83332:Rv2703
gene id: 83332:Rv2703
uniprot id: P9WGI1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acidic residues
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: Interaction with polymerase core subunit RpoC
up seq anno comments: Loss of interaction with WhiB3.
up seq anno comments: Polar residues
up seq anno comments: RNA polymerase sigma factor SigA
up seq anno comments: Sigma-70 factor domain-1
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-3
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000093901

83332:Rv3054c
gene id: 83332:Rv3054c
uniprot id: P95105
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NADPH-dependent FMN reductase-like

83332:Rv1184c
gene id: 83332:Rv1184c
uniprot id: O50440
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Diacyltrehalose acyltransferase Chp2
up seq anno comments: Helical
up seq anno comments: Lack of activity.
up seq anno comments: PE-PPE
up seq anno feature ids: PRO_0000432824

83332:Rv2037c
gene id: 83332:Rv2037c
uniprot id: L0TB61
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: DGA/G
up seq anno comments: GXGXXG
up seq anno comments: GXSXG
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor

83332:Rv2878c
gene id: 83332:Rv2878c
uniprot id: P9WG65
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno comments: Redox-active
up seq anno comments: Soluble secreted antigen MPT53
up seq anno feature ids: PRO_0000034290

83332:Rv2529
gene id: 83332:Rv2529
uniprot id: P95024
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: ERCC4
up seq anno comments: Polar residues

83332:Rv2001
gene id: 83332:Rv2001
uniprot id: P9WLN5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2001
up seq anno feature ids: PRO_0000103929

83332:Rv0159c
gene id: 83332:Rv0159c
uniprot id: Q79G04
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE family protein PE3
up seq anno comments: PE-PPE
up seq anno feature ids: PRO_0000438129

83332:Rv1433
gene id: 83332:Rv1433
uniprot id: O06825
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Binds to carbapenem drug (covalent)
up seq anno comments: L,D-TPase catalytic
up seq anno comments: Nucleophile
up seq anno comments: Probable L,D-transpeptidase 3
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000430335

83332:Rv0066c
gene id: 83332:Rv0066c
uniprot id: O53611
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Site
up seq anno comments: Critical for catalysis

83332:Rv1441c
gene id: 83332:Rv1441c
uniprot id: Q79FP3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS26
up seq anno feature ids: PRO_5004286886

83332:Rv3179
gene id: 83332:Rv3179
uniprot id: O53329
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA
up seq anno comments: DUF4143

83332:Rv2100
gene id: 83332:Rv2100
uniprot id: P9WLJ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2100
up seq anno feature ids: PRO_0000014124

83332:Rv1576c
gene id: 83332:Rv1576c
uniprot id: O06614
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1078
gene id: 83332:Rv1078
uniprot id: P9WIM7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Proline-rich antigen homolog
up seq anno comments: RDD
up seq anno feature ids: PRO_0000058567

83332:Rv3327
gene id: 83332:Rv3327
uniprot id: O53377
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS110-like N-terminal
up seq anno comments: Transposase IS116/IS110/IS902 C-terminal

83332:Rv0206c
gene id: 83332:Rv0206c
uniprot id: P9WJV5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Confers resistance to BM212.
up seq anno comments: Confers resistance to C215.
up seq anno comments: Confers resistance to SQ109.
up seq anno comments: Confers resistance to indoleamides.
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Increases resistance to AU1235.
up seq anno comments: Part of the proton transportation network
up seq anno comments: Part of the proton-transportation channel
up seq anno comments: Periplasmic
up seq anno comments: Polar residues
up seq anno comments: Trehalose monomycolate exporter MmpL3
up seq anno feature ids: PRO_0000103564

83332:Rv1404
gene id: 83332:Rv1404
uniprot id: P71672
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH marR-type

83332:Rv0033
gene id: 83332:Rv0033
uniprot id: I6WX95
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier

83332:Rv2682c
gene id: 83332:Rv2682c
uniprot id: P9WNS3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 1-deoxy-D-xylulose-5-phosphate synthase
up seq anno feature ids: PRO_0000189130

83332:Rv3602c
gene id: 83332:Rv3602c
uniprot id: P9WIL5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: 50-fold reduction in activity and slight reduction in the affinity for beta-alanine. 30- and 40-fold decrease in adenylate formation and pantothenate formation, respectively.
up seq anno comments: More than 1000-fold reduction in activity and 120-fold decrease in adenylate formation. The enzymatic activity and the affinity for beta-alanine can be increased 10- and 3-fold, respectively, by alkylation of cysteine of mutant C-160.
up seq anno comments: More than 1000-fold reduction in activity and 45-fold decrease in adenylate formation.
up seq anno comments: More than 1000-fold reduction in activity and 50-fold decrease in adenylate formation.
up seq anno comments: More than 1000-fold reduction in activity and 50-fold decrease in the affinity for ATP.
up seq anno comments: More than 1000-fold reduction in activity and 52-fold decrease in adenylate formation.
up seq anno comments: More than 1000-fold reduction in activity and 60-fold decrease in adenylate formation. 10-fold decrease in the affinity for ATP.
up seq anno comments: N-acetylthreonine
up seq anno comments: No effect.
up seq anno comments: Pantothenate synthetase
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000128245

83332:Rv2220
gene id: 83332:Rv2220
uniprot id: P9WN39
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: GS beta-grasp
up seq anno comments: GS catalytic
up seq anno comments: Glutamine synthetase
up seq anno comments: O-AMP-tyrosine
up seq anno comments: Removed
up seq anno comments: Unable to be adenylylated.
up seq anno feature ids: PRO_0000153246

83332:Rv0924c
gene id: 83332:Rv0924c
uniprot id: P9WIZ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Divalent metal cation transporter MntH
up seq anno comments: Helical
up seq anno feature ids: PRO_0000212627

83332:Rv1689
gene id: 83332:Rv1689
uniprot id: P9WFT1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: S4 RNA-binding
up seq anno comments: Tyrosine--tRNA ligase
up seq anno feature ids: PRO_0000055660

83332:Rv1880c
gene id: 83332:Rv1880c
uniprot id: P9WPL9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 140
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052302

83332:Rv2047c
gene id: 83332:Rv2047c
uniprot id: P9WIH5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2047c
up seq anno feature ids: PRO_0000147101

83332:Rv1521
gene id: 83332:Rv1521
uniprot id: P9WQ45
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Putative fatty-acid--CoA ligase fadD25
up seq anno feature ids: PRO_0000193137

83332:Rv2369c
gene id: 83332:Rv2369c
uniprot id: L0TC46
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2192c
gene id: 83332:Rv2192c
uniprot id: P9WFX5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Anthranilate phosphoribosyltransferase
up seq anno comments: Disordered
up seq anno comments: N-acetylalanine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000154461

83332:Rv0258c
gene id: 83332:Rv0258c
uniprot id: P95215
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Tetracyclin repressor-like C-terminal

83332:Rv3012c
gene id: 83332:Rv3012c
uniprot id: P9WN59
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Glutamyl-tRNA(Gln) amidotransferase subunit C
up seq anno feature ids: PRO_0000105312

83332:Rv3897c
gene id: 83332:Rv3897c
uniprot id: O07036
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv3860
gene id: 83332:Rv3860
uniprot id: P96217
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: CobQ/CobB/MinD/ParA nucleotide binding
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv1106c
gene id: 83332:Rv1106c
uniprot id: P9WQP7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000403957

83332:Rv2845c
gene id: 83332:Rv2845c
uniprot id: P9WFT9
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Proline--tRNA ligase
up seq anno feature ids: PRO_0000139336

83332:Rv0061c
gene id: 83332:Rv0061c
uniprot id: I6X8E6
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Secreted protein
up seq anno feature ids: PRO_5003706633

83332:Rv3206c
gene id: 83332:Rv3206c
uniprot id: P9WMN7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Cysteine persulfide intermediate; for sulfurtransferase activity
up seq anno comments: Glycyl thioester intermediate; for adenylyltransferase activity
up seq anno comments: Helical
up seq anno comments: Probable adenylyltransferase/sulfurtransferase MoeZ
up seq anno comments: Rhodanese
up seq anno feature ids: PRO_0000401136

83332:Rv0557
gene id: 83332:Rv0557
uniprot id: P9WMY5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: GDP-mannose-dependent alpha-mannosyltransferase
up seq anno feature ids: PRO_0000393729

83332:Rv3693
gene id: 83332:Rv3693
uniprot id: O69661
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF58

83332:Rv0919
gene id: 83332:Rv0919
uniprot id: I6XA42
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: N-acetyltransferase

83332:Rv2307c
gene id: 83332:Rv2307c
uniprot id: P9WLC7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2307c
up seq anno feature ids: PRO_0000104016

83332:Rv3864
gene id: 83332:Rv3864
uniprot id: P9WJD3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion-associated protein EspE
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000393950

83332:Rv0384c
gene id: 83332:Rv0384c
uniprot id: P9WPD1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: C-terminal
up seq anno comments: Chaperone protein ClpB
up seq anno comments: Clp R
up seq anno comments: Linker
up seq anno comments: NBD1
up seq anno comments: NBD2
up seq anno comments: Repeat 1
up seq anno comments: Repeat 2
up seq anno feature ids: PRO_0000191146

83332:Rv1226c
gene id: 83332:Rv1226c
uniprot id: O33222
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF304
up seq anno comments: Helical

83332:Rv3248c
gene id: 83332:Rv3248c
uniprot id: P9WGV3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adenosylhomocysteinase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno feature ids: PRO_0000116971

83332:Rv1892
gene id: 83332:Rv1892
uniprot id: O07740
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2713
gene id: 83332:Rv2713
uniprot id: P9WHH5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable soluble pyridine nucleotide transhydrogenase
up seq anno feature ids: PRO_0000068065

83332:Rv3064c
gene id: 83332:Rv3064c
uniprot id: I6XG31
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1194c
gene id: 83332:Rv1194c
uniprot id: O05296
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CdaR GGDEF-like
up seq anno comments: PucR C-terminal helix-turn-helix

83332:Rv2890c
gene id: 83332:Rv2890c
uniprot id: P9WH39
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Small ribosomal subunit protein uS2
up seq anno feature ids: PRO_0000134203

83332:Rv2540c
gene id: 83332:Rv2540c
uniprot id: P9WPY1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Chorismate synthase
up seq anno feature ids: PRO_0000140615

83332:Rv0257
gene id: 83332:Rv0257
uniprot id: L7N694
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv0076c
gene id: 83332:Rv0076c
uniprot id: O53621
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1507A
gene id: 83332:Rv1507A
uniprot id: L7N6B6
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3193c
gene id: 83332:Rv3193c
uniprot id: P9WFL3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: UPF0182 protein Rv3193c
up seq anno feature ids: PRO_0000157724

83332:Rv0217c
gene id: 83332:Rv0217c
uniprot id: P96399
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alpha/beta hydrolase fold-3

83332:Rv3877
gene id: 83332:Rv3877
uniprot id: P9WNQ7
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: ESX-1 secretion system protein EccD1
up seq anno comments: Helical
up seq anno comments: N-acetylserine
up seq anno comments: Periplasmic
up seq anno comments: Removed
up seq anno feature ids: PRO_0000393233

83332:Rv3339c
gene id: 83332:Rv3339c
uniprot id: P9WKL1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Critical for catalysis
up seq anno comments: Isocitrate dehydrogenase [NADP]
up seq anno comments: Phosphoserine
up seq anno feature ids: PRO_0000083555

83332:Rv0729
gene id: 83332:Rv0729
uniprot id: I6Y4K0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carbohydrate kinase FGGY C-terminal
up seq anno comments: Carbohydrate kinase FGGY N-terminal

83332:Rv0044c
gene id: 83332:Rv0044c
uniprot id: P71701
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv2772c
gene id: 83332:Rv2772c
uniprot id: I6YA75
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0562
gene id: 83332:Rv0562
uniprot id: O06428
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno comments: DDXXD motif
up seq anno comments: Important for determining product chain length
up seq anno comments: Leads to the appearance of shorter chain products, GPP and E,E-FPP, with only small amounts of GGPP produced.
up seq anno comments: Nonaprenyl diphosphate synthase
up seq anno feature ids: PRO_0000451297

83332:Rv0880
gene id: 83332:Rv0880
uniprot id: P9WMF1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH marR-type
up seq anno comments: HTH-type transcriptional regulator Rv0880
up seq anno feature ids: PRO_0000054407

83332:Rv1734c
gene id: 83332:Rv1734c
uniprot id: P9WLS7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1734c
up seq anno feature ids: PRO_0000392907

83332:Rv0526
gene id: 83332:Rv0526
uniprot id: O06392
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_5038653001

83332:Rv2230c
gene id: 83332:Rv2230c
uniprot id: P9WFM1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: GTP cyclohydrolase 1 type 2 homolog
up seq anno feature ids: PRO_0000147318

83332:Rv0994
gene id: 83332:Rv0994
uniprot id: P9WJQ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Molybdopterin molybdenumtransferase 1
up seq anno feature ids: PRO_0000170991

83332:Rv1699
gene id: 83332:Rv1699
uniprot id: P9WHK7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 14-fold reduction in catalytic activity. 10-fold decrease in affinity for ATP but no change in affinity for UTP. Causes resistance to the anti-tubercular compounds 7947882 and 7904688. Catalytic activity cannot be inhibited by the active metabolite of 7947882.
up seq anno comments: Amidoligase domain
up seq anno comments: CTP synthase
up seq anno comments: Disordered
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: Nucleophile; for glutamine hydrolysis
up seq anno feature ids: PRO_0000138202

83332:Rv0700
gene id: 83332:Rv0700
uniprot id: P9WH67
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein uS10
up seq anno feature ids: PRO_0000146560

83332:Rv2058c
gene id: 83332:Rv2058c
uniprot id: P9WHA9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL28B
up seq anno feature ids: PRO_0000178513

83332:Rv1207
gene id: 83332:Rv1207
uniprot id: P9WNC9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Characteristic for family members without dihydropteroate synthase activity
up seq anno comments: Disordered
up seq anno comments: Inactive dihydropteroate synthase 2
up seq anno comments: Pterin-binding
up seq anno feature ids: PRO_0000168216

83332:Rv1531
gene id: 83332:Rv1531
uniprot id: O53905
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxymuconolactone decarboxylase-like

83332:Rv0167
gene id: 83332:Rv0167
uniprot id: O07412
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2380c
gene id: 83332:Rv2380c
uniprot id: I6Y0L1
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Carrier
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv2202c
gene id: 83332:Rv2202c
uniprot id: P9WID5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adenosine kinase
up seq anno comments: N-acetylthreonine
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000080064

83332:Rv2717c
gene id: 83332:Rv2717c
uniprot id: P9WFG7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: GXWXGXG
up seq anno comments: Peroxynitrite isomerase 1
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000356934

83332:Rv3026c
gene id: 83332:Rv3026c
uniprot id: I6XFY8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv3908
gene id: 83332:Rv3908
uniprot id: P9WIX7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Nudix box
up seq anno comments: Nudix hydrolase
up seq anno comments: Putative mutator protein MutT4
up seq anno feature ids: PRO_0000392934

83332:Rv2681
gene id: 83332:Rv2681
uniprot id: I6XF17
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HRDC

83332:Rv1117
gene id: 83332:Rv1117
uniprot id: O06569
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABM

83332:Rv2858c
gene id: 83332:Rv2858c
uniprot id: O33340
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Aldehyde dehydrogenase

83332:Rv0568
gene id: 83332:Rv0568
uniprot id: P9WPM9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative cytochrome P450 135B1
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052293

83332:Rv3703c
gene id: 83332:Rv3703c
uniprot id: O69671
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Hercynine oxygenase
up seq anno feature ids: PRO_0000413648

83332:Rv0931c
gene id: 83332:Rv0931c
uniprot id: P9WI79
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 2600-fold decrease in activity.
up seq anno comments: Cytoplasmic
up seq anno comments: Decreases activity and alters substrate specificity.
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Lack of activity.
up seq anno comments: N-acetylserine
up seq anno comments: NHL 1
up seq anno comments: NHL 2
up seq anno comments: NHL 3
up seq anno comments: NHL 4
up seq anno comments: NHL 5
up seq anno comments: NHL 6
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno comments: Serine/threonine-protein kinase PknD
up seq anno feature ids: PRO_0000171209

83332:Rv2319c
gene id: 83332:Rv2319c
uniprot id: P9WLB5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Universal stress protein Rv2319c
up seq anno feature ids: PRO_0000104026

83332:Rv1563c
gene id: 83332:Rv1563c
uniprot id: P9WQ21
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative maltooligosyl trehalose synthase
up seq anno feature ids: PRO_0000054342

83332:Rv1196
gene id: 83332:Rv1196
uniprot id: L7N675
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: PPE family protein PPE18
up seq anno feature ids: PRO_0000438002

83332:Rv1236
gene id: 83332:Rv1236
uniprot id: P9WG03
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Trehalose transport system permease protein SugA
up seq anno feature ids: PRO_0000419315

83332:Rv2971
gene id: 83332:Rv2971
uniprot id: P9WQA5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Aldo-keto reductase Rv2971
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000380747

83332:Rv1057
gene id: 83332:Rv1057
uniprot id: O53405
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Seven-bladed beta-propeller protein Rv1057
up seq anno feature ids: PRO_0000451064

83332:Rv1902c
gene id: 83332:Rv1902c
uniprot id: O07730
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile

83332:Rv3075c
gene id: 83332:Rv3075c
uniprot id: I6YF40
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: HpcH/HpaI aldolase/citrate lyase

83332:Rv2555c
gene id: 83332:Rv2555c
uniprot id: P9WFW7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Alanine--tRNA ligase
up seq anno feature ids: PRO_0000075147

83332:Rv3387
gene id: 83332:Rv3387
uniprot id: O50414
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS4-like

83332:Rv2019
gene id: 83332:Rv2019
uniprot id: O53465
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative ribonuclease VapC45
up seq anno feature ids: PRO_0000433056

83332:Rv0627
gene id: 83332:Rv0627
uniprot id: P96917
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC5
up seq anno feature ids: PRO_0000407868

83332:Rv2384
gene id: 83332:Rv2384
uniprot id: P71716
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Salicyl-AMP ligase / salicyl-S-ArCP synthetase
up seq anno feature ids: PRO_0000445644

83332:Rv3573c
gene id: 83332:Rv3573c
uniprot id: P96855
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Acyl-CoA dehydrogenase FadE34
up seq anno comments: Displays less than 1% activity with cholyl-CoA as substrate. Still binds FAD.
up seq anno comments: Displays less than 2% activity with cholyl-CoA as substrate. Cannot bind FAD.
up seq anno feature ids: PRO_0000438519

83332:Rv0086
gene id: 83332:Rv0086
uniprot id: Q10883
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

83332:Rv1646
gene id: 83332:Rv1646
uniprot id: L7N681
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3203
gene id: 83332:Rv3203
uniprot id: L0TC47
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Charge relay system
up seq anno comments: Lipase LipV
up seq anno comments: Loss of enzymatic activity.
up seq anno comments: Loss of more than 70% enzymatic activity.
up seq anno comments: No effect on enzymatic activity.
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000432515

83332:Rv1851
gene id: 83332:Rv1851
uniprot id: P9WFE5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Urease accessory protein UreF
up seq anno feature ids: PRO_0000067651

83332:Rv0944
gene id: 83332:Rv0944
uniprot id: L0T864
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Zinc Finger
up seq anno labels: Chain
up seq anno labels: Zinc Finger
up seq anno comments: FPG-type
up seq anno comments: Uncharacterized formamidopyrimidine-DNA glycosylase-like protein
up seq anno feature ids: PRO_0000421384

83332:Rv3392c
gene id: 83332:Rv3392c
uniprot id: P9WPB7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cyclopropane mycolic acid synthase 1
up seq anno feature ids: PRO_0000089566

83332:Rv3354
gene id: 83332:Rv3354
uniprot id: O50383
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: DUF732
up seq anno comments: DUF732 domain-containing protein
up seq anno feature ids: PRO_5039637566

83332:Rv3887c
gene id: 83332:Rv3887c
uniprot id: P9WNQ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-2 secretion system protein eccD2
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393234

83332:Rv0740
gene id: 83332:Rv0740
uniprot id: O53803
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein Rv0740
up seq anno feature ids: PRO_0000432517

83332:Rv2782c
gene id: 83332:Rv2782c
uniprot id: P9WHT5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized zinc protease Rv2782c
up seq anno feature ids: PRO_0000074423

83332:Rv0572c
gene id: 83332:Rv0572c
uniprot id: P9WM81
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0572c
up seq anno feature ids: PRO_0000392683

83332:Rv1419
gene id: 83332:Rv1419
uniprot id: P9WLX9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Ricin B-type lectin
up seq anno comments: Uncharacterized protein Rv1419
up seq anno feature ids: PRO_0000103845

83332:Rv0890c
gene id: 83332:Rv0890c
uniprot id: P9WMG1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH luxR-type
up seq anno comments: Putative HTH-type transcriptional regulator Rv0890c
up seq anno feature ids: PRO_0000184201

83332:Rv0539
gene id: 83332:Rv0539
uniprot id: P9WMY1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized glycosyltransferase Rv0539
up seq anno feature ids: PRO_0000059248

83332:Rv2241
gene id: 83332:Rv2241
uniprot id: P9WIS9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Crosslink
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Polar residues
up seq anno comments: Pyruvate dehydrogenase E1 component
up seq anno feature ids: PRO_0000162246

83332:Rv1091
gene id: 83332:Rv1091
uniprot id: Q79FS5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv1251c
gene id: 83332:Rv1251c
uniprot id: O50466
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DNA2/NAM7 helicase-like C-terminal
up seq anno comments: YprB ribonuclease H-like

83332:Rv0710
gene id: 83332:Rv0710
uniprot id: P9WH51
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Small ribosomal subunit protein uS17
up seq anno feature ids: PRO_0000128471

83332:Rv2427c
gene id: 83332:Rv2427c
uniprot id: P9WHV1
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Gamma-glutamyl phosphate reductase
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000189753

83332:Rv1218c
gene id: 83332:Rv1218c
uniprot id: O86311
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Multidrug efflux system ATP-binding protein Rv1218c
up seq anno feature ids: PRO_0000447330

83332:Rv2069
gene id: 83332:Rv2069
uniprot id: P9WGH1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Turn
up seq anno comments: Blue shift in fluorescence emission, possible decrease in -10 promoter recognition.
up seq anno comments: ECF RNA polymerase sigma factor SigC
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: Red shift in fluorescence emission.
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000094021

83332:Rv2392
gene id: 83332:Rv2392
uniprot id: P9WIK3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adenosine 5'-phosphosulfate reductase
up seq anno comments: Nucleophile; cysteine thiosulfonate intermediate
up seq anno feature ids: PRO_0000100633

83332:Rv2901c
gene id: 83332:Rv2901c
uniprot id: P9WL27
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv2901c
up seq anno feature ids: PRO_0000104096

83332:Rv2727c
gene id: 83332:Rv2727c
uniprot id: P9WJW1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Interaction with substrate tRNA
up seq anno comments: tRNA dimethylallyltransferase
up seq anno feature ids: PRO_0000163942

83332:Rv3036c
gene id: 83332:Rv3036c
uniprot id: I6YF08
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Esterase Rv3036c
up seq anno comments: Helical
up seq anno feature ids: PRO_5010212191

83332:Rv3585
gene id: 83332:Rv3585
uniprot id: P9WHJ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Zinc Finger
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Zinc Finger
up seq anno comments: C4-type
up seq anno comments: DNA repair protein RadA
up seq anno comments: Disordered
up seq anno comments: Lon-protease-like
up seq anno comments: RadA KNRFG motif
up seq anno feature ids: PRO_0000187932

83332:Rv3919c
gene id: 83332:Rv3919c
uniprot id: P9WGW9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Ribosomal RNA small subunit methyltransferase G
up seq anno feature ids: PRO_0000184283

83332:Rv2869c
gene id: 83332:Rv2869c
uniprot id: P9WHS3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Loss of PbpB (PBP3, FtsI) processing.
up seq anno comments: No effect on PbpB (PBP3, FtsI) processing.
up seq anno comments: PDZ
up seq anno comments: Zinc metalloprotease Rip1
up seq anno feature ids: PRO_0000088449

83332:Rv3403c
gene id: 83332:Rv3403c
uniprot id: P9WKZ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv3403c
up seq anno feature ids: PRO_0000104123

83332:Rv3364c
gene id: 83332:Rv3364c
uniprot id: O50393
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Serine protease inhibitor Rv3364c
up seq anno feature ids: PRO_0000438185

83332:Rv0263c
gene id: 83332:Rv0263c
uniprot id: P95220
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxyltransferase

83332:Rv3398c
gene id: 83332:Rv3398c
uniprot id: P9WKH1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: (2E,6E)-farnesyl diphosphate synthase
up seq anno comments: DDXXD motif
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000123968

83332:Rv2332
gene id: 83332:Rv2332
uniprot id: P9WK25
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Putative malate oxidoreductase [NAD]
up seq anno feature ids: PRO_0000160248

83332:Rv0227c
gene id: 83332:Rv0227c
uniprot id: P96409
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv1706c
gene id: 83332:Rv1706c
uniprot id: P9WI17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE23
up seq anno feature ids: PRO_0000378479

83332:Rv0411c
gene id: 83332:Rv0411c
uniprot id: P96257
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: Solute-binding protein family 3/N-terminal
up seq anno feature ids: PRO_5039266489

83332:Rv0056
gene id: 83332:Rv0056
uniprot id: P9WH79
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL9
up seq anno feature ids: PRO_0000176655

83332:Rv1758
gene id: 83332:Rv1758
uniprot id: O06793
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Site
up seq anno comments: Nucleophile
up seq anno comments: Probable carboxylesterase Culp5
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000450108

83332:Rv1247c
gene id: 83332:Rv1247c
uniprot id: O50462
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin RelB
up seq anno feature ids: PRO_0000406201

83332:Rv2981c
gene id: 83332:Rv2981c
uniprot id: P9WP31
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-grasp
up seq anno comments: D-alanine--D-alanine ligase
up seq anno feature ids: PRO_0000177844

83332:Rv0231
gene id: 83332:Rv0231
uniprot id: P96414
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal

83332:Rv0721
gene id: 83332:Rv0721
uniprot id: P9WH33
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: N-acetylalanine
up seq anno comments: Removed
up seq anno comments: S5 DRBM
up seq anno comments: Small ribosomal subunit protein uS5
up seq anno feature ids: PRO_0000131556

83332:Rv1069c
gene id: 83332:Rv1069c
uniprot id: O53417
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Alpha/beta-hydrolase N-terminal
up seq anno comments: Alpha/beta-hydrolase catalytic
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv1912c
gene id: 83332:Rv1912c
uniprot id: O07721
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Enoyl reductase (ER)

83332:Rv3679
gene id: 83332:Rv3679
uniprot id: P9WKX5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Putative ATPase Rv3679
up seq anno feature ids: PRO_0000104143

83332:Rv3018c
gene id: 83332:Rv3018c
uniprot id: P9WHY9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE46
up seq anno feature ids: PRO_0000217851

83332:Rv1726
gene id: 83332:Rv1726
uniprot id: P71984
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv2567
gene id: 83332:Rv2567
uniprot id: P9WL97
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2567
up seq anno feature ids: PRO_0000104044

83332:Rv2212
gene id: 83332:Rv2212
uniprot id: P9WMU7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Guanylate cyclase
up seq anno comments: Uncharacterized protein Rv2212
up seq anno feature ids: PRO_0000074132

83332:Rv3399
gene id: 83332:Rv3399
uniprot id: P9WFH1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv3399
up seq anno feature ids: PRO_0000104118

83332:Rv0637
gene id: 83332:Rv0637
uniprot id: P9WFJ9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: UPF0336 protein Rv0637
up seq anno feature ids: PRO_0000216144

83332:Rv2030c
gene id: 83332:Rv2030c
uniprot id: P9WLM1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2030c
up seq anno feature ids: PRO_0000392909

83332:Rv2398c
gene id: 83332:Rv2398c
uniprot id: P71746
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv0097
gene id: 83332:Rv0097
uniprot id: P9WG83
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: (3R)-3-[(carboxymethyl)amino]fatty acid oxygenase/decarboxylase
up seq anno feature ids: PRO_0000194020

83332:Rv3215
gene id: 83332:Rv3215
uniprot id: P9WFW9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Putative isochorismate synthase MenF
up seq anno feature ids: PRO_0000399472

83332:Rv1862
gene id: 83332:Rv1862
uniprot id: P9WQC1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylvaline
up seq anno comments: Probable alcohol dehydrogenase AdhA
up seq anno comments: Removed
up seq anno feature ids: PRO_0000391341

83332:Rv2688c
gene id: 83332:Rv2688c
uniprot id: P9WQL7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Fluoroquinolones export ATP-binding protein Rv2688c
up seq anno feature ids: PRO_0000390878

83332:Rv3899c
gene id: 83332:Rv3899c
uniprot id: O05446
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DUF5631
up seq anno comments: DUF5632
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv0756c
gene id: 83332:Rv0756c
uniprot id: P71813
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3708c
gene id: 83332:Rv3708c
uniprot id: P9WNX5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Aspartate-semialdehyde dehydrogenase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000141383

83332:Rv2792c
gene id: 83332:Rv2792c
uniprot id: I6YA93
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: O-(5'-phospho-DNA)-serine intermediate
up seq anno comments: Resolvase/invertase-type recombinase catalytic

83332:Rv0583c
gene id: 83332:Rv0583c
uniprot id: O53780
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Lipoprotein LpqN
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_5010295865

83332:Rv1429
gene id: 83332:Rv1429
uniprot id: O06829
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CdaR GGDEF-like
up seq anno comments: PucR C-terminal helix-turn-helix

83332:Rv0900
gene id: 83332:Rv0900
uniprot id: P9WJG7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein ArfB
up seq anno feature ids: PRO_0000014083

83332:Rv1080c
gene id: 83332:Rv1080c
uniprot id: P9WMT9
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Transcription elongation factor GreA
up seq anno feature ids: PRO_0000176943

83332:Rv1261c
gene id: 83332:Rv1261c
uniprot id: P9WP13
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: F420H(2)-dependent quinone reductase Rv1261c
up seq anno feature ids: PRO_0000103778

83332:Rv2079
gene id: 83332:Rv2079
uniprot id: P9WLK7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2079
up seq anno feature ids: PRO_0000103951

83332:Rv2084
gene id: 83332:Rv2084
uniprot id: P9WLK1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2084
up seq anno feature ids: PRO_0000103955

83332:Rv2912c
gene id: 83332:Rv2912c
uniprot id: P9WMC7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv2912c
up seq anno feature ids: PRO_0000070668

83332:Rv1546
gene id: 83332:Rv1546
uniprot id: P9WLU7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1546
up seq anno feature ids: PRO_0000103876

83332:Rv3081
gene id: 83332:Rv3081
uniprot id: O53298
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2737c
gene id: 83332:Rv2737c
uniprot id: P9WHJ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: DOD-type homing endonuclease
up seq anno comments: Endonuclease PI-MtuI
up seq anno comments: In strain: Canetti and SO93.
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Protein RecA, 1st part
up seq anno comments: Protein RecA, 2nd part
up seq anno feature ids: PRO_0000030269
up seq anno feature ids: PRO_0000030270
up seq anno feature ids: PRO_0000030271

83332:Rv1375
gene id: 83332:Rv1375
uniprot id: P9WF27
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Uncharacterized protein Rv1375
up seq anno comments: YcaO
up seq anno feature ids: PRO_0000144978

83332:Rv3598c
gene id: 83332:Rv3598c
uniprot id: P9WFU9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Lysine--tRNA ligase 1
up seq anno feature ids: PRO_0000152655

83332:Rv0849
gene id: 83332:Rv0849
uniprot id: P9WJX5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter Rv0849
up seq anno feature ids: PRO_0000390682

83332:Rv2882c
gene id: 83332:Rv2882c
uniprot id: P9WGY1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Disordered
up seq anno comments: Ribosome-recycling factor
up seq anno feature ids: PRO_0000167500

83332:Rv3413c
gene id: 83332:Rv3413c
uniprot id: P9WJ71
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: 10-fold reduction in binding to SigD.
up seq anno comments: Anti-sigma-D factor RsdA
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Interaction with sigma factor
up seq anno comments: No proteolysis by ClpP1-ClpP2-ClpX.
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000104133

83332:Rv1518
gene id: 83332:Rv1518
uniprot id: P9WLV9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1518
up seq anno feature ids: PRO_0000103865

83332:Rv0274
gene id: 83332:Rv0274
uniprot id: O53680
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: VOC

83332:Rv3511
gene id: 83332:Rv3511
uniprot id: Q6MWW8
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv1793
gene id: 83332:Rv1793
uniprot id: P9WNJ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxN
up seq anno feature ids: PRO_0000167808

83332:Rv0951
gene id: 83332:Rv0951
uniprot id: P9WGC5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ATP-grasp
up seq anno comments: Succinate--CoA ligase [ADP-forming] subunit beta
up seq anno feature ids: PRO_0000102840

83332:Rv0421c
gene id: 83332:Rv0421c
uniprot id: P96267
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: KANL3/Tex30 alpha/beta hydrolase-like

83332:Rv1772
gene id: 83332:Rv1772
uniprot id: O06805
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ANTAR
up seq anno comments: Disordered

83332:Rv0910
gene id: 83332:Rv0910
uniprot id: P9WJ05
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Toxin Rv0910
up seq anno feature ids: PRO_0000406885

83332:Rv2991
gene id: 83332:Rv2991
uniprot id: O53240
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: Cysteine sulfenic acid (-SOH)
up seq anno comments: Pyridoxamine 5'-phosphate oxidase putative

83332:Rv3543c
gene id: 83332:Rv3543c
uniprot id: P71858
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Acyl-CoA dehydrogenase FadE29
up seq anno comments: Proton acceptor
up seq anno comments: Unable to dehydrogenate pregnene-carboxyl-CoA ester.
up seq anno feature ids: PRO_0000438518

83332:Rv0242c
gene id: 83332:Rv0242c
uniprot id: I6Y778
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 12-fold decrease in catalytic efficiency with NADH as substrate. 26-fold decrease in catalytic efficiency; when associated with A-146.
up seq anno comments: 2.2-fold decrease in catalytic efficiency with NADH as substrate. 26-fold decrease in catalytic efficiency; when associated with A-445.
up seq anno comments: 3-oxoacyl-[acyl-carrier-protein] reductase [NADH]
up seq anno comments: Drastic reduction of ketoreductase activity.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000451898

83332:Rv0731c
gene id: 83332:Rv0731c
uniprot id: P9WFI5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0731c
up seq anno feature ids: PRO_0000361243

83332:Rv1924c
gene id: 83332:Rv1924c
uniprot id: P95289
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3690
gene id: 83332:Rv3690
uniprot id: O69658
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF4129
up seq anno comments: Helical

83332:Rv2439c
gene id: 83332:Rv2439c
uniprot id: P9WHU9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Glutamate 5-kinase
up seq anno comments: PUA
up seq anno feature ids: PRO_0000109696

83332:Rv3112
gene id: 83332:Rv3112
uniprot id: L7N6B4
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Molybdopterin synthase sulfur carrier subunit
up seq anno feature ids: PRO_0000438347

83332:Rv0544c
gene id: 83332:Rv0544c
uniprot id: O06410
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3091
gene id: 83332:Rv3091
uniprot id: I6YB49
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: DGA/G
up seq anno comments: Disordered
up seq anno comments: GXGXXG
up seq anno comments: GXSXG
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor

83332:Rv0369c
gene id: 83332:Rv0369c
uniprot id: O53704
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2577
gene id: 83332:Rv2577
uniprot id: P9WL81
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Tat-type signal
up seq anno comments: Uncharacterized protein Rv2577
up seq anno feature ids: PRO_0000104060

83332:Rv0860
gene id: 83332:Rv0860
uniprot id: O53872
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: 3-hydroxyacyl-CoA dehydrogenase C-terminal
up seq anno comments: 3-hydroxyacyl-CoA dehydrogenase NAD binding

83332:Rv0648
gene id: 83332:Rv0648
uniprot id: P96937
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Glycoside hydrolase family 38 central

83332:Rv2040c
gene id: 83332:Rv2040c
uniprot id: O53484
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv2409c
gene id: 83332:Rv2409c
uniprot id: P71734
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transglutaminase-like

83332:Rv2893
gene id: 83332:Rv2893
uniprot id: I6YEN3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv1872c
gene id: 83332:Rv1872c
uniprot id: P9WND5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: FMN hydroxy acid dehydrogenase
up seq anno comments: Proton acceptor
up seq anno comments: Putative L-lactate dehydrogenase
up seq anno feature ids: PRO_0000390893

83332:Rv2700
gene id: 83332:Rv2700
uniprot id: I6Y1I5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: LytR/CpsA/Psr regulator C-terminal

83332:Rv3910
gene id: 83332:Rv3910
uniprot id: P9WJK3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Abolishes phosphorylation by PknB.
up seq anno comments: Basic and acidic residues
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: N-acetylmethionine
up seq anno comments: Phosphothreonine
up seq anno comments: Polar residues
up seq anno comments: Probable peptidoglycan biosynthesis protein MviN
up seq anno feature ids: PRO_0000419663

83332:Rv0767c
gene id: 83332:Rv0767c
uniprot id: P9WMD7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0767c
up seq anno feature ids: PRO_0000070659

83332:Rv2526
gene id: 83332:Rv2526
uniprot id: P9WJ49
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB17
up seq anno feature ids: PRO_0000408063

83332:Rv3370c
gene id: 83332:Rv3370c
uniprot id: P9WNT5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Error-prone DNA polymerase
up seq anno feature ids: PRO_0000103385

83332:Rv3004
gene id: 83332:Rv3004
uniprot id: P9WIR1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: Low molecular weight protein antigen 6
up seq anno feature ids: PRO_0000089575

83332:Rv0595c
gene id: 83332:Rv0595c
uniprot id: O07783
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Does not inhibit growth, forms complex with VapB4.
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC4
up seq anno feature ids: PRO_0000407867

83332:Rv0129c
gene id: 83332:Rv0129c
uniprot id: P9WQN9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Diacylglycerol acyltransferase/mycolyltransferase Ag85C
up seq anno comments: Do not form alpha,alpha-trehalose dimycolate (TDM, cord factor) and alpha,alpha-trehalose monomycolate (TMM).
up seq anno comments: Fibronectin-binding
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000000226

83332:Rv0252
gene id: 83332:Rv0252
uniprot id: O53674
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: BFD-like [2Fe-2S]-binding
up seq anno comments: FAD/NAD(P)-binding
up seq anno comments: NADH-rubredoxin oxidoreductase C-terminal
up seq anno comments: Nitrite/Sulfite reductase ferredoxin-like
up seq anno comments: Nitrite/sulphite reductase 4Fe-4S

83332:Rv1440
gene id: 83332:Rv1440
uniprot id: P9WGN5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable protein-export membrane protein SecG
up seq anno feature ids: PRO_0000157235

83332:Rv3190c
gene id: 83332:Rv3190c
uniprot id: O53336
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1271c
gene id: 83332:Rv1271c
uniprot id: P9WM43
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1271c
up seq anno feature ids: PRO_0000014091

83332:Rv1395
gene id: 83332:Rv1395
uniprot id: P9WMJ1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH araC/xylS-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv1395
up seq anno feature ids: PRO_0000194624

83332:Rv2095c
gene id: 83332:Rv2095c
uniprot id: P9WIL9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein PafC
up seq anno feature ids: PRO_0000014122

83332:Rv1736c
gene id: 83332:Rv1736c
uniprot id: P9WJQ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 4Fe-4S Mo/W bis-MGD-type
up seq anno comments: Helical
up seq anno comments: Nitrate reductase alpha subunit
up seq anno comments: Nitrate reductase delta subunit
up seq anno comments: Nitrate reductase gamma subunit
up seq anno comments: Nitrate reductase-like protein NarX
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000392915

83332:Rv2922c
gene id: 83332:Rv2922c
uniprot id: P9WGF3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno comments: Chromosome partition protein Smc
up seq anno comments: SMC hinge
up seq anno feature ids: PRO_0000119030

83332:Rv1558
gene id: 83332:Rv1558
uniprot id: P9WP11
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: F420H(2)-dependent quinone reductase Rv1558
up seq anno comments: Removed
up seq anno feature ids: PRO_0000103879

83332:Rv1894c
gene id: 83332:Rv1894c
uniprot id: O07738
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nitronate monooxygenase

83332:Rv2749
gene id: 83332:Rv2749
uniprot id: O33291
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABM

83332:Rv1388
gene id: 83332:Rv1388
uniprot id: P71658
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Decreased ability to bind dsDNA, unwinds but does not collapse cosmid DNA.
up seq anno comments: H2TH motif, binds DNA
up seq anno comments: Integration host factor
up seq anno comments: Lid, binds DNA
up seq anno comments: Protein is unstable.
up seq anno feature ids: PRO_0000458543

83332:Rv3423c
gene id: 83332:Rv3423c
uniprot id: P9WQA9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alanine racemase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Proton acceptor; specific for D-alanine
up seq anno comments: Proton acceptor; specific for L-alanine
up seq anno feature ids: PRO_0000114539

83332:Rv0290
gene id: 83332:Rv0290
uniprot id: P9WNQ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-3 secretion system protein EccD3
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393235

83332:Rv3566c
gene id: 83332:Rv3566c
uniprot id: P9WJI5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Arylamine N-acetyltransferase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000107919

83332:Rv0777
gene id: 83332:Rv0777
uniprot id: I6XWA1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Adenylosuccinate lyase C-terminal

83332:Rv3729
gene id: 83332:Rv3729
uniprot id: O69696
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Radical SAM core

83332:Rv1844c
gene id: 83332:Rv1844c
uniprot id: Q79FJ2
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: 6-phosphogluconate dehydrogenase C-terminal
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: in other chain

83332:Rv0961
gene id: 83332:Rv0961
uniprot id: P9WKM9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0961
up seq anno feature ids: PRO_0000103757

83332:Rv0431
gene id: 83332:Rv0431
uniprot id: P96277
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: LytR/CpsA/Psr regulator C-terminal
up seq anno comments: Polar residues

83332:Rv0605
gene id: 83332:Rv0605
uniprot id: I6Y890
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: O-(5'-phospho-DNA)-serine intermediate
up seq anno comments: Resolvase/invertase-type recombinase catalytic

83332:Rv1782
gene id: 83332:Rv1782
uniprot id: P9WNQ9
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: ESX-5 secretion system ATPase EccB5
up seq anno comments: Helical
up seq anno comments: Periplasmic
up seq anno feature ids: PRO_0000393232

83332:Rv3553
gene id: 83332:Rv3553
uniprot id: P71847
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: (3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA dehydrogenase
up seq anno feature ids: PRO_0000452307

83332:Rv0744c
gene id: 83332:Rv0744c
uniprot id: O53807
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helix-turn-helix

83332:Rv3700c
gene id: 83332:Rv3700c
uniprot id: O69668
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable hercynylcysteine sulfoxide lyase
up seq anno feature ids: PRO_0000413654

83332:Rv2449c
gene id: 83332:Rv2449c
uniprot id: O53176
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Putative trans-acting enoyl reductase Rv2449c
up seq anno feature ids: PRO_0000396094

83332:Rv1583c
gene id: 83332:Rv1583c
uniprot id: P9WLU1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1583c
up seq anno feature ids: PRO_0000103885

83332:Rv0554
gene id: 83332:Rv0554
uniprot id: P9WNH1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Putative non-heme bromoperoxidase BpoC
up seq anno feature ids: PRO_0000414587

83332:Rv1085c
gene id: 83332:Rv1085c
uniprot id: P9WFN7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0073 membrane protein Rv1085c
up seq anno feature ids: PRO_0000176902

83332:Rv1411c
gene id: 83332:Rv1411c
uniprot id: P9WK45
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decreased TLR2 agonist activity, cannot acquire lipid from mycobacterial extracts, cavity entrance and size decrease. Binds PIM6, LM and ManLAM 10-100-fold less well than wild-type, binds de-acylated LM and ManLAM as well as wild-type. Decreased ability to transfer triacylglyceride between lipid bilayers.
up seq anno comments: Lipoarabinomannan carrier protein LprG
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Prevents bacterial uptake by a human macrophage-like cell line
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018146

83332:Rv2588c
gene id: 83332:Rv2588c
uniprot id: P9WL75
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Sec translocon accessory complex subunit YajC
up seq anno feature ids: PRO_0000014139

83332:Rv3102c
gene id: 83332:Rv3102c
uniprot id: O05779
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno comments: ABC transporter
up seq anno comments: Cell division ATP-binding protein FtsE
up seq anno feature ids: PRO_0000432514

83332:Rv0041
gene id: 83332:Rv0041
uniprot id: P9WFV1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Leucine--tRNA ligase
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000152052

83332:Rv0380c
gene id: 83332:Rv0380c
uniprot id: O53715
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: tRNA/rRNA methyltransferase SpoU type

83332:Rv2760c
gene id: 83332:Rv2760c
uniprot id: P9WJ19
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB42
up seq anno feature ids: PRO_0000408083

83332:Rv1233c
gene id: 83332:Rv1233c
uniprot id: O86316
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: DUF4190
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv0870c
gene id: 83332:Rv0870c
uniprot id: I6Y8Z3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Inner membrane component

83332:Rv2419c
gene id: 83332:Rv2419c
uniprot id: P9WIC7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: About 5% of wild-type phosphatase activity.
up seq anno comments: Almost completely abolished phosphatase activity.
up seq anno comments: Disrupts dimerization of the enzyme, which exists as a monomer and has lost its ability to perform dephosphorylation.
up seq anno comments: Glucosyl-3-phosphoglycerate phosphatase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Loss of phosphatase activity.
up seq anno comments: Proton donor/acceptor
up seq anno comments: Tele-phosphohistidine intermediate
up seq anno feature ids: PRO_0000396114

83332:Rv1051c
gene id: 83332:Rv1051c
uniprot id: O53399
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helix-turn-helix

83332:Rv3650
gene id: 83332:Rv3650
uniprot id: I6X7Z8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3232c
gene id: 83332:Rv3232c
uniprot id: O05877
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: GDP-polyphosphate phosphotransferase
up seq anno comments: Loss of GTP-synthesizing activity and lack of autophosphorylation. Does not interact with Ndk.
up seq anno comments: Partial loss of GTP-synthesizing activity and decrease in autophosphorylation. Loss of GTP-synthesizing activity and lack of autophosphorylation; when associated with A-115.
up seq anno comments: Partial loss of GTP-synthesizing activity and decrease in autophosphorylation. Loss of GTP-synthesizing activity and lack of autophosphorylation; when associated with A-247.
up seq anno comments: Partial loss of GTP-synthesizing activity.
up seq anno comments: Phosphohistidine
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000442586

83332:Rv2710
gene id: 83332:Rv2710
uniprot id: P9WGI5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: RNA polymerase sigma factor SigB
up seq anno comments: Sigma-70 factor domain-1
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-3
up seq anno comments: Sigma-70 factor domain-4
up seq anno comments: Sufficient to interact with RbpA
up seq anno feature ids: PRO_0000423644

83332:Rv2063
gene id: 83332:Rv2063
uniprot id: P9WJ85
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Antitoxin MazE7
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000406301

83332:Rv3575c
gene id: 83332:Rv3575c
uniprot id: P96857
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH lacI-type

83332:Rv3051c
gene id: 83332:Rv3051c
uniprot id: P9WH75
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Sequence Conflict
up seq anno labels: Site
up seq anno comments: Allosteric effector binding
up seq anno comments: Cysteine radical intermediate
up seq anno comments: Important for electron transfer
up seq anno comments: Important for hydrogen atom transfer
up seq anno comments: Interacts with thioredoxin/glutaredoxin
up seq anno comments: Proton acceptor
up seq anno comments: Redox-active
up seq anno comments: Ribonucleoside-diphosphate reductase subunit alpha
up seq anno feature ids: PRO_0000187221

83332:Rv2537c
gene id: 83332:Rv2537c
uniprot id: P9WPX7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-dehydroquinate dehydratase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000159910

83332:Rv3384c
gene id: 83332:Rv3384c
uniprot id: O50411
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC46
up seq anno feature ids: PRO_0000407898

83332:Rv3014c
gene id: 83332:Rv3014c
uniprot id: P9WNV1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: BRCT
up seq anno comments: DNA ligase A
up seq anno comments: N6-AMP-lysine intermediate
up seq anno feature ids: PRO_0000161752

83332:Rv0266c
gene id: 83332:Rv0266c
uniprot id: P95223
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Hydantoinase A/oxoprolinase
up seq anno comments: Hydantoinase B/oxoprolinase
up seq anno comments: Hydantoinase/oxoprolinase N-terminal

83332:Rv0237
gene id: 83332:Rv0237
uniprot id: L7N6B0
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Beta-hexosaminidase LpqI
up seq anno comments: Important for catalytic activity
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Nucleophile
up seq anno comments: Proton donor/acceptor
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_5010230425

83332:Rv1453
gene id: 83332:Rv1453
uniprot id: O06807
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: CdaR GGDEF-like
up seq anno comments: Disordered
up seq anno comments: PucR C-terminal helix-turn-helix

83332:Rv3200c
gene id: 83332:Rv3200c
uniprot id: O53346
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: RCK N-terminal

83332:Rv0073
gene id: 83332:Rv0073
uniprot id: P9WQK5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Uncharacterized ABC transporter ATP-binding protein Rv0073
up seq anno feature ids: PRO_0000395860

83332:Rv1489
gene id: 83332:Rv1489
uniprot id: L7N692
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3264c
gene id: 83332:Rv3264c
uniprot id: L7N6A5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Mannose-1-phosphate guanylyltransferase
up seq anno feature ids: PRO_0000456573

83332:Rv2111c
gene id: 83332:Rv2111c
uniprot id: P9WHN5
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Compositionally Biased Region
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Deamidated glutamine; alternate
up seq anno comments: Disordered
up seq anno comments: Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins); alternate
up seq anno comments: Mpa/ARC ATPase binding
up seq anno comments: Prokaryotic ubiquitin-like protein Pup
up seq anno feature ids: PRO_0000383476

83332:Rv1746
gene id: 83332:Rv1746
uniprot id: P9WI75
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Abolishes interaction with Rv1747. Impairs autokinase activity.
up seq anno comments: Decreases interaction with Rv1747.
up seq anno comments: Decreases interaction with Rv1747. Decreases autokinase activity.
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Loss of kinase activity. Abolishes interaction with Rv1747.
up seq anno comments: Phosphoserine; by autocatalysis
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Polar residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknF
up seq anno feature ids: PRO_0000171213

83332:Rv2599
gene id: 83332:Rv2599
uniprot id: P9WL69
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2599
up seq anno feature ids: PRO_0000014143

83332:Rv0393
gene id: 83332:Rv0393
uniprot id: P95201
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HNH nuclease
up seq anno comments: Polar residues

83332:Rv1573
gene id: 83332:Rv1573
uniprot id: O06617
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1938
gene id: 83332:Rv1938
uniprot id: I6YC03
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: AB hydrolase-1
up seq anno comments: Contributes to the formation of an oxyanion binding site for the epoxide oxygen of substrate
up seq anno comments: Epoxide hydrolase B
up seq anno comments: Nucleophile
up seq anno comments: Plays an orienting role for the imidazole group of His-333
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000438586

83332:Rv2429
gene id: 83332:Rv2429
uniprot id: P9WQB5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alkyl hydroperoxide reductase AhpD
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: Interchain (with C-61 in AhpC); in linked form
up seq anno comments: Loss of activity.
up seq anno comments: Loss of activity. Loss of interchain disulfide bond with AhpC.
up seq anno comments: Proton donor
up seq anno comments: Reduced catalytic activity.
up seq anno comments: Reduces protein stability. No effect on catalytic activity.
up seq anno comments: Slightly reduced catalytic activity.
up seq anno feature ids: PRO_0000064507

83332:Rv1401
gene id: 83332:Rv1401
uniprot id: P9WG51
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Lysoplasmalogenase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000201848

83332:Rv3624c
gene id: 83332:Rv3624c
uniprot id: P9WHQ9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Hypoxanthine-guanine phosphoribosyltransferase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000139609

83332:Rv2227
gene id: 83332:Rv2227
uniprot id: P9WLH7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2227
up seq anno feature ids: PRO_0000103980

83332:Rv3437
gene id: 83332:Rv3437
uniprot id: I6YG51
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: DUF2510
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0302
gene id: 83332:Rv0302
uniprot id: O07229
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv2054
gene id: 83332:Rv2054
uniprot id: O86353
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Dienelactone hydrolase

83332:Rv2898c
gene id: 83332:Rv2898c
uniprot id: P9WFM9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: UPF0102 protein Rv2898c
up seq anno feature ids: PRO_0000167363

83332:Rv2547
gene id: 83332:Rv2547
uniprot id: P95006
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB19
up seq anno feature ids: PRO_0000408065

83332:Rv2199c
gene id: 83332:Rv2199c
uniprot id: P9WP45
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable cytochrome c oxidase polypeptide 4
up seq anno feature ids: PRO_0000220019

83332:Rv2395A
gene id: 83332:Rv2395A
uniprot id: V5QPR9
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3564
gene id: 83332:Rv3564
uniprot id: I6YCF5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Acyl-CoA dehydrogenase IpdE2
up seq anno feature ids: PRO_0000452317

83332:Rv1600
gene id: 83332:Rv1600
uniprot id: P9WML7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Histidinol-phosphate aminotransferase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000153397

83332:Rv1627c
gene id: 83332:Rv1627c
uniprot id: O06144
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thiolase N-terminal

83332:Rv1281c
gene id: 83332:Rv1281c
uniprot id: P9WQJ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter 1
up seq anno comments: ABC transporter 2
up seq anno comments: Uncharacterized ABC transporter ATP-binding protein Rv1281c
up seq anno feature ids: PRO_0000093259

83332:Rv1593c
gene id: 83332:Rv1593c
uniprot id: O06597
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nudix hydrolase

83332:Rv0397A
gene id: 83332:Rv0397A
uniprot id: I6Y3N9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010179206

83332:Rv0050
gene id: 83332:Rv0050
uniprot id: P71707
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Acyl-ester intermediate; for transpeptidase activity
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Penicillin-binding protein 1A
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Proton donor; for transglycosylase activity
up seq anno comments: Transglycosylase
up seq anno comments: Transpeptidase
up seq anno feature ids: PRO_0000421124

83332:Rv2459
gene id: 83332:Rv2459
uniprot id: P9WJW9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Drug efflux pump JefA
up seq anno comments: Helical
up seq anno feature ids: PRO_0000390685

83332:Rv1101c
gene id: 83332:Rv1101c
uniprot id: P9WFM3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative transport protein Rv1101c
up seq anno feature ids: PRO_0000148318

83332:Rv1421
gene id: 83332:Rv1421
uniprot id: P9WFQ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Nucleotide-binding protein Rv1421
up seq anno feature ids: PRO_0000107732

83332:Rv0052
gene id: 83332:Rv0052
uniprot id: I6Y6S3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DJ-1/PfpI

83332:Rv0914c
gene id: 83332:Rv0914c
uniprot id: I6XWJ8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thiolase C-terminal
up seq anno comments: Thiolase N-terminal

83332:Rv3117
gene id: 83332:Rv3117
uniprot id: P9WHF9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: Putative thiosulfate sulfurtransferase
up seq anno comments: Rhodanese 1
up seq anno comments: Rhodanese 2
up seq anno feature ids: PRO_0000139415

83332:Rv1244
gene id: 83332:Rv1244
uniprot id: O50459
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: ABC-type glycine betaine transport system substrate-binding
up seq anno feature ids: PRO_5010295864

83332:Rv0882
gene id: 83332:Rv0882
uniprot id: P9WKQ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0882
up seq anno feature ids: PRO_0000014081

83332:Rv1077
gene id: 83332:Rv1077
uniprot id: P9WP51
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Modified Residue
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable cystathionine beta-synthase Rv1077
up seq anno feature ids: PRO_0000395885

83332:Rv3798
gene id: 83332:Rv3798
uniprot id: P9WKH7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Transposase for insertion sequence element IS1557
up seq anno feature ids: PRO_0000075450

83332:Rv0314c
gene id: 83332:Rv0314c
uniprot id: O07241
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv1899c
gene id: 83332:Rv1899c
uniprot id: P9WK29
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Macro
up seq anno comments: Uncharacterized protein Rv1899c
up seq anno feature ids: PRO_0000089202

83332:Rv1538c
gene id: 83332:Rv1538c
uniprot id: P9WPX5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Asparaginase/glutaminase
up seq anno comments: L-asparaginase
up seq anno comments: O-isoaspartyl threonine intermediate
up seq anno feature ids: PRO_0000171084

83332:Rv3245c
gene id: 83332:Rv3245c
uniprot id: P9WGK9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Loss of autophosphorylation. Partially complements an M.smegmatis mtrB disruption, cells are still filamentous and bulged but the protein targets to septa.
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Pro residues
up seq anno comments: Sensor histidine kinase MtrB
up seq anno feature ids: PRO_0000074809

83332:Rv2720
gene id: 83332:Rv2720
uniprot id: P9WHR7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: Cleavage; by autolysis
up seq anno comments: Disordered
up seq anno comments: For autocatalytic cleavage activity
up seq anno comments: H-T-H motif
up seq anno comments: LexA repressor
up seq anno feature ids: PRO_0000170059

83332:Rv0455c
gene id: 83332:Rv0455c
uniprot id: O53740
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5030174834

83332:Rv3587c
gene id: 83332:Rv3587c
uniprot id: O53572
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv3061c
gene id: 83332:Rv3061c
uniprot id: I6X654
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv2209
gene id: 83332:Rv2209
uniprot id: P9WLI3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2209
up seq anno feature ids: PRO_0000103977

83332:Rv3395c
gene id: 83332:Rv3395c
uniprot id: P9WKZ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv3395c
up seq anno feature ids: PRO_0000104116

83332:Rv0277c
gene id: 83332:Rv0277c
uniprot id: P9WF85
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC25
up seq anno feature ids: PRO_0000407884

83332:Rv0286
gene id: 83332:Rv0286
uniprot id: P9WI43
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: PPE family protein PPE4
up seq anno feature ids: PRO_0000378475

83332:Rv3211
gene id: 83332:Rv3211
uniprot id: O05855
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: DEAD-box RNA helicase Q
up seq anno comments: Disordered
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno comments: Polar residues
up seq anno comments: Q motif

83332:Rv1125
gene id: 83332:Rv1125
uniprot id: O06577
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: O-acyltransferase WSD1 C-terminal

83332:Rv0083
gene id: 83332:Rv0083
uniprot id: P9WIW3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0083
up seq anno feature ids: PRO_0000118049

83332:Rv0575c
gene id: 83332:Rv0575c
uniprot id: O53772
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding

83332:Rv3710
gene id: 83332:Rv3710
uniprot id: P9WQB3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-isopropylmalate synthase
up seq anno comments: Disordered
up seq anno comments: Linker
up seq anno comments: N-terminal domain
up seq anno comments: Pyruvate carboxyltransferase
up seq anno comments: Regulatory domain
up seq anno comments: Required for the condensation reaction. Not required to bind substrate
up seq anno comments: Subdomain I
up seq anno comments: Subdomain II
up seq anno comments: VNTR1
up seq anno comments: VNTR2
up seq anno feature ids: PRO_0000140436

83332:Rv0941c
gene id: 83332:Rv0941c
uniprot id: P71568
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: STAS

83332:Rv2121c
gene id: 83332:Rv2121c
uniprot id: P9WMN1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP phosphoribosyltransferase
up seq anno feature ids: PRO_0000151857

83332:Rv0751c
gene id: 83332:Rv0751c
uniprot id: P9WNY5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable 3-hydroxyisobutyrate dehydrogenase
up seq anno feature ids: PRO_0000173056

83332:Rv3884c
gene id: 83332:Rv3884c
uniprot id: P9WPH7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: ESX-2 secretion system protein EccA2
up seq anno feature ids: PRO_0000063051

83332:Rv0403c
gene id: 83332:Rv0403c
uniprot id: P9WJT5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport accessory protein MmpS1
up seq anno feature ids: PRO_0000216151

83332:Rv3334
gene id: 83332:Rv3334
uniprot id: O53384
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH merR-type

83332:Rv1064c
gene id: 83332:Rv1064c
uniprot id: P9WK57
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LpqV
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018133

83332:Rv2765
gene id: 83332:Rv2765
uniprot id: I6XF92
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Dienelactone hydrolase

83332:Rv2238c
gene id: 83332:Rv2238c
uniprot id: P9WIE3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alkyl hydroperoxide reductase E
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_0000135148

83332:Rv2730
gene id: 83332:Rv2730
uniprot id: I6Y1K4
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv3083
gene id: 83332:Rv3083
uniprot id: P9WNF7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Putative FAD-containing monooxygenase MymA
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000420876

83332:Rv2066
gene id: 83332:Rv2066
uniprot id: P9WGB3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Cobalamin biosynthesis protein CobIJ
up seq anno comments: Disordered
up seq anno comments: Precorrin-2 C20-methyltransferase
up seq anno comments: Precorrin-3 methylase
up seq anno feature ids: PRO_0000150390

83332:Rv2908c
gene id: 83332:Rv2908c
uniprot id: P9WFM7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno comments: KH
up seq anno comments: RNA-binding protein KhpA
up seq anno comments: Removed
up seq anno feature ids: PRO_0000163231

83332:Rv2557
gene id: 83332:Rv2557
uniprot id: P9WLA5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2557
up seq anno feature ids: PRO_0000104035

83332:Rv3753c
gene id: 83332:Rv3753c
uniprot id: O69720
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Protein Rv3753c
up seq anno comments: Removed
up seq anno feature ids: PRO_0000456391

83332:Rv0984
gene id: 83332:Rv0984
uniprot id: O53897
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MoaB/Mog

83332:Rv2734
gene id: 83332:Rv2734
uniprot id: I6YA42
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1463
gene id: 83332:Rv1463
uniprot id: O53154
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv0093c
gene id: 83332:Rv0093c
uniprot id: P9WM69
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0093c
up seq anno feature ids: PRO_0000103666

83332:Rv1759c
gene id: 83332:Rv1759c
uniprot id: P9WIG5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: WAG22 antigen
up seq anno feature ids: PRO_0000023574

83332:Rv1637c
gene id: 83332:Rv1637c
uniprot id: O06154
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv1291c
gene id: 83332:Rv1291c
uniprot id: P9WM33
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1291c
up seq anno feature ids: PRO_0000103791

83332:Rv2135c
gene id: 83332:Rv2135c
uniprot id: O06240
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0152c
gene id: 83332:Rv0152c
uniprot id: Q79G05
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: PE-PPE

83332:Rv2472
gene id: 83332:Rv2472
uniprot id: O53199
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1114
gene id: 83332:Rv1114
uniprot id: P9WF73
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC32
up seq anno feature ids: PRO_0000407889

83332:Rv1960c
gene id: 83332:Rv1960c
uniprot id: P9WIJ7
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Region
up seq anno comments: Antitoxin ParD1
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000216353

83332:Rv0065
gene id: 83332:Rv0065
uniprot id: P9WFC1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribonuclease VapC1
up seq anno feature ids: PRO_0000407864

83332:Rv0927c
gene id: 83332:Rv0927c
uniprot id: P9WGQ5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv0927c
up seq anno feature ids: PRO_0000415507

83332:Rv3132c
gene id: 83332:Rv3132c
uniprot id: P9WGK3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-binding domain
up seq anno comments: Can form a disulfide bond; when associated with C-440. Decreased autophosphorylation; when associated with C-524. Loss of autophosphorylation; when associated with C-440 or C-440 and C-524.
up seq anno comments: Can form a disulfide bond; when associated with C-537. Loss of autophosphorylation; when associated with C-524 or C-524 and C-537.
up seq anno comments: Decreased autophosphorylation when CO- or NO-bound, none in the deoxy or O(2)-bound state, protein more easily oxidized to Fe(3+) state.
up seq anno comments: GAF 1
up seq anno comments: GAF 2
up seq anno comments: Histidine acceptor domain
up seq anno comments: Histidine kinase
up seq anno comments: Isolated kinase core no longer forms dimers, autophosphorylation unaffected. Decreased autophosphorylation; when associated with C-537. Loss of autophosphorylation; when associated with C-440 or C-440 and C-537.
up seq anno comments: N-acetylthreonine
up seq anno comments: No autophosphorylation activity no matter the bound gaseous ligand, protein more easily oxidized to Fe(3+) state.
up seq anno comments: No autophosphorylation activity no matter the bound gaseous ligand.
up seq anno comments: No autophosphorylation when Fe(2+) protein is bound to CO or NO; no change in autophosphorylation of deoxy-protein. No change in auto-oxidation, slightly higher affinity for O(2) and CO.
up seq anno comments: No autophosphorylation, no transfer to DevR (DosR).
up seq anno comments: No autophosphorylation.
up seq anno comments: No autophosphorylation. Isolated kinase core binds ATP.
up seq anno comments: No change in autophosphorylation when NO-bound, decreased autophosphorylation in deoxy or CO-bound state, slightly increased activity in O(2)-bound state.
up seq anno comments: No change in autophosphorylation when NO-bound, loss of autophosphorylation in deoxy or CO-bound state.
up seq anno comments: No change in autophosphorylation when deoxy or NO-bound, decreased autophosphorylation when CO-bound, increased activity in O(2)-bound state.
up seq anno comments: No change in heme binding.
up seq anno comments: No change in phosphorylation.
up seq anno comments: Oxygen sensor histidine kinase response regulator DevS/DosS
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Removed
up seq anno comments: Weaker than wild-type heme binding.
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000392623

83332:Rv1751
gene id: 83332:Rv1751
uniprot id: O65936
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding

83332:Rv1169c
gene id: 83332:Rv1169c
uniprot id: Q79FR5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Esterase PE11
up seq anno comments: PE
up seq anno feature ids: PRO_0000451088

83332:Rv0718
gene id: 83332:Rv0718
uniprot id: P9WH27
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein uS8
up seq anno feature ids: PRO_0000126448

83332:Rv3809c
gene id: 83332:Rv3809c
uniprot id: P9WIQ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: UDP-galactopyranose mutase
up seq anno feature ids: PRO_0000420735

83332:Rv1909c
gene id: 83332:Rv1909c
uniprot id: P9WN87
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: DNA-binding
up seq anno comments: Dimerization
up seq anno comments: Transcriptional regulator FurA
up seq anno feature ids: PRO_0000095562

83332:Rv2076c
gene id: 83332:Rv2076c
uniprot id: P9WLL3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2076c
up seq anno feature ids: PRO_0000103947

83332:Rv1550
gene id: 83332:Rv1550
uniprot id: P9WQ53
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Putative fatty-acid--CoA ligase fadD11
up seq anno feature ids: PRO_0000193133

83332:Rv3255c
gene id: 83332:Rv3255c
uniprot id: O05898
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Phosphomannose isomerase type I catalytic

83332:Rv1723
gene id: 83332:Rv1723
uniprot id: P71981
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Beta-lactamase-related
up seq anno comments: Disordered

83332:Rv2219
gene id: 83332:Rv2219
uniprot id: P9WLI1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2219
up seq anno feature ids: PRO_0000014126

83332:Rv3072c
gene id: 83332:Rv3072c
uniprot id: P95086
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Luciferase-like
up seq anno comments: Polar residues

83332:Rv0355c
gene id: 83332:Rv0355c
uniprot id: I6Y7L4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE

83332:Rv1138c
gene id: 83332:Rv1138c
uniprot id: O06538
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding

83332:Rv0624
gene id: 83332:Rv0624
uniprot id: P9WF77
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC30
up seq anno feature ids: PRO_0000221199

83332:Rv3757c
gene id: 83332:Rv3757c
uniprot id: O69723
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv2876
gene id: 83332:Rv2876
uniprot id: P9WL39
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2876
up seq anno feature ids: PRO_0000104089

83332:Rv0586
gene id: 83332:Rv0586
uniprot id: P9WMG5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH gntR-type
up seq anno comments: HTH-type transcriptional regulator Mce2R
up seq anno feature ids: PRO_0000050699

83332:Rv3720
gene id: 83332:Rv3720
uniprot id: O69687
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable fatty acid methyltransferase Rv3720
up seq anno feature ids: PRO_0000432511

83332:Rv0953c
gene id: 83332:Rv0953c
uniprot id: P9WKN5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0953c
up seq anno feature ids: PRO_0000103749

83332:Rv0764c
gene id: 83332:Rv0764c
uniprot id: P9WPP9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Sterol 14alpha-demethylase
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052017

83332:Rv0413
gene id: 83332:Rv0413
uniprot id: P9WIX9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Nudix box
up seq anno comments: Nudix hydrolase
up seq anno comments: Putative 8-oxo-dGTP diphosphatase 3
up seq anno feature ids: PRO_0000391777

83332:Rv1254
gene id: 83332:Rv1254
uniprot id: Q11064
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Acyltransferase 3
up seq anno comments: Helical

83332:Rv3277
gene id: 83332:Rv3277
uniprot id: P96882
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: GtrA/DPMS transmembrane
up seq anno comments: Helical

83332:Rv1076
gene id: 83332:Rv1076
uniprot id: O53424
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 20% loss of activity.
up seq anno comments: 85% loss of activity.
up seq anno comments: Complete loss of activity.
up seq anno comments: Esterase LipU
up seq anno feature ids: PRO_0000448882

83332:Rv1921c
gene id: 83332:Rv1921c
uniprot id: O53963
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno feature ids: PRO_5039706173

83332:Rv2248
gene id: 83332:Rv2248
uniprot id: P9WLG5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2248
up seq anno feature ids: PRO_0000103990

83332:Rv2779c
gene id: 83332:Rv2779c
uniprot id: O33321
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH asnC-type

83332:Rv3093c
gene id: 83332:Rv3093c
uniprot id: O05772
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv1733c
gene id: 83332:Rv1733c
uniprot id: P9WLS9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable membrane protein Rv1733c
up seq anno feature ids: PRO_0000392906

83332:Rv2919c
gene id: 83332:Rv2919c
uniprot id: P9WN31
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Nitrogen regulatory protein P-II
up seq anno comments: O-UMP-tyrosine
up seq anno feature ids: PRO_0000139779

83332:Rv2569c
gene id: 83332:Rv2569c
uniprot id: P9WL93
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv2569c
up seq anno feature ids: PRO_0000104047

83332:Rv2746c
gene id: 83332:Rv2746c
uniprot id: P9WPG3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable phosphatidylglycerophosphate synthase
up seq anno feature ids: PRO_0000393110

83332:Rv0470c
gene id: 83332:Rv0470c
uniprot id: P9WPB3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cyclopropane mycolic acid synthase 3
up seq anno comments: Loss of phosphorylation; when associated with A-168.
up seq anno comments: Loss of phosphorylation; when associated with A-183.
up seq anno comments: N-acetylserine
up seq anno comments: Phosphothreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000398358

83332:Rv3406
gene id: 83332:Rv3406
uniprot id: P9WKZ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alpha-ketoglutarate-dependent sulfate ester dioxygenase
up seq anno feature ids: PRO_0000104125

83332:Rv0645c
gene id: 83332:Rv0645c
uniprot id: P9WPB1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Mycolic acid methyltransferase MmaA1
up seq anno feature ids: PRO_0000096504

83332:Rv2317
gene id: 83332:Rv2317
uniprot id: L7N652
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv3593
gene id: 83332:Rv3593
uniprot id: O06155
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Beta-lactamase class A catalytic
up seq anno comments: Disordered
up seq anno comments: ORF 12 gene product N-terminal
up seq anno feature ids: PRO_5039162583

83332:Rv3223c
gene id: 83332:Rv3223c
uniprot id: P9WGH9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: ECF RNA polymerase sigma factor SigH
up seq anno comments: H-T-H motif
up seq anno comments: No in vitro phosphorylation by PknB; when associated with A-106.
up seq anno comments: No in vitro phosphorylation by PknB; when associated with A-26.
up seq anno comments: Polymerase core binding
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000094004

83332:Rv1802
gene id: 83332:Rv1802
uniprot id: P9WI07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE30
up seq anno feature ids: PRO_0000217848

83332:Rv0104
gene id: 83332:Rv0104
uniprot id: P9WM61
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0104
up seq anno feature ids: PRO_0000103675

83332:Rv0472c
gene id: 83332:Rv0472c
uniprot id: P9WMD9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0472c
up seq anno feature ids: PRO_0000382633

83332:Rv1869c
gene id: 83332:Rv1869c
uniprot id: P95146
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD/NAD(P)-binding
up seq anno comments: Reductase C-terminal

83332:Rv3033
gene id: 83332:Rv3033
uniprot id: I6YAY5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: DUF4333
up seq anno comments: DUF4333 domain-containing protein
up seq anno feature ids: PRO_5039316021

83332:Rv1648
gene id: 83332:Rv1648
uniprot id: P94983
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0256c
gene id: 83332:Rv0256c
uniprot id: P9WI47
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Does not affect interaction with NCF2 and ROS production.
up seq anno comments: Does not interact with NCF2 and cannot inhibit ROS production.
up seq anno comments: Leucine zipper motif
up seq anno comments: Nuclear localization signal
up seq anno comments: PPE
up seq anno comments: PPE family protein PPE2
up seq anno comments: Pro residues
up seq anno comments: SH3-like
up seq anno feature ids: PRO_0000378473

83332:Rv2866
gene id: 83332:Rv2866
uniprot id: O33348
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Toxin RelG
up seq anno feature ids: PRO_0000406200

83332:Rv1971
gene id: 83332:Rv1971
uniprot id: O53972
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mce/MlaD

83332:Rv0075
gene id: 83332:Rv0075
uniprot id: O53620
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Aminotransferase class I/classII

83332:Rv0592
gene id: 83332:Rv0592
uniprot id: I6WYT7
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv1769
gene id: 83332:Rv1769
uniprot id: O06802
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alanine racemase N-terminal

83332:Rv2259
gene id: 83332:Rv2259
uniprot id: O53533
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Enoyl reductase (ER)

83332:Rv1342c
gene id: 83332:Rv1342c
uniprot id: P9WM19
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv1342c
up seq anno feature ids: PRO_0000103814

83332:Rv2627c
gene id: 83332:Rv2627c
uniprot id: P9WL67
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2627c
up seq anno feature ids: PRO_0000392935

83332:Rv0728c
gene id: 83332:Rv0728c
uniprot id: I6WZ71
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
up seq anno comments: D-isomer specific 2-hydroxyacid dehydrogenase catalytic

83332:Rv3822
gene id: 83332:Rv3822
uniprot id: O07801
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Helical
up seq anno comments: Lack of activity.
up seq anno comments: PE-PPE
up seq anno comments: Periplasmic
up seq anno comments: SL1278 acyltransferase Chp1
up seq anno feature ids: PRO_0000432823

