G-protein coupled receptors family 1 profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Opioid growth factor receptor (OGFr) conserved
Histone deacetylase complex subunit SAP30 Sin3 binding
Histone deacetylase complex subunit SAP30 zinc-finger
Histone deacetylase complex subunit SAP30L-B
Important for DNA and phosphoinositide binding
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
G-protein coupled receptors family 3 profile
Doublesex- and mab-3-related transcription factor 1B
Interchain (with C-? in LTBP1 TB3 domain); in inactive form
Major facilitator superfamily (MFS) profile
Type I cytokine receptor cytokine-binding
E3 ubiquitin-protein ligase Arkadia N-terminal
Lamina-associated polypeptide 2 alpha C-terminal
Speedy/Ringo box; required for cdk-binding
von Willebrand factor A domain-containing protein 2
Inactive tyrosine-protein kinase transmembrane receptor ROR1
Abolishes mRNA-binding and cytoplasmic retention, localizing predominantly to the nucleus from early development. Also disrupts DNA-binding; when associated with A-433.
Abolishes mRNA-binding and cytoplasmic retention, localizing predominantly to the nucleus from early development. Also disrupts DNA-binding; when associated with A-552.
Proton-coupled zinc antiporter SLC30A9, mitochondrial
Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tryptophan synthase beta chain-like PALP
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Corticotropin-releasing factor receptor 1
G-protein coupled receptors family 2 profile 1
G-protein coupled receptors family 2 profile 2
General transcription factor IIF subunit 1
Insulin-like growth factor 1 receptor alpha chain
Insulin-like growth factor 1 receptor beta chain
Cytoplasmic activation/proliferation-associated protein-1 C term
SEC14 domain and spectrin repeat-containing protein 1-B
GRB2-associated and regulator of MAPK protein
Transcription factor CBF/NF-Y/archaeal histone
CDGSH iron-sulfur domain-containing protein 2B
C-terminal transmembrane transporter domain
Mitochondrial adenyl nucleotide antiporter SLC25A24-A
Abolished ability to mediate peroxisomal import of proteins.
Abolished monoubiquitination, leading to impaired ability to mediate peroxisomal import of proteins.
Does not affect ability to mediate peroxisomal import of proteins.
Glycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in ubiquitin)
Strogly reduced ability to mediate peroxisomal import of proteins; when associated with 112-A--A-119.
Strogly reduced ability to mediate peroxisomal import of proteins; when associated with 132-A--A-136.
Voltage-gated potassium channel subunit beta-3
Structural maintenance of chromosomes protein 4
ER membrane protein complex subunit 7 beta-sandwich
Microtubule-associated tumor suppressor 1 homolog
4 X 10 AA tandem repeats of G-[NS]-R-S-R-[AS]-[HQ]-T-[DGN]-[DET]
Neurotransmitter-gated ion-channel ligand-binding
Neurotransmitter-gated ion-channel transmembrane
Ran-GTPase activating protein 1 C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
TGF-beta family profile domain-containing protein
Electron transfer via tryptophanyl radical
Anaphase-promoting complex subunit 4-like WD40
Proprotein convertase subtilisin/kexin type 9
Proprotein convertase subtilisin/kexin type 9 C-terminal
Threonylcarbamoyladenosine tRNA methylthiotransferase
Protein phosphatase 1 regulatory subunit 21
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
For hydroxyacyl-coenzyme A dehydrogenase activity
Important for hydroxyacyl-coenzyme A dehydrogenase activity
Important for long-chain enoyl-CoA hydratase activity
Translocon-associated protein subunit alpha
DNA polymerase alpha catalytic subunit N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Zinc finger DNA-directed DNA polymerase family B alpha
Cation-transporting P-type ATPase N-terminal
Pancreas transcription factor 1 subunit alpha
Essential for stabilizing binding to COTL1
Histone-binding protein RBBP4 N-terminal
NF-kappa-B essential modulator NEMO CC2-LZ
Sulfatase N-terminal domain-containing protein
Negative regulator of microtubule-binding
Cationic amino acid transporter C-terminal
Required for transcriptional activity and interaction with ctnnb1
Significantly reduces transcriptional activation activity. Impairs interaction with ctnnb1.
Interferon-related developmental regulator C-terminal
Interferon-related developmental regulator N-terminal
Alpha 1,4-glycosyltransferase domain-containing protein
PiggyBac transposable element-derived protein
PiggyBac transposable element-derived protein 4 C-terminal zinc-ribbon
Aminoacyl-transfer RNA synthetases class-II family profile
Fibrinogen C-terminal domain-containing protein
tRNA-splicing endonuclease subunit Sen15
Inward rectifier potassium channel C-terminal
Potassium channel inwardly rectifying transmembrane
Pleckstrin homology domain-containing family M member 3
Zinc finger and BTB domain-containing protein 8A.1-A
Trimeric intracellular cation channel type B-A
U3 small nucleolar RNA-associated protein 20 C-terminal
U3 small nucleolar RNA-associated protein 20 N-terminal
Ubiquitin-activating enzyme E1 C-terminal
E3 ubiquitin-protein ligase RNF220 middle
Hyaluronan and proteoglycan link protein 3
Coiled-coil domain-containing protein 124-B
Rad21/Rec8-like protein C-terminal eukaryotic
Tumor necrosis factor receptor type 1-associated DEATH domain protein
TERF1-interacting nuclear factor 2 N-terminal
Eukaryotic glycogen debranching enzyme N-terminal
Glycogen debranching enzyme glucanotransferase
TATA box binding protein associated factor (TAF) histone-like fold
U2A'/phosphoprotein 32 family A C-terminal
Corticotropin-releasing factor domain-containing protein
V-set and immunoglobulin domain-containing protein 1
Olfactomedin-like domain-containing protein
Origin recognition complex subunit 3 N-terminal
Origin recognition complex subunit 3 insertion
Origin recognition complex subunit 3 winged helix C-terminal
S phase cyclin A-associated protein in the endoplasmic reticulum N-terminal
DRY motif; important for ligand-induced conformation changes
NPxxY motif; important for ligand-induced conformation changes and signaling
Shiftless antiviral inhibitor of ribosomal frameshifting protein homolog
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
N-acetyltransferase ESCO acetyl-transferase
Biopterin-dependent aromatic amino acid hydroxylase family profile
Inositol polyphosphate-related phosphatase
NADPH:adrenodoxin oxidoreductase, mitochondrial
eEF1A lysine and N-terminal methyltransferase
Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site
Janus kinase and microtubule-interacting protein C-terminal
DNA-directed DNA polymerase family B mitochondria/virus
39S ribosomal protein L39, mitochondrial
Helical; Signal-anchor for type II membrane protein
Serine/threonine specific protein phosphatases
RNA polymerase-associated protein CTR9 homolog
Enhancer of mRNA-decapping protein 4 WD40 repeat region
Necessary for homodimerization, competence for chromatin assembly
Inosine/uridine-preferring nucleoside hydrolase
von Willebrand factor D and EGF domain-containing protein
Glycosyl hydrolases family 22 (GH22) domain-containing protein
Pyrimidine nucleoside phosphorylase C-terminal
Potassium channel tetramerisation-type BTB
Abnormal spindle-like microcephaly-associated protein ASH
Homologous-pairing protein 2 winged helix
Osteopetrosis-associated transmembrane protein 1
Dynein heavy chain ATP-binding dynein motor region
Dynein heavy chain hydrolytic ATP-binding dynein motor region
U3 small nucleolar RNA-associated protein 13 C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Pseudouridine synthase I TruA alpha/beta
Loss of activity; no effect on RNA-binding.
Reduced activity; no effect on RNA-binding.
Strongly reduced activity; no effect on RNA-binding.
Myeloid differentiation primary response protein MyD88-B
Voltage-gated Na+ ion channel cytoplasmic
Corticotropin-releasing factor-binding protein
Sodium/hydrogen exchanger regulatory region
Hepatoma-derived growth factor-related protein 2
Guanylate kinase/L-type calcium channel beta subunit
Small ribosomal subunit protein uS15 N-terminal
Katanin p60 ATPase-containing subunit A-like 2
Protein transport protein Sec61 subunit gamma
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
G-patch domain and KOW motifs-containing protein
Saposin B-type domain-containing protein
Sodium/calcium exchanger membrane region
Cytochrome b5 heme-binding domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
Lysosome-associated membrane glycoprotein 2
G-protein coupled receptors family 1 profile domain-containing protein
DNA repair protein complementing XP-A cells homolog
Myo-inositol-1-phosphate synthase GAPDH-like
Peptidase M12B domain-containing protein
Methylthioribulose-1-phosphate dehydratase
Telomerase activating protein Est1-like N-terminal
Small ribosomal subunit protein uS4 N-terminal
G-protein coupled receptor-associated protein LMBRD2
S-adenosyl-L-homocysteine hydrolase NAD binding
SEC14 domain and spectrin repeat-containing protein 1-A
A; required for its colocalization with lamins at the nuclear envelope
BAF-binding site (BBS); essential for interaction with banf1-a, banf1-b and ran
Nuclear envelope integral membrane protein 1a
Peptidase S9 prolyl oligopeptidase catalytic
Mediator complex subunit Med13 C-terminal
Protein phosphatase 1 regulatory subunit 15A/B C-terminal
Negative regulator of reactive oxygen species
CCR4-NOT transcription complex subunit 10-B
MyoD family inhibitor domain-containing protein
Bicarbonate transporter-like transmembrane
V(D)J recombination-activating protein 2
Translation elongation factor IF5A C-terminal
HAUS augmin-like complex subunit 3 N-terminal
Ionotropic glutamate receptor C-terminal
Ionotropic glutamate receptor L-glutamate and glycine-binding
Xaa-Pro dipeptidyl-peptidase-like domain-containing protein
Multiple epidermal growth factor-like domains protein 8
POU domain, class 3, transcription factor 1-B
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
Non-structural maintenance of chromosome element 4 C-terminal
Transmembrane protein TMEM132 C-terminal
Transmembrane protein TMEM132 N-terminal
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8)
Polypeptide N-acetylgalactosaminyltransferase
Cocaine- and amphetamine-regulated transcript protein
Gamma tubulin complex component C-terminal
Gamma tubulin complex component protein N-terminal
Important for obstruction of the ion pore in the closed conformation
Calcium-activated potassium channel BK alpha subunit
Pleckstrin homology domain-containing family J member 1
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glutamine amidotransferase-like class 1 domain-containing protein 1
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Deleted in malignant brain tumors 1 protein
Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium
Galactose-1-phosphate uridyl transferase N-terminal
Major intrinsically disordered Notch2-binding receptor 1-like C-terminal
L-type lectin-like domain-containing protein
Embryonic polyadenylate-binding protein 2-A
DNA-directed RNA polymerase RBP11-like dimerisation
DNA-directed RNA polymerases I and III subunit RPAC2
Insulin-like growth factor-binding protein 1
CCR4-NOT transcription complex subunit 1
CCR4-NOT transcription complex subunit 1 CAF1-binding
CCR4-NOT transcription complex subunit 1 HEAT repeat
CCR4-NOT transcription complex subunit 1 TTP binding
CCR4-Not complex component Not1 C-terminal
Developmentally-regulated GTP-binding protein 1
Does not affect the microtubule-related activities, including binding and tubulin polymerization.
Vacuolar protein sorting-associated protein 54 N-terminal
Sulfotransferase domain-containing protein
Retinoic acid receptor responder protein 2
Spindle and centriole-associated protein 1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Telomere repeat-binding factor dimerisation
Iroquois-class homeodomain protein irx-4-A
Eukaryotic translation initiation factor 3 subunit D
Peptidase metallopeptidase domain-containing protein
Inhibits enzymatic activity. Induces duplication of the anterior dorsal axis.
Protein phosphatase 1 regulatory subunit 3C
CaM kinase-like vesicle-associated protein
Sodium-dependent phosphate transporter 1-B
Serine-threonine/tyrosine-protein kinase catalytic
Chemokine interleukin-8-like domain-containing protein
Somatostatin/Cortistatin C-terminal domain-containing protein
Phosphatidylserine amidated glycine; alternate
Aminoacyl-tRNA synthetase class I anticodon-binding
Serine/threonine-protein kinase pdik1l-A
DNA replication complex GINS protein SLD5
DNA replication complex GINS protein SLD5 C-terminal
Phosphatidylinositol-glycan-specific phospholipase D
Zinc finger protein 750-like zinc finger
Damage-control phosphatase ARMT1-like metal-binding
Vacuolar protein sorting-associated protein 26A-A
Intraflagellar transport protein 43 homolog
Zygotic DNA replication licensing factor mcm6-B
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
non-specific serine/threonine protein kinase
G protein-regulated inducer of neurite outgrowth C-terminal
Asymmetric dimethylarginine; by PRMT1; alternate
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate
N6-(2-hydroxyisobutyryl)lysine; alternate
Omega-N-methylarginine; by PRMT1; alternate
Symmetric dimethylarginine; by PRMT5 and PRMT7; alternate
Slightly decreases phosphorylation by CK2.
Bactericidal permeability-increasing protein
Lipid-binding serum glycoprotein C-terminal
Lipid-binding serum glycoprotein N-terminal
Telomere length regulation protein conserved
Platelet-derived growth factor (PDGF) family profile
Platelet-derived growth factor (PDGF) family profile domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Adenine-nucleotide binding in RNA target
Guanine-nucleotide binding in RNA target
Non-specific-nucleotide binding in RNA target
Bridge-like lipid transfer protein family member 1 C-terminal
receptor protein serine/threonine kinase
WLDD motif; essential for 7-methylguanosine-containing mRNA cap binding
Protein-S-isoprenylcysteine O-methyltransferase
Pre-rRNA-processing protein RIX1 N-terminal
Proline-, glutamic acid- and leucine-rich protein 1
Heterogeneous nuclear ribonucleoprotein A3 homolog 1
Potassium channel voltage dependent KCNQ C-terminal
Maternal DNA replication licensing factor mcm3
Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5
Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5
Zinc finger TRAF-type-containing protein 1-B
Putative transcription factor p65 homolog
FXYD domain-containing ion transport regulator
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Leucine-rich repeat flightless-interacting protein 2
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
Schwannomin interacting protein 1 C-terminal
Important for inositol polyphosphate binding
Xenotropic and polytropic retrovirus receptor 1 homolog
CSC1/OSCA1-like N-terminal transmembrane
WD repeat-containing and planar cell polarity effector protein fritz homolog
Large ribosomal subunit protein uL4 C-terminal
Myelin-associated neurite-outgrowth inhibitor
Uso1/p115-like vesicle tethering protein C-terminal
Vesicle tethering protein Uso1/P115-like head
Acidic leucine-rich nuclear phosphoprotein 32 family member B
Aspartate/homoserine dehydrogenase NAD-binding
Coiled-coil domain-containing protein 77
Retains neural-inducing activity but at reduced potency.
Fibronectin type-III domain-containing protein
NAD(P)(+)--arginine ADP-ribosyltransferase
Synaptonemal complex protein 2 Spt16M-like
Synaptonemal complex protein 2 armadillo-repeat-like
Large ribosomal subunit protein uL10-like insertion
Vacuolar protein sorting-associated protein 51 homolog
Cell division control protein 45 homolog
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate
SUMO-activating enzyme subunit 2 C-terminal
Ubiquitin/SUMO-activating enzyme ubiquitin-like
Cytoplasmic polyadenylation element-binding protein 1-B
Necessary for degradation by the proteasome
Necessary for interaction with microtubules and localization at the mitotic apparatus
Ribonuclease A-domain domain-containing protein
Serine/threonine-protein phosphatase 4 regulatory subunit 3
Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central
Small ribosomal subunit protein uS17 N-terminal
Endosome/lysosome-associated apoptosis and autophagy regulator family member 2
Bipartite nuclear localization signal; in isoform 2
MKI67 FHA domain-interacting nucleolar phosphoprotein-like
Mediates end-to-end attachment of dimers
Cystatin kininogen-type domain-containing protein
ADP-ribosylation factor-like protein 6-interacting protein 4
Hydroxysteroid dehydrogenase-like protein 2
Domain of unknown function with conserved HDNR motif
Glycoprotein hormone subunit beta domain-containing protein
Necessary for oligomerization and EDEN-dependent deadenylation
G-protein coupled receptors family 3 profile domain-containing protein
Nucleoside diphosphate-linked moiety X motif 6
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members
Does not induce t/bra expression; when associated A-728. Induces t/bra expression; when associated with E-728.
Induces t/bra expression; when associated with 662-CTC-664.
Inhibits t/bra expression and mesoderm induction.
Signal transducer and activator of transcription 3.1
amyloid beta (A4) precursor-like protein 2 S homeolog isoform 2
Tetratricopeptide repeat protein 7 N-terminal
Receptor-type tyrosine-protein phosphatase alpha
protein tyrosine phosphatase, receptor type A S homeolog
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Voltage-dependent calcium channel alpha-1 subunit IQ
Bardet-Biedl syndrome 12 protein homolog
Immunoglobulin-like domain-containing receptor 1
Protein prenyltransferase alpha subunit repeat-containing protein 1-A
Pericentriolar material 1 protein C-terminal
Self-association and localization to centrosomes
Interaction with galactose moiety of substrate glycoprotein
Actin-related protein 2/3 complex subunit 4
Leucine-rich repeat transmembrane protein FLRT3
Interaction with 5' end of substrate DNA
Acid sphingomyelinase-like phosphodiesterase
Sphingomyelin phosphodiesterase C-terminal
Collagen IV NC1 domain-containing protein
Phosphoribosyltransferase domain-containing protein 1
DDB1- and CUL4-associated factor 15 WD40 repeat-containing
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
KH domain-containing RNA-binding protein qki.L
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
C-terminal domain; mediates TORC1 regulation
Cysteine sulfenic acid (-SOH) intermediate
N-terminal domain; may mediate the alkylhydroperoxide reductase activity
Carnitine O-palmitoyltransferase N-terminal
UDP-N-acetylglucosamine transferase subunit ALG14 homolog
Neutral/alkaline non-lysosomal ceramidase C-terminal
Neutral/alkaline non-lysosomal ceramidase N-terminal
Glucagon / GIP / secretin / VIP family domain-containing protein
Protein arginine N-methyltransferase 1-A
Platelet-derived growth factor receptor alpha
Stabilizes the active site histidine for nucleophilic attack
DNA-(apurinic or apyrimidinic site) endonuclease 2
Failure to recruit of rpa2 and the checkpoint complex (atr, atrip, and rad9) onto damaged chromatin. Normal association with hydrogen peroxide-damaged chromatin.
Failure to recruit of rpa2 and the checkpoint complex (atr, trip, and rad9) onto damaged chromatin. Normal association with hydrogen peroxide-damaged chromatin.
Impaired binding to ssDNA. Abolished 3'-5' exonuclease activity in absence and presence of pcna. Does not impair endodeoxyribonuclease activity. Loss of hydrogen peroxide-induced chek1 phosphorylation. Failure to recruit rpa3, atr, atrip, and rad9 onto damaged chromatin.
Impaired binding to ssDNA. Impaired nucleolytic activity in the absence of pcna, but only reduced nucleolytic activity in presence of pcna.
Impaired binding to ssDNA. Impaired nucleolytic activity in the absence of pcna.
Loss of chek1 interaction. Loss of chek1 phosphorylation at Ser-344.
Loss of interaction with pcna. Loss of association with hydrogen peroxide-damaged chromatin. Failure to recruit rpa2 and the checkpoint complex (atr, atrip, and rad9) onto damaged chromatin. Loss of chek1 phosphorylation at Ser-344.
No impact on interaction with pcna. Impaired binding to ssDNA. Abolished 3'-5' exonuclease activity in absence of pcna, but only reduced 3'-5' exonuclease activity in presence of pcna.
Reduced interaction with pcna. Deficient in binding to ssDNA. Loss of SSB- or hydrogen peroxide-induced chek1 phosphorylation.
Reduced interaction with pcna. No impact on binding to ssDNA.
Reduced interaction with pcna. No impact on binding to ssDNA. Failure to recruit checkpoint proteins rpa2-a, atr, atrip, topbp1 and rad9a.L to DNA single strand breaks.
Transmembrane protein 127 transmembrane region
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Transcriptional coactivator p15 (PC4) C-terminal
Neuronal acetylcholine receptor subunit alpha-2
Dendritic cell-specific transmembrane protein-like
Phosphatidylinositol-glycan biosynthesis class X protein
V-type proton ATPase subunit S1/VOA1 transmembrane
Histone RNA hairpin-binding protein RNA-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Spliceosome-associated protein CWC27 homolog
LHFPL tetraspan subfamily member 3 protein
Nuclear distribution protein nudE-like 1-B
Endothelial differentiation-related factor 1 homolog
Hydroxysteroid 11-beta-dehydrogenase 1-like protein B
Endoplasmic reticulum vesicle transporter C-terminal
Endoplasmic reticulum vesicle transporter N-terminal
Endoplasmic reticulum-Golgi intermediate compartment protein 3
Pyridoxal-dependent decarboxylase domain-containing protein 1
Large ribosomal subunit protein uL23 N-terminal
Ubiquinol-cytochrome-c reductase complex assembly factor 3
Histone deacetylase glutamine rich N-terminal
RNA-binding protein with serine-rich domain 1-A
SHC SH2 domain-binding protein 1 homolog B
Sulfatase-modifying factor enzyme domain-containing protein
Plays an important role in the conformation switch to the active conformation
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase
Unique cartilage matrix-associated protein
U7 snRNA-associated Sm-like protein LSm11
Myb-related transcription factor, partner of profilin
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Axin interactor, dorsalization-associated protein A
Retinoblastoma-associated protein C-terminal
Retinoblastoma-associated protein N-terminal
RNA polymerase II-associated factor 1 homolog
Interaction with phosphoserine on interacting protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Almost completely abolishes suppression of secondary axis formation and organizer function, and disrupts ldb1 ubiquitination; when associated with A-591.
Almost completely abolishes suppression of secondary axis formation and organizer function, and disrupts ldb1 ubiquitination; when associated with A-594.
Exocyst complex component Sec3 PIP2-binding N-terminal
Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity
Abolishes phosphorylation by atm and atr preventing spindle assembly inactivation.
Copper type II ascorbate-dependent monooxygenase C-terminal
Copper type II ascorbate-dependent monooxygenase N-terminal
Protein arginine methyltransferase NDUFAF7, mitochondrial
Non-canonical purine NTP phosphatase/PRRC1
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit B
Neurogenic locus notch homolog protein 3
BLOC-2 complex member HPS3 central region
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
CBY1-interacting BAR domain-containing protein 1-A
Hyaluronan and proteoglycan link protein 1
Doublesex- and mab-3-related transcription factor DM-W
E3 ubiquitin-protein ligase synoviolin B
Mediator of RNA polymerase II transcription subunit 4
Zygotic DNA replication licensing factor mcm3
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Sperm-specific basic nuclear protein SP4
Mitochondrial import inner membrane translocase subunit Tim9
Short myomegalin-like EB1 binding protein N-terminal
Ciliogenesis and planar polarity effector 2
Loss of localization to the cilium basal body. Dominant negative form altering cilium biogenesis.
Release factor glutamine methyltransferase N-terminal
Interleukin-17 receptor fibronectin-III-like
Charged multivesicular body protein 2b-B
Dominant-negative mutant; reduces the level of cdk1 tyrosine phosphorylation and shortened the length of the cell cycle.
Strongly reduces the interaction with cdca3.
Heterogeneous nuclear ribonucleoprotein D-like-B
Baculoviral IAP repeat-containing protein 5.2-B
Reduces ATPase activity of the mcm2-mcm7 complex and disrupts DNA replication. Does not disrupt formation of the pre-replicative complex onto chromatin. Abolishes ATPase activity of the mcm2-mcm7 complex; when associated with A-404 in mmcm6.
Superoxide dismutase copper/zinc binding
AJAP1/PANP C-terminal domain-containing protein
Spindle and kinetochore-associated protein 3
FAD-dependent oxidoreductase domain-containing protein 2
Natural cytotoxicity triggering receptor 3
Isochorismatase domain-containing protein 2
Eukaryotic translation initiation factor 3 subunit K
Probable tRNA (uracil-O(2)-)-methyltransferase
Proteasome activator complex subunit 4 C-terminal
Glial cell line-derived neurotrophic factor
A disintegrin and metalloproteinase with thrombospondin motifs 2
POU domain, class 5, transcription factor 1.1
Glucose-methanol-choline oxidoreductase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA-directed DNA polymerase family A palm
Baculoviral IAP repeat-containing protein 5.1-B
Mitochondrial import inner membrane translocase subunit Tim13-A
Ubiquitin carboxyl-terminal hydrolase 20
SAPK-interacting protein 1 Pleckstrin-homology
NAD-dependent protein deacylase sirtuin-5A, mitochondrial
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
Sufficient for localization to Golgi membrane
Tyrosinase copper-binding domain-containing protein
Exocyst complex subunit Sec15 C-terminal
Exocyst complex component Sec8 N-terminal
GPR180/TMEM145 transmembrane domain-containing protein
Telomeric single stranded DNA binding POT1/Cdc13
Voltage-dependent calcium channel alpha-2/delta subunit conserved region
Chromosome passenger complex (CPC) protein INCENP N-terminal
Mitochondrial coenzyme A transporter SLC25A42
R-spondin Fu-CRD domain-containing protein
Dickkopf N-terminal cysteine-rich domain-containing protein
Fanconi anemia complex subunit FancL WD-repeat containing
Peptidase M14 carboxypeptidase A domain-containing protein
Glutamate receptor-interacting protein 2
Zinc finger CCCH-type with G patch domain-containing protein
Serine/threonine-protein kinase receptor
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein
SUEL-type lectin domain-containing protein
Trafficking kinesin-binding protein C-terminal
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
Protein kinase domain-containing protein
Ciliated left-right organizer metallopeptidase
Cytosolic Fe-S cluster assembly factor nubp1-A
Mediator of RNA polymerase II transcription subunit 22
UDP-glucose:glycoprotein glucosyltransferase 2
UDP-glucose:glycoprotein glucosyltransferase thioredoxin-like
Important for transcriptional activation
Endoplasmic reticulum resident protein 29
Endoplasmic reticulum resident protein 29 C-terminal
Insulin-like growth factor 2 mRNA-binding protein 3-B
26 X 10 AA approximate tandem repeats of [DE]-[DE]-[DE]-R-[GTV]-[PS]-R-R-G-[AFGLM]
Eukaryotic translation initiation factor 3 subunit A
Ubiquitin carboxyl-terminal hydrolase 22-B
Tubulin epsilon and delta complex protein 1
Chromatin target of PRMT1 protein C-terminal
MDS1 and EVI1 complex locus protein EVI1-B
Important for cleavage of target proteins
Iroquois-class homeodomain protein irx-1-B
Translocon-associated protein subunit delta
signal sequence receptor, delta L homeolog
Store-operated calcium entry-associated regulatory factor
ER membrane protein complex subunit 1 C-terminal
NF-kappa-B-activating protein C-terminal
Embryonic polyadenylate-binding protein A
POU domain, class 2, transcription factor 3L
Abolishes phosphorylation by GWL and ability to regulate mitosis.
Segment polarity protein dishevelled homolog DVL-3
Intraflagellar transport protein 20 homolog B
DNA replication complex GINS protein PSF1
Beta-adaptin appendage C-terminal subdomain
Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain
Trafficking protein particle complex subunit 11
Trafficking protein particle complex subunit 11 C-terminal
Mitochondrial cytochrome c oxidase subunit VIc/VIIs
Actin-related protein 2/3 complex subunit 2-A
VTT domain; required for its function in autophagy
A-kinase anchor protein 7-like phosphoesterase
Important for regulated proteolytic degradation
Reduces regulated proteolytic degradation.
Sorting and assembly machinery component 50 homolog B
Ubiquitin-like modifier-activating enzyme 5
Ubiquinone biosynthesis protein COQ9-B, mitochondrial
Loss of function due to disruption of the EDM complex.
Interaction with U4 snRNA and U4atac snRNA
Reverse transcriptase/retrotransposon-derived protein RNase H-like
Glycine cleavage T-protein C-terminal barrel
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Bridge-like lipid transfer protein family member 3B
8 X 9 AA approximate tandem repeat of [AP]-P-G-G-P-Y-G-G-P-P
Micro-fibrillar-associated protein 1 C-terminal
DNA polymerase alpha/delta/epsilon subunit B
Guanine nucleotide-binding protein G(q) subunit alpha
Does not affect ability to restore translation to an EIF4E-dependent in vitro translation system. Does not affect efficient EIF4E-mediated promotion of EIF4G cleavage by L-protease.
Eukaryotic translation initiation factor 4E
Cleavage and polyadenylation specificity factor subunit 2
Serine/threonine-protein phosphatase 6 regulatory subunit 3-B
Cysteine-rich DPF motif domain-containing protein 1
Eukaryotic peptide chain release factor subunit 1
NIKS motif; plays an important role in translational termination
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
AP-4 complex subunit epsilon-1 C-terminal
Ribosomal RNA methyltransferase SPB1-like C-terminal
Arginine vasopressin-induced protein 1/transcriptional and immune response regulator
Required for the recognition of 25-hydroxycholesterol
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for recycling of cargo proteins with the sequence motif K-D-E-L from the Golgi to the endoplasmic reticulum
Interaction with the K-D-E-L motif on target proteins
Sigma non-opioid intracellular receptor 1
Chromosome segregation protein Spc25 C-terminal
Nuclear distribution protein nudE homolog 1-A
Vacuolar protein sorting-associated protein 41 homolog
Potassium channel inwardly rectifying Kir N-terminal
Glycylpeptide N-tetradecanoyltransferase C-terminal
Glycylpeptide N-tetradecanoyltransferase N-terminal
BMP and activin membrane-bound inhibitor C-terminal
BMP and activin membrane-bound inhibitor N-terminal
BMP and activin membrane-bound inhibitor homolog
Low-density lipoprotein receptor-related protein
Microtubule-associated protein RP/EB family member 2
Tumor necrosis factor alpha-induced protein 8-like protein 2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter C-terminal
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Vesicular inhibitory amino acid transporter
Fragile X messenger ribonucleoprotein 1 homolog B
Proline-rich nuclear receptor coactivator 2 B
Repressor of RNA polymerase III transcription MAF1 homolog
Myocyte-specific enhancer factor 2D homolog
Transducer of regulated CREB activity C-terminal
Transducer of regulated CREB activity N-terminal
Transducer of regulated CREB activity middle
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
TP53-regulated inhibitor of apoptosis 1-A
Neuronal acetylcholine receptor subunit alpha-4
6-phosphogluconate dehydrogenase C-terminal
Sushi, nidogen and EGF-like domain-containing protein 1
Prion/Doppel protein beta-ribbon domain-containing protein
Mab-21-like HhH/H2TH-like domain-containing protein
Important for autoinhibition of adenylyltransferase activity
Cytosolic Fe-S cluster assembly factor nubp2
Interferon regulatory factor 2-binding protein-like B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
'Ionic lock' involved in activated form stabilization
Near loss of rhodopsin accumulation in rod outer segments.
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
POU domain, class 3, transcription factor 4-A
Nucleolar and spindle-associated protein 1-A
Alpha/beta hydrolase fold-3 domain-containing protein
Platelet-derived growth factor C, receptor-binding form
Helical; Voltage-sensor; Name=Segment S4
Potassium voltage-gated channel subfamily KQT member 1
Piezo non-specific cation channel R-Ras-binding
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Microtubule-associated serine/threonine-protein kinase 3
von Willebrand factor A domain-containing protein 1
GPI ethanolamine phosphate transferase 2 C-terminal
Telomere-associated protein Rif1 N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Serine/threonine/tyrosine-interacting protein A
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Schiff-base intermediate with substrate; via topaquinone
LHFPL tetraspan subfamily member 6 protein
Essential for phosphatidylinositol-4-phosphate phosphatase activity
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Protein kinase C and casein kinase substrate in neurons protein 2
Sister chromatid cohesion protein PDS5 homolog B-A
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial
7 X 7 AA approximate repeats of [TS]-E-L-C-R-[AP]-P
T-cell acute lymphocytic leukemia protein 1
Multiple myeloma tumor-associated protein 2-like N-terminal
SH3 and multiple ankyrin repeat domains protein 2
Eukaryotic translation initiation factor 3 subunit G-A
Thrombospondin type-1 domain-containing protein 1
Mitochondrial amidoxime-reducing component 1
Vasoactive intestinal polypeptide receptor 1
Trichoplein keratin filament-binding protein
RNA polymerase subunit H/Rpb5 C-terminal
Guanine nucleotide-binding protein subunit alpha-11
Centriolar and ciliogenesis-associated protein HYLS1 C-terminal
Schiff-base intermediate with acetaldehyde
Ciliary neurotrophic factor receptor subunit alpha
Dual serine/threonine and tyrosine protein kinase
Formiminotransferase N-terminal subdomain
Kringle-containing protein marking the eye and the nose
Glycoside hydrolase family 31 N-terminal
Nascent polypeptide-associated complex subunit alpha-like UBA
A kinase-anchoring proteins AKAP-5 and AKAP-12 calmodulin (CaM)-binding
3-beta hydroxysteroid dehydrogenase/isomerase
Disintegrin and metalloproteinase domain-containing protein 12
Cytoskeleton-associated protein 2 C-terminal
Ancestral coatomer element 1 Sec16/Sec31
Cilia- and flagella-associated protein 36
Translocon-associated protein subunit beta
Nucleoporin Nup133/Nup155-like C-terminal
Nucleoporin Nup133/Nup155-like N-terminal
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
Guided entry of tail-anchored proteins factor 1
Natural killer cell receptor 2B4 immunoglobulin
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Decreased formation of basal bodies in multiciliated cells.
Mediator of RNA polymerase II transcription subunit 30
Abolished binding to the 3'-UTR of mRNAs.
F-box-like/WD repeat-containing protein TBL1XR1-B
Nuclear speckle splicing regulatory protein 1 N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Palmitoleoyl-protein carboxylesterase notum1
Transcription elongation factor Eaf N-terminal
Oxidized purine nucleoside triphosphate hydrolase
RNA-polymerase II-associated protein 3-like C-terminal
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A
Mitochondrial apoptosis-inducing factor C-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Pre-mRNA cleavage complex subunit Clp1 C-terminal
Neurogenic locus notch homolog protein 1
Large ribosomal subunit protein uL6 N-terminal
Chemokine binding, important for signaling
Important for chemokine binding and signaling
Involved in dimerization; when bound to chemokine
AB hydrolase-1 domain-containing protein
D-ribitol-5-phosphate cytidylyltransferase C-terminal
Notch-regulated ankyrin repeat-containing protein
Abolished ability to mediate ubiquitination of mcm7.
Does not affect ability to mediate ubiquitination of mcm7.
Impaired ability to mediate ubiquitination of mcm7. Abolished ability to promote ubiquitination of covalent DNA-protein cross-links (DPCs).
Essential for homodimerization and microtubule bundling activity
EF-hand calcium-binding domain-containing protein 7
Phosphatidylinositol-specific phospholipase C X
Tumor necrosis factor-inducible gene 6 protein
Ribosomal RNA-processing protein 7 C-terminal
Tumor necrosis factor receptor superfamily member 6
Exocyst complex component EXOC2/Sec5 N-terminal
Mitogen-activated protein kinase kinase kinase 13-B
Transmembrane protein 131-like N-terminal
Transmembrane protein 131-like conserved
Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal
Intron-binding protein aquarius N-terminal
S100/CaBP-9k-type calcium binding subdomain
Actin interacting protein 3-like C-terminal
Cyclin-dependent kinases regulatory subunit 2
Probable cysteine--tRNA ligase, mitochondrial
Glycosyl transferase family 28 C-terminal
Uncharacterized protein C16orf52 homolog B
Nuclear receptor-interacting protein 1 repression
Membrane insertase YidC/Oxa/ALB C-terminal
Peptidoglycan recognition protein family
Guanine nucleotide-binding protein G(s) subunit alpha
Transforming growth factor beta-1-induced transcript 1 protein
Glycosyltransferase 8 domain-containing protein 1
Peptide methionine sulphoxide reductase MsrA
Cleavage; by procollagen C-endopeptidase
Cleavage; by procollagen N-endopeptidase
Mediator of RNA polymerase II transcription subunit 19
Abolishes threonine phosphorylation; when associated with S-260. No effect on phosphatase activity and MAPK1 binding; when associated with S-260.
Dual specificity protein phosphatase 1-A
Loss of phosphatase activity. Increases stability. Enables stable complex formation with active MAPK1. Abolishes threonine phosphorylation; when associated with E-168 or V-168. No effect on phosphatase activity and MAPK1 binding; when associated with E-168 or V-168.
Cleavage stimulation factor subunit 1 dimerisation
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
Ciliary BBSome complex subunit 2 C-terminal
Ciliary BBSome complex subunit 2 N-terminal
Ciliary BBSome complex subunit 2 middle region
Transmembrane protein 11-A, mitochondrial
Leucine-rich repeat-containing protein 57
D-box that targets the protein for proteasomal degradation in anaphase
Important for interaction with phosphorylated proteins
Prolyl-tRNA synthetase associated domain-containing protein 1
Rapamycin-insensitive companion of mTOR N-terminal
Rapamycin-insensitive companion of mTOR middle
Mesoderm induction early response protein 1
Cleavage/polyadenylation specificity factor A subunit C-terminal
Cleavage/polyadenylation specificity factor A subunit N-terminal
Translation initiation factor beta propellor-like
Plasma membrane calcium transporting P-type ATPase C-terminal
Mitochondrial adenyl nucleotide antiporter SLC25A24-B
Sphingolipid delta4-desaturase N-terminal
Protein phosphatase 1 regulatory subunit 26
Protein phosphatase 1 regulatory subunit 26 N-terminal
Asymmetric dimethylarginine; by CARM1; alternate
Asymmetric dimethylarginine; by PRMT6; alternate
Symmetric dimethylarginine; by PRMT5; alternate
Serine/threonine-protein phosphatase PGAM5, mitochondrial
Nerve growth factor-related domain-containing protein
Prenylcysteine lyase domain-containing protein
Elongation factor 1 beta central acidic region eukaryote
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Chromatin modification-related protein MEAF6
Inter-alpha-trypsin inhibitor heavy chain H5
Formiminotransferase C-terminal subdomain
Interaction with phosphoinositide-3 kinase
Sodium/potassium-transporting ATPase subunit alpha-1
Tyrosine-protein kinase transmembrane receptor ROR2
Lipocalin/cytosolic fatty-acid binding domain-containing protein
Neural chondroitin sulphate proteoglycan cytoplasmic
cGMP-dependent protein kinase interacting
Important for integrin interaction and activation
TYRO protein tyrosine kinase-binding protein
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1)
Involved in proton transfer during cleavage
Serine palmitoyltransferase small subunit A-B
Within the serine palmitoyltransferase (SPT) complex, defines the length of the acyl chain-binding pocket, determining the acyl-CoA substrate preference
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp
Inositol-tetrakisphosphate 1-kinase N-terminal
BLOC-1-related complex subunit 6 C-terminal helix
AT-rich interactive domain-containing protein 3A
Nucleoside diphosphate-linked moiety X motif 17
Mediator of RNA polymerase II transcription subunit 8-B
Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel
Sodium/potassium-transporting ATPase subunit gamma
Katanin p80 WD40 repeat-containing subunit B1
Zinc finger and BTB domain-containing protein 18.2
Spermatogenesis-associated protein 6 N-terminal
Required for phosphatidylinositol 4,5-bisphosphate-dependent location at the cell membrane
Retroviral integration site protein Fli-1 homolog
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
DNA polymerase alpha subunit B N-terminal
Coiled-coil SMC6 And NSE5 INteracting (CANIN)
Glycosyl transferase CAP10 domain-containing protein
In TR-alpha II; 3-fold reduction in triiodothyronine (T3)-binding activity.
In TR-alpha V; severe reduction in DNA binding and transcriptional activation.
In TR-alpha VII; abolishes DNA binding and reduces transcriptional activation.
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
FHF complex subunit HOOK interacting protein 2A
Zinc finger and BTB domain-containing protein 8A.1-B
Adenomatous polyposis coli N-terminal dimerisation
Adenomatous polyposis coli protein basic
Insulin-like growth factor-binding protein 2
Single-stranded DNA-binding protein 1-A, mitochondrial
Pentatricopeptide repeat-containing protein 2, mitochondrial
Gfo/Idh/MocA-like oxidoreductase N-terminal
Chromosome segregation in meiosis protein 3
Pre-B-cell leukemia transcription factor 1
Little elongation complex subunit 2 C-terminal
RecQ-mediated genome instability protein 1
Inhibits its targeting to microtubule minus ends.
Necessary for its targeting to microtubule minus ends
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Mitotic spindle assembly checkpoint protein MAD2B
O-linked (GalNAc...) threonine; alternate
Large ribosomal subunit protein uL15/eL18
Lysosome-associated membrane glycoprotein 5
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
Cyclic AMP-responsive element-binding protein 3-like protein 2
Processed cyclic AMP-responsive element-binding protein 3-like protein 2
Spo11/DNA topoisomerase VI subunit A N-terminal
Thiamin pyrophosphokinase thiamin-binding
Embryonic polyadenylate-binding protein 2-B
Nuclear receptor subfamily 2 group E member 1
Fucolectin tachylectin-4 pentraxin-1 domain-containing protein
7-methylguanosine phosphate-specific 5'-nucleotidase B
DNA-directed RNA polymerase I subunit RPA49
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cysteine/serine-rich nuclear protein N-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Glycoside hydrolase family 65 central catalytic
Hairy/enhancer-of-split related with YRPW motif protein 1
Necessary and sufficient for homooligomerization and localization to centrosomes and pericentriolar satellites
Prealbumin-like fold domain-containing protein
RNA N6-adenosine-methyltransferase mettl16
Disintegrin and metalloproteinase domain-containing protein 9
B-cell CLL/lymphoma 7 protein family member A
POU domain, class 3, transcription factor 1-A
Methionyl-tRNA synthetase anticodon-binding
Mannose-1-phosphate guanyltransferase beta-A
Ribosomal RNA adenine methylase transferase N-terminal
Arginine/serine-rich coiled-coil protein 2
Choloylglycine hydrolase/NAAA C-terminal
Abolishes binding to 5'-ATTGTT-3' DNA sequence.
Abolishes binding to 5'-ATTGTT-3' DNA sequence. Does not affect ctnnb1-binding.
Abolishes binding to 5'-ATTGTT-3' DNA sequence. Reduces binding to the nodal5 promoter. Does not affect ctnnb1-binding.
Does not abolish binding to 5'-ATTGTT-3' DNA sequence.
Mediator of RNA polymerase II transcription subunit 26
CDK-activating kinase assembly factor MAT1
Abolished binding to the 3'-UTR of mRNAs; when associated with A-190.
Abolished binding to the 3'-UTR of mRNAs; when associated with A-217.
