Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Small ribosomal subunit protein uS4 N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Positions MEP for the nucleophilic attack
Polymerase/histidinol phosphatase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aminoacyl-transfer RNA synthetases class-II family profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Thiamine pyrophosphate enzyme TPP-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Flagellar motor switch protein FliN-like C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL15/eL18
Release factor glutamine methyltransferase N-terminal
Glycine cleavage T-protein C-terminal barrel
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Membrane insertase YidC/Oxa/ALB C-terminal
Major facilitator superfamily (MFS) profile
Chromosomal replication initiator DnaA C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Important for beta-aspartyl-AMP intermediate formation
Sporulation stage IV protein A C-terminal
Schiff-base intermediate with acetaldehyde
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pyruvate phosphate dikinase AMP/ATP-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glycosyltransferase subfamily 4-like N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Transposase IS116/IS110/IS902 C-terminal
Iron hydrogenase large subunit C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
RNA 2-O ribose methyltransferase substrate binding
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Pyrimidine nucleoside phosphorylase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Sodium/calcium exchanger membrane region
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for autoinhibition of adenylyltransferase activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Plays an important role in substrate specificity
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Involved in ionization of N3 of dUMP, leading to its activation
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Trigger factor ribosome-binding bacterial
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Membrane fusion protein biotin-lipoyl like
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA mismatch repair proteins mutS family
Exonuclease VII large subunit C-terminal
Phosphoadenosine phosphosulphate reductase
Phosphatidylglycerol lysyltransferase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Important for interaction with partner proteins
Putative oxidoreductase/dehydrogenase Rossmann-like
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
NIF system FeS cluster assembly NifU C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Bacterial type II secretion system protein E
Type III secretion system flagellar brake protein YcgR PilZN
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Carbamoyl-phosphate synthase small subunit N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Tryptophan synthase beta chain-like PALP
Pseudouridine synthase I TruA alpha/beta
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Methylene-tetrahydrofolate reductase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Type II secretion system protein GspG C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
S-adenosyl-L-homocysteine hydrolase NAD binding
Prepilin type IV endopeptidase peptidase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Survival protein SurE-like phosphatase/nucleotidase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Sporulation transcription regulator WhiA N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Cytochrome b/b6 N-terminal region profile
Penicillin-binding protein transpeptidase
Glycosyl transferase family 3 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Dipicolinate synthase subunit A N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Phage terminase large subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Inner membrane protein YgaP-like transmembrane
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Helix-hairpin-helix DNA-binding motif class 1
Alpha-D-phosphohexomutase alpha/beta/alpha
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Important for substrate specificity; cannot use PPi as phosphoryl donor
RND efflux pump membrane fusion protein barrel-sandwich
Membrane iron-sulfur containing protein FtrD-like
NADH:ubiquinone oxidoreductase 30kDa subunit
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Thiamin pyrophosphokinase thiamin-binding
D-galactarate/Altronate dehydratase C-terminal
Cation-transporting P-type ATPase N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
RNA polymerase sigma factor 70 region 4 type 2
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Reversibly protonated during proton transport
Charge relay system; for autoendoproteolytic cleavage activity
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Translation elongation factor P/YeiP central
Formylmethanofuran dehydrogenase subunit E
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Pesticidal crystal protein Cry22Aa Ig-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cell envelope-related transcriptional attenuator
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Glycosyltransferase family 28 N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Siroheme decarboxylase AsnC-like ligand binding
Alanyl-transfer RNA synthetases family profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Threonine/serine exporter-like N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Essential for prephenate dehydratase activity
Heat-inducible transcription repressor HrcA C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Transcriptional regulator TetR C-terminal Firmicutes type
DNA replication/recombination mediator RecO N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
NIF system FeS cluster assembly NifU N-terminal
Involved in allosteric activation by GTP
Polysaccharide biosynthesis protein CapD-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Polysaccharide biosynthesis protein C-terminal
Polysaccharide chain length determinant N-terminal
Doubled CXXCH motif domain-containing protein
Aldehyde ferredoxin oxidoreductase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DNA-directed DNA polymerase family A palm
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Nitrite/Sulfite reductase ferredoxin-like
Sporulation stage II protein D amidase enhancer LytB N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Interaction with polymerase core subunit RpoC
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Flagellar hook-length control protein-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Damage-control phosphatase ARMT1-like metal-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Phosphoribosylformylglycinamidine synthase linker
Signal recognition particle SRP54 helical bundle
Could be important to modulate the pK values of the two catalytic cysteine residues
BAAT/Acyl-CoA thioester hydrolase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptidoglycan recognition protein family
Transcription regulator AsnC/Lrp ligand binding