83332:Rv1597
gene id: 83332:Rv1597
uniprot id: O06593
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase type 11

83332:Rv2446c
gene id: 83332:Rv2446c
uniprot id: O53173
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2086
gene id: 83332:Rv2086
uniprot id: P64937
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2086
up seq anno feature ids: PRO_0000103958

83332:Rv1560
gene id: 83332:Rv1560
uniprot id: P9WLU3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Antitoxin VapB11
up seq anno feature ids: PRO_0000103881

83332:Rv3267
gene id: 83332:Rv3267
uniprot id: P96872
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Cell envelope-related transcriptional attenuator
up seq anno comments: Disordered
up seq anno comments: LytR/CpsA/Psr regulator C-terminal

83332:Rv2265
gene id: 83332:Rv2265
uniprot id: P9WLG3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2265
up seq anno feature ids: PRO_0000103991

83332:Rv2229c
gene id: 83332:Rv2229c
uniprot id: P9WLH3
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno comments: Uncharacterized protein Rv2229c
up seq anno feature ids: PRO_0000103983

83332:Rv0995
gene id: 83332:Rv0995
uniprot id: O05578
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase

83332:Rv1659
gene id: 83332:Rv1659
uniprot id: P9WPY7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Argininosuccinate lyase
up seq anno feature ids: PRO_0000137793

83332:Rv2889c
gene id: 83332:Rv2889c
uniprot id: P9WNM1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Elongation factor Ts
up seq anno comments: Involved in Mg(2+) ion dislocation from EF-Tu
up seq anno feature ids: PRO_0000161160

83332:Rv3767c
gene id: 83332:Rv3767c
uniprot id: P9WFH5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv3767c
up seq anno feature ids: PRO_0000361240

83332:Rv0634c
gene id: 83332:Rv0634c
uniprot id: I6Y4A5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv0963c
gene id: 83332:Rv0963c
uniprot id: P9WKM7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0963c
up seq anno feature ids: PRO_0000103759

83332:Rv1809
gene id: 83332:Rv1809
uniprot id: P9WI03
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE33
up seq anno feature ids: PRO_0000379589

83332:Rv0428c
gene id: 83332:Rv0428c
uniprot id: P96274
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable histone acetyltransferase Rv0428c
up seq anno feature ids: PRO_0000456584

83332:Rv1264
gene id: 83332:Rv1264
uniprot id: P9WMU9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 7-fold increase in holoenzyme adenylyl cyclase activity at pH 8.0.
up seq anno comments: Almost complete loss of adenylyl cyclase activity in the catalytic fragment.
up seq anno comments: Catalytic domain
up seq anno comments: Guanylate cyclase
up seq anno comments: Higher activity above pH 7.0.
up seq anno comments: Linker
up seq anno comments: Loss of adenylyl cyclase activity in the catalytic fragment.
up seq anno comments: Loss of pH regulation.
up seq anno comments: N-acetylthreonine
up seq anno comments: No change in holoenzyme activity.
up seq anno comments: Obviates pH regulation.
up seq anno comments: Partially relieves high pH inhibition.
up seq anno comments: Regulatory domain
up seq anno comments: Removed
up seq anno comments: Retains 10% adenylyl cyclase activity in the catalytic fragment.
up seq anno comments: Shifts activation towards acidic pH.
up seq anno comments: pH-sensitive adenylate cyclase Rv1264
up seq anno feature ids: PRO_0000074131

83332:Rv0249c
gene id: 83332:Rv0249c
uniprot id: O53671
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1437
gene id: 83332:Rv1437
uniprot id: P9WID1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Phosphoglycerate kinase
up seq anno feature ids: PRO_0000145973

83332:Rv1608c
gene id: 83332:Rv1608c
uniprot id: P9WID9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: Putative peroxiredoxin Rv1608c
up seq anno comments: Redox-active
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_0000396097

83332:Rv1092c
gene id: 83332:Rv1092c
uniprot id: P9WPA7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Pantothenate kinase
up seq anno feature ids: PRO_0000194439

83332:Rv1931c
gene id: 83332:Rv1931c
uniprot id: P95283
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH araC/xylS-type
up seq anno comments: HTH-type transcriptional regulator Rv1931c
up seq anno feature ids: PRO_0000438537

83332:Rv2789c
gene id: 83332:Rv2789c
uniprot id: I6XFA9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv1268c
gene id: 83332:Rv1268c
uniprot id: P9WM47
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1268c
up seq anno feature ids: PRO_0000014087

83332:Rv1743
gene id: 83332:Rv1743
uniprot id: P9WI77
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Lack of kinase activity.
up seq anno comments: Phosphoserine; by autocatalysis
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Pro residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknE
up seq anno feature ids: PRO_0000171211

83332:Rv3452
gene id: 83332:Rv3452
uniprot id: O06319
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: Nucleophile
up seq anno comments: Phospholipase Culp4
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_5010306774

83332:Rv3416
gene id: 83332:Rv3416
uniprot id: P9WF41
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Turn
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: Fully oxidized protein.
up seq anno comments: Fully reduced protein.
up seq anno comments: No 4Fe-4S cluster assembly, does not complement growth defects; when associated with A-23; A-56 and A-62.
up seq anno comments: No 4Fe-4S cluster assembly, does not complement growth defects; when associated with A-33; A-53 and A-56.
up seq anno comments: No 4Fe-4S cluster assembly, does not complement growth defects; when associated with A-33; A-53 and A-62.
up seq anno comments: No 4Fe-4S cluster assembly, does not complement growth defects; when associated with A-53; A-56 and A-62.
up seq anno comments: Redox- and pH-responsive transcriptional regulator WhiB3
up seq anno feature ids: PRO_0000420382

83332:Rv0656c
gene id: 83332:Rv0656c
uniprot id: P9WFB5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC6
up seq anno feature ids: PRO_0000407869

83332:Rv2416c
gene id: 83332:Rv2416c
uniprot id: P9WFK7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes catalytic activity on AG substrates.
up seq anno comments: Abolishes catalytic activity on AG substrates. Abolishes catalytic activity on HupB.
up seq anno comments: Decreases catalytic activity on AG substrates, leads to a change in the number of acetylated sites.
up seq anno comments: N-acetyltransferase
up seq anno comments: N-acetyltransferase Eis
up seq anno comments: Nearly abolishes catalytic activity on AG substrates.
up seq anno comments: No effect on catalytic activity on AG substrates. Prevents artifactual CoA adduct formation during crystallization.
up seq anno comments: Proton acceptor; via carboxylate
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000220262

83332:Rv2385
gene id: 83332:Rv2385
uniprot id: Q79FE8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alpha/beta hydrolase fold-3

83332:Rv3606c
gene id: 83332:Rv3606c
uniprot id: P9WNC7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
up seq anno feature ids: PRO_0000168255

83332:Rv0116c
gene id: 83332:Rv0116c
uniprot id: O53638
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: L,D-TPase catalytic
up seq anno comments: L,D-transpeptidase 1
up seq anno comments: Nucleophile
up seq anno comments: Proton donor/acceptor
up seq anno comments: covalent
up seq anno feature ids: PRO_0000430332

83332:Rv3235
gene id: 83332:Rv3235
uniprot id: O05880
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv0482
gene id: 83332:Rv0482
uniprot id: B5AFK3
uniprot id: P9WJL9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: FAD-binding PCMH-type
up seq anno comments: Proton donor
up seq anno comments: UDP-N-acetylenolpyruvoylglucosamine reductase
up seq anno feature ids: PRO_0000179230

83332:Rv1879
gene id: 83332:Rv1879
uniprot id: O07751
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amidohydrolase-related

83332:Rv3043c
gene id: 83332:Rv3043c
uniprot id: P9WP71
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 1'-histidyl-3'-tyrosine (His-Tyr)
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Probable cytochrome c oxidase subunit 1
up seq anno comments: Removed
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000183443

83332:Rv0299
gene id: 83332:Rv0299
uniprot id: O07226
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Toxin Rv0299
up seq anno feature ids: PRO_0000406883

83332:Rv3420c
gene id: 83332:Rv3420c
uniprot id: I6YG32
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase
up seq anno comments: N-alpha-acetyltransferase RimI
up seq anno feature ids: PRO_0000438820

83332:Rv3918c
gene id: 83332:Rv3918c
uniprot id: Q1LVD4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: AAA
up seq anno comments: Disordered

83332:Rv2274A
gene id: 83332:Rv2274A
uniprot id: P0CL60
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin MazE8
up seq anno feature ids: PRO_0000406302

83332:Rv3499c
gene id: 83332:Rv3499c
uniprot id: I6YC99
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv0602c
gene id: 83332:Rv0602c
uniprot id: O07776
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: 4-aspartylphosphate
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Response regulatory
up seq anno comments: Transcriptional regulatory protein TcrA
up seq anno feature ids: PRO_0000391082

83332:Rv1779c
gene id: 83332:Rv1779c
uniprot id: O53930
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Coiled-Coil
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1789
gene id: 83332:Rv1789
uniprot id: Q79FK6
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: PPE family protein PPE26
up seq anno feature ids: PRO_0000437938

83332:Rv1448c
gene id: 83332:Rv1448c
uniprot id: P9WG33
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Schiff-base intermediate with substrate
up seq anno comments: Transaldolase
up seq anno feature ids: PRO_0000173636

83332:Rv2271
gene id: 83332:Rv2271
uniprot id: P9WLF7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2271
up seq anno feature ids: PRO_0000103997

83332:Rv1430
gene id: 83332:Rv1430
uniprot id: L7N697
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Esterase PE16
up seq anno comments: Helical
up seq anno comments: Linker
up seq anno comments: Loss of activity.
up seq anno comments: PE
up seq anno comments: PE-PPE
up seq anno feature ids: PRO_0000448332

83332:Rv2638
gene id: 83332:Rv2638
uniprot id: I6X4W0
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Putative anti-anti-sigma factor Rv2638
up seq anno comments: STAS
up seq anno feature ids: PRO_0000451031

83332:Rv1278
gene id: 83332:Rv1278
uniprot id: P9WM41
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1278
up seq anno feature ids: PRO_0000103782

83332:Rv3832c
gene id: 83332:Rv3832c
uniprot id: P96246
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase type 11

83332:Rv0739
gene id: 83332:Rv0739
uniprot id: P9WKS1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0739
up seq anno feature ids: PRO_0000103716

83332:Rv2456c
gene id: 83332:Rv2456c
uniprot id: P9WJX1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter Rv2456c
up seq anno feature ids: PRO_0000390684

83332:Rv2097c
gene id: 83332:Rv2097c
uniprot id: P9WNU7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Abolishes pupylation.
up seq anno comments: Proton acceptor
up seq anno comments: Pup--protein ligase
up seq anno feature ids: PRO_0000103966

83332:Rv2275
gene id: 83332:Rv2275
uniprot id: P9WPF9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: Complete loss of cYY-forming activity.
up seq anno comments: Could be involved in aa-tRNA binding
up seq anno comments: Could have a critical role in the catalytic mechanism
up seq anno comments: Cyclo(L-tyrosyl-L-tyrosyl) synthase
up seq anno comments: Disordered
up seq anno comments: Nucleophile
up seq anno comments: Small but detectable amount of cYY-forming activity.
up seq anno comments: Small but detectable amount of catalytic activity (200-fold decrease).
up seq anno feature ids: PRO_0000423356

83332:Rv2929
gene id: 83332:Rv2929
uniprot id: P9WL13
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2929
up seq anno feature ids: PRO_0000014149

83332:Rv2240c
gene id: 83332:Rv2240c
uniprot id: P9WLG7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2240c
up seq anno feature ids: PRO_0000103989

83332:Rv0178
gene id: 83332:Rv0178
uniprot id: O07422
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv2757c
gene id: 83332:Rv2757c
uniprot id: P9WF91
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC21
up seq anno feature ids: PRO_0000407880

83332:Rv2574
gene id: 83332:Rv2574
uniprot id: P9WL87
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2574
up seq anno feature ids: PRO_0000104054

83332:Rv1671
gene id: 83332:Rv1671
uniprot id: O53918
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2900c
gene id: 83332:Rv2900c
uniprot id: P9WJP9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized oxidoreductase Rv2900c
up seq anno feature ids: PRO_0000063243

83332:Rv3777
gene id: 83332:Rv3777
uniprot id: P72043
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Enoyl reductase (ER)

83332:Rv3434c
gene id: 83332:Rv3434c
uniprot id: I6YC44
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3608c
gene id: 83332:Rv3608c
uniprot id: P9WND1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Dihydropteroate synthase
up seq anno comments: Pterin-binding
up seq anno feature ids: PRO_0000168215

83332:Rv0120c
gene id: 83332:Rv0120c
uniprot id: P9WNM9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Elongation factor G-like protein
up seq anno comments: G1
up seq anno comments: G2
up seq anno comments: G3
up seq anno comments: G4
up seq anno comments: G5
up seq anno comments: tr-type G
up seq anno feature ids: PRO_0000091276

83332:Rv1983
gene id: 83332:Rv1983
uniprot id: P9WIF1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE cleavage protein A
up seq anno feature ids: PRO_0000216166

83332:Rv0439c
gene id: 83332:Rv0439c
uniprot id: O53726
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1306
gene id: 83332:Rv1306
uniprot id: P9WPV5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ATP synthase subunit b
up seq anno comments: Helical
up seq anno feature ids: PRO_0000082381

83332:Rv0085
gene id: 83332:Rv0085
uniprot id: P9WM75
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0085
up seq anno feature ids: PRO_0000103660

83332:Rv1798
gene id: 83332:Rv1798
uniprot id: P9WPI1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ESX-5 secretion system protein EccA5
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000063046

83332:Rv1274
gene id: 83332:Rv1274
uniprot id: P9WK53
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine; alternate
up seq anno comments: Putative lipoprotein LprB
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018138

83332:Rv0262c
gene id: 83332:Rv0262c
uniprot id: P9WQG9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Aminoglycoside 2'-N-acetyltransferase
up seq anno comments: N-acetyltransferase
up seq anno feature ids: PRO_0000064412

83332:Rv1103c
gene id: 83332:Rv1103c
uniprot id: O53451
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin MazE3
up seq anno feature ids: PRO_0000406298

83332:Rv1618
gene id: 83332:Rv1618
uniprot id: O06135
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA thioesterase II

83332:Rv2799
gene id: 83332:Rv2799
uniprot id: I6XFB7
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1942c
gene id: 83332:Rv1942c
uniprot id: P95272
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable endoribonuclease MazF5
up seq anno feature ids: PRO_0000406307

83332:Rv3229c
gene id: 83332:Rv3229c
uniprot id: P9WNZ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Enhances catalytic activity and stability.
up seq anno comments: NADPH-dependent stearoyl-CoA 9-desaturase
up seq anno feature ids: PRO_0000392677

83332:Rv1754c
gene id: 83332:Rv1754c
uniprot id: O06790
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: DUF4185
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv2596
gene id: 83332:Rv2596
uniprot id: P9WF61
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC40
up seq anno feature ids: PRO_0000014142

83332:Rv3464
gene id: 83332:Rv3464
uniprot id: P9WN65
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: dTDP-glucose 4,6-dehydratase
up seq anno feature ids: PRO_0000395348

83332:Rv1568
gene id: 83332:Rv1568
uniprot id: P9WQ81
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
up seq anno comments: Does not show detectable activity at 335 nm with SAM, even up to concentrations of 3 mM, and shows approximately 70% reduced activity with high concentrations of DAPA (0.5 mM).
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
up seq anno feature ids: PRO_0000120374

83332:Rv2426c
gene id: 83332:Rv2426c
uniprot id: P71922
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA+ ATPase

83332:Rv3619c
gene id: 83332:Rv3619c
uniprot id: P0DOA6
uniprot id: P0DOA7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: ESAT-6-like protein EsxI
up seq anno comments: ESAT-6-like protein EsxV
up seq anno feature ids: PRO_0000167800
up seq anno feature ids: PRO_0000436928

83332:Rv3789
gene id: 83332:Rv3789
uniprot id: P9WMS9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Arabinogalactan biosynthesis recruiting protein Rv3789
up seq anno comments: Cytoplasmic
up seq anno comments: Helical
up seq anno comments: Periplasmic
up seq anno feature ids: PRO_0000212257

83332:Rv0493c
gene id: 83332:Rv0493c
uniprot id: P9WKU7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0493c
up seq anno feature ids: PRO_0000103694

83332:Rv0786c
gene id: 83332:Rv0786c
uniprot id: P71839
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein Rv0786c
up seq anno feature ids: PRO_0000455999

83332:Rv2544
gene id: 83332:Rv2544
uniprot id: P9WK79
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppB
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000361671

83332:Rv3539
gene id: 83332:Rv3539
uniprot id: P9WHX5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE-PPE
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized PPE family protein PPE63
up seq anno feature ids: PRO_0000379118

83332:Rv2828A
gene id: 83332:Rv2828A
uniprot id: I6YAC9
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3736
gene id: 83332:Rv3736
uniprot id: O69703
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH araC/xylS-type

83332:Rv0968
gene id: 83332:Rv0968
uniprot id: P9WKL9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0968
up seq anno feature ids: PRO_0000103765

83332:Rv1460
gene id: 83332:Rv1460
uniprot id: O53151
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3561
gene id: 83332:Rv3561
uniprot id: P96843
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase
up seq anno feature ids: PRO_0000430639

83332:Rv1288
gene id: 83332:Rv1288
uniprot id: P9WM39
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: 85% reduction of activity.
up seq anno comments: Complete loss of activity.
up seq anno comments: Esterase Rv1288
up seq anno comments: LysM 1
up seq anno comments: LysM 2
up seq anno comments: LysM 3
up seq anno feature ids: PRO_0000103786

83332:Rv0753c
gene id: 83332:Rv0753c
uniprot id: O53816
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Aldehyde dehydrogenase
up seq anno comments: Disordered

83332:Rv2939
gene id: 83332:Rv2939
uniprot id: P9WIN5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-fold decrease in affinity for acylated mas protein. No change in catalytic activity.
up seq anno comments: 40-fold decrease in affinity for acylated mas protein. No change in catalytic activity.
up seq anno comments: 65-fold decrease in activity.
up seq anno comments: 76-fold decrease in activity.
up seq anno comments: About 2-fold decrease in activity.
up seq anno comments: Important for mas ACP domain recognition
up seq anno comments: Less than 1.9-fold decrease in activity.
up seq anno comments: N-acetylmethionine
up seq anno comments: Phosphothreonine
up seq anno comments: Phthiocerol/phthiodiolone dimycocerosyl transferase
up seq anno comments: Proton acceptor
up seq anno comments: Structural role in the organization of the active site
up seq anno feature ids: PRO_0000058229

83332:Rv0188
gene id: 83332:Rv0188
uniprot id: O07432
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1408
gene id: 83332:Rv1408
uniprot id: P9WI51
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Ribulose-phosphate 3-epimerase
up seq anno feature ids: PRO_0000171578

83332:Rv3631
gene id: 83332:Rv3631
uniprot id: O06376
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Glycosyltransferase 2-like

83332:Rv2585c
gene id: 83332:Rv2585c
uniprot id: P9WL77
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: Uncharacterized lipoprotein Rv2585c
up seq anno feature ids: PRO_0000014137

83332:Rv2943
gene id: 83332:Rv2943
uniprot id: I6X5T4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Integrase catalytic

83332:Rv2465c
gene id: 83332:Rv2465c
uniprot id: P9WKD7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Ribose-5-phosphate isomerase B
up seq anno feature ids: PRO_0000251148

83332:Rv2910c
gene id: 83332:Rv2910c
uniprot id: P9WL25
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2910c
up seq anno feature ids: PRO_0000104098

83332:Rv3444c
gene id: 83332:Rv3444c
uniprot id: I6YC53
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxT
up seq anno feature ids: PRO_0000436933

83332:Rv3738c
gene id: 83332:Rv3738c
uniprot id: P9WHX1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized PPE family protein PPE66
up seq anno feature ids: PRO_0000379592

83332:Rv2344c
gene id: 83332:Rv2344c
uniprot id: P9WNY7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Deoxyguanosinetriphosphate triphosphohydrolase-like protein
up seq anno comments: Disordered
up seq anno comments: HD
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000205310

83332:Rv2127
gene id: 83332:Rv2127
uniprot id: P9WQM9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: L-asparagine permease 1
up seq anno feature ids: PRO_0000054189

83332:Rv3749c
gene id: 83332:Rv3749c
uniprot id: L0TGF0
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative ribonuclease VapC50
up seq anno feature ids: PRO_0000433057

83332:Rv0132c
gene id: 83332:Rv0132c
uniprot id: P96809
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: F420-dependent hydroxymycolic acid dehydrogenase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000435125

83332:Rv0981
gene id: 83332:Rv0981
uniprot id: P9WGM9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Abolishes phosphorylation. No loss of DNA-binding activity in vitro.
up seq anno comments: No loss of phosphorylation.
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Response regulator MprA
up seq anno comments: Response regulatory
up seq anno feature ids: PRO_0000308427

83332:Rv1316c
gene id: 83332:Rv1316c
uniprot id: P9WJW5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Methylated-DNA--protein-cysteine methyltransferase
up seq anno comments: Nucleophile; methyl group acceptor
up seq anno feature ids: PRO_0000139369

83332:Rv0450c
gene id: 83332:Rv0450c
uniprot id: P9WJV3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Siderophore exporter MmpL4
up seq anno feature ids: PRO_0000103566

83332:Rv1816
gene id: 83332:Rv1816
uniprot id: P9WMC9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional regulator Rv1816
up seq anno feature ids: PRO_0000070666

83332:Rv3572
gene id: 83332:Rv3572
uniprot id: I6X7P2
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Secreted protein
up seq anno feature ids: PRO_5038520580

83332:Rv0803
gene id: 83332:Rv0803
uniprot id: P9WHL7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: Phosphoribosylformylglycinamidine synthase subunit PurL
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000100473

83332:Rv0273c
gene id: 83332:Rv0273c
uniprot id: O86342
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1988
gene id: 83332:Rv1988
uniprot id: Q10838
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Ribosomal RNA adenine methylase transferase N-terminal

83332:Rv0766c
gene id: 83332:Rv0766c
uniprot id: P9WPP5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 123
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052276

83332:Rv1629
gene id: 83332:Rv1629
uniprot id: P9WNU5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 3'-5' exonuclease
up seq anno comments: 5'-3' exonuclease
up seq anno comments: DNA polymerase I
up seq anno feature ids: PRO_0000101247

83332:Rv1953
gene id: 83332:Rv1953
uniprot id: P9WF99
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC14
up seq anno feature ids: PRO_0000407874

83332:Rv2469c
gene id: 83332:Rv2469c
uniprot id: O53196
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HNH nuclease

83332:Rv3322c
gene id: 83332:Rv3322c
uniprot id: L7N687
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv1771
gene id: 83332:Rv1771
uniprot id: P9WIT3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type
up seq anno comments: L-gulono-1,4-lactone dehydrogenase
up seq anno feature ids: PRO_0000420410

83332:Rv2288
gene id: 83332:Rv2288
uniprot id: P9WLE5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2288
up seq anno feature ids: PRO_0000104007

83332:Rv2607
gene id: 83332:Rv2607
uniprot id: P9WIJ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Pyridoxine 5'-phosphate oxidase
up seq anno feature ids: PRO_0000167723

83332:Rv3480c
gene id: 83332:Rv3480c
uniprot id: P9WKA7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv3480c
up seq anno feature ids: PRO_0000222920

83332:Rv0400c
gene id: 83332:Rv0400c
uniprot id: P95208
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv2953
gene id: 83332:Rv2953
uniprot id: P9WGV5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Trans-acting enoyl reductase
up seq anno feature ids: PRO_0000304694

83332:Rv2438c
gene id: 83332:Rv2438c
uniprot id: P9WJJ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: CN hydrolase
up seq anno comments: Causes a decrease in ammonia channel efficiency to 70% compared with wild-type enzyme.
up seq anno comments: Disordered
up seq anno comments: For glutaminase activity
up seq anno comments: Glutamine-dependent NAD(+) synthetase
up seq anno comments: Lack of glutamine-dependent activity. Retains 30% of ammonia-dependent activity.
up seq anno comments: Lack of glutamine-dependent activity. Retains 90% of ammonia-dependent activity.
up seq anno comments: Lack of glutamine-dependent and ammonia-dependent activities.
up seq anno comments: Ligase
up seq anno comments: Nucleophile; for glutaminase activity
up seq anno comments: Proton acceptor; for glutaminase activity
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000152241

83332:Rv3800c
gene id: 83332:Rv3800c
uniprot id: I6X8D2
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-ester intermediate; for acyltransferase activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase activity
up seq anno comments: Acyltransferase
up seq anno comments: Cannot form alpha-alkyl beta-ketoacids derivatives.
up seq anno comments: Carrier 1
up seq anno comments: Carrier 2
up seq anno comments: Confers thiophene resistance.
up seq anno comments: Coumestan resistant.
up seq anno comments: Disordered
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: For thioesterase-like activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: Polyketide synthase Pks13
up seq anno comments: Thioesterase-like
up seq anno feature ids: PRO_0000451588

