2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Bacterial transcription activator effector binding
Tryptophan synthase beta chain-like PALP
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Thiamine pyrophosphate enzyme TPP-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Sporulation transcription regulator WhiA N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Phosphocysteine intermediate; for EIIB activity
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA polymerase sigma factor 70 region 4 type 2
N-sulphoglucosamine sulphohydrolase C-terminal
CobB/CobQ-like glutamine amidotransferase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
DNA mismatch repair proteins mutS family
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Putative aromatic acid exporter C-terminal
RlpA-like protein double-psi beta-barrel
Could play a key role in the communication between the regulatory and the substrate sites
O-(5'-phospho-DNA)-tyrosine intermediate
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Major facilitator superfamily (MFS) profile
Dinitrogenase iron-molybdenum cofactor biosynthesis
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Gly-cisPro motif, important for rejection of L-amino acids
Toxin-antitoxin system YwqK family antitoxin
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
TonB-dependent receptor-like beta-barrel
Mandelate racemase/muconate lactonizing enzyme C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Nitrite/Sulfite reductase ferredoxin-like
Interaction with polymerase core subunit RpoC
Pseudouridine synthase I TruA alpha/beta
F420-non-reducing hydrogenase iron-sulfur subunit D
RND efflux pump membrane fusion protein barrel-sandwich
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Sugar fermentation stimulation protein C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cell division protein FtsQ/DivIB C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
RNA 2-O ribose methyltransferase substrate binding
Increases nucleophilicity of active site Cys
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Threonine/serine exporter-like N-terminal
Plays an important role in substrate specificity
Murein L,D-transpeptidase catalytic domain family protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Alanyl-transfer RNA synthetases family profile
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
D-galactarate/Altronate dehydratase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Polysaccharide biosynthesis protein CapD-like
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Schiff-base intermediate with acetaldehyde
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Heat-inducible transcription repressor HrcA C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
ABC-type glycine betaine transport system substrate-binding
Sporulation stage II protein D amidase enhancer LytB N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Ribosomal RNA adenine methylase transferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL2 C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Transposase IS116/IS110/IS902 C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Lysidine-tRNA(Ile) synthetase C-terminal
Bacterial type II secretion system protein E
Terminase large subunit-like endonuclease
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA polymerase III beta sliding clamp C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA replication/recombination mediator RecO N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Cation-transporting P-type ATPase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribose-phosphate pyrophosphokinase N-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphomannose isomerase type I catalytic
Shikimate dehydrogenase substrate binding N-terminal
Important for guanine/8-oxoguanine distinction
Aspartate/homoserine dehydrogenase NAD-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Polysaccharide biosynthesis protein C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Molybdopterin cofactor biosynthesis C (MoaC)
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Lipocalin-like domain-containing protein
Prepilin type IV endopeptidase peptidase
Ribonucleotide reductase large subunit C-terminal
Involved in proton transfer during cleavage
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Transglycosylase SLT domain-containing protein
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
NIF system FeS cluster assembly NifU N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Phosphoadenosine phosphosulphate reductase
Phosphatidylglycerol lysyltransferase C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
CRISPR system ring nuclease SSO1393-like
5-glutamyl coenzyme A thioester intermediate
Organic solvent tolerance-like N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyruvate phosphate dikinase AMP/ATP-binding
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Tyrosine specific protein phosphatases domain-containing protein
Essential for prephenate dehydratase activity
Gfo/Idh/MocA-like oxidoreductase C-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Positions MEP for the nucleophilic attack
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
ATP synthase F1 complex delta/epsilon subunit N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Phosphoribosylformylglycinamidine synthase linker
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Small ribosomal subunit protein uS4 N-terminal
DNA-directed DNA polymerase family A palm
Autotransporter domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Polypeptide-transport-associated ShlB-type
Translation elongation factor P/YeiP central
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Aromatic hydrocarbon degradation protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Choloylglycine hydrolase/NAAA C-terminal
Reversibly protonated during proton transport
Large ribosomal subunit protein uL6 alpha-beta
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Exonuclease VII large subunit C-terminal
Release factor glutamine methyltransferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
NIF system FeS cluster assembly NifU C-terminal
Involved in tetramerization or stability of the tetramer
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Asp23/Gls24 family envelope stress response protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL15/eL18
BREX system Lon protease-like BrxL N-terminal
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Putative host cell surface-exposed lipoprotein Ltp-like HTH region domain-containing protein
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Thiamin pyrophosphokinase thiamin-binding
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity