Solute-binding protein family 3/N-terminal
DNA-directed DNA polymerase family A palm
Alpha-glycerophosphate oxidase C-terminal
TonB-dependent receptor-like beta-barrel
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Peptidase M20 dimerisation domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyltransferase subfamily 4-like N-terminal
Flagellar motor switch protein FliN-like C-terminal
Pyrroline-5-carboxylate reductase dimerisation
Resolvase/invertase-type recombinase catalytic
PQQ-dependent catabolism-associated beta-propeller protein
General stress protein FMN-binding split barrel
Activator of Hsp90 ATPase homologue 1-like C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
N-end rule aminoacyl transferase C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
NIF system FeS cluster assembly NifU N-terminal
Organic solvent tolerance-like N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Alpha-D-phosphohexomutase alpha/beta/alpha
Hexachlorocyclohexane dehydrochlorinase 2
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
CobB/CobQ-like glutamine amidotransferase
Type IV secretion system coupling protein TraD DNA-binding
Heme-copper oxidase subunit III family profile
Glycine cleavage T-protein C-terminal barrel
SMODS-associating 2TM beta-strand rich effector
Bacterial surface antigen (D15) domain-containing protein
Exonuclease VII large subunit C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Outer membrane protein beta-barrel domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Chromosomal replication initiator DnaA C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
O-(5'-phospho-DNA)-tyrosine intermediate
Nitrite/Sulfite reductase ferredoxin-like
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Alanyl-transfer RNA synthetases family profile
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Autotransporter domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Major facilitator superfamily (MFS) profile
Heat-inducible transcription repressor HrcA C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Could play a key role in the communication between the regulatory and the substrate sites
Important for interaction with partner proteins
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Ribose-phosphate pyrophosphokinase N-terminal
Histidine-specific methyltransferase SAM-dependent
Polysaccharide chain length determinant N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
ATP synthase F1 complex delta/epsilon subunit N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
2,5-dichlorohydroquinone reductive dechlorinase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
DNA mismatch repair proteins mutS family
Putative Flp pilus-assembly TadG-like N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Deacetylase PdaC domain-containing protein
Electron transfer via tryptophanyl radical
Antitoxin Xre/MbcA/ParS-like toxin-binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Glycosyl transferase family 3 N-terminal
Mannose-6-phosphate isomerase type II C-terminal
SMODS-associated and fused to various effectors
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Peptide methionine sulphoxide reductase MsrA
O-(3'-phospho-DNA)-tyrosine intermediate
Translation elongation factor P/YeiP central
Proton acceptor; for glutaminase activity
Lipoprotein SmpA/OmlA domain-containing protein
Outer membrane protein assembly factor BamD
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Methionyl-tRNA synthetase anticodon-binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Plays an important role in substrate specificity
Prepilin type IV endopeptidase peptidase
S-adenosylmethionine-dependent methyltransferase
Large ribosomal subunit protein uL2 C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
RNA 2-O ribose methyltransferase substrate binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Cobaltochelatase subunit CobS N-terminal
Outer membrane protein assembly factor BamA
CagE TrbE VirB component of type IV transporter system central
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Signal transduction histidine kinase dimerisation/phosphoacceptor
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
S-adenosyl-L-homocysteine hydrolase NAD binding
Disulphide bond isomerase DsbC/G N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Phosphoadenosine phosphosulphate reductase
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH-rubredoxin oxidoreductase C-terminal
tRNA pseudouridylate synthase B C-terminal
Superoxide dismutase copper/zinc binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Poly-beta-hydroxybutyrate polymerase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Ribosomal RNA adenine methylase transferase N-terminal
Interaction with polymerase core subunit RpoC
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pseudouridine synthase I TruA alpha/beta
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Heavy-metal-associated domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Penicillin-binding protein transpeptidase
Type II secretion system protein GspG C-terminal
PHA accumulation regulator DNA-binding N-terminal
Predicted DNA-binding protein ribbon-helix-helix
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Polypeptide-transport-associated ShlB-type
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Alginate export domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Mandelate racemase/muconate lactonizing enzyme C-terminal
Quinohemoprotein amine dehydrogenase alpha subunit haem binding domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Important for beta-aspartyl-AMP intermediate formation
Tryptophan synthase beta chain-like PALP
TtsA-like Glycoside hydrolase family 108
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Signal recognition particle SRP54 helical bundle
SUF system FeS cluster assembly SufBD N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Nucleophile; cysteine thiosulfonate intermediate
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Prokaryotic-type class I peptide chain release factors
Myo-inositol-1-phosphate synthase GAPDH-like
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Phosphatidic acid phosphatase type 2/haloperoxidase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Proline utilization A proline dehydrogenase N-terminal
BREX system Lon protease-like BrxL N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Helix-hairpin-helix DNA-binding motif class 1
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Probable periplasmic serine endoprotease DegP-like
NAD(P) transhydrogenase alpha subunit C-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Cysteine sulfenic acid (-SOH) intermediate
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
DNA replication/recombination mediator RecO N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Histidine phosphotransferase ChpT C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphoribosylformylglycinamidine synthase linker
Pyrimidine nucleoside phosphorylase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-100)
C-type lysozyme inhibitor domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Release factor glutamine methyltransferase N-terminal
Saccharopine dehydrogenase-like C-terminal
Bacterial type II secretion system protein E
Terminase large subunit gp17-like C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Hexachlorocyclohexane dehydrochlorinase 1
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Tetrahydrodipicolinate-N-succinyltransferase chain A
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Peptide methionine sulfoxide reductase MsrA
CDP-alcohol phosphatidyltransferase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
YMGG-like Gly-zipper domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Cytochrome c-type biogenesis protein CcmF C-terminal
Putative glycogen debranching enzyme N-terminal
Reversibly protonated during proton transport
Cytochrome c-type biogenesis protein CcmE
Right handed beta helix domain-containing protein
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Essential for prephenate dehydratase activity
YbgF trimerisation domain-containing protein
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Polysaccharide biosynthesis protein CapD-like
Signal transduction histidine kinase HWE region
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Large ribosomal subunit protein uL15/eL18
Flagellar assembly protein T N-terminal domain-containing protein
RNA binding; important for wobble base 34 recognition
Moybdenum cofactor oxidoreductase dimerisation
Survival protein SurE-like phosphatase/nucleotidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Small ribosomal subunit protein uS4 N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glycine-rich cell wall structural protein
Increases nucleophilicity of active site Cys
Endoribonuclease L-PSP/chorismate mutase-like
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Glucan biosynthesis periplasmic MdoG C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal domain-containing protein