221109:OB RS09200
gene id: 221109:OB_RS09200
uniprot id: Q8EQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

221109:OB RS04195
gene id: 221109:OB_RS04195
uniprot id: Q8ES64
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

221109:OB RS14960
gene id: 221109:OB_RS14960
uniprot id: Q8EMC4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

221109:OB RS09865
gene id: 221109:OB_RS09865
uniprot id: Q8EQ10
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

221109:OB RS09610
gene id: 221109:OB_RS09610
uniprot id: Q8EQ51
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

221109:OB RS03015
gene id: 221109:OB_RS03015
uniprot id: Q8ESR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS08000
gene id: 221109:OB_RS08000
uniprot id: Q8EQZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

221109:OB RS08035
gene id: 221109:OB_RS08035
uniprot id: P59386
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

221109:OB RS17680
gene id: 221109:OB_RS17680
uniprot id: Q8EKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS15190
gene id: 221109:OB_RS15190
uniprot id: Q8EM83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

221109:OB RS07290
gene id: 221109:OB_RS07290
uniprot id: Q8ERA7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11700
gene id: 221109:OB_RS11700
uniprot id: Q8CZE0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

221109:OB RS09670
gene id: 221109:OB_RS09670
uniprot id: Q8EQ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

221109:OB RS13430
gene id: 221109:OB_RS13430
uniprot id: Q8EN64
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

221109:OB RS00125
gene id: 221109:OB_RS00125
uniprot id: Q8EU66
names: Similarity
messages: Belongs to the peptidase C56 family.

221109:OB RS14905
gene id: 221109:OB_RS14905
uniprot id: Q8EMD2
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS08920
gene id: 221109:OB_RS08920
uniprot id: Q8EQH0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

221109:OB RS10705
gene id: 221109:OB_RS10705
uniprot id: Q8CXB6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

221109:OB RS09060
gene id: 221109:OB_RS09060
uniprot id: Q8EQE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS11345
gene id: 221109:OB_RS11345
uniprot id: Q8EPA5
names: Similarity
messages: Belongs to the aldose epimerase family.

221109:OB RS15805
gene id: 221109:OB_RS15805
uniprot id: Q8ELW4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

221109:OB RS09075
gene id: 221109:OB_RS09075
uniprot id: Q8EQD9
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

221109:OB RS14210
gene id: 221109:OB_RS14210
uniprot id: Q8EMQ9
names: Similarity
messages: Belongs to the catalase family.

221109:OB RS13420
gene id: 221109:OB_RS13420
uniprot id: Q8EN66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

221109:OB RS06605
gene id: 221109:OB_RS06605
uniprot id: Q8ERP3
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05060
gene id: 221109:OB_RS05060
uniprot id: Q8CV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

221109:OB RS13085
gene id: 221109:OB_RS13085
uniprot id: Q8END4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS14645
gene id: 221109:OB_RS14645
uniprot id: Q8EMH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

221109:OB RS13725
gene id: 221109:OB_RS13725
uniprot id: Q8EN08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS01525
gene id: 221109:OB_RS01525
uniprot id: Q8ETK3
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS10510
gene id: 221109:OB_RS10510
uniprot id: Q8EPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

221109:OB RS04050
gene id: 221109:OB_RS04050
uniprot id: Q8ES92
names: Similarity
messages: Belongs to the GARS family.

221109:OB RS02435
gene id: 221109:OB_RS02435
uniprot id: Q8ET21
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07705
gene id: 221109:OB_RS07705
uniprot id: Q8ER40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

221109:OB RS02550
gene id: 221109:OB_RS02550
uniprot id: Q8ESZ9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

221109:OB RS09515
gene id: 221109:OB_RS09515
uniprot id: Q8EQ64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the MPD complex composed of SpoIIM, SpoIIP and SpoIID.
messages: Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.

221109:OB RS03795
gene id: 221109:OB_RS03795
uniprot id: Q8CXK9
names: Similarity
messages: Belongs to the glutamate synthase family.

221109:OB RS11100
gene id: 221109:OB_RS11100
uniprot id: Q8EPF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

221109:OB RS10680
gene id: 221109:OB_RS10680
uniprot id: Q8EPM2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

221109:OB RS09440
gene id: 221109:OB_RS09440
uniprot id: Q8EQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

221109:OB RS02350
gene id: 221109:OB_RS02350
uniprot id: Q8ET38
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07230
gene id: 221109:OB_RS07230
uniprot id: Q8CXJ4
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

221109:OB RS11630
gene id: 221109:OB_RS11630
uniprot id: Q8EP54
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS09925
gene id: 221109:OB_RS09925
uniprot id: Q8CXD5
names: Similarity
messages: Belongs to the transpeptidase family.

221109:OB RS15650
gene id: 221109:OB_RS15650
uniprot id: Q8ELZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS00620
gene id: 221109:OB_RS00620
uniprot id: Q8EU06
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

221109:OB RS07870
gene id: 221109:OB_RS07870
uniprot id: Q8ER13
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

221109:OB RS00430
gene id: 221109:OB_RS00430
uniprot id: Q8CXP5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

221109:OB RS00375
gene id: 221109:OB_RS00375
uniprot id: Q8EU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

221109:OB RS08050
gene id: 221109:OB_RS08050
uniprot id: Q8EQY4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

221109:OB RS07920
gene id: 221109:OB_RS07920
uniprot id: Q7ZAM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

221109:OB RS09935
gene id: 221109:OB_RS09935
uniprot id: Q8EPZ8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

221109:OB RS16840
gene id: 221109:OB_RS16840
uniprot id: Q8ELC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS03310
gene id: 221109:OB_RS03310
uniprot id: Q8CXM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

221109:OB RS11790
gene id: 221109:OB_RS11790
uniprot id: Q8EP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

221109:OB RS05050
gene id: 221109:OB_RS05050
uniprot id: Q8CV17
names: Similarity
messages: Belongs to the PspA/IM30 family.

221109:OB RS09555
gene id: 221109:OB_RS09555
uniprot id: Q8EQ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

221109:OB RS06560
gene id: 221109:OB_RS06560
uniprot id: Q8ERQ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS09675
gene id: 221109:OB_RS09675
uniprot id: Q8EQ42
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

221109:OB RS09895
gene id: 221109:OB_RS09895
uniprot id: Q8EQ05
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

221109:OB RS09410
gene id: 221109:OB_RS09410
uniprot id: Q7ZAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

221109:OB RS11675
gene id: 221109:OB_RS11675
uniprot id: Q8EP47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

221109:OB RS10320
gene id: 221109:OB_RS10320
uniprot id: Q8EPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

221109:OB RS12510
gene id: 221109:OB_RS12510
uniprot id: Q8ENP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

221109:OB RS07460
gene id: 221109:OB_RS07460
uniprot id: Q8ER77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

221109:OB RS06415
gene id: 221109:OB_RS06415
uniprot id: Q8ERS7
names: Function
names: Similarity
messages: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
messages: Belongs to the PrpE family.

221109:OB RS03665
gene id: 221109:OB_RS03665
uniprot id: Q8ESG8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS05740
gene id: 221109:OB_RS05740
uniprot id: Q8CUM6
names: Similarity
messages: Belongs to the peptidase S9C family.

221109:OB RS10445
gene id: 221109:OB_RS10445
uniprot id: Q8CXC5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11735
gene id: 221109:OB_RS11735
uniprot id: Q8EP37
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS02155
gene id: 221109:OB_RS02155
uniprot id: Q8ET76
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

221109:OB RS17475
gene id: 221109:OB_RS17475
uniprot id: Q8EL02
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

221109:OB RS07365
gene id: 221109:OB_RS07365
uniprot id: Q8CXJ1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

221109:OB RS03695
gene id: 221109:OB_RS03695
uniprot id: Q8ESG3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

221109:OB RS03320
gene id: 221109:OB_RS03320
uniprot id: Q8ESK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

221109:OB RS17465
gene id: 221109:OB_RS17465
uniprot id: Q8EL04
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity).
messages: Homohexamer.
messages: In this second copy of HPRK/P in O.iheyensis, Ala-202 and Glu-243 are present instead of the conserved Glu and Arg which are respectively expected to be part of the active site.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

221109:OB RS08965
gene id: 221109:OB_RS08965
uniprot id: Q8EQG1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

221109:OB RS04030
gene id: 221109:OB_RS04030
uniprot id: Q8ES95
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

221109:OB RS07580
gene id: 221109:OB_RS07580
uniprot id: Q8ER55
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

221109:OB RS09430
gene id: 221109:OB_RS09430
uniprot id: Q8CXF1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

221109:OB RS05830
gene id: 221109:OB_RS05830
uniprot id: Q8CUK8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15275
gene id: 221109:OB_RS15275
uniprot id: Q8EM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

221109:OB RS06325
gene id: 221109:OB_RS06325
uniprot id: Q8ERU5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

221109:OB RS07060
gene id: 221109:OB_RS07060
uniprot id: Q8ERF4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

221109:OB RS05825
gene id: 221109:OB_RS05825
uniprot id: Q8CUK9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07770
gene id: 221109:OB_RS07770
uniprot id: Q8ER32
names: Similarity
messages: Belongs to the OsmC/Ohr family.

221109:OB RS17760
gene id: 221109:OB_RS17760
uniprot id: Q8EKU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ParB family.
messages: Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
messages: nucleoid

221109:OB RS06800
gene id: 221109:OB_RS06800
uniprot id: Q8ERK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS02255
gene id: 221109:OB_RS02255
uniprot id: Q8CZE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

221109:OB RS00090
gene id: 221109:OB_RS00090
uniprot id: Q8EU73
names: Similarity
messages: Belongs to the DCK/DGK family.

221109:OB RS09370
gene id: 221109:OB_RS09370
uniprot id: Q8EQ89
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS09595
gene id: 221109:OB_RS09595
uniprot id: Q8CXE7
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

221109:OB RS11115
gene id: 221109:OB_RS11115
uniprot id: Q8EPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

221109:OB RS08045
gene id: 221109:OB_RS08045
uniprot id: Q8EQY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

221109:OB RS01545
gene id: 221109:OB_RS01545
uniprot id: Q8ETJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS11150
gene id: 221109:OB_RS11150
uniprot id: Q8EPE0
names: Similarity
messages: Belongs to the citrate synthase family.

221109:OB RS14225
gene id: 221109:OB_RS14225
uniprot id: Q8EMQ7
names: Similarity
messages: Belongs to the CdaR family.

221109:OB RS15320
gene id: 221109:OB_RS15320
uniprot id: Q8EM55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

221109:OB RS03050
gene id: 221109:OB_RS03050
uniprot id: Q8ESQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS17540
gene id: 221109:OB_RS17540
uniprot id: Q8EKY9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06030
gene id: 221109:OB_RS06030
uniprot id: Q8CUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

221109:OB RS14090
gene id: 221109:OB_RS14090
uniprot id: Q8CZD5
names: Cofactor
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Cytoplasm
messages: Heterodimer with glycerol kinase (glpk).
messages: The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport.

221109:OB RS10365
gene id: 221109:OB_RS10365
uniprot id: Q8EPS6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

221109:OB RS11585
gene id: 221109:OB_RS11585
uniprot id: Q8EP63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

221109:OB RS10315
gene id: 221109:OB_RS10315
uniprot id: Q8EPT6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

221109:OB RS10435
gene id: 221109:OB_RS10435
uniprot id: Q8EPR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

221109:OB RS10880
gene id: 221109:OB_RS10880
uniprot id: Q8EPI9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

221109:OB RS00915
gene id: 221109:OB_RS00915
uniprot id: Q8ETV3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

221109:OB RS09485
gene id: 221109:OB_RS09485
uniprot id: Q8EQ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

221109:OB RS10520
gene id: 221109:OB_RS10520
uniprot id: Q8EPP8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

221109:OB RS11470
gene id: 221109:OB_RS11470
uniprot id: Q7ZAM2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

221109:OB RS15705
gene id: 221109:OB_RS15705
uniprot id: Q8ELY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

221109:OB RS14135
gene id: 221109:OB_RS14135
uniprot id: Q8EMS4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

221109:OB RS16680
gene id: 221109:OB_RS16680
uniprot id: Q8ELF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

221109:OB RS05780
gene id: 221109:OB_RS05780
uniprot id: Q8CUL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

221109:OB RS02410
gene id: 221109:OB_RS02410
uniprot id: Q8ET26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

221109:OB RS04040
gene id: 221109:OB_RS04040
uniprot id: Q8ES93
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

221109:OB RS17360
gene id: 221109:OB_RS17360
uniprot id: Q8EL24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

221109:OB RS16825
gene id: 221109:OB_RS16825
uniprot id: Q8CX58
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

221109:OB RS14290
gene id: 221109:OB_RS14290
uniprot id: Q8EMP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

221109:OB RS09065
gene id: 221109:OB_RS09065
uniprot id: Q8EQE1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS06290
gene id: 221109:OB_RS06290
uniprot id: Q8CXK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS05410
gene id: 221109:OB_RS05410
uniprot id: Q8CUU5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

221109:OB RS09310
gene id: 221109:OB_RS09310
uniprot id: Q8EQA0
names: Similarity
messages: Belongs to the asparaginase 1 family.

221109:OB RS07885
gene id: 221109:OB_RS07885
uniprot id: Q8ER10
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

221109:OB RS06210
gene id: 221109:OB_RS06210
uniprot id: Q8ERW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

221109:OB RS12895
gene id: 221109:OB_RS12895
uniprot id: Q8ENH0
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06000
gene id: 221109:OB_RS06000
uniprot id: Q8CUH1
names: Similarity
messages: Belongs to the UPF0342 family.

221109:OB RS00605
gene id: 221109:OB_RS00605
uniprot id: Q8EU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

221109:OB RS00325
gene id: 221109:OB_RS00325
uniprot id: Q8EU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

221109:OB RS11170
gene id: 221109:OB_RS11170
uniprot id: Q8EPD6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

221109:OB RS09300
gene id: 221109:OB_RS09300
uniprot id: P59105
names: Function
names: Similarity
messages: Belongs to the SleB family.
messages: Required for spore cortex hydrolysis during germination.

221109:OB RS08160
gene id: 221109:OB_RS08160
uniprot id: Q8EQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

221109:OB RS11945
gene id: 221109:OB_RS11945
uniprot id: Q8ENZ7
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

221109:OB RS11140
gene id: 221109:OB_RS11140
uniprot id: Q8EPE2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

221109:OB RS11570
gene id: 221109:OB_RS11570
uniprot id: Q8EP66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

221109:OB RS15575
gene id: 221109:OB_RS15575
uniprot id: Q8EM07
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

221109:OB RS08710
gene id: 221109:OB_RS08710
uniprot id: Q8EQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

221109:OB RS02270
gene id: 221109:OB_RS02270
uniprot id: Q8ET54
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

221109:OB RS06720
gene id: 221109:OB_RS06720
uniprot id: Q8CXJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS11290
gene id: 221109:OB_RS11290
uniprot id: Q8CXA7
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

221109:OB RS00940
gene id: 221109:OB_RS00940
uniprot id: Q8ETU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

221109:OB RS04270
gene id: 221109:OB_RS04270
uniprot id: Q8ES48
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

221109:OB RS13330
gene id: 221109:OB_RS13330
uniprot id: Q8EN84
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

221109:OB RS14550
gene id: 221109:OB_RS14550
uniprot id: Q8EMJ4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

221109:OB RS05880
gene id: 221109:OB_RS05880
uniprot id: Q8CUJ8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

221109:OB RS17485
gene id: 221109:OB_RS17485
uniprot id: Q8EL00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

221109:OB RS12145
gene id: 221109:OB_RS12145
uniprot id: Q8ENW4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

221109:OB RS15270
gene id: 221109:OB_RS15270
uniprot id: Q8EM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

221109:OB RS01440
gene id: 221109:OB_RS01440
uniprot id: Q8ETL8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00860
gene id: 221109:OB_RS00860
uniprot id: Q8ETW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

221109:OB RS01090
gene id: 221109:OB_RS01090
uniprot id: Q8ETS1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

221109:OB RS00885
gene id: 221109:OB_RS00885
uniprot id: Q8ETV8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

221109:OB RS14850
gene id: 221109:OB_RS14850
uniprot id: Q8EME0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

221109:OB RS04785
gene id: 221109:OB_RS04785
uniprot id: Q8CV57
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS10915
gene id: 221109:OB_RS10915
uniprot id: Q8EPI5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

221109:OB RS09625
gene id: 221109:OB_RS09625
uniprot id: Q8EQ50
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

221109:OB RS15880
gene id: 221109:OB_RS15880
uniprot id: Q8ELV0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

221109:OB RS07065
gene id: 221109:OB_RS07065
uniprot id: Q8CXJ6
names: Cofactor
messages: Binds 1 FAD per subunit.

221109:OB RS16380
gene id: 221109:OB_RS16380
uniprot id: Q8CWF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

221109:OB RS05470
gene id: 221109:OB_RS05470
uniprot id: Q8CUT2
names: Similarity
messages: Belongs to the UPF0398 family.

221109:OB RS09115
gene id: 221109:OB_RS09115
uniprot id: Q8EQD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS09380
gene id: 221109:OB_RS09380
uniprot id: Q8CXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. ResA subfamily.
messages: Cell membrane
messages: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.

221109:OB RS05710
gene id: 221109:OB_RS05710
uniprot id: Q8CUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

221109:OB RS07355
gene id: 221109:OB_RS07355
uniprot id: Q8CXJ3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

221109:OB RS15945
gene id: 221109:OB_RS15945
uniprot id: Q8ELT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

221109:OB RS07715
gene id: 221109:OB_RS07715
uniprot id: Q8CXH9
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

221109:OB RS00760
gene id: 221109:OB_RS00760
uniprot id: Q8ETX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

221109:OB RS13385
gene id: 221109:OB_RS13385
uniprot id: Q8EN73
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS00055
gene id: 221109:OB_RS00055
uniprot id: Q8EU79
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

221109:OB RS05450
gene id: 221109:OB_RS05450
uniprot id: Q8CUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

221109:OB RS10450
gene id: 221109:OB_RS10450
uniprot id: Q8EPR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

221109:OB RS10555
gene id: 221109:OB_RS10555
uniprot id: Q8EPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

221109:OB RS12350
gene id: 221109:OB_RS12350
uniprot id: Q8ENS3
names: Cofactor
messages: Can also use Mn(2+) ion.

221109:OB RS00800
gene id: 221109:OB_RS00800
uniprot id: Q8ETX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

221109:OB RS15185
gene id: 221109:OB_RS15185
uniprot id: Q8EM84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

221109:OB RS12055
gene id: 221109:OB_RS12055
uniprot id: Q8ENY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

221109:OB RS15195
gene id: 221109:OB_RS15195
uniprot id: Q8EM82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

221109:OB RS08225
gene id: 221109:OB_RS08225
uniprot id: Q8EQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

221109:OB RS08135
gene id: 221109:OB_RS08135
uniprot id: Q8EQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

221109:OB RS15835
gene id: 221109:OB_RS15835
uniprot id: Q8CX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

221109:OB RS00645
gene id: 221109:OB_RS00645
uniprot id: Q8EU00
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

221109:OB RS11440
gene id: 221109:OB_RS11440
uniprot id: Q8EP89
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

221109:OB RS01945
gene id: 221109:OB_RS01945
uniprot id: Q8ETB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

221109:OB RS17345
gene id: 221109:OB_RS17345
uniprot id: Q8EL27
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS16830
gene id: 221109:OB_RS16830
uniprot id: Q8CX57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

221109:OB RS03315
gene id: 221109:OB_RS03315
uniprot id: Q8ESL0
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS10805
gene id: 221109:OB_RS10805
uniprot id: Q8EPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

221109:OB RS04140
gene id: 221109:OB_RS04140
uniprot id: Q8ES75
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

221109:OB RS07750
gene id: 221109:OB_RS07750
uniprot id: Q8ER36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

221109:OB RS10980
gene id: 221109:OB_RS10980
uniprot id: Q8EPH2
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

221109:OB RS12830
gene id: 221109:OB_RS12830
uniprot id: Q8ENI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

221109:OB RS12495
gene id: 221109:OB_RS12495
uniprot id: Q8ENP5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

221109:OB RS05485
gene id: 221109:OB_RS05485
uniprot id: Q8CUS8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

221109:OB RS08005
gene id: 221109:OB_RS08005
uniprot id: Q8EQY9
names: Similarity
messages: Belongs to the DprA/Smf family.

221109:OB RS17590
gene id: 221109:OB_RS17590
uniprot id: Q8EKX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

221109:OB RS12485
gene id: 221109:OB_RS12485
uniprot id: Q8CWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

221109:OB RS02840
gene id: 221109:OB_RS02840
uniprot id: Q8ESU3
names: Similarity
messages: Belongs to the TrpF family.

221109:OB RS08875
gene id: 221109:OB_RS08875
uniprot id: Q8EQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

221109:OB RS07085
gene id: 221109:OB_RS07085
uniprot id: Q8ERE9
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

221109:OB RS10155
gene id: 221109:OB_RS10155
uniprot id: Q8EPW3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

221109:OB RS11145
gene id: 221109:OB_RS11145
uniprot id: Q8EPE1
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

221109:OB RS09190
gene id: 221109:OB_RS09190
uniprot id: Q8EQB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

221109:OB RS07430
gene id: 221109:OB_RS07430
uniprot id: Q8CXI9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07280
gene id: 221109:OB_RS07280
uniprot id: Q8ERA9
names: Similarity
messages: Belongs to the SCO1/2 family.

221109:OB RS04370
gene id: 221109:OB_RS04370
uniprot id: Q8ES27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. Is involved in a myo-inositol catabolic pathway. Bicarbonate, and not CO2, is the end-product of the enzymatic reaction.
messages: Homotetramer.

221109:OB RS07735
gene id: 221109:OB_RS07735
uniprot id: Q8CXH7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS02685
gene id: 221109:OB_RS02685
uniprot id: Q8ESX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

221109:OB RS10180
gene id: 221109:OB_RS10180
uniprot id: Q8CXC9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

221109:OB RS07880
gene id: 221109:OB_RS07880
uniprot id: Q8ER11
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

221109:OB RS04075
gene id: 221109:OB_RS04075
uniprot id: Q8ES87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

221109:OB RS07850
gene id: 221109:OB_RS07850
uniprot id: Q8ER17
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

221109:OB RS14055
gene id: 221109:OB_RS14055
uniprot id: Q8EMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

221109:OB RS07610
gene id: 221109:OB_RS07610
uniprot id: Q8CZE6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

221109:OB RS10160
gene id: 221109:OB_RS10160
uniprot id: Q8CXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

221109:OB RS12320
gene id: 221109:OB_RS12320
uniprot id: Q8ENS9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

221109:OB RS08395
gene id: 221109:OB_RS08395
uniprot id: Q8EQR8
names: Similarity
messages: Belongs to the CinA family.

221109:OB RS08950
gene id: 221109:OB_RS08950
uniprot id: Q8EQG4
names: Similarity
messages: Belongs to the UPF0346 family.

221109:OB RS07480
gene id: 221109:OB_RS07480
uniprot id: Q8ER73
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS12930
gene id: 221109:OB_RS12930
uniprot id: Q8ENG3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

221109:OB RS16685
gene id: 221109:OB_RS16685
uniprot id: Q8CX59
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

221109:OB RS16055
gene id: 221109:OB_RS16055
uniprot id: Q8ELR9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

221109:OB RS15215
gene id: 221109:OB_RS15215
uniprot id: Q8EM78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

221109:OB RS14675
gene id: 221109:OB_RS14675
uniprot id: Q8EMH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

221109:OB RS10550
gene id: 221109:OB_RS10550
uniprot id: Q8EPP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

221109:OB RS02585
gene id: 221109:OB_RS02585
uniprot id: Q8ESZ1
names: Similarity
messages: Belongs to the ThiD family.

221109:OB RS02665
gene id: 221109:OB_RS02665
uniprot id: Q8ESX7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11125
gene id: 221109:OB_RS11125
uniprot id: Q8EPE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

221109:OB RS05370
gene id: 221109:OB_RS05370
uniprot id: Q8CUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

221109:OB RS05245
gene id: 221109:OB_RS05245
uniprot id: Q8CUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS05335
gene id: 221109:OB_RS05335
uniprot id: Q8CUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS01025
gene id: 221109:OB_RS01025
uniprot id: Q8CXP0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

221109:OB RS08150
gene id: 221109:OB_RS08150
uniprot id: Q8EQW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

221109:OB RS04175
gene id: 221109:OB_RS04175
uniprot id: Q8ES68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS04530
gene id: 221109:OB_RS04530
uniprot id: Q8CVA8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

221109:OB RS10685
gene id: 221109:OB_RS10685
uniprot id: Q8CXB9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

221109:OB RS01370
gene id: 221109:OB_RS01370
uniprot id: Q8CXN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS07030
gene id: 221109:OB_RS07030
uniprot id: Q8ERF9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

221109:OB RS14855
gene id: 221109:OB_RS14855
uniprot id: Q8CX84
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15225
gene id: 221109:OB_RS15225
uniprot id: Q8EM76
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS04095
gene id: 221109:OB_RS04095
uniprot id: Q8ES83
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

221109:OB RS10055
gene id: 221109:OB_RS10055
uniprot id: Q8CXD4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

221109:OB RS05775
gene id: 221109:OB_RS05775
uniprot id: Q8CUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

221109:OB RS00310
gene id: 221109:OB_RS00310
uniprot id: Q8EU33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

221109:OB RS17765
gene id: 221109:OB_RS17765
uniprot id: Q8EKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

221109:OB RS01540
gene id: 221109:OB_RS01540
uniprot id: Q8ETK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS01390
gene id: 221109:OB_RS01390
uniprot id: Q8ETM7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

221109:OB RS06320
gene id: 221109:OB_RS06320
uniprot id: Q8ERU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

221109:OB RS10745
gene id: 221109:OB_RS10745
uniprot id: Q8EPL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

221109:OB RS02895
gene id: 221109:OB_RS02895
uniprot id: Q8EST3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

221109:OB RS05920
gene id: 221109:OB_RS05920
uniprot id: Q8CUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

221109:OB RS15475
gene id: 221109:OB_RS15475
uniprot id: Q8EM26
names: Similarity
messages: Belongs to the OsmC/Ohr family.

221109:OB RS09230
gene id: 221109:OB_RS09230
uniprot id: Q8CXF6
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

221109:OB RS14495
gene id: 221109:OB_RS14495
uniprot id: Q8EMK5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

221109:OB RS12030
gene id: 221109:OB_RS12030
uniprot id: Q8ENY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

221109:OB RS06155
gene id: 221109:OB_RS06155
uniprot id: Q8ERX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

221109:OB RS07700
gene id: 221109:OB_RS07700
uniprot id: Q8ER41
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

221109:OB RS08495
gene id: 221109:OB_RS08495
uniprot id: Q8EQQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS14420
gene id: 221109:OB_RS14420
uniprot id: Q8EMM0
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS05915
gene id: 221109:OB_RS05915
uniprot id: Q8CUI9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07520
gene id: 221109:OB_RS07520
uniprot id: Q8ER66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

221109:OB RS14780
gene id: 221109:OB_RS14780
uniprot id: Q8EMF3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

221109:OB RS06215
gene id: 221109:OB_RS06215
uniprot id: Q8ERW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

221109:OB RS04630
gene id: 221109:OB_RS04630
uniprot id: Q8CV88
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

221109:OB RS14680
gene id: 221109:OB_RS14680
uniprot id: Q8EMH0
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS14450
gene id: 221109:OB_RS14450
uniprot id: Q8EML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS15325
gene id: 221109:OB_RS15325
uniprot id: Q8CX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

221109:OB RS00040
gene id: 221109:OB_RS00040
uniprot id: Q8EU82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

221109:OB RS03850
gene id: 221109:OB_RS03850
uniprot id: Q8ESD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS13960
gene id: 221109:OB_RS13960
uniprot id: Q8EMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

221109:OB RS10900
gene id: 221109:OB_RS10900
uniprot id: Q8EPI6
names: Similarity
messages: Belongs to the thioredoxin family.

221109:OB RS16430
gene id: 221109:OB_RS16430
uniprot id: Q8ELK2
names: Similarity
messages: Belongs to the CdaR family.

221109:OB RS09920
gene id: 221109:OB_RS09920
uniprot id: Q8EQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

221109:OB RS13570
gene id: 221109:OB_RS13570
uniprot id: Q8EN39
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

221109:OB RS02965
gene id: 221109:OB_RS02965
uniprot id: Q8ESS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

221109:OB RS16640
gene id: 221109:OB_RS16640
uniprot id: Q8ELG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

221109:OB RS16575
gene id: 221109:OB_RS16575
uniprot id: Q8ELH4
names: Similarity
messages: Belongs to the acylphosphatase family.

221109:OB RS07710
gene id: 221109:OB_RS07710
uniprot id: Q8ER39
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

221109:OB RS05080
gene id: 221109:OB_RS05080
uniprot id: Q8CV11
names: Similarity
messages: Belongs to the MQO family.

221109:OB RS04130
gene id: 221109:OB_RS04130
uniprot id: Q8ES77
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

221109:OB RS07465
gene id: 221109:OB_RS07465
uniprot id: Q8ER76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

221109:OB RS07675
gene id: 221109:OB_RS07675
uniprot id: Q8ER45
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

221109:OB RS09105
gene id: 221109:OB_RS09105
uniprot id: Q8EQD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

221109:OB RS04045
gene id: 221109:OB_RS04045
uniprot id: Q8CXK7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

221109:OB RS15750
gene id: 221109:OB_RS15750
uniprot id: Q8ELX5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

221109:OB RS02730
gene id: 221109:OB_RS02730
uniprot id: Q8ESW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS07425
gene id: 221109:OB_RS07425
uniprot id: Q8ER84
names: Similarity
messages: Belongs to the UPF0358 family.

221109:OB RS00410
gene id: 221109:OB_RS00410
uniprot id: Q8CXP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

221109:OB RS10230
gene id: 221109:OB_RS10230
uniprot id: Q8EPV1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

221109:OB RS12060
gene id: 221109:OB_RS12060
uniprot id: Q8ENX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

221109:OB RS00015
gene id: 221109:OB_RS00015
uniprot id: Q8EU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

221109:OB RS11825
gene id: 221109:OB_RS11825
uniprot id: Q8EP19
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05735
gene id: 221109:OB_RS05735
uniprot id: Q8CUM7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS07605
gene id: 221109:OB_RS07605
uniprot id: Q8CXI6
names: Similarity
messages: Belongs to the transpeptidase family.

221109:OB RS00190
gene id: 221109:OB_RS00190
uniprot id: Q8EU53
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

221109:OB RS02850
gene id: 221109:OB_RS02850
uniprot id: Q8ESU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

221109:OB RS16585
gene id: 221109:OB_RS16585
uniprot id: Q8ELH2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

221109:OB RS10690
gene id: 221109:OB_RS10690
uniprot id: Q8CXB8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

221109:OB RS14730
gene id: 221109:OB_RS14730
uniprot id: Q8EMG3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

221109:OB RS02390
gene id: 221109:OB_RS02390
uniprot id: Q8ET30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

221109:OB RS09320
gene id: 221109:OB_RS09320
uniprot id: Q8EQ98
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

221109:OB RS09040
gene id: 221109:OB_RS09040
uniprot id: Q8CXF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

221109:OB RS15790
gene id: 221109:OB_RS15790
uniprot id: Q8ELW7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

221109:OB RS08255
gene id: 221109:OB_RS08255
uniprot id: Q8EQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

221109:OB RS13170
gene id: 221109:OB_RS13170
uniprot id: Q8ENB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS09770
gene id: 221109:OB_RS09770
uniprot id: Q8EQ23
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

221109:OB RS12640
gene id: 221109:OB_RS12640
uniprot id: Q8ENM0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

221109:OB RS13775
gene id: 221109:OB_RS13775
uniprot id: Q8EMZ7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

221109:OB RS01380
gene id: 221109:OB_RS01380
uniprot id: Q8ETM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

221109:OB RS12975
gene id: 221109:OB_RS12975
uniprot id: Q8ENF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LytR/CpsA/Psr (LCP) family.
messages: Cell membrane
messages: May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).

221109:OB RS17715
gene id: 221109:OB_RS17715
uniprot id: Q8EKV4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

221109:OB RS14815
gene id: 221109:OB_RS14815
uniprot id: Q8EME7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS17585
gene id: 221109:OB_RS17585
uniprot id: Q8EKY0
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS15250
gene id: 221109:OB_RS15250
uniprot id: Q8EM71
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

221109:OB RS15310
gene id: 221109:OB_RS15310
uniprot id: Q8EM57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS03510
gene id: 221109:OB_RS03510
uniprot id: Q8ESJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

221109:OB RS13700
gene id: 221109:OB_RS13700
uniprot id: Q8EN13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

221109:OB RS04215
gene id: 221109:OB_RS04215
uniprot id: Q8ES60
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

221109:OB RS07190
gene id: 221109:OB_RS07190
uniprot id: Q8ERC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

221109:OB RS17545
gene id: 221109:OB_RS17545
uniprot id: Q8EKY8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

221109:OB RS12575
gene id: 221109:OB_RS12575
uniprot id: Q8ENN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS08310
gene id: 221109:OB_RS08310
uniprot id: Q8EQT5
names: Similarity
messages: Belongs to the peptidase M16 family.

221109:OB RS11190
gene id: 221109:OB_RS11190
uniprot id: Q8CXA9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

221109:OB RS09875
gene id: 221109:OB_RS09875
uniprot id: Q8EQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

221109:OB RS08595
gene id: 221109:OB_RS08595
uniprot id: Q8EQN3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

221109:OB RS02375
gene id: 221109:OB_RS02375
uniprot id: Q8ET33
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

221109:OB RS15245
gene id: 221109:OB_RS15245
uniprot id: Q8EM72
names: Similarity
messages: Belongs to the UPF0340 family.

221109:OB RS06150
gene id: 221109:OB_RS06150
uniprot id: Q8ERY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS13220
gene id: 221109:OB_RS13220
uniprot id: Q8ENA7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

221109:OB RS10205
gene id: 221109:OB_RS10205
uniprot id: Q8EPV6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

221109:OB RS16125
gene id: 221109:OB_RS16125
uniprot id: Q8ELQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

221109:OB RS06730
gene id: 221109:OB_RS06730
uniprot id: Q8ERL9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

221109:OB RS00765
gene id: 221109:OB_RS00765
uniprot id: Q8ETX8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

221109:OB RS17580
gene id: 221109:OB_RS17580
uniprot id: Q8EKY1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS17285
gene id: 221109:OB_RS17285
uniprot id: Q8EL40
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

221109:OB RS09680
gene id: 221109:OB_RS09680
uniprot id: Q8EQ41
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11795
gene id: 221109:OB_RS11795
uniprot id: Q8EP25
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

221109:OB RS16985
gene id: 221109:OB_RS16985
uniprot id: Q8EL98
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

221109:OB RS16590
gene id: 221109:OB_RS16590
uniprot id: Q8ELH1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05590
gene id: 221109:OB_RS05590
uniprot id: Q8CUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

221109:OB RS10630
gene id: 221109:OB_RS10630
uniprot id: Q8CXC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

221109:OB RS10145
gene id: 221109:OB_RS10145
uniprot id: Q8EPW4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

221109:OB RS10425
gene id: 221109:OB_RS10425
uniprot id: Q8EPR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS10340
gene id: 221109:OB_RS10340
uniprot id: Q8EPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

221109:OB RS14155
gene id: 221109:OB_RS14155
uniprot id: Q8EMS0
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

221109:OB RS16170
gene id: 221109:OB_RS16170
uniprot id: Q8CX66
names: Similarity
messages: Belongs to the serpin family.

221109:OB RS08115
gene id: 221109:OB_RS08115
uniprot id: Q8EQX1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

221109:OB RS01920
gene id: 221109:OB_RS01920
uniprot id: Q8ETC2
names: Similarity
messages: Belongs to the LOG family.

221109:OB RS13200
gene id: 221109:OB_RS13200
uniprot id: Q8ENB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

221109:OB RS01785
gene id: 221109:OB_RS01785
uniprot id: Q8ETF2
names: Subunit
messages: Homodimer.

221109:OB RS13955
gene id: 221109:OB_RS13955
uniprot id: Q8EMV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

221109:OB RS04035
gene id: 221109:OB_RS04035
uniprot id: Q8ES94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

221109:OB RS09475
gene id: 221109:OB_RS09475
uniprot id: Q8EQ71
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

221109:OB RS17350
gene id: 221109:OB_RS17350
uniprot id: Q8EL26
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

221109:OB RS04010
gene id: 221109:OB_RS04010
uniprot id: Q8ES99
names: Similarity
messages: Belongs to the SAICAR synthetase family.

221109:OB RS17970
gene id: 221109:OB_RS17970
uniprot id: Q8EN05
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

221109:OB RS08300
gene id: 221109:OB_RS08300
uniprot id: Q8EQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

221109:OB RS01690
gene id: 221109:OB_RS01690
uniprot id: Q8ETH0
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.

221109:OB RS07940
gene id: 221109:OB_RS07940
uniprot id: Q8ER01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

221109:OB RS07310
gene id: 221109:OB_RS07310
uniprot id: Q8ERA3
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

221109:OB RS06690
gene id: 221109:OB_RS06690
uniprot id: Q8ERM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

221109:OB RS02625
gene id: 221109:OB_RS02625
uniprot id: Q8ESY3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

221109:OB RS09205
gene id: 221109:OB_RS09205
uniprot id: Q8CXF8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

221109:OB RS14980
gene id: 221109:OB_RS14980
uniprot id: Q8CX79
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12695
gene id: 221109:OB_RS12695
uniprot id: Q8ENL0
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

221109:OB RS15950
gene id: 221109:OB_RS15950
uniprot id: Q8ELT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

221109:OB RS06340
gene id: 221109:OB_RS06340
uniprot id: Q8ERU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

221109:OB RS14685
gene id: 221109:OB_RS14685
uniprot id: Q8CX89
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

221109:OB RS00035
gene id: 221109:OB_RS00035
uniprot id: Q8EU83
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

221109:OB RS10670
gene id: 221109:OB_RS10670
uniprot id: Q8EPM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS08330
gene id: 221109:OB_RS08330
uniprot id: Q8EQT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS10135
gene id: 221109:OB_RS10135
uniprot id: Q8EPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

221109:OB RS13745
gene id: 221109:OB_RS13745
uniprot id: Q8EN03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

221109:OB RS07925
gene id: 221109:OB_RS07925
uniprot id: Q8CXH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

221109:OB RS17630
gene id: 221109:OB_RS17630
uniprot id: Q8EKX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

221109:OB RS03995
gene id: 221109:OB_RS03995
uniprot id: Q8ESA2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

221109:OB RS10295
gene id: 221109:OB_RS10295
uniprot id: Q8CZE4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

221109:OB RS17300
gene id: 221109:OB_RS17300
uniprot id: Q8EL37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

221109:OB RS12825
gene id: 221109:OB_RS12825
uniprot id: Q8ENI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacillales FliT family.
messages: Homodimer.
messages: May act as an export chaperone for the filament capping protein FliD.
messages: cytosol

221109:OB RS00840
gene id: 221109:OB_RS00840
uniprot id: Q8ETW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

221109:OB RS02110
gene id: 221109:OB_RS02110
uniprot id: Q8ET85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

221109:OB RS14785
gene id: 221109:OB_RS14785
uniprot id: Q8CX86
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

221109:OB RS08455
gene id: 221109:OB_RS08455
uniprot id: Q8EQQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

221109:OB RS04505
gene id: 221109:OB_RS04505
uniprot id: Q8ES01
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

221109:OB RS10560
gene id: 221109:OB_RS10560
uniprot id: Q8EPP1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

221109:OB RS12770
gene id: 221109:OB_RS12770
uniprot id: Q8ENJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

221109:OB RS06460
gene id: 221109:OB_RS06460
uniprot id: Q8ERR9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00305
gene id: 221109:OB_RS00305
uniprot id: Q8EU34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

221109:OB RS07740
gene id: 221109:OB_RS07740
uniprot id: Q8CXH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

221109:OB RS03280
gene id: 221109:OB_RS03280
uniprot id: Q8ESL6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

221109:OB RS02910
gene id: 221109:OB_RS02910
uniprot id: Q8EST0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

221109:OB RS07785
gene id: 221109:OB_RS07785
uniprot id: Q8ER29
names: Similarity
messages: Belongs to the RemA family.

221109:OB RS15540
gene id: 221109:OB_RS15540
uniprot id: Q8EM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

221109:OB RS17200
gene id: 221109:OB_RS17200
uniprot id: Q8EL56
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

221109:OB RS01980
gene id: 221109:OB_RS01980
uniprot id: Q8ETB0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

221109:OB RS14115
gene id: 221109:OB_RS14115
uniprot id: Q8EMS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

221109:OB RS10415
gene id: 221109:OB_RS10415
uniprot id: Q8EPR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS05805
gene id: 221109:OB_RS05805
uniprot id: Q8CUL3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

221109:OB RS00260
gene id: 221109:OB_RS00260
uniprot id: P59155
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

221109:OB RS15145
gene id: 221109:OB_RS15145
uniprot id: Q8EM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

221109:OB RS14805
gene id: 221109:OB_RS14805
uniprot id: Q8EME9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

221109:OB RS13880
gene id: 221109:OB_RS13880
uniprot id: Q8EMX5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

221109:OB RS08970
gene id: 221109:OB_RS08970
uniprot id: Q8EQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS09465
gene id: 221109:OB_RS09465
uniprot id: Q8EQ73
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

221109:OB RS16375
gene id: 221109:OB_RS16375
uniprot id: Q8ELL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

221109:OB RS09135
gene id: 221109:OB_RS09135
uniprot id: Q8EQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Component of the menaquinol:cytochrome c reductase complex.
messages: Membrane
messages: The main subunits of the menaquinol:cytochrome c complex are a Rieske-type iron-sulfur protein (QcrA), a cytochrome b (QcrB) and a cytochrome c (QcrC).

221109:OB RS08020
gene id: 221109:OB_RS08020
uniprot id: Q7ZAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

221109:OB RS12980
gene id: 221109:OB_RS12980
uniprot id: Q8ENF2
names: Similarity
messages: Belongs to the transpeptidase family.

221109:OB RS07875
gene id: 221109:OB_RS07875
uniprot id: Q8ER12
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

221109:OB RS11195
gene id: 221109:OB_RS11195
uniprot id: Q8CXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

221109:OB RS09500
gene id: 221109:OB_RS09500
uniprot id: Q7ZAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

221109:OB RS09385
gene id: 221109:OB_RS09385
uniprot id: Q8EQ87
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

221109:OB RS08185
gene id: 221109:OB_RS08185
uniprot id: Q8EQV8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

221109:OB RS07125
gene id: 221109:OB_RS07125
uniprot id: Q8ERE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.
messages: Thr-13 is present instead of the conserved Cys which is potentially a redox-active site.

221109:OB RS07600
gene id: 221109:OB_RS07600
uniprot id: Q8CXI7
names: Similarity
messages: Belongs to the transpeptidase family.

221109:OB RS15980
gene id: 221109:OB_RS15980
uniprot id: Q8ELT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

221109:OB RS09460
gene id: 221109:OB_RS09460
uniprot id: Q8EQ74
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

221109:OB RS09970
gene id: 221109:OB_RS09970
uniprot id: Q8EPZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS13535
gene id: 221109:OB_RS13535
uniprot id: Q8EN44
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS09580
gene id: 221109:OB_RS09580
uniprot id: Q8EQ52
names: Similarity
messages: Belongs to the bacilliredoxin family.

221109:OB RS05725
gene id: 221109:OB_RS05725
uniprot id: Q8CUM9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

221109:OB RS00735
gene id: 221109:OB_RS00735
uniprot id: Q8ETY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

221109:OB RS02045
gene id: 221109:OB_RS02045
uniprot id: Q8ET97
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07895
gene id: 221109:OB_RS07895
uniprot id: Q8ER08
names: Similarity
messages: Belongs to the fabD family.

221109:OB RS06370
gene id: 221109:OB_RS06370
uniprot id: Q8ERT6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

221109:OB RS06050
gene id: 221109:OB_RS06050
uniprot id: Q8CUG1
names: Function
names: Similarity
messages: Belongs to the YhaM family.
messages: Shows a 3'-5' exoribonuclease activity.

221109:OB RS02660
gene id: 221109:OB_RS02660
uniprot id: Q8CXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

221109:OB RS14820
gene id: 221109:OB_RS14820
uniprot id: Q8CX85
names: Similarity
messages: Belongs to the peptidase C40 family.

221109:OB RS13265
gene id: 221109:OB_RS13265
uniprot id: Q8EN97
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

221109:OB RS12280
gene id: 221109:OB_RS12280
uniprot id: Q8ENT8
names: Similarity
messages: Belongs to the ArsC family.

221109:OB RS03370
gene id: 221109:OB_RS03370
uniprot id: Q8CXL7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

221109:OB RS16945
gene id: 221109:OB_RS16945
uniprot id: Q8ELA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

221109:OB RS16435
gene id: 221109:OB_RS16435
uniprot id: Q8CX61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle during sporulation (By similarity).
messages: Cytoplasm
messages: Homohexamer.

221109:OB RS06385
gene id: 221109:OB_RS06385
uniprot id: Q8ERT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

221109:OB RS12415
gene id: 221109:OB_RS12415
uniprot id: Q8ENR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

221109:OB RS11970
gene id: 221109:OB_RS11970
uniprot id: Q8CWF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

221109:OB RS12850
gene id: 221109:OB_RS12850
uniprot id: Q8ENH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

221109:OB RS01705
gene id: 221109:OB_RS01705
uniprot id: Q8ETG8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS10100
gene id: 221109:OB_RS10100
uniprot id: Q8EPX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Membrane raft

221109:OB RS17190
gene id: 221109:OB_RS17190
uniprot id: Q8EL58
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12520
gene id: 221109:OB_RS12520
uniprot id: Q8CX99
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

221109:OB RS11760
gene id: 221109:OB_RS11760
uniprot id: Q8EP32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

221109:OB RS13650
gene id: 221109:OB_RS13650
uniprot id: Q8EN23
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS10645
gene id: 221109:OB_RS10645
uniprot id: Q8EPM8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15365
gene id: 221109:OB_RS15365
uniprot id: Q8EM48
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

221109:OB RS14165
gene id: 221109:OB_RS14165
uniprot id: Q8EMR8
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

221109:OB RS07905
gene id: 221109:OB_RS07905
uniprot id: Q8ER06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

221109:OB RS01645
gene id: 221109:OB_RS01645
uniprot id: Q8ETH9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

221109:OB RS14810
gene id: 221109:OB_RS14810
uniprot id: Q8EME8
names: Similarity
messages: Belongs to the CpsD/CapB family.

221109:OB RS02925
gene id: 221109:OB_RS02925
uniprot id: Q8ESS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS14260
gene id: 221109:OB_RS14260
uniprot id: Q8EMQ0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

221109:OB RS09015
gene id: 221109:OB_RS09015
uniprot id: Q8EQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

221109:OB RS15220
gene id: 221109:OB_RS15220
uniprot id: Q8EM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

221109:OB RS13410
gene id: 221109:OB_RS13410
uniprot id: Q8EN68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS12600
gene id: 221109:OB_RS12600
uniprot id: Q8ENM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

221109:OB RS14535
gene id: 221109:OB_RS14535
uniprot id: Q8EMJ7
names: Similarity
messages: Belongs to the DapA family.

221109:OB RS10800
gene id: 221109:OB_RS10800
uniprot id: Q8EPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS06725
gene id: 221109:OB_RS06725
uniprot id: Q8ERM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

221109:OB RS10930
gene id: 221109:OB_RS10930
uniprot id: Q8EPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

221109:OB RS12135
gene id: 221109:OB_RS12135
uniprot id: Q8ENW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

221109:OB RS10025
gene id: 221109:OB_RS10025
uniprot id: Q8EPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

221109:OB RS14975
gene id: 221109:OB_RS14975
uniprot id: Q8EMC2
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS14065
gene id: 221109:OB_RS14065
uniprot id: Q8EMT7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00785
gene id: 221109:OB_RS00785
uniprot id: Q8ETX5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

221109:OB RS06440
gene id: 221109:OB_RS06440
uniprot id: Q8ERS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

221109:OB RS07625
gene id: 221109:OB_RS07625
uniprot id: Q8ER50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

221109:OB RS14510
gene id: 221109:OB_RS14510
uniprot id: Q8EMK2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS14375
gene id: 221109:OB_RS14375
uniprot id: Q8EMM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

221109:OB RS08745
gene id: 221109:OB_RS08745
uniprot id: Q8EQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

221109:OB RS10345
gene id: 221109:OB_RS10345
uniprot id: Q8EPT0
names: Similarity
messages: Belongs to the UPF0297 family.

221109:OB RS14335
gene id: 221109:OB_RS14335
uniprot id: Q8EMN6
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

221109:OB RS12360
gene id: 221109:OB_RS12360
uniprot id: Q8ENS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0421 family.
messages: Cell membrane

221109:OB RS08985
gene id: 221109:OB_RS08985
uniprot id: Q8EQF7
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS00825
gene id: 221109:OB_RS00825
uniprot id: Q8ETW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

221109:OB RS15420
gene id: 221109:OB_RS15420
uniprot id: Q8EM37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

221109:OB RS10965
gene id: 221109:OB_RS10965
uniprot id: Q8EPH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

221109:OB RS03010
gene id: 221109:OB_RS03010
uniprot id: Q8ESR3
names: Subcellular Location Annotation
messages: Cell membrane

221109:OB RS06160
gene id: 221109:OB_RS06160
uniprot id: Q8ERX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

221109:OB RS07685
gene id: 221109:OB_RS07685
uniprot id: Q8ER43
names: Similarity
messages: Belongs to the YggT family.

221109:OB RS10015
gene id: 221109:OB_RS10015
uniprot id: Q8EPY8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

221109:OB RS04660
gene id: 221109:OB_RS04660
uniprot id: Q8CV82
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05350
gene id: 221109:OB_RS05350
uniprot id: Q8CUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS15840
gene id: 221109:OB_RS15840
uniprot id: Q8ELV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

221109:OB RS17470
gene id: 221109:OB_RS17470
uniprot id: Q8EL03
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

221109:OB RS03230
gene id: 221109:OB_RS03230
uniprot id: Q8ESM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

221109:OB RS00815
gene id: 221109:OB_RS00815
uniprot id: Q8ETW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

221109:OB RS09975
gene id: 221109:OB_RS09975
uniprot id: Q8EPZ6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11165
gene id: 221109:OB_RS11165
uniprot id: Q8EPD7
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

221109:OB RS08170
gene id: 221109:OB_RS08170
uniprot id: Q8EQW0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

221109:OB RS15515
gene id: 221109:OB_RS15515
uniprot id: Q8EM19
names: Similarity
messages: Belongs to the peptidase M29 family.

221109:OB RS07995
gene id: 221109:OB_RS07995
uniprot id: Q8EQZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

221109:OB RS15370
gene id: 221109:OB_RS15370
uniprot id: Q8EM47
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

221109:OB RS14775
gene id: 221109:OB_RS14775
uniprot id: Q8EMF4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

221109:OB RS08565
gene id: 221109:OB_RS08565
uniprot id: Q8EQN9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

221109:OB RS13205
gene id: 221109:OB_RS13205
uniprot id: Q8ENB1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

221109:OB RS08485
gene id: 221109:OB_RS08485
uniprot id: Q8EQQ3
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
messages: Phosphorylated by LytS.

221109:OB RS08235
gene id: 221109:OB_RS08235
uniprot id: Q8EQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

221109:OB RS00640
gene id: 221109:OB_RS00640
uniprot id: Q8EU02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

221109:OB RS09165
gene id: 221109:OB_RS09165
uniprot id: Q8EQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

221109:OB RS00790
gene id: 221109:OB_RS00790
uniprot id: Q8ETX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

221109:OB RS11665
gene id: 221109:OB_RS11665
uniprot id: Q8EP49
names: Similarity
messages: Belongs to the PrpD family.

221109:OB RS16625
gene id: 221109:OB_RS16625
uniprot id: Q8ELG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

221109:OB RS02700
gene id: 221109:OB_RS02700
uniprot id: Q8ESX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

221109:OB RS08040
gene id: 221109:OB_RS08040
uniprot id: Q8EQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

221109:OB RS04180
gene id: 221109:OB_RS04180
uniprot id: Q8ES67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS09250
gene id: 221109:OB_RS09250
uniprot id: Q8EQA8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

221109:OB RS09170
gene id: 221109:OB_RS09170
uniprot id: Q8EQC0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

221109:OB RS07560
gene id: 221109:OB_RS07560
uniprot id: Q8ER59
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

221109:OB RS09570
gene id: 221109:OB_RS09570
uniprot id: Q8EQ54
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

221109:OB RS12585
gene id: 221109:OB_RS12585
uniprot id: Q8ENM9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS00890
gene id: 221109:OB_RS00890
uniprot id: Q8ETV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

221109:OB RS08110
gene id: 221109:OB_RS08110
uniprot id: Q8EQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

221109:OB RS00910
gene id: 221109:OB_RS00910
uniprot id: Q8ETV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

221109:OB RS15205
gene id: 221109:OB_RS15205
uniprot id: Q8EM80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

221109:OB RS10200
gene id: 221109:OB_RS10200
uniprot id: Q8EPV7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08245
gene id: 221109:OB_RS08245
uniprot id: Q8EQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

221109:OB RS02275
gene id: 221109:OB_RS02275
uniprot id: Q8ET53
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

221109:OB RS15030
gene id: 221109:OB_RS15030
uniprot id: Q8EMB3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS09490
gene id: 221109:OB_RS09490
uniprot id: Q8EQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

221109:OB RS17600
gene id: 221109:OB_RS17600
uniprot id: Q8EKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS02640
gene id: 221109:OB_RS02640
uniprot id: Q8ESY1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS05605
gene id: 221109:OB_RS05605
uniprot id: Q8CUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

221109:OB RS13030
gene id: 221109:OB_RS13030
uniprot id: Q8ENE3
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12925
gene id: 221109:OB_RS12925
uniprot id: Q8ENG4
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS13335
gene id: 221109:OB_RS13335
uniprot id: Q8EN83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

221109:OB RS08025
gene id: 221109:OB_RS08025
uniprot id: Q8CXH2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

221109:OB RS02565
gene id: 221109:OB_RS02565
uniprot id: Q8ESZ5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07155
gene id: 221109:OB_RS07155
uniprot id: Q8ERD5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

221109:OB RS15925
gene id: 221109:OB_RS15925
uniprot id: Q8ELU2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

221109:OB RS15660
gene id: 221109:OB_RS15660
uniprot id: Q8ELZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

221109:OB RS10165
gene id: 221109:OB_RS10165
uniprot id: Q8CXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

221109:OB RS04390
gene id: 221109:OB_RS04390
uniprot id: Q8ES23
names: Similarity
messages: Belongs to the AHA1 family.

221109:OB RS00225
gene id: 221109:OB_RS00225
uniprot id: Q8EU46
names: Similarity
messages: Belongs to the UPF0213 family.

221109:OB RS00060
gene id: 221109:OB_RS00060
uniprot id: Q8EU78
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

221109:OB RS05865
gene id: 221109:OB_RS05865
uniprot id: Q8CUK1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

221109:OB RS07930
gene id: 221109:OB_RS07930
uniprot id: Q8ER03
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

221109:OB RS15025
gene id: 221109:OB_RS15025
uniprot id: Q8EMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS13350
gene id: 221109:OB_RS13350
uniprot id: Q8EN80
names: Similarity
messages: Belongs to the YciI family.

221109:OB RS16365
gene id: 221109:OB_RS16365
uniprot id: Q8ELL3
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

221109:OB RS14310
gene id: 221109:OB_RS14310
uniprot id: Q8CX91
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS08270
gene id: 221109:OB_RS08270
uniprot id: Q8EQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

221109:OB RS01350
gene id: 221109:OB_RS01350
uniprot id: Q8ETN4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

221109:OB RS07955
gene id: 221109:OB_RS07955
uniprot id: Q8EQZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

221109:OB RS08750
gene id: 221109:OB_RS08750
uniprot id: Q8EQK3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS11550
gene id: 221109:OB_RS11550
uniprot id: Q8EP70
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS11930
gene id: 221109:OB_RS11930
uniprot id: Q8EP00
names: Similarity
messages: Belongs to the Nudix hydrolase family.

221109:OB RS15055
gene id: 221109:OB_RS15055
uniprot id: Q8EMA8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

221109:OB RS10375
gene id: 221109:OB_RS10375
uniprot id: Q8CXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

221109:OB RS03140
gene id: 221109:OB_RS03140
uniprot id: Q8ESP1
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS00835
gene id: 221109:OB_RS00835
uniprot id: Q8ETW6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

221109:OB RS14925
gene id: 221109:OB_RS14925
uniprot id: Q8EMC9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS13615
gene id: 221109:OB_RS13615
uniprot id: Q8EN30
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS02075
gene id: 221109:OB_RS02075
uniprot id: Q8ET92
names: Function
names: Similarity
messages: Belongs to the LutA/YkgE family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

221109:OB RS16460
gene id: 221109:OB_RS16460
uniprot id: Q8ELJ7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

221109:OB RS01410
gene id: 221109:OB_RS01410
uniprot id: Q8ETM4
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS15295
gene id: 221109:OB_RS15295
uniprot id: Q8EM60
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

221109:OB RS00865
gene id: 221109:OB_RS00865
uniprot id: Q8ETW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

221109:OB RS13425
gene id: 221109:OB_RS13425
uniprot id: Q8EN65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

221109:OB RS04185
gene id: 221109:OB_RS04185
uniprot id: Q8ES66
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS04745
gene id: 221109:OB_RS04745
uniprot id: Q8CV65
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

221109:OB RS12805
gene id: 221109:OB_RS12805
uniprot id: Q8ENI9
names: PTM
messages: Binds 1 heme c group covalently per subunit.

221109:OB RS10260
gene id: 221109:OB_RS10260
uniprot id: Q8EPU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

221109:OB RS03600
gene id: 221109:OB_RS03600
uniprot id: Q8CXL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

221109:OB RS02835
gene id: 221109:OB_RS02835
uniprot id: Q8ESU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

221109:OB RS08285
gene id: 221109:OB_RS08285
uniprot id: Q8CXG9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

221109:OB RS15915
gene id: 221109:OB_RS15915
uniprot id: Q8ELU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS07615
gene id: 221109:OB_RS07615
uniprot id: Q8CZE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

221109:OB RS09100
gene id: 221109:OB_RS09100
uniprot id: Q8EQD4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

221109:OB RS14965
gene id: 221109:OB_RS14965
uniprot id: Q8EMC3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

221109:OB RS06120
gene id: 221109:OB_RS06120
uniprot id: Q8ERY5
names: Subcellular Location Annotation
messages: Cell membrane

221109:OB RS06390
gene id: 221109:OB_RS06390
uniprot id: Q8ERT2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

221109:OB RS12435
gene id: 221109:OB_RS12435
uniprot id: Q8ENQ7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

221109:OB RS02225
gene id: 221109:OB_RS02225
uniprot id: Q8ET62
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07550
gene id: 221109:OB_RS07550
uniprot id: Q8ER61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

221109:OB RS09050
gene id: 221109:OB_RS09050
uniprot id: Q8EQE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

221109:OB RS07970
gene id: 221109:OB_RS07970
uniprot id: Q8EQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

221109:OB RS14890
gene id: 221109:OB_RS14890
uniprot id: Q8EMD4
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS07960
gene id: 221109:OB_RS07960
uniprot id: Q8CXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

221109:OB RS00215
gene id: 221109:OB_RS00215
uniprot id: Q8EU48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

221109:OB RS10070
gene id: 221109:OB_RS10070
uniprot id: Q8EPX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

221109:OB RS04815
gene id: 221109:OB_RS04815
uniprot id: Q8CV51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0295 family.
messages: Cell membrane

221109:OB RS10335
gene id: 221109:OB_RS10335
uniprot id: Q8EPT2
names: Similarity
messages: Belongs to the UPF0473 family.

221109:OB RS12775
gene id: 221109:OB_RS12775
uniprot id: Q8ENJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

221109:OB RS08420
gene id: 221109:OB_RS08420
uniprot id: Q8EQR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

221109:OB RS11285
gene id: 221109:OB_RS11285
uniprot id: Q8EPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

221109:OB RS07475
gene id: 221109:OB_RS07475
uniprot id: Q8ER74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

221109:OB RS00905
gene id: 221109:OB_RS00905
uniprot id: Q8CXP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

221109:OB RS17795
gene id: 221109:OB_RS17795
uniprot id: Q8EKU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

221109:OB RS02160
gene id: 221109:OB_RS02160
uniprot id: Q8ET75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

221109:OB RS09275
gene id: 221109:OB_RS09275
uniprot id: Q8CXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

221109:OB RS02035
gene id: 221109:OB_RS02035
uniprot id: Q8ET99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

221109:OB RS00425
gene id: 221109:OB_RS00425
uniprot id: Q8EU15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS13445
gene id: 221109:OB_RS13445
uniprot id: Q8EN61
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

221109:OB RS15755
gene id: 221109:OB_RS15755
uniprot id: Q8ELX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

221109:OB RS13750
gene id: 221109:OB_RS13750
uniprot id: Q8EN02
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS09080
gene id: 221109:OB_RS09080
uniprot id: Q8EQD8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

221109:OB RS07620
gene id: 221109:OB_RS07620
uniprot id: Q8ER51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

221109:OB RS02335
gene id: 221109:OB_RS02335
uniprot id: Q8CXN3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

221109:OB RS10130
gene id: 221109:OB_RS10130
uniprot id: Q8EPW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

221109:OB RS16105
gene id: 221109:OB_RS16105
uniprot id: Q8ELR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

221109:OB RS16705
gene id: 221109:OB_RS16705
uniprot id: Q8ELF0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

221109:OB RS00420
gene id: 221109:OB_RS00420
uniprot id: Q8EU16
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

221109:OB RS05870
gene id: 221109:OB_RS05870
uniprot id: Q8CUK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

221109:OB RS02815
gene id: 221109:OB_RS02815
uniprot id: Q8ESU8
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

221109:OB RS05445
gene id: 221109:OB_RS05445
uniprot id: Q8CUT7
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspP family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

221109:OB RS13610
gene id: 221109:OB_RS13610
uniprot id: Q8EN31
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

221109:OB RS08030
gene id: 221109:OB_RS08030
uniprot id: Q8CXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

221109:OB RS03150
gene id: 221109:OB_RS03150
uniprot id: Q8CXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

221109:OB RS04150
gene id: 221109:OB_RS04150
uniprot id: Q8ES73
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS04605
gene id: 221109:OB_RS04605
uniprot id: Q8CV93
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS16020
gene id: 221109:OB_RS16020
uniprot id: Q8ELS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

221109:OB RS01575
gene id: 221109:OB_RS01575
uniprot id: Q8ETJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS05320
gene id: 221109:OB_RS05320
uniprot id: Q8CUW3
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11070
gene id: 221109:OB_RS11070
uniprot id: Q8EPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

221109:OB RS16405
gene id: 221109:OB_RS16405
uniprot id: Q8ELK7
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS07835
gene id: 221109:OB_RS07835
uniprot id: Q8ER20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

221109:OB RS15150
gene id: 221109:OB_RS15150
uniprot id: Q8EM90
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS04025
gene id: 221109:OB_RS04025
uniprot id: Q8ES96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

221109:OB RS06890
gene id: 221109:OB_RS06890
uniprot id: Q8ERI6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08725
gene id: 221109:OB_RS08725
uniprot id: Q8EQK8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS09700
gene id: 221109:OB_RS09700
uniprot id: Q8EQ37
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

221109:OB RS07635
gene id: 221109:OB_RS07635
uniprot id: Q8CXI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

221109:OB RS09810
gene id: 221109:OB_RS09810
uniprot id: Q8EQ18
names: Similarity
messages: Belongs to the GSP E family.

221109:OB RS02245
gene id: 221109:OB_RS02245
uniprot id: Q8ET58
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

221109:OB RS04100
gene id: 221109:OB_RS04100
uniprot id: Q8CXK6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

221109:OB RS09815
gene id: 221109:OB_RS09815
uniprot id: Q8CXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

221109:OB RS09690
gene id: 221109:OB_RS09690
uniprot id: Q8EQ39
names: Similarity
messages: Belongs to the asp23 family.

221109:OB RS10185
gene id: 221109:OB_RS10185
uniprot id: Q8EPW0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

221109:OB RS07975
gene id: 221109:OB_RS07975
uniprot id: Q8EQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

221109:OB RS12285
gene id: 221109:OB_RS12285
uniprot id: Q8ENT6
names: Similarity
messages: Belongs to the DinB family.

221109:OB RS13550
gene id: 221109:OB_RS13550
uniprot id: P59350
names: Similarity
messages: Belongs to the UPF0229 family.

221109:OB RS07720
gene id: 221109:OB_RS07720
uniprot id: Q8ER38
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

221109:OB RS14990
gene id: 221109:OB_RS14990
uniprot id: Q8EMC0
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

221109:OB RS13370
gene id: 221109:OB_RS13370
uniprot id: Q8EN76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

221109:OB RS02830
gene id: 221109:OB_RS02830
uniprot id: Q8ESU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

221109:OB RS01615
gene id: 221109:OB_RS01615
uniprot id: Q8ETI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

221109:OB RS15235
gene id: 221109:OB_RS15235
uniprot id: Q8EM74
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

221109:OB RS02395
gene id: 221109:OB_RS02395
uniprot id: Q8ET29
names: Similarity
messages: Belongs to the catalase family.

221109:OB RS00285
gene id: 221109:OB_RS00285
uniprot id: Q8EU37
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

221109:OB RS12680
gene id: 221109:OB_RS12680
uniprot id: Q8CX98
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

221109:OB RS04415
gene id: 221109:OB_RS04415
uniprot id: Q8CXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fosfomycin resistance protein family. FosB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.

221109:OB RS14395
gene id: 221109:OB_RS14395
uniprot id: Q8EMM5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS01520
gene id: 221109:OB_RS01520
uniprot id: Q8ETK4
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06125
gene id: 221109:OB_RS06125
uniprot id: Q8ERY4
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS03235
gene id: 221109:OB_RS03235
uniprot id: Q8ESM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.
messages: Cell membrane
messages: Membrane

221109:OB RS14885
gene id: 221109:OB_RS14885
uniprot id: Q8EMD5
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS15210
gene id: 221109:OB_RS15210
uniprot id: Q8EM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

221109:OB RS02960
gene id: 221109:OB_RS02960
uniprot id: Q8ESS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

221109:OB RS03025
gene id: 221109:OB_RS03025
uniprot id: Q8ESR0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS06505
gene id: 221109:OB_RS06505
uniprot id: Q8ERR2
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

221109:OB RS09605
gene id: 221109:OB_RS09605
uniprot id: Q8CXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

221109:OB RS07120
gene id: 221109:OB_RS07120
uniprot id: Q8ERE3
names: Similarity
messages: Belongs to the peptidase S13 family.

221109:OB RS02845
gene id: 221109:OB_RS02845
uniprot id: Q8ESU2
names: Similarity
messages: Belongs to the TrpC family.

221109:OB RS15685
gene id: 221109:OB_RS15685
uniprot id: Q8CX72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS12230
gene id: 221109:OB_RS12230
uniprot id: Q8ENU8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

221109:OB RS13620
gene id: 221109:OB_RS13620
uniprot id: Q8EN29
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

221109:OB RS17730
gene id: 221109:OB_RS17730
uniprot id: Q8EKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

221109:OB RS03730
gene id: 221109:OB_RS03730
uniprot id: Q8ESF5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08450
gene id: 221109:OB_RS08450
uniprot id: Q8CXG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

221109:OB RS16560
gene id: 221109:OB_RS16560
uniprot id: Q8ELH7
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS10580
gene id: 221109:OB_RS10580
uniprot id: Q8EPN7
names: Similarity
messages: Belongs to the UPF0758 family.

221109:OB RS05800
gene id: 221109:OB_RS05800
uniprot id: Q8CUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

221109:OB RS11465
gene id: 221109:OB_RS11465
uniprot id: Q8EP84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

221109:OB RS02575
gene id: 221109:OB_RS02575
uniprot id: Q8ESZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

221109:OB RS10420
gene id: 221109:OB_RS10420
uniprot id: Q8CXC6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

221109:OB RS04750
gene id: 221109:OB_RS04750
uniprot id: Q8CV64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

221109:OB RS07730
gene id: 221109:OB_RS07730
uniprot id: Q8CXH8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

221109:OB RS16530
gene id: 221109:OB_RS16530
uniprot id: Q8ELI3
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06995
gene id: 221109:OB_RS06995
uniprot id: Q8ERG6
names: Subcellular Location Annotation
messages: Cell membrane

221109:OB RS09545
gene id: 221109:OB_RS09545
uniprot id: Q8EQ58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

221109:OB RS11520
gene id: 221109:OB_RS11520
uniprot id: Q8EP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS12715
gene id: 221109:OB_RS12715
uniprot id: Q8ENK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

221109:OB RS10065
gene id: 221109:OB_RS10065
uniprot id: Q8EPX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

221109:OB RS00965
gene id: 221109:OB_RS00965
uniprot id: Q8ETU3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS03375
gene id: 221109:OB_RS03375
uniprot id: Q8CXL6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

221109:OB RS02970
gene id: 221109:OB_RS02970
uniprot id: Q8ESS0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

221109:OB RS10290
gene id: 221109:OB_RS10290
uniprot id: Q8EPU0
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

221109:OB RS07450
gene id: 221109:OB_RS07450
uniprot id: Q8ER78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

221109:OB RS16080
gene id: 221109:OB_RS16080
uniprot id: Q8ELR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

221109:OB RS08635
gene id: 221109:OB_RS08635
uniprot id: Q8EQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

221109:OB RS12050
gene id: 221109:OB_RS12050
uniprot id: Q8ENY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

221109:OB RS06865
gene id: 221109:OB_RS06865
uniprot id: Q8ERJ1
names: Similarity
messages: Belongs to the WXG100 family.

221109:OB RS00755
gene id: 221109:OB_RS00755
uniprot id: Q8ETY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

221109:OB RS00880
gene id: 221109:OB_RS00880
uniprot id: Q8ETV9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

221109:OB RS07170
gene id: 221109:OB_RS07170
uniprot id: Q8ERD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

221109:OB RS12785
gene id: 221109:OB_RS12785
uniprot id: Q8ENJ3
names: Similarity
messages: Belongs to the peptidase S41A family.

221109:OB RS15530
gene id: 221109:OB_RS15530
uniprot id: Q8EM16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

221109:OB RS07320
gene id: 221109:OB_RS07320
uniprot id: Q8ERA1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS04015
gene id: 221109:OB_RS04015
uniprot id: Q8ES98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

221109:OB RS08400
gene id: 221109:OB_RS08400
uniprot id: Q8CXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

221109:OB RS15425
gene id: 221109:OB_RS15425
uniprot id: P59104
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CwlJ family.
messages: Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination.
messages: Secreted

221109:OB RS09820
gene id: 221109:OB_RS09820
uniprot id: Q8CXD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

221109:OB RS12670
gene id: 221109:OB_RS12670
uniprot id: Q8ENL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

221109:OB RS12295
gene id: 221109:OB_RS12295
uniprot id: Q8ENT4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS08445
gene id: 221109:OB_RS08445
uniprot id: Q8EQR0
names: Similarity
messages: Belongs to the Dps family.

221109:OB RS11980
gene id: 221109:OB_RS11980
uniprot id: Q8ENZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

221109:OB RS13455
gene id: 221109:OB_RS13455
uniprot id: Q8EN59
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS00290
gene id: 221109:OB_RS00290
uniprot id: Q8EU36
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

221109:OB RS10400
gene id: 221109:OB_RS10400
uniprot id: Q8EPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

221109:OB RS05235
gene id: 221109:OB_RS05235
uniprot id: Q8CUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

221109:OB RS12445
gene id: 221109:OB_RS12445
uniprot id: Q8ENQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

221109:OB RS07390
gene id: 221109:OB_RS07390
uniprot id: Q8ER92
names: Similarity
messages: Belongs to the UPF0637 family.

221109:OB RS17685
gene id: 221109:OB_RS17685
uniprot id: Q8EKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS07340
gene id: 221109:OB_RS07340
uniprot id: Q8ER97
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

221109:OB RS08390
gene id: 221109:OB_RS08390
uniprot id: Q8EQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

221109:OB RS16355
gene id: 221109:OB_RS16355
uniprot id: Q8ELL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS17790
gene id: 221109:OB_RS17790
uniprot id: Q8EKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

221109:OB RS06450
gene id: 221109:OB_RS06450
uniprot id: Q8ERS1
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

221109:OB RS13080
gene id: 221109:OB_RS13080
uniprot id: Q8END5
names: Similarity
messages: Belongs to the arginase family.

221109:OB RS01310
gene id: 221109:OB_RS01310
uniprot id: Q8ETN5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

221109:OB RS11965
gene id: 221109:OB_RS11965
uniprot id: Q8ENZ5
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

221109:OB RS14650
gene id: 221109:OB_RS14650
uniprot id: Q8CZD4
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

221109:OB RS12385
gene id: 221109:OB_RS12385
uniprot id: Q8ENR6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

221109:OB RS12335
gene id: 221109:OB_RS12335
uniprot id: Q8ENS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

221109:OB RS06880
gene id: 221109:OB_RS06880
uniprot id: Q8ERI8
names: Similarity
messages: Belongs to the EsaB family.

221109:OB RS13975
gene id: 221109:OB_RS13975
uniprot id: Q8EMV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. Is involved in a myo-inositol catabolic pathway. Bicarbonate, and not CO2, is the end-product of the enzymatic reaction.
messages: Homotetramer.

221109:OB RS01725
gene id: 221109:OB_RS01725
uniprot id: Q8ETG4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

221109:OB RS11775
gene id: 221109:OB_RS11775
uniprot id: Q8EP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

221109:OB RS12120
gene id: 221109:OB_RS12120
uniprot id: Q8ENW9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

221109:OB RS04405
gene id: 221109:OB_RS04405
uniprot id: Q8ES20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

221109:OB RS02455
gene id: 221109:OB_RS02455
uniprot id: Q8ET17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

221109:OB RS13680
gene id: 221109:OB_RS13680
uniprot id: Q8EN17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

221109:OB RS07805
gene id: 221109:OB_RS07805
uniprot id: Q8ER26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

221109:OB RS06680
gene id: 221109:OB_RS06680
uniprot id: Q8ERM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS09415
gene id: 221109:OB_RS09415
uniprot id: Q8EQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SscA family.
messages: Membrane

221109:OB RS11480
gene id: 221109:OB_RS11480
uniprot id: Q8EP82
names: Similarity
messages: Belongs to the UPF0354 family.

221109:OB RS15800
gene id: 221109:OB_RS15800
uniprot id: Q8ELW5
names: Similarity
messages: Belongs to the glutamate synthase family.

221109:OB RS07650
gene id: 221109:OB_RS07650
uniprot id: Q8CXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
messages: Self-associates. Interacts with SigE. Interacts with SpoIIR.

221109:OB RS11250
gene id: 221109:OB_RS11250
uniprot id: Q8EPC2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

221109:OB RS14455
gene id: 221109:OB_RS14455
uniprot id: Q8EML3
names: Similarity
messages: Belongs to the peptidase M24B family.

221109:OB RS11435
gene id: 221109:OB_RS11435
uniprot id: Q8EP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

221109:OB RS00400
gene id: 221109:OB_RS00400
uniprot id: Q8EU18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

221109:OB RS15525
gene id: 221109:OB_RS15525
uniprot id: Q8EM17
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

221109:OB RS16740
gene id: 221109:OB_RS16740
uniprot id: Q8ELE3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

221109:OB RS13355
gene id: 221109:OB_RS13355
uniprot id: Q8EN79
names: Similarity
messages: Belongs to the asparagine synthetase family.

221109:OB RS02200
gene id: 221109:OB_RS02200
uniprot id: Q8ET67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

221109:OB RS00685
gene id: 221109:OB_RS00685
uniprot id: Q8ETZ3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

221109:OB RS15825
gene id: 221109:OB_RS15825
uniprot id: Q8ELW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

221109:OB RS02085
gene id: 221109:OB_RS02085
uniprot id: Q8ET90
names: Function
names: Similarity
messages: Belongs to the LutC/YkgG family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.

221109:OB RS12410
gene id: 221109:OB_RS12410
uniprot id: Q8ENR1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

221109:OB RS10050
gene id: 221109:OB_RS10050
uniprot id: Q8EPY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

221109:OB RS04345
gene id: 221109:OB_RS04345
uniprot id: Q8ES32
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

221109:OB RS16520
gene id: 221109:OB_RS16520
uniprot id: Q8ELI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS09470
gene id: 221109:OB_RS09470
uniprot id: Q8EQ72
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

221109:OB RS10840
gene id: 221109:OB_RS10840
uniprot id: Q8EPJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

221109:OB RS05600
gene id: 221109:OB_RS05600
uniprot id: Q8CUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

221109:OB RS02055
gene id: 221109:OB_RS02055
uniprot id: Q8ET95
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

221109:OB RS09375
gene id: 221109:OB_RS09375
uniprot id: Q8EQ88
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS13275
gene id: 221109:OB_RS13275
uniprot id: Q8EN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

221109:OB RS09085
gene id: 221109:OB_RS09085
uniprot id: Q8EQD7
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS15380
gene id: 221109:OB_RS15380
uniprot id: Q8EM45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

221109:OB RS15410
gene id: 221109:OB_RS15410
uniprot id: Q8EM39
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

221109:OB RS10060
gene id: 221109:OB_RS10060
uniprot id: Q8EPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

221109:OB RS05380
gene id: 221109:OB_RS05380
uniprot id: Q8CUV1
names: Subcellular Location Annotation
messages: Cell membrane

221109:OB RS07470
gene id: 221109:OB_RS07470
uniprot id: Q8ER75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

221109:OB RS13675
gene id: 221109:OB_RS13675
uniprot id: Q8EN18
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

221109:OB RS07335
gene id: 221109:OB_RS07335
uniprot id: Q8ER98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

221109:OB RS16370
gene id: 221109:OB_RS16370
uniprot id: Q8ELL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

221109:OB RS11120
gene id: 221109:OB_RS11120
uniprot id: Q8EPE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

221109:OB RS09175
gene id: 221109:OB_RS09175
uniprot id: Q8EQB9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

221109:OB RS04125
gene id: 221109:OB_RS04125
uniprot id: Q8ES78
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

221109:OB RS02545
gene id: 221109:OB_RS02545
uniprot id: Q8ET00
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

221109:OB RS10490
gene id: 221109:OB_RS10490
uniprot id: Q8EPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

221109:OB RS12020
gene id: 221109:OB_RS12020
uniprot id: Q8ENY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS15910
gene id: 221109:OB_RS15910
uniprot id: Q8ELU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS02325
gene id: 221109:OB_RS02325
uniprot id: Q8ET42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

221109:OB RS04810
gene id: 221109:OB_RS04810
uniprot id: Q8CV52
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

221109:OB RS01405
gene id: 221109:OB_RS01405
uniprot id: Q8ETM5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS04780
gene id: 221109:OB_RS04780
uniprot id: Q8CV58
names: Similarity
messages: Belongs to the UPF0374 family.

221109:OB RS00160
gene id: 221109:OB_RS00160
uniprot id: Q8EU59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

221109:OB RS18715
gene id: 221109:OB_RS18715
uniprot id: Q8EU54
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

221109:OB RS09225
gene id: 221109:OB_RS09225
uniprot id: Q8EQB2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

221109:OB RS00770
gene id: 221109:OB_RS00770
uniprot id: Q8ETX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

221109:OB RS12740
gene id: 221109:OB_RS12740
uniprot id: Q8CX97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

221109:OB RS09550
gene id: 221109:OB_RS09550
uniprot id: Q8EQ57
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS01375
gene id: 221109:OB_RS01375
uniprot id: Q8ETN0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.
messages: Binds 1 Zn(2+) ion per subunit.
messages: Is processed by three successive proteolytic events. First, the extracellular region of RsiW is cleaved by PrsW (Site-1 cleavage) in response to cell envelope stresses. Next, it undergoes cleavage at an intramembrane site (Site-2 cleavage) mediated by RasP. This cleavage uncovers a cryptic proteolytic tag with conserved alanine residues in the transmembrane segment, that is recognized mainly by the ClpXP protease, which completely degrades the protein in the cytoplasm and leads to the induction of the sigma-W-controlled genes (By similarity).
messages: Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation (By similarity).
messages: Membrane

221109:OB RS01140
gene id: 221109:OB_RS01140
uniprot id: Q8ETR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

221109:OB RS17235
gene id: 221109:OB_RS17235
uniprot id: Q8EL49
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

221109:OB RS05695
gene id: 221109:OB_RS05695
uniprot id: Q8CUN5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08290
gene id: 221109:OB_RS08290
uniprot id: Q8CXG8
names: Similarity
messages: Belongs to the ribF family.

221109:OB RS11350
gene id: 221109:OB_RS11350
uniprot id: Q8EPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

221109:OB RS04765
gene id: 221109:OB_RS04765
uniprot id: Q8CV61
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

221109:OB RS07790
gene id: 221109:OB_RS07790
uniprot id: Q8ER28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

221109:OB RS07260
gene id: 221109:OB_RS07260
uniprot id: Q8ERB3
names: Similarity
messages: Belongs to the EamA transporter family.

221109:OB RS12710
gene id: 221109:OB_RS12710
uniprot id: Q8ENK7
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

221109:OB RS15135
gene id: 221109:OB_RS15135
uniprot id: Q8EM93
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

221109:OB RS11355
gene id: 221109:OB_RS11355
uniprot id: Q8EPA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

221109:OB RS08090
gene id: 221109:OB_RS08090
uniprot id: Q8EQX6
names: Similarity
messages: Belongs to the FlgD family.

221109:OB RS12865
gene id: 221109:OB_RS12865
uniprot id: Q8ENH6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

221109:OB RS06805
gene id: 221109:OB_RS06805
uniprot id: Q8ERK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

221109:OB RS00875
gene id: 221109:OB_RS00875
uniprot id: P59373
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

221109:OB RS09155
gene id: 221109:OB_RS09155
uniprot id: Q8EQC3
names: Similarity
messages: Belongs to the UPF0302 family.

221109:OB RS12105
gene id: 221109:OB_RS12105
uniprot id: Q8ENX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS14130
gene id: 221109:OB_RS14130
uniprot id: Q8EMS5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

221109:OB RS09585
gene id: 221109:OB_RS09585
uniprot id: Q8CXE9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

221109:OB RS09405
gene id: 221109:OB_RS09405
uniprot id: Q8EQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

221109:OB RS03755
gene id: 221109:OB_RS03755
uniprot id: Q8ESF0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

221109:OB RS14970
gene id: 221109:OB_RS14970
uniprot id: Q8CVB2
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS07250
gene id: 221109:OB_RS07250
uniprot id: Q8ERB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

221109:OB RS11555
gene id: 221109:OB_RS11555
uniprot id: Q8EP69
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

221109:OB RS15090
gene id: 221109:OB_RS15090
uniprot id: Q8EMA1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

221109:OB RS00775
gene id: 221109:OB_RS00775
uniprot id: P59182
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

221109:OB RS09695
gene id: 221109:OB_RS09695
uniprot id: Q8EQ38
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

221109:OB RS13405
gene id: 221109:OB_RS13405
uniprot id: Q8EN69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

221109:OB RS16100
gene id: 221109:OB_RS16100
uniprot id: Q8CX68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

221109:OB RS12340
gene id: 221109:OB_RS12340
uniprot id: Q8ENS5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00710
gene id: 221109:OB_RS00710
uniprot id: Q8ETY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

221109:OB RS05980
gene id: 221109:OB_RS05980
uniprot id: Q8CUH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

221109:OB RS03005
gene id: 221109:OB_RS03005
uniprot id: Q8ESR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

221109:OB RS13055
gene id: 221109:OB_RS13055
uniprot id: Q8CX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

221109:OB RS04480
gene id: 221109:OB_RS04480
uniprot id: Q8ES06
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

221109:OB RS03540
gene id: 221109:OB_RS03540
uniprot id: Q8ESJ0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

221109:OB RS17270
gene id: 221109:OB_RS17270
uniprot id: Q8EL43
names: Similarity
messages: Belongs to the BMP lipoprotein family.

221109:OB RS12475
gene id: 221109:OB_RS12475
uniprot id: Q8ENP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

221109:OB RS11905
gene id: 221109:OB_RS11905
uniprot id: Q8EP05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

221109:OB RS10835
gene id: 221109:OB_RS10835
uniprot id: Q8EPJ7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

221109:OB RS02370
gene id: 221109:OB_RS02370
uniprot id: Q8ET34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS07115
gene id: 221109:OB_RS07115
uniprot id: Q8ERE4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

221109:OB RS13900
gene id: 221109:OB_RS13900
uniprot id: Q8EMX2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

221109:OB RS03135
gene id: 221109:OB_RS03135
uniprot id: Q8CXM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

221109:OB RS00820
gene id: 221109:OB_RS00820
uniprot id: Q8ETW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

221109:OB RS02125
gene id: 221109:OB_RS02125
uniprot id: Q8ET82
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

221109:OB RS17860
gene id: 221109:OB_RS17860
uniprot id: Q8ERI3
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

221109:OB RS17625
gene id: 221109:OB_RS17625
uniprot id: Q8EKX2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

221109:OB RS13025
gene id: 221109:OB_RS13025
uniprot id: Q8ENE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

221109:OB RS02820
gene id: 221109:OB_RS02820
uniprot id: Q8ESU7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

221109:OB RS10105
gene id: 221109:OB_RS10105
uniprot id: Q8EPX1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS13815
gene id: 221109:OB_RS13815
uniprot id: Q8EMY9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS14560
gene id: 221109:OB_RS14560
uniprot id: Q8EMJ2
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS11025
gene id: 221109:OB_RS11025
uniprot id: Q8CZE2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

221109:OB RS12660
gene id: 221109:OB_RS12660
uniprot id: Q8ENL6
names: Similarity
messages: Belongs to the HPr family.

221109:OB RS08100
gene id: 221109:OB_RS08100
uniprot id: Q8EQX4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

221109:OB RS07910
gene id: 221109:OB_RS07910
uniprot id: Q8ER05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

221109:OB RS11180
gene id: 221109:OB_RS11180
uniprot id: Q8EPD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

221109:OB RS12505
gene id: 221109:OB_RS12505
uniprot id: Q8ENP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

221109:OB RS09860
gene id: 221109:OB_RS09860
uniprot id: Q8EQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

221109:OB RS12820
gene id: 221109:OB_RS12820
uniprot id: Q8ENI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

221109:OB RS01355
gene id: 221109:OB_RS01355
uniprot id: Q8ETN3
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

221109:OB RS12395
gene id: 221109:OB_RS12395
uniprot id: Q8ENR4
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS14470
gene id: 221109:OB_RS14470
uniprot id: Q8EML0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

221109:OB RS15200
gene id: 221109:OB_RS15200
uniprot id: Q8EM81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

221109:OB RS17550
gene id: 221109:OB_RS17550
uniprot id: Q8EKY7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS17720
gene id: 221109:OB_RS17720
uniprot id: Q8EKV3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

221109:OB RS08440
gene id: 221109:OB_RS08440
uniprot id: Q8EQR1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

221109:OB RS12845
gene id: 221109:OB_RS12845
uniprot id: Q8ENI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

221109:OB RS17560
gene id: 221109:OB_RS17560
uniprot id: Q8EKY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

221109:OB RS02080
gene id: 221109:OB_RS02080
uniprot id: Q8ET91
names: Function
names: Similarity
messages: Belongs to the LutB/YkgF family.
messages: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate.

221109:OB RS02955
gene id: 221109:OB_RS02955
uniprot id: Q8CXM8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

221109:OB RS03220
gene id: 221109:OB_RS03220
uniprot id: Q8ESM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS07435
gene id: 221109:OB_RS07435
uniprot id: Q8ER83
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

221109:OB RS14840
gene id: 221109:OB_RS14840
uniprot id: Q8EME2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

221109:OB RS13165
gene id: 221109:OB_RS13165
uniprot id: Q8ENB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS02705
gene id: 221109:OB_RS02705
uniprot id: Q8ESW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

221109:OB RS17385
gene id: 221109:OB_RS17385
uniprot id: Q8EL20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

221109:OB RS06230
gene id: 221109:OB_RS06230
uniprot id: Q8ERW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

221109:OB RS00795
gene id: 221109:OB_RS00795
uniprot id: Q8ETX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

221109:OB RS08055
gene id: 221109:OB_RS08055
uniprot id: Q8EQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

221109:OB RS16635
gene id: 221109:OB_RS16635
uniprot id: Q8ELG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

221109:OB RS10695
gene id: 221109:OB_RS10695
uniprot id: Q8CXB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

221109:OB RS15605
gene id: 221109:OB_RS15605
uniprot id: Q8CX73
names: Similarity
messages: Belongs to the RutC family.

221109:OB RS00970
gene id: 221109:OB_RS00970
uniprot id: Q8ETU2
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS09000
gene id: 221109:OB_RS09000
uniprot id: Q8EQF3
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15510
gene id: 221109:OB_RS15510
uniprot id: Q8EM20
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

221109:OB RS15645
gene id: 221109:OB_RS15645
uniprot id: Q8ELZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS03765
gene id: 221109:OB_RS03765
uniprot id: Q8ESE8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

221109:OB RS14790
gene id: 221109:OB_RS14790
uniprot id: Q8EMF2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

221109:OB RS00695
gene id: 221109:OB_RS00695
uniprot id: Q8ETZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

221109:OB RS11380
gene id: 221109:OB_RS11380
uniprot id: Q8EP98
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

221109:OB RS00700
gene id: 221109:OB_RS00700
uniprot id: Q8ETZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

221109:OB RS15990
gene id: 221109:OB_RS15990
uniprot id: Q8ELT0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS11950
gene id: 221109:OB_RS11950
uniprot id: Q8ENZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS00750
gene id: 221109:OB_RS00750
uniprot id: Q8ETY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

221109:OB RS10815
gene id: 221109:OB_RS10815
uniprot id: Q8EPJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

221109:OB RS10605
gene id: 221109:OB_RS10605
uniprot id: Q8EPN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

221109:OB RS03725
gene id: 221109:OB_RS03725
uniprot id: Q8ESF6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08975
gene id: 221109:OB_RS08975
uniprot id: Q8EQF9
names: Similarity
messages: Belongs to the peptidase C40 family.

221109:OB RS13920
gene id: 221109:OB_RS13920
uniprot id: Q8EMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS04055
gene id: 221109:OB_RS04055
uniprot id: Q8ES91
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

221109:OB RS12590
gene id: 221109:OB_RS12590
uniprot id: Q8ENM8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS15965
gene id: 221109:OB_RS15965
uniprot id: Q8ELT5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12180
gene id: 221109:OB_RS12180
uniprot id: Q8ENV7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS11175
gene id: 221109:OB_RS11175
uniprot id: Q8EPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

221109:OB RS12220
gene id: 221109:OB_RS12220
uniprot id: Q8ENV0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

221109:OB RS10640
gene id: 221109:OB_RS10640
uniprot id: Q8CXC0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

221109:OB RS13915
gene id: 221109:OB_RS13915
uniprot id: Q8EMW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

221109:OB RS12665
gene id: 221109:OB_RS12665
uniprot id: Q8ENL5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

221109:OB RS03300
gene id: 221109:OB_RS03300
uniprot id: Q8ESL2
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS09785
gene id: 221109:OB_RS09785
uniprot id: Q8CXE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

221109:OB RS09885
gene id: 221109:OB_RS09885
uniprot id: Q8EQ06
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS13825
gene id: 221109:OB_RS13825
uniprot id: Q8EMY7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

221109:OB RS08720
gene id: 221109:OB_RS08720
uniprot id: P59250
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

221109:OB RS02285
gene id: 221109:OB_RS02285
uniprot id: Q8ET50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metal hydrolase YfiT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Possible metal-dependent hydrolase.

221109:OB RS12240
gene id: 221109:OB_RS12240
uniprot id: Q8ENU6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

221109:OB RS14895
gene id: 221109:OB_RS14895
uniprot id: Q8CX83
names: Similarity
messages: Belongs to the CapA family.

221109:OB RS05910
gene id: 221109:OB_RS05910
uniprot id: Q8CUJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

221109:OB RS02555
gene id: 221109:OB_RS02555
uniprot id: Q8ESZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS16215
gene id: 221109:OB_RS16215
uniprot id: Q8ELP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

221109:OB RS10150
gene id: 221109:OB_RS10150
uniprot id: Q8CXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

221109:OB RS15230
gene id: 221109:OB_RS15230
uniprot id: Q8EM75
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS10300
gene id: 221109:OB_RS10300
uniprot id: Q8EPT9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

221109:OB RS07965
gene id: 221109:OB_RS07965
uniprot id: Q8EQZ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

221109:OB RS05240
gene id: 221109:OB_RS05240
uniprot id: Q8CUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS03395
gene id: 221109:OB_RS03395
uniprot id: Q8ESK1
names: Similarity
messages: Belongs to the catalase family.

221109:OB RS16505
gene id: 221109:OB_RS16505
uniprot id: Q8ELI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS11065
gene id: 221109:OB_RS11065
uniprot id: Q8EPF6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

221109:OB RS10795
gene id: 221109:OB_RS10795
uniprot id: Q8EPK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

221109:OB RS09510
gene id: 221109:OB_RS09510
uniprot id: Q8EQ65
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

221109:OB RS05810
gene id: 221109:OB_RS05810
uniprot id: Q8CUL2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

221109:OB RS07535
gene id: 221109:OB_RS07535
uniprot id: Q8ER64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

221109:OB RS08280
gene id: 221109:OB_RS08280
uniprot id: Q8EQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

221109:OB RS10590
gene id: 221109:OB_RS10590
uniprot id: Q8EPN5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

221109:OB RS11590
gene id: 221109:OB_RS11590
uniprot id: Q8EP62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

221109:OB RS10305
gene id: 221109:OB_RS10305
uniprot id: Q8EPT8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

221109:OB RS08705
gene id: 221109:OB_RS08705
uniprot id: Q8EQL1
names: Similarity
messages: Belongs to the HesB/IscA family.

221109:OB RS12460
gene id: 221109:OB_RS12460
uniprot id: Q8ENQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.

221109:OB RS02670
gene id: 221109:OB_RS02670
uniprot id: Q8ESX6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS16040
gene id: 221109:OB_RS16040
uniprot id: Q8ELS1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

221109:OB RS05305
gene id: 221109:OB_RS05305
uniprot id: Q8CUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

221109:OB RS03830
gene id: 221109:OB_RS03830
uniprot id: Q8ESD6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06170
gene id: 221109:OB_RS06170
uniprot id: Q8ERX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

221109:OB RS00625
gene id: 221109:OB_RS00625
uniprot id: Q8EU05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

221109:OB RS16140
gene id: 221109:OB_RS16140
uniprot id: Q8ELQ3
names: Similarity
messages: Belongs to the peptidase M20A family.

221109:OB RS17620
gene id: 221109:OB_RS17620
uniprot id: Q8EKX3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

221109:OB RS02030
gene id: 221109:OB_RS02030
uniprot id: Q8ETA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS01960
gene id: 221109:OB_RS01960
uniprot id: Q8ETB4
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05580
gene id: 221109:OB_RS05580
uniprot id: Q8CUQ9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS02385
gene id: 221109:OB_RS02385
uniprot id: Q8ET31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

221109:OB RS00675
gene id: 221109:OB_RS00675
uniprot id: Q8ETZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

221109:OB RS15040
gene id: 221109:OB_RS15040
uniprot id: Q8EMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

221109:OB RS02610
gene id: 221109:OB_RS02610
uniprot id: Q8ESY6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS04805
gene id: 221109:OB_RS04805
uniprot id: Q8CV53
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

221109:OB RS00740
gene id: 221109:OB_RS00740
uniprot id: Q8ETY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

221109:OB RS15125
gene id: 221109:OB_RS15125
uniprot id: Q8EM95
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS03270
gene id: 221109:OB_RS03270
uniprot id: Q8ESL7
names: Similarity
messages: Belongs to the DEAD box helicase family.

221109:OB RS14995
gene id: 221109:OB_RS14995
uniprot id: Q8EMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

221109:OB RS15100
gene id: 221109:OB_RS15100
uniprot id: Q8EM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

221109:OB RS15640
gene id: 221109:OB_RS15640
uniprot id: Q8ELZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS03080
gene id: 221109:OB_RS03080
uniprot id: Q8ESP9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

221109:OB RS04455
gene id: 221109:OB_RS04455
uniprot id: Q8ES10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

221109:OB RS03325
gene id: 221109:OB_RS03325
uniprot id: Q8ESK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS07305
gene id: 221109:OB_RS07305
uniprot id: Q8ERA4
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

221109:OB RS15740
gene id: 221109:OB_RS15740
uniprot id: Q8ELX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

221109:OB RS03825
gene id: 221109:OB_RS03825
uniprot id: Q8ESD7
names: Similarity
messages: Belongs to the peptidase C56 family.

221109:OB RS13555
gene id: 221109:OB_RS13555
uniprot id: Q8EN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

221109:OB RS06355
gene id: 221109:OB_RS06355
uniprot id: Q8ERT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

221109:OB RS11060
gene id: 221109:OB_RS11060
uniprot id: Q8EPF7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

221109:OB RS11635
gene id: 221109:OB_RS11635
uniprot id: Q8EP53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS12235
gene id: 221109:OB_RS12235
uniprot id: Q8ENU7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

221109:OB RS06885
gene id: 221109:OB_RS06885
uniprot id: Q8ERI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssB family.
messages: Membrane

221109:OB RS10950
gene id: 221109:OB_RS10950
uniprot id: Q8EPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

221109:OB RS13035
gene id: 221109:OB_RS13035
uniprot id: Q8ENE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS03990
gene id: 221109:OB_RS03990
uniprot id: Q8ESA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

221109:OB RS10405
gene id: 221109:OB_RS10405
uniprot id: Q8EPR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS00010
gene id: 221109:OB_RS00010
uniprot id: Q8EU88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

221109:OB RS17750
gene id: 221109:OB_RS17750
uniprot id: Q8EKU7
names: Similarity
messages: Belongs to the ParB family.

221109:OB RS10430
gene id: 221109:OB_RS10430
uniprot id: Q8EPR4
names: Similarity
messages: Belongs to the RecJ family.

221109:OB RS11725
gene id: 221109:OB_RS11725
uniprot id: Q8EP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

221109:OB RS03265
gene id: 221109:OB_RS03265
uniprot id: Q8ESL8
names: Similarity
messages: Belongs to the EamA transporter family.

221109:OB RS17260
gene id: 221109:OB_RS17260
uniprot id: Q8EL45
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00650
gene id: 221109:OB_RS00650
uniprot id: Q8ETZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

221109:OB RS11580
gene id: 221109:OB_RS11580
uniprot id: Q8EP64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

221109:OB RS15330
gene id: 221109:OB_RS15330
uniprot id: Q8EM54
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

221109:OB RS16085
gene id: 221109:OB_RS16085
uniprot id: Q8ELR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS09210
gene id: 221109:OB_RS09210
uniprot id: Q8CWG0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

221109:OB RS11690
gene id: 221109:OB_RS11690
uniprot id: Q8EP44
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

221109:OB RS02780
gene id: 221109:OB_RS02780
uniprot id: Q8ESV5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

221109:OB RS15480
gene id: 221109:OB_RS15480
uniprot id: Q8EM25
names: Subcellular Location Annotation
messages: Cell membrane

221109:OB RS12570
gene id: 221109:OB_RS12570
uniprot id: Q8ENN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS13195
gene id: 221109:OB_RS13195
uniprot id: Q8ENB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.
messages: The complex is composed of an ATP-binding protein (RbsA), two transmembrane proteins (RbsC) and a solute-binding protein (RbsB).

221109:OB RS17785
gene id: 221109:OB_RS17785
uniprot id: Q8CX53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

221109:OB RS04090
gene id: 221109:OB_RS04090
uniprot id: Q8ES84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

221109:OB RS04645
gene id: 221109:OB_RS04645
uniprot id: Q8CV85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

221109:OB RS17390
gene id: 221109:OB_RS17390
uniprot id: Q8EL19
names: Similarity
messages: Belongs to the UPF0309 family.

221109:OB RS00230
gene id: 221109:OB_RS00230
uniprot id: Q8EU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

221109:OB RS17515
gene id: 221109:OB_RS17515
uniprot id: Q8EKZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

221109:OB RS04615
gene id: 221109:OB_RS04615
uniprot id: Q8CV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

221109:OB RS12935
gene id: 221109:OB_RS12935
uniprot id: Q8ENG2
names: Similarity
messages: Belongs to the IMPACT family.

221109:OB RS05645
gene id: 221109:OB_RS05645
uniprot id: Q8CUP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

221109:OB RS02865
gene id: 221109:OB_RS02865
uniprot id: Q8EST8
names: Similarity
messages: Belongs to the nitroreductase family.

221109:OB RS10485
gene id: 221109:OB_RS10485
uniprot id: Q8EPQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

221109:OB RS08685
gene id: 221109:OB_RS08685
uniprot id: Q8EQL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

221109:OB RS07680
gene id: 221109:OB_RS07680
uniprot id: Q8ER44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

221109:OB RS02860
gene id: 221109:OB_RS02860
uniprot id: Q8EST9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

221109:OB RS14320
gene id: 221109:OB_RS14320
uniprot id: Q8EMN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS12455
gene id: 221109:OB_RS12455
uniprot id: Q8ENQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

221109:OB RS06660
gene id: 221109:OB_RS06660
uniprot id: Q8ERN2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS14340
gene id: 221109:OB_RS14340
uniprot id: Q8EMN5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

221109:OB RS07345
gene id: 221109:OB_RS07345
uniprot id: Q8ER96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

221109:OB RS15655
gene id: 221109:OB_RS15655
uniprot id: Q8ELZ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS09360
gene id: 221109:OB_RS09360
uniprot id: Q8EQ91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS12345
gene id: 221109:OB_RS12345
uniprot id: Q8ENS4
names: Similarity
messages: Belongs to the peptidase C40 family.

221109:OB RS12275
gene id: 221109:OB_RS12275
uniprot id: Q8ENT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

221109:OB RS00315
gene id: 221109:OB_RS00315
uniprot id: Q8CXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

221109:OB RS03965
gene id: 221109:OB_RS03965
uniprot id: Q8ESA8
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS07245
gene id: 221109:OB_RS07245
uniprot id: Q8ERB8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15900
gene id: 221109:OB_RS15900
uniprot id: Q8ELU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

221109:OB RS10240
gene id: 221109:OB_RS10240
uniprot id: Q8EPU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

221109:OB RS12875
gene id: 221109:OB_RS12875
uniprot id: Q8ENH4
names: Similarity
messages: Belongs to the FlgM family.

221109:OB RS09560
gene id: 221109:OB_RS09560
uniprot id: Q8CXF0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

221109:OB RS10220
gene id: 221109:OB_RS10220
uniprot id: Q8EPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

221109:OB RS07110
gene id: 221109:OB_RS07110
uniprot id: Q8CXJ5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

221109:OB RS16600
gene id: 221109:OB_RS16600
uniprot id: Q8ELG9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS15440
gene id: 221109:OB_RS15440
uniprot id: Q8EM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

221109:OB RS13400
gene id: 221109:OB_RS13400
uniprot id: Q8EN70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

221109:OB RS10270
gene id: 221109:OB_RS10270
uniprot id: Q8EPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

221109:OB RS03720
gene id: 221109:OB_RS03720
uniprot id: Q8ESF7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

221109:OB RS05490
gene id: 221109:OB_RS05490
uniprot id: Q8CUS7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

221109:OB RS00075
gene id: 221109:OB_RS00075
uniprot id: Q8EU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

221109:OB RS08730
gene id: 221109:OB_RS08730
uniprot id: Q8EQK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

221109:OB RS17025
gene id: 221109:OB_RS17025
uniprot id: Q8EL90
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

221109:OB RS00730
gene id: 221109:OB_RS00730
uniprot id: Q8ETY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

221109:OB RS12315
gene id: 221109:OB_RS12315
uniprot id: Q8ENT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

221109:OB RS03785
gene id: 221109:OB_RS03785
uniprot id: Q8ESE4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

221109:OB RS13715
gene id: 221109:OB_RS13715
uniprot id: Q8EN10
names: Similarity
messages: Belongs to the TelA family.

221109:OB RS08550
gene id: 221109:OB_RS08550
uniprot id: Q8EQP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

221109:OB RS16025
gene id: 221109:OB_RS16025
uniprot id: Q8ELS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

221109:OB RS05730
gene id: 221109:OB_RS05730
uniprot id: Q8CUM8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

221109:OB RS16245
gene id: 221109:OB_RS16245
uniprot id: Q8CX65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

221109:OB RS04775
gene id: 221109:OB_RS04775
uniprot id: Q8CV59
names: Similarity
messages: Belongs to the gamma-type SASP family.

221109:OB RS13290
gene id: 221109:OB_RS13290
uniprot id: Q8EN92
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

221109:OB RS14185
gene id: 221109:OB_RS14185
uniprot id: Q8EMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS05765
gene id: 221109:OB_RS05765
uniprot id: Q8CUM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

221109:OB RS07325
gene id: 221109:OB_RS07325
uniprot id: Q8ERA0
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS02265
gene id: 221109:OB_RS02265
uniprot id: Q8ET55
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

221109:OB RS02950
gene id: 221109:OB_RS02950
uniprot id: Q8ESS3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

221109:OB RS05700
gene id: 221109:OB_RS05700
uniprot id: Q8CUN4
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07370
gene id: 221109:OB_RS07370
uniprot id: Q8CXJ0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

221109:OB RS10140
gene id: 221109:OB_RS10140
uniprot id: Q8CXD3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

221109:OB RS09005
gene id: 221109:OB_RS09005
uniprot id: Q8EQF2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

221109:OB RS00085
gene id: 221109:OB_RS00085
uniprot id: Q8EU74
names: Similarity
messages: Belongs to the DCK/DGK family.

221109:OB RS12370
gene id: 221109:OB_RS12370
uniprot id: Q8ENR9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

221109:OB RS11495
gene id: 221109:OB_RS11495
uniprot id: Q8EP79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

221109:OB RS15590
gene id: 221109:OB_RS15590
uniprot id: Q8CX74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS03555
gene id: 221109:OB_RS03555
uniprot id: Q8ESI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

221109:OB RS07080
gene id: 221109:OB_RS07080
uniprot id: Q8ERF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS09245
gene id: 221109:OB_RS09245
uniprot id: Q8EQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

221109:OB RS09650
gene id: 221109:OB_RS09650
uniprot id: Q8EQ47
names: Similarity
messages: Belongs to the TlyA family.

221109:OB RS05965
gene id: 221109:OB_RS05965
uniprot id: Q8CUH8
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

221109:OB RS01605
gene id: 221109:OB_RS01605
uniprot id: Q8CXN5
names: Similarity
messages: Belongs to the peptidase C40 family.

221109:OB RS12800
gene id: 221109:OB_RS12800
uniprot id: Q8ENJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

221109:OB RS08640
gene id: 221109:OB_RS08640
uniprot id: Q8EQM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

221109:OB RS16535
gene id: 221109:OB_RS16535
uniprot id: Q8ELI2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

221109:OB RS10285
gene id: 221109:OB_RS10285
uniprot id: Q8EPU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

221109:OB RS01220
gene id: 221109:OB_RS01220
uniprot id: Q8ETQ3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

221109:OB RS12755
gene id: 221109:OB_RS12755
uniprot id: Q8ENJ9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS04635
gene id: 221109:OB_RS04635
uniprot id: Q8CV87
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

221109:OB RS03625
gene id: 221109:OB_RS03625
uniprot id: Q8ESH5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

221109:OB RS13390
gene id: 221109:OB_RS13390
uniprot id: Q8EN72
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS13305
gene id: 221109:OB_RS13305
uniprot id: Q8EN89
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS14555
gene id: 221109:OB_RS14555
uniprot id: Q8EMJ3
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS12905
gene id: 221109:OB_RS12905
uniprot id: Q8ENG8
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS14405
gene id: 221109:OB_RS14405
uniprot id: Q8EMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

221109:OB RS13780
gene id: 221109:OB_RS13780
uniprot id: Q8EMZ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

221109:OB RS02980
gene id: 221109:OB_RS02980
uniprot id: Q8ESR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

221109:OB RS03620
gene id: 221109:OB_RS03620
uniprot id: Q8ESH6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12620
gene id: 221109:OB_RS12620
uniprot id: Q8ENM4
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

221109:OB RS08475
gene id: 221109:OB_RS08475
uniprot id: Q8EQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS03545
gene id: 221109:OB_RS03545
uniprot id: Q8ESI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

221109:OB RS07915
gene id: 221109:OB_RS07915
uniprot id: Q8ER04
names: Similarity
messages: Belongs to the UPF0435 family.

221109:OB RS08250
gene id: 221109:OB_RS08250
uniprot id: Q8EQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

221109:OB RS15355
gene id: 221109:OB_RS15355
uniprot id: Q8EM50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS14655
gene id: 221109:OB_RS14655
uniprot id: Q8EMH4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS05040
gene id: 221109:OB_RS05040
uniprot id: Q8CV19
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

221109:OB RS00255
gene id: 221109:OB_RS00255
uniprot id: Q8EU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

221109:OB RS04000
gene id: 221109:OB_RS04000
uniprot id: Q8ESA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

221109:OB RS16410
gene id: 221109:OB_RS16410
uniprot id: Q8ELK6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08790
gene id: 221109:OB_RS08790
uniprot id: Q8EQJ5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

221109:OB RS10350
gene id: 221109:OB_RS10350
uniprot id: Q8EPS9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

221109:OB RS09900
gene id: 221109:OB_RS09900
uniprot id: Q8EQ04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

221109:OB RS11305
gene id: 221109:OB_RS11305
uniprot id: Q8EPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

221109:OB RS03400
gene id: 221109:OB_RS03400
uniprot id: Q8ESK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

221109:OB RS11995
gene id: 221109:OB_RS11995
uniprot id: Q8ENZ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

221109:OB RS15155
gene id: 221109:OB_RS15155
uniprot id: Q8EM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS13935
gene id: 221109:OB_RS13935
uniprot id: Q8EMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

221109:OB RS10910
gene id: 221109:OB_RS10910
uniprot id: Q8CXB2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

221109:OB RS11840
gene id: 221109:OB_RS11840
uniprot id: Q8EP16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

221109:OB RS16395
gene id: 221109:OB_RS16395
uniprot id: Q8ELK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

221109:OB RS06875
gene id: 221109:OB_RS06875
uniprot id: Q8ERI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssA family.
messages: Cell membrane
messages: Membrane

221109:OB RS09765
gene id: 221109:OB_RS09765
uniprot id: Q8EQ24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS10960
gene id: 221109:OB_RS10960
uniprot id: Q8EPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

221109:OB RS07800
gene id: 221109:OB_RS07800
uniprot id: Q8CXH5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS13315
gene id: 221109:OB_RS13315
uniprot id: Q8EN87
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

221109:OB RS11425
gene id: 221109:OB_RS11425
uniprot id: Q8EP92
names: Similarity
messages: Belongs to the histone deacetylase family.

221109:OB RS08765
gene id: 221109:OB_RS08765
uniprot id: Q8EQK0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

221109:OB RS03775
gene id: 221109:OB_RS03775
uniprot id: Q8ESE6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS08940
gene id: 221109:OB_RS08940
uniprot id: Q8EQG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS15095
gene id: 221109:OB_RS15095
uniprot id: Q8EMA0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

221109:OB RS16440
gene id: 221109:OB_RS16440
uniprot id: Q8ELK1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

221109:OB RS07100
gene id: 221109:OB_RS07100
uniprot id: Q8ERE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

221109:OB RS12250
gene id: 221109:OB_RS12250
uniprot id: Q8ENU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS14665
gene id: 221109:OB_RS14665
uniprot id: Q8CX90
names: Similarity
messages: Belongs to the ribF family.

221109:OB RS16150
gene id: 221109:OB_RS16150
uniprot id: Q8ELQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS01110
gene id: 221109:OB_RS01110
uniprot id: Q8ETR7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05935
gene id: 221109:OB_RS05935
uniprot id: Q8CUI4
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS14490
gene id: 221109:OB_RS14490
uniprot id: Q8EMK6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

221109:OB RS14525
gene id: 221109:OB_RS14525
uniprot id: Q8EMJ9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the regioselective dehydration of galactarate into 2-keto-D-threo-4,5-dihydroxyadipate ((2S,3R)-dihydroxy-5-oxohexanedioate). Is not active on other acid sugars.
messages: The enzyme product is the enantiomer of the product obtained in the galactarate dehydratase reaction catalyzed by STM3697; the enzymes thus differ in their regiochemistry of dehydration.

221109:OB RS07660
gene id: 221109:OB_RS07660
uniprot id: Q8ER48
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

221109:OB RS14700
gene id: 221109:OB_RS14700
uniprot id: Q8EMG9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

221109:OB RS16350
gene id: 221109:OB_RS16350
uniprot id: Q8ELL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS15850
gene id: 221109:OB_RS15850
uniprot id: Q8ELV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

221109:OB RS10625
gene id: 221109:OB_RS10625
uniprot id: Q8CZE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS08230
gene id: 221109:OB_RS08230
uniprot id: Q8EQU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

221109:OB RS15495
gene id: 221109:OB_RS15495
uniprot id: Q8EM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

221109:OB RS07815
gene id: 221109:OB_RS07815
uniprot id: Q8ER24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

221109:OB RS04135
gene id: 221109:OB_RS04135
uniprot id: Q8ES76
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

221109:OB RS15720
gene id: 221109:OB_RS15720
uniprot id: Q8ELY1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15290
gene id: 221109:OB_RS15290
uniprot id: Q8EM61
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

221109:OB RS00805
gene id: 221109:OB_RS00805
uniprot id: Q8ETX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

221109:OB RS15015
gene id: 221109:OB_RS15015
uniprot id: Q8EMB6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

221109:OB RS16070
gene id: 221109:OB_RS16070
uniprot id: Q8ELR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS05415
gene id: 221109:OB_RS05415
uniprot id: Q8CUU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
messages: Homodimer.

221109:OB RS15935
gene id: 221109:OB_RS15935
uniprot id: Q8ELU1
names: Similarity
messages: Belongs to the nitroreductase family.

221109:OB RS09630
gene id: 221109:OB_RS09630
uniprot id: Q8EQ49
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

221109:OB RS17635
gene id: 221109:OB_RS17635
uniprot id: Q8EKX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

221109:OB RS15970
gene id: 221109:OB_RS15970
uniprot id: Q8ELT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

221109:OB RS05720
gene id: 221109:OB_RS05720
uniprot id: Q8CUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

221109:OB RS05540
gene id: 221109:OB_RS05540
uniprot id: Q8CUR7
names: Similarity
messages: Belongs to the ThiD family.

221109:OB RS10650
gene id: 221109:OB_RS10650
uniprot id: Q8EPM7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

221109:OB RS14170
gene id: 221109:OB_RS14170
uniprot id: Q8EMR7
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS05795
gene id: 221109:OB_RS05795
uniprot id: Q8CUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Cell membrane
messages: Multidrug efflux pump.

221109:OB RS16620
gene id: 221109:OB_RS16620
uniprot id: Q8ELG5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

221109:OB RS10895
gene id: 221109:OB_RS10895
uniprot id: Q8CXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

221109:OB RS14060
gene id: 221109:OB_RS14060
uniprot id: Q8EMT8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS13115
gene id: 221109:OB_RS13115
uniprot id: Q8ENC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS10480
gene id: 221109:OB_RS10480
uniprot id: Q8EPQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

221109:OB RS08995
gene id: 221109:OB_RS08995
uniprot id: Q8EQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

221109:OB RS05065
gene id: 221109:OB_RS05065
uniprot id: Q8CV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.

221109:OB RS07640
gene id: 221109:OB_RS07640
uniprot id: Q8CXI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

221109:OB RS02065
gene id: 221109:OB_RS02065
uniprot id: Q8ET94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

221109:OB RS17000
gene id: 221109:OB_RS17000
uniprot id: Q8EL95
names: Function
names: Similarity
messages: A methylase, recognizes the double-stranded sequence 5'-ACCGGT-3', methylates C-? on both strands. No endonuclease has been identified for this methylase.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

221109:OB RS03145
gene id: 221109:OB_RS03145
uniprot id: Q8ESP0
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07775
gene id: 221109:OB_RS07775
uniprot id: Q8ER31
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

221109:OB RS07645
gene id: 221109:OB_RS07645
uniprot id: Q8CXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

221109:OB RS12440
gene id: 221109:OB_RS12440
uniprot id: Q8ENQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

221109:OB RS17900
gene id: 221109:OB_RS17900
uniprot id: Q8ELE0
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

221109:OB RS12860
gene id: 221109:OB_RS12860
uniprot id: Q8ENH7
names: Similarity
messages: Belongs to the bacterial flagellin family.

