NADH:flavin oxidoreductase/NADH oxidase N-terminal
Plays an important role in discriminating NADH against NADPH
Chromosomal replication initiator protein DnaA
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Hypersensitivity response secretion-like HrpJ
Aminoacyl-transfer RNA synthetases class-II family profile
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Schiff-base intermediate with substrate; via pyruvic acid
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Outer-membrane lipoprotein carrier protein
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
DNA mismatch repair proteins mutS family
RNA polymerase sigma factor 70 region 4 type 2
Glycine cleavage T-protein C-terminal barrel
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Major facilitator superfamily (MFS) profile
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Phosphatidylinositol-specific phospholipase C X
Polysaccharide biosynthesis protein CapD-like
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Flagellar hook-length control protein-like C-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
RNA binding; important for wobble base 34 recognition
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Bacterial type II secretion system protein E
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
TonB-dependent receptor-like beta-barrel
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Membrane fusion protein biotin-lipoyl like
ABC-type transport auxiliary lipoprotein component domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Gp5/Type VI secretion system Vgr protein OB-fold
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Electron transfer via tryptophanyl radical
Chromosomal replication initiator DnaA C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Flagellar motor switch protein FliN-like C-terminal
Polypeptide-transport-associated ShlB-type
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Gamma-butyrobetaine hydroxylase-like N-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptide methionine sulphoxide reductase MsrA
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Heme-copper oxidase subunit III family profile
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Putative regulatory protein FmdB Zinc ribbon
NAD(P) transhydrogenase alpha subunit C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Phosphotransferase system enzyme I N-terminal
DNA-directed DNA polymerase family A palm
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Bacterial collagen-like protein middle domain-containing protein
Tryptophan synthase beta chain-like PALP
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alanyl-transfer RNA synthetases family profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phosphatidic acid phosphatase type 2/haloperoxidase
Anthranilate synthase component I N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
PHA accumulation regulator DNA-binding N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Prokaryotic-type class I peptide chain release factors
O-(5'-phospho-DNA)-tyrosine intermediate
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Mannose-6-phosphate isomerase type II C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Transcription elongation factor GreA/GreB N-terminal
Pseudouridine synthase I TruA alpha/beta
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Large ribosomal subunit protein uL2 C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Lytic transglycosylase superhelical linker
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glucose-methanol-choline oxidoreductase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Molybdenum ABC transporter substrate-binding protein
Glucose-methanol-choline oxidoreductase C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Exonuclease VII large subunit C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Contractile injection system tube protein N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
DNA replication/recombination mediator RecO N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alpha-D-phosphohexomutase alpha/beta/alpha
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Membrane insertase YidC/Oxa/ALB C-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
UDP N-acetylglucosamine O-acyltransferase C-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Polysaccharide biosynthesis protein C-terminal
Glycosyl transferase family 3 N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Outer membrane protein assembly factor BamD
Cation-transporting P-type ATPase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Carbamoyl-phosphate synthase small subunit N-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Pyruvate phosphate dikinase AMP/ATP-binding
Polymerase/histidinol phosphatase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Interaction with polymerase core subunit RpoC
Type II secretion system protein GspG C-terminal
Adaptive response protein AidB N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Flagellar assembly protein FliH/Type III secretion system HrpE
Carboxypeptidase regulatory-like domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
ABC-type glycine betaine transport system substrate-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Guanylate kinase/L-type calcium channel beta subunit
Phosphoadenosine phosphosulphate reductase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Translation elongation factor P/YeiP central
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
YbaK/aminoacyl-tRNA synthetase-associated
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Small-conductance mechanosensitive channel
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Chalcone isomerase domain-containing protein
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Pyruvate dehydrogenase E1 component middle
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
CobB/CobQ-like glutamine amidotransferase
Saccharopine dehydrogenase-like C-terminal
HicB-like antitoxin of toxin-antitoxin system
Glucan biosynthesis periplasmic MdoG C-terminal
Plays an important role in substrate specificity
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Secretion system X translation initiation factor
Microcin J25-processing protein McjB C-terminal
Cobaltochelatase subunit CobS N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Aspartate/homoserine dehydrogenase NAD-binding
Reversibly protonated during proton transport
Important for interaction with partner proteins
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Flavocytochrome c sulphide dehydrogenase flavin-binding
Proline utilization A proline dehydrogenase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Prepilin type IV endopeptidase peptidase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
RNA 2-O ribose methyltransferase substrate binding
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cysteine sulfenic acid (-SOH) intermediate
Required for zinc-mediated homotetramerization and catalytic activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Endoribonuclease L-PSP/chorismate mutase-like
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Survival protein SurE-like phosphatase/nucleotidase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL15/eL18
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Ribosomal RNA adenine methylase transferase N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Release factor glutamine methyltransferase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Activator of Hsp90 ATPase homologue 1-like C-terminal
Terminase large subunit gp17-like C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Choloylglycine hydrolase/NAAA C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Moybdenum cofactor oxidoreductase dimerisation
Thymidylate synthase/dCMP hydroxymethylase
Quercetin 2,3-dioxygenase C-terminal cupin
Ribonucleotide reductase large subunit C-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
DNA polymerase III subunit delta C-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Integral membrane protein YccS N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Helix-hairpin-helix DNA-binding motif class 1
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Transposase IS116/IS110/IS902 C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Transferrin-binding protein B C-lobe/N-lobe beta barrel domain-containing protein