NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ribose-phosphate pyrophosphokinase N-terminal
Major facilitator superfamily (MFS) profile
L-seryl-tRNA selenium transferase N-terminal
Anthranilate synthase component I N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Polysaccharide biosynthesis protein CapD-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aminoacyl-transfer RNA synthetases class-II family profile
Bacterial bifunctional deaminase-reductase C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Small ribosomal subunit protein uS4 N-terminal
Erythromycin biosynthesis protein CIII-like central
RNA polymerase sigma factor 70 region 4 type 2
Chromosomal replication initiator DnaA C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Cell envelope-related transcriptional attenuator
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
PhoD-like phosphatase metallophosphatase
Na+/H+ antiporter MnhB subunit-related protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Activator of Hsp90 ATPase homologue 1-like C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
N6 adenine-specific DNA methyltransferase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Phosphoadenosine phosphosulphate reductase
Schiff-base intermediate with D-ribose 5-phosphate
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Polysaccharide chain length determinant N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Electron transfer flavoprotein alpha subunit C-terminal
Alanyl-transfer RNA synthetases family profile
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Styrene monooxygenase StyA putative substrate binding
Glycerophosphoryl diester phosphodiesterase family protein
Tryptophan synthase beta chain-like PALP
Pyridoxamine 5'-phosphate oxidase putative
FAD-dependent oxidoreductase 2 FAD binding
Ribulose bisphosphate carboxylase small subunit
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Solute-binding protein family 3/N-terminal
DnaJ homologue subfamily C member 28 conserved
Alpha-glycerophosphate oxidase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycine cleavage T-protein C-terminal barrel
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Thiamine pyrophosphate enzyme TPP-binding
2,4-diaminopentanoate dehydrogenase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
DNA-directed DNA polymerase family A palm
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyruvate phosphate dikinase AMP/ATP-binding
Transposase IS116/IS110/IS902 C-terminal
Prepilin type IV endopeptidase peptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycosyl transferase family 3 N-terminal
Bacterial type II secretion system protein E
Thiopeptide-type bacteriocin biosynthesis
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptidase M1 membrane alanine aminopeptidase
Putative regulatory protein FmdB Zinc ribbon
Involved in ionization of N3 of dUMP, leading to its activation
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
6-phosphogluconate dehydrogenase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Putative glycogen debranching enzyme N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Prokaryotic-type class I peptide chain release factors
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
RNA 2-O ribose methyltransferase substrate binding
SUF system FeS cluster assembly SufBD N-terminal
Important for beta-aspartyl-AMP intermediate formation
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Thiolase-like protein type 1 additional C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Large ribosomal subunit protein uL15/eL18
Reversibly protonated during proton transport
Helix-hairpin-helix DNA-binding motif class 1
Pyruvate dehydrogenase E1 component middle
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyrimidine nucleoside phosphorylase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Lactate utilization protein B C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Schiff-base intermediate with substrate; via topaquinone
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADH-rubredoxin oxidoreductase C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Transcription regulator AsnC/Lrp ligand binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphotransferase system enzyme I N-terminal
Polymerase/histidinol phosphatase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Tripartite tricarboxylate transporter family receptor
NIF system FeS cluster assembly NifU C-terminal
Type I restriction modification DNA specificity
O-(3'-phospho-DNA)-tyrosine intermediate
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Bacterial transcription activator effector binding
Penicillin-binding protein transpeptidase
Plays an important role in substrate specificity
Cytochrome oxidase subunit II copper A binding
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Exonuclease VII large subunit C-terminal
Anti-sigma-D factor RsdA sigma factor binding region
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL6 alpha-beta
Formamidopyrimidine-DNA glycosylase catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Removed in mature form; by autocatalysis
Homogentisate 1,2-dioxygenase C-terminal
Sporulation transcription regulator WhiA N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Myo-inositol-1-phosphate synthase GAPDH-like
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Adaptive response protein AidB N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Threonine/serine exporter-like N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Release factor glutamine methyltransferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Phosphocysteine intermediate; for EIIB activity
Carbamoyl-phosphate synthase small subunit N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome C biogenesis protein transmembrane
Cytochrome b/b6 N-terminal region profile
Molybdenum cofactor biosynthesis protein F N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Heme-copper oxidase subunit III family profile
Molybdopterin cofactor biosynthesis C (MoaC)
Methionyl-tRNA synthetase anticodon-binding
Translation elongation factor P/YeiP central
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Heat-inducible transcription repressor HrcA C-terminal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
DNA replication/recombination mediator RecO N-terminal
Essential for prephenate dehydratase activity
Interaction with polymerase core subunit RpoC
Ribosomal RNA adenine methylase transferase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Protein O-mannosyl-transferase C-terminal four TM
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Actinobacteria/chloroflexi VLRF1 release factor
Phenol hydroxylase C-terminal dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Cation-transporting P-type ATPase N-terminal
SGNH hydrolase-type esterase domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Sodium symporter small subunit predicted
Superoxide dismutase copper/zinc binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Lipocalin-like domain-containing protein
ABC-type glycine betaine transport system substrate-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Butirosin biosynthesis protein H N-terminal
Moybdenum cofactor oxidoreductase dimerisation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Proton acceptor; for glutaminase activity
Lipoprotein-anchoring transpeptidase ErfK/SrfK
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Gamma-glutamylcyclotransferase AIG2-like
DNA primase/polymerase bifunctional N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Peptide methionine sulphoxide reductase MsrA
TRAP C4-dicarboxylate transport system permease DctM subunit
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Ionotropic glutamate receptor C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Histidine-specific methyltransferase SAM-dependent
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL2 C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Glutathionylspermidine synthase pre-ATP-grasp-like
Nucleophile; cysteine thiosulfonate intermediate
Tricarboxylic transport membrane protein