Activator of Hsp90 ATPase homologue 1-like C-terminal
RlpA-like protein double-psi beta-barrel
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
RNA 2-O ribose methyltransferase substrate binding
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Aminoacyl-transfer RNA synthetases class-II family profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribosomal RNA adenine methylase transferase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Sulfatase-modifying factor enzyme domain-containing protein
Major facilitator superfamily (MFS) profile
Small ribosomal subunit protein uS4 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
TonB-dependent receptor-like beta-barrel
Sodium symporter small subunit predicted
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Haem-binding uptake Tiki superfamily ChaN
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
N6 adenine-specific DNA methyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Outer membrane protein beta-barrel domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Type VII secretion system protein EssD-like
Tryptophan synthase beta chain-like PALP
Electron transfer via tryptophanyl radical
Curli production assembly/transport component CsgE
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RND efflux pump membrane fusion protein barrel-sandwich
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Type IX secretion system protein PorV domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Signal transduction histidine kinase internal region
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Pseudouridine synthase I TruA alpha/beta
Cytochrome c-type biogenesis protein CcmF C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Beta-xylosidase C-terminal Concanavalin A-like
Large ribosomal subunit protein uL15/eL18
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Peptidase C14 caspase domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycoside hydrolase family 57 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Arabinogalactan endo-beta-1,4-galactanase
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
ABC-type uncharacterised transport system
Lipocalin-like domain-containing protein
Alanyl-transfer RNA synthetases family profile
Alpha-L-rhamnosidase six-hairpin glycosidase
Pyridoxamine 5'-phosphate oxidase putative
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Secretion system C-terminal sorting domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glycoside hydrolase GH146 substrate-binding
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Important for autoinhibition of adenylyltransferase activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Heme-copper oxidase subunit III family profile
Membrane fusion protein biotin-lipoyl like
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Chromosomal replication initiator DnaA C-terminal
Polymerase/histidinol phosphatase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
DNA mismatch repair proteins mutS family
Important for substrate specificity; cannot use PPi as phosphoryl donor
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tellurite resistance methyltransferase TehB-like
Gly-cisPro motif, important for rejection of L-amino acids
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cation-transporting P-type ATPase N-terminal
Glycine cleavage T-protein C-terminal barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
SusD-like N-terminal domain-containing protein
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
tRNA pseudouridylate synthase B C-terminal
Anthranilate synthase component I N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Penicillin-binding protein transpeptidase
Polysaccharide biosynthesis protein CapD-like
Type I restriction modification DNA specificity
Transition state stabilizer; via amide nitrogen
Na+/H+ antiporter MnhB subunit-related protein
DNA replication/recombination mediator RecO N-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Sialate O-acetylesterase domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Translation elongation factor P/YeiP central
Peptidase M1 membrane alanine aminopeptidase
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Exonuclease VII large subunit C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Thymidylate synthase/dCMP hydroxymethylase
Important for interaction with partner proteins
Lysidine-tRNA(Ile) synthetase C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Periplasmic component of the Tol biopolymer transport system
N-sulphoglucosamine sulphohydrolase C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Helix-hairpin-helix DNA-binding motif class 1
Could be important to modulate the pK values of the two catalytic cysteine residues
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Plays an important role in substrate specificity
Large ribosomal subunit protein uL2 C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
S-adenosylmethionine-dependent methyltransferase
Polysaccharide chain length determinant N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Urease accessory protein UreH-like transmembrane
Polysaccharide biosynthesis protein C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Beta-hexosaminidase bacterial type N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Protein SirB1 N-terminal domain-containing protein
Type II restriction enzyme and methyltransferase RM.Eco57I-like
TRAP C4-dicarboxylate transport system permease DctM subunit
YaiO family beta-barrel domain-containing protein
Leucine Rich Repeat (LRR)-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Sodium/calcium exchanger membrane region
Homogentisate 1,2-dioxygenase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Phosphatidic acid phosphatase type 2/haloperoxidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Saccharopine dehydrogenase-like C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Schiff-base intermediate with acetaldehyde
ATP-dependent DNA helicase RecG C-terminal
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Gliding motility-associated C-terminal domain-containing protein
Non-canonical purine NTP phosphatase/PRRC1
O-(3'-phospho-DNA)-tyrosine intermediate
NAD(P) transhydrogenase alpha subunit C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cell wall-active antibiotics response LiaF-like C-terminal
Proton acceptor; for glutaminase activity
Cytochrome C biogenesis protein transmembrane
Nitrite/Sulfite reductase ferredoxin-like
Glycosyl-hydrolase 97 C-terminal oligomerisation
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Reversibly protonated during proton transport
Carboxypeptidase-like regulatory domain-containing protein
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-109)
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Alpha-glycerophosphate oxidase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-117)
Trigger factor ribosome-binding bacterial
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
O-(5'-phospho-DNA)-tyrosine intermediate
SusE outer membrane protein domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycoside hydrolase family 31 N-terminal
DNA-directed DNA polymerase family A palm
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Menaquinone biosynthesis protein MenD middle
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Prokaryotic-type class I peptide chain release factors
Glycosyl transferase family 3 N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
RNA binding; important for wobble base 34 recognition
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal