0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

446471:XCEL RS05190
gene id: 446471:XCEL_RS05190
uniprot id: D1BYZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446471:XCEL RS09335
gene id: 446471:XCEL_RS09335
uniprot id: D1BT39
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

446471:XCEL RS05650
gene id: 446471:XCEL_RS05650
uniprot id: D1BZK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

446471:XCEL RS13115
gene id: 446471:XCEL_RS13115
uniprot id: D1BX50
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15515
gene id: 446471:XCEL_RS15515
uniprot id: D1BZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

446471:XCEL RS05005
gene id: 446471:XCEL_RS05005
uniprot id: D1BYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

446471:XCEL RS15875
gene id: 446471:XCEL_RS15875
uniprot id: D1C0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

446471:XCEL RS16945
gene id: 446471:XCEL_RS16945
uniprot id: D1BRW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

446471:XCEL RS04915
gene id: 446471:XCEL_RS04915
uniprot id: D1BYU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS05060
gene id: 446471:XCEL_RS05060
uniprot id: D1BYX0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06485
gene id: 446471:XCEL_RS06485
uniprot id: D1C0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

446471:XCEL RS07500
gene id: 446471:XCEL_RS07500
uniprot id: D1BS33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS12005
gene id: 446471:XCEL_RS12005
uniprot id: D1BVT4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

446471:XCEL RS15125
gene id: 446471:XCEL_RS15125
uniprot id: D1BZC1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS08325
gene id: 446471:XCEL_RS08325
uniprot id: D1BSI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446471:XCEL RS05910
gene id: 446471:XCEL_RS05910
uniprot id: D1C019
names: Similarity
messages: Belongs to the DprA/Smf family.

446471:XCEL RS12770
gene id: 446471:XCEL_RS12770
uniprot id: D1BWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03220
gene id: 446471:XCEL_RS03220
uniprot id: D1BWU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

446471:XCEL RS06410
gene id: 446471:XCEL_RS06410
uniprot id: D1C0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

446471:XCEL RS14615
gene id: 446471:XCEL_RS14615
uniprot id: D1BZ21
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS11460
gene id: 446471:XCEL_RS11460
uniprot id: D1BV58
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

446471:XCEL RS09105
gene id: 446471:XCEL_RS09105
uniprot id: D1BSZ3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446471:XCEL RS12285
gene id: 446471:XCEL_RS12285
uniprot id: D1BWB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446471:XCEL RS07955
gene id: 446471:XCEL_RS07955
uniprot id: D1BSB8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS11355
gene id: 446471:XCEL_RS11355
uniprot id: D1BV37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS16100
gene id: 446471:XCEL_RS16100
uniprot id: D1C0K3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

446471:XCEL RS05830
gene id: 446471:XCEL_RS05830
uniprot id: D1BZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446471:XCEL RS05425
gene id: 446471:XCEL_RS05425
uniprot id: D1BZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

446471:XCEL RS11995
gene id: 446471:XCEL_RS11995
uniprot id: D1BVT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

446471:XCEL RS16935
gene id: 446471:XCEL_RS16935
uniprot id: D1BRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

446471:XCEL RS03970
gene id: 446471:XCEL_RS03970
uniprot id: D1BXM0
names: Similarity
messages: Belongs to the peptidase S16 family.

446471:XCEL RS11095
gene id: 446471:XCEL_RS11095
uniprot id: D1BUY6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

446471:XCEL RS14440
gene id: 446471:XCEL_RS14440
uniprot id: D1BYK8
names: Similarity
messages: Belongs to the TPP enzyme family.

446471:XCEL RS01515
gene id: 446471:XCEL_RS01515
uniprot id: D1BUU7
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

446471:XCEL RS06710
gene id: 446471:XCEL_RS06710
uniprot id: D1BRB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS06885
gene id: 446471:XCEL_RS06885
uniprot id: D1BRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS02420
gene id: 446471:XCEL_RS02420
uniprot id: D1BW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

446471:XCEL RS05315
gene id: 446471:XCEL_RS05315
uniprot id: D1BZE2
names: Similarity
messages: Belongs to the thioredoxin family.

446471:XCEL RS07120
gene id: 446471:XCEL_RS07120
uniprot id: D1BRJ5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

446471:XCEL RS16455
gene id: 446471:XCEL_RS16455
uniprot id: D1BRK9
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

446471:XCEL RS12165
gene id: 446471:XCEL_RS12165
uniprot id: D1BW86
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

446471:XCEL RS15605
gene id: 446471:XCEL_RS15605
uniprot id: D1BZY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446471:XCEL RS02150
gene id: 446471:XCEL_RS02150
uniprot id: D1BVW2
names: Similarity
messages: Belongs to the sulfatase family.

446471:XCEL RS01630
gene id: 446471:XCEL_RS01630
uniprot id: D1BV90
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00475
gene id: 446471:XCEL_RS00475
uniprot id: D1BTX0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05705
gene id: 446471:XCEL_RS05705
uniprot id: D1BZL3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

446471:XCEL RS03905
gene id: 446471:XCEL_RS03905
uniprot id: D1BXK7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446471:XCEL RS05110
gene id: 446471:XCEL_RS05110
uniprot id: D1BYY0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

446471:XCEL RS13635
gene id: 446471:XCEL_RS13635
uniprot id: D1BXT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

446471:XCEL RS07480
gene id: 446471:XCEL_RS07480
uniprot id: D1BS29
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446471:XCEL RS16080
gene id: 446471:XCEL_RS16080
uniprot id: D1C0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

446471:XCEL RS19570
gene id: 446471:XCEL_RS19570
uniprot id: D1C0P5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

446471:XCEL RS00345
gene id: 446471:XCEL_RS00345
uniprot id: D1BTU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446471:XCEL RS07520
gene id: 446471:XCEL_RS07520
uniprot id: D1BS37
names: Similarity
messages: Belongs to the TrpC family.

446471:XCEL RS10975
gene id: 446471:XCEL_RS10975
uniprot id: D1BUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS06815
gene id: 446471:XCEL_RS06815
uniprot id: D1BRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS15810
gene id: 446471:XCEL_RS15810
uniprot id: D1C0E6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446471:XCEL RS05925
gene id: 446471:XCEL_RS05925
uniprot id: D1C022
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

446471:XCEL RS08575
gene id: 446471:XCEL_RS08575
uniprot id: D1BSN9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

446471:XCEL RS04385
gene id: 446471:XCEL_RS04385
uniprot id: D1BY66
names: Similarity
messages: Belongs to the UPF0225 family.

446471:XCEL RS00455
gene id: 446471:XCEL_RS00455
uniprot id: D1BTW5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446471:XCEL RS07610
gene id: 446471:XCEL_RS07610
uniprot id: D1BS54
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

446471:XCEL RS08480
gene id: 446471:XCEL_RS08480
uniprot id: D1BSM0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

446471:XCEL RS12765
gene id: 446471:XCEL_RS12765
uniprot id: D1BWK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS15700
gene id: 446471:XCEL_RS15700
uniprot id: D1BZZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446471:XCEL RS06585
gene id: 446471:XCEL_RS06585
uniprot id: D1BR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

446471:XCEL RS03645
gene id: 446471:XCEL_RS03645
uniprot id: D1BXF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

446471:XCEL RS08505
gene id: 446471:XCEL_RS08505
uniprot id: D1BSM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

446471:XCEL RS10640
gene id: 446471:XCEL_RS10640
uniprot id: D1BUC3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

446471:XCEL RS10810
gene id: 446471:XCEL_RS10810
uniprot id: D1BUF4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

446471:XCEL RS06465
gene id: 446471:XCEL_RS06465
uniprot id: D1C0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

446471:XCEL RS12385
gene id: 446471:XCEL_RS12385
uniprot id: D1BWD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446471:XCEL RS07170
gene id: 446471:XCEL_RS07170
uniprot id: D1BRW8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

446471:XCEL RS12230
gene id: 446471:XCEL_RS12230
uniprot id: D1BW99
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446471:XCEL RS15625
gene id: 446471:XCEL_RS15625
uniprot id: D1BZY4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

446471:XCEL RS00325
gene id: 446471:XCEL_RS00325
uniprot id: D1BTG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446471:XCEL RS07125
gene id: 446471:XCEL_RS07125
uniprot id: D1BRJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

446471:XCEL RS10125
gene id: 446471:XCEL_RS10125
uniprot id: D1BTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

446471:XCEL RS09530
gene id: 446471:XCEL_RS09530
uniprot id: D1BT71
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

446471:XCEL RS11580
gene id: 446471:XCEL_RS11580
uniprot id: D1BVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

446471:XCEL RS08375
gene id: 446471:XCEL_RS08375
uniprot id: D1BSJ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

446471:XCEL RS07260
gene id: 446471:XCEL_RS07260
uniprot id: D1BRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

446471:XCEL RS12720
gene id: 446471:XCEL_RS12720
uniprot id: D1BWJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

446471:XCEL RS05280
gene id: 446471:XCEL_RS05280
uniprot id: D1BZD5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

446471:XCEL RS04615
gene id: 446471:XCEL_RS04615
uniprot id: D1BYB1
names: Cofactor
messages: Can also use Mn(2+) ion.

446471:XCEL RS05945
gene id: 446471:XCEL_RS05945
uniprot id: D1C026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

446471:XCEL RS06065
gene id: 446471:XCEL_RS06065
uniprot id: D1C050
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

446471:XCEL RS06640
gene id: 446471:XCEL_RS06640
uniprot id: D1BR98
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

446471:XCEL RS04785
gene id: 446471:XCEL_RS04785
uniprot id: D1BYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS00040
gene id: 446471:XCEL_RS00040
uniprot id: D1BTA6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

446471:XCEL RS14985
gene id: 446471:XCEL_RS14985
uniprot id: D1BZ93
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

446471:XCEL RS05225
gene id: 446471:XCEL_RS05225
uniprot id: D1BZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS01525
gene id: 446471:XCEL_RS01525
uniprot id: D1BUU9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446471:XCEL RS00915
gene id: 446471:XCEL_RS00915
uniprot id: D1BU54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS13250
gene id: 446471:XCEL_RS13250
uniprot id: D1BX77
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

446471:XCEL RS03575
gene id: 446471:XCEL_RS03575
uniprot id: D1BXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS01365
gene id: 446471:XCEL_RS01365
uniprot id: D1BUR7
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

446471:XCEL RS11390
gene id: 446471:XCEL_RS11390
uniprot id: D1BV44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

446471:XCEL RS07450
gene id: 446471:XCEL_RS07450
uniprot id: D1BS23
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

446471:XCEL RS03120
gene id: 446471:XCEL_RS03120
uniprot id: D1BWS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446471:XCEL RS12740
gene id: 446471:XCEL_RS12740
uniprot id: D1BWK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS08390
gene id: 446471:XCEL_RS08390
uniprot id: D1BSK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446471:XCEL RS11175
gene id: 446471:XCEL_RS11175
uniprot id: D1BV02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS05210
gene id: 446471:XCEL_RS05210
uniprot id: D1BZ00
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446471:XCEL RS06330
gene id: 446471:XCEL_RS06330
uniprot id: D1C0A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

446471:XCEL RS16795
gene id: 446471:XCEL_RS16795
uniprot id: D1BRT0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

446471:XCEL RS11840
gene id: 446471:XCEL_RS11840
uniprot id: D1BVQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446471:XCEL RS07295
gene id: 446471:XCEL_RS07295
uniprot id: D1BRZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

446471:XCEL RS13240
gene id: 446471:XCEL_RS13240
uniprot id: D1BX75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12020
gene id: 446471:XCEL_RS12020
uniprot id: D1BVT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS03500
gene id: 446471:XCEL_RS03500
uniprot id: D1BXC6
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12280
gene id: 446471:XCEL_RS12280
uniprot id: D1BWA9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

446471:XCEL RS00360
gene id: 446471:XCEL_RS00360
uniprot id: D1BTU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446471:XCEL RS19530
gene id: 446471:XCEL_RS19530
uniprot id: D1BV06
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

446471:XCEL RS12405
gene id: 446471:XCEL_RS12405
uniprot id: D1BWD4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

446471:XCEL RS11945
gene id: 446471:XCEL_RS11945
uniprot id: D1BVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS16175
gene id: 446471:XCEL_RS16175
uniprot id: D1C0L8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446471:XCEL RS11235
gene id: 446471:XCEL_RS11235
uniprot id: D1BV14
names: Similarity
messages: Belongs to the YciI family.

446471:XCEL RS10870
gene id: 446471:XCEL_RS10870
uniprot id: D1BUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS15800
gene id: 446471:XCEL_RS15800
uniprot id: D1C0E4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

446471:XCEL RS03365
gene id: 446471:XCEL_RS03365
uniprot id: D1BWX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12140
gene id: 446471:XCEL_RS12140
uniprot id: D1BVV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446471:XCEL RS13985
gene id: 446471:XCEL_RS13985
uniprot id: D1BXZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS15560
gene id: 446471:XCEL_RS15560
uniprot id: D1BZX1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

446471:XCEL RS03265
gene id: 446471:XCEL_RS03265
uniprot id: D1BWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

446471:XCEL RS00395
gene id: 446471:XCEL_RS00395
uniprot id: D1BTV3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS00400
gene id: 446471:XCEL_RS00400
uniprot id: D1BTV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS03795
gene id: 446471:XCEL_RS03795
uniprot id: D1BXI6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

446471:XCEL RS08465
gene id: 446471:XCEL_RS08465
uniprot id: D1BSL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

446471:XCEL RS09150
gene id: 446471:XCEL_RS09150
uniprot id: D1BT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS03320
gene id: 446471:XCEL_RS03320
uniprot id: D1BWW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

446471:XCEL RS10745
gene id: 446471:XCEL_RS10745
uniprot id: D1BUE2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

446471:XCEL RS01975
gene id: 446471:XCEL_RS01975
uniprot id: D1BVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446471:XCEL RS11330
gene id: 446471:XCEL_RS11330
uniprot id: D1BV31
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

446471:XCEL RS07235
gene id: 446471:XCEL_RS07235
uniprot id: D1BRY1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

446471:XCEL RS09120
gene id: 446471:XCEL_RS09120
uniprot id: D1BSZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

446471:XCEL RS04675
gene id: 446471:XCEL_RS04675
uniprot id: D1BYP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

446471:XCEL RS16855
gene id: 446471:XCEL_RS16855
uniprot id: D1BRU2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

446471:XCEL RS01355
gene id: 446471:XCEL_RS01355
uniprot id: D1BUR5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446471:XCEL RS13335
gene id: 446471:XCEL_RS13335
uniprot id: D1BX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS06335
gene id: 446471:XCEL_RS06335
uniprot id: D1C0A3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

446471:XCEL RS00815
gene id: 446471:XCEL_RS00815
uniprot id: D1BU38
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05915
gene id: 446471:XCEL_RS05915
uniprot id: D1C020
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446471:XCEL RS05300
gene id: 446471:XCEL_RS05300
uniprot id: D1BZD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

446471:XCEL RS01430
gene id: 446471:XCEL_RS01430
uniprot id: D1BUT0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

446471:XCEL RS07750
gene id: 446471:XCEL_RS07750
uniprot id: D1BS82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

446471:XCEL RS08690
gene id: 446471:XCEL_RS08690
uniprot id: D1BSR2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

446471:XCEL RS05865
gene id: 446471:XCEL_RS05865
uniprot id: D1BZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

446471:XCEL RS12410
gene id: 446471:XCEL_RS12410
uniprot id: D1BWD5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

446471:XCEL RS09000
gene id: 446471:XCEL_RS09000
uniprot id: D1BSX1
names: Similarity
messages: Belongs to the IMPACT family.

446471:XCEL RS00620
gene id: 446471:XCEL_RS00620
uniprot id: D1BTZ9
names: Similarity
messages: Belongs to the peptidase C40 family.

446471:XCEL RS10065
gene id: 446471:XCEL_RS10065
uniprot id: D1BTP2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446471:XCEL RS00765
gene id: 446471:XCEL_RS00765
uniprot id: D1BU27
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS12175
gene id: 446471:XCEL_RS12175
uniprot id: D1BW88
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

446471:XCEL RS01265
gene id: 446471:XCEL_RS01265
uniprot id: D1BUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

446471:XCEL RS13160
gene id: 446471:XCEL_RS13160
uniprot id: D1BX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03020
gene id: 446471:XCEL_RS03020
uniprot id: D1BWQ9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15735
gene id: 446471:XCEL_RS15735
uniprot id: D1C006
names: Similarity
messages: Belongs to the SAICAR synthetase family.

446471:XCEL RS09490
gene id: 446471:XCEL_RS09490
uniprot id: D1BT63
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

446471:XCEL RS10630
gene id: 446471:XCEL_RS10630
uniprot id: D1BUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS09380
gene id: 446471:XCEL_RS09380
uniprot id: D1BT47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS02455
gene id: 446471:XCEL_RS02455
uniprot id: D1BW24
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05220
gene id: 446471:XCEL_RS05220
uniprot id: D1BZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS13465
gene id: 446471:XCEL_RS13465
uniprot id: D1BXP7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS07695
gene id: 446471:XCEL_RS07695
uniprot id: D1BS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

446471:XCEL RS01910
gene id: 446471:XCEL_RS01910
uniprot id: D1BVE5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446471:XCEL RS03465
gene id: 446471:XCEL_RS03465
uniprot id: D1BXB9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446471:XCEL RS12290
gene id: 446471:XCEL_RS12290
uniprot id: D1BWB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446471:XCEL RS04535
gene id: 446471:XCEL_RS04535
uniprot id: D1BY96
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

446471:XCEL RS13820
gene id: 446471:XCEL_RS13820
uniprot id: D1BXW6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS15365
gene id: 446471:XCEL_RS15365
uniprot id: D1BZT6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

446471:XCEL RS01150
gene id: 446471:XCEL_RS01150
uniprot id: D1BUM4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS13285
gene id: 446471:XCEL_RS13285
uniprot id: D1BX84
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446471:XCEL RS01275
gene id: 446471:XCEL_RS01275
uniprot id: D1BUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03740
gene id: 446471:XCEL_RS03740
uniprot id: D1BXH5
names: Similarity
messages: Belongs to the AHA1 family.

446471:XCEL RS14685
gene id: 446471:XCEL_RS14685
uniprot id: D1BZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

446471:XCEL RS04490
gene id: 446471:XCEL_RS04490
uniprot id: D1BY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS05340
gene id: 446471:XCEL_RS05340
uniprot id: D1BZE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

446471:XCEL RS17690
gene id: 446471:XCEL_RS17690
uniprot id: D1BT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

446471:XCEL RS03700
gene id: 446471:XCEL_RS03700
uniprot id: D1BXG7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

446471:XCEL RS10275
gene id: 446471:XCEL_RS10275
uniprot id: D1BTT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

446471:XCEL RS11545
gene id: 446471:XCEL_RS11545
uniprot id: D1BVJ5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

446471:XCEL RS13640
gene id: 446471:XCEL_RS13640
uniprot id: D1BXT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

446471:XCEL RS17075
gene id: 446471:XCEL_RS17075
uniprot id: D1C0T7
names: Similarity
messages: Belongs to the peptidase A24 family.

446471:XCEL RS11205
gene id: 446471:XCEL_RS11205
uniprot id: D1BV08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

446471:XCEL RS06165
gene id: 446471:XCEL_RS06165
uniprot id: D1C069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

446471:XCEL RS15635
gene id: 446471:XCEL_RS15635
uniprot id: D1BZY6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446471:XCEL RS11365
gene id: 446471:XCEL_RS11365
uniprot id: D1BV39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

446471:XCEL RS00245
gene id: 446471:XCEL_RS00245
uniprot id: D1BTE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446471:XCEL RS03415
gene id: 446471:XCEL_RS03415
uniprot id: D1BXA9
names: Similarity
messages: Belongs to the LOR family.

446471:XCEL RS10730
gene id: 446471:XCEL_RS10730
uniprot id: D1BUD9
names: Similarity
messages: Belongs to the CdaR family.

446471:XCEL RS03260
gene id: 446471:XCEL_RS03260
uniprot id: D1BWV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446471:XCEL RS15195
gene id: 446471:XCEL_RS15195
uniprot id: D1BZQ4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS13510
gene id: 446471:XCEL_RS13510
uniprot id: D1BXQ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

446471:XCEL RS08400
gene id: 446471:XCEL_RS08400
uniprot id: D1BSK4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

446471:XCEL RS17750
gene id: 446471:XCEL_RS17750
uniprot id: D1BWD9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS06245
gene id: 446471:XCEL_RS06245
uniprot id: D1C085
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

446471:XCEL RS07670
gene id: 446471:XCEL_RS07670
uniprot id: D1BS67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

446471:XCEL RS02245
gene id: 446471:XCEL_RS02245
uniprot id: D1BVY2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00980
gene id: 446471:XCEL_RS00980
uniprot id: D1BUJ0
names: Similarity
messages: Belongs to the universal stress protein A family.

446471:XCEL RS03725
gene id: 446471:XCEL_RS03725
uniprot id: D1BXH2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

446471:XCEL RS07805
gene id: 446471:XCEL_RS07805
uniprot id: D1BS93
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS05115
gene id: 446471:XCEL_RS05115
uniprot id: D1BYY1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446471:XCEL RS09535
gene id: 446471:XCEL_RS09535
uniprot id: D1BT72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS00070
gene id: 446471:XCEL_RS00070
uniprot id: D1BTB1
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15425
gene id: 446471:XCEL_RS15425
uniprot id: D1BZU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446471:XCEL RS12965
gene id: 446471:XCEL_RS12965
uniprot id: D1BX22
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

446471:XCEL RS10560
gene id: 446471:XCEL_RS10560
uniprot id: D1BUA7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446471:XCEL RS16875
gene id: 446471:XCEL_RS16875
uniprot id: D1BRU6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446471:XCEL RS12040
gene id: 446471:XCEL_RS12040
uniprot id: D1BVU0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

446471:XCEL RS16815
gene id: 446471:XCEL_RS16815
uniprot id: D1BRT4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06380
gene id: 446471:XCEL_RS06380
uniprot id: D1C0B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

446471:XCEL RS02165
gene id: 446471:XCEL_RS02165
uniprot id: D1BVW5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS04610
gene id: 446471:XCEL_RS04610
uniprot id: D1BYB0
names: Similarity
messages: Belongs to the malate synthase family.

446471:XCEL RS00665
gene id: 446471:XCEL_RS00665
uniprot id: D1BU09
names: Similarity
messages: Belongs to the UPF0303 family.

446471:XCEL RS00770
gene id: 446471:XCEL_RS00770
uniprot id: D1BU28
names: Similarity
messages: Belongs to the VapB family.

446471:XCEL RS04215
gene id: 446471:XCEL_RS04215
uniprot id: D1BY33
names: Similarity
messages: Belongs to the GSP E family.

446471:XCEL RS16830
gene id: 446471:XCEL_RS16830
uniprot id: D1BRT7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS05600
gene id: 446471:XCEL_RS05600
uniprot id: D1BZJ2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS13935
gene id: 446471:XCEL_RS13935
uniprot id: D1BXY9
names: Similarity
messages: Belongs to the SurE nucleotidase family.

446471:XCEL RS00340
gene id: 446471:XCEL_RS00340
uniprot id: D1BTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS10115
gene id: 446471:XCEL_RS10115
uniprot id: D1BTQ2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

446471:XCEL RS01815
gene id: 446471:XCEL_RS01815
uniprot id: D1BVC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446471:XCEL RS04870
gene id: 446471:XCEL_RS04870
uniprot id: D1BYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

446471:XCEL RS15010
gene id: 446471:XCEL_RS15010
uniprot id: D1BZ98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

446471:XCEL RS12400
gene id: 446471:XCEL_RS12400
uniprot id: D1BWD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

446471:XCEL RS13410
gene id: 446471:XCEL_RS13410
uniprot id: D1BXN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

446471:XCEL RS12345
gene id: 446471:XCEL_RS12345
uniprot id: D1BWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

446471:XCEL RS07535
gene id: 446471:XCEL_RS07535
uniprot id: D1BS40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

446471:XCEL RS01180
gene id: 446471:XCEL_RS01180
uniprot id: D1BUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

446471:XCEL RS12375
gene id: 446471:XCEL_RS12375
uniprot id: D1BWC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

446471:XCEL RS03280
gene id: 446471:XCEL_RS03280
uniprot id: D1BWW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

446471:XCEL RS12310
gene id: 446471:XCEL_RS12310
uniprot id: D1BWB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

446471:XCEL RS15340
gene id: 446471:XCEL_RS15340
uniprot id: D1BZT2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03555
gene id: 446471:XCEL_RS03555
uniprot id: D1BXD7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS04565
gene id: 446471:XCEL_RS04565
uniprot id: D1BYA1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446471:XCEL RS01610
gene id: 446471:XCEL_RS01610
uniprot id: D1BV86
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS02385
gene id: 446471:XCEL_RS02385
uniprot id: D1BW10
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

446471:XCEL RS12450
gene id: 446471:XCEL_RS12450
uniprot id: D1BWE2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01520
gene id: 446471:XCEL_RS01520
uniprot id: D1BUU8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03355
gene id: 446471:XCEL_RS03355
uniprot id: D1BWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

446471:XCEL RS01195
gene id: 446471:XCEL_RS01195
uniprot id: D1BUN4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

446471:XCEL RS09040
gene id: 446471:XCEL_RS09040
uniprot id: D1BSX9
names: Function
names: Similarity
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
messages: Belongs to the IucA/IucC family.

446471:XCEL RS06120
gene id: 446471:XCEL_RS06120
uniprot id: D1C060
names: Similarity
messages: Belongs to the peptidase M16 family.

446471:XCEL RS09980
gene id: 446471:XCEL_RS09980
uniprot id: D1BTM5
names: Similarity
messages: Belongs to the YciI family.

446471:XCEL RS09140
gene id: 446471:XCEL_RS09140
uniprot id: D1BT00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

446471:XCEL RS08580
gene id: 446471:XCEL_RS08580
uniprot id: D1BSP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

446471:XCEL RS05000
gene id: 446471:XCEL_RS05000
uniprot id: D1BYV8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446471:XCEL RS01000
gene id: 446471:XCEL_RS01000
uniprot id: D1BUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

446471:XCEL RS03485
gene id: 446471:XCEL_RS03485
uniprot id: D1BXC3
names: Similarity
messages: Belongs to the XFP family.

446471:XCEL RS03525
gene id: 446471:XCEL_RS03525
uniprot id: D1BXD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446471:XCEL RS18720
gene id: 446471:XCEL_RS18720
uniprot id: D1BX72
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446471:XCEL RS11335
gene id: 446471:XCEL_RS11335
uniprot id: D1BV33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

446471:XCEL RS11110
gene id: 446471:XCEL_RS11110
uniprot id: D1BUY9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15905
gene id: 446471:XCEL_RS15905
uniprot id: D1C0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS16540
gene id: 446471:XCEL_RS16540
uniprot id: D1BRM7
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

446471:XCEL RS11410
gene id: 446471:XCEL_RS11410
uniprot id: D1BV48
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12555
gene id: 446471:XCEL_RS12555
uniprot id: D1BWG3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03855
gene id: 446471:XCEL_RS03855
uniprot id: D1BXJ7
names: Similarity
messages: Belongs to the peptidase M24B family.

446471:XCEL RS14780
gene id: 446471:XCEL_RS14780
uniprot id: D1BZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

446471:XCEL RS01685
gene id: 446471:XCEL_RS01685
uniprot id: D1BVA1
names: Similarity
messages: Belongs to the peptidase M18 family.

446471:XCEL RS07300
gene id: 446471:XCEL_RS07300
uniprot id: D1BRZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS04620
gene id: 446471:XCEL_RS04620
uniprot id: D1BYB2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

446471:XCEL RS15990
gene id: 446471:XCEL_RS15990
uniprot id: D1C0I2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS10230
gene id: 446471:XCEL_RS10230
uniprot id: D1BTS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

446471:XCEL RS11595
gene id: 446471:XCEL_RS11595
uniprot id: D1BVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446471:XCEL RS14350
gene id: 446471:XCEL_RS14350
uniprot id: D1BYJ0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS15045
gene id: 446471:XCEL_RS15045
uniprot id: D1BZA5
names: Similarity
messages: Belongs to the peptidase S13 family.

446471:XCEL RS00840
gene id: 446471:XCEL_RS00840
uniprot id: D1BU43
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446471:XCEL RS06570
gene id: 446471:XCEL_RS06570
uniprot id: D1BR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

446471:XCEL RS05015
gene id: 446471:XCEL_RS05015
uniprot id: D1BYW1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446471:XCEL RS14465
gene id: 446471:XCEL_RS14465
uniprot id: D1BYL3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

446471:XCEL RS04600
gene id: 446471:XCEL_RS04600
uniprot id: D1BYA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446471:XCEL RS08595
gene id: 446471:XCEL_RS08595
uniprot id: D1BSP3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS01115
gene id: 446471:XCEL_RS01115
uniprot id: D1BUL7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446471:XCEL RS05685
gene id: 446471:XCEL_RS05685
uniprot id: D1BZK9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06025
gene id: 446471:XCEL_RS06025
uniprot id: D1C042
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS13600
gene id: 446471:XCEL_RS13600
uniprot id: D1BXS3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446471:XCEL RS03730
gene id: 446471:XCEL_RS03730
uniprot id: D1BXH3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS10945
gene id: 446471:XCEL_RS10945
uniprot id: D1BUV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

446471:XCEL RS06810
gene id: 446471:XCEL_RS06810
uniprot id: D1BRC9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05840
gene id: 446471:XCEL_RS05840
uniprot id: D1BZP0
names: Similarity
messages: Belongs to the P(II) protein family.

446471:XCEL RS07495
gene id: 446471:XCEL_RS07495
uniprot id: D1BS32
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01125
gene id: 446471:XCEL_RS01125
uniprot id: D1BUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

446471:XCEL RS10200
gene id: 446471:XCEL_RS10200
uniprot id: D1BTR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

446471:XCEL RS00530
gene id: 446471:XCEL_RS00530
uniprot id: D1BTY1
names: Similarity
messages: Belongs to the leucine-binding protein family.

446471:XCEL RS13705
gene id: 446471:XCEL_RS13705
uniprot id: D1BXU3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS07550
gene id: 446471:XCEL_RS07550
uniprot id: D1BS43
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

446471:XCEL RS15000
gene id: 446471:XCEL_RS15000
uniprot id: D1BZ96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

446471:XCEL RS03420
gene id: 446471:XCEL_RS03420
uniprot id: D1BXB0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

446471:XCEL RS03065
gene id: 446471:XCEL_RS03065
uniprot id: D1BWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

446471:XCEL RS05540
gene id: 446471:XCEL_RS05540
uniprot id: D1BZI2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

446471:XCEL RS05350
gene id: 446471:XCEL_RS05350
uniprot id: D1BZE7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS11515
gene id: 446471:XCEL_RS11515
uniprot id: D1BV69
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446471:XCEL RS05615
gene id: 446471:XCEL_RS05615
uniprot id: D1BZJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

446471:XCEL RS11270
gene id: 446471:XCEL_RS11270
uniprot id: D1BV21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446471:XCEL RS07540
gene id: 446471:XCEL_RS07540
uniprot id: D1BS41
names: Similarity
messages: Belongs to the glutamate synthase family.

446471:XCEL RS14920
gene id: 446471:XCEL_RS14920
uniprot id: D1BZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

446471:XCEL RS06030
gene id: 446471:XCEL_RS06030
uniprot id: D1C043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

446471:XCEL RS02360
gene id: 446471:XCEL_RS02360
uniprot id: D1BW05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446471:XCEL RS00160
gene id: 446471:XCEL_RS00160
uniprot id: D1BTC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS06250
gene id: 446471:XCEL_RS06250
uniprot id: D1C086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS03870
gene id: 446471:XCEL_RS03870
uniprot id: D1BXK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS15055
gene id: 446471:XCEL_RS15055
uniprot id: D1BZA7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446471:XCEL RS04210
gene id: 446471:XCEL_RS04210
uniprot id: D1BY32
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS11380
gene id: 446471:XCEL_RS11380
uniprot id: D1BV42
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

446471:XCEL RS06745
gene id: 446471:XCEL_RS06745
uniprot id: D1BRB6
names: Similarity
messages: Belongs to the TlyA family.

446471:XCEL RS05320
gene id: 446471:XCEL_RS05320
uniprot id: D1BZE3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

446471:XCEL RS02370
gene id: 446471:XCEL_RS02370
uniprot id: D1BW07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446471:XCEL RS18725
gene id: 446471:XCEL_RS18725
uniprot id: D1BX73
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS16760
gene id: 446471:XCEL_RS16760
uniprot id: D1BRS3
names: Similarity
messages: Belongs to the peptidase S33 family.

446471:XCEL RS03270
gene id: 446471:XCEL_RS03270
uniprot id: D1BWV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

446471:XCEL RS05940
gene id: 446471:XCEL_RS05940
uniprot id: D1C025
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

446471:XCEL RS05905
gene id: 446471:XCEL_RS05905
uniprot id: D1C018
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

446471:XCEL RS04705
gene id: 446471:XCEL_RS04705
uniprot id: D1BYP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

446471:XCEL RS05295
gene id: 446471:XCEL_RS05295
uniprot id: D1BZD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

446471:XCEL RS05630
gene id: 446471:XCEL_RS05630
uniprot id: D1BZJ8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446471:XCEL RS12875
gene id: 446471:XCEL_RS12875
uniprot id: D1BX04
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

446471:XCEL RS03610
gene id: 446471:XCEL_RS03610
uniprot id: D1BXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

446471:XCEL RS03625
gene id: 446471:XCEL_RS03625
uniprot id: D1BXF2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446471:XCEL RS03505
gene id: 446471:XCEL_RS03505
uniprot id: D1BXC7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01875
gene id: 446471:XCEL_RS01875
uniprot id: D1BVD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

446471:XCEL RS03780
gene id: 446471:XCEL_RS03780
uniprot id: D1BXI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS01750
gene id: 446471:XCEL_RS01750
uniprot id: D1BVB4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS06430
gene id: 446471:XCEL_RS06430
uniprot id: D1C0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

446471:XCEL RS15545
gene id: 446471:XCEL_RS15545
uniprot id: D1BZW8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06635
gene id: 446471:XCEL_RS06635
uniprot id: D1BR97
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

446471:XCEL RS03800
gene id: 446471:XCEL_RS03800
uniprot id: D1BXI7
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

446471:XCEL RS07460
gene id: 446471:XCEL_RS07460
uniprot id: D1BS25
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

446471:XCEL RS11185
gene id: 446471:XCEL_RS11185
uniprot id: D1BV04
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12635
gene id: 446471:XCEL_RS12635
uniprot id: D1BWH9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05385
gene id: 446471:XCEL_RS05385
uniprot id: D1BZF3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446471:XCEL RS05820
gene id: 446471:XCEL_RS05820
uniprot id: D1BZN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

446471:XCEL RS02345
gene id: 446471:XCEL_RS02345
uniprot id: D1BW02
names: Similarity
messages: Belongs to the isochorismate synthase family.

446471:XCEL RS16000
gene id: 446471:XCEL_RS16000
uniprot id: D1C0I4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446471:XCEL RS04975
gene id: 446471:XCEL_RS04975
uniprot id: D1BYV3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03630
gene id: 446471:XCEL_RS03630
uniprot id: D1BXF3
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

446471:XCEL RS02850
gene id: 446471:XCEL_RS02850
uniprot id: D1BWM5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

446471:XCEL RS13470
gene id: 446471:XCEL_RS13470
uniprot id: D1BXP8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS04985
gene id: 446471:XCEL_RS04985
uniprot id: D1BYV5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

446471:XCEL RS07860
gene id: 446471:XCEL_RS07860
uniprot id: D1BSA4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS09125
gene id: 446471:XCEL_RS09125
uniprot id: D1BSZ7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

446471:XCEL RS15395
gene id: 446471:XCEL_RS15395
uniprot id: D1BZU2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03185
gene id: 446471:XCEL_RS03185
uniprot id: D1BWU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

446471:XCEL RS14765
gene id: 446471:XCEL_RS14765
uniprot id: D1BZ50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

446471:XCEL RS08445
gene id: 446471:XCEL_RS08445
uniprot id: D1BSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS12800
gene id: 446471:XCEL_RS12800
uniprot id: D1BWY9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446471:XCEL RS06500
gene id: 446471:XCEL_RS06500
uniprot id: D1C0D6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

446471:XCEL RS09260
gene id: 446471:XCEL_RS09260
uniprot id: D1BT24
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS10885
gene id: 446471:XCEL_RS10885
uniprot id: D1BUG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446471:XCEL RS04260
gene id: 446471:XCEL_RS04260
uniprot id: D1BY41
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12880
gene id: 446471:XCEL_RS12880
uniprot id: D1BX05
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

446471:XCEL RS10990
gene id: 446471:XCEL_RS10990
uniprot id: D1BUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS01020
gene id: 446471:XCEL_RS01020
uniprot id: D1BUJ9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

446471:XCEL RS11450
gene id: 446471:XCEL_RS11450
uniprot id: D1BV56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

446471:XCEL RS09280
gene id: 446471:XCEL_RS09280
uniprot id: D1BT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS07270
gene id: 446471:XCEL_RS07270
uniprot id: D1BRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446471:XCEL RS03110
gene id: 446471:XCEL_RS03110
uniprot id: D1BWS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

446471:XCEL RS00600
gene id: 446471:XCEL_RS00600
uniprot id: D1BTZ5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06830
gene id: 446471:XCEL_RS06830
uniprot id: D1BRD3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

446471:XCEL RS10835
gene id: 446471:XCEL_RS10835
uniprot id: D1BUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS08615
gene id: 446471:XCEL_RS08615
uniprot id: D1BSP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446471:XCEL RS12885
gene id: 446471:XCEL_RS12885
uniprot id: D1BX06
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

446471:XCEL RS11340
gene id: 446471:XCEL_RS11340
uniprot id: D1BV34
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS02205
gene id: 446471:XCEL_RS02205
uniprot id: D1BVX4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

446471:XCEL RS11135
gene id: 446471:XCEL_RS11135
uniprot id: D1BUZ4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

446471:XCEL RS16490
gene id: 446471:XCEL_RS16490
uniprot id: D1BRL6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

446471:XCEL RS03480
gene id: 446471:XCEL_RS03480
uniprot id: D1BXC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

446471:XCEL RS15885
gene id: 446471:XCEL_RS15885
uniprot id: D1C0G1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS17810
gene id: 446471:XCEL_RS17810
uniprot id: D1BYH4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

446471:XCEL RS09045
gene id: 446471:XCEL_RS09045
uniprot id: D1BSY0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

446471:XCEL RS10290
gene id: 446471:XCEL_RS10290
uniprot id: D1BTT7
names: Similarity
messages: Belongs to the glutamine synthetase family.

446471:XCEL RS05570
gene id: 446471:XCEL_RS05570
uniprot id: D1BZI8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

446471:XCEL RS03785
gene id: 446471:XCEL_RS03785
uniprot id: D1BXI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

446471:XCEL RS06690
gene id: 446471:XCEL_RS06690
uniprot id: D1BRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

446471:XCEL RS08590
gene id: 446471:XCEL_RS08590
uniprot id: D1BSP2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

446471:XCEL RS12570
gene id: 446471:XCEL_RS12570
uniprot id: D1BWG6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

446471:XCEL RS11020
gene id: 446471:XCEL_RS11020
uniprot id: D1BUX0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

446471:XCEL RS08365
gene id: 446471:XCEL_RS08365
uniprot id: D1BSJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

446471:XCEL RS08685
gene id: 446471:XCEL_RS08685
uniprot id: D1BSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

446471:XCEL RS07475
gene id: 446471:XCEL_RS07475
uniprot id: D1BS28
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

446471:XCEL RS10050
gene id: 446471:XCEL_RS10050
uniprot id: D1BTN9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

446471:XCEL RS17825
gene id: 446471:XCEL_RS17825
uniprot id: D1BZX9
names: Subcellular Location Annotation
messages: Secreted

446471:XCEL RS16520
gene id: 446471:XCEL_RS16520
uniprot id: D1BRM2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS03380
gene id: 446471:XCEL_RS03380
uniprot id: D1BWY0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

446471:XCEL RS00200
gene id: 446471:XCEL_RS00200
uniprot id: D1BTD6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

446471:XCEL RS12755
gene id: 446471:XCEL_RS12755
uniprot id: D1BWK3
names: Similarity
messages: Belongs to the UxaA family.

446471:XCEL RS05875
gene id: 446471:XCEL_RS05875
uniprot id: D1BZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

446471:XCEL RS09005
gene id: 446471:XCEL_RS09005
uniprot id: D1BSX2
names: Similarity
messages: Belongs to the UDPGP type 1 family.

446471:XCEL RS03145
gene id: 446471:XCEL_RS03145
uniprot id: D1BWT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

446471:XCEL RS13135
gene id: 446471:XCEL_RS13135
uniprot id: D1BX54
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446471:XCEL RS04525
gene id: 446471:XCEL_RS04525
uniprot id: D1BY94
names: Similarity
messages: Belongs to the universal stress protein A family.

446471:XCEL RS00035
gene id: 446471:XCEL_RS00035
uniprot id: D1BTA5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

446471:XCEL RS08360
gene id: 446471:XCEL_RS08360
uniprot id: D1BSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

446471:XCEL RS03205
gene id: 446471:XCEL_RS03205
uniprot id: D1BWU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

446471:XCEL RS13730
gene id: 446471:XCEL_RS13730
uniprot id: D1BXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

446471:XCEL RS12835
gene id: 446471:XCEL_RS12835
uniprot id: D1BWZ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446471:XCEL RS15105
gene id: 446471:XCEL_RS15105
uniprot id: D1BZB7
names: Similarity
messages: Belongs to the UPF0045 family.

446471:XCEL RS07420
gene id: 446471:XCEL_RS07420
uniprot id: D1BS17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

446471:XCEL RS02185
gene id: 446471:XCEL_RS02185
uniprot id: D1BVW9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446471:XCEL RS04590
gene id: 446471:XCEL_RS04590
uniprot id: D1BYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS01980
gene id: 446471:XCEL_RS01980
uniprot id: D1BVF9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

446471:XCEL RS01280
gene id: 446471:XCEL_RS01280
uniprot id: D1BUQ0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS15760
gene id: 446471:XCEL_RS15760
uniprot id: D1C011
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

446471:XCEL RS11425
gene id: 446471:XCEL_RS11425
uniprot id: D1BV51
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

446471:XCEL RS16130
gene id: 446471:XCEL_RS16130
uniprot id: D1C0K9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS11320
gene id: 446471:XCEL_RS11320
uniprot id: D1BV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

446471:XCEL RS06050
gene id: 446471:XCEL_RS06050
uniprot id: D1C047
names: Similarity
messages: Belongs to the FPG family.

446471:XCEL RS13215
gene id: 446471:XCEL_RS13215
uniprot id: D1BX70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS00525
gene id: 446471:XCEL_RS00525
uniprot id: D1BTY0
names: Subcellular Location Annotation
messages: Cytoplasm

446471:XCEL RS04805
gene id: 446471:XCEL_RS04805
uniprot id: D1BYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS06480
gene id: 446471:XCEL_RS06480
uniprot id: D1C0D2
names: Similarity
messages: Belongs to the YggT family.

446471:XCEL RS15070
gene id: 446471:XCEL_RS15070
uniprot id: D1BZB0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446471:XCEL RS05725
gene id: 446471:XCEL_RS05725
uniprot id: D1BZL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS14720
gene id: 446471:XCEL_RS14720
uniprot id: D1BZ42
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

446471:XCEL RS11990
gene id: 446471:XCEL_RS11990
uniprot id: D1BVT1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS13045
gene id: 446471:XCEL_RS13045
uniprot id: D1BX36
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

446471:XCEL RS00545
gene id: 446471:XCEL_RS00545
uniprot id: D1BTY4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05155
gene id: 446471:XCEL_RS05155
uniprot id: D1BYY9
names: Similarity
messages: Belongs to the GSP E family.

446471:XCEL RS07765
gene id: 446471:XCEL_RS07765
uniprot id: D1BS85
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

446471:XCEL RS02050
gene id: 446471:XCEL_RS02050
uniprot id: D1BVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS01740
gene id: 446471:XCEL_RS01740
uniprot id: D1BVB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

446471:XCEL RS17300
gene id: 446471:XCEL_RS17300
uniprot id: D1C0Y6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

446471:XCEL RS14690
gene id: 446471:XCEL_RS14690
uniprot id: D1BZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

446471:XCEL RS14405
gene id: 446471:XCEL_RS14405
uniprot id: D1BYK1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446471:XCEL RS05195
gene id: 446471:XCEL_RS05195
uniprot id: D1BYZ7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446471:XCEL RS13740
gene id: 446471:XCEL_RS13740
uniprot id: D1BXV0
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

446471:XCEL RS11505
gene id: 446471:XCEL_RS11505
uniprot id: D1BV67
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01135
gene id: 446471:XCEL_RS01135
uniprot id: D1BUM1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446471:XCEL RS07415
gene id: 446471:XCEL_RS07415
uniprot id: D1BS16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

446471:XCEL RS00080
gene id: 446471:XCEL_RS00080
uniprot id: D1BTB3
names: Similarity
messages: Belongs to the UPF0749 family.

446471:XCEL RS12480
gene id: 446471:XCEL_RS12480
uniprot id: D1BWE8
names: Similarity
messages: Belongs to the PrpD family.

446471:XCEL RS02035
gene id: 446471:XCEL_RS02035
uniprot id: D1BVH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

446471:XCEL RS06175
gene id: 446471:XCEL_RS06175
uniprot id: D1C071
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

446471:XCEL RS14080
gene id: 446471:XCEL_RS14080
uniprot id: D1BYD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03070
gene id: 446471:XCEL_RS03070
uniprot id: D1BWR8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

446471:XCEL RS12035
gene id: 446471:XCEL_RS12035
uniprot id: D1BVT9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

446471:XCEL RS16735
gene id: 446471:XCEL_RS16735
uniprot id: D1BRR8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS11435
gene id: 446471:XCEL_RS11435
uniprot id: D1BV53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

446471:XCEL RS03605
gene id: 446471:XCEL_RS03605
uniprot id: D1BXE7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446471:XCEL RS16950
gene id: 446471:XCEL_RS16950
uniprot id: D1BRW2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

446471:XCEL RS11625
gene id: 446471:XCEL_RS11625
uniprot id: D1BVL1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

446471:XCEL RS06055
gene id: 446471:XCEL_RS06055
uniprot id: D1C048
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS15790
gene id: 446471:XCEL_RS15790
uniprot id: D1C0E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

446471:XCEL RS06260
gene id: 446471:XCEL_RS06260
uniprot id: D1C088
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446471:XCEL RS06435
gene id: 446471:XCEL_RS06435
uniprot id: D1C0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

446471:XCEL RS10100
gene id: 446471:XCEL_RS10100
uniprot id: D1BTP9
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

446471:XCEL RS13365
gene id: 446471:XCEL_RS13365
uniprot id: D1BXA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446471:XCEL RS16135
gene id: 446471:XCEL_RS16135
uniprot id: D1C0L0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS03190
gene id: 446471:XCEL_RS03190
uniprot id: D1BWU2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

446471:XCEL RS07815
gene id: 446471:XCEL_RS07815
uniprot id: D1BS95
names: Similarity
messages: Belongs to the transketolase family.

446471:XCEL RS05880
gene id: 446471:XCEL_RS05880
uniprot id: D1BZP8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

446471:XCEL RS11535
gene id: 446471:XCEL_RS11535
uniprot id: D1BV73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS08625
gene id: 446471:XCEL_RS08625
uniprot id: D1BSP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

446471:XCEL RS08370
gene id: 446471:XCEL_RS08370
uniprot id: D1BSJ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

446471:XCEL RS12335
gene id: 446471:XCEL_RS12335
uniprot id: D1BWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

446471:XCEL RS00305
gene id: 446471:XCEL_RS00305
uniprot id: D1BTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS00230
gene id: 446471:XCEL_RS00230
uniprot id: D1BTE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446471:XCEL RS08270
gene id: 446471:XCEL_RS08270
uniprot id: D1BSH8
names: Subcellular Location Annotation
messages: Cell membrane

446471:XCEL RS09205
gene id: 446471:XCEL_RS09205
uniprot id: D1BT13
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS10900
gene id: 446471:XCEL_RS10900
uniprot id: D1BUH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS02365
gene id: 446471:XCEL_RS02365
uniprot id: D1BW06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446471:XCEL RS13430
gene id: 446471:XCEL_RS13430
uniprot id: D1BXP0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

446471:XCEL RS04710
gene id: 446471:XCEL_RS04710
uniprot id: D1BYP8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

446471:XCEL RS02135
gene id: 446471:XCEL_RS02135
uniprot id: D1BVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS02080
gene id: 446471:XCEL_RS02080
uniprot id: D1BVI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

446471:XCEL RS01340
gene id: 446471:XCEL_RS01340
uniprot id: D1BUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS02195
gene id: 446471:XCEL_RS02195
uniprot id: D1BVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03130
gene id: 446471:XCEL_RS03130
uniprot id: D1BWT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

446471:XCEL RS05260
gene id: 446471:XCEL_RS05260
uniprot id: D1BZ10
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446471:XCEL RS07485
gene id: 446471:XCEL_RS07485
uniprot id: D1BS30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

446471:XCEL RS06845
gene id: 446471:XCEL_RS06845
uniprot id: D1BRD6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

446471:XCEL RS01335
gene id: 446471:XCEL_RS01335
uniprot id: D1BUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03170
gene id: 446471:XCEL_RS03170
uniprot id: D1BWT8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

446471:XCEL RS03650
gene id: 446471:XCEL_RS03650
uniprot id: D1BXF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

446471:XCEL RS15065
gene id: 446471:XCEL_RS15065
uniprot id: D1BZA9
names: Similarity
messages: Belongs to the peptidase C40 family.

446471:XCEL RS16420
gene id: 446471:XCEL_RS16420
uniprot id: D1BRK2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

446471:XCEL RS13725
gene id: 446471:XCEL_RS13725
uniprot id: D1BXU7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

446471:XCEL RS05870
gene id: 446471:XCEL_RS05870
uniprot id: D1BZP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

446471:XCEL RS08255
gene id: 446471:XCEL_RS08255
uniprot id: D1BSH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

446471:XCEL RS04880
gene id: 446471:XCEL_RS04880
uniprot id: D1BYT3
names: Similarity
messages: Belongs to the LOG family.

446471:XCEL RS10930
gene id: 446471:XCEL_RS10930
uniprot id: D1BUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446471:XCEL RS12465
gene id: 446471:XCEL_RS12465
uniprot id: D1BWE5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS16570
gene id: 446471:XCEL_RS16570
uniprot id: D1BRN3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

446471:XCEL RS13855
gene id: 446471:XCEL_RS13855
uniprot id: D1BXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS13850
gene id: 446471:XCEL_RS13850
uniprot id: D1BXX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS06565
gene id: 446471:XCEL_RS06565
uniprot id: D1BR83
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

446471:XCEL RS04625
gene id: 446471:XCEL_RS04625
uniprot id: D1BYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

446471:XCEL RS03440
gene id: 446471:XCEL_RS03440
uniprot id: D1BXB4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446471:XCEL RS00900
gene id: 446471:XCEL_RS00900
uniprot id: D1BU51
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

446471:XCEL RS08165
gene id: 446471:XCEL_RS08165
uniprot id: D1BSF8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446471:XCEL RS17415
gene id: 446471:XCEL_RS17415
uniprot id: D1C111
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

446471:XCEL RS11015
gene id: 446471:XCEL_RS11015
uniprot id: D1BUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

446471:XCEL RS12125
gene id: 446471:XCEL_RS12125
uniprot id: D1BVV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS10820
gene id: 446471:XCEL_RS10820
uniprot id: D1BUF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446471:XCEL RS11360
gene id: 446471:XCEL_RS11360
uniprot id: D1BV38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

446471:XCEL RS09520
gene id: 446471:XCEL_RS09520
uniprot id: D1BT69
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446471:XCEL RS15755
gene id: 446471:XCEL_RS15755
uniprot id: D1C010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS13790
gene id: 446471:XCEL_RS13790
uniprot id: D1BXW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

446471:XCEL RS12505
gene id: 446471:XCEL_RS12505
uniprot id: D1BWF3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00115
gene id: 446471:XCEL_RS00115
uniprot id: D1BTC0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS02125
gene id: 446471:XCEL_RS02125
uniprot id: D1BVI9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS14410
gene id: 446471:XCEL_RS14410
uniprot id: D1BYK2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

446471:XCEL RS00240
gene id: 446471:XCEL_RS00240
uniprot id: D1BTE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446471:XCEL RS15335
gene id: 446471:XCEL_RS15335
uniprot id: D1BZT1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS12485
gene id: 446471:XCEL_RS12485
uniprot id: D1BWE9
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

446471:XCEL RS08355
gene id: 446471:XCEL_RS08355
uniprot id: D1BSJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

446471:XCEL RS07985
gene id: 446471:XCEL_RS07985
uniprot id: D1BSC5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS03385
gene id: 446471:XCEL_RS03385
uniprot id: D1BWY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

446471:XCEL RS00830
gene id: 446471:XCEL_RS00830
uniprot id: D1BU41
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

446471:XCEL RS09555
gene id: 446471:XCEL_RS09555
uniprot id: D1BT76
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

446471:XCEL RS06670
gene id: 446471:XCEL_RS06670
uniprot id: D1BRA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

446471:XCEL RS12275
gene id: 446471:XCEL_RS12275
uniprot id: D1BWA8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

446471:XCEL RS13805
gene id: 446471:XCEL_RS13805
uniprot id: D1BXW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

446471:XCEL RS14360
gene id: 446471:XCEL_RS14360
uniprot id: D1BYJ2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446471:XCEL RS08905
gene id: 446471:XCEL_RS08905
uniprot id: D1BSV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

446471:XCEL RS10580
gene id: 446471:XCEL_RS10580
uniprot id: D1BUB1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

446471:XCEL RS17695
gene id: 446471:XCEL_RS17695
uniprot id: D1BT23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS02300
gene id: 446471:XCEL_RS02300
uniprot id: D1BVZ3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

446471:XCEL RS00880
gene id: 446471:XCEL_RS00880
uniprot id: D1BU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

446471:XCEL RS04960
gene id: 446471:XCEL_RS04960
uniprot id: D1BYV0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

446471:XCEL RS16160
gene id: 446471:XCEL_RS16160
uniprot id: D1C0L5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05495
gene id: 446471:XCEL_RS05495
uniprot id: D1BZH3
names: Similarity
messages: Belongs to the type IB topoisomerase family.

446471:XCEL RS09060
gene id: 446471:XCEL_RS09060
uniprot id: D1BSY3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03330
gene id: 446471:XCEL_RS03330
uniprot id: D1BWX0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

446471:XCEL RS01600
gene id: 446471:XCEL_RS01600
uniprot id: D1BV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

446471:XCEL RS15740
gene id: 446471:XCEL_RS15740
uniprot id: D1C007
names: Similarity
messages: Belongs to the GARS family.

446471:XCEL RS10850
gene id: 446471:XCEL_RS10850
uniprot id: D1BUG2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

446471:XCEL RS14535
gene id: 446471:XCEL_RS14535
uniprot id: D1BYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

446471:XCEL RS03150
gene id: 446471:XCEL_RS03150
uniprot id: D1BWT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

446471:XCEL RS08710
gene id: 446471:XCEL_RS08710
uniprot id: D1BSR6
names: Similarity
messages: Belongs to the UPF0749 family.

446471:XCEL RS06170
gene id: 446471:XCEL_RS06170
uniprot id: D1C070
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446471:XCEL RS15580
gene id: 446471:XCEL_RS15580
uniprot id: D1BZX5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00800
gene id: 446471:XCEL_RS00800
uniprot id: D1BU35
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

446471:XCEL RS03460
gene id: 446471:XCEL_RS03460
uniprot id: D1BXB8
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

446471:XCEL RS05525
gene id: 446471:XCEL_RS05525
uniprot id: D1BZH9
names: Similarity
messages: Belongs to the peptidase M1 family.

446471:XCEL RS09910
gene id: 446471:XCEL_RS09910
uniprot id: D1BTL0
names: Similarity
messages: Belongs to the CsoR family.

446471:XCEL RS12015
gene id: 446471:XCEL_RS12015
uniprot id: D1BVT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS10960
gene id: 446471:XCEL_RS10960
uniprot id: D1BUV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS15470
gene id: 446471:XCEL_RS15470
uniprot id: D1BZV6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

446471:XCEL RS06560
gene id: 446471:XCEL_RS06560
uniprot id: D1BR82
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

446471:XCEL RS13885
gene id: 446471:XCEL_RS13885
uniprot id: D1BXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS04730
gene id: 446471:XCEL_RS04730
uniprot id: D1BYQ2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

446471:XCEL RS06495
gene id: 446471:XCEL_RS06495
uniprot id: D1C0D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

446471:XCEL RS13525
gene id: 446471:XCEL_RS13525
uniprot id: D1BXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

446471:XCEL RS06800
gene id: 446471:XCEL_RS06800
uniprot id: D1BRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS06475
gene id: 446471:XCEL_RS06475
uniprot id: D1C0D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

446471:XCEL RS13210
gene id: 446471:XCEL_RS13210
uniprot id: D1BX69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

446471:XCEL RS08665
gene id: 446471:XCEL_RS08665
uniprot id: D1BSQ7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

446471:XCEL RS05765
gene id: 446471:XCEL_RS05765
uniprot id: D1BZM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

446471:XCEL RS18615
gene id: 446471:XCEL_RS18615
uniprot id: D1BSV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

446471:XCEL RS02000
gene id: 446471:XCEL_RS02000
uniprot id: D1BVG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

446471:XCEL RS08780
gene id: 446471:XCEL_RS08780
uniprot id: D1BSS9
names: Similarity
messages: Belongs to the peptidase S51 family.

446471:XCEL RS05860
gene id: 446471:XCEL_RS05860
uniprot id: D1BZP4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

446471:XCEL RS11525
gene id: 446471:XCEL_RS11525
uniprot id: D1BV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

446471:XCEL RS00835
gene id: 446471:XCEL_RS00835
uniprot id: D1BU42
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

446471:XCEL RS08610
gene id: 446471:XCEL_RS08610
uniprot id: D1BSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

446471:XCEL RS03940
gene id: 446471:XCEL_RS03940
uniprot id: D1BXL4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446471:XCEL RS04495
gene id: 446471:XCEL_RS04495
uniprot id: D1BY88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS04760
gene id: 446471:XCEL_RS04760
uniprot id: D1BYQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS07530
gene id: 446471:XCEL_RS07530
uniprot id: D1BS39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

446471:XCEL RS03285
gene id: 446471:XCEL_RS03285
uniprot id: D1BWW1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

446471:XCEL RS07780
gene id: 446471:XCEL_RS07780
uniprot id: D1BS88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

446471:XCEL RS06970
gene id: 446471:XCEL_RS06970
uniprot id: D1BRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446471:XCEL RS14070
gene id: 446471:XCEL_RS14070
uniprot id: D1BYD5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS04325
gene id: 446471:XCEL_RS04325
uniprot id: D1BY54
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS07770
gene id: 446471:XCEL_RS07770
uniprot id: D1BS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

446471:XCEL RS10475
gene id: 446471:XCEL_RS10475
uniprot id: D1BU90
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

446471:XCEL RS07110
gene id: 446471:XCEL_RS07110
uniprot id: D1BRJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

446471:XCEL RS05160
gene id: 446471:XCEL_RS05160
uniprot id: D1BYZ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

446471:XCEL RS12700
gene id: 446471:XCEL_RS12700
uniprot id: D1BWJ2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS08990
gene id: 446471:XCEL_RS08990
uniprot id: D1BSW9
names: Similarity
messages: Belongs to the Dps family.

446471:XCEL RS05500
gene id: 446471:XCEL_RS05500
uniprot id: D1BZH4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

446471:XCEL RS00075
gene id: 446471:XCEL_RS00075
uniprot id: D1BTB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

446471:XCEL RS08460
gene id: 446471:XCEL_RS08460
uniprot id: D1BSL6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

446471:XCEL RS13880
gene id: 446471:XCEL_RS13880
uniprot id: D1BXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS14175
gene id: 446471:XCEL_RS14175
uniprot id: D1BYF5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

446471:XCEL RS06425
gene id: 446471:XCEL_RS06425
uniprot id: D1C0C1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS05235
gene id: 446471:XCEL_RS05235
uniprot id: D1BZ05
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS10845
gene id: 446471:XCEL_RS10845
uniprot id: D1BUG1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

446471:XCEL RS09740
gene id: 446471:XCEL_RS09740
uniprot id: D1BTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

446471:XCEL RS03225
gene id: 446471:XCEL_RS03225
uniprot id: D1BWU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

446471:XCEL RS15090
gene id: 446471:XCEL_RS15090
uniprot id: D1BZB4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS05120
gene id: 446471:XCEL_RS05120
uniprot id: D1BYY2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446471:XCEL RS03350
gene id: 446471:XCEL_RS03350
uniprot id: D1BWX4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS15705
gene id: 446471:XCEL_RS15705
uniprot id: D1C000
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446471:XCEL RS16270
gene id: 446471:XCEL_RS16270
uniprot id: D1C0N5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446471:XCEL RS05020
gene id: 446471:XCEL_RS05020
uniprot id: D1BYW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

446471:XCEL RS14880
gene id: 446471:XCEL_RS14880
uniprot id: D1BZ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS10895
gene id: 446471:XCEL_RS10895
uniprot id: D1BUH1
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS02170
gene id: 446471:XCEL_RS02170
uniprot id: D1BVW6
names: Similarity
messages: Belongs to the histone deacetylase family.

446471:XCEL RS11255
gene id: 446471:XCEL_RS11255
uniprot id: D1BV18
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS09550
gene id: 446471:XCEL_RS09550
uniprot id: D1BT75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

446471:XCEL RS13480
gene id: 446471:XCEL_RS13480
uniprot id: D1BXP9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

446471:XCEL RS03240
gene id: 446471:XCEL_RS03240
uniprot id: D1BWV2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

446471:XCEL RS06080
gene id: 446471:XCEL_RS06080
uniprot id: D1C053
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

446471:XCEL RS11500
gene id: 446471:XCEL_RS11500
uniprot id: D1BV66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

446471:XCEL RS15995
gene id: 446471:XCEL_RS15995
uniprot id: D1C0I3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS09250
gene id: 446471:XCEL_RS09250
uniprot id: D1BT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS02410
gene id: 446471:XCEL_RS02410
uniprot id: D1BW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446471:XCEL RS15190
gene id: 446471:XCEL_RS15190
uniprot id: D1BZQ3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS04850
gene id: 446471:XCEL_RS04850
uniprot id: D1BYS7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS10535
gene id: 446471:XCEL_RS10535
uniprot id: D1BUA2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

446471:XCEL RS09760
gene id: 446471:XCEL_RS09760
uniprot id: D1BTI0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

446471:XCEL RS15930
gene id: 446471:XCEL_RS15930
uniprot id: D1C0G9
names: Similarity
messages: Belongs to the peptidase S1 family.

446471:XCEL RS06295
gene id: 446471:XCEL_RS06295
uniprot id: D1C095
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS14195
gene id: 446471:XCEL_RS14195
uniprot id: D1BYF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

446471:XCEL RS07810
gene id: 446471:XCEL_RS07810
uniprot id: D1BS94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

446471:XCEL RS04555
gene id: 446471:XCEL_RS04555
uniprot id: D1BY99
names: Similarity
messages: Belongs to the SufE family.

446471:XCEL RS12380
gene id: 446471:XCEL_RS12380
uniprot id: D1BWC9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

446471:XCEL RS13520
gene id: 446471:XCEL_RS13520
uniprot id: D1BXQ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446471:XCEL RS16720
gene id: 446471:XCEL_RS16720
uniprot id: D1BRR3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS14855
gene id: 446471:XCEL_RS14855
uniprot id: D1BZ67
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

446471:XCEL RS11000
gene id: 446471:XCEL_RS11000
uniprot id: D1BUW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

446471:XCEL RS03235
gene id: 446471:XCEL_RS03235
uniprot id: D1BWV1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

446471:XCEL RS11980
gene id: 446471:XCEL_RS11980
uniprot id: D1BVS9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS14830
gene id: 446471:XCEL_RS14830
uniprot id: D1BZ62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS06180
gene id: 446471:XCEL_RS06180
uniprot id: D1C072
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

446471:XCEL RS01955
gene id: 446471:XCEL_RS01955
uniprot id: D1BVF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS10170
gene id: 446471:XCEL_RS10170
uniprot id: D1BTR3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446471:XCEL RS10720
gene id: 446471:XCEL_RS10720
uniprot id: D1BUD7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

446471:XCEL RS05535
gene id: 446471:XCEL_RS05535
uniprot id: D1BZI1
names: Similarity
messages: Belongs to the peptidase M13 family.

446471:XCEL RS06365
gene id: 446471:XCEL_RS06365
uniprot id: D1C0A9
names: Subcellular Location Annotation
messages: Cytoplasm

446471:XCEL RS01050
gene id: 446471:XCEL_RS01050
uniprot id: D1BUK5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

446471:XCEL RS15795
gene id: 446471:XCEL_RS15795
uniprot id: D1C0E3
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

446471:XCEL RS13745
gene id: 446471:XCEL_RS13745
uniprot id: D1BXV1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

446471:XCEL RS15450
gene id: 446471:XCEL_RS15450
uniprot id: D1BZV2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446471:XCEL RS06315
gene id: 446471:XCEL_RS06315
uniprot id: D1C099
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS06775
gene id: 446471:XCEL_RS06775
uniprot id: D1BRC2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS03290
gene id: 446471:XCEL_RS03290
uniprot id: D1BWW2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

446471:XCEL RS09410
gene id: 446471:XCEL_RS09410
uniprot id: D1BT52
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS15005
gene id: 446471:XCEL_RS15005
uniprot id: D1BZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

446471:XCEL RS13180
gene id: 446471:XCEL_RS13180
uniprot id: D1BX63
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446471:XCEL RS08425
gene id: 446471:XCEL_RS08425
uniprot id: D1BSK9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

446471:XCEL RS11835
gene id: 446471:XCEL_RS11835
uniprot id: D1BVQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446471:XCEL RS11400
gene id: 446471:XCEL_RS11400
uniprot id: D1BV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

446471:XCEL RS11155
gene id: 446471:XCEL_RS11155
uniprot id: D1BUZ8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

446471:XCEL RS10015
gene id: 446471:XCEL_RS10015
uniprot id: D1BTN2
names: Similarity
messages: Belongs to the universal stress protein A family.

446471:XCEL RS08930
gene id: 446471:XCEL_RS08930
uniprot id: D1BSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446471:XCEL RS06540
gene id: 446471:XCEL_RS06540
uniprot id: D1BR78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

446471:XCEL RS03210
gene id: 446471:XCEL_RS03210
uniprot id: D1BWU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

446471:XCEL RS03080
gene id: 446471:XCEL_RS03080
uniprot id: D1BWS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

446471:XCEL RS06630
gene id: 446471:XCEL_RS06630
uniprot id: D1BR96
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

446471:XCEL RS15035
gene id: 446471:XCEL_RS15035
uniprot id: D1BZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS19020
gene id: 446471:XCEL_RS19020
uniprot id: D1C0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

446471:XCEL RS08630
gene id: 446471:XCEL_RS08630
uniprot id: D1BSQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS03075
gene id: 446471:XCEL_RS03075
uniprot id: D1BWR9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446471:XCEL RS03305
gene id: 446471:XCEL_RS03305
uniprot id: D1BWW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS09640
gene id: 446471:XCEL_RS09640
uniprot id: D1BT93
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS08435
gene id: 446471:XCEL_RS08435
uniprot id: D1BSL1
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

446471:XCEL RS03450
gene id: 446471:XCEL_RS03450
uniprot id: D1BXB6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

446471:XCEL RS09035
gene id: 446471:XCEL_RS09035
uniprot id: D1BSX8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

446471:XCEL RS02295
gene id: 446471:XCEL_RS02295
uniprot id: D1BVZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS02525
gene id: 446471:XCEL_RS02525
uniprot id: D1BW38
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

446471:XCEL RS16255
gene id: 446471:XCEL_RS16255
uniprot id: D1C0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS08675
gene id: 446471:XCEL_RS08675
uniprot id: D1BSQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

446471:XCEL RS16485
gene id: 446471:XCEL_RS16485
uniprot id: D1BRL5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

446471:XCEL RS09620
gene id: 446471:XCEL_RS09620
uniprot id: D1BT89
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

446471:XCEL RS06225
gene id: 446471:XCEL_RS06225
uniprot id: D1C081
names: Similarity
messages: Belongs to the FPG family.

446471:XCEL RS09340
gene id: 446471:XCEL_RS09340
uniprot id: D1BT40
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06255
gene id: 446471:XCEL_RS06255
uniprot id: D1C087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS09730
gene id: 446471:XCEL_RS09730
uniprot id: D1BTH4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

446471:XCEL RS14895
gene id: 446471:XCEL_RS14895
uniprot id: D1BZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS16900
gene id: 446471:XCEL_RS16900
uniprot id: D1BRV2
names: Similarity
messages: Belongs to the thioredoxin family.

446471:XCEL RS03140
gene id: 446471:XCEL_RS03140
uniprot id: D1BWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

446471:XCEL RS01060
gene id: 446471:XCEL_RS01060
uniprot id: D1BUK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446471:XCEL RS07820
gene id: 446471:XCEL_RS07820
uniprot id: D1BS96
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

446471:XCEL RS03325
gene id: 446471:XCEL_RS03325
uniprot id: D1BWW9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

446471:XCEL RS07655
gene id: 446471:XCEL_RS07655
uniprot id: D1BS64
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS08890
gene id: 446471:XCEL_RS08890
uniprot id: D1BSU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

446471:XCEL RS00550
gene id: 446471:XCEL_RS00550
uniprot id: D1BTY5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12145
gene id: 446471:XCEL_RS12145
uniprot id: D1BVV8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446471:XCEL RS05970
gene id: 446471:XCEL_RS05970
uniprot id: D1C031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS12950
gene id: 446471:XCEL_RS12950
uniprot id: D1BX19
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS10030
gene id: 446471:XCEL_RS10030
uniprot id: D1BTN5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446471:XCEL RS00930
gene id: 446471:XCEL_RS00930
uniprot id: D1BUI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

446471:XCEL RS12190
gene id: 446471:XCEL_RS12190
uniprot id: D1BW91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

446471:XCEL RS15385
gene id: 446471:XCEL_RS15385
uniprot id: D1BZU0
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

446471:XCEL RS02530
gene id: 446471:XCEL_RS02530
uniprot id: D1BW39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

446471:XCEL RS05850
gene id: 446471:XCEL_RS05850
uniprot id: D1BZP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446471:XCEL RS04265
gene id: 446471:XCEL_RS04265
uniprot id: D1BY42
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS04935
gene id: 446471:XCEL_RS04935
uniprot id: D1BYU4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

446471:XCEL RS06660
gene id: 446471:XCEL_RS06660
uniprot id: D1BRA2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

446471:XCEL RS04315
gene id: 446471:XCEL_RS04315
uniprot id: D1BY52
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS09240
gene id: 446471:XCEL_RS09240
uniprot id: D1BT20
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446471:XCEL RS01940
gene id: 446471:XCEL_RS01940
uniprot id: D1BVF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12625
gene id: 446471:XCEL_RS12625
uniprot id: D1BWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

446471:XCEL RS15780
gene id: 446471:XCEL_RS15780
uniprot id: D1C015
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

446471:XCEL RS01770
gene id: 446471:XCEL_RS01770
uniprot id: D1BVB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

446471:XCEL RS14710
gene id: 446471:XCEL_RS14710
uniprot id: D1BZ40
names: Subcellular Location Annotation
messages: Cytoplasm

446471:XCEL RS08935
gene id: 446471:XCEL_RS08935
uniprot id: D1BSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446471:XCEL RS03135
gene id: 446471:XCEL_RS03135
uniprot id: D1BWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

446471:XCEL RS03095
gene id: 446471:XCEL_RS03095
uniprot id: D1BWS3
names: Similarity
messages: Belongs to the peptidase S8 family.

446471:XCEL RS10585
gene id: 446471:XCEL_RS10585
uniprot id: D1BUB2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446471:XCEL RS13340
gene id: 446471:XCEL_RS13340
uniprot id: D1BX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS11570
gene id: 446471:XCEL_RS11570
uniprot id: D1BVK0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS07190
gene id: 446471:XCEL_RS07190
uniprot id: D1BRX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446471:XCEL RS09015
gene id: 446471:XCEL_RS09015
uniprot id: D1BSX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446471:XCEL RS07740
gene id: 446471:XCEL_RS07740
uniprot id: D1BS80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

446471:XCEL RS03975
gene id: 446471:XCEL_RS03975
uniprot id: D1BXM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

446471:XCEL RS04505
gene id: 446471:XCEL_RS04505
uniprot id: D1BY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

446471:XCEL RS15050
gene id: 446471:XCEL_RS15050
uniprot id: D1BZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

446471:XCEL RS10815
gene id: 446471:XCEL_RS10815
uniprot id: D1BUF5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00510
gene id: 446471:XCEL_RS00510
uniprot id: D1BTX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS15160
gene id: 446471:XCEL_RS15160
uniprot id: D1BZC8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS06680
gene id: 446471:XCEL_RS06680
uniprot id: D1BRA6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS00020
gene id: 446471:XCEL_RS00020
uniprot id: D1BTA2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

446471:XCEL RS15825
gene id: 446471:XCEL_RS15825
uniprot id: D1C0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS10955
gene id: 446471:XCEL_RS10955
uniprot id: D1BUV7
names: Similarity
messages: Belongs to the peptidase S14 family.

446471:XCEL RS12325
gene id: 446471:XCEL_RS12325
uniprot id: D1BWB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

446471:XCEL RS15910
gene id: 446471:XCEL_RS15910
uniprot id: D1C0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS07620
gene id: 446471:XCEL_RS07620
uniprot id: D1BS56
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06750
gene id: 446471:XCEL_RS06750
uniprot id: D1BRB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12095
gene id: 446471:XCEL_RS12095
uniprot id: D1BVU8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446471:XCEL RS03230
gene id: 446471:XCEL_RS03230
uniprot id: D1BWV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

446471:XCEL RS07830
gene id: 446471:XCEL_RS07830
uniprot id: D1BS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446471:XCEL RS06440
gene id: 446471:XCEL_RS06440
uniprot id: D1C0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

446471:XCEL RS03000
gene id: 446471:XCEL_RS03000
uniprot id: D1BWQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

446471:XCEL RS08715
gene id: 446471:XCEL_RS08715
uniprot id: D1BSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

446471:XCEL RS03715
gene id: 446471:XCEL_RS03715
uniprot id: D1BXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446471:XCEL RS01925
gene id: 446471:XCEL_RS01925
uniprot id: D1BVE8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS05545
gene id: 446471:XCEL_RS05545
uniprot id: D1BZI3
names: Similarity
messages: Belongs to the FPG family.

446471:XCEL RS15520
gene id: 446471:XCEL_RS15520
uniprot id: D1BZW3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

446471:XCEL RS12990
gene id: 446471:XCEL_RS12990
uniprot id: D1BX26
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

446471:XCEL RS06115
gene id: 446471:XCEL_RS06115
uniprot id: D1C059
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

446471:XCEL RS03165
gene id: 446471:XCEL_RS03165
uniprot id: D1BWT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

446471:XCEL RS07365
gene id: 446471:XCEL_RS07365
uniprot id: D1BS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446471:XCEL RS05655
gene id: 446471:XCEL_RS05655
uniprot id: D1BZK3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446471:XCEL RS11470
gene id: 446471:XCEL_RS11470
uniprot id: D1BV60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

446471:XCEL RS16640
gene id: 446471:XCEL_RS16640
uniprot id: D1BRP7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

446471:XCEL RS08495
gene id: 446471:XCEL_RS08495
uniprot id: D1BSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

446471:XCEL RS05815
gene id: 446471:XCEL_RS05815
uniprot id: D1BZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

446471:XCEL RS01145
gene id: 446471:XCEL_RS01145
uniprot id: D1BUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

446471:XCEL RS05400
gene id: 446471:XCEL_RS05400
uniprot id: D1BZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS02305
gene id: 446471:XCEL_RS02305
uniprot id: D1BVZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

446471:XCEL RS09705
gene id: 446471:XCEL_RS09705
uniprot id: D1BTG9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12295
gene id: 446471:XCEL_RS12295
uniprot id: D1BWB2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

446471:XCEL RS14930
gene id: 446471:XCEL_RS14930
uniprot id: D1BZ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

446471:XCEL RS00810
gene id: 446471:XCEL_RS00810
uniprot id: D1BU37
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

446471:XCEL RS13780
gene id: 446471:XCEL_RS13780
uniprot id: D1BXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

446471:XCEL RS01105
gene id: 446471:XCEL_RS01105
uniprot id: D1BUL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

446471:XCEL RS00210
gene id: 446471:XCEL_RS00210
uniprot id: D1BTD8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446471:XCEL RS15670
gene id: 446471:XCEL_RS15670
uniprot id: D1BZZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

446471:XCEL RS11150
gene id: 446471:XCEL_RS11150
uniprot id: D1BUZ7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

446471:XCEL RS02350
gene id: 446471:XCEL_RS02350
uniprot id: D1BW03
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

446471:XCEL RS14330
gene id: 446471:XCEL_RS14330
uniprot id: D1BYI6
names: Similarity
messages: Belongs to the peptidase C40 family.

446471:XCEL RS17720
gene id: 446471:XCEL_RS17720
uniprot id: D1BTJ8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

446471:XCEL RS15840
gene id: 446471:XCEL_RS15840
uniprot id: D1C0F2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446471:XCEL RS13700
gene id: 446471:XCEL_RS13700
uniprot id: D1BXU2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS03775
gene id: 446471:XCEL_RS03775
uniprot id: D1BXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS02395
gene id: 446471:XCEL_RS02395
uniprot id: D1BW12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

446471:XCEL RS08660
gene id: 446471:XCEL_RS08660
uniprot id: D1BSQ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

446471:XCEL RS14035
gene id: 446471:XCEL_RS14035
uniprot id: D1BYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS03035
gene id: 446471:XCEL_RS03035
uniprot id: D1BWR2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446471:XCEL RS15320
gene id: 446471:XCEL_RS15320
uniprot id: D1BZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446471:XCEL RS02250
gene id: 446471:XCEL_RS02250
uniprot id: D1BVY3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS13840
gene id: 446471:XCEL_RS13840
uniprot id: D1BXX0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446471:XCEL RS13585
gene id: 446471:XCEL_RS13585
uniprot id: D1BXS0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12320
gene id: 446471:XCEL_RS12320
uniprot id: D1BWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

446471:XCEL RS09235
gene id: 446471:XCEL_RS09235
uniprot id: D1BT19
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05145
gene id: 446471:XCEL_RS05145
uniprot id: D1BYY7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01410
gene id: 446471:XCEL_RS01410
uniprot id: D1BUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS05150
gene id: 446471:XCEL_RS05150
uniprot id: D1BYY8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS00185
gene id: 446471:XCEL_RS00185
uniprot id: D1BTD3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

446471:XCEL RS00960
gene id: 446471:XCEL_RS00960
uniprot id: D1BUI6
names: Similarity
messages: Belongs to the HSP15 family.

446471:XCEL RS00155
gene id: 446471:XCEL_RS00155
uniprot id: D1BTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

446471:XCEL RS08110
gene id: 446471:XCEL_RS08110
uniprot id: D1BSE7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS14220
gene id: 446471:XCEL_RS14220
uniprot id: D1BYG5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS14850
gene id: 446471:XCEL_RS14850
uniprot id: D1BZ66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS02110
gene id: 446471:XCEL_RS02110
uniprot id: D1BVI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS10085
gene id: 446471:XCEL_RS10085
uniprot id: D1BTP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS16865
gene id: 446471:XCEL_RS16865
uniprot id: D1BRU4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12615
gene id: 446471:XCEL_RS12615
uniprot id: D1BWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

446471:XCEL RS03670
gene id: 446471:XCEL_RS03670
uniprot id: D1BXG1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS09750
gene id: 446471:XCEL_RS09750
uniprot id: D1BTH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

446471:XCEL RS01640
gene id: 446471:XCEL_RS01640
uniprot id: D1BV92
names: Similarity
messages: Belongs to the GSP E family.

446471:XCEL RS15805
gene id: 446471:XCEL_RS15805
uniprot id: D1C0E5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS05250
gene id: 446471:XCEL_RS05250
uniprot id: D1BZ08
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

446471:XCEL RS10750
gene id: 446471:XCEL_RS10750
uniprot id: D1BUE3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

446471:XCEL RS02215
gene id: 446471:XCEL_RS02215
uniprot id: D1BVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

446471:XCEL RS13275
gene id: 446471:XCEL_RS13275
uniprot id: D1BX82
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

446471:XCEL RS03175
gene id: 446471:XCEL_RS03175
uniprot id: D1BWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

446471:XCEL RS08155
gene id: 446471:XCEL_RS08155
uniprot id: D1BSF6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446471:XCEL RS16395
gene id: 446471:XCEL_RS16395
uniprot id: D1C0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS13190
gene id: 446471:XCEL_RS13190
uniprot id: D1BX65
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS04765
gene id: 446471:XCEL_RS04765
uniprot id: D1BYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS14335
gene id: 446471:XCEL_RS14335
uniprot id: D1BYI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS11960
gene id: 446471:XCEL_RS11960
uniprot id: D1BVS5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

446471:XCEL RS14995
gene id: 446471:XCEL_RS14995
uniprot id: D1BZ95
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

446471:XCEL RS01650
gene id: 446471:XCEL_RS01650
uniprot id: D1BV94
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS02520
gene id: 446471:XCEL_RS02520
uniprot id: D1BW37
names: Similarity
messages: Belongs to the peptidase A24 family.

446471:XCEL RS03475
gene id: 446471:XCEL_RS03475
uniprot id: D1BXC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

446471:XCEL RS11985
gene id: 446471:XCEL_RS11985
uniprot id: D1BVT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS10315
gene id: 446471:XCEL_RS10315
uniprot id: D1BU58
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

446471:XCEL RS06695
gene id: 446471:XCEL_RS06695
uniprot id: D1BRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

446471:XCEL RS03125
gene id: 446471:XCEL_RS03125
uniprot id: D1BWS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

446471:XCEL RS14320
gene id: 446471:XCEL_RS14320
uniprot id: D1BYI4
names: Similarity
messages: Belongs to the universal stress protein A family.

446471:XCEL RS03515
gene id: 446471:XCEL_RS03515
uniprot id: D1BXC9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS04575
gene id: 446471:XCEL_RS04575
uniprot id: D1BYA3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS16670
gene id: 446471:XCEL_RS16670
uniprot id: D1BRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS12265
gene id: 446471:XCEL_RS12265
uniprot id: D1BWA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

446471:XCEL RS14875
gene id: 446471:XCEL_RS14875
uniprot id: D1BZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446471:XCEL RS11480
gene id: 446471:XCEL_RS11480
uniprot id: D1BV62
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

446471:XCEL RS02265
gene id: 446471:XCEL_RS02265
uniprot id: D1BVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

446471:XCEL RS10480
gene id: 446471:XCEL_RS10480
uniprot id: D1BU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

446471:XCEL RS12330
gene id: 446471:XCEL_RS12330
uniprot id: D1BWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

446471:XCEL RS16435
gene id: 446471:XCEL_RS16435
uniprot id: D1BRK5
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

446471:XCEL RS16820
gene id: 446471:XCEL_RS16820
uniprot id: D1BRT5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

446471:XCEL RS16655
gene id: 446471:XCEL_RS16655
uniprot id: D1BRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

446471:XCEL RS01025
gene id: 446471:XCEL_RS01025
uniprot id: D1BUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

446471:XCEL RS13620
gene id: 446471:XCEL_RS13620
uniprot id: D1BXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

446471:XCEL RS06795
gene id: 446471:XCEL_RS06795
uniprot id: D1BRC6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446471:XCEL RS16885
gene id: 446471:XCEL_RS16885
uniprot id: D1BRU8
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS02130
gene id: 446471:XCEL_RS02130
uniprot id: D1BVJ0
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS14125
gene id: 446471:XCEL_RS14125
uniprot id: D1BYE5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS09050
gene id: 446471:XCEL_RS09050
uniprot id: D1BSY1
names: Similarity
messages: Belongs to the group II decarboxylase family.

446471:XCEL RS03655
gene id: 446471:XCEL_RS03655
uniprot id: D1BXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

446471:XCEL RS10605
gene id: 446471:XCEL_RS10605
uniprot id: D1BUB6
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS11370
gene id: 446471:XCEL_RS11370
uniprot id: D1BV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

446471:XCEL RS03250
gene id: 446471:XCEL_RS03250
uniprot id: D1BWV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

446471:XCEL RS15850
gene id: 446471:XCEL_RS15850
uniprot id: D1C0F4
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12000
gene id: 446471:XCEL_RS12000
uniprot id: D1BVT3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

446471:XCEL RS13245
gene id: 446471:XCEL_RS13245
uniprot id: D1BX76
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS11490
gene id: 446471:XCEL_RS11490
uniprot id: D1BV64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

446471:XCEL RS15570
gene id: 446471:XCEL_RS15570
uniprot id: D1BZX3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

446471:XCEL RS02555
gene id: 446471:XCEL_RS02555
uniprot id: D1BW44
names: Similarity
messages: Belongs to the UPF0234 family.

446471:XCEL RS05730
gene id: 446471:XCEL_RS05730
uniprot id: D1BZL8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

446471:XCEL RS14730
gene id: 446471:XCEL_RS14730
uniprot id: D1BZ44
names: Similarity
messages: Belongs to the PspA/IM30 family.

446471:XCEL RS11405
gene id: 446471:XCEL_RS11405
uniprot id: D1BV47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

446471:XCEL RS11285
gene id: 446471:XCEL_RS11285
uniprot id: D1BV24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

446471:XCEL RS11055
gene id: 446471:XCEL_RS11055
uniprot id: D1BUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

446471:XCEL RS10925
gene id: 446471:XCEL_RS10925
uniprot id: D1BUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446471:XCEL RS14275
gene id: 446471:XCEL_RS14275
uniprot id: D1BYH5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

446471:XCEL RS13625
gene id: 446471:XCEL_RS13625
uniprot id: D1BXS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

446471:XCEL RS12490
gene id: 446471:XCEL_RS12490
uniprot id: D1BWF0
names: Similarity
messages: Belongs to the citrate synthase family.

446471:XCEL RS16895
gene id: 446471:XCEL_RS16895
uniprot id: D1BRV1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

446471:XCEL RS07465
gene id: 446471:XCEL_RS07465
uniprot id: D1BS26
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

446471:XCEL RS09320
gene id: 446471:XCEL_RS09320
uniprot id: D1BT36
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS04090
gene id: 446471:XCEL_RS04090
uniprot id: D1BY10
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS09030
gene id: 446471:XCEL_RS09030
uniprot id: D1BSX7
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

446471:XCEL RS05660
gene id: 446471:XCEL_RS05660
uniprot id: D1BZK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446471:XCEL RS05370
gene id: 446471:XCEL_RS05370
uniprot id: D1BZF0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12805
gene id: 446471:XCEL_RS12805
uniprot id: D1BWZ0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

446471:XCEL RS09230
gene id: 446471:XCEL_RS09230
uniprot id: D1BT18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

446471:XCEL RS09175
gene id: 446471:XCEL_RS09175
uniprot id: D1BT07
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

446471:XCEL RS06070
gene id: 446471:XCEL_RS06070
uniprot id: D1C051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

446471:XCEL RS01760
gene id: 446471:XCEL_RS01760
uniprot id: D1BVB6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

446471:XCEL RS17145
gene id: 446471:XCEL_RS17145
uniprot id: D1C0V3
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12565
gene id: 446471:XCEL_RS12565
uniprot id: D1BWG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

446471:XCEL RS14215
gene id: 446471:XCEL_RS14215
uniprot id: D1BYG4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS07700
gene id: 446471:XCEL_RS07700
uniprot id: D1BS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

446471:XCEL RS00015
gene id: 446471:XCEL_RS00015
uniprot id: D1BTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

446471:XCEL RS00630
gene id: 446471:XCEL_RS00630
uniprot id: D1BU01
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

446471:XCEL RS01860
gene id: 446471:XCEL_RS01860
uniprot id: D1BVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS12890
gene id: 446471:XCEL_RS12890
uniprot id: D1BX07
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

446471:XCEL RS05585
gene id: 446471:XCEL_RS05585
uniprot id: D1BZI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446471:XCEL RS15175
gene id: 446471:XCEL_RS15175
uniprot id: D1BZD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

446471:XCEL RS01950
gene id: 446471:XCEL_RS01950
uniprot id: D1BVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

446471:XCEL RS15410
gene id: 446471:XCEL_RS15410
uniprot id: D1BZU4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

446471:XCEL RS17365
gene id: 446471:XCEL_RS17365
uniprot id: D1C100
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS11345
gene id: 446471:XCEL_RS11345
uniprot id: D1BV35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

446471:XCEL RS03180
gene id: 446471:XCEL_RS03180
uniprot id: D1BWU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

446471:XCEL RS08560
gene id: 446471:XCEL_RS08560
uniprot id: D1BSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

446471:XCEL RS13025
gene id: 446471:XCEL_RS13025
uniprot id: D1BX32
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446471:XCEL RS09505
gene id: 446471:XCEL_RS09505
uniprot id: D1BT66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

446471:XCEL RS10045
gene id: 446471:XCEL_RS10045
uniprot id: D1BTN8
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

446471:XCEL RS12340
gene id: 446471:XCEL_RS12340
uniprot id: D1BWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

446471:XCEL RS08490
gene id: 446471:XCEL_RS08490
uniprot id: D1BSM2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

446471:XCEL RS16475
gene id: 446471:XCEL_RS16475
uniprot id: D1BRL3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

446471:XCEL RS02070
gene id: 446471:XCEL_RS02070
uniprot id: D1BVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS07730
gene id: 446471:XCEL_RS07730
uniprot id: D1BS78
names: Similarity
messages: Belongs to the YciI family.

446471:XCEL RS12785
gene id: 446471:XCEL_RS12785
uniprot id: D1BWY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

446471:XCEL RS12420
gene id: 446471:XCEL_RS12420
uniprot id: D1BWD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS01370
gene id: 446471:XCEL_RS01370
uniprot id: D1BUR8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446471:XCEL RS16375
gene id: 446471:XCEL_RS16375
uniprot id: D1C0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

446471:XCEL RS04845
gene id: 446471:XCEL_RS04845
uniprot id: D1BYS6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446471:XCEL RS06620
gene id: 446471:XCEL_RS06620
uniprot id: D1BR94
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

446471:XCEL RS16810
gene id: 446471:XCEL_RS16810
uniprot id: D1BRT3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

446471:XCEL RS13345
gene id: 446471:XCEL_RS13345
uniprot id: D1BX96
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

446471:XCEL RS04415
gene id: 446471:XCEL_RS04415
uniprot id: D1BY72
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS16010
gene id: 446471:XCEL_RS16010
uniprot id: D1C0I6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS06270
gene id: 446471:XCEL_RS06270
uniprot id: D1C090
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

446471:XCEL RS06405
gene id: 446471:XCEL_RS06405
uniprot id: D1C0B7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

446471:XCEL RS16405
gene id: 446471:XCEL_RS16405
uniprot id: D1C0R2
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS12045
gene id: 446471:XCEL_RS12045
uniprot id: D1BVU1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

446471:XCEL RS03215
gene id: 446471:XCEL_RS03215
uniprot id: D1BWU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

446471:XCEL RS09055
gene id: 446471:XCEL_RS09055
uniprot id: D1BSY2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

446471:XCEL RS11415
gene id: 446471:XCEL_RS11415
uniprot id: D1BV49
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS06445
gene id: 446471:XCEL_RS06445
uniprot id: D1C0C5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS04100
gene id: 446471:XCEL_RS04100
uniprot id: D1BY11
names: Similarity
messages: Belongs to the EccE family.

446471:XCEL RS07165
gene id: 446471:XCEL_RS07165
uniprot id: D1BRW7
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS14325
gene id: 446471:XCEL_RS14325
uniprot id: D1BYI5
names: Similarity
messages: Belongs to the peptidase C40 family.

446471:XCEL RS04790
gene id: 446471:XCEL_RS04790
uniprot id: D1BYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS07760
gene id: 446471:XCEL_RS07760
uniprot id: D1BS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

446471:XCEL RS16835
gene id: 446471:XCEL_RS16835
uniprot id: D1BRT8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

446471:XCEL RS05935
gene id: 446471:XCEL_RS05935
uniprot id: D1C024
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS14655
gene id: 446471:XCEL_RS14655
uniprot id: D1BZ29
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446471:XCEL RS04520
gene id: 446471:XCEL_RS04520
uniprot id: D1BY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

446471:XCEL RS05885
gene id: 446471:XCEL_RS05885
uniprot id: D1BZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

446471:XCEL RS12085
gene id: 446471:XCEL_RS12085
uniprot id: D1BVU6
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS13440
gene id: 446471:XCEL_RS13440
uniprot id: D1BXP2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446471:XCEL RS04390
gene id: 446471:XCEL_RS04390
uniprot id: D1BY67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446471:XCEL RS03105
gene id: 446471:XCEL_RS03105
uniprot id: D1BWS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446471:XCEL RS03200
gene id: 446471:XCEL_RS03200
uniprot id: D1BWU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

446471:XCEL RS16290
gene id: 446471:XCEL_RS16290
uniprot id: D1C0N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

446471:XCEL RS16770
gene id: 446471:XCEL_RS16770
uniprot id: D1BRS5
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS05805
gene id: 446471:XCEL_RS05805
uniprot id: D1BZN3
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

446471:XCEL RS03435
gene id: 446471:XCEL_RS03435
uniprot id: D1BXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

446471:XCEL RS11815
gene id: 446471:XCEL_RS11815
uniprot id: D1BVP9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

446471:XCEL RS07785
gene id: 446471:XCEL_RS07785
uniprot id: D1BS89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

446471:XCEL RS14905
gene id: 446471:XCEL_RS14905
uniprot id: D1BZ77
names: Similarity
messages: Belongs to the PstS family.

446471:XCEL RS06705
gene id: 446471:XCEL_RS06705
uniprot id: D1BRB1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

446471:XCEL RS11615
gene id: 446471:XCEL_RS11615
uniprot id: D1BVK9
names: Subcellular Location Annotation
messages: Membrane

446471:XCEL RS01695
gene id: 446471:XCEL_RS01695
uniprot id: D1BVA3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446471:XCEL RS09690
gene id: 446471:XCEL_RS09690
uniprot id: D1BTG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

446471:XCEL RS10855
gene id: 446471:XCEL_RS10855
uniprot id: D1BUG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446471:XCEL RS05170
gene id: 446471:XCEL_RS05170
uniprot id: D1BYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

446471:XCEL RS06240
gene id: 446471:XCEL_RS06240
uniprot id: D1C084
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

446471:XCEL RS03825
gene id: 446471:XCEL_RS03825
uniprot id: D1BXJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

446471:XCEL RS16260
gene id: 446471:XCEL_RS16260
uniprot id: D1C0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446471:XCEL RS12105
gene id: 446471:XCEL_RS12105
uniprot id: D1BVV0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

446471:XCEL RS01435
gene id: 446471:XCEL_RS01435
uniprot id: D1BUT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446471:XCEL RS12905
gene id: 446471:XCEL_RS12905
uniprot id: D1BX10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

446471:XCEL RS03025
gene id: 446471:XCEL_RS03025
uniprot id: D1BWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

446471:XCEL RS10740
gene id: 446471:XCEL_RS10740
uniprot id: D1BUE1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

446471:XCEL RS03275
gene id: 446471:XCEL_RS03275
uniprot id: D1BWV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

446471:XCEL RS07470
gene id: 446471:XCEL_RS07470
uniprot id: D1BS27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

446471:XCEL RS17140
gene id: 446471:XCEL_RS17140
uniprot id: D1C0V2
names: Similarity
messages: Belongs to the GSP E family.

446471:XCEL RS16910
gene id: 446471:XCEL_RS16910
uniprot id: D1BRV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

446471:XCEL RS08620
gene id: 446471:XCEL_RS08620
uniprot id: D1BSP8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.