Glyoxalase/fosfomycin resistance/dioxygenase
Resolvase/invertase-type recombinase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
RNA polymerase sigma factor 70 region 4 type 2
Peptidase S9 prolyl oligopeptidase catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Tryptophan synthase beta chain-like PALP
Iron dependent repressor metal binding and dimerisation
Major facilitator superfamily (MFS) profile
TonB-dependent receptor-like beta-barrel
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Signal transduction histidine kinase internal region
Aconitase A/isopropylmalate dehydratase small subunit swivel
RND efflux pump membrane fusion protein barrel-sandwich
Glycosyltransferase subfamily 4-like N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Organic solvent tolerance-like N-terminal
Secretion system C-terminal sorting domain-containing protein
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
Sodium/calcium exchanger membrane region
Positions MEP for the nucleophilic attack
O-(5'-phospho-DNA)-tyrosine intermediate
Alpha-D-phosphohexomutase alpha/beta/alpha
Type I restriction modification DNA specificity
Lipocalin-like domain-containing protein
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Dihydrodipicolinate reductase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Glycoside hydrolase family 31 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Starch-binding associating with outer membrane
Choloylglycine hydrolase/NAAA C-terminal
Transposase IS116/IS110/IS902 C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glycosyl hydrolases family 2 sugar binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
TerB family tellurite resistance protein
Endoribonuclease L-PSP/chorismate mutase-like
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
SGNH hydrolase-type esterase domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Heme-copper oxidase subunit III family profile
Acyl-CoA dehydrogenase/oxidase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Polysaccharide biosynthesis protein CapD-like
3-keto-disaccharide hydrolase domain-containing protein
Membrane fusion protein biotin-lipoyl like
Cell wall-active antibiotics response LiaF-like C-terminal
Polysaccharide chain length determinant N-terminal
Transcriptional regulator AbiEi antitoxin N-terminal
Serine/threonine specific protein phosphatases
Fibrobacter succinogenes major paralogous
Fibrobacter succinogenes major paralogous domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Aminoacyl-transfer RNA synthetases class-II family profile
N6 adenine-specific DNA methyltransferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Peptidase M1 membrane alanine aminopeptidase
Phosphoinositide phospholipase C, Ca2+-dependent
YaiO family beta-barrel domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Protein containing PKD domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glycosyl-hydrolase 97 C-terminal oligomerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Pseudouridine synthase I TruA alpha/beta
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-110)
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Contractile injection system tube protein N-terminal
Translation elongation factor P/YeiP central
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Non-canonical purine NTP phosphatase/PRRC1
Alanyl-transfer RNA synthetases family profile
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
DNA mismatch repair proteins mutS family
Bacterial bifunctional deaminase-reductase C-terminal
6-phosphogluconate dehydrogenase C-terminal
tRNA pseudouridylate synthase B C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
SUF system FeS cluster assembly SufBD N-terminal
Surface glycan-binding protein B xyloglucan binding
Surface glycan-binding protein B xyloglucan binding domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Sodium symporter small subunit predicted
Beta-xylosidase C-terminal Concanavalin A-like
Penicillin-binding protein transpeptidase
Membrane insertase YidC/Oxa/ALB C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Proton acceptor; for glutaminase activity
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Polysaccharide biosynthesis protein C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Release factor glutamine methyltransferase N-terminal
Prokaryotic-type class I peptide chain release factors
Alginate export domain-containing protein
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Glycoside hydrolase family 57 N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Peptidase M43 pregnancy-associated plasma-A
Carbohydrate-binding domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Gliding motility-associated C-terminal domain-containing protein
Integral membrane protein YccS N-terminal
Shikimate dehydrogenase substrate binding N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Reversibly protonated during proton transport
peptide-methionine (R)-S-oxide reductase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gp5/Type VI secretion system Vgr protein OB-fold
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Electron transfer via tryptophanyl radical
ABC-type uncharacterised transport system
Ribose-phosphate pyrophosphokinase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Large ribosomal subunit protein uL2 C-terminal
Periplasmic component of the Tol biopolymer transport system
Schiff-base intermediate with acetaldehyde
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Thiosulphate:quinone oxidoreductase small subunit DoxA
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Small ribosomal subunit protein uS4 N-terminal
DNA-directed DNA polymerase family A palm
Gylcosyl hydrolase 115 C-terminal domain-containing protein
Anthranilate synthase component I N-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Involved in allosteric activation by GTP
Menaquinone biosynthesis protein MenD middle
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyl transferase family 3 N-terminal
Glycosyl hydrolase-like 10 domain-containing protein
Sialate O-acetylesterase domain-containing protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Haem-binding uptake Tiki superfamily ChaN
Glycine cleavage T-protein C-terminal barrel
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Insecticide toxin TcdB middle/N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Neutral/alkaline non-lysosomal ceramidase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Tetrahydrodipicolinate-N-succinyltransferase chain A
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Gly-cisPro motif, important for rejection of L-amino acids
Important for autoinhibition of adenylyltransferase activity
FAD-dependent oxidoreductase 2 FAD binding
Carbamoyl-phosphate synthase small subunit N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Phosphoribosylformylglycinamidine synthase
DNA replication/recombination mediator RecO N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Beta-hexosaminidase bacterial type N-terminal
Dihydrodipicolinate reductase C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Lysidine-tRNA(Ile) synthetase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphatidate phosphatase APP1 catalytic
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Molybdopterin cofactor biosynthesis C (MoaC)
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Trigger factor ribosome-binding bacterial
Moybdenum cofactor oxidoreductase dimerisation
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein uL15/eL18
Type IX secretion system protein PorV domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Thymidylate synthase/dCMP hydroxymethylase
Peptide methionine sulphoxide reductase MsrA
Plays an important role in substrate specificity
Cytochrome c-type biogenesis protein CcmF C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-118)
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Biopterin-dependent aromatic amino acid hydroxylase family profile
Exonuclease VII large subunit C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
AB hydrolase-1 domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Protein involved in meta-pathway of phenol degradation
TRAP C4-dicarboxylate transport system permease DctM subunit
Alpha-glycerophosphate oxidase C-terminal
Type 1 periplasmic binding fold superfamily protein
Carboxypeptidase regulatory-like domain-containing protein
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Saccharopine dehydrogenase-like C-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
ATP-grasp fold succinyl-CoA synthetase-type
Glycosyl hydrolase family 95 N-terminal domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Chromosomal replication initiator DnaA C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Urease accessory protein UreH-like transmembrane
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
RNA binding; important for wobble base 34 recognition
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Important for interaction with partner proteins