Neurotransmitter-gated ion-channel ligand-binding
Neurotransmitter-gated ion-channel transmembrane
G-protein coupled receptors family 1 profile
Phosphatidylserine amidated glycine; alternate
Cation-transporting P-type ATPase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Spindle assembly abnormal protein 6 N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Major facilitator superfamily (MFS) profile
Interaction with phosphoserine on interacting protein
ABC-type uncharacterised transport system
Protein-arginine deiminase (PAD) N-terminal
Protein-arginine deiminase (PAD) central
Voltage-gated hydrogen channel 1 C-terminal membrane-localisation
Anaphase-promoting complex subunit 4-like WD40
Histone-binding protein RBBP4 N-terminal
Potassium channel tetramerisation-type BTB
dolichyl-phosphate-mannose--protein mannosyltransferase
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein
A disintegrin and metalloproteinase with thrombospondin motifs 16
Schiff-base intermediate with acetaldehyde
Choloylglycine hydrolase/NAAA C-terminal
Serine/threonine specific protein phosphatases
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Platelet-derived growth factor receptor-like protein
Post-GPI attachment to proteins factor 3
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Histone deacetylase complex subunit SAP130 C-terminal
Vacuolar protein sorting-associated protein 54 N-terminal
N-end rule aminoacyl transferase C-terminal
Nucleolus and neural progenitor protein-like N-terminal
Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central
Acetylserotonin O-methyltransferase dimerisation
Protein phosphatase 1 regulatory subunit 26 N-terminal
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate
SUMO-activating enzyme subunit 2 C-terminal
Ubiquitin/SUMO-activating enzyme ubiquitin-like
TATA-binding protein interacting (TIP20)
Bactericidal permeability-increasing protein
Lipid-binding serum glycoprotein C-terminal
Lipid-binding serum glycoprotein N-terminal
Histone-arginine methyltransferase CARM1 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ionotropic glutamate receptor C-terminal
Ionotropic glutamate receptor L-glutamate and glycine-binding
Glycosyl transferase family 28 C-terminal
Pre-mRNA processing factor 4 (PRP4)-like
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Adenomatous polyposis coli N-terminal dimerisation
Adenomatous polyposis coli protein basic
Activator of Hsp90 ATPase AHSA1-like N-terminal
GDP-fucose protein O-fucosyltransferase 1
Essential for stabilizing binding to COTL1
Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA-directed RNA polymerase RBP11-like dimerisation
G-protein coupled receptors family 2 profile 2
G-protein coupled receptors family 2 profile 2 domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Aminoacyl-transfer RNA synthetases class-II family profile
Translation initiation factor beta propellor-like
GPI-GlcNAc transferase complex PIG-H component conserved
Pyrroline-5-carboxylate reductase catalytic N-terminal
Inward rectifier potassium channel C-terminal
Potassium channel inwardly rectifying transmembrane
Phosphatidic acid phosphatase type 2/haloperoxidase
S-adenosyl-L-homocysteine hydrolase NAD binding
RNA 3'-terminal phosphate cyclase insert
G-protein coupled receptors family 2 profile 1
Gamma-aminobutyric acid receptor subunit alpha-5
E3 ubiquitin-protein ligase Arkadia N-terminal
G-protein coupled receptors family 3 profile
Damage-control phosphatase ARMT1-like metal-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed RNA polymerase III subunit RPC5 C-terminal
Collagen IV NC1 domain-containing protein
Phosphomannose isomerase type I C-terminal
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Integrator complex subunit 14 C-terminal
Integrator complex subunit 14 beta-barrel
DNA mismatch repair proteins mutS family
Voltage-dependent calcium channel alpha-1 subunit IQ
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyruvate dehydrogenase E1 component subunit alpha
Large ribosomal subunit protein uL4 C-terminal
Immunoglobulin subtype domain-containing protein