Failed axon connections homolog N-terminal
Peptidase C19 ubiquitin carboxyl-terminal hydrolase
DNA polymerase subunit gamma-2, mitochondrial
GATOR complex protein MIO zinc-ribbon like
Large ribosomal subunit protein uL6 alpha-beta
Eukaryotic translation initiation factor 3 subunit E-A
CCR4-Not complex component Not N-terminal
Tartrate-resistant acid phosphatase type 5
Interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog A
ATP synthase subunit C lysine N-methyltransferase
RNA 3'-terminal phosphate cyclase insert
Clathrin/coatomer adaptor adaptin-like N-terminal
Coatomer gamma subunit appendage Ig-like subdomain
Iroquois-class homeodomain protein irx-4-B
Mediator of RNA polymerase II transcription subunit 15
Transcription and mRNA export factor ENY2
Oocyte-specific histone RNA stem-loop-binding protein 2
RNA polymerase II subunit A C-terminal domain phosphatase SSU72
Sodium-dependent phosphate transporter 1-A
Gamma-aminobutyric acid type B receptor subunit 1
Receptor ligand binding region domain-containing protein
Peptidase M10A matrix metallopeptidase C-terminal
Harmonin-binding protein USHBP1 PDZ-binding
Nuclear receptor-binding factor 2 C-terminal
Group XIIB secretory phospholipase A2-like protein
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
NEDD8-activating enzyme E1 regulatory subunit
Mitochondrial intermembrane space import and assembly protein 40-B
Coiled-coil domain-containing protein 85C
Pentacotripeptide-repeat region of PRORP
Pentacotripeptide-repeat region of PRORP domain-containing protein
Integrin alpha-2 domain-containing protein
Transcription factor IIIC 90kDa subunit N-terminal
Transcription factor IIIC putative zinc-finger
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
N-sulphoglucosamine sulphohydrolase C-terminal
Cilia- and flagella-associated protein 298-A
Transcription factor TFIIIC triple barrel
Histone-arginine methyltransferase CARM1
Histone-arginine methyltransferase CARM1 N-terminal
Uncharacterized protein KIAA1143 homolog
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Fanconi anaemia group A protein N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
N-terminal Xaa-Pro-Lys N-methyltransferase 1-A
Spermatogenesis-associated protein 1 C-terminal
Acylamino-acid-releasing enzyme N-terminal
Electron transfer flavoprotein beta subunit lysine methyltransferase
Peroxisome membrane anchor protein Pex14p N-terminal
Heterogeneous nuclear ribonucleoprotein A3 homolog 2
T-cell surface glycoprotein CD3 epsilon chain
Short-chain dehydrogenase/reductase family 42E member 1
Intraflagellar transport protein 57 homolog
Structural maintenance of chromosomes protein 2
DET1- and DDB1-associated protein 1 N-terminal
MD-2-related lipid-recognition domain-containing protein
Endoplasmic reticulum-Golgi intermediate compartment protein 1
KH domain-containing RNA-binding protein qki.S
Fibrinogen C domain-containing protein 1-B
Prokaryotic-type class I peptide chain release factors
Phosphatidylinositol glycan anchor biosynthesis class U protein
DNA mismatch repair proteins mutS family
Dominant negative that inhibits vangl2-B function.
Metallo-beta-lactamase domain-containing protein
High-affinity lysophosphatidic acid receptor
Saposin A-type domain-containing protein
Tumor necrosis factor receptor superfamily member 1A
Di-leucine motif; mediates lysosomal localization
Solute carrier family 49 member 4 homolog
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Platelet-derived growth factor receptor-like protein
Phosphatidylethanolamine-binding protein 4
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Influenza virus NS1A-binding protein homolog
ATP-grasp fold succinyl-CoA synthetase-type
Pericentrin/AKAP-450 centrosomal targeting
FGGY carbohydrate kinase domain-containing protein
Acyl-CoA-binding domain-containing protein 5
Mannose-1-phosphate guanyltransferase alpha-B
N-alpha-acetyltransferase 38-A, NatC auxiliary subunit
Complete loss of activity to induce the Wnt target gene Siamois expression.
Potassium voltage-gated channel subfamily D member 2
Almost completely abolishes the enzymatic activity.
Reduces the enzymatic activity to about 15% of that of the wild type.
Reduces the enzymatic activity to about 20% of that of the wild type.
Reduces the enzymatic activity to about 25% of that of the wild type.
Reduces the enzymatic activity to about 35% of that of the wild type.
Reduces the enzymatic activity to about 45% of that of the wild type.
Reduces the enzymatic activity to about 55% of that of the wild type.
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Calcium-binding and coiled-coil domain-containing protein 1-B
CBF1-interacting co-repressor CIR N-terminal
Vacuolar protein sorting-associated protein 72 homolog
Coiled-coil domain-containing protein 134
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Actin-related protein 2/3 complex subunit 5-A
Peptidase S8/S53 domain-containing protein
Cytochrome b5 domain-containing protein 1
5-glutamyl glycerylphosphorylethanolamine
Secretory carrier-associated membrane protein 5B
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
Serine/threonine-protein phosphatase 4 regulatory subunit 3-A
BTB/POZ domain-containing protein kctd15
Mandelate racemase/muconate lactonizing enzyme C-terminal
Mitochondrial enolase superfamily member 1
Parathyroid hormone/parathyroid hormone-related peptide receptor
Sodium-coupled neutral amino acid transporter 7
26S proteasome regulatory subunit RPN2 C-terminal
Pre-rRNA-processing protein Ipi1 N-terminal
Fibronectin type-II domain-containing protein
Major facilitator superfamily associated
Major facilitator superfamily domain-containing protein 6-like protein B
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Histone-lysine N-trimethyltransferase SMYD5
Fat storage-inducing transmembrane protein 1
Thioredoxin domain-containing protein 12
Adaptive response protein AidB N-terminal
Thioredoxin-related transmembrane protein 2
Multiple epidermal growth factor-like domains protein 6
Helical; Anchor for type IV membrane protein
Abolishes transcriptional repressive activity towards GATA.
Glyceraldehyde-3-phosphate dehydrogenase
Hydroxysteroid 11-beta-dehydrogenase 1-like protein A
Trimeric intracellular cation channel type A
Mediator of RNA polymerase II transcription subunit 7-A
Post-GPI attachment to proteins factor 3
Charged multivesicular body protein 2b-A
Serine/threonine-protein phosphatase 1 regulatory subunit 10
ATP synthase F1 complex delta/epsilon subunit N-terminal
WD repeat domain phosphoinositide-interacting protein 3
Torsin-1A-interacting protein 1/2 AAA+ activator
Large ribosomal subunit protein uL2 C-terminal
Iron-responsive element-binding protein 2
Probable E3 ubiquitin-protein ligase makorin-1
Methenyltetrahydrofolate synthase domain-containing protein
Multiprotein bridging factor 1 N-terminal
Fumarylacetoacetate hydrolase domain-containing protein 2
Calcineurin-binding protein cabin-1 MEF2-binding
SHC SH2 domain-binding protein 1 homolog A
Complex I assembly factor TIMMDC1, mitochondrial
GATA zinc finger domain-containing protein 1
Glucosamine/galactosamine-6-phosphate isomerase
Src kinase-associated phosphoprotein 2-B
Transcription initiation factor TFIID subunit 8
Nitric oxide synthase-interacting protein
Nitric oxide synthase-interacting protein zinc-finger
Breast cancer anti-estrogen resistance protein 3 homolog
Nuclear nucleic acid-binding protein C1D
RNA polymerase II-associated protein 1 C-terminal
RNA polymerase II-associated protein 1 N-terminal
GPI ethanolamine phosphate transferase 1 C-terminal
Regulator of G-protein signaling 7-binding protein
Impairs the ability of the C-terminal fragment to block nuclear pore assembly.
Sufficient to block nuclear pore assembly
Mitochondrial import inner membrane translocase subunit Tim13-B
Important for interaction with membranes
Phosphatidylinositol 4-kinase type 2-alpha
Collagen triple helix repeat-containing protein 1
DNA-directed RNA polymerase I subunit RPA2
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Required for ubiquitin ligase activity and for protection against ER stress-induced cell death
Protein-arginine deiminase (PAD) N-terminal
Protein-arginine deiminase (PAD) central
Peptidyl-prolyl cis-trans isomerase FKBP1A
WD repeat domain phosphoinositide-interacting protein 4
Transcription initiation factor IIA gamma subunit C-terminal
Transcription initiation factor IIA gamma subunit N-terminal
Signal peptide, CUB and EGF-like domain-containing protein 2
Inhibitor of nuclear factor kappa-B kinase subunit alpha
SPARC-related modular calcium-binding protein 1
Mediator of RNA polymerase II transcription subunit 23
Negatively regulates transcriptional activity
Ubiquitin carboxyl-terminal hydrolase 22-A
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Baculoviral IAP repeat-containing protein 5.1-A
Mimics phosphorylation but still inhibits spindle assembly.
NAD-dependent protein deacylase sirtuin-5B, mitochondrial
Amiloride-sensitive sodium channel subunit beta-2
tRNA N6-adenosine threonylcarbamoyltransferase
Iroquois-class homeodomain protein irx-2
Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Hormonally up-regulated neu tumor-associated kinase homolog A
Alpha/beta hydrolase domain-containing protein 17B
UDP-glycosyltransferases domain-containing protein
POU domain, class 2, transcription factor 3S
Discoidin, CUB and LCCL domain-containing protein 2
Disrupts DNA-binding. Unable to repress id3 transcription. Disrupts the ability to promote cell survival and up-regulate neural border genes. Does not disrupt the ability to promote cell proliferation and neural crest cell formation.
IGFBP N-terminal domain-containing protein
Actin-related protein 2/3 complex subunit 2-B
Eukaryotic translation initiation factor 5A-1
Breast cancer metastasis-suppressor 1-like protein
Ubiquitin-like domain-containing CTD phosphatase 1
RNA-binding protein with multiple splicing 2
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Histone-lysine N-methyltransferase KMT5B-B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Interleukin-1 receptor accessory protein
Immunoglobulin V-set domain-containing protein
Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Hydroxyacid-oxoacid transhydrogenase, mitochondrial
FHF complex subunit HOOK-interacting protein C-terminal
Protein phosphatase 1 regulatory subunit 3B-A
Putative gastrointestinal growth factor xP4
Loss of glycosylation. Prevents secretion. No effect on wnt5a-binding.
Loss of sulfation. No effect on secretion or homodimerization but severely reduces interaction with wnt5a and canonical Wnt signaling activity; when associated with F-274.
Loss of sulfation. No effect on secretion or homodimerization but severely reduces interaction with wnt5a and canonical Wnt signaling activity; when associated with F-281.
Programmed cell death protein 2 C-terminal
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
N-acetylglucosaminylphosphatidylinositol deacetylase
Bromodomain adjacent to zinc finger domain protein 2A
Actin, alpha cardiac muscle 1, intermediate form
N-acetylaspartate; in Actin, alpha cardiac muscle 1
SH3 domain-binding glutamic acid-rich-like protein 2-A
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
TOX high mobility group box family member 4-B
Eliminates one of two sumoylated products.
Eliminates one of two sumoylated products. Abolishes interaction with sumoylation factors.
DNA replication complex GINS protein PSF2
Hyaluronan-mediated motility receptor C-terminal
Oncoprotein-induced transcript 3 protein
Does not induce protein accumulation. Does not stimulate neurogenic activity. Does not alter subcellular localization; when associated with A-266 and A-274.
Induces protein accumulation. Stimulates ectopic neurogenic activity. Does not alter subcellular localization; when associated with A-258 and A-266.
Induces protein accumulation. Stimulates ectopic neurogenic activity. Does not alter subcellular localization; when associated with A-258 and A-274.
Promotes the formation of differentiated early retinal ganglion cells.
Hematopoietically-expressed homeobox protein hhex
Zinc finger C2HC domain-containing protein 1A
Histone acetyl transferase HAT1 N-terminal
Rab3 GTPase-activating protein catalytic subunit
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
SANT and BTB domain regulator of class switch recombination
GDH/6PGL endoplasmic bifunctional protein
Conserved oligomeric Golgi complex subunit 2 N-terminal
Immediate early response 3-interacting protein 1
Interleukin-13 receptor subunit alpha-1 Ig-like
tRNA-splicing endonuclease subunit Sen54 N-terminal
3-hydroxy-3-methylglutaryl-coenzyme A reductase
NPC intracellular cholesterol transporter 2
Mesencephalic astrocyte-derived neurotrophic factor
Serine/threonine/tyrosine-interacting protein B
39S ribosomal protein L14, mitochondrial
Coiled-coil and C2 domain-containing protein 1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1
Acetyl-CoA acetyltransferase A, mitochondrial
Increases nucleophilicity of active site Cys
Peroxisome proliferator-activated receptor delta
Coenzyme Q-binding protein COQ10 homolog A, mitochondrial
Small ribosomal subunit protein mS23 conserved
Tyrosine aminotransferase ubiquitination region
Transforming acidic coiled-coil-containing protein C-terminal
Cysteine and histidine-rich domain-containing protein 1
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal
O-linked (Xyl...) (glycosaminoglycan) serine
Sister chromatid cohesion protein PDS5 homolog B-B
Replication protein A 70 kDa DNA-binding subunit
C-type lectin domain family 3 member A homolog
A disintegrin and metalloproteinase with thrombospondin motifs 16
Disintegrin and metalloproteinase domain-containing protein 11
TRF2-interacting telomeric protein/Rap1 C-terminal
Telomeric repeat-binding factor 2-interacting protein 1
Guanylate-binding protein/Atlastin C-terminal
Eukaryotic translation initiation factor 3 subunit H
Leucine-rich repeat-containing G-protein coupled receptor 5A
Interaction with coactivator LXXLL motif
WD repeat-containing protein 18 C-terminal
Ricin B lectin domain-containing protein
Kazal-type serine protease inhibitor domain-containing protein 1
Histone-arginine methyltransferase METTL23
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Gly-Pro-Asn (GPN)-loop; involved in dimer interface
Stabilizes the phosphate intermediate; shared with dimeric partner
Phosphorylated adapter RNA export protein RNA-binding
Activator of Hsp90 ATPase AHSA1-like N-terminal
Ubiquitin carboxyl-terminal hydrolase 44-B
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Thiazolidine linkage to a ring-opened DNA abasic site
Nucleolus and neural progenitor protein-like N-terminal
CCR4-NOT transcription complex subunit 7
Transcriptional activator protein Pur-beta-B
Actin-related protein 2/3 complex subunit
Actin-related protein 2/3 complex subunit 1B-A
Protein phosphatase 1 regulatory subunit 21 C-terminal
Protein phosphatase 1 regulatory subunit 21 N-terminal
Extracellular Endonuclease subunit A domain-containing protein
Sodium-coupled monocarboxylate transporter 1
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
POU domain, class 3, transcription factor 4-B
Malonate--CoA ligase ACSF3, mitochondrial
SPRY domain-containing SOCS box protein 3
Spindle assembly abnormal protein 6 N-terminal
Small ribosomal subunit protein mS35 mitochondrial conserved
Mitochondrial import inner membrane translocase subunit Tim10-B
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Abolishes serine/threonine-protein kinase activity and ability to regulate mitosis.
Abolishes the ability to regulate M phase.
Serine/threonine-protein kinase greatwall
Ubiquitin-like modifier-activating enzyme Atg7 N-terminal
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein
TATA element modulatory factor 1 TATA binding
Large ribosomal subunit protein uL30 N-terminal eukaryotes
Vacuolar protein-sorting-associated protein 25
Gastrin/cholecystokinin peptide hormone domain-containing protein
Abolishes degradation by the proteasome due to the disrupted interaction with pcna.
Abolishes degradation by the proteasome without affecting the interaction with pcna.
Ubiquitin carboxyl-terminal hydrolase 10-B
Actin-related protein 2/3 complex subunit 1A-B
FAD-dependent oxidoreductase domain-containing protein 1