Aconitase A/isopropylmalate dehydratase small subunit swivel
Outer membrane protein assembly factor BamE
Phosphocysteine intermediate; for EIIB activity
Helix-hairpin-helix DNA-binding motif class 1
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Required for dimer formation and molybdate binding
DNA mismatch repair proteins mutS family
Aminoacyl-transfer RNA synthetases class-II family profile
RND efflux pump membrane fusion protein barrel-sandwich
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Interacts with tRNA; defines subfamily-specific binding signature
TRAP C4-dicarboxylate transport system permease DctM subunit
Schiff-base intermediate with acetaldehyde
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Solute-binding protein family 3/N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Major facilitator superfamily associated
Exonuclease VII large subunit C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Major facilitator superfamily (MFS) profile
Outer membrane protein assembly factor BamA
Thiol:disulfide interchange protein DsbD
Integron-associated effector binding protein
Outer membrane protein assembly factor BamD
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cysteine sulfenic acid (-SOH) intermediate
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Chromosomal replication initiator protein DnaA
TonB-dependent receptor-like beta-barrel
RNA 2-O ribose methyltransferase substrate binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Disulphide bond isomerase DsbC/G N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA polymerase III delta subunit C-terminal
Anthranilate synthase component I N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Chromosomal replication initiator DnaA C-terminal
Transferrin-binding protein B C-lobe/N-lobe beta barrel
Alpha-D-phosphohexomutase alpha/beta/alpha
Cytochrome c-type biogenesis protein CcmF C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Reversibly protonated during proton transport
Ionotropic glutamate receptor C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Phosphotransferase system enzyme I N-terminal
Outer membrane protein assembly factor BamC
Periplasmic nitrate reductase, electron transfer subunit
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Organic solvent tolerance-like N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Lytic transglycosylase superhelical linker
Ribosomal RNA adenine methylase transferase N-terminal
Bacteriophage lambda Replication protein O N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Terminase large subunit-like endonuclease
Integral membrane protein YccS N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Release factor glutamine methyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Interaction with polymerase core subunit RpoC
O-(3'-phospho-DNA)-tyrosine intermediate
Could play a key role in the communication between the regulatory and the substrate sites
Ribose-phosphate pyrophosphokinase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Pseudouridine synthase I TruA alpha/beta
Tryptophan synthase beta chain-like PALP
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
ATP synthase F1 complex delta/epsilon subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
Alpha-glycerophosphate oxidase C-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Translocation and assembly module subunit TamA
Cytochrome C biogenesis protein transmembrane
Menaquinone biosynthesis protein MenD middle
YbaK/aminoacyl-tRNA synthetase-associated
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Autotransporter domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Lysidine-tRNA(Ile) synthetase C-terminal
Important for substrate binding and specificity
Glutathionylspermidine synthase pre-ATP-grasp-like
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
DNA polymerase III subunit delta C-terminal
Restriction system protein Mrr-like N-terminal
Formate-dependent nitrite reductase complex subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
Endolytic peptidoglycan transglycosylase RlpA
RNA binding; important for wobble base 34 recognition
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Prepilin type IV endopeptidase peptidase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Superoxide dismutase copper/zinc binding
CRISPR-associated protein Cas6 C-terminal
DNA replication/recombination mediator RecO N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Lipopolysaccharide export system protein LptA
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cytochrome b561 bacterial/Ni-hydrogenase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Membrane iron-sulfur containing protein FtrD-like
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Penicillin-binding protein transpeptidase
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein uL15/eL18
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Positions MEP for the nucleophilic attack
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Proline utilization A proline dehydrogenase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Essential for prephenate dehydratase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Mechanosensitive ion channel inner membrane
NIF system FeS cluster assembly NifU C-terminal
Survival protein SurE-like phosphatase/nucleotidase
UDP N-acetylglucosamine O-acyltransferase C-terminal
High-affinity zinc uptake system protein ZnuA
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein uL6 alpha-beta
Pyruvate dehydrogenase E1 component middle
Lipoprotein SmpA/OmlA domain-containing protein
Phosphomannose isomerase type I catalytic
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Tellurite resistance methyltransferase TehB-like
Involved in proton transfer during cleavage
Thymidylate synthase/dCMP hydroxymethylase
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
Involved in allosteric activation by GTP
Plays an important role in substrate specificity
D-galactose/methyl-galactoside binding periplasmic protein MglB
Chalcone isomerase domain-containing protein
Butirosin biosynthesis protein H N-terminal
Large ribosomal subunit protein uL2 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Membrane-bound lytic murein transglycosylase A
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Alanyl-transfer RNA synthetases family profile
Prokaryotic-type class I peptide chain release factors
Translation elongation factor P/YeiP central
Inner membrane protein YgaP-like transmembrane
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase