NADH:ubiquinone oxidoreductase-like 20kDa subunit
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
TonB-dependent receptor-like beta-barrel
RND efflux pump membrane fusion protein barrel-sandwich
Reversibly protonated during proton transport
Disulphide bond isomerase DsbC/G N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Penicillin-binding protein transpeptidase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Could play a key role in the communication between the regulatory and the substrate sites
Major facilitator superfamily associated
Thymidylate synthase/dCMP hydroxymethylase
Formate-dependent nitrite reductase complex subunit
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
DNA polymerase III subunit delta C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Type VI secretion system IcmF C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like stalk
Plays an important role in substrate specificity
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Essential for prephenate dehydratase activity
Solute-binding protein family 3/N-terminal
Major facilitator superfamily (MFS) profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aminoacyl-transfer RNA synthetases class-II family profile
Required for zinc-mediated homotetramerization and catalytic activity
Involved in allosteric activation by GTP
Pyruvate dehydrogenase E1 component middle
Interaction with polymerase core subunit RpoC
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cysteine sulfenic acid (-SOH) intermediate
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RNA binding; important for wobble base 34 recognition
Calcium/calmodulin-dependent protein kinase II association-domain
Glutathionylspermidine synthase pre-ATP-grasp-like
Involved in proton transfer during cleavage
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
D-galactose/methyl-galactoside binding periplasmic protein MglB
UDP N-acetylglucosamine O-acyltransferase C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Alpha-D-phosphohexomutase alpha/beta/alpha
Anthranilate synthase component I N-terminal
Membrane-bound lytic murein transglycosylase A
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Tryptophan synthase beta chain-like PALP
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Phosphocysteine intermediate; for EIIB activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Exonuclease VII large subunit C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Outer membrane protein assembly factor BamC
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Bacterial type II secretion system protein E
Prokaryotic-type class I peptide chain release factors
Required for dimer formation and molybdate binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein bL25 L25
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Mechanosensitive ion channel inner membrane
Ribose-phosphate pyrophosphokinase N-terminal
Chromosomal replication initiator protein DnaA
Peptidoglycan recognition protein family
Bifunctional riboflavin kinase/FMN adenylyltransferase
DNA polymerase III delta subunit C-terminal
Glycosyl transferase family 3 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Transferrin-binding protein B C-lobe/N-lobe beta barrel
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Membrane fusion protein biotin-lipoyl like
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Ribosomal RNA adenine methylase transferase N-terminal
Trimeric autotransporter adhesin YadA-like head
ATP synthase F1 complex delta/epsilon subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Cytochrome C biogenesis protein transmembrane
Carboxypeptidase regulatory-like domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Outer membrane protein assembly factor BamA
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein uL15/eL18
Glucosamine/galactosamine-6-phosphate isomerase
Phosphotransferase system enzyme I N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Pseudouridine synthase I TruA alpha/beta
RNA 2-O ribose methyltransferase substrate binding
Periplasmic nitrate reductase, electron transfer subunit
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Helix-hairpin-helix DNA-binding motif class 1
O-(phosphoribosyl dephospho-coenzyme A)serine
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
High-affinity zinc uptake system protein ZnuA
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Membrane iron-sulfur containing protein FtrD-like
Interacts with tRNA; defines subfamily-specific binding signature
NIF system FeS cluster assembly NifU C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Prepilin type IV endopeptidase peptidase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Positions MEP for the nucleophilic attack
Sugar fermentation stimulation protein C-terminal
Polymerase/histidinol phosphatase N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Important for substrate binding and specificity
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Menaquinone biosynthesis protein MenD middle
Membrane insertase YidC/Oxa/ALB C-terminal
Outer-membrane lipoprotein carrier protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Integral membrane protein YccS N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
6-phosphogluconate dehydrogenase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Ribonucleotide reductase large subunit C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Chalcone isomerase domain-containing protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Chromosomal replication initiator DnaA C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Phosphomannose isomerase type I catalytic
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Ionotropic glutamate receptor C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Outer membrane protein assembly factor BamD
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Threonine/serine exporter-like N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Endolytic peptidoglycan transglycosylase RlpA
Tellurite resistance methyltransferase TehB-like
O-(3'-phospho-DNA)-tyrosine intermediate
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Type I restriction modification DNA specificity
Glycoside-hydrolase family GH114 TIM-barrel
Putative Flp pilus-assembly TadG-like N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Gly-cisPro motif, important for rejection of L-amino acids
Large ribosomal subunit protein uL2 C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Outer membrane protein assembly factor BamE
Appears to be important in orienting the phosphate for catalysis
Lytic transglycosylase superhelical linker
Alpha-glycerophosphate oxidase C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Translation elongation factor P/YeiP central
Important for interaction with partner proteins
Schiff-base intermediate with acetaldehyde
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
N6 adenine-specific DNA methyltransferase N-terminal
Release factor glutamine methyltransferase N-terminal
Alanyl-transfer RNA synthetases family profile
Superoxide dismutase copper/zinc binding
L-seryl-tRNA selenium transferase N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity