Bacterial type II secretion system protein E
Organic solvent tolerance-like N-terminal
F420-non-reducing hydrogenase iron-sulfur subunit D
Dinitrogenase iron-molybdenum cofactor biosynthesis
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Water stress and hypersensitive response
Major facilitator superfamily (MFS) profile
Phosphatidylglycerol lysyltransferase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Acetyl-CoA hydrolase/transferase C-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
HicB-like antitoxin of toxin-antitoxin system
RNA 3'-terminal phosphate cyclase insert
Restriction endonuclease type I HsdR N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Carboxypeptidase regulatory-like domain-containing protein
tRNA pseudouridylate synthase B C-terminal
Polysaccharide biosynthesis protein CapD-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Phosphoribosylformylglycinamidine synthase linker
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Aminoacyl-transfer RNA synthetases class-II family profile
Putative Flp pilus-assembly TadG-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Manganese/iron superoxide dismutase C-terminal
Outer membrane protein beta-barrel domain-containing protein
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
CRISPR system ring nuclease SSO1393-like
Membrane fusion protein biotin-lipoyl like
Survival protein SurE-like phosphatase/nucleotidase
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Siroheme decarboxylase AsnC-like ligand binding
Pyruvate phosphate dikinase AMP/ATP-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
RsbT co-antagonist protein RsbRD N-terminal
Type II secretion system protein GspG C-terminal
Peptidase C39-like domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
ATP-dependent DNA helicase RecG C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Acetylserotonin O-methyltransferase dimerisation
Important for substrate specificity; cannot use PPi as phosphoryl donor
TonB-dependent receptor-like beta-barrel
Homocysteine biosynthesis enzyme sulfur-incorporation
DNA-directed DNA polymerase family B multifunctional
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Release factor glutamine methyltransferase N-terminal
Putative regulatory protein FmdB Zinc ribbon
Mandelate racemase/muconate lactonizing enzyme C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
UDP N-acetylglucosamine O-acyltransferase C-terminal
RNA 2-O ribose methyltransferase substrate binding
Tryptophan synthase beta chain-like PALP
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Translation elongation factor P/YeiP central
CobB/CobQ-like glutamine amidotransferase
Essential for prephenate dehydratase activity
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
L-seryl-tRNA selenium transferase N-terminal
Prepilin type IV endopeptidase peptidase
Membrane insertase YidC/Oxa/ALB C-terminal
Cation-transporting P-type ATPase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Methylene-tetrahydrofolate reductase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Nucleic acid binding OB-fold tRNA/helicase-type
Anthranilate synthase component I N-terminal
Cytochrome C biogenesis protein transmembrane
Nitrite/Sulfite reductase ferredoxin-like
Glycosyl transferase family 3 N-terminal
Plays an important role in substrate specificity
N6 adenine-specific DNA methyltransferase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Glycoside hydrolase family 57 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Formylmethanofuran dehydrogenase subunit E
Shikimate dehydrogenase substrate binding N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
PEP-CTERM sorting domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Polysaccharide chain length determinant N-terminal
Glycine-zipper-containing OmpA-like membrane
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA-directed DNA polymerase family A palm
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
CRISPR-associated protein Cas6 C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Resolvase/invertase-type recombinase catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Sodium/calcium exchanger membrane region
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Ribose-phosphate pyrophosphokinase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Damage-control phosphatase ARMT1-like metal-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glycoside hydrolase family 42 N-terminal domain-containing protein
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
RNA binding; important for wobble base 34 recognition
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phosphodiester glycosidase domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Alanyl-transfer RNA synthetases family profile
Microcin J25-processing protein McjB C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DnaJ homologue subfamily C member 28 conserved
Could be important to modulate the pK values of the two catalytic cysteine residues
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Proton acceptor; for glutaminase activity
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Large ribosomal subunit protein uL6 alpha-beta
DNA replication/recombination mediator RecO N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Phosphotransferase system enzyme I N-terminal
Chromosomal replication initiator DnaA C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Pyridoxamine 5'-phosphate oxidase putative
NIF system FeS cluster assembly NifU C-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Large ribosomal subunit protein uL2 C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NADH:ubiquinone oxidoreductase 30kDa subunit
ABC-type uncharacterised transport system
Lysidine-tRNA(Ile) synthetase C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
ABC-type transport auxiliary lipoprotein component
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
RNA polymerase sigma factor 70 region 4 type 2
Electron transfer flavoprotein alpha/beta-subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
ATP synthase F1 complex delta/epsilon subunit N-terminal
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein uL15/eL18