Major facilitator superfamily (MFS) profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL15/eL18
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phenol hydroxylase C-terminal dimerisation
FAD-dependent oxidoreductase 2 FAD binding
Resolvase/invertase-type recombinase catalytic
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Sugar fermentation stimulation protein C-terminal
TonB-dependent receptor-like beta-barrel
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Exonuclease VII large subunit C-terminal
Pseudouridine synthase I TruA alpha/beta
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
SGNH hydrolase-type esterase domain-containing protein
Magnesium transporter MgtE intracellular domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Cytochrome b561 bacterial/Ni-hydrogenase
Ribosomal RNA adenine methylase transferase N-terminal
Translation elongation factor P/YeiP central
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Membrane insertase YidC/Oxa/ALB C-terminal
Important for interaction with partner proteins
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
CobB/CobQ-like glutamine amidotransferase
Cobaltochelatase subunit CobS N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
NIF system FeS cluster assembly NifU N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
TRAP C4-dicarboxylate transport system permease DctM subunit
Interaction with polymerase core subunit RpoC
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Penicillin-binding protein transpeptidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar basal body-associated protein FliL
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Flagellar motor switch protein FliN-like C-terminal
Prokaryotic-type class I peptide chain release factors
Polymerase/histidinol phosphatase N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Inner membrane protein YgaP-like transmembrane
Reversibly protonated during proton transport
Cytochrome C biogenesis protein transmembrane
Chromosomal replication initiator DnaA C-terminal
Ribulose bisphosphate carboxylase small subunit
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glucose-methanol-choline oxidoreductase N-terminal
Cob(I)alamin adenosyltransferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Phosphopantothenoylcysteine decarboxylase
Membrane fusion protein biotin-lipoyl like
Glycine cleavage T-protein C-terminal barrel
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
Pyruvate/ketoisovalerate oxidoreductase catalytic
Moybdenum cofactor oxidoreductase dimerisation
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA primase/polymerase bifunctional N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Electron transfer via tryptophanyl radical
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Heme-copper oxidase subunit III family profile
Essential for prephenate dehydratase activity
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
YbaK/aminoacyl-tRNA synthetase-associated
Carbamoyl-phosphate synthase small subunit N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Molybdopterin cofactor biosynthesis C (MoaC)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
RNA polymerase sigma factor 70 region 4 type 2
Aminoacyl-transfer RNA synthetases class-II family profile
Proton acceptor; for glutaminase activity
Activator of Hsp90 ATPase homologue 1-like C-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Prepilin type IV endopeptidase peptidase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glycosyl transferase family 3 N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal
CDP-alcohol phosphatidyltransferase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Survival protein SurE-like phosphatase/nucleotidase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Mannose-6-phosphate isomerase type II C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
SUF system FeS cluster assembly SufBD N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Solute-binding protein family 3/N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Saccharopine dehydrogenase-like C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
N6 adenine-specific DNA methyltransferase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Beta-lactamase hydrolase-like protein phosphatase-like
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
ABC transporter substrate-binding protein PnrA-like
Gamma-butyrobetaine hydroxylase-like N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-97)
ATP synthase F1 complex delta/epsilon subunit N-terminal
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
Flagella basal body P-ring formation protein FlgA
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
ABC-type transport auxiliary lipoprotein component
RND efflux pump membrane fusion protein barrel-sandwich
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
High-affinity zinc uptake system protein ZnuA
UDP N-acetylglucosamine O-acyltransferase C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
RNA 2-O ribose methyltransferase substrate binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Adaptive response protein AidB N-terminal
Terminase large subunit gp17-like C-terminal
Alanyl-transfer RNA synthetases family profile
Ribose-phosphate pyrophosphokinase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
PHA accumulation regulator DNA-binding N-terminal
von Hippel-Lindau disease tumour suppressor beta
von Hippel-Lindau disease tumour suppressor beta domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Transposase IS116/IS110/IS902 C-terminal
Large ribosomal subunit protein uL2 C-terminal
Glycoside hydrolase family 31 N-terminal
Organic solvent tolerance-like N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Transcription factor NikR nickel binding C-terminal
Abortive infection protein-like C-terminal
N-acetylneuraminic acid synthase N-terminal
RNA binding; important for wobble base 34 recognition
Pyruvate phosphate dikinase AMP/ATP-binding
Tat pathway signal sequence domain protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glycosyl hydrolases family 2 sugar binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
Release factor glutamine methyltransferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Cation-transporting P-type ATPase N-terminal
Histidine phosphotransferase ChpT C-terminal
Glycine zipper domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Bacterial type II secretion system protein E
Alpha-D-phosphohexomutase alpha/beta/alpha
L-seryl-tRNA selenium transferase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aspartate/homoserine dehydrogenase NAD-binding
Periplasmic copper-binding protein NosD beta helix
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Sodium/calcium exchanger membrane region
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Cysteine sulfenic acid (-SOH) intermediate
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Endoribonuclease L-PSP/chorismate mutase-like
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
PsrA tetracyclin repressor-like C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Quinohemoprotein amine dehydrogenase gamma subunit structural
Antitoxin Xre/MbcA/ParS-like toxin-binding
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Guanylate kinase/L-type calcium channel beta subunit
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Glucose-methanol-choline oxidoreductase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Bacteriophage tail tape measure C-terminal
Flagellar hook-length control protein-like C-terminal
Outer membrane protein assembly factor BamD
DNA replication/recombination mediator RecO N-terminal
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
tRNA pseudouridylate synthase B C-terminal
Signal recognition particle SRP54 helical bundle
Major facilitator superfamily associated
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
N-end rule aminoacyl transferase C-terminal
Polysaccharide biosynthesis protein C-terminal
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Increases nucleophilicity of active site Cys
Small ribosomal subunit protein uS4 N-terminal
Methionyl-tRNA synthetase anticodon-binding
Chalcone isomerase domain-containing protein
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
DNA mismatch repair proteins mutS family
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Anthranilate synthase component I N-terminal
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Leucine-binding protein domain-containing protein
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Bacterial spore germination immunoglobulin-like domain-containing protein
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal