RNA 2-O ribose methyltransferase substrate binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Copper amine oxidase-like N-terminal domain-containing protein
Thiamine pyrophosphate enzyme TPP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
RND efflux pump membrane fusion protein barrel-sandwich
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Pyruvate/ketoisovalerate oxidoreductase catalytic
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Tryptophan synthase beta chain-like PALP
Choloylglycine hydrolase/NAAA C-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
5-glutamyl coenzyme A thioester intermediate
Flagellar basal-body/hook protein C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Flagellar assembly protein FliH/Type III secretion system HrpE
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Pyridoxamine 5'-phosphate oxidase putative
Resolvase/invertase-type recombinase catalytic
Prepilin type IV endopeptidase peptidase
Shikimate dehydrogenase substrate binding N-terminal
Bacterial type II secretion system protein E
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Major facilitator superfamily (MFS) profile
DNA replication/recombination mediator RecO N-terminal
Alanyl-transfer RNA synthetases family profile
Cell envelope-related transcriptional attenuator
Penicillin-binding protein transpeptidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Exonuclease VII large subunit C-terminal
Sporulation initiation factor Spo0A C-terminal
Flagellar motor switch protein FliN-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Replication-associated protein G2P N-terminal
Inosine/uridine-preferring nucleoside hydrolase
DNA mismatch repair proteins mutS family
Pseudouridine synthase I TruA alpha/beta
Glycosyltransferase subfamily 4-like N-terminal
Bacterial transcription activator effector binding
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyruvate phosphate dikinase AMP/ATP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Membrane insertase YidC/Oxa/ALB C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Important for beta-aspartyl-AMP intermediate formation
RNA binding; important for wobble base 34 recognition
Schiff-base intermediate with acetaldehyde
Aldehyde ferredoxin oxidoreductase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Flagellar basal body rod protein N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Important for interaction with partner proteins
ATP-dependent DNA helicase RecG C-terminal
Transposase IS116/IS110/IS902 C-terminal
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
O-(5'-phospho-DNA)-tyrosine intermediate
Cation-transporting P-type ATPase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Helicase superfamily 3 single-stranded DNA/RNA virus
Anthranilate synthase component I N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Plays an important role in substrate specificity
Lysidine-tRNA(Ile) synthetase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
RNA polymerase sigma factor 70 region 4 type 2
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Ribosomal RNA adenine methylase transferase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Sporulation transcription regulator WhiA N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Could play a key role in the communication between the regulatory and the substrate sites
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Na+-translocating membrane potential-generating system MpsC
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Solute-binding protein family 3/N-terminal
Saccharopine dehydrogenase-like C-terminal
Large ribosomal subunit protein uL2 C-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Glycine cleavage T-protein C-terminal barrel
Polysaccharide biosynthesis protein C-terminal
Thiamin pyrophosphokinase thiamin-binding
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Carbohydrate-binding domain-containing protein
Important for autoinhibition of adenylyltransferase activity
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
ABC transporter substrate-binding protein PnrA-like
Interaction with polymerase core subunit RpoC
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Glycosyl transferase family 3 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sporulation stage II protein D amidase enhancer LytB N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Sporulation stage IV protein A C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Flagellar hook-length control protein-like C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
tRNA pseudouridylate synthase B C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Prokaryotic-type class I peptide chain release factors
Dipicolinate synthase subunit A N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Dinitrogenase iron-molybdenum cofactor biosynthesis
DNA-directed RNA polymerase RpoA/D/Rpb3-type
D-galactarate/Altronate dehydratase C-terminal
Membrane fusion protein biotin-lipoyl like
Molybdopterin cofactor biosynthesis C (MoaC)
Ionotropic glutamate receptor C-terminal
Release factor glutamine methyltransferase N-terminal
DNA-directed DNA polymerase family A palm
Pyrimidine nucleoside phosphorylase C-terminal
Phosphoribosylformylglycinamidine synthase linker
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Tryptophan RNA-binding attenuator protein
Transcriptional coactivator p15 (PC4) C-terminal
ABC-type glycine betaine transport system substrate-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glycosyl hydrolase-like 10 domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL15/eL18
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Translation elongation factor P/YeiP central
Bacterial Ig-like domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Threonine/serine exporter-like N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phosphodiester glycosidase domain-containing protein
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Essential for prephenate dehydratase activity
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding