Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Resolvase/invertase-type recombinase catalytic
Peptide methionine sulphoxide reductase MsrA
Tryptophan synthase beta chain-like PALP
TonB-dependent receptor-like beta-barrel
YVTN beta-propeller repeat-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Glycine cleavage T-protein C-terminal barrel
Transposase IS116/IS110/IS902 C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
NIF system FeS cluster assembly NifU N-terminal
ABC-type glycine betaine transport system substrate-binding
Anaphase-promoting complex subunit 4-like WD40
Pyruvate phosphate dikinase AMP/ATP-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Major facilitator superfamily (MFS) profile
Peptidase S9 prolyl oligopeptidase catalytic
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
N-end rule aminoacyl transferase C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Plays an important role in substrate specificity
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ABC transporter substrate-binding protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Helix-hairpin-helix DNA-binding motif class 1
O-(5'-phospho-DNA)-tyrosine intermediate
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Acetylserotonin O-methyltransferase dimerisation
TRAP C4-dicarboxylate transport system permease DctM subunit
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Cytochrome b561 bacterial/Ni-hydrogenase
Moybdenum cofactor oxidoreductase dimerisation
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Molybdopterin cofactor biosynthesis C (MoaC)
Important for beta-aspartyl-AMP intermediate formation
Magnesium-protoporphyrin IX methyltransferase C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Proline utilization A proline dehydrogenase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
CobB/CobQ-like glutamine amidotransferase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Interaction with polymerase core subunit RpoC
Solute-binding protein family 3/N-terminal
Cation-transporting P-type ATPase N-terminal
Periplasmic binding protein domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Polymerase/histidinol phosphatase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Membrane fusion protein biotin-lipoyl like
Phosphoribosylformylglycinamidine synthase linker
DNA mismatch repair proteins mutS family
Septum formation inhibitor MinC C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Thiamine pyrophosphate enzyme TPP-binding
RNA 2-O ribose methyltransferase substrate binding
Translation elongation factor P/YeiP central
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
PEP-CTERM protein-sorting domain-containing protein
Required for zinc-mediated homotetramerization and catalytic activity
O-(3'-phospho-DNA)-tyrosine intermediate
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
High potential iron-sulfur proteins family profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein uL15/eL18
PHA accumulation regulator DNA-binding N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Antitoxin Xre/MbcA/ParS-like toxin-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
HupH hydrogenase expression protein C-terminal
6-phosphogluconate dehydrogenase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Heat-inducible transcription repressor HrcA C-terminal
Bacterial type II secretion system protein E
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Alpha-glycerophosphate oxidase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Cytochrome C biogenesis protein transmembrane
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Flagellar motor switch protein FliN-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Putative Flp pilus-assembly TadG-like N-terminal
Periplasmic copper-binding protein NosD beta helix
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA replication/recombination mediator RecO N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Light-independent protochlorophyllide reductase subunit B-like C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Prokaryotic-type class I peptide chain release factors
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Sec translocon accessory complex subunit YajC
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Positions MEP for the nucleophilic attack
Probable periplasmic serine endoprotease DegP-like
Essential for prephenate dehydratase activity
Prepilin type IV endopeptidase peptidase
SsuA/THI5-like domain-containing protein
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
Photosynthetic reaction centre H subunit N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Outer membrane protein assembly factor BamA
Acyl-CoA dehydrogenase C-terminal bacterial-type
Ribosomal RNA adenine methylase transferase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Adaptive response protein AidB N-terminal
Thiol:disulfide interchange protein DsbD N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Penicillin-binding protein transpeptidase
Type VI secretion system IcmF C-terminal
Type II secretion system protein GspC N-terminal domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Gamma-butyrobetaine hydroxylase-like N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cysteine sulfenic acid (-SOH) intermediate
Glycosyl transferase family 3 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Cytochrome c-type biogenesis protein CcmF C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Gp5/Type VI secretion system Vgr protein OB-fold
Could be important to modulate the pK values of the two catalytic cysteine residues
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Exonuclease VII large subunit C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Ribulose bisphosphate carboxylase small subunit
Ribose-phosphate pyrophosphokinase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Haemolysin activator HlyB C-terminal domain-containing protein
Heme-copper oxidase subunit III family profile
Solute-binding protein family 3/N-terminal domain-containing protein
Type II secretion system protein GspE N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
Polysaccharide biosynthesis protein C-terminal
Alanyl-transfer RNA synthetases family profile
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Invasion associated locus B family protein
Autotransporter domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
SGNH hydrolase-type esterase domain-containing protein
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
RNA binding; important for wobble base 34 recognition
Ionotropic glutamate receptor C-terminal
Chromosomal replication initiator protein DnaA
Schiff-base intermediate with acetoacetate
Important for interaction with partner proteins
Schiff-base intermediate with dihydroxyacetone-P
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Polypeptide-transport-associated ShlB-type
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Pseudouridine synthase I TruA alpha/beta
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Guanylate kinase/L-type calcium channel beta subunit
Polysaccharide biosynthesis protein CapD-like
NADH:ubiquinone oxidoreductase 30kDa subunit
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Methionyl-tRNA synthetase anticodon-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
CagE TrbE VirB component of type IV transporter system central
BREX system Lon protease-like BrxL N-terminal
Reversibly protonated during proton transport
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Anthranilate synthase component I N-terminal
Release factor glutamine methyltransferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
CDP-alcohol phosphatidyltransferase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Endoribonuclease L-PSP/chorismate mutase-like
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Sodium/calcium exchanger membrane region
Outer membrane protein beta-barrel domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Mannose-6-phosphate isomerase type II C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL2 C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Transglycosylase SLT domain-containing protein
Electron transfer via tryptophanyl radical
UDP N-acetylglucosamine O-acyltransferase C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding