Glycosyltransferase subfamily 4-like N-terminal
ABC transporter substrate-binding protein PnrA-like
Gamma-glutamylcyclotransferase AIG2-like
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Molybdopterin cofactor biosynthesis C (MoaC)
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Chromosomal replication initiator DnaA C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Mandelate racemase/muconate lactonizing enzyme C-terminal
Involved in allosteric activation by GTP
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Glycosyltransferase family 28 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Non-canonical purine NTP phosphatase/PRRC1
Membrane insertase YidC/Oxa/ALB C-terminal
Penicillin-binding protein transpeptidase
Major facilitator superfamily (MFS) profile
CRISPR-associated protein Cas6 C-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Polymerase/histidinol phosphatase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
NADH:ubiquinone oxidoreductase 30kDa subunit
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Septum formation inhibitor MinC C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glycoside hydrolase family 31 N-terminal
RNA binding; important for wobble base 34 recognition
Moybdenum cofactor oxidoreductase dimerisation
Large ribosomal subunit protein uL2 C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Trigger factor ribosome-binding bacterial
Cytochrome C biogenesis protein transmembrane
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
SUF system FeS cluster assembly SufBD N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
LPXTG-motif cell wall anchor domain protein
6-phosphogluconate dehydrogenase C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Prepilin type IV endopeptidase peptidase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Heat-inducible transcription repressor HrcA C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Polysaccharide biosynthesis protein C-terminal
Release factor glutamine methyltransferase N-terminal
Alanyl-transfer RNA synthetases family profile
Glycine cleavage T-protein C-terminal barrel
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Small ribosomal subunit protein uS4 N-terminal
Superoxide dismutase copper/zinc binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
TRAP C4-dicarboxylate transport system permease DctM subunit
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Bacterial type II secretion system protein E
Glycosyl transferase family 3 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
S-adenosylmethionine-dependent methyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
V-type ATP synthase subunit I N-terminal
Vacuolar ATPase subunit I N-terminal proximal lobe
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA-directed DNA polymerase family A palm
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL6 alpha-beta
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Probable endolytic peptidoglycan transglycosylase RlpA
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Positions MEP for the nucleophilic attack
3-keto-disaccharide hydrolase domain-containing protein
Probable transposase IS891/IS1136/IS1341
Cell envelope-related transcriptional attenuator
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alpha-glycerophosphate oxidase C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Ribosomal RNA adenine methylase transferase N-terminal
Sodium/calcium exchanger membrane region
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
O-(5'-phospho-DNA)-tyrosine intermediate
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Heme-copper oxidase subunit III family profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Calcium/calmodulin-dependent protein kinase II association-domain
YbaK/aminoacyl-tRNA synthetase-associated
Adaptive response protein AidB N-terminal
ATP-dependent DNA helicase RecG C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
ATPsynthase alpha/beta subunit N-terminal extension
RNA polymerase sigma factor 70 region 4 type 2
Resolvase/invertase-type recombinase catalytic
Translation elongation factor P/YeiP central
Ribose-phosphate pyrophosphokinase N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Large ribosomal subunit protein uL15/eL18
Outer membrane protein beta-barrel domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ABC-type glycine betaine transport system substrate-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Tricarboxylic transport membrane protein
Phosphomannose isomerase type I catalytic
Pseudouridine synthase I TruA alpha/beta
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Outer membrane lipoprotein-sorting protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
UDP N-acetylglucosamine O-acyltransferase C-terminal
Peptide methionine sulphoxide reductase MsrA
Glucosamine/galactosamine-6-phosphate isomerase
S-adenosyl-L-homocysteine hydrolase NAD binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Involved in ionization of N3 of dUMP, leading to its activation
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Carbamoyl-phosphate synthase small subunit N-terminal
Tryptophan synthase beta chain-like PALP
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
DNA replication/recombination mediator RecO N-terminal
Plays an important role in substrate specificity
Thiamin pyrophosphokinase thiamin-binding
Peptidase S9 prolyl oligopeptidase catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
RNA methyltransferase SpoU/TrmH type C-terminal
Important for interaction with partner proteins
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA-directed RNA polymerase RpoA/D/Rpb3-type
NIF system FeS cluster assembly NifU N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Phosphodiester glycosidase domain-containing protein
Survival protein SurE-like phosphatase/nucleotidase
PrcB C-terminal domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
Arginine decarboxylase C-terminal helical
Glycosyl transferase family 28 C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Inner membrane protein YgaP-like transmembrane