Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Potassium channel voltage dependent KCNQ C-terminal
G-protein coupled receptors family 1 profile
Sphingolipid delta4-desaturase N-terminal
Doublesex and mab-3 related transcription factor 3
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4E
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Prokaryotic-type class I peptide chain release factors
Neurotransmitter-gated ion-channel ligand-binding
Neurotransmitter-gated ion-channel transmembrane
Ribosomal RNA-processing protein 7 C-terminal
Tryptophan synthase beta chain-like PALP
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Secreted seminal-vesicle Ly-6 protein 1-like
Sodium/hydrogen exchanger regulatory region
Janus kinase and microtubule-interacting protein C-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Folate receptor-like domain-containing protein
Receptor-binding cancer antigen expressed on SiSo cells
NAD(P)(+)--arginine ADP-ribosyltransferase
Potassium channel tetramerisation-type BTB
Mitochondrial apoptosis-inducing factor C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Peptidase S9 prolyl oligopeptidase catalytic
Spindle assembly abnormal protein 6 N-terminal
Large ribosomal subunit protein uL15/eL18
Nucleolus and neural progenitor protein-like N-terminal
Heme-copper oxidase subunit III family profile
Methyl-CpG binding protein 2/3 C-terminal
Lipocalin/cytosolic fatty-acid binding domain-containing protein
G-protein coupled receptors family 3 profile
Important for interaction with phosphotyrosine-binding proteins
Essential for stabilizing binding to COTL1
5-glutamyl coenzyme A thioester intermediate
Glycine cleavage T-protein C-terminal barrel
Ionotropic glutamate receptor C-terminal
Ionotropic glutamate receptor L-glutamate and glycine-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Serine/threonine-protein kinase receptor
Major facilitator superfamily (MFS) profile
Important for obstruction of the ion pore in the closed conformation
SAM-dependent methyltransferase TRM5/TYW2-type
Translin-associated factor X-interacting protein 1 N-terminal
Cationic amino acid transporter C-terminal
Chemokine interleukin-8-like domain-containing protein
T-cell-specific surface glycoprotein CD28
Cytoplasmic activation/proliferation-associated protein-1 C term
Exocyst complex component Sec3 PIP2-binding N-terminal
Voltage-gated hydrogen channel 1 C-terminal membrane-localisation
G protein-regulated inducer of neurite outgrowth C-terminal
Abscisic acid G-protein coupled receptor-like
Transcription factor CBF/NF-Y/archaeal histone
A-kinase anchor protein 7 RI-RII subunit-binding
A-kinase anchor protein 7-like phosphoesterase
Gamma-butyrobetaine hydroxylase-like N-terminal
Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site
Ribosomal RNA adenine methylase transferase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Major intrinsically disordered Notch2-binding receptor 1-like C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Ribosomal RNA methyltransferase SPB1-like C-terminal
Essential for interaction with SGTA and TTC1
Essential for interaction with SMYD3, TSC1 and STIP1/HOP
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Pyrroline-5-carboxylate reductase catalytic N-terminal
Telomeric single stranded DNA binding POT1/Cdc13
Trafficking kinesin-binding protein C-terminal
Significantly decreased binding to agonist CpG-DNA.
Actin, cytoplasmic 1, N-terminally processed
N-acetylaspartate; in Actin, cytoplasmic 1, N-terminally processed
Telomerase activating protein Est1-like N-terminal
Neuroblastoma-amplified sequence N-terminal
Pre-mRNA processing factor 4 (PRP4)-like
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
Helical; Signal-anchor for type II membrane protein
O-linked (GalNAc...) serine; in soluble form
O-linked (Xyl...) (chondroitin sulfate) serine
Beta-hexosaminidase eukaryotic type N-terminal
Sodium:neurotransmitter symporter serotonin N-terminal
Exocyst complex subunit Exo70 C-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Pre-mRNA cleavage complex subunit Clp1 C-terminal
Retinoblastoma-associated protein C-terminal
Retinoblastoma-associated protein N-terminal
Bicarbonate transporter-like transmembrane
Inward rectifier potassium channel C-terminal
Potassium channel inwardly rectifying Kir N-terminal
Potassium channel inwardly rectifying transmembrane
Lipid-binding serum glycoprotein C-terminal
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
Golgi associated RAB2 interactor protein-like Rab2B-binding
Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium
Peptidoglycan recognition protein family
Family with sequence similarity 209 member B
Calcium-activated potassium channel BK alpha subunit
Aminoacyl-transfer RNA synthetases class-II family profile
SAPK-interacting protein 1 Pleckstrin-homology
MHC class I-like antigen recognition-like
MHC class I-like antigen recognition-like domain-containing protein
U2A'/phosphoprotein 32 family A C-terminal
S100/CaBP-9k-type calcium binding subdomain
Nuclear receptor-binding factor 2 C-terminal
Sodium/calcium exchanger membrane region
Sodium/calcium exchanger membrane region domain-containing protein
Beta-adaptin appendage C-terminal subdomain
Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain
DRY motif; important for ligand-induced conformation changes and signaling
Important for species-specific agonist sensitivity
NPxxY motif; important for ligand-induced conformation changes and signaling
Peptidase M1 membrane alanine aminopeptidase
T-cell surface glycoprotein CD3 zeta chain
DNA mismatch repair proteins mutS family
G-protein coupled receptors family 2 profile 1
G-protein coupled receptors family 2 profile 2
Non-structural maintenance of chromosome element 4 C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
4-carboxyglutamate; in a patient with Moyamoya disease
Conserved oligomeric Golgi complex subunit 4
Dendritic cell-specific transmembrane protein-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Microsomal triglyceride transfer protein large subunit
Tumor necrosis factor receptor superfamily member 11B
G2 and S phase-expressed protein 1 N-terminal
Basic helix-loop-helix ARNT-like protein 1
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO); alternate
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2 and SUMO3)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate
Cation-transporting P-type ATPase N-terminal
Type I cytokine receptor cytokine-binding
Peroxisome membrane anchor protein Pex14p N-terminal
Chromatin assembly factor 1 subunit B C-terminal
Transforming acidic coiled-coil-containing protein C-terminal
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Biopterin-dependent aromatic amino acid hydroxylase family profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
YbaK/aminoacyl-tRNA synthetase-associated
Interleukin-1 receptor antagonist protein
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate
Interacts with SPRY1, SPRY2, SPRY3 and SPRY4
Schiff-base intermediate with substrate; via topaquinone
Centromere protein Cenp-F leucine-rich repeat-containing
Kinetochore protein Cenp-F/LEK1 Rb protein-binding
Origin recognition complex subunit 5 C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
GPI ethanolamine phosphate transferase 1 C-terminal
Carnitine O-palmitoyltransferase 1, liver isoform
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cholesterol side-chain cleavage enzyme, mitochondrial
Glycoside hydrolase family 31 N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Lens epithelium-derived growth factor integrase-binding
O-linked (Xyl...) (glycosaminoglycan) serine
Chromosome segregation protein Spc25 C-terminal
Adenomatous polyposis coli N-terminal dimerisation
Adenomatous polyposis coli protein basic
Transmembrane protein TMEM132 C-terminal
Ferritin heavy chain, N-terminally processed
N-acetylthreonine; in Ferritin heavy chain, N-terminally processed
Sodium channel modifier 1 acidic C-terminal
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Anaphase-promoting complex subunit 4-like WD40
Large ribosomal subunit protein mL46 N-terminal
Prostate tumor-overexpressed gene 1 protein
Large ribosomal subunit protein uL2 C-terminal
Spermatogenesis-associated protein 6 N-terminal
Cysteine sulfonic acid (-SO3H); alternate
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-?)
HTH CENPB-type domain-containing protein
Phosphatidylinositol-glycan-specific phospholipase D
Transducer of regulated CREB activity C-terminal
Transducer of regulated CREB activity N-terminal
Transducer of regulated CREB activity middle
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
Fibronectin type-II domain-containing protein
Exocyst complex subunit Sec15 C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Nuclear receptor-interacting protein 1 repression
Large ribosomal subunit protein uL6 N-terminal
Superoxide dismutase copper/zinc binding
Actin interacting protein 3-like C-terminal
Translocon-associated protein subunit beta
Translation initiation factor beta propellor-like
Chromosome segregation in meiosis protein 3
Zinc finger protein 750-like zinc finger
Parathyroid hormone/parathyroid hormone-related peptide receptor
Arginine vasopressin-induced protein 1/transcriptional and immune response regulator
FACT complex subunit Spt16 N-terminal lobe
Histone chaperone RTT106/FACT complex subunit SPT16-like middle
Copper type II ascorbate-dependent monooxygenase C-terminal
Copper type II ascorbate-dependent monooxygenase N-terminal
RNA polymerase III subunit RPC82-related helix-turn-helix
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
80% loss of P-nitrophenyl acetate hydrolysis activity.
Glycylpeptide N-tetradecanoyltransferase C-terminal
Glycylpeptide N-tetradecanoyltransferase N-terminal
DRY motif; important for ligand-induced conformation changes
Important for inhibition by tetrodotoxin
Important for rapid channel inactivation
In HYPP; found in a Quarter Horse lineage segregating the disease.
Interchain; with the conotoxin GVIIJ (when the channel is not linked to SCN2B or SCN4B; the bond to SCN2B or SCN4B protects the channel from the inhibition by toxin)
Sodium channel protein type 4 subunit alpha
Large ribosomal subunit protein uL10-like insertion
Ubiquitin-like modifier-activating enzyme Atg7 N-terminal
Deubiquitinating enzyme MINDY-3/4 conserved
Nascent polypeptide-associated complex subunit alpha-like UBA
DNA polymerase alpha subunit B N-terminal
DNA polymerase alpha/delta/epsilon subunit B
Intercellular adhesion molecule N-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Platelet-derived growth factor (PDGF) family profile
Large ribosomal subunit protein uL6 alpha-beta
Helical; Anchor for type IV membrane protein
Interaction with membrane phospholipid headgroups
3 X 7 AA tandem repeats of H-R-P-[QL]-[AVP]-P-G
Small ribosomal subunit protein uS2 C-terminal
Translation elongation factor EFTs/EF1B dimerisation
Tartrate-resistant acid phosphatase type 5
Large ribosomal subunit protein uL23 N-terminal
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Inositol polyphosphate-related phosphatase
Interaction with phosphoserine on interacting protein
ABC-type uncharacterised transport system
Nuclear localization signal, and interaction with Tat-TAR RNA
Schwannomin interacting protein 1 C-terminal
Small ribosomal subunit protein uS4 N-terminal
Lymphocyte antigen 6 complex locus protein G6d
5-glutamyl glycerylphosphorylethanolamine
N6,N6,N6-trimethyllysine; alternate; by EEF1AKMT3
N6,N6-dimethyllysine; alternate; by EEF1AKMT3
N6-methyllysine; alternate; by EEF1AKMT3
Aldo-keto reductase family 1 member C23-like protein
RecQ mediated genome instability protein 1-like N-terminal helical
Serine/threonine specific protein phosphatases
G-protein coupled receptors family 3 profile domain-containing protein
Tumor necrosis factor receptor superfamily member 5
Solute carrier family 2, facilitated glucose transporter member 5
Large ribosomal subunit protein uL18 C-terminal eukaryotes
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
MHC class II-associated invariant chain trimerisation
MHC class II-associated invariant chain/CLIP MHC II-interacting
BLOC-1-related complex subunit 6 C-terminal helix
Thioredoxin domain-containing protein 12
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
Lutropin/choriogonadotropin subunit beta
Pulmonary surfactant-associated protein A
Dynein regulatory complex protein 1/2 N-terminal
Immunoglobulin V-set domain-containing protein
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Polypeptide N-acetylgalactosaminyltransferase
Interferon-induced GTP-binding protein Mx1
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Interchain (between beta and alpha chains)
Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal
N-linked (GlcNAc...) asparagine; partial
RNA 2-O ribose methyltransferase substrate binding
Centrosomal protein Cep63/Deup1 N-terminal
Calcitonin gene-related peptide type 1 receptor
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL30 N-terminal eukaryotes
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Gfo/Idh/MocA-like oxidoreductase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Endothelial cell-specific chemotaxis regulator
Homologous-pairing protein 2 winged helix
Modulating (transactivation AF-1); mediates interaction with MACROD1
Tumour necrosis factor receptor 13C TALL-1 binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
ER membrane protein complex subunit 1 C-terminal
Interferon-related developmental regulator C-terminal
Interferon-related developmental regulator N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Superoxide dismutase [Mn], mitochondrial
PiggyBac transposable element-derived protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Potassium voltage-gated channel subfamily D member 2
A kinase-anchoring proteins AKAP-5 and AKAP-12 calmodulin (CaM)-binding
Histone deacetylase complex subunit SAP130 C-terminal
Cleavage stimulation factor subunit 1 dimerisation
Phosphatidylinositol-specific phospholipase C X
N-linked (GlcNAc...) (complex) asparagine
T-cell surface glycoprotein CD8 alpha chain
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Putative WW-binding domain-containing protein
Alpha galactosidase A C-terminal beta-sandwich
Interaction with galactose moiety of substrate glycoprotein
Steroid transmembrane transporter SLC22A24
Ran-GTPase activating protein 1 C-terminal
E3 ubiquitin-protein ligase Arkadia N-terminal
Spo11/DNA topoisomerase VI subunit A N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-?)
With pyrrolidone carboxylic acid at Gln-163.
With pyrrolidone carboxylic acid at Gln-26, isoform lacking 52-WK-53.
Transcription initiation factor IIA gamma subunit C-terminal
Transcription initiation factor IIA gamma subunit N-terminal
ATP-dependent 6-phosphofructokinase, muscle type
DNA polymerase epsilon catalytic subunit A C-terminal
Interchain (with C-99 in IL12A and C-76 in IL23A)
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Rad21/Rec8-like protein C-terminal eukaryotic
Ancestral coatomer element 1 Sec16/Sec31
N6,N6,N6-trimethyllysine; by METTL21A; in vitro
26S proteasome regulatory subunit RPN2 C-terminal
Hyaluronan and proteoglycan link protein 1
Elongation factor 1 beta central acidic region eukaryote
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Tyrosine aminotransferase ubiquitination region
Steroidogenic acute regulatory protein, mitochondrial
Cleavage/polyadenylation specificity factor A subunit C-terminal
Cleavage/polyadenylation specificity factor A subunit N-terminal
Cystic fibrosis transmembrane conductance regulator
dolichyl-phosphate-mannose--protein mannosyltransferase
FLYWCH-type zinc finger-containing protein N-terminal
Calcium-activated chloride channel regulator 1
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
DBC1/CARP1 catalytically inactive NUDIX hydrolase
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
BMP and activin membrane-bound inhibitor C-terminal
BMP and activin membrane-bound inhibitor N-terminal
BMP and activin membrane-bound inhibitor homolog
Helix-hairpin-helix DNA-binding motif class 1
GPI ethanolamine phosphate transferase 2 C-terminal
Granulocyte-macrophage colony-stimulating factor
Asymmetric dimethylarginine; by CARM1; alternate
KH domain-containing RNA-binding protein QKI
Qua1 domain; involved in homodimerization
Insulin-like growth factor-binding protein 5
Nuclear respiratory factor 1 NLS/DNA-binding dimerisation
Chromodomain-helicase-DNA-binding protein 1-like C-terminal
Eukaryotic translation initiation factor 3 subunit E N-terminal
Beta-1,3-galactosyltransferase 2 N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Endoribonuclease Regnase 1/ZC3H12 C-terminal
Immunoglobulin subtype domain-containing protein
Required for complex formation with BFSP1 and BFSP2
Domain of unknown function with conserved HDNR motif
Interchain (with C-1359 or C-1384 in LTBP1); in inactive form
Associated with the impaired acrosomal reaction phenotype.
Inactive peptidyl-prolyl cis-trans isomerase FKBP6
Clathrin/coatomer adaptor adaptin-like N-terminal
Coatomer beta subunit appendage platform
Important for degradation of atrial natriuretic peptide by IDE
SUMO-activating enzyme subunit 2 C-terminal
Ubiquitin/SUMO-activating enzyme ubiquitin-like
Steroid 17-alpha-hydroxylase/17,20 lyase
cGMP-dependent protein kinase interacting
CBF1-interacting co-repressor CIR N-terminal
Insulin-like growth factor-binding protein 1
DNA replication complex GINS protein SLD5 C-terminal
Histone deacetylase glutamine rich N-terminal
Essential for protaglandin-E synthase activity
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Dephosphorylated. The measured range is 16-109.
Dephosphorylated. The measured range is 16-241.
Phosphoserine; in form 4-P, form 5-P, form 6-P and form 7-P
Phosphoserine; in form 5-P, form 6-P and form 7-P
Phosphothreonine; in form 6-P and form 7-P