83332:Rv1901
gene id: 83332:Rv1901
uniprot id: P9WPE3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: CinA-like protein
up seq anno feature ids: PRO_0000156770

83332:Rv1327c
gene id: 83332:Rv1327c
uniprot id: P9WQ17
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
up seq anno comments: Disordered
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000054347

83332:Rv0799c
gene id: 83332:Rv0799c
uniprot id: I6Y4U9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Dye-decolorizing peroxidase
up seq anno comments: Protein no longer targeted to encapsulin nanocompartments, retains enzyme activity.
up seq anno comments: Proton acceptor
up seq anno comments: Targeting peptide
up seq anno comments: proximal binding residue
up seq anno feature ids: PRO_0000455327

83332:Rv2554c
gene id: 83332:Rv2554c
uniprot id: P9WGV7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Putative pre-16S rRNA nuclease
up seq anno feature ids: PRO_0000172100

83332:Rv0626
gene id: 83332:Rv0626
uniprot id: P9WF19
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: Putative antitoxin VapB5
up seq anno feature ids: PRO_0000408046

83332:Rv0346c
gene id: 83332:Rv0346c
uniprot id: P9WQM7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: L-asparagine permease 2
up seq anno feature ids: PRO_0000054190

83332:Rv1472
gene id: 83332:Rv1472
uniprot id: P9WNN7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable enoyl-CoA hydratase EchA12
up seq anno feature ids: PRO_0000109341

83332:Rv3220c
gene id: 83332:Rv3220c
uniprot id: P9WGL5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: GAF
up seq anno comments: Histidine kinase
up seq anno comments: Loss of activity, cannot rescue a deletion mutant.
up seq anno comments: PAS-like
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Resistant to NO inhibition.
up seq anno comments: Resistant to copper and NO inhibition.
up seq anno comments: Sensor histidine kinase PdtaS
up seq anno feature ids: PRO_0000386596

83332:Rv1298
gene id: 83332:Rv1298
uniprot id: P9WHA1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL31
up seq anno feature ids: PRO_0000173132

83332:Rv2132
gene id: 83332:Rv2132
uniprot id: O06243
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Ribbon-helix-helix protein CopG

83332:Rv0124
gene id: 83332:Rv0124
uniprot id: Q79G08
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv3490
gene id: 83332:Rv3490
uniprot id: P9WN11
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Involved in alpha anomer selectivity
up seq anno comments: Trehalose-6-phosphate synthase
up seq anno feature ids: PRO_0000348922

83332:Rv0198c
gene id: 83332:Rv0198c
uniprot id: I6X8R2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Peptidase M13 C-terminal
up seq anno comments: Peptidase M13 N-terminal

83332:Rv1590
gene id: 83332:Rv1590
uniprot id: P9WLT7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1590
up seq anno feature ids: PRO_0000103888

83332:Rv1957
gene id: 83332:Rv1957
uniprot id: P95257
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: SecB-like chaperone Rv1957
up seq anno feature ids: PRO_0000407372

83332:Rv3127
gene id: 83332:Rv3127
uniprot id: P9WL07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv3127
up seq anno feature ids: PRO_0000392938

83332:Rv2781c
gene id: 83332:Rv2781c
uniprot id: I6X5C5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nitronate monooxygenase

83332:Rv1418
gene id: 83332:Rv1418
uniprot id: P9WK43
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LprH
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018148

83332:Rv3643
gene id: 83332:Rv3643
uniprot id: O06364
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2601A
gene id: 83332:Rv2601A
uniprot id: P9WJ21
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB41
up seq anno feature ids: PRO_0000408082

83332:Rv2245
gene id: 83332:Rv2245
uniprot id: P9WQD9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-oxoacyl-[acyl-carrier-protein] synthase 1
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Increases resistance to isoniazid.
up seq anno comments: Interacts with the inhibitor thiolactomycin
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Loss of activity with hexadecanoyl-CoA.
up seq anno comments: Mimics structural changes caused by acyl-enzyme formation.
up seq anno feature ids: PRO_0000180333

83332:Rv3456c
gene id: 83332:Rv3456c
uniprot id: P9WHD3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL17
up seq anno feature ids: PRO_0000175536

83332:Rv0322
gene id: 83332:Rv0322
uniprot id: O07248
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Nucleophile
up seq anno comments: UDP-glucose/GDP-mannose dehydrogenase C-terminal

83332:Rv3872
gene id: 83332:Rv3872
uniprot id: P9WIG7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE family immunomodulator PE35
up seq anno feature ids: PRO_0000394202

83332:Rv2073c
gene id: 83332:Rv2073c
uniprot id: P9WGR3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv2073c
up seq anno feature ids: PRO_0000054864

83332:Rv3252c
gene id: 83332:Rv3252c
uniprot id: O05895
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Fatty acid desaturase
up seq anno comments: Helical

83332:Rv2359
gene id: 83332:Rv2359
uniprot id: P9WN85
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Zinc uptake regulation protein
up seq anno feature ids: PRO_0000419204

83332:Rv2331A
gene id: 83332:Rv2331A
uniprot id: Q79FF7
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3760
gene id: 83332:Rv3760
uniprot id: O69726
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized membrane protein Rv3760
up seq anno feature ids: PRO_0000415510

83332:Rv0991c
gene id: 83332:Rv0991c
uniprot id: O05574
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Putative regulatory protein FmdB Zinc ribbon

83332:Rv0462
gene id: 83332:Rv0462
uniprot id: P9WHH9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Dihydrolipoyl dehydrogenase
up seq anno comments: Proton acceptor
up seq anno comments: Redox-active
up seq anno comments: Reduces lipoamide dehydrogenase activity by 82%.
up seq anno comments: Reduces lipoamide dehydrogenase activity by 89%.
up seq anno comments: Reduces lipoamide dehydrogenase activity by 91%.
up seq anno comments: Reduces lipoamide dehydrogenase activity by 94%.
up seq anno comments: Reduces lipoamide dehydrogenase activity by 95%.
up seq anno comments: Reduces lipoamide dehydrogenase activity by 96%.
up seq anno feature ids: PRO_0000068034

83332:Rv3069
gene id: 83332:Rv3069
uniprot id: P9WP63
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Fluoride-specific ion channel FluC 1
up seq anno comments: Helical
up seq anno feature ids: PRO_0000110137

83332:Rv0636
gene id: 83332:Rv0636
uniprot id: I6WYY7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MaoC-like

83332:Rv3584
gene id: 83332:Rv3584
uniprot id: P9WK63
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LpqE
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018124

83332:Rv0289
gene id: 83332:Rv0289
uniprot id: P9WJC7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ESX-3 secretion-associated protein EspG3
up seq anno feature ids: PRO_0000394154

83332:Rv0814c
gene id: 83332:Rv0814c
uniprot id: P0CG95
uniprot id: P0CG96
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Uncharacterized protein Rv0814c
up seq anno comments: Uncharacterized protein Rv3118
up seq anno feature ids: PRO_0000396084
up seq anno feature ids: PRO_0000396092

83332:Rv1639c
gene id: 83332:Rv1639c
uniprot id: P94973
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2481c
gene id: 83332:Rv2481c
uniprot id: O53206
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3395A
gene id: 83332:Rv3395A
uniprot id: Q6MWX4
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010295883

83332:Rv2063A
gene id: 83332:Rv2063A
uniprot id: P0CL62
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Disordered
up seq anno comments: Probable endoribonuclease MazF7
up seq anno feature ids: PRO_0000406308

83332:Rv1122
gene id: 83332:Rv1122
uniprot id: O06574
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 6-phosphogluconate dehydrogenase C-terminal

83332:Rv2655c
gene id: 83332:Rv2655c
uniprot id: I6Y1F0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DUF3631
up seq anno comments: Disordered

83332:Rv1439c
gene id: 83332:Rv1439c
uniprot id: O06820
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv2298
gene id: 83332:Rv2298
uniprot id: P9WQA7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton donor
up seq anno comments: Uncharacterized oxidoreductase Rv2298
up seq anno feature ids: PRO_0000070396

83332:Rv0938
gene id: 83332:Rv0938
uniprot id: P9WNV3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 20% ligase activity for singly nicked dsDNA, normal N6-AMP-lysine intermediate formed, no effect on phosphodiester bond formation, no effect on DNA polymerase.
up seq anno comments: 3-phosphoesterase domain (PE)
up seq anno comments: Basic and acidic residues
up seq anno comments: Better than wild-type DNA-binding and filling on single nt gaps, impaired gap filling on more complicated templates (in Pol domain).
up seq anno comments: Binds DNA, no formation of DNA end-bridging complex, no polymerase activity. Significantly decreased ability to fill in 2 nt gaps (in Pol domain).
up seq anno comments: Binds DNA, no gap-filling (in Pol domain).
up seq anno comments: DNA repair polymerase domain (Pol); interacts with Ku
up seq anno comments: Disordered
up seq anno comments: Interaction with target DNA
up seq anno comments: Ligase domain (Lig)
up seq anno comments: Loss of DNA-binding, no polymerase activity, no effect of gap-filling (in Pol domain).
up seq anno comments: Loss of adenyltransferase activity, no N6-AMP-lysine formation and loss of ligase activity. No effect on phosphodiester bond formation on pre-adenylated nicked DNA, or on DNA polymerase.
up seq anno comments: Loss of exonuclease, no DNA repair.
up seq anno comments: Loss of polymerase activities, no DNA repair (in Pol domain).
up seq anno comments: Multifunctional non-homologous end joining DNA repair protein LigD
up seq anno comments: N6-AMP-lysine intermediate; for ligase activity
up seq anno comments: No ligase of singly nicked dsDNA activity, 25% N6-AMP-lysine intermediate formed, decreased phosphodiester bond formation, no effect on DNA polymerase.
up seq anno comments: No ligase of singly nicked dsDNA activity, no N6-AMP-lysine intermediate formed, decreased phosphodiester bond formation on pre-adenylated nicked DNA, no effect on DNA polymerase.
up seq anno comments: No ligase of singly nicked dsDNA activity, no N6-AMP-lysine intermediate formed, no phosphodiester bond formation on pre-adenylated nicked DNA, no effect on DNA polymerase.
up seq anno comments: Not required for ligase activity
up seq anno comments: On substrate with 5'-phosphate, 1 base pair (bp) complementarity and 1 nucleotide (nt) gap, greatly reduced DNA-binding and gap-filling. Barely detectable activity on substrate with high complementarity and 3'-overhang (in Pol domain).
up seq anno comments: On substrate with 5'-phosphate, 1 bp complementarity and 1 nt gap, greatly reduced DNA-binding and gap-filling. Barely detectable activity on substrate with high complementarity and 3'-overhang (in Pol domain).
up seq anno comments: On substrate with 5'-phosphate, 1 bp complementarity and 1 nt gap, greatly reduced DNA-binding and gap-filling. No activity on substrate with high complementarity and 3'-overhang (in Pol domain).
up seq anno comments: Transition state stabilizer; for 3'-phosphoesterase activity
up seq anno comments: Wild-type filling on single nt gaps, impaired gap filling on more complicated templates (in Pol domain).
up seq anno feature ids: PRO_0000059627

83332:Rv3141
gene id: 83332:Rv3141
uniprot id: P95185
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Enoyl reductase (ER)

83332:Rv0410c
gene id: 83332:Rv0410c
uniprot id: P9WI73
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decrease in activity.
up seq anno comments: Decrease in activity; when associated with A-106; A-109 and A-128.
up seq anno comments: Decrease in activity; when associated with A-106; A-109 and A-131.
up seq anno comments: Decrease in activity; when associated with A-106; A-128 and A-131.
up seq anno comments: Decrease in activity; when associated with A-109; A-128 and A-131.
up seq anno comments: Decreases inhibition by AX20017; when associated with S-87.
up seq anno comments: Decreases inhibition by AX20017; when associated with S-92.
up seq anno comments: Disordered
up seq anno comments: Lack of activity.
up seq anno comments: Lack of activity; when associated with S-106; S-109 and S-128.
up seq anno comments: Lack of activity; when associated with S-106; S-109 and S-131.
up seq anno comments: Lack of activity; when associated with S-106; S-128 and S-131.
up seq anno comments: Lack of activity; when associated with S-109; S-128 and S-131.
up seq anno comments: Lack of phosphorylation. Does not affect kinase activity.
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Polar residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknG
up seq anno comments: TPR
up seq anno feature ids: PRO_0000171216

83332:Rv2620c
gene id: 83332:Rv2620c
uniprot id: I6Y9U6
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2118c
gene id: 83332:Rv2118c
uniprot id: P9WFZ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: tRNA (adenine(58)-N(1))-methyltransferase TrmI
up seq anno feature ids: PRO_0000407309

83332:Rv2963
gene id: 83332:Rv2963
uniprot id: I6YET7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative permease Rv2963
up seq anno feature ids: PRO_0000433101

83332:Rv2448c
gene id: 83332:Rv2448c
uniprot id: P9WFS9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Initiator Methionine
up seq anno labels: Motif
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Removed
up seq anno comments: Valine--tRNA ligase
up seq anno feature ids: PRO_0000106232

83332:Rv1084
gene id: 83332:Rv1084
uniprot id: O53432
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF255

83332:Rv3262
gene id: 83332:Rv3262
uniprot id: P9WP79
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Bifunctional F420 biosynthesis protein FbiB
up seq anno comments: Coenzyme F420:L-glutamate ligase
up seq anno comments: Dehydro-coenzyme F420-0 reductase
up seq anno feature ids: PRO_0000145780

83332:Rv0509
gene id: 83332:Rv0509
uniprot id: P9WMP7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Disordered
up seq anno comments: Glutamyl-tRNA reductase
up seq anno comments: Important for activity
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000114042

83332:Rv1337
gene id: 83332:Rv1337
uniprot id: E2IBS4
uniprot id: P9WM21
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Peptidase S54 rhomboid
up seq anno comments: Uncharacterized protein Rv1337
up seq anno feature ids: PRO_0000103811

83332:Rv0475
gene id: 83332:Rv0475
uniprot id: P9WIP9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Heparin-binding hemagglutinin
up seq anno feature ids: PRO_0000083910

83332:Rv2566
gene id: 83332:Rv2566
uniprot id: Q50732
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transglutaminase-like

83332:Rv3080c
gene id: 83332:Rv3080c
uniprot id: P9WI65
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Loss of activity.
up seq anno comments: Loss of activity; when associated with A-179.
up seq anno comments: Loss of activity; when associated with A-181.
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknK
up seq anno feature ids: PRO_0000171224

83332:Rv0301
gene id: 83332:Rv0301
uniprot id: P9WFB9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC2
up seq anno feature ids: PRO_0000407865

83332:Rv0467
gene id: 83332:Rv0467
uniprot id: P9WKK7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adopts a conformation almost identical to the wild-type.
up seq anno comments: Isocitrate lyase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000068779

83332:Rv1483
gene id: 83332:Rv1483
uniprot id: P9WGT3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-oxoacyl-[acyl-carrier-protein] reductase MabA
up seq anno comments: 70% decrease in activity with acetoacetyl-CoA as substrate. Does not affect NADP binding.
up seq anno comments: Complete protein inactivation and freezes the catalytic site into its closed form. Totally inactive; when associated with V-60 and L-144.
up seq anno comments: Displays a lower activity than the wild-type and a slightly decreased affinity for the cofactor. Retains 84% of activity; when associated with L-144. Totally inactive; when associated with A-139 and L-144.
up seq anno comments: Important for activity
up seq anno comments: Loss of activity. Can still bind NADPH.
up seq anno comments: Loss of activity. Impaired NADPH binding.
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphomimetic mutant that retains less than 10% of wild-type reductase activity. Impaired NADPH binding. Overproduction of the mutant leads to a significant inhibition of de novo biosynthesis of mycolic acids.
up seq anno comments: Phosphothreonine
up seq anno comments: Proton acceptor
up seq anno comments: Recombinant protein expressed in E.coli.
up seq anno comments: Removed
up seq anno comments: Retains 22% of wild-type reductase activity. Strong decrease in phosphorylation by PknB. Lack of phosphorylation by PknB; when associated with A-21 and A-114.
up seq anno comments: Slight decrease in phosphorylation by PknB. Lack of phosphorylation by PknB; when associated with A-114 and A-191.
up seq anno comments: Slight decrease in phosphorylation by PknB. Lack of phosphorylation by PknB; when associated with A-21 and A-191.
up seq anno comments: Stabilizes the catalytic loop in its open active form. Retains 84% of activity; when associated with V-60. Totally inactive; when associated with V-60 and A-139.
up seq anno feature ids: PRO_0000054677

83332:Rv1998c
gene id: 83332:Rv1998c
uniprot id: P9WLN9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1998c
up seq anno feature ids: PRO_0000103926

83332:Rv0101
gene id: 83332:Rv0101
uniprot id: Q10896
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: Carrier 1
up seq anno comments: Carrier 2
up seq anno comments: Isonitrile lipopeptide synthase
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: Thioester reductase (TE)
up seq anno feature ids: PRO_0000458122

83332:Rv1308
gene id: 83332:Rv1308
uniprot id: P9WPU7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Site
up seq anno comments: ATP synthase subunit alpha
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Required for activity
up seq anno feature ids: PRO_0000144339

83332:Rv2143
gene id: 83332:Rv2143
uniprot id: O06232
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Phosphoribosyltransferase

83332:Rv0236A
gene id: 83332:Rv0236A
uniprot id: P9WLB1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Putative secreted protein Rv0236.1
up seq anno feature ids: PRO_0000014068

83332:Rv0771
gene id: 83332:Rv0771
uniprot id: I6Y4S7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxymuconolactone decarboxylase-like

83332:Rv0420c
gene id: 83332:Rv0420c
uniprot id: P96266
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3501c
gene id: 83332:Rv3501c
uniprot id: O53546
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1601
gene id: 83332:Rv1601
uniprot id: P9WML9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Imidazoleglycerol-phosphate dehydratase
up seq anno feature ids: PRO_0000158146
up seq anno feature ids: PRO_0000445482

83332:Rv1968
gene id: 83332:Rv1968
uniprot id: O53969
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv2458
gene id: 83332:Rv2458
uniprot id: O53185
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Hcy-binding

83332:Rv1428c
gene id: 83332:Rv1428c
uniprot id: O06830
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv2691
gene id: 83332:Rv2691
uniprot id: I6XF25
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: RCK C-terminal
up seq anno comments: RCK N-terminal

83332:Rv3466
gene id: 83332:Rv3466
uniprot id: P9WKY1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv3466
up seq anno feature ids: PRO_0000104137

83332:Rv0332
gene id: 83332:Rv0332
uniprot id: O07256
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MDMPI C-terminal
up seq anno comments: Mycothiol-dependent maleylpyruvate isomerase metal-binding

83332:Rv2083
gene id: 83332:Rv2083
uniprot id: P9WLK3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized protein Rv2083
up seq anno feature ids: PRO_0000103954

83332:Rv2926c
gene id: 83332:Rv2926c
uniprot id: P9WL17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2926c
up seq anno feature ids: PRO_0000104106

83332:Rv3806c
gene id: 83332:Rv3806c
uniprot id: P9WFR5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Decaprenyl-phosphate phosphoribosyltransferase
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: No DPPR synthase activity and the protein is not expressed in the membrane.
up seq anno comments: No DPPR synthase activity.
up seq anno comments: Only small effects on the DPPR synthase activity.
up seq anno comments: Slight DPPR synthase activity.
up seq anno comments: Substantially reduced the DPPR synthase activity.
up seq anno comments: The DPPR synthase activity is strongly diminished.
up seq anno feature ids: PRO_0000420587

83332:Rv0154c
gene id: 83332:Rv0154c
uniprot id: P96831
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable acyl-CoA dehydrogenase FadE2
up seq anno feature ids: PRO_0000455761

83332:Rv3770c
gene id: 83332:Rv3770c
uniprot id: P72037
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1003
gene id: 83332:Rv1003
uniprot id: P9WGW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Ribosomal RNA small subunit methyltransferase I
up seq anno feature ids: PRO_0000211946

83332:Rv2753c
gene id: 83332:Rv2753c
uniprot id: P9WP25
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-hydroxy-tetrahydrodipicolinate synthase
up seq anno comments: Exists as dimer in solution. Has similar activity to the wild-type enzyme. Slight decrease in affinity for substrates.
up seq anno comments: Part of a proton relay during catalysis
up seq anno comments: Proton donor/acceptor
up seq anno comments: Schiff-base intermediate with substrate
up seq anno feature ids: PRO_0000103128

83332:Rv3597c
gene id: 83332:Rv3597c
uniprot id: P9WIP7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Loss of DNA-binding, in fragment 66-112.
up seq anno comments: Loss of activity.
up seq anno comments: Loss of activity. Can form dimers but does not bind DNA.
up seq anno comments: No change in activity. Can still bind DNA and form dimers.
up seq anno comments: Nucleoid-associated protein Lsr2
up seq anno comments: Reduced DNA-binding, in fragment 66-112.
up seq anno feature ids: PRO_0000021625

83332:Rv0825c
gene id: 83332:Rv0825c
uniprot id: O53836
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1656
gene id: 83332:Rv1656
uniprot id: P9WIT9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Ornithine carbamoyltransferase
up seq anno feature ids: PRO_0000112955

83332:Rv2493
gene id: 83332:Rv2493
uniprot id: P9WJ25
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB38
up seq anno feature ids: PRO_0000408080

83332:Rv3508
gene id: 83332:Rv3508
uniprot id: O53553
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS54
up seq anno feature ids: PRO_0000023578

83332:Rv2386a
gene id: 83332:Rv2386a
uniprot id: I6YD99
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2386A/RVBD_2386A
up seq anno feature ids: PRO_0000431253

83332:Rv0285
gene id: 83332:Rv0285
uniprot id: L7N695
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: PE
up seq anno comments: PE family immunomodulator PE5
up seq anno feature ids: PRO_5007687871

83332:Rv1132
gene id: 83332:Rv1132
uniprot id: O06583
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1487
gene id: 83332:Rv1487
uniprot id: P71767
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NfeD-like C-terminal

83332:Rv1451
gene id: 83332:Rv1451
uniprot id: P9WFR7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Protoheme IX farnesyltransferase
up seq anno feature ids: PRO_0000327090

83332:Rv2310
gene id: 83332:Rv2310
uniprot id: P9WLC3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2310
up seq anno feature ids: PRO_0000104018

83332:Rv3152
gene id: 83332:Rv3152
uniprot id: P9WIX1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: NADH-quinone oxidoreductase subunit H
up seq anno feature ids: PRO_0000117529

83332:Rv0950c
gene id: 83332:Rv0950c
uniprot id: P71560
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Peptidase M23

83332:Rv1776c
gene id: 83332:Rv1776c
uniprot id: O33179
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv2973c
gene id: 83332:Rv2973c
uniprot id: P9WMQ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: ATP-dependent DNA helicase RecG
up seq anno comments: DEQH box
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno feature ids: PRO_0000102146

83332:Rv1100
gene id: 83332:Rv1100
uniprot id: O53448
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2786c
gene id: 83332:Rv2786c
uniprot id: I6X5C9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Riboflavin kinase

83332:Rv3274c
gene id: 83332:Rv3274c
uniprot id: P9WQG1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable acyl-CoA dehydrogenase FadE25
up seq anno feature ids: PRO_0000201188

83332:Rv3661
gene id: 83332:Rv3661
uniprot id: P9WGJ1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Nucleophile
up seq anno comments: Polar residues
up seq anno comments: Probable phosphatase Rv3661
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000156895

83332:Rv1740
gene id: 83332:Rv1740
uniprot id: P9WJ31
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB34
up seq anno feature ids: PRO_0000413610

83332:Rv0170
gene id: 83332:Rv0170
uniprot id: O07414
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv1348
gene id: 83332:Rv1348
uniprot id: P9WQJ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Cytoplasmic
up seq anno comments: Decrease in FAD-binding and loss of activity.
up seq anno comments: Disordered
up seq anno comments: FAD-binding FR-type
up seq anno comments: Helical
up seq anno comments: Mycobactin import ATP-binding/permease protein IrtA
up seq anno comments: No change in FAD-binding and in activity.
up seq anno comments: Periplasmic
up seq anno feature ids: PRO_0000093255

83332:Rv3090
gene id: 83332:Rv3090
uniprot id: O05769
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Protease Rv3090
up seq anno feature ids: PRO_0000458112

83332:Rv2576c
gene id: 83332:Rv2576c
uniprot id: P9WL83
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2576c
up seq anno feature ids: PRO_0000104058

83332:Rv0527
gene id: 83332:Rv0527
uniprot id: L7N671
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Cytochrome C biogenesis protein transmembrane
up seq anno comments: Helical

83332:Rv3244c
gene id: 83332:Rv3244c
uniprot id: P9WK37
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: Lipoprotein LpqB
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000286724

83332:Rv2009
gene id: 83332:Rv2009
uniprot id: P9WLM7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Turn
up seq anno comments: Antitoxin VapB15
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000103938

83332:Rv0642c
gene id: 83332:Rv0642c
uniprot id: Q79FX8
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Hydroxymycolate synthase MmaA4
up seq anno feature ids: PRO_0000398365

83332:Rv0113
gene id: 83332:Rv0113
uniprot id: P9WGG1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: 14.5-fold decrease in catalytic efficiency.
up seq anno comments: 24-fold decrease in catalytic efficiency.
up seq anno comments: 3.1-fold decrease in catalytic efficiency.
up seq anno comments: 3.5-fold decrease in catalytic efficiency.
up seq anno comments: 4.4-fold decrease in catalytic efficiency.
up seq anno comments: 6.6-fold decrease in catalytic efficiency.
up seq anno comments: Phosphoheptose isomerase
up seq anno comments: SIS
up seq anno feature ids: PRO_0000136536

83332:Rv0970
gene id: 83332:Rv0970
uniprot id: P9WKL7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0970
up seq anno feature ids: PRO_0000103767

83332:Rv2678c
gene id: 83332:Rv2678c
uniprot id: P9WFE1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Transition state stabilizer
up seq anno comments: Uroporphyrinogen decarboxylase
up seq anno feature ids: PRO_0000187616

83332:Rv2153c
gene id: 83332:Rv2153c
uniprot id: P9WJK9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
up seq anno feature ids: PRO_0000109189

83332:Rv1644
gene id: 83332:Rv1644
uniprot id: P94978
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: RNA 2-O ribose methyltransferase substrate binding

83332:Rv3914
gene id: 83332:Rv3914
uniprot id: P9WG67
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Redox-active
up seq anno comments: Removed
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_0000120117

83332:Rv0783c
gene id: 83332:Rv0783c
uniprot id: P9WG89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Multidrug resistance protein B homolog
up seq anno feature ids: PRO_0000390687

83332:Rv1611
gene id: 83332:Rv1611
uniprot id: P9WFX7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Indole-3-glycerol phosphate synthase
up seq anno feature ids: PRO_0000154234

83332:Rv1978
gene id: 83332:Rv1978
uniprot id: O53979
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv2268c
gene id: 83332:Rv2268c
uniprot id: P9WPN7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Beta-dihydromenaquinone-9 omega-hydroxylase
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052284

83332:Rv0006
gene id: 83332:Rv0006
uniprot id: P9WG47
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 17-fold increased resistance to fluoroquinolones, 4- to 8-fold reduction in fluoroquinolone-induced DNA cleavage.
up seq anno comments: 25- 45-fold increased resistance to fluoroquinolones, 4- to 8-fold reduction in fluoroquinolone-induced DNA cleavage. Supercoiling, relaxation, decatenation activities no longer inhibited by MfpA.
up seq anno comments: 4- to 16-fold more efficient in fluoroquinolone-induced DNA cleavage alone. Hypersusceptibile, 2- to 14-fold higher sensitivity to fluoroquinolones, 2- to 8-fold more efficient in fluoroquinolone-induced DNA cleavage; when associated with A-80.
up seq anno comments: 80-fold increased resistance to fluoroquinolones, 32- to 64-fold reduction in fluoroquinolone-induced DNA cleavage.
up seq anno comments: C-terminal domain CTD
up seq anno comments: Confers ciprofloxacin resistance, in clinical isolate.
up seq anno comments: Confers fluoroquinolone resistance, IC(50) is 2- to 26-fold higher than wild-type.
up seq anno comments: Confers fluoroquinolone resistance, IC(50) is 3- to 43-fold higher than wild-type, in strains H37Ra and H37Rv.
up seq anno comments: Confers ofloxacin resistance.
up seq anno comments: DNA gyrase subunit A
up seq anno comments: EF-hand
up seq anno comments: GyrA-box
up seq anno comments: GyrA-box-1
up seq anno comments: Increased susceptibility to fluoroquinolones (makes sequence more like E.coli), supercoiling, relaxation, decatenation activities still inhibited by MfpA.
up seq anno comments: N-acetylthreonine
up seq anno comments: No change in supercoiling activity, wild-type decatenation or fluoroquinolone-induced DNA cleavage.
up seq anno comments: No supercoiling activity, almost wild-type decatenation activity, wild-type fluoroquinolone-induced DNA cleavage.
up seq anno comments: No supercoiling activity, wild-type decatenation and fluoroquinolone-induced DNA cleavage.
up seq anno comments: No supercoiling or decatenation activity, decreased fluoroquinolone-induced DNA cleavage.
up seq anno comments: O-(5'-phospho-DNA)-tyrosine intermediate
up seq anno comments: Reduced supercoiling activity, wild-type decatenation and fluoroquinolone-induced DNA cleavage.
up seq anno comments: Removed
up seq anno comments: Significant reduction in DNA wrapping and supercoiling activity, no change in decatanation or relaxation activities.
up seq anno comments: Slight reduction in supercoiling activity.
up seq anno comments: Slight resistance to fluoroquinolones. Hypersusceptibile, 2- to 14-fold higher sensitivity to fluoroquinolones, 2- to 8-fold more efficient in fluoroquinolone-induced DNA cleavage; when associated with G-90.
up seq anno comments: Wild-type decatenase activity (changes residue to match E.coli).
up seq anno comments: Wild-type decatenase activity (changes residues to match E.coli).
up seq anno comments: Wild-type supercoiling, decatenation and fluoroquinolone-induced DNA cleavage.
up seq anno feature ids: PRO_0000145243

83332:Rv0343
gene id: 83332:Rv0343
uniprot id: P9WJ95
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Isoniazid-induced protein IniC
up seq anno feature ids: PRO_0000390793

83332:Rv2624c
gene id: 83332:Rv2624c
uniprot id: P9WFD5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Universal stress protein Rv2624c
up seq anno feature ids: PRO_0000392629

83332:Rv2094c
gene id: 83332:Rv2094c
uniprot id: P9WGA1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Sec-independent protein translocase protein TatA
up seq anno feature ids: PRO_0000097945

83332:Rv2936
gene id: 83332:Rv2936
uniprot id: P9WQL9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Doxorubicin resistance ATP-binding protein DrrA
up seq anno feature ids: PRO_0000393225

83332:Rv3818
gene id: 83332:Rv3818
uniprot id: P9WH21
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Putative Rieske 2Fe-2S iron-sulfur protein Rv3818
up seq anno comments: Rieske
up seq anno feature ids: PRO_0000396106

83332:Rv2587c
gene id: 83332:Rv2587c
uniprot id: P9WGP1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Protein translocase subunit SecD
up seq anno feature ids: PRO_0000095966

83332:Rv3780
gene id: 83332:Rv3780
uniprot id: P9WKX3
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Bacterial proteasome activator
up seq anno comments: Disordered
up seq anno comments: HbYX motif
up seq anno comments: Loss of interaction with the proteasome subunit PrcA.
up seq anno feature ids: PRO_0000104145

83332:Rv1013
gene id: 83332:Rv1013
uniprot id: O05598
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Putative ligase Rv1013
up seq anno feature ids: PRO_0000395881

83332:Rv2764c
gene id: 83332:Rv2764c
uniprot id: P9WFR9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Appears to be functional by complementation study.
up seq anno comments: Appears to be non-functional by complementation study.
up seq anno comments: Nucleophile
up seq anno comments: Removed
up seq anno comments: Thymidylate synthase ThyA
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000140990

83332:Rv3610c
gene id: 83332:Rv3610c
uniprot id: P9WQN3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: ATP-dependent zinc metalloprotease FtsH
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000084644

83332:Rv0839
gene id: 83332:Rv0839
uniprot id: I6X9X6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv2431c
gene id: 83332:Rv2431c
uniprot id: I6X486
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetylserine
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE25
up seq anno comments: Removed
up seq anno feature ids: PRO_0000435110

83332:Rv1666c
gene id: 83332:Rv1666c
uniprot id: P9WPM1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 139
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052300

83332:Rv0734
gene id: 83332:Rv0734
uniprot id: P9WK21
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mass
up seq anno comments: Methionine aminopeptidase 1
up seq anno feature ids: PRO_0000414588

83332:Rv2975a
gene id: 83332:Rv2975a
uniprot id: P0DV54
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Large ribosomal subunit protein bL28C
up seq anno comments: Removed
up seq anno feature ids: PRO_0000455667

83332:Rv1145
gene id: 83332:Rv1145
uniprot id: O06545
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Membrane transport protein MMPL

83332:Rv1498c
gene id: 83332:Rv1498c
uniprot id: P9WLW9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterised methyltransferase Rv1498c
up seq anno feature ids: PRO_0000103860

83332:Rv1990c
gene id: 83332:Rv1990c
uniprot id: P9WLP7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Turn
up seq anno comments: Mycobacterial cidal antitoxin MbcA
up seq anno comments: No longer neutralizes the toxic effect of MbcT.
up seq anno feature ids: PRO_0000014116

83332:Rv3163c
gene id: 83332:Rv3163c
uniprot id: O53313
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: DUF58
up seq anno comments: Disordered

83332:Rv0960
gene id: 83332:Rv0960
uniprot id: P9WFA9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC9
up seq anno feature ids: PRO_0000103755

83332:Rv1795
gene id: 83332:Rv1795
uniprot id: P9WNP9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-5 secretion system protein EccD5
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393237

83332:Rv2983
gene id: 83332:Rv2983
uniprot id: P9WP83
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Phosphoenolpyruvate guanylyltransferase
up seq anno feature ids: PRO_0000398696

83332:Rv1615
gene id: 83332:Rv1615
uniprot id: O06132
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: TM2

83332:Rv2464c
gene id: 83332:Rv2464c
uniprot id: P9WNB9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Zinc Finger
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Zinc Finger
up seq anno comments: Endonuclease 8 1
up seq anno comments: FPG-type
up seq anno comments: Proton donor
up seq anno comments: Proton donor; for beta-elimination activity
up seq anno comments: Proton donor; for delta-elimination activity
up seq anno comments: Removed
up seq anno comments: Schiff-base intermediate with DNA
up seq anno feature ids: PRO_0000170903

83332:Rv3284
gene id: 83332:Rv3284
uniprot id: P9WGC3
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Uncharacterized SufE-like protein Rv3284
up seq anno feature ids: PRO_0000202140

83332:Rv0535
gene id: 83332:Rv0535
uniprot id: O06401
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Important for substrate specificity
up seq anno comments: S-methyl-5'-thioadenosine phosphorylase
up seq anno feature ids: PRO_0000415096

83332:Rv3671c
gene id: 83332:Rv3671c
uniprot id: P9WHR9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Abolishes complementation of the Rv3671c mutant. It does not exhibit autocleavage activity.
up seq anno comments: Cleavage; by autolysis
up seq anno comments: Helical
up seq anno comments: Peptidase S1
up seq anno comments: Proton acceptor
up seq anno comments: Serine protease Rv3671c
up seq anno comments: Significant decrease of protease activity.
up seq anno feature ids: PRO_0000414589

83332:Rv1750c
gene id: 83332:Rv1750c
uniprot id: P72007
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv3472
gene id: 83332:Rv3472
uniprot id: I6YG83
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv3101c
gene id: 83332:Rv3101c
uniprot id: P9WG19
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cell division protein FtsX
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno feature ids: PRO_0000166797

83332:Rv1204c
gene id: 83332:Rv1204c
uniprot id: O05305
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA+ ATPase

83332:Rv1166
gene id: 83332:Rv1166
uniprot id: P9WGU7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Probable monoacyl phosphatidylinositol tetramannoside-binding protein LpqW
up seq anno feature ids: PRO_0000393727

83332:Rv2022c
gene id: 83332:Rv2022c
uniprot id: O53468
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative toxin HigB2
up seq anno feature ids: PRO_0000432913

83332:Rv0653c
gene id: 83332:Rv0653c
uniprot id: P96941
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3786c
gene id: 83332:Rv3786c
uniprot id: P9WKW9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv3786c
up seq anno feature ids: PRO_0000014156

83332:Rv0983
gene id: 83332:Rv0983
uniprot id: O53896
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Charge relay system
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Loss of protease activity. Shows neither autoproteolytic nor proteolytic activity against beta-casein.
up seq anno comments: PDZ
up seq anno comments: Periplasmic
up seq anno comments: Polar residues
up seq anno comments: Serine protease PepD
up seq anno feature ids: PRO_0000450863

83332:Rv2690c
gene id: 83332:Rv2690c
uniprot id: I6Y1H7
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2165c
gene id: 83332:Rv2165c
uniprot id: P9WJP1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribosomal RNA small subunit methyltransferase H
up seq anno feature ids: PRO_0000108667

83332:Rv0479c
gene id: 83332:Rv0479c
uniprot id: P9WKV7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized protein Rv0479c
up seq anno feature ids: PRO_0000103681

83332:Rv0793
gene id: 83332:Rv0793
uniprot id: O86332
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: ABM
up seq anno comments: Putative monooxygenase Rv0793
up seq anno feature ids: PRO_0000420880

83332:Rv0441c
gene id: 83332:Rv0441c
uniprot id: P9WKW3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0441c
up seq anno feature ids: PRO_0000103678

83332:Rv0623
gene id: 83332:Rv0623
uniprot id: P9WJ35
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Turn
up seq anno comments: Antitoxin VapB30
up seq anno feature ids: PRO_0000408074

83332:Rv3351c
gene id: 83332:Rv3351c
uniprot id: O50380
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Berberine/berberine-like

83332:Rv1457c
gene id: 83332:Rv1457c
uniprot id: O86349
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC-2 type transporter transmembrane
up seq anno comments: Helical

83332:Rv1113
gene id: 83332:Rv1113
uniprot id: P9WJ33
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Antitoxin VapB32
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000408076

83332:Rv2807
gene id: 83332:Rv2807
uniprot id: P71644
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Integrase catalytic

83332:Rv2281
gene id: 83332:Rv2281
uniprot id: P9WIA5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative phosphate permease Rv2281
up seq anno feature ids: PRO_0000080801

83332:Rv2635
gene id: 83332:Rv2635
uniprot id: P9WL57
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2635
up seq anno feature ids: PRO_0000014144

83332:Rv1767
gene id: 83332:Rv1767
uniprot id: O06800
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxymuconolactone decarboxylase-like

83332:Rv2110c
gene id: 83332:Rv2110c
uniprot id: P9WHT9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Propeptide
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Propeptide
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Covalent link with the inhibitor MLN-273
up seq anno comments: Loss of proteasome proteolytic activity. This mutant enables optimal growth in vitro and in vivo, confers RNI resistance but is not sufficient for persistence in mice.
up seq anno comments: Nucleophile
up seq anno comments: Proteasome subunit beta
up seq anno comments: Removed in mature form; by autocatalysis
up seq anno feature ids: PRO_0000383485
up seq anno feature ids: PRO_0000383486

83332:Rv2946c
gene id: 83332:Rv2946c
uniprot id: P96285
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acyltransferase
up seq anno comments: Beta-ketoacyl reductase
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase
up seq anno comments: Disordered
up seq anno comments: Enoylreductase
up seq anno comments: For acyltransferase activity
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Polar residues
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Putative inactive phenolphthiocerol synthesis polyketide synthase type I Pks1
up seq anno feature ids: PRO_0000406600

83332:Rv0736
gene id: 83332:Rv0736
uniprot id: P9WJ67
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Anti-sigma-L factor RslA
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Loss of Zn(2+)-binding.
up seq anno comments: No change in Zn(2+)-binding.
up seq anno feature ids: PRO_0000422682

83332:Rv0755c
gene id: 83332:Rv0755c
uniprot id: P9WI37
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE12
up seq anno feature ids: PRO_0000378476

83332:Rv2579
gene id: 83332:Rv2579
uniprot id: P9WMR9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: AB hydrolase-1
up seq anno comments: Haloalkane dehalogenase 3
up seq anno comments: N-acetylthreonine
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000216783

83332:Rv3628
gene id: 83332:Rv3628
uniprot id: P9WI55
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-fold decrease in catalytic activity, and 2-fold decrease in substrate affinity.
up seq anno comments: 4-fold decrease in catalytic activity with Mg(2+) as cofactor. 3-fold increase in catalytic activity with Zn(2+) as cofactor. Shifts the pH for optimal activity to 8.5.
up seq anno comments: Inorganic pyrophosphatase
up seq anno comments: Loss of catalytic activity.
up seq anno comments: Nearly no effect on catalytic activity with Mg(2+) as cofactor. 10-fold increase in catalytic activity with Zn(2+) as cofactor.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000137512

83332:Rv0135c
gene id: 83332:Rv0135c
uniprot id: P96812
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3254
gene id: 83332:Rv3254
uniprot id: O05897
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Propeptide
up seq anno labels: Chain
up seq anno labels: Propeptide
up seq anno comments: Protein Rv3254
up seq anno feature ids: PRO_0000432521
up seq anno feature ids: PRO_0000455444

83332:Rv0500
gene id: 83332:Rv0500
uniprot id: P9WHU7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Pyrroline-5-carboxylate reductase
up seq anno feature ids: PRO_0000187294

83332:Rv1678
gene id: 83332:Rv1678
uniprot id: O53925
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0812
gene id: 83332:Rv0812
uniprot id: Q79FW0
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno comments: Bifunctional aminodeoxychorismate lyase / D-amino acid transaminase
up seq anno comments: Decreases kcat of both reactions.
up seq anno comments: Important for dual ACDL/DAAT activities
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000458669

83332:Rv0319
gene id: 83332:Rv0319
uniprot id: P9WIJ5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Pyrrolidone-carboxylate peptidase
up seq anno feature ids: PRO_0000184724

83332:Rv3441c
gene id: 83332:Rv3441c
uniprot id: P9WN41
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Phosphoglucosamine mutase
up seq anno comments: Phosphoserine
up seq anno comments: Phosphoserine intermediate
up seq anno comments: via phosphate group
up seq anno feature ids: PRO_0000147918

83332:Rv0470A
gene id: 83332:Rv0470A
uniprot id: L7N651
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1156
gene id: 83332:Rv1156
uniprot id: O06554
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HhH-GPD

83332:Rv1510
gene id: 83332:Rv1510
uniprot id: P9WLW1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1510
up seq anno feature ids: PRO_0000103864

83332:Rv2897c
gene id: 83332:Rv2897c
uniprot id: P9WPR1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2897c
up seq anno feature ids: PRO_0000206880

83332:Rv0139
gene id: 83332:Rv0139
uniprot id: P96816
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD-dependent epimerase/dehydratase

83332:Rv3595c
gene id: 83332:Rv3595c
uniprot id: Q6MWV6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv1813c
gene id: 83332:Rv1813c
uniprot id: P9WLS1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Uncharacterized protein Rv1813c
up seq anno feature ids: PRO_0000103898

83332:Rv2329c
gene id: 83332:Rv2329c
uniprot id: P71883
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2291
gene id: 83332:Rv2291
uniprot id: P9WHF5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: Putative thiosulfate sulfurtransferase SseB
up seq anno comments: Rhodanese 1
up seq anno comments: Rhodanese 2
up seq anno feature ids: PRO_0000139419

83332:Rv1626
gene id: 83332:Rv1626
uniprot id: P9WGM3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno comments: 4-aspartylphosphate
up seq anno comments: ANTAR
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Response regulatory
up seq anno comments: Transcriptional regulatory protein PdtaR
up seq anno feature ids: PRO_0000386597

83332:Rv3849
gene id: 83332:Rv3849
uniprot id: P9WJB7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Affects protein stability. Decreases affinity for DNA and dimerization capacity.
up seq anno comments: Affects protein stability. Decreases affinity for DNA. Does not affect dimerization.
up seq anno comments: Decreases affinity for DNA. Does not affect dimerization.
up seq anno comments: Does not affect DNA binding.
up seq anno comments: H-T-H motif
up seq anno comments: Moderate impact on protein stability. Does not affect DNA binding.
up seq anno comments: Nucleoid-associated protein EspR
up seq anno feature ids: PRO_0000393905

83332:Rv2476c
gene id: 83332:Rv2476c
uniprot id: O53203
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: NAD-specific glutamate dehydrogenase
up seq anno feature ids: PRO_0000419536

83332:Rv3367
gene id: 83332:Rv3367
uniprot id: L0TCB8
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv2120c
gene id: 83332:Rv2120c
uniprot id: O33255
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Glycine zipper 2TM
up seq anno comments: Helical

83332:Rv3296
gene id: 83332:Rv3296
uniprot id: P96901
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal

83332:Rv0546c
gene id: 83332:Rv0546c
uniprot id: O06412
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: VOC

83332:Rv3681c
gene id: 83332:Rv3681c
uniprot id: P9WF39
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: Apo-form does not bind DNA.
up seq anno comments: Fully oxidized recombinant protein tagged at both termini.
up seq anno comments: Fully reduced recombinant protein tagged at both termini.
up seq anno comments: Partial loss of the Fe-S center. Complete loss of center and of disulfide reductase; when associated with S-37; S-59 and S-62.
up seq anno comments: Partial loss of the Fe-S center. Complete loss of center and of disulfide reductase; when associated with S-37; S-59 and S-68.
up seq anno comments: Partial loss of the Fe-S center. Complete loss of center and of disulfide reductase; when associated with S-37; S-62 and S-68.
up seq anno comments: Partial loss of the Fe-S center. Complete loss of center and of disulfide reductase; when associated with S-59; S-62 and S-68.
up seq anno comments: Transcriptional regulator WhiB4
up seq anno comments: Upon loss of 4Fe-S clusters
up seq anno feature ids: PRO_0000420383

83332:Rv2295
gene id: 83332:Rv2295
uniprot id: P9WFL7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: UPF0167 protein Rv2295
up seq anno feature ids: PRO_0000209366

83332:Rv1215c
gene id: 83332:Rv1215c
uniprot id: O05316
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Xaa-Pro dipeptidyl-peptidase C-terminal

83332:Rv0663
gene id: 83332:Rv0663
uniprot id: I6XVW9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Sulfatase N-terminal

83332:Rv3797
gene id: 83332:Rv3797
uniprot id: O53577
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle
up seq anno comments: Adaptive response protein AidB N-terminal

83332:Rv1520
gene id: 83332:Rv1520
uniprot id: P9WLV5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1520
up seq anno feature ids: PRO_0000103868

83332:Rv2702
gene id: 83332:Rv2702
uniprot id: P9WIN1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Polyphosphate glucokinase
up seq anno feature ids: PRO_0000058536

83332:Rv0490
gene id: 83332:Rv0490
uniprot id: P9WGK5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Sensor-like histidine kinase SenX3
up seq anno feature ids: PRO_0000074876

83332:Rv1323
gene id: 83332:Rv1323
uniprot id: P9WG69
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Propeptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Propeptide
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Probable acetyl-CoA acetyltransferase
up seq anno comments: Probable acetyl-CoA acetyltransferase, propeptide removed
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno comments: Removed; alternate
up seq anno feature ids: PRO_0000206458
up seq anno feature ids: PRO_0000455386
up seq anno feature ids: PRO_0000455387

83332:Rv0284
gene id: 83332:Rv0284
uniprot id: P9WNA9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: ESX-3 secretion system protein EccC3
up seq anno comments: FtsK 1
up seq anno comments: FtsK 2
up seq anno comments: FtsK 3
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393430

83332:Rv1160
gene id: 83332:Rv1160
uniprot id: P9WIY1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: Nudix box
up seq anno comments: Nudix hydrolase
up seq anno comments: Putative 8-oxo-dGTP diphosphatase 2
up seq anno feature ids: PRO_0000391776

83332:Rv3361c
gene id: 83332:Rv3361c
uniprot id: I6YBX3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Pentapeptide repeat
up seq anno comments: Pentapeptide repeat protein MfpA
up seq anno feature ids: PRO_0000434153

83332:Rv1467c
gene id: 83332:Rv1467c
uniprot id: O53158
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acetyl-CoA dehydrogenase-like C-terminal
up seq anno comments: Acyl-CoA dehydrogenase N-terminal bacteria
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv1124
gene id: 83332:Rv1124
uniprot id: O06576
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv2820c
gene id: 83332:Rv2820c
uniprot id: A0A4Y5QPX8
uniprot id: P9WJF7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CRISPR system Cms protein Csm4
up seq anno comments: Csm4 C-terminal
up seq anno feature ids: PRO_0000418227

83332:Rv1295
gene id: 83332:Rv1295
uniprot id: P9WG59
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylthreonine
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Removed
up seq anno comments: Threonine synthase
up seq anno feature ids: PRO_0000185637

83332:Rv2645
gene id: 83332:Rv2645
uniprot id: P9WL51
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2645
up seq anno feature ids: PRO_0000104080

83332:Rv2956
gene id: 83332:Rv2956
uniprot id: I6Y242
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase FkbM

83332:Rv3487c
gene id: 83332:Rv3487c
uniprot id: O06350
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Propeptide
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Propeptide
up seq anno comments: Carboxylesterase/phospholipase LipF
up seq anno comments: Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole
up seq anno comments: Loss of activity.
up seq anno feature ids: PRO_0000419168
up seq anno feature ids: PRO_0000455443

83332:Rv0685
gene id: 83332:Rv0685
uniprot id: P9WNN1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Elongation factor Tu
up seq anno comments: G1
up seq anno comments: G2
up seq anno comments: G3
up seq anno comments: G4
up seq anno comments: G5
up seq anno comments: tr-type G
up seq anno feature ids: PRO_0000091353

83332:Rv3300c
gene id: 83332:Rv3300c
uniprot id: O07166
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Pseudouridine synthase RsuA/RluA-like

83332:Rv2677c
gene id: 83332:Rv2677c
uniprot id: P9WMP1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Coproporphyrinogen III oxidase
up seq anno feature ids: PRO_0000135265

83332:Rv0145
gene id: 83332:Rv0145
uniprot id: P9WFJ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0145
up seq anno feature ids: PRO_0000361235

83332:Rv3266c
gene id: 83332:Rv3266c
uniprot id: P9WH09
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Could provide a fine-tuning to achieve optimal pKa matching between active site and substrate
up seq anno comments: Proton donor/acceptor
up seq anno comments: dTDP-4-dehydrorhamnose reductase
up seq anno feature ids: PRO_0000395352

83332:Rv0512
gene id: 83332:Rv0512
uniprot id: P9WMP5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Delta-aminolevulinic acid dehydratase
up seq anno comments: Schiff-base intermediate with substrate
up seq anno feature ids: PRO_0000140505

83332:Rv1688
gene id: 83332:Rv1688
uniprot id: P9WJP7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative 3-methyladenine DNA glycosylase
up seq anno feature ids: PRO_0000100094

83332:Rv0916c
gene id: 83332:Rv0916c
uniprot id: I6Y936
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv0329c
gene id: 83332:Rv0329c
uniprot id: O07253
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase type 11

83332:Rv3451
gene id: 83332:Rv3451
uniprot id: P9WP39
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: Disordered
up seq anno comments: Nucleophile
up seq anno comments: Probable carboxylesterase Culp3
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000006451

83332:Rv2907c
gene id: 83332:Rv2907c
uniprot id: P9WH19
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: PRC barrel
up seq anno comments: Ribosome maturation factor RimM
up seq anno feature ids: PRO_0000163320

83332:Rv0149
gene id: 83332:Rv0149
uniprot id: P96826
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Enoyl reductase (ER)

83332:Rv0806c
gene id: 83332:Rv0806c
uniprot id: P9WGD1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Exopolysaccharide phosphotransferase CpsY
up seq anno feature ids: PRO_0000235949

83332:Rv0633c
gene id: 83332:Rv0633c
uniprot id: P96923
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2341
gene id: 83332:Rv2341
uniprot id: P95237
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2122c
gene id: 83332:Rv2122c
uniprot id: P9WMM9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: Phosphoribosyl-ATP pyrophosphatase
up seq anno feature ids: PRO_0000136371

83332:Rv1824
gene id: 83332:Rv1824
uniprot id: P9WLR7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1824
up seq anno feature ids: PRO_0000103900

83332:Rv0447c
gene id: 83332:Rv0447c
uniprot id: O53732
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Tuberculostearic acid methyltransferase UfaA1
up seq anno feature ids: PRO_0000432977

83332:Rv3581c
gene id: 83332:Rv3581c
uniprot id: P9WKG5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000189485

83332:Rv2669
gene id: 83332:Rv2669
uniprot id: P9WQG5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase
up seq anno comments: Uncharacterized N-acetyltransferase Rv2669
up seq anno feature ids: PRO_0000074628

83332:Rv1305
gene id: 83332:Rv1305
uniprot id: P9WPS1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Site
up seq anno labels: Transmembrane
up seq anno comments: ATP synthase subunit c
up seq anno comments: Helical
up seq anno comments: Reversibly protonated during proton transport
up seq anno feature ids: PRO_0000112155

83332:Rv1636
gene id: 83332:Rv1636
uniprot id: P9WFC9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Universal stress protein Rv1636
up seq anno feature ids: PRO_0000396947

83332:Rv2489c
gene id: 83332:Rv2489c
uniprot id: O53214
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv3692
gene id: 83332:Rv3692
uniprot id: I6YGX9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ATPase AAA-3
up seq anno comments: ChlI/MoxR AAA lid
up seq anno comments: Disordered

83332:Rv2305
gene id: 83332:Rv2305
uniprot id: P9WLD1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2305
up seq anno feature ids: PRO_0000104015

83332:Rv3138
gene id: 83332:Rv3138
uniprot id: P95188
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Radical SAM core

83332:Rv2788
gene id: 83332:Rv2788
uniprot id: I6Y1Q2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH dtxR-type

83332:Rv0032
gene id: 83332:Rv0032
uniprot id: P9WQ85
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: KAPA synthase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Putative 8-amino-7-oxononanoate synthase 2
up seq anno comments: Unknown
up seq anno feature ids: PRO_0000420959

83332:Rv2604c
gene id: 83332:Rv2604c
uniprot id: P9WII7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Charge relay system
up seq anno comments: Nucleophile
up seq anno comments: Pyridoxal 5'-phosphate synthase subunit PdxT
up seq anno feature ids: PRO_0000135649

83332:Rv3808c
gene id: 83332:Rv3808c
uniprot id: O53585
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1200-fold decrease in transferase activity. No effect on affinity for the substrate UDP-Galf.
up seq anno comments: 1400-fold decrease in transferase activity. No effect on affinity for the substrate UDP-Galf.
up seq anno comments: 1700-fold decrease in transferase activity. No effect on affinity for the substrate UDP-Galf.
up seq anno comments: Galactofuranosyltransferase GlfT2
up seq anno comments: Loss of transferase activity.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000395356

83332:Rv2435c
gene id: 83332:Rv2435c
uniprot id: P71914
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Guanylate cyclase
up seq anno comments: HAMP
up seq anno comments: Helical

83332:Rv1530
gene id: 83332:Rv1530
uniprot id: P9WQC3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable alcohol dehydrogenase adh
up seq anno feature ids: PRO_0000391340

83332:Rv2371
gene id: 83332:Rv2371
uniprot id: Q79FE9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv1334
gene id: 83332:Rv1334
uniprot id: P9WHS1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: CysO-cysteine peptidase
up seq anno comments: JAMM motif
up seq anno comments: MPN
up seq anno feature ids: PRO_0000014095

83332:Rv0505c
gene id: 83332:Rv0505c
uniprot id: P9WGJ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Nucleophile
up seq anno comments: Phosphoserine phosphatase SerB1
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000156893

83332:Rv1834
gene id: 83332:Rv1834
uniprot id: P9WLR1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative hydrolase LipZ
up seq anno feature ids: PRO_0000103907

83332:Rv3372
gene id: 83332:Rv3372
uniprot id: P9WFZ5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Nucleophile
up seq anno comments: Trehalose-phosphate phosphatase
up seq anno feature ids: PRO_0000370706

83332:Rv0298
gene id: 83332:Rv0298
uniprot id: P9WJ09
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin Rv0298
up seq anno feature ids: PRO_0000406884

83332:Rv1173
gene id: 83332:Rv1173
uniprot id: P9WP77
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CofG-like
up seq anno comments: CofH-like
up seq anno comments: FO synthase
up seq anno comments: Radical SAM core 1
up seq anno comments: Radical SAM core 2
up seq anno feature ids: PRO_0000147772

83332:Rv2005c
gene id: 83332:Rv2005c
uniprot id: P9WLN1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Universal stress protein Rv2005c
up seq anno feature ids: PRO_0000103934

83332:Rv1480
gene id: 83332:Rv1480
uniprot id: P9WLX5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1480
up seq anno feature ids: PRO_0000103849

83332:Rv1647
gene id: 83332:Rv1647
uniprot id: P94982
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Guanylate cyclase

83332:Rv2830c
gene id: 83332:Rv2830c
uniprot id: P71622
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB22
up seq anno feature ids: PRO_0000408047

83332:Rv1838c
gene id: 83332:Rv1838c
uniprot id: P9WFA1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC13
up seq anno feature ids: PRO_0000103911

83332:Rv3478
gene id: 83332:Rv3478
uniprot id: Q6MWX1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE
up seq anno comments: PPE family C-terminal

83332:Rv1797
gene id: 83332:Rv1797
uniprot id: P9WJE3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-5 secretion system protein EccE5
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393872

83332:Rv2657c
gene id: 83332:Rv2657c
uniprot id: I6YE30
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Helix-turn-helix

83332:Rv0556
gene id: 83332:Rv0556
uniprot id: O06422
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3497c
gene id: 83332:Rv3497c
uniprot id: I6YGB1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mce/MlaD

83332:Rv2455c
gene id: 83332:Rv2455c
uniprot id: O53182
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: 2-oxoglutarate oxidoreductase subunit KorA
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000420516

83332:Rv2770c
gene id: 83332:Rv2770c
uniprot id: P9WHZ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE44
up seq anno feature ids: PRO_0000379590

83332:Rv3312c
gene id: 83332:Rv3312c
uniprot id: O53363
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv0195
gene id: 83332:Rv0195
uniprot id: O53646
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH luxR-type

83332:Rv1425
gene id: 83332:Rv1425
uniprot id: P9WKC1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv1425
up seq anno feature ids: PRO_0000222908

83332:Rv3651
gene id: 83332:Rv3651
uniprot id: I6YCP0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Rv3651-like N-terminal
up seq anno comments: Rv3651-like middle

83332:Rv3821
gene id: 83332:Rv3821
uniprot id: O07802
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Sulfolipid-1 exporter Sap
up seq anno feature ids: PRO_0000432808

83332:Rv0525
gene id: 83332:Rv0525
uniprot id: O06391
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Uncharacterized protein Rv0525
up seq anno feature ids: PRO_0000396087

83332:Rv3463
gene id: 83332:Rv3463
uniprot id: I6X7D4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv3811
gene id: 83332:Rv3811
uniprot id: Q79F96
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Peptidoglycan recognition protein family

83332:Rv0999
gene id: 83332:Rv0999
uniprot id: O05582
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF5642

83332:Rv0644c
gene id: 83332:Rv0644c
uniprot id: Q79FX6
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cyclopropane mycolic acid synthase MmaA2
up seq anno comments: N-acetylvaline
up seq anno comments: Removed
up seq anno feature ids: PRO_0000398359

83332:Rv2351c
gene id: 83332:Rv2351c
uniprot id: P9WIB5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno labels: Signal Peptide
up seq anno comments: Phospholipase C A
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000023942

83332:Rv2309A
gene id: 83332:Rv2309A
uniprot id: L7N666
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1491c
gene id: 83332:Rv1491c
uniprot id: P9WFS3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: TVP38/TMEM64 family membrane protein Rv1491c
up seq anno feature ids: PRO_0000198638

83332:Rv3592
gene id: 83332:Rv3592
uniprot id: P9WKH3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ABM
up seq anno comments: Heme oxygenase (mycobilin-producing)
up seq anno comments: Inactive.
up seq anno comments: Transition state stabilizer
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000422665

83332:Rv0821c
gene id: 83332:Rv0821c
uniprot id: P9WI95
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Phosphate-specific transport system accessory protein PhoU homolog 2
up seq anno feature ids: PRO_0000155173

83332:Rv1315
gene id: 83332:Rv1315
uniprot id: P9WJM1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Proton donor
up seq anno comments: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
up seq anno feature ids: PRO_0000178890

83332:Rv2500c
gene id: 83332:Rv2500c
uniprot id: I6Y0W5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv3000
gene id: 83332:Rv3000
uniprot id: I6X5Z8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transporter
up seq anno comments: Helical

83332:Rv2966c
gene id: 83332:Rv2966c
uniprot id: I6XFS7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Beta-hairpin
up seq anno comments: Does not affect nuclear localization.
up seq anno comments: Does not show any significant binding to either DNA or RNA and lacks m2G966 methyltransferase activity.
up seq anno comments: Does not show any significant binding to either DNA or RNA in vitro and lacks m2G966 methyltransferase activity in vivo; when associated with A-12 and A-13.
up seq anno comments: Does not show any significant binding to either DNA or RNA in vitro and lacks m2G966 methyltransferase activity in vivo; when associated with A-3 and A-12.
up seq anno comments: Does not show any significant binding to either DNA or RNA in vitro and lacks m2G966 methyltransferase activity in vivo; when associated with A-3 and A-13.
up seq anno comments: Linker
up seq anno comments: RNA/DNA methyltransferase Rv2966c
up seq anno comments: SAM-MT-fold
up seq anno comments: Shows reduced nuclear localization.
up seq anno comments: Shows reduced nuclear localization; when associated with A-171 and A-177.
up seq anno comments: Shows reduced nuclear localization; when associated with A-171 and A-183.
up seq anno comments: Shows reduced nuclear localization; when associated with A-177 and A-183.
up seq anno feature ids: PRO_0000458904

83332:Rv1962A
gene id: 83332:Rv1962A
uniprot id: P9WF17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Antitoxin VapB35
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000408048

83332:Rv3149
gene id: 83332:Rv3149
uniprot id: P9WIV5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylthreonine
up seq anno comments: NADH-quinone oxidoreductase subunit E
up seq anno comments: Removed
up seq anno feature ids: PRO_0000118696

83332:Rv3697c
gene id: 83332:Rv3697c
uniprot id: P9WF47
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC48
up seq anno feature ids: PRO_0000407899

83332:Rv0043c
gene id: 83332:Rv0043c
uniprot id: P9WMG9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH gntR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0043c
up seq anno feature ids: PRO_0000050695

83332:Rv3664c
gene id: 83332:Rv3664c
uniprot id: L0TEV4
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno feature ids: PRO_5003948398

83332:Rv1436
gene id: 83332:Rv1436
uniprot id: P9WN83
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno comments: Activates thiol group during catalysis
up seq anno comments: Glyceraldehyde-3-phosphate dehydrogenase
up seq anno comments: Loss of dehydrogenase activity.
up seq anno comments: Nucleophile
up seq anno comments: Same dehydrogenase activity compared to the wild-type.
up seq anno feature ids: PRO_0000145671

83332:Rv1235
gene id: 83332:Rv1235
uniprot id: P9WGU9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: Trehalose-binding lipoprotein LpqY
up seq anno feature ids: PRO_0000419317

83332:Rv2617c
gene id: 83332:Rv2617c
uniprot id: I6XER9
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2970c
gene id: 83332:Rv2970c
uniprot id: P95125
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Carboxylic ester hydrolase LipN
up seq anno comments: Loss of activity.
up seq anno comments: No change in activity.
up seq anno feature ids: PRO_0000448853

83332:Rv3479
gene id: 83332:Rv3479
uniprot id: O06342
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Transmembrane
up seq anno comments: DGA/G
up seq anno comments: GXSXG
up seq anno comments: Helical
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized membrane protein Rv3479
up seq anno feature ids: PRO_0000432522

83332:Rv2445c
gene id: 83332:Rv2445c
uniprot id: P9WJH7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Nucleoside diphosphate kinase
up seq anno comments: Pros-phosphohistidine intermediate
up seq anno feature ids: PRO_0000137010

83332:Rv0980c
gene id: 83332:Rv0980c
uniprot id: Q79FU0
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Repeat
up seq anno comments: NHL 1
up seq anno comments: NHL 2
up seq anno comments: NHL 3
up seq anno comments: NHL 4
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS18
up seq anno feature ids: PRO_5008177030

83332:Rv0340
gene id: 83332:Rv0340
uniprot id: O33270
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3271c
gene id: 83332:Rv3271c
uniprot id: P96876
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2379c
gene id: 83332:Rv2379c
uniprot id: O05819
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier

83332:Rv2461c
gene id: 83332:Rv2461c
uniprot id: P9WPC5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-dependent Clp protease proteolytic subunit 1
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000179596

83332:Rv0166
gene id: 83332:Rv0166
uniprot id: O07411
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv1345
gene id: 83332:Rv1345
uniprot id: P9WQ41
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase MbtM
up seq anno feature ids: PRO_0000193141

83332:Rv0634A
gene id: 83332:Rv0634A
uniprot id: P9WKS5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0634A
up seq anno feature ids: PRO_0000399398

83332:Rv2201
gene id: 83332:Rv2201
uniprot id: P9WN33
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Site
up seq anno comments: For GATase activity
up seq anno comments: Glutamine amidotransferase type-2
up seq anno comments: Important for beta-aspartyl-AMP intermediate formation
up seq anno comments: Putative asparagine synthetase [glutamine-hydrolyzing]
up seq anno comments: Removed
up seq anno feature ids: PRO_0000056935

83332:Rv3605c
gene id: 83332:Rv3605c
uniprot id: O06277
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1183
gene id: 83332:Rv1183
uniprot id: P9WJU1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Acyltrehalose exporter MmpL10
up seq anno comments: Helical
up seq anno feature ids: PRO_0000103574

83332:Rv3386
gene id: 83332:Rv3386
uniprot id: O50413
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Transposase InsH N-terminal

83332:Rv0310c
gene id: 83332:Rv0310c
uniprot id: O07237
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv2018
gene id: 83332:Rv2018
uniprot id: O53464
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Putative antitoxin VapB45
up seq anno feature ids: PRO_0000433058

83332:Rv1658
gene id: 83332:Rv1658
uniprot id: P9WPW7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Argininosuccinate synthase
up seq anno feature ids: PRO_0000148616

83332:Rv1850
gene id: 83332:Rv1850
uniprot id: P9WFF1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Sequence Conflict
up seq anno comments: N6-carboxylysine
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno comments: Urease
up seq anno comments: Urease subunit alpha
up seq anno comments: via carbamate group
up seq anno feature ids: PRO_0000067549

83332:Rv3538
gene id: 83332:Rv3538
uniprot id: Q6MWW2
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Enoyl-CoA hydratase ChsH3
up seq anno comments: MaoC-like
up seq anno feature ids: PRO_0000456534

83332:Rv2674
gene id: 83332:Rv2674
uniprot id: I6YA00
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MsrB

83332:Rv3510c
gene id: 83332:Rv3510c
uniprot id: I6Y3Q7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amidohydrolase-related

83332:Rv2139
gene id: 83332:Rv2139
uniprot id: P9WHL1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Dihydroorotate dehydrogenase (quinone)
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000148457

83332:Rv1246c
gene id: 83332:Rv1246c
uniprot id: O50461
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Toxin RelE
up seq anno feature ids: PRO_0000406199

83332:Rv2468c
gene id: 83332:Rv2468c
uniprot id: P9WLA7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2468c
up seq anno feature ids: PRO_0000396081

83332:Rv3324c
gene id: 83332:Rv3324c
uniprot id: P9WJR5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Cyclic pyranopterin monophosphate synthase 3
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000097814

83332:Rv0205
gene id: 83332:Rv0205
uniprot id: P9WFM5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative transport protein Rv0205
up seq anno feature ids: PRO_0000148317

83332:Rv1964
gene id: 83332:Rv1964
uniprot id: O53965
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0003
gene id: 83332:Rv0003
uniprot id: P9WHI9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: DNA replication and repair protein RecF
up seq anno feature ids: PRO_0000196435

83332:Rv0867c
gene id: 83332:Rv0867c
uniprot id: P9WG31
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Signal Peptide
up seq anno comments: 1
up seq anno comments: 10
up seq anno comments: 11
up seq anno comments: 12
up seq anno comments: 12 X 8 AA approximate repeats of A-P-A-D-L-A-P-P
up seq anno comments: 2
up seq anno comments: 3
up seq anno comments: 4
up seq anno comments: 5
up seq anno comments: 6
up seq anno comments: 7
up seq anno comments: 8
up seq anno comments: 9
up seq anno comments: Disordered
up seq anno comments: Pro residues
up seq anno comments: Resuscitation-promoting factor RpfA
up seq anno feature ids: PRO_0000421025

83332:Rv1355c
gene id: 83332:Rv1355c
uniprot id: P9WM11
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1355c
up seq anno feature ids: PRO_0000103825

83332:Rv0828c
gene id: 83332:Rv0828c
uniprot id: O53839
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CMP/dCMP-type deaminase

83332:Rv1010
gene id: 83332:Rv1010
uniprot id: P9WH07
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Ribosomal RNA small subunit methyltransferase A
up seq anno feature ids: PRO_0000101568

83332:Rv1193
gene id: 83332:Rv1193
uniprot id: O05295
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv0655
gene id: 83332:Rv0655
uniprot id: P9WQL5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: ABC transporter
up seq anno comments: N6-acetyllysine
up seq anno comments: Probable ribonucleotide transport ATP-binding protein mkl
up seq anno feature ids: PRO_0000092521

83332:Rv1501
gene id: 83332:Rv1501
uniprot id: P9WI91
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1501
up seq anno feature ids: PRO_0000215234

83332:Rv2367c
gene id: 83332:Rv2367c
uniprot id: P9WGX9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Endoribonuclease YbeY
up seq anno feature ids: PRO_0000102494

83332:Rv1326c
gene id: 83332:Rv1326c
uniprot id: P9WN45
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1,4-alpha-glucan branching enzyme GlgB
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000188718

83332:Rv3011c
gene id: 83332:Rv3011c
uniprot id: P9WQA1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Charge relay system
up seq anno comments: Glutamyl-tRNA(Gln) amidotransferase subunit A
up seq anno feature ids: PRO_0000105181

83332:Rv2161c
gene id: 83332:Rv2161c
uniprot id: O06216
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv0226c
gene id: 83332:Rv0226c
uniprot id: P96408
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1987
gene id: 83332:Rv1987
uniprot id: P9WLQ1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: CBM2
up seq anno comments: Uncharacterized protein Rv1987
up seq anno feature ids: PRO_0000014114

83332:Rv3160c
gene id: 83332:Rv3160c
uniprot id: O53310
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3707c
gene id: 83332:Rv3707c
uniprot id: I6Y4C4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF4185

83332:Rv0957
gene id: 83332:Rv0957
uniprot id: P9WHM7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Bifunctional purine biosynthesis protein PurH
up seq anno comments: MGS-like
up seq anno feature ids: PRO_0000192106

83332:Rv3336c
gene id: 83332:Rv3336c
uniprot id: P9WFT3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Tryptophan--tRNA ligase
up seq anno feature ids: PRO_0000136651

83332:Rv0054
gene id: 83332:Rv0054
uniprot id: P9WGD5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: SSB
up seq anno comments: Single-stranded DNA-binding protein
up seq anno feature ids: PRO_0000096069

83332:Rv3674c
gene id: 83332:Rv3674c
uniprot id: P9WQ11
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Endonuclease III
up seq anno comments: HhH
up seq anno feature ids: PRO_0000102219

83332:Rv1447c
gene id: 83332:Rv1447c
uniprot id: P9WN73
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glucose-6-phosphate 1-dehydrogenase 2
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000068126

83332:Rv2980
gene id: 83332:Rv2980
uniprot id: P95115
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2943A
gene id: 83332:Rv2943A
uniprot id: Q6MX22
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: IstB-like ATP-binding

83332:Rv3489
gene id: 83332:Rv3489
uniprot id: I6YC91
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1088
gene id: 83332:Rv1088
uniprot id: Q79FS8
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE family protein PE9
up seq anno feature ids: PRO_0000438135

83332:Rv0351
gene id: 83332:Rv0351
uniprot id: P9WMT5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: N-acetylthreonine
up seq anno comments: Polar residues
up seq anno comments: Protein GrpE
up seq anno comments: Removed
up seq anno feature ids: PRO_0000113824

83332:Rv2103c
gene id: 83332:Rv2103c
uniprot id: O53501
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC37
up seq anno feature ids: PRO_0000407892

83332:Rv3281
gene id: 83332:Rv3281
uniprot id: P96886
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase epsilon subunit
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000452371

83332:Rv0531
gene id: 83332:Rv0531
uniprot id: O06397
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0177
gene id: 83332:Rv0177
uniprot id: O07421
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2601
gene id: 83332:Rv2601
uniprot id: P9WGE5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: PABS
up seq anno comments: Polyamine aminopropyltransferase
up seq anno comments: Proton acceptor
up seq anno comments: Spermidine synthase
up seq anno feature ids: PRO_0000156488

83332:Rv1020
gene id: 83332:Rv1020
uniprot id: P9WMQ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: DEEQ box
up seq anno comments: Disordered
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno comments: Transcription-repair-coupling factor
up seq anno feature ids: PRO_0000102170

83332:Rv3098c
gene id: 83332:Rv3098c
uniprot id: O05776
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3618
gene id: 83332:Rv3618
uniprot id: I6X7W8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv0847
gene id: 83332:Rv0847
uniprot id: O53859
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: Lipoprotein LpqS
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000433100

83332:Rv0321
gene id: 83332:Rv0321
uniprot id: P9WP17
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Important for bifunctional activity
up seq anno comments: Proton donor/acceptor
up seq anno comments: dCTP deaminase, dUMP-forming
up seq anno feature ids: PRO_0000155997

83332:Rv2029c
gene id: 83332:Rv2029c
uniprot id: P9WID3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ATP-dependent 6-phosphofructokinase isozyme 2
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000392912

83332:Rv3793
gene id: 83332:Rv3793
uniprot id: P9WNL5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Probable arabinosyltransferase C
up seq anno comments: Resistance to EMB.
up seq anno feature ids: PRO_0000220573