Potassium channel inwardly rectifying Kir N-terminal
Transcription factor CBF/NF-Y/archaeal histone
NACHT, LRR and PYD domains-containing protein 12-like
Nucleoporin Nup133/Nup155-like C-terminal
Nucleoporin Nup133/Nup155-like N-terminal
TRF2-interacting telomeric protein/Rap1 C-terminal
Proto-oncogene tyrosine-protein kinase receptor Ret
Trafficking protein particle complex subunit 11
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Peptidase S9 prolyl oligopeptidase catalytic
Interaction with galactose moiety of substrate glycoprotein
Multiple epidermal growth factor-like domains protein 8
Centromere kinetochore component CENP-T N-terminal
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
T-cell surface glycoprotein CD3 zeta chain
Endoplasmic reticulum vesicle transporter C-terminal
Endoplasmic reticulum vesicle transporter N-terminal
Chromatin assembly factor 1 subunit B C-terminal
U3 small nucleolar RNA-associated protein 13 C-terminal
LKB1 serine/threonine kinase interacting protein 1 N-terminal
Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Janus kinase and microtubule-interacting protein C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Failed axon connections homolog N-terminal
Ubiquitin-activating enzyme E1 C-terminal
Arginine vasopressin-induced protein 1/transcriptional and immune response regulator
Pseudouridine synthase I TruA alpha/beta
RNA polymerase III subunit RPC82-related helix-turn-helix
BMP and activin membrane-bound inhibitor C-terminal
BMP and activin membrane-bound inhibitor N-terminal
BMP and activin membrane-bound inhibitor homolog
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
G-protein coupled receptors family 3 profile domain-containing protein
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Harmonin-binding protein USHBP1 PDZ-binding
Clathrin/coatomer adaptor adaptin-like N-terminal
Coatomer beta subunit appendage platform
Nuclear condensin complex subunit 3 C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Multiple myeloma tumor-associated protein 2-like N-terminal
CBF1-interacting co-repressor CIR N-terminal
Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium
Spermatogenesis-associated protein 1 C-terminal
Heme-copper oxidase subunit III family profile
Thymidylate synthase/dCMP hydroxymethylase
receptor protein serine/threonine kinase
Small ribosomal subunit protein mS23 conserved
tRNA-splicing endonuclease subunit Sen54 N-terminal
Activity-regulated cytoskeleton-associated protein C-terminal
Activity-regulated cytoskeleton-associated protein N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
tRNA pseudouridylate synthase B C-terminal
Transmembrane protein TMEM132 C-terminal
Transmembrane protein TMEM132 N-terminal
Multiple epidermal growth factor-like domains protein 6
U3 small nucleolar RNA-associated protein 15 C-terminal
Sodium/calcium exchanger membrane region
Sodium/calcium exchanger membrane region domain-containing protein
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Dynein regulatory complex protein 1 C-terminal
Dynein regulatory complex protein 1/2 N-terminal
Gamma-aminobutyric acid receptor subunit gamma-2
Dynein heavy chain ATP-binding dynein motor region
Superoxide dismutase copper/zinc binding
Fibronectin type-III domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
Large ribosomal subunit protein uL15/eL18
Zinc finger protein 750-like zinc finger
Tumour necrosis factor receptor 13C TALL-1 binding
A kinase-anchoring proteins AKAP-5 and AKAP-12 calmodulin (CaM)-binding
Opioid growth factor receptor (OGFr) conserved
Cleavage/polyadenylation specificity factor A subunit C-terminal
Cleavage/polyadenylation specificity factor A subunit N-terminal
Rad21/Rec8-like protein C-terminal eukaryotic
ATP-grasp fold succinyl-CoA synthetase-type
Formamidopyrimidine-DNA glycosylase catalytic
Ribosomal RNA-processing protein 12-like conserved
Peptidase M14 carboxypeptidase A domain-containing protein
Tetratricopeptide repeat protein 5 OB fold
Parathyroid hormone/parathyroid hormone-related peptide receptor
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
V-type proton ATPase subunit S1/VOA1 transmembrane
vitamin-K-epoxide reductase (warfarin-sensitive)
Potassium channel voltage dependent KCNQ C-terminal
Ran-GTPase activating protein 1 C-terminal
Telomere-associated protein Rif1 N-terminal
Telomerase activating protein Est1-like N-terminal
Endoplasmic reticulum resident protein 29
Endoplasmic reticulum resident protein 29 C-terminal
U2A'/phosphoprotein 32 family A C-terminal
Mitochondrial apoptosis-inducing factor C-terminal
Translation elongation factor IF5A C-terminal
Homologous-pairing protein 2 winged helix
Gamma-aminobutyric acid receptor subunit gamma-1
Lethal giant larvae (Lgl)-like C-terminal
DNA polymerase alpha catalytic subunit N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Zinc finger DNA-directed DNA polymerase family B alpha
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein uL10-like insertion
N-sulphoglucosamine sulphohydrolase C-terminal
Exocyst complex component Sec3 PIP2-binding N-terminal
Integrin alpha-2 domain-containing protein
TATA box binding protein associated factor (TAF) histone-like fold
Peptidase M1 membrane alanine aminopeptidase
Bicarbonate transporter-like transmembrane
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA-directed RNA polymerase subunit 2 hybrid-binding
cGMP-dependent protein kinase interacting
SAM-dependent methyltransferase TRM5/TYW2-type
Large ribosomal subunit protein uL30 N-terminal eukaryotes
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Deleted in malignant brain tumors 1 protein
Thioredoxin domain-containing protein 12
Apoptosis-antagonizing transcription factor C-terminal
Glycylpeptide N-tetradecanoyltransferase C-terminal
Glycylpeptide N-tetradecanoyltransferase N-terminal
Nuclear receptor-binding factor 2 C-terminal
von Hippel-Lindau disease tumour suppressor alpha
von Hippel-Lindau disease tumour suppressor beta
U3 small nucleolar RNA-associated protein 20 C-terminal
U3 small nucleolar RNA-associated protein 20 N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Tumor necrosis factor receptor superfamily member 6
Unique cartilage matrix-associated protein
Gamma tubulin complex component C-terminal
Gamma tubulin complex component protein N-terminal
Retinoblastoma-associated protein C-terminal
Retinoblastoma-associated protein N-terminal
Pro-opiomelanocortin/corticotropin ACTH central region
DNA polymerase alpha subunit B N-terminal
DNA polymerase alpha/delta/epsilon subunit B
ATPsynthase alpha/beta subunit N-terminal extension
Acylamino-acid-releasing enzyme N-terminal
Gamma-aminobutyric acid receptor subunit beta-4
Nitric oxide synthase-interacting protein zinc-finger
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Low-density lipoprotein receptor-related protein
Non-canonical purine NTP phosphatase/PRRC1
Small ribosomal subunit protein uS17 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Disintegrin and metalloproteinase domain-containing protein 9
Phosphatidylinositol-specific phospholipase C X
Phosphorylated adapter RNA export protein RNA-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Neuronal acetylcholine receptor subunit alpha-9
RZZ complex subunit KNTC1/ROD C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Chromosome passenger complex (CPC) protein INCENP N-terminal
Retinoic acid receptor responder protein 2
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Serine/threonine-protein kinase receptor
18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal
Protein phosphatase 1 regulatory subunit 21 N-terminal
Nuclear-interacting partner of ALK/Rsm1-like C-terminal
Platelet-derived growth factor (PDGF) family profile
Cerebral cavernous malformations 2 harmonin-homology
Translocon-associated protein subunit delta
3-beta hydroxysteroid dehydrogenase/isomerase
Casein kinase substrate phosphoprotein PP28
Ribose-phosphate pyrophosphokinase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
S100/CaBP-9k-type calcium binding subdomain
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sphingolipid delta4-desaturase N-terminal
Rab geranylgeranyltransferase alpha subunit insert-domain
Tetratricopeptide repeat protein 7 N-terminal
May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate
Fibronectin type-II domain-containing protein
FACT complex subunit Spt16 N-terminal lobe
Histone chaperone RTT106/FACT complex subunit SPT16-like middle
Anaphase-promoting complex subunit 4 long
Torsin-1A-interacting protein 1/2 AAA+ activator
Saccharopine dehydrogenase-like C-terminal
G-protein coupled receptors family 1 profile domain-containing protein
Leucine-rich repeat transmembrane neuronal protein 4
Mandelate racemase/muconate lactonizing enzyme C-terminal
Coatomer gamma subunit appendage Ig-like subdomain
Alpha galactosidase A C-terminal beta-sandwich
Pentacotripeptide-repeat region of PRORP
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Alpha-ketoglutarate-dependent dioxygenase AlkB-like
Cationic amino acid transporter C-terminal
Corticotropin-releasing factor-binding protein
Conserved oligomeric Golgi complex subunit 2 N-terminal
Mediator complex subunit Med13 C-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Pre-mRNA cleavage complex subunit Clp1 C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA replication complex GINS protein SLD5 C-terminal
NPC intracellular cholesterol transporter 2
Domain of unknown function with conserved HDNR motif
Schiff-base intermediate with substrate; via topaquinone
Voltage-gated Na+ ion channel cytoplasmic
Hyaluronan-mediated motility receptor C-terminal
Small ribosomal subunit protein uS4 N-terminal
Tubulin epsilon and delta complex protein 1
Insulin-like growth factor-binding protein 3
Copper type II ascorbate-dependent monooxygenase C-terminal
Copper type II ascorbate-dependent monooxygenase N-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal
Tryptophan synthase beta chain-like PALP
Ribosomal RNA-processing protein 7 C-terminal
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
Peptidoglycan recognition protein family
Transcription initiation factor IIA gamma subunit C-terminal
Transcription initiation factor IIA gamma subunit N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Ricin B lectin domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Transcription elongation factor Eaf N-terminal
Important for obstruction of the ion pore in the closed conformation
Myo-inositol-1-phosphate synthase GAPDH-like
Synaptonemal complex protein 2 Spt16M-like
Synaptonemal complex protein 2 armadillo-repeat-like
UDP-glucose:glycoprotein glucosyltransferase thioredoxin-like
UDP-glucuronate decarboxylase N-terminal
Ancestral coatomer element 1 Sec16/Sec31
Thiamin pyrophosphokinase thiamin-binding
'Ionic lock' involved in activated form stabilization
Plays an important role in the conformation switch to the active conformation
Fanconi anemia core complex-associated protein 24 pseudonuclease
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
NIF system FeS cluster assembly NifU N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Ribosomal RNA methyltransferase SPB1-like C-terminal
Gamma-secretase-activating protein C-terminal
DBC1/CARP1 catalytically inactive NUDIX hydrolase
Vacuolar protein 14 C-terminal Fig4-binding
AP-4 complex subunit epsilon-1 C-terminal
Important for autoinhibition of adenylyltransferase activity
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Dipeptidyl peptidase 4 low complexity region
Origin recognition complex subunit 3 N-terminal
Origin recognition complex subunit 3 insertion
Origin recognition complex subunit 3 winged helix C-terminal
Calcium-activated potassium channel BK alpha subunit
Nuclear speckle splicing regulatory protein 1 N-terminal
Nuclear speckle splicing regulatory protein 1 RS-like
U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein
Chromodomain-helicase-DNA-binding protein 1-like C-terminal
Cell division control protein 73 C-terminal
Protein inscuteable homologue C-terminal
Protein inscuteable homologue LGN-binding
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
G protein-regulated inducer of neurite outgrowth C-terminal
5-glutamyl coenzyme A thioester intermediate