Major facilitator superfamily (MFS) profile
DNA polymerase III subunit delta C-terminal
Prepilin type IV endopeptidase peptidase
Polypeptide-transport-associated ShlB-type
Large ribosomal subunit protein uL2 C-terminal
Chromosomal replication initiator protein DnaA
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Glucose-methanol-choline oxidoreductase N-terminal
Chalcone isomerase domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Sodium/calcium exchanger membrane region
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Lytic transglycosylase superhelical linker
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
RNA binding; important for wobble base 34 recognition
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
NIF system FeS cluster assembly NifU N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Penicillin-binding protein transpeptidase
CNP1-like uncharacterized domain-containing protein
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
DNA-directed DNA polymerase family A palm
Phosphatidic acid phosphatase type 2/haloperoxidase
Transposase IS204/IS1001/IS1096/IS1165 DDE
Membrane fusion protein biotin-lipoyl like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Saccharopine dehydrogenase-like C-terminal
Pyruvate dehydrogenase E1 component middle
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial type II secretion system protein E
Alpha-D-phosphohexomutase alpha/beta/alpha
Phosphotransferase system enzyme I N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Flagellar assembly protein FliH/Type III secretion system HrpE
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Important for interaction with partner proteins
Plays an important role in discriminating NADH against NADPH
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Prokaryotic-type class I peptide chain release factors
HicB-like antitoxin of toxin-antitoxin system
Aspartate/homoserine dehydrogenase NAD-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Interaction with polymerase core subunit RpoC
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Heme-copper oxidase subunit III family profile
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Small ribosomal subunit protein uS4 N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Membrane insertase YidC/Oxa/ALB C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
S-adenosyl-L-homocysteine hydrolase NAD binding
Histidine-specific methyltransferase SAM-dependent
Nitrite/Sulfite reductase ferredoxin-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Bacterial bifunctional deaminase-reductase C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
PHA accumulation regulator DNA-binding N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
NADH:ubiquinone oxidoreductase 30kDa subunit
Molybdopterin cofactor biosynthesis C (MoaC)
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
N-end rule aminoacyl transferase C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Carbamoyl-phosphate synthase small subunit N-terminal
Tryptophan synthase beta chain-like PALP
Outer membrane protein assembly factor BamD
Aminoacyl-transfer RNA synthetases class-II family profile
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Moybdenum cofactor oxidoreductase dimerisation
Alpha-glycerophosphate oxidase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Gamma-butyrobetaine hydroxylase-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Polysaccharide biosynthesis protein C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
RND efflux pump membrane fusion protein barrel-sandwich
ATP synthase F1 complex delta/epsilon subunit N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL6 alpha-beta
Pyruvate phosphate dikinase AMP/ATP-binding
Survival protein SurE-like phosphatase/nucleotidase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Schiff-base intermediate with substrate; via pyruvic acid
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pyridoxamine 5'-phosphate oxidase putative
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein uL15/eL18
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glucosamine/galactosamine-6-phosphate isomerase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cob(I)alamin adenosyltransferase N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Gly-cisPro motif, important for rejection of L-amino acids
Cysteine sulfenic acid (-SOH) intermediate
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribose-phosphate pyrophosphokinase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Outer-membrane lipoprotein carrier protein
Proline utilization A proline dehydrogenase N-terminal
Translation elongation factor P/YeiP central
Anthranilate synthase component I N-terminal
PilX/PilW C-terminal domain-containing protein
Reversibly protonated during proton transport
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
NADH:ubiquinone oxidoreductase-like 20kDa subunit