221109:OB RS13950
gene id: 221109:OB_RS13950
uniprot id: Q8EMV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS16130
gene id: 221109:OB_RS16130
uniprot id: Q8ELQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS17605
gene id: 221109:OB_RS17605
uniprot id: Q8EKX6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS08140
gene id: 221109:OB_RS08140
uniprot id: Q8EQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

221109:OB RS17170
gene id: 221109:OB_RS17170
uniprot id: Q8EL62
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

221109:OB RS01555
gene id: 221109:OB_RS01555
uniprot id: Q8ETJ7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

221109:OB RS12720
gene id: 221109:OB_RS12720
uniprot id: Q8ENK5
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

221109:OB RS08715
gene id: 221109:OB_RS08715
uniprot id: Q8EQK9
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

221109:OB RS07890
gene id: 221109:OB_RS07890
uniprot id: Q8ER09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

221109:OB RS01685
gene id: 221109:OB_RS01685
uniprot id: Q8ETH1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS04590
gene id: 221109:OB_RS04590
uniprot id: Q8CV96
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

221109:OB RS06735
gene id: 221109:OB_RS06735
uniprot id: Q8ERL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

221109:OB RS00960
gene id: 221109:OB_RS00960
uniprot id: Q8ETU4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

221109:OB RS03065
gene id: 221109:OB_RS03065
uniprot id: Q8ESQ2
names: Similarity
messages: Belongs to the peptidase M20A family.

221109:OB RS05275
gene id: 221109:OB_RS05275
uniprot id: Q8CUX2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

221109:OB RS03365
gene id: 221109:OB_RS03365
uniprot id: Q8ESK3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

221109:OB RS08220
gene id: 221109:OB_RS08220
uniprot id: Q8EQV1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

221109:OB RS00850
gene id: 221109:OB_RS00850
uniprot id: Q8ETW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

221109:OB RS17380
gene id: 221109:OB_RS17380
uniprot id: Q8EL21
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

221109:OB RS03780
gene id: 221109:OB_RS03780
uniprot id: Q8ESE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

221109:OB RS02490
gene id: 221109:OB_RS02490
uniprot id: Q8ET11
names: Similarity
messages: Belongs to the UPF0178 family.

221109:OB RS00690
gene id: 221109:OB_RS00690
uniprot id: Q8ETZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

221109:OB RS17080
gene id: 221109:OB_RS17080
uniprot id: Q8EL78
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS12835
gene id: 221109:OB_RS12835
uniprot id: Q8ENI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

221109:OB RS13740
gene id: 221109:OB_RS13740
uniprot id: Q8EN04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

221109:OB RS07695
gene id: 221109:OB_RS07695
uniprot id: Q8CXI0
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS10855
gene id: 221109:OB_RS10855
uniprot id: Q8EPJ4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

221109:OB RS00870
gene id: 221109:OB_RS00870
uniprot id: Q8ETW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

221109:OB RS09185
gene id: 221109:OB_RS09185
uniprot id: Q8EQB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

221109:OB RS02025
gene id: 221109:OB_RS02025
uniprot id: Q8ETA1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06380
gene id: 221109:OB_RS06380
uniprot id: Q8ERT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

221109:OB RS05950
gene id: 221109:OB_RS05950
uniprot id: Q8CUI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS05850
gene id: 221109:OB_RS05850
uniprot id: Q8CUK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS05375
gene id: 221109:OB_RS05375
uniprot id: Q8CUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS10470
gene id: 221109:OB_RS10470
uniprot id: Q8EPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

221109:OB RS10380
gene id: 221109:OB_RS10380
uniprot id: Q8EPS4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS13090
gene id: 221109:OB_RS13090
uniprot id: Q8END3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS13510
gene id: 221109:OB_RS13510
uniprot id: Q8EN49
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

221109:OB RS00025
gene id: 221109:OB_RS00025
uniprot id: Q8EU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

221109:OB RS15895
gene id: 221109:OB_RS15895
uniprot id: Q8CX70
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

221109:OB RS12255
gene id: 221109:OB_RS12255
uniprot id: Q8ENU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

221109:OB RS10970
gene id: 221109:OB_RS10970
uniprot id: Q8EPH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

221109:OB RS09480
gene id: 221109:OB_RS09480
uniprot id: Q8EQ70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

221109:OB RS00295
gene id: 221109:OB_RS00295
uniprot id: Q8EU35
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

221109:OB RS02540
gene id: 221109:OB_RS02540
uniprot id: Q8ET01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

221109:OB RS00165
gene id: 221109:OB_RS00165
uniprot id: Q8EU58
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

221109:OB RS00810
gene id: 221109:OB_RS00810
uniprot id: Q8ETX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

221109:OB RS03750
gene id: 221109:OB_RS03750
uniprot id: Q8ESF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS05345
gene id: 221109:OB_RS05345
uniprot id: Q8CUV8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS13755
gene id: 221109:OB_RS13755
uniprot id: Q8EN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

221109:OB RS15345
gene id: 221109:OB_RS15345
uniprot id: Q8EM52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

221109:OB RS15000
gene id: 221109:OB_RS15000
uniprot id: Q8EMB8
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

221109:OB RS02480
gene id: 221109:OB_RS02480
uniprot id: Q8ET13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS06840
gene id: 221109:OB_RS06840
uniprot id: Q8ERJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

221109:OB RS04790
gene id: 221109:OB_RS04790
uniprot id: Q8CV56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS03895
gene id: 221109:OB_RS03895
uniprot id: Q8ESC4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

221109:OB RS05790
gene id: 221109:OB_RS05790
uniprot id: Q8CUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

221109:OB RS05435
gene id: 221109:OB_RS05435
uniprot id: Q8CUT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

221109:OB RS03035
gene id: 221109:OB_RS03035
uniprot id: P59249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

221109:OB RS06665
gene id: 221109:OB_RS06665
uniprot id: Q8ERN1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

221109:OB RS07980
gene id: 221109:OB_RS07980
uniprot id: Q8EQZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

221109:OB RS00155
gene id: 221109:OB_RS00155
uniprot id: Q8EU60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

221109:OB RS06255
gene id: 221109:OB_RS06255
uniprot id: Q8ERV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS13875
gene id: 221109:OB_RS13875
uniprot id: Q8EMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

221109:OB RS07255
gene id: 221109:OB_RS07255
uniprot id: Q8ERB5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS16400
gene id: 221109:OB_RS16400
uniprot id: Q8CX62
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

221109:OB RS00450
gene id: 221109:OB_RS00450
uniprot id: Q8EU12
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

221109:OB RS02630
gene id: 221109:OB_RS02630
uniprot id: Q8ESY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

221109:OB RS12730
gene id: 221109:OB_RS12730
uniprot id: Q8ENK3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PpaX family.
messages: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.

221109:OB RS14380
gene id: 221109:OB_RS14380
uniprot id: Q8EMM8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

221109:OB RS10045
gene id: 221109:OB_RS10045
uniprot id: Q8EPY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

221109:OB RS10635
gene id: 221109:OB_RS10635
uniprot id: Q8EPM9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

221109:OB RS03890
gene id: 221109:OB_RS03890
uniprot id: Q8CXK8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

221109:OB RS12690
gene id: 221109:OB_RS12690
uniprot id: Q8ENL1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

221109:OB RS16135
gene id: 221109:OB_RS16135
uniprot id: Q8ELQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

221109:OB RS07745
gene id: 221109:OB_RS07745
uniprot id: Q8CWG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

221109:OB RS00655
gene id: 221109:OB_RS00655
uniprot id: Q8ETZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

221109:OB RS07900
gene id: 221109:OB_RS07900
uniprot id: Q8ER07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

221109:OB RS10845
gene id: 221109:OB_RS10845
uniprot id: Q8EPJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

221109:OB RS08815
gene id: 221109:OB_RS08815
uniprot id: Q8EQJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

221109:OB RS04160
gene id: 221109:OB_RS04160
uniprot id: Q8ES71
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

221109:OB RS14280
gene id: 221109:OB_RS14280
uniprot id: Q8EMP6
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

221109:OB RS08695
gene id: 221109:OB_RS08695
uniprot id: Q8EQL3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

221109:OB RS03295
gene id: 221109:OB_RS03295
uniprot id: Q8ESL3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

221109:OB RS12200
gene id: 221109:OB_RS12200
uniprot id: Q8ENV3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

221109:OB RS15830
gene id: 221109:OB_RS15830
uniprot id: Q8ELV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

221109:OB RS00725
gene id: 221109:OB_RS00725
uniprot id: Q8ETY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

221109:OB RS15255
gene id: 221109:OB_RS15255
uniprot id: Q8EM70
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

221109:OB RS04670
gene id: 221109:OB_RS04670
uniprot id: Q8CV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS16500
gene id: 221109:OB_RS16500
uniprot id: Q8ELI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS00680
gene id: 221109:OB_RS00680
uniprot id: Q8ETZ4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

221109:OB RS02975
gene id: 221109:OB_RS02975
uniprot id: Q8ESR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

221109:OB RS16610
gene id: 221109:OB_RS16610
uniprot id: Q8ELG7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

221109:OB RS08060
gene id: 221109:OB_RS08060
uniprot id: Q8EQY2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

221109:OB RS17370
gene id: 221109:OB_RS17370
uniprot id: Q8EL23
names: Similarity
messages: Belongs to the TPP enzyme family.

221109:OB RS08010
gene id: 221109:OB_RS08010
uniprot id: Q8EQY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

221109:OB RS11960
gene id: 221109:OB_RS11960
uniprot id: Q8CZD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

221109:OB RS08350
gene id: 221109:OB_RS08350
uniprot id: Q8EQS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane
messages: Consists of an N-terminal domain, which is sufficient for the localization to the septal ring and is required for cell division, followed by a linker domain, and a C-terminal domain, which forms the translocation motor involved in chromosome segregation. The C-terminal domain can be further subdivided into alpha, beta and gamma subdomains. The alpha and beta subdomains form the DNA pump, and the gamma subdomain is a regulatory subdomain (By similarity).
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
messages: Homohexamer. Forms a ring that surrounds DNA (By similarity).

221109:OB RS15130
gene id: 221109:OB_RS15130
uniprot id: Q8EM94
names: Similarity
messages: Belongs to the peptidase C40 family.

221109:OB RS09825
gene id: 221109:OB_RS09825
uniprot id: Q8CXD6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

221109:OB RS02920
gene id: 221109:OB_RS02920
uniprot id: Q8ESS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS09020
gene id: 221109:OB_RS09020
uniprot id: Q8EQE9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

221109:OB RS02995
gene id: 221109:OB_RS02995
uniprot id: Q8ESR6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

221109:OB RS11110
gene id: 221109:OB_RS11110
uniprot id: Q8EPE8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

221109:OB RS13375
gene id: 221109:OB_RS13375
uniprot id: Q8EN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS08955
gene id: 221109:OB_RS08955
uniprot id: Q8EQG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

221109:OB RS03070
gene id: 221109:OB_RS03070
uniprot id: Q8ESQ1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

221109:OB RS03580
gene id: 221109:OB_RS03580
uniprot id: Q8ESI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

221109:OB RS08215
gene id: 221109:OB_RS08215
uniprot id: Q8EQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

221109:OB RS10460
gene id: 221109:OB_RS10460
uniprot id: Q8EPQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

221109:OB RS15960
gene id: 221109:OB_RS15960
uniprot id: Q8ELT6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12515
gene id: 221109:OB_RS12515
uniprot id: Q8ENP2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

221109:OB RS07765
gene id: 221109:OB_RS07765
uniprot id: Q8ER33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

221109:OB RS12300
gene id: 221109:OB_RS12300
uniprot id: Q8ENT3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

221109:OB RS00845
gene id: 221109:OB_RS00845
uniprot id: Q8ETW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

221109:OB RS09305
gene id: 221109:OB_RS09305
uniprot id: Q8EQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).

221109:OB RS13340
gene id: 221109:OB_RS13340
uniprot id: Q8EN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

221109:OB RS15300
gene id: 221109:OB_RS15300
uniprot id: Q8EM59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

221109:OB RS10465
gene id: 221109:OB_RS10465
uniprot id: Q8CXC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

221109:OB RS14285
gene id: 221109:OB_RS14285
uniprot id: Q8EMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

221109:OB RS00630
gene id: 221109:OB_RS00630
uniprot id: Q8EU04
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

221109:OB RS15545
gene id: 221109:OB_RS15545
uniprot id: Q8EM13
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

221109:OB RS15995
gene id: 221109:OB_RS15995
uniprot id: Q8ELS9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS17220
gene id: 221109:OB_RS17220
uniprot id: Q8EL52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

221109:OB RS11240
gene id: 221109:OB_RS11240
uniprot id: Q8EPC4
names: Similarity
messages: Belongs to the UPF0173 family.

221109:OB RS11400
gene id: 221109:OB_RS11400
uniprot id: Q8CXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

221109:OB RS14610
gene id: 221109:OB_RS14610
uniprot id: Q8EMI2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

221109:OB RS04585
gene id: 221109:OB_RS04585
uniprot id: Q8CV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

221109:OB RS17035
gene id: 221109:OB_RS17035
uniprot id: Q8EL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

221109:OB RS15815
gene id: 221109:OB_RS15815
uniprot id: Q8ELW2
names: Similarity
messages: Belongs to the WrbA family.

221109:OB RS05535
gene id: 221109:OB_RS05535
uniprot id: Q8CUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

221109:OB RS00065
gene id: 221109:OB_RS00065
uniprot id: Q8EU77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

221109:OB RS02620
gene id: 221109:OB_RS02620
uniprot id: Q8ESY4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

221109:OB RS08155
gene id: 221109:OB_RS08155
uniprot id: Q8EQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

221109:OB RS03340
gene id: 221109:OB_RS03340
uniprot id: Q8ESK5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

221109:OB RS09640
gene id: 221109:OB_RS09640
uniprot id: Q8CXE3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

221109:OB RS17355
gene id: 221109:OB_RS17355
uniprot id: Q8EL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane

221109:OB RS11755
gene id: 221109:OB_RS11755
uniprot id: Q8EP33
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

221109:OB RS06205
gene id: 221109:OB_RS06205
uniprot id: Q8ERW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

221109:OB RS15340
gene id: 221109:OB_RS15340
uniprot id: Q8EM53
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

221109:OB RS04305
gene id: 221109:OB_RS04305
uniprot id: Q8ES40
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12615
gene id: 221109:OB_RS12615
uniprot id: Q8ENM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

221109:OB RS11080
gene id: 221109:OB_RS11080
uniprot id: Q8EPF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

221109:OB RS02985
gene id: 221109:OB_RS02985
uniprot id: Q8ESR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

221109:OB RS01070
gene id: 221109:OB_RS01070
uniprot id: Q8ETS4
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tlp family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

221109:OB RS15140
gene id: 221109:OB_RS15140
uniprot id: Q8EM92
names: Similarity
messages: Belongs to the peptidase S66 family.

221109:OB RS08625
gene id: 221109:OB_RS08625
uniprot id: Q8EQM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

221109:OB RS03595
gene id: 221109:OB_RS03595
uniprot id: Q8CXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

221109:OB RS10935
gene id: 221109:OB_RS10935
uniprot id: Q8EPI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

221109:OB RS04960
gene id: 221109:OB_RS04960
uniprot id: Q8CV36
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

221109:OB RS11270
gene id: 221109:OB_RS11270
uniprot id: Q8EPB7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

221109:OB RS11620
gene id: 221109:OB_RS11620
uniprot id: Q8EP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS14095
gene id: 221109:OB_RS14095
uniprot id: Q8EMT2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

221109:OB RS12500
gene id: 221109:OB_RS12500
uniprot id: P59174
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

221109:OB RS14630
gene id: 221109:OB_RS14630
uniprot id: Q8EMH8
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

221109:OB RS07945
gene id: 221109:OB_RS07945
uniprot id: Q8ER00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

221109:OB RS05405
gene id: 221109:OB_RS05405
uniprot id: Q8CUU6
names: Similarity
messages: Belongs to the KdgT transporter family.

221109:OB RS15930
gene id: 221109:OB_RS15930
uniprot id: Q8CWF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

221109:OB RS10875
gene id: 221109:OB_RS10875
uniprot id: Q8EPJ0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

221109:OB RS08805
gene id: 221109:OB_RS08805
uniprot id: Q8CXG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS12795
gene id: 221109:OB_RS12795
uniprot id: Q8ENJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

221109:OB RS07855
gene id: 221109:OB_RS07855
uniprot id: Q8ER16
names: Similarity
messages: Belongs to the asp23 family.

221109:OB RS14930
gene id: 221109:OB_RS14930
uniprot id: Q8EMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

221109:OB RS13120
gene id: 221109:OB_RS13120
uniprot id: Q8ENC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS13870
gene id: 221109:OB_RS13870
uniprot id: Q8EMX7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

221109:OB RS05440
gene id: 221109:OB_RS05440
uniprot id: Q8CUT8
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS04020
gene id: 221109:OB_RS04020
uniprot id: Q8ES97
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

221109:OB RS01360
gene id: 221109:OB_RS01360
uniprot id: Q8ETN2
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

221109:OB RS08145
gene id: 221109:OB_RS08145
uniprot id: Q8EQW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

221109:OB RS05585
gene id: 221109:OB_RS05585
uniprot id: Q8CUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

221109:OB RS02755
gene id: 221109:OB_RS02755
uniprot id: Q8ESW0
names: Similarity
messages: Belongs to the peptidase C56 family.

221109:OB RS08530
gene id: 221109:OB_RS08530
uniprot id: Q8EQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

221109:OB RS11295
gene id: 221109:OB_RS11295
uniprot id: Q8EPB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

221109:OB RS08435
gene id: 221109:OB_RS08435
uniprot id: Q8CXG6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

221109:OB RS08555
gene id: 221109:OB_RS08555
uniprot id: Q8EQP1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

221109:OB RS09780
gene id: 221109:OB_RS09780
uniprot id: Q8CXE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

221109:OB RS16660
gene id: 221109:OB_RS16660
uniprot id: Q8ELF7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

221109:OB RS10035
gene id: 221109:OB_RS10035
uniprot id: Q8EPY4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

221109:OB RS09745
gene id: 221109:OB_RS09745
uniprot id: Q8EQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

221109:OB RS14110
gene id: 221109:OB_RS14110
uniprot id: Q8EMS9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

221109:OB RS04680
gene id: 221109:OB_RS04680
uniprot id: Q8CV78
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS03790
gene id: 221109:OB_RS03790
uniprot id: Q8ESE3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

221109:OB RS09535
gene id: 221109:OB_RS09535
uniprot id: Q8EQ60
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

221109:OB RS15985
gene id: 221109:OB_RS15985
uniprot id: Q8ELT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

221109:OB RS10945
gene id: 221109:OB_RS10945
uniprot id: Q8EPH9
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07070
gene id: 221109:OB_RS07070
uniprot id: Q8ERF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

221109:OB RS08295
gene id: 221109:OB_RS08295
uniprot id: Q8EQT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

221109:OB RS11050
gene id: 221109:OB_RS11050
uniprot id: Q8EPF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

221109:OB RS00240
gene id: 221109:OB_RS00240
uniprot id: P59079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

221109:OB RS09325
gene id: 221109:OB_RS09325
uniprot id: Q8EQ97
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

221109:OB RS17705
gene id: 221109:OB_RS17705
uniprot id: Q8EKV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

221109:OB RS07830
gene id: 221109:OB_RS07830
uniprot id: Q8ER21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

221109:OB RS00440
gene id: 221109:OB_RS00440
uniprot id: Q8EU14
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

221109:OB RS11430
gene id: 221109:OB_RS11430
uniprot id: Q8EP91
names: Similarity
messages: Belongs to the MotB family.

221109:OB RS02695
gene id: 221109:OB_RS02695
uniprot id: Q8ESX1
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.

221109:OB RS15305
gene id: 221109:OB_RS15305
uniprot id: Q8EM58
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

221109:OB RS08210
gene id: 221109:OB_RS08210
uniprot id: Q8EQV3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

221109:OB RS05815
gene id: 221109:OB_RS05815
uniprot id: Q8CUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

221109:OB RS13415
gene id: 221109:OB_RS13415
uniprot id: Q8EN67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

221109:OB RS00900
gene id: 221109:OB_RS00900
uniprot id: Q8ETV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

221109:OB RS12535
gene id: 221109:OB_RS12535
uniprot id: Q8ENN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

221109:OB RS07545
gene id: 221109:OB_RS07545
uniprot id: Q8ER62
names: Similarity
messages: Belongs to the peptidase S16 family.

221109:OB RS03115
gene id: 221109:OB_RS03115
uniprot id: Q8ESP5
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS17450
gene id: 221109:OB_RS17450
uniprot id: Q8EL07
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

221109:OB RS00610
gene id: 221109:OB_RS00610
uniprot id: Q8EU08
names: Similarity
messages: Belongs to the CtsR family.

221109:OB RS16630
gene id: 221109:OB_RS16630
uniprot id: Q8ELG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

221109:OB RS13000
gene id: 221109:OB_RS13000
uniprot id: Q8ENE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS14000
gene id: 221109:OB_RS14000
uniprot id: Q8EMU9
names: Similarity
messages: Belongs to the UPF0047 family.

221109:OB RS04475
gene id: 221109:OB_RS04475
uniprot id: Q8CZE7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

221109:OB RS13105
gene id: 221109:OB_RS13105
uniprot id: Q8CZD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

221109:OB RS11375
gene id: 221109:OB_RS11375
uniprot id: Q8EP99
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

221109:OB RS04080
gene id: 221109:OB_RS04080
uniprot id: Q8ES86
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS05715
gene id: 221109:OB_RS05715
uniprot id: Q8CUN1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

221109:OB RS14425
gene id: 221109:OB_RS14425
uniprot id: Q8EML9
names: Subcellular Location Annotation
messages: Cell membrane

221109:OB RS01435
gene id: 221109:OB_RS01435
uniprot id: Q8ETL9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

221109:OB RS07145
gene id: 221109:OB_RS07145
uniprot id: Q8ERD8
names: Similarity
messages: Belongs to the UPF0312 family.

221109:OB RS14615
gene id: 221109:OB_RS14615
uniprot id: Q8EMI1
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00715
gene id: 221109:OB_RS00715
uniprot id: Q8ETY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

221109:OB RS06360
gene id: 221109:OB_RS06360
uniprot id: Q8ERT8
names: Similarity
messages: Belongs to the P(II) protein family.

221109:OB RS17770
gene id: 221109:OB_RS17770
uniprot id: Q8EKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

221109:OB RS03685
gene id: 221109:OB_RS03685
uniprot id: Q8ESG4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

221109:OB RS05260
gene id: 221109:OB_RS05260
uniprot id: Q8CUX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS07385
gene id: 221109:OB_RS07385
uniprot id: P59153
names: Similarity
messages: Belongs to the UPF0223 family.

221109:OB RS11135
gene id: 221109:OB_RS11135
uniprot id: Q8EPE3
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS00780
gene id: 221109:OB_RS00780
uniprot id: Q8ETX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

221109:OB RS07935
gene id: 221109:OB_RS07935
uniprot id: Q8ER02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

221109:OB RS14530
gene id: 221109:OB_RS14530
uniprot id: Q8EMJ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

221109:OB RS07755
gene id: 221109:OB_RS07755
uniprot id: Q8ER35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

221109:OB RS00335
gene id: 221109:OB_RS00335
uniprot id: Q8EU30
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS16565
gene id: 221109:OB_RS16565
uniprot id: Q8ELH6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07810
gene id: 221109:OB_RS07810
uniprot id: Q8ER25
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

221109:OB RS09600
gene id: 221109:OB_RS09600
uniprot id: Q8CXE6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

221109:OB RS09495
gene id: 221109:OB_RS09495
uniprot id: Q8EQ67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

221109:OB RS06465
gene id: 221109:OB_RS06465
uniprot id: Q8ERR8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS00405
gene id: 221109:OB_RS00405
uniprot id: Q8EU17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

221109:OB RS02590
gene id: 221109:OB_RS02590
uniprot id: Q8ESZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

221109:OB RS04640
gene id: 221109:OB_RS04640
uniprot id: Q8CV86
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

221109:OB RS12745
gene id: 221109:OB_RS12745
uniprot id: Q8ENK1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

221109:OB RS14435
gene id: 221109:OB_RS14435
uniprot id: Q8EML7
names: Similarity
messages: Belongs to the PspA/IM30 family.

221109:OB RS08130
gene id: 221109:OB_RS08130
uniprot id: Q8EQW8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

221109:OB RS09435
gene id: 221109:OB_RS09435
uniprot id: Q8EQ80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

221109:OB RS11260
gene id: 221109:OB_RS11260
uniprot id: Q8EPB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

221109:OB RS02235
gene id: 221109:OB_RS02235
uniprot id: Q8ET60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS09645
gene id: 221109:OB_RS09645
uniprot id: Q8CXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

221109:OB RS11660
gene id: 221109:OB_RS11660
uniprot id: Q8EP50
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

221109:OB RS11695
gene id: 221109:OB_RS11695
uniprot id: Q8EP43
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

221109:OB RS05640
gene id: 221109:OB_RS05640
uniprot id: Q8CUP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS04005
gene id: 221109:OB_RS04005
uniprot id: Q8ESA0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

221109:OB RS06015
gene id: 221109:OB_RS06015
uniprot id: Q8CUG8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06365
gene id: 221109:OB_RS06365
uniprot id: Q8ERT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

221109:OB RS01695
gene id: 221109:OB_RS01695
uniprot id: Q8ETG9
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-responsive transcriptional regulator.

221109:OB RS15860
gene id: 221109:OB_RS15860
uniprot id: Q8ELV4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

221109:OB RS12530
gene id: 221109:OB_RS12530
uniprot id: Q8ENP0
names: Similarity
messages: Belongs to the sigma-54 factor family.

221109:OB RS02990
gene id: 221109:OB_RS02990
uniprot id: Q8CXM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

221109:OB RS16495
gene id: 221109:OB_RS16495
uniprot id: Q8ELJ0
names: Similarity
messages: Belongs to the TPP enzyme family.

221109:OB RS08405
gene id: 221109:OB_RS08405
uniprot id: Q8EQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

221109:OB RS08545
gene id: 221109:OB_RS08545
uniprot id: Q8EQP3
names: Similarity
messages: Belongs to the glutamine synthetase family.

221109:OB RS11680
gene id: 221109:OB_RS11680
uniprot id: Q8EP46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

221109:OB RS02520
gene id: 221109:OB_RS02520
uniprot id: Q8ET05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

221109:OB RS04230
gene id: 221109:OB_RS04230
uniprot id: Q8ES57
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS04535
gene id: 221109:OB_RS04535
uniprot id: Q8CVA7
names: Similarity
messages: Belongs to the peptidase S58 family.

221109:OB RS17365
gene id: 221109:OB_RS17365
uniprot id: Q8CX56
names: Similarity
messages: Belongs to the glutamate synthase family.

221109:OB RS04120
gene id: 221109:OB_RS04120
uniprot id: Q8ES79
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

221109:OB RS09655
gene id: 221109:OB_RS09655
uniprot id: Q8EQ46
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

221109:OB RS03925
gene id: 221109:OB_RS03925
uniprot id: Q8ESB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

221109:OB RS10330
gene id: 221109:OB_RS10330
uniprot id: Q8EPT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

221109:OB RS16950
gene id: 221109:OB_RS16950
uniprot id: Q8ELA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

221109:OB RS05750
gene id: 221109:OB_RS05750
uniprot id: Q8CUM4
names: Subunit
messages: Homodimer.

221109:OB RS07725
gene id: 221109:OB_RS07725
uniprot id: Q8ER37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

221109:OB RS08075
gene id: 221109:OB_RS08075
uniprot id: Q8EQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

221109:OB RS12085
gene id: 221109:OB_RS12085
uniprot id: Q8ENX4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

221109:OB RS13600
gene id: 221109:OB_RS13600
uniprot id: Q8EN33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS08660
gene id: 221109:OB_RS08660
uniprot id: Q8EQL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

221109:OB RS06060
gene id: 221109:OB_RS06060
uniprot id: Q8CXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

221109:OB RS02880
gene id: 221109:OB_RS02880
uniprot id: Q8CXN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

221109:OB RS15460
gene id: 221109:OB_RS15460
uniprot id: Q8EM29
names: Similarity
messages: Belongs to the acyltransferase 3 family.

221109:OB RS03225
gene id: 221109:OB_RS03225
uniprot id: Q8ESM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS10280
gene id: 221109:OB_RS10280
uniprot id: Q8EPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

221109:OB RS14460
gene id: 221109:OB_RS14460
uniprot id: Q8EML2
names: Similarity
messages: Belongs to the CdaR family.

221109:OB RS10120
gene id: 221109:OB_RS10120
uniprot id: Q8EPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

221109:OB RS11640
gene id: 221109:OB_RS11640
uniprot id: Q8EP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

221109:OB RS11595
gene id: 221109:OB_RS11595
uniprot id: Q8EP61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

221109:OB RS16290
gene id: 221109:OB_RS16290
uniprot id: Q8ELM6
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS10955
gene id: 221109:OB_RS10955
uniprot id: Q8EPH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

221109:OB RS14125
gene id: 221109:OB_RS14125
uniprot id: Q8EMS6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

221109:OB RS08560
gene id: 221109:OB_RS08560
uniprot id: Q8EQP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

221109:OB RS14050
gene id: 221109:OB_RS14050
uniprot id: Q8EMU0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

221109:OB RS11910
gene id: 221109:OB_RS11910
uniprot id: Q8EP04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

221109:OB RS15170
gene id: 221109:OB_RS15170
uniprot id: Q8EM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

221109:OB RS16090
gene id: 221109:OB_RS16090
uniprot id: Q8ELR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS13435
gene id: 221109:OB_RS13435
uniprot id: Q8EN63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

221109:OB RS02020
gene id: 221109:OB_RS02020
uniprot id: Q8ETA2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

221109:OB RS08240
gene id: 221109:OB_RS08240
uniprot id: Q8EQU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).

221109:OB RS04310
gene id: 221109:OB_RS04310
uniprot id: Q8ES39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

221109:OB RS13050
gene id: 221109:OB_RS13050
uniprot id: Q8CX95
names: Similarity
messages: Belongs to the MotB family.

221109:OB RS04210
gene id: 221109:OB_RS04210
uniprot id: Q8ES61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metal hydrolase YfiT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Possible metal-dependent hydrolase.

221109:OB RS06300
gene id: 221109:OB_RS06300
uniprot id: Q8CXK0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

221109:OB RS03930
gene id: 221109:OB_RS03930
uniprot id: Q8ESB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS02580
gene id: 221109:OB_RS02580
uniprot id: Q8ESZ2
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

221109:OB RS11130
gene id: 221109:OB_RS11130
uniprot id: Q8EPE4
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS17255
gene id: 221109:OB_RS17255
uniprot id: Q8EL46
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS06130
gene id: 221109:OB_RS06130
uniprot id: Q8ERY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell membrane
messages: Required for disulfide bond formation in some proteins.

221109:OB RS10545
gene id: 221109:OB_RS10545
uniprot id: Q8EPP4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

221109:OB RS06620
gene id: 221109:OB_RS06620
uniprot id: Q8ERP0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

221109:OB RS13380
gene id: 221109:OB_RS13380
uniprot id: Q8EN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

221109:OB RS00300
gene id: 221109:OB_RS00300
uniprot id: Q8CXP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

221109:OB RS06220
gene id: 221109:OB_RS06220
uniprot id: Q8ERW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

221109:OB RS04490
gene id: 221109:OB_RS04490
uniprot id: Q8ES04
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS12430
gene id: 221109:OB_RS12430
uniprot id: Q8CZD7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

221109:OB RS14900
gene id: 221109:OB_RS14900
uniprot id: Q8EMD3
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

221109:OB RS00465
gene id: 221109:OB_RS00465
uniprot id: Q8EU10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS03565
gene id: 221109:OB_RS03565
uniprot id: Q8ESI5
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS07655
gene id: 221109:OB_RS07655
uniprot id: Q8ER49
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

221109:OB RS07595
gene id: 221109:OB_RS07595
uniprot id: Q8ER52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

221109:OB RS02690
gene id: 221109:OB_RS02690
uniprot id: Q8ESX2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

221109:OB RS02485
gene id: 221109:OB_RS02485
uniprot id: Q8ET12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

221109:OB RS03705
gene id: 221109:OB_RS03705
uniprot id: Q8ESG1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

221109:OB RS00745
gene id: 221109:OB_RS00745
uniprot id: Q8ETY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

221109:OB RS09220
gene id: 221109:OB_RS09220
uniprot id: Q8EQB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.
messages: Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan (By similarity).

221109:OB RS12210
gene id: 221109:OB_RS12210
uniprot id: Q8ENV1
names: Similarity
messages: Belongs to the peptidase S8 family.

221109:OB RS14770
gene id: 221109:OB_RS14770
uniprot id: Q8EMF5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

221109:OB RS11955
gene id: 221109:OB_RS11955
uniprot id: Q8CXA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

221109:OB RS10030
gene id: 221109:OB_RS10030
uniprot id: Q8EPY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

221109:OB RS10905
gene id: 221109:OB_RS10905
uniprot id: Q8CXB3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

221109:OB RS10275
gene id: 221109:OB_RS10275
uniprot id: Q8CXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

221109:OB RS12245
gene id: 221109:OB_RS12245
uniprot id: Q8ENU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

221109:OB RS17800
gene id: 221109:OB_RS17800
uniprot id: Q8EKT9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

221109:OB RS00115
gene id: 221109:OB_RS00115
uniprot id: Q8EU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

221109:OB RS10115
gene id: 221109:OB_RS10115
uniprot id: Q8EPW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

221109:OB RS13810
gene id: 221109:OB_RS13810
uniprot id: Q8EMZ0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

221109:OB RS12015
gene id: 221109:OB_RS12015
uniprot id: Q8ENY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

221109:OB RS00720
gene id: 221109:OB_RS00720
uniprot id: P59165
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Because the enzyme that would modify Asp-102 to 3-methylthioaspartic acid has not been found in the proteome of this organism, that modification is not predicted.
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

221109:OB RS17710
gene id: 221109:OB_RS17710
uniprot id: Q8CX55
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

221109:OB RS15465
gene id: 221109:OB_RS15465
uniprot id: Q8EM28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

221109:OB RS13845
gene id: 221109:OB_RS13845
uniprot id: Q8EMY3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

221109:OB RS11330
gene id: 221109:OB_RS11330
uniprot id: P59130
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

221109:OB RS04440
gene id: 221109:OB_RS04440
uniprot id: Q8ES13
names: Subcellular Location Annotation
messages: Cytoplasm

221109:OB RS09995
gene id: 221109:OB_RS09995
uniprot id: Q8EPZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

221109:OB RS08335
gene id: 221109:OB_RS08335
uniprot id: Q8EQT0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

221109:OB RS15975
gene id: 221109:OB_RS15975
uniprot id: Q8ELT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

221109:OB RS10265
gene id: 221109:OB_RS10265
uniprot id: Q8EPU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

221109:OB RS16690
gene id: 221109:OB_RS16690
uniprot id: Q8ELF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

221109:OB RS06405
gene id: 221109:OB_RS06405
uniprot id: Q8ERS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

221109:OB RS05785
gene id: 221109:OB_RS05785
uniprot id: Q8CUL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

221109:OB RS15845
gene id: 221109:OB_RS15845
uniprot id: Q8ELV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

221109:OB RS00280
gene id: 221109:OB_RS00280
uniprot id: Q8CXQ0
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

221109:OB RS13765
gene id: 221109:OB_RS13765
uniprot id: Q8EMZ9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

221109:OB RS10355
gene id: 221109:OB_RS10355
uniprot id: Q8EPS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

221109:OB RS10530
gene id: 221109:OB_RS10530
uniprot id: Q8EPP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

221109:OB RS13280
gene id: 221109:OB_RS13280
uniprot id: Q8EN94
names: Similarity
messages: Belongs to the CvfB family.

221109:OB RS05135
gene id: 221109:OB_RS05135
uniprot id: Q8CV00
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

221109:OB RS00895
gene id: 221109:OB_RS00895
uniprot id: Q8ETV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

221109:OB RS00830
gene id: 221109:OB_RS00830
uniprot id: P59123
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

221109:OB RS05575
gene id: 221109:OB_RS05575
uniprot id: Q8CUR0
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS15535
gene id: 221109:OB_RS15535
uniprot id: Q8EM15
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

221109:OB RS17775
gene id: 221109:OB_RS17775
uniprot id: Q8CX54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

221109:OB RS09295
gene id: 221109:OB_RS09295
uniprot id: P59106
names: Function
names: Similarity
messages: Belongs to the YpeB family.
messages: Required for spore cortex hydrolysis during germination. Appears to be required for either expression, localization, activation or function of SleB (By similarity).

221109:OB RS15765
gene id: 221109:OB_RS15765
uniprot id: Q8ELX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS16115
gene id: 221109:OB_RS16115
uniprot id: Q8ELQ8
names: Similarity
messages: Belongs to the peptidase S66 family.

221109:OB RS12815
gene id: 221109:OB_RS12815
uniprot id: Q8ENI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

221109:OB RS07585
gene id: 221109:OB_RS07585
uniprot id: Q8ER54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

221109:OB RS02280
gene id: 221109:OB_RS02280
uniprot id: Q8ET51
names: Similarity
messages: Belongs to the AHA1 family.

221109:OB RS17095
gene id: 221109:OB_RS17095
uniprot id: Q8EL75
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

221109:OB RS15240
gene id: 221109:OB_RS15240
uniprot id: Q8EM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

221109:OB RS16030
gene id: 221109:OB_RS16030
uniprot id: Q8ELS3
names: Similarity
messages: Belongs to the peptidase S13 family.

221109:OB RS10005
gene id: 221109:OB_RS10005
uniprot id: Q8EPZ0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

221109:OB RS14190
gene id: 221109:OB_RS14190
uniprot id: Q8EMR3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

221109:OB RS12175
gene id: 221109:OB_RS12175
uniprot id: Q8ENV8
names: Subcellular Location Annotation
messages: Membrane

221109:OB RS01585
gene id: 221109:OB_RS01585
uniprot id: Q8ETJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

221109:OB RS06750
gene id: 221109:OB_RS06750
uniprot id: Q8ERL4
names: Similarity
messages: Belongs to the peptidase S51 family.

221109:OB RS17490
gene id: 221109:OB_RS17490
uniprot id: Q8EKZ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

221109:OB RS11870
gene id: 221109:OB_RS11870
uniprot id: Q8EP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm