Important for interaction with partner proteins
NIF system FeS cluster assembly NifU C-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Flavocytochrome c sulphide dehydrogenase flavin-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Polysaccharide biosynthesis protein CapD-like
Cation-transporting P-type ATPase N-terminal
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein uL6 alpha-beta
TonB-dependent receptor-like beta-barrel
6-hydroxymethylpterin diphosphokinase MptE-like
Penicillin-binding protein transpeptidase
Saccharopine dehydrogenase-like C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Mannose-6-phosphate isomerase type II C-terminal
NIF system FeS cluster assembly NifU N-terminal
DNA replication/recombination mediator RecO N-terminal
Tryptophan synthase beta chain-like PALP
Cytochrome b561 bacterial/Ni-hydrogenase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
RND efflux pump membrane fusion protein barrel-sandwich
NADH:ubiquinone oxidoreductase 30kDa subunit
CobB/CobQ-like glutamine amidotransferase
Outer membrane protein beta-barrel domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Molybdopterin cofactor biosynthesis C (MoaC)
Type I restriction modification DNA specificity
Flagellar basal body rod protein N-terminal
Required for dimer formation and molybdate binding
N6 adenine-specific DNA methyltransferase N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Flagellar Assembly Protein A N-terminal region
Flagellar basal-body/hook protein C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Schiff-base intermediate with substrate; via pyruvic acid
Flagellar motor switch protein FliN-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cytochrome P460 domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Essential for prephenate dehydratase activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Translation elongation factor P/YeiP central
Periplasmic copper-binding protein NosD beta helix
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Important for autoinhibition of adenylyltransferase activity
Pyruvate/ketoisovalerate oxidoreductase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Magnesium transporter MgtE intracellular
RNA 2-O ribose methyltransferase substrate binding
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Major facilitator superfamily (MFS) profile
Damage-control phosphatase ARMT1-like metal-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Inner membrane protein YgaP-like transmembrane
O-(5'-phospho-DNA)-tyrosine intermediate
Alpha-D-phosphohexomutase alpha/beta/alpha
Involved in allosteric activation by GTP
Flagellar assembly protein FliH/Type III secretion system HrpE
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
STT3 subunit PglB C-terminal beta-barrel
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
TRAP C4-dicarboxylate transport system permease DctM subunit
Phosphatidylglycerol lysyltransferase C-terminal
UDP-N-acetylenolpyruvoylglucosamine reductase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Helix-hairpin-helix DNA-binding motif class 1
Major facilitator superfamily associated
Pyruvate phosphate dikinase AMP/ATP-binding
S-adenosylmethionine-dependent methyltransferase
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Pyridoxamine 5'-phosphate oxidase putative
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Important for beta-aspartyl-AMP intermediate formation
Sodium/calcium exchanger membrane region
Type II secretion system protein GspE N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Flagellar hook-length control protein-like C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alginate export domain-containing protein
Translation initiation factor IF-2 N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Butirosin biosynthesis protein H N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Small ribosomal subunit protein uS4 N-terminal
RNA binding; important for wobble base 34 recognition
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Gfo/Idh/MocA-like oxidoreductase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Periplasmic nitrate reductase, electron transfer subunit
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Large ribosomal subunit protein uL15/eL18
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
DNA-directed DNA polymerase family A palm
UDP N-acetylglucosamine O-acyltransferase C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA mismatch repair proteins mutS family
Plasminogen-binding protein PgbA N-terminal
Cytochrome c-552/4 domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Siroheme decarboxylase AsnC-like ligand binding
Curli production assembly/transport component CsgG
Pseudouridine synthase I TruA alpha/beta
Gamma-glutamylcyclotransferase AIG2-like
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Chromosomal replication initiator DnaA C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Resolvase/invertase-type recombinase catalytic
Moybdenum cofactor oxidoreductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Conserved virulence factor B-like winged helix
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Acyl-CoA dehydrogenase C-terminal bacterial-type
Formylmethanofuran dehydrogenase subunit E
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Prokaryotic-type class I peptide chain release factors
Tellurite resistance methyltransferase TehB-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Ysc84 actin-binding domain-containing protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Glycosyl transferase family 3 N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Alanyl-transfer RNA synthetases family profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Outer membrane lipoprotein-sorting protein
Cytochrome oxidase subunit II copper A binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Urease accessory protein UreH-like transmembrane
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Plays an important role in substrate specificity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
TIGR04219 family outer membrane beta-barrel protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Ribosomal RNA adenine methylase transferase N-terminal
Bacterial type II secretion system protein E
Phosphoribosylformylglycinamidine synthase linker
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Prepilin type IV endopeptidase peptidase
Glycosyltransferase subfamily 4-like N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein uL2 C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Organic solvent tolerance-like N-terminal
Nitrate/nitrite sensing protein domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Anthranilate synthase component I N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Interaction with polymerase core subunit RpoC
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Membrane fusion protein biotin-lipoyl like
Release factor glutamine methyltransferase N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Ribose-phosphate pyrophosphokinase N-terminal
Reversibly protonated during proton transport
N-end rule aminoacyl transferase C-terminal