Type I restriction enzyme R protein N-terminal
Putative beta-lactamase-inhibitor-like PepSY-like
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
TonB-dependent receptor-like beta-barrel
Important for autoinhibition of adenylyltransferase activity
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycosyl-hydrolase 97 C-terminal oligomerisation
tRNA pseudouridylate synthase B C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Nitroreductase domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
RNA polymerase sigma factor 70 region 4 type 2
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for interaction with partner proteins
Pseudouridine synthase I TruA alpha/beta
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
TonB-dependent receptor plug domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Release factor glutamine methyltransferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
NigD-like C-terminal beta sandwich domain-containing protein
Sulfatase-modifying factor enzyme domain-containing protein
Tryptophan synthase beta chain-like PALP
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Outer membrane protein beta-barrel domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Prokaryotic-type class I peptide chain release factors
Sulfatase N-terminal domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ribose-phosphate pyrophosphokinase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL2 C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Beta-hexosaminidase bacterial type N-terminal
Transglutaminase-like domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
RNA 2-O ribose methyltransferase substrate binding
SusE outer membrane protein domain-containing protein
General stress protein FMN-binding split barrel
Sodium/calcium exchanger membrane region
Phosphatidic acid phosphatase type 2/haloperoxidase
Major facilitator superfamily (MFS) profile
Large ribosomal subunit protein bL9 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Predicted pPIWI-associating nuclease group 2
Aminoacyl-transfer RNA synthetases class-II family profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
NADH:flavin oxidoreductase/NADH oxidase N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Polymerase/histidinol phosphatase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Proton acceptor; for glutaminase activity
Survival protein SurE-like phosphatase/nucleotidase
Membrane insertase YidC/Oxa/ALB C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
CRISPR-associated protein Cmr2 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Secretion system C-terminal sorting domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Polysaccharide biosynthesis protein C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glycine cleavage T-protein C-terminal barrel
Important for beta-aspartyl-AMP intermediate formation
Solute-binding protein family 3/N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Arginine decarboxylase C-terminal helical
Penicillin-binding protein transpeptidase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Endonuclease YhcR N-terminal domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Threonine/serine exporter-like N-terminal
Glycoside hydrolase family 57 N-terminal
Curli production assembly/transport component CsgG
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Gfo/Idh/MocA-like oxidoreductase N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Signal transduction histidine kinase internal region
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
DNA-directed DNA polymerase family A palm
Peptidase S9 prolyl oligopeptidase catalytic
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Reversibly protonated during proton transport
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Exonuclease VII large subunit C-terminal
Chromosomal replication initiator DnaA C-terminal
RNA binding; important for wobble base 34 recognition
Plays an important role in substrate specificity
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
SusD/RagB family nutrient-binding outer membrane lipoprotein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Phosphomannose isomerase type I catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
SUF system FeS cluster assembly SufBD N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Small ribosomal subunit protein uS4 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Tail specific protease domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA mismatch repair proteins mutS family
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phosphoadenosine phosphosulphate reductase
Lipocalin-like domain-containing protein
ParB-related ThiF-related cassette protein E
Phosphoethanolamine transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Fibronectin type-III domain-containing protein
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Saccharopine dehydrogenase-like C-terminal
Restriction endonuclease type II DpnII-like
Cytochrome b561 bacterial/Ni-hydrogenase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Large ribosomal subunit protein uL15/eL18
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Translation elongation factor P/YeiP central
Essential for prephenate dehydratase activity
T9SS C-terminal target domain-containing protein
Conserved virulence factor B-like winged helix
DNA replication/recombination mediator RecO N-terminal
Trigger factor ribosome-binding bacterial
6-phosphogluconate dehydrogenase C-terminal
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Positions MEP for the nucleophilic attack
Alpha galactosidase C-terminal beta sandwich
Shikimate dehydrogenase substrate binding N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Pyrroline-5-carboxylate reductase dimerisation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Peptidase M12B domain-containing protein
Sporulation stage II protein D amidase enhancer LytB N-terminal
Interchain (with Cys-220); in linked form
Interchain (with Cys-52); in linked form
Polysaccharide chain length determinant N-terminal
Alanyl-transfer RNA synthetases family profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cation-transporting P-type ATPase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fimbrillin-A associated anchor protein Mfa1 and Mfa2
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Helix-hairpin-helix DNA-binding motif class 1
Gliding motility protein SprA N-terminal
Glycosyl hydrolase family 30 beta sandwich
Carbamoyl-phosphate synthase small subunit N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding