Pyruvate phosphate dikinase AMP/ATP-binding
Putative aromatic acid exporter C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Shikimate dehydrogenase substrate binding N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Tryptophan synthase beta chain-like PALP
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
SUF system FeS cluster assembly SufBD N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein uL6 alpha-beta
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Small ribosomal subunit protein uS4 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA mismatch repair proteins mutS family
Could be important to modulate the pK values of the two catalytic cysteine residues
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Major facilitator superfamily (MFS) profile
Glucosamine/galactosamine-6-phosphate isomerase
Carbamoyl-phosphate synthase small subunit N-terminal
RNA 2-O ribose methyltransferase substrate binding
Polysaccharide biosynthesis protein C-terminal
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Important for beta-aspartyl-AMP intermediate formation
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Polysaccharide chain length determinant N-terminal
Cation-transporting P-type ATPase N-terminal
Solute-binding protein family 3/N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Phosphotransferase system enzyme I N-terminal
Cell envelope-related transcriptional attenuator
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Plays an important role in substrate specificity
Transposase IS116/IS110/IS902 C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Phosphocysteine intermediate; for EIIB activity
Reversibly protonated during proton transport
Nitrite/Sulfite reductase ferredoxin-like
AraC-type arabinose-binding/dimerisation
ATP synthase F1 complex delta/epsilon subunit N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Penicillin-binding protein transpeptidase
Alanyl-transfer RNA synthetases family profile
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptide methionine sulphoxide reductase MsrA
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Metal ABC transporter substrate-binding protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
RNA binding; important for wobble base 34 recognition
Prokaryotic-type class I peptide chain release factors
Polysaccharide biosynthesis protein CapD-like
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Phosphatidic acid phosphatase type 2/haloperoxidase
Alpha-D-phosphohexomutase alpha/beta/alpha
NIF system FeS cluster assembly NifU N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Inosine/uridine-preferring nucleoside hydrolase
Transcriptional coactivator p15 (PC4) C-terminal
Schiff-base intermediate with acetaldehyde
Translation elongation factor P/YeiP central
O-(3'-phospho-DNA)-tyrosine intermediate
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Pseudouridine synthase I TruA alpha/beta
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA polymerase sigma factor 70 region 4 type 2
6-phosphogluconate dehydrogenase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
O-(phosphoribosyl dephospho-coenzyme A)serine
DNA polymerase III delta subunit C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycosyltransferase subfamily 4-like N-terminal
Polymerase/histidinol phosphatase N-terminal
Involved in allosteric activation by GTP
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
CobB/CobQ-like glutamine amidotransferase
Membrane insertase YidC/Oxa/ALB C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Resolvase/invertase-type recombinase catalytic
DNA replication/recombination mediator RecO N-terminal
Important for interaction with partner proteins
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Exonuclease VII large subunit C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Ribose-phosphate pyrophosphokinase N-terminal
Type VII secretion system protein EssD-like
YbaK/aminoacyl-tRNA synthetase-associated
Ionotropic glutamate receptor C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Signal recognition particle SRP54 helical bundle
Helix-turn-helix conjugative transposon-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptidase M1 membrane alanine aminopeptidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein uL15/eL18
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Mandelate racemase/muconate lactonizing enzyme C-terminal
Prepilin type IV endopeptidase peptidase
ABC-type glycine betaine transport system substrate-binding
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Choloylglycine hydrolase/NAAA C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Pyridoxamine 5'-phosphate oxidase putative
Alpha-glycerophosphate oxidase C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Release factor glutamine methyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding