Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Outer membrane protein beta-barrel domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glycosyl transferase family 28 C-terminal
Threonine/serine exporter-like N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Helix-hairpin-helix DNA-binding motif class 1
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Tryptophan synthase beta chain-like PALP
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Intracellular proteinase inhibitor BsuPI
Intracellular proteinase inhibitor BsuPI domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Polysaccharide biosynthesis protein CapD-like
N-end rule aminoacyl transferase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Putative adhesin domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Prepilin type IV endopeptidase peptidase
Chalcone isomerase domain-containing protein
DNA polymerase III subunit delta C-terminal
TonB-dependent receptor-like beta-barrel domain-containing protein
TonB-dependent receptor-like beta-barrel
DNA-directed DNA polymerase family A palm
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Outer membrane protein assembly factor BamB
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Glycosyl transferase family 3 N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Gly-cisPro motif, important for rejection of L-amino acids
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Homogentisate 1,2-dioxygenase N-terminal
Heme-copper oxidase subunit III family profile
NIF system FeS cluster assembly NifU C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Organic solvent tolerance-like N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Histidine-specific methyltransferase SAM-dependent
Cupin 2 conserved barrel domain-containing protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
Peptidase S8 and S53 subtilisin kexin sedolisin
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
DNA mismatch repair proteins mutS family
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Penicillin-binding protein transpeptidase
DSBA-like thioredoxin domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Major facilitator superfamily (MFS) profile
Pyruvate dehydrogenase E1 component middle
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Exonuclease VII large subunit C-terminal
Chromosomal replication initiator DnaA C-terminal
Polymerase/histidinol phosphatase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Amidohydrolase 3 domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Reversibly protonated during proton transport
Sel1 domain protein repeat-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Type 4 fimbrial biogenesis protein PilX N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Lytic transglycosylase superhelical linker
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
RNA polymerase sigma factor 70 region 4 type 2
Important for substrate binding and specificity
Ribosomal RNA adenine methylase transferase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Polysaccharide chain length determinant N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Outer-membrane lipoprotein carrier protein
Glycine zipper 2TM domain-containing protein
Translation elongation factor P/YeiP central
Biopterin-dependent aromatic amino acid hydroxylase family profile
Thymidylate synthase/dCMP hydroxymethylase
Gamma-butyrobetaine hydroxylase-like N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Cytochrome b561 bacterial/Ni-hydrogenase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Anthranilate synthase component I N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Fibronectin type-III domain-containing protein
Outer membrane protein assembly factor BamE
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Signal transduction histidine kinase internal region
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Plays an important role in substrate specificity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA replication/recombination mediator RecO N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Quercetin 2,3-dioxygenase C-terminal cupin
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Positions MEP for the nucleophilic attack
Membrane fusion protein biotin-lipoyl like
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Acyl-CoA dehydrogenase C-terminal bacterial-type
Glucose-methanol-choline oxidoreductase C-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Type II restriction endonuclease EcoO109IR
Important for interaction with partner proteins
Carbamoyl-phosphate synthase small subunit N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Bacterial virulence factor lipase N-terminal
Bacterial virulence factor lipase N-terminal domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Glycine cleavage T-protein C-terminal barrel
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Bacterial type II secretion system protein E
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Plays an important role in discriminating NADH against NADPH
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Sugar fermentation stimulation protein C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycosyltransferase family 28 N-terminal
Pseudouridine synthase I TruA alpha/beta
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Peptide methionine sulphoxide reductase MsrA
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Acyltransferase MbtK/IucB-like conserved
Ribose-phosphate pyrophosphokinase N-terminal
Type II secretion system protein GspG C-terminal
Saccharopine dehydrogenase-like C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alanyl-transfer RNA synthetases family profile
Important for beta-aspartyl-AMP intermediate formation
Membrane insertase YidC/Oxa/ALB C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Sodium/calcium exchanger membrane region
RNA binding; important for wobble base 34 recognition
Nitrite/Sulfite reductase ferredoxin-like
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Arginine decarboxylase C-terminal helical
NIF system FeS cluster assembly NifU N-terminal
Electron transfer via tryptophanyl radical
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
RNA 2-O ribose methyltransferase substrate binding
Outer membrane protein assembly factor BamA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Lipopolysaccharide assembly protein A domain-containing protein
Virulence factor membrane-bound polymerase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Metallo-beta-lactamase domain-containing protein
Proton acceptor; for glutaminase activity
RNA methyltransferase SpoU/TrmH type C-terminal
Essential for prephenate dehydratase activity
Pyruvate phosphate dikinase AMP/ATP-binding
Peptidase M15C domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Interaction with polymerase core subunit RpoC