83332:Rv2510c
gene id: 83332:Rv2510c
uniprot id: I6Y0X6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Helicase HerA-like C-terminal
up seq anno comments: Pro residues

83332:Rv3607c
gene id: 83332:Rv3607c
uniprot id: P9WNC5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Dihydroneopterin aldolase
up seq anno comments: Protein no longer targeted to encapsulin nanocompartments.
up seq anno comments: Proton donor/acceptor
up seq anno comments: Targeting peptide
up seq anno feature ids: PRO_0000168275

83332:Rv2687c
gene id: 83332:Rv2687c
uniprot id: P9WJB1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Fluoroquinolones export permease protein Rv2687c
up seq anno comments: Helical
up seq anno feature ids: PRO_0000390880

83332:Rv2331
gene id: 83332:Rv2331
uniprot id: P9WLB3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2331
up seq anno feature ids: PRO_0000104030

83332:Rv3170
gene id: 83332:Rv3170
uniprot id: P9WQ15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative flavin-containing monoamine oxidase AofH
up seq anno feature ids: PRO_0000099867

83332:Rv3524
gene id: 83332:Rv3524
uniprot id: I6X7J6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: NHL
up seq anno comments: Polar residues

83332:Rv0967
gene id: 83332:Rv0967
uniprot id: P9WP49
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Turn
up seq anno comments: Copper-sensing transcriptional repressor CsoR
up seq anno comments: Decrease in ability to dissociate from DNA in the presence of copper.
up seq anno comments: Disordered
up seq anno comments: Loss of ability to bind copper; loss of ability to dissociate from DNA in the presence of copper.
up seq anno comments: Loss of ability to bind to DNA; when associated with A-15 and A-36.
up seq anno comments: Loss of ability to bind to DNA; when associated with A-15 and A-52.
up seq anno comments: Loss of ability to bind to DNA; when associated with A-36 and A-52.
up seq anno comments: No effect in ability to bind copper.
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000295581

83332:Rv2150c
gene id: 83332:Rv2150c
uniprot id: P9WN95
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cell division protein FtsZ
up seq anno comments: Decrease in GTPase activity.
up seq anno comments: Reduces FtsZ polymerization and GTP hydrolysis. Does not affect the structure or the stability of the unpolymerized FtsZ.
up seq anno comments: Strong decrease in GTPase activity.
up seq anno feature ids: PRO_0000114365

83332:Rv1975
gene id: 83332:Rv1975
uniprot id: O53976
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: SCP
up seq anno comments: SCP domain-containing protein
up seq anno feature ids: PRO_5030174837

83332:Rv1911c
gene id: 83332:Rv1911c
uniprot id: P9WFN3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Polar residues
up seq anno comments: Prevents bacterial uptake by a human macrophage-like cell line
up seq anno comments: Putative lipoprotein LppC
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000137907

83332:Rv0014c
gene id: 83332:Rv0014c
uniprot id: P9WI81
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Does not affect activity.
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Impairs kinase activity.
up seq anno comments: Lack of autophosphorylation. Decreases affinity for FhaB.
up seq anno comments: N-acetylthreonine
up seq anno comments: PASTA 1
up seq anno comments: PASTA 2
up seq anno comments: PASTA 3
up seq anno comments: PASTA 4
up seq anno comments: Phosphoserine; by autocatalysis
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Reduces activity and autophosphorylation. Decreases interaction with GarA.
up seq anno comments: Removed
up seq anno comments: Serine/threonine-protein kinase PknB
up seq anno feature ids: PRO_0000171208

83332:Rv0879c
gene id: 83332:Rv0879c
uniprot id: P9WKR1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0879c
up seq anno feature ids: PRO_0000103723

83332:Rv1367c
gene id: 83332:Rv1367c
uniprot id: P9WLZ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein Rv1367c
up seq anno feature ids: PRO_0000103836

83332:Rv3108
gene id: 83332:Rv3108
uniprot id: O05785
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0368c
gene id: 83332:Rv0368c
uniprot id: O53703
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: VWFA

83332:Rv1545
gene id: 83332:Rv1545
uniprot id: P9WLU9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1545
up seq anno feature ids: PRO_0000103874

83332:Rv0331
gene id: 83332:Rv0331
uniprot id: O07255
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD/NAD(P)-binding

83332:Rv0747
gene id: 83332:Rv0747
uniprot id: P9WIG1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS10
up seq anno feature ids: PRO_0000023576

83332:Rv1206
gene id: 83332:Rv1206
uniprot id: O05307
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Medium/long-chain-fatty-acid--CoA ligase FadD6
up seq anno feature ids: PRO_0000451298

83332:Rv1336
gene id: 83332:Rv1336
uniprot id: P9WP53
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 700-fold decrease in the rate of the first half-reaction using OPS. Affects neither the rate of the first half-reaction using OAS nor the rate of the second half-reaction using sulfide or CysO-COSH.
up seq anno comments: Decreased lifetime of the alpha-aminoacrylate reaction intermediate, increased susceptibility to oxidation by oxidative agents such as hydrogen peroxide, and partial loss of selectivity towards CysO-COSH as sulfur donor.
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: O-phosphoserine sulfhydrylase
up seq anno feature ids: PRO_0000167112

83332:Rv1861
gene id: 83332:Rv1861
uniprot id: P95154
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2174
gene id: 83332:Rv2174
uniprot id: O53508
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Transmembrane
up seq anno comments: Alpha-(1->6)-mannopyranosyltransferase A
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000420592

83332:Rv3025c
gene id: 83332:Rv3025c
uniprot id: P9WQ71
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: IscS-like cysteine desulfurase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: via persulfide group
up seq anno feature ids: PRO_0000420404

83332:Rv1663
gene id: 83332:Rv1663
uniprot id: O06585
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Carrier
up seq anno comments: Disordered

83332:Rv2801A
gene id: 83332:Rv2801A
uniprot id: P0CL61
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Antitoxin MazE9
up seq anno feature ids: PRO_0000406303

83332:Rv1997
gene id: 83332:Rv1997
uniprot id: P9WPS9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Helical
up seq anno comments: Probable cation-transporting ATPase F
up seq anno feature ids: PRO_0000046343

83332:Rv0630c
gene id: 83332:Rv0630c
uniprot id: P9WMQ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DNA-binding and helicase activity, interacts with RecC
up seq anno comments: For nuclease activity
up seq anno comments: Nuclease activity, interacts with RecD and RecA
up seq anno comments: RecBCD enzyme subunit RecB
up seq anno comments: UvrD-like helicase ATP-binding
up seq anno comments: UvrD-like helicase C-terminal
up seq anno feature ids: PRO_0000102048

83332:Rv3717
gene id: 83332:Rv3717
uniprot id: I6Y4D2
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Loss of catalytic activity.
up seq anno comments: MurNAc-LAA
up seq anno comments: N-acetylmuramoyl-L-alanine amidase Rv3717
up seq anno comments: Polar residues
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_5004159884

83332:Rv1821
gene id: 83332:Rv1821
uniprot id: P9WGP3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Protein translocase subunit SecA 2
up seq anno feature ids: PRO_0000109599

83332:Rv1459c
gene id: 83332:Rv1459c
uniprot id: O53150
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Alpha-(1->6)-mannopyranosyltransferase Rv1459c
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno feature ids: PRO_0000420594

83332:Rv0889c
gene id: 83332:Rv0889c
uniprot id: P9WPD3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Putative citrate synthase 2
up seq anno comments: Removed
up seq anno feature ids: PRO_0000169949

83332:Rv0364
gene id: 83332:Rv0364
uniprot id: P9WP09
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein Rv0364
up seq anno feature ids: PRO_0000161428

83332:Rv3291c
gene id: 83332:Rv3291c
uniprot id: I6YBQ3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH asnC-type

83332:Rv3836
gene id: 83332:Rv3836
uniprot id: P96242
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0187
gene id: 83332:Rv0187
uniprot id: O07431
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: Catechol O-methyltransferase
up seq anno comments: Retains a low but substantial activity.
up seq anno feature ids: PRO_0000448281

83332:Rv1030
gene id: 83332:Rv1030
uniprot id: P9WPU3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Helical
up seq anno comments: Potassium-transporting ATPase ATP-binding subunit
up seq anno feature ids: PRO_0000046126

83332:Rv2785c
gene id: 83332:Rv2785c
uniprot id: P9WH55
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein uS15
up seq anno feature ids: PRO_0000115473

83332:Rv3668c
gene id: 83332:Rv3668c
uniprot id: I6YGW2
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010281220

83332:Rv3630
gene id: 83332:Rv3630
uniprot id: P9WKX9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv3630
up seq anno feature ids: PRO_0000104142

83332:Rv0859
gene id: 83332:Rv0859
uniprot id: O53871
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Proton acceptor
up seq anno comments: Putative acyltransferase Rv0859
up seq anno feature ids: PRO_0000395883

83332:Rv3805c
gene id: 83332:Rv3805c
uniprot id: O53582
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Terminal beta-(1->2)-arabinofuranosyltransferase
up seq anno feature ids: PRO_0000420577

83332:Rv1685c
gene id: 83332:Rv1685c
uniprot id: O33187
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv0660c
gene id: 83332:Rv0660c
uniprot id: O06779
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable antitoxin MazE2
up seq anno feature ids: PRO_0000406297

83332:Rv3705A
gene id: 83332:Rv3705A
uniprot id: I6YGY9
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv1517
gene id: 83332:Rv1517
uniprot id: P71796
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2699c
gene id: 83332:Rv2699c
uniprot id: I6YA17
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2343c
gene id: 83332:Rv2343c
uniprot id: P9WNW1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno parent labels: Zinc Finger
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno labels: Zinc Finger
up seq anno comments: CHC2-type
up seq anno comments: DNA primase
up seq anno comments: Disordered
up seq anno comments: Toprim
up seq anno feature ids: PRO_0000180506

83332:Rv3181c
gene id: 83332:Rv3181c
uniprot id: P9WF15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative antitoxin VapB49
up seq anno feature ids: PRO_0000408049

83332:Rv2525c
gene id: 83332:Rv2525c
uniprot id: I6XEI5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno comments: 83% loss of esterase activity.
up seq anno comments: Complete loss of esterase activity.
up seq anno comments: Putative peptidoglycan hydrolase Rv2525c
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_5003706761

83332:Rv3002c
gene id: 83332:Rv3002c
uniprot id: P9WKJ3
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno comments: ACT
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Putative acetolactate synthase small subunit
up seq anno feature ids: PRO_0000151416

83332:Rv1633
gene id: 83332:Rv1633
uniprot id: P9WFC7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: Beta-hairpin
up seq anno comments: Disordered
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno comments: UVR
up seq anno comments: UvrABC system protein B
up seq anno feature ids: PRO_0000138412

83332:Rv2817c
gene id: 83332:Rv2817c
uniprot id: P9WPJ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: CRISPR-associated endonuclease Cas1
up seq anno feature ids: PRO_0000418217

83332:Rv3303c
gene id: 83332:Rv3303c
uniprot id: P9WHH7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: NAD(P)H dehydrogenase (quinone)
up seq anno feature ids: PRO_0000391461

83332:Rv0553
gene id: 83332:Rv0553
uniprot id: P9WJP3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: o-succinylbenzoate synthase
up seq anno feature ids: PRO_0000171279

83332:Rv3689
gene id: 83332:Rv3689
uniprot id: I6YCR8
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0024
gene id: 83332:Rv0024
uniprot id: P71594
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NlpC/P60

83332:Rv2642
gene id: 83332:Rv2642
uniprot id: P71941
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH arsR-type

83332:Rv3494c
gene id: 83332:Rv3494c
uniprot id: I6YC95
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv3126c
gene id: 83332:Rv3126c
uniprot id: P9WL09
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv3126c
up seq anno feature ids: PRO_0000392937

83332:Rv0378
gene id: 83332:Rv0378
uniprot id: O53713
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1557
gene id: 83332:Rv1557
uniprot id: P9WJU9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport protein MmpL6
up seq anno feature ids: PRO_0000103569

83332:Rv0833
gene id: 83332:Rv0833
uniprot id: Q79FV7
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2615c
gene id: 83332:Rv2615c
uniprot id: Q79FC3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv2039c
gene id: 83332:Rv2039c
uniprot id: O53483
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv0670
gene id: 83332:Rv0670
uniprot id: P9WQ13
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable endonuclease 4
up seq anno feature ids: PRO_0000190860

83332:Rv2216
gene id: 83332:Rv2216
uniprot id: P9WGP7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Epimerase family protein Rv2216
up seq anno feature ids: PRO_0000162407

83332:Rv2709
gene id: 83332:Rv2709
uniprot id: I6YA25
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3035
gene id: 83332:Rv3035
uniprot id: I6XFZ8
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein Rv3035
up seq anno feature ids: PRO_0000432519

83332:Rv2184c
gene id: 83332:Rv2184c
uniprot id: O53518
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein Rv2184c
up seq anno feature ids: PRO_0000456388

83332:Rv0497
gene id: 83332:Rv0497
uniprot id: P9WKU3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv0497
up seq anno feature ids: PRO_0000103699

83332:Rv1675c
gene id: 83332:Rv1675c
uniprot id: P9WMH5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH crp-type
up seq anno comments: HTH-type transcriptional regulator Cmr
up seq anno feature ids: PRO_0000420401

83332:Rv2536
gene id: 83332:Rv2536
uniprot id: P95017
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2008c
gene id: 83332:Rv2008c
uniprot id: P9WLM9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2008c
up seq anno feature ids: PRO_0000103936

83332:Rv0641
gene id: 83332:Rv0641
uniprot id: P9WHC7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL1
up seq anno feature ids: PRO_0000125697

83332:Rv3728
gene id: 83332:Rv3728
uniprot id: O69695
up seq anno parent labels: Active Site
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Cyclic nucleotide-binding
up seq anno comments: DGA/G
up seq anno comments: Disordered
up seq anno comments: GXSXG
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Pro residues
up seq anno comments: Proton acceptor

83332:Rv1507c
gene id: 83332:Rv1507c
uniprot id: P9WLW5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1507c
up seq anno feature ids: PRO_0000103862

83332:Rv1470
gene id: 83332:Rv1470
uniprot id: O53161
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thioredoxin

83332:Rv0899
gene id: 83332:Rv0899
uniprot id: P9WIU5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: BON
up seq anno comments: Decreases structure stability of OmpA-like domain.
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Increases conformational stability of OmpA-like domain. Does not alter peptidoglycan-binding.
up seq anno comments: Loss of peptidoglycan-binding; in association with A236.
up seq anno comments: OmpA-like
up seq anno comments: Peptidoglycan-binding protein ArfA
up seq anno comments: Polar residues
up seq anno comments: Required for protein translocation to the outer membrane
up seq anno feature ids: PRO_0000196259

83332:Rv2654c
gene id: 83332:Rv2654c
uniprot id: P9WJ11
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin Rv2654c
up seq anno feature ids: PRO_0000406888

83332:Rv2131c
gene id: 83332:Rv2131c
uniprot id: P9WKJ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3'-phosphoadenosine 5'-phosphate phosphatase
up seq anno comments: Less than 2% of wild-type IMPase and FBPase activities.
up seq anno comments: Less than 3% of wild-type IMPase and FBPase activities.
up seq anno comments: No effect on IMPase and FBPase activities. Much less sensitive to inhibition by Li(+).
up seq anno comments: Removed
up seq anno feature ids: PRO_0000142551

83332:Rv3846
gene id: 83332:Rv3846
uniprot id: P9WGE7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Superoxide dismutase [Fe]
up seq anno feature ids: PRO_0000159990

83332:Rv2795c
gene id: 83332:Rv2795c
uniprot id: I6YEE1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: [Acyl-carrier-protein] phosphodiesterase PptH
up seq anno feature ids: PRO_0000451443

83332:Rv3678c
gene id: 83332:Rv3678c
uniprot id: I6YGW9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Endoribonuclease L-PSP/chorismate mutase-like

83332:Rv0869c
gene id: 83332:Rv0869c
uniprot id: P9WJS1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: GTP 3',8-cyclase 2
up seq anno comments: Radical SAM core
up seq anno feature ids: PRO_0000152977

83332:Rv1695
gene id: 83332:Rv1695
uniprot id: P9WHV7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes catalytic activity.
up seq anno comments: It promotes stronger allosteric interactions.
up seq anno comments: Lower catalytic efficiency. A perturbation of the allosteric interactions is observed when NAD is used as substrate.
up seq anno comments: NAD kinase
up seq anno comments: Possesses 30% of the activity compared to the wild-type enzyme. While mutant affects the catalytic efficiency, it does not alter the binding affinity for ATP and poly(P). It causes a decrease in the affinity for NAD and alters the allosteric interactions mediated by the dinucleotide, both in the presence of poly(P) and ATP.
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000120635

83332:Rv0977
gene id: 83332:Rv0977
uniprot id: Q79FU3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Aspartic proteinase-like domain
up seq anno comments: D(T/S)G 1
up seq anno comments: D(T/S)G 2
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS16
up seq anno feature ids: PRO_0000438172

83332:Rv0337c
gene id: 83332:Rv0337c
uniprot id: P9WQ91
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Alanine aminotransferase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000123843

83332:Rv3460c
gene id: 83332:Rv3460c
uniprot id: P9WH61
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Small ribosomal subunit protein uS13
up seq anno feature ids: PRO_0000132114

83332:Rv3045
gene id: 83332:Rv3045
uniprot id: P9WQC5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylserine
up seq anno comments: NADP-dependent alcohol dehydrogenase C
up seq anno comments: Removed
up seq anno feature ids: PRO_0000160745

83332:Rv1176c
gene id: 83332:Rv1176c
uniprot id: O50432
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transcription regulator PadR C-terminal
up seq anno comments: Transcription regulator PadR N-terminal

83332:Rv1527c
gene id: 83332:Rv1527c
uniprot id: O53901
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Lipid Binding
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Acyl-ester intermediate; for acyltransferase activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase activity
up seq anno comments: Acyltransferase (AT)
up seq anno comments: Beta-ketoacyl reductase (KR)
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase (DH)
up seq anno comments: Enoylreductase (ER)
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Linker domain (LD)
up seq anno comments: Mycocerosic acid synthase-like polyketide synthase
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Pseudo beta-ketoacyl reductase (PsiKR)
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000437078

83332:Rv1341
gene id: 83332:Rv1341
uniprot id: P9WMR7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: dITP/XTP pyrophosphatase
up seq anno feature ids: PRO_0000178197

83332:Rv0990c
gene id: 83332:Rv0990c
uniprot id: O05573
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SAF

83332:Rv1831
gene id: 83332:Rv1831
uniprot id: P9WLR3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1831
up seq anno feature ids: PRO_0000103905

83332:Rv1643
gene id: 83332:Rv1643
uniprot id: P9WHC5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL20
up seq anno feature ids: PRO_0000177190

83332:Rv3866
gene id: 83332:Rv3866
uniprot id: P96210
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESX-1 secretion-associated protein EspG1
up seq anno feature ids: PRO_0000394152

83332:Rv2497c
gene id: 83332:Rv2497c
uniprot id: P9WIS3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 3-methyl-2-oxobutanoate dehydrogenase subunit alpha
up seq anno feature ids: PRO_0000420518

83332:Rv2827c
gene id: 83332:Rv2827c
uniprot id: P71625
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AbiEi antitoxin C-terminal

83332:Rv3358
gene id: 83332:Rv3358
uniprot id: P9WF09
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Toxin RelK
up seq anno feature ids: PRO_0000216213

83332:Rv0072
gene id: 83332:Rv0072
uniprot id: P9WG17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized ABC transporter permease Rv0072
up seq anno feature ids: PRO_0000395862

83332:Rv3315c
gene id: 83332:Rv3315c
uniprot id: P9WPH3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: CMP/dCMP-type deaminase
up seq anno comments: Cytidine deaminase
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000420699

83332:Rv0564c
gene id: 83332:Rv0564c
uniprot id: P9WN75
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable glycerol-3-phosphate dehydrogenase 2 [NAD(P)+]
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000137997

83332:Rv3699
gene id: 83332:Rv3699
uniprot id: O69667
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv0036c
gene id: 83332:Rv0036c
uniprot id: P9WM91
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0036c
up seq anno feature ids: PRO_0000103652

83332:Rv2314c
gene id: 83332:Rv2314c
uniprot id: P71898
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metalloprotease TldD/E C-terminal

83332:Rv3505
gene id: 83332:Rv3505
uniprot id: I6Y3Q0
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-CoA dehydrogenase FadE27
up seq anno feature ids: PRO_0000438521

83332:Rv3140
gene id: 83332:Rv3140
uniprot id: P95186
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv0392c
gene id: 83332:Rv0392c
uniprot id: P95200
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Type II NADH:quinone oxidoreductase NdhA
up seq anno feature ids: PRO_0000452728

83332:Rv3319
gene id: 83332:Rv3319
uniprot id: O53371
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 4Fe-4S ferredoxin-type

83332:Rv0932c
gene id: 83332:Rv0932c
uniprot id: P9WGT9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Phosphate-binding protein PstS 2
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000031855

83332:Rv1232c
gene id: 83332:Rv1232c
uniprot id: O86315
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CBS

83332:Rv0681
gene id: 83332:Rv0681
uniprot id: O53789
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Almost completely abolishes phosphorylation by PknH.
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Phosphothreonine; by PknH
up seq anno comments: Removed
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0681
up seq anno feature ids: PRO_0000450669

83332:Rv3817
gene id: 83332:Rv3817
uniprot id: O07806
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Aminoglycoside phosphotransferase
up seq anno comments: Proton acceptor

83332:Rv1050
gene id: 83332:Rv1050
uniprot id: O53398
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2226
gene id: 83332:Rv2226
uniprot id: P9WLH9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CHAD
up seq anno comments: CYTH
up seq anno comments: Uncharacterized protein Rv2226
up seq anno feature ids: PRO_0000103979

83332:Rv1881c
gene id: 83332:Rv1881c
uniprot id: O07750
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Probable lipoprotein LppE
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000434268

83332:Rv2719c
gene id: 83332:Rv2719c
uniprot id: I6YA32
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Cell wall hydrolase ChiZ
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: LysM-type
up seq anno feature ids: PRO_0000448834

83332:Rv0508
gene id: 83332:Rv0508
uniprot id: P9WKS9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0508
up seq anno feature ids: PRO_0000103712

83332:Rv2546
gene id: 83332:Rv2546
uniprot id: P95007
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC18
up seq anno feature ids: PRO_0000407877

83332:Rv0652
gene id: 83332:Rv0652
uniprot id: P9WHE3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL12
up seq anno feature ids: PRO_0000157550

83332:Rv2837c
gene id: 83332:Rv2837c
uniprot id: P71615
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Bifunctional oligoribonuclease and PAP phosphatase NrnA
up seq anno feature ids: PRO_0000419753

83332:Rv0082
gene id: 83332:Rv0082
uniprot id: I6XUD2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NADH:ubiquinone oxidoreductase-like 20kDa subunit

83332:Rv3199c
gene id: 83332:Rv3199c
uniprot id: P9WIX5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: NAD-capped RNA hydrolase NudC
up seq anno comments: Nudix box
up seq anno comments: Nudix hydrolase
up seq anno feature ids: PRO_0000056970

83332:Rv1312
gene id: 83332:Rv1312
uniprot id: P9WM29
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1312
up seq anno feature ids: PRO_0000103796

83332:Rv2142c
gene id: 83332:Rv2142c
uniprot id: P9WHG5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Toxin ParE2
up seq anno feature ids: PRO_0000408373

83332:Rv3856c
gene id: 83332:Rv3856c
uniprot id: P96221
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Polymerase/histidinol phosphatase N-terminal

83332:Rv2806
gene id: 83332:Rv2806
uniprot id: I6YAA5
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0202c
gene id: 83332:Rv0202c
uniprot id: P9WJT9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Heme uptake protein MmpL11
up seq anno feature ids: PRO_0000103577

83332:Rv2892c
gene id: 83332:Rv2892c
uniprot id: P9WHZ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized PPE family protein PPE45
up seq anno feature ids: PRO_0000217850

83332:Rv2237
gene id: 83332:Rv2237
uniprot id: P9WLH1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2237
up seq anno feature ids: PRO_0000103985

83332:Rv1068c
gene id: 83332:Rv1068c
uniprot id: P9WIF9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS20
up seq anno feature ids: PRO_0000216163

83332:Rv1707
gene id: 83332:Rv1707
uniprot id: O33206
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: STAS

83332:Rv0028
gene id: 83332:Rv0028
uniprot id: P9WM97
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv0028
up seq anno feature ids: PRO_0000103646

83332:Rv1222
gene id: 83332:Rv1222
uniprot id: L0T905
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Anti-sigma-E factor RseA
up seq anno comments: Considerably reduced interaction with SigE. Complete loss of interaction; when associated with A-70.
up seq anno comments: Considerably reduced interaction with SigE. Complete loss of interaction; when associated with A-73.
up seq anno comments: Disordered
up seq anno comments: Loss of phosphorylation, no protein degradation.
up seq anno comments: No change in interaction with SigE.
up seq anno comments: No change in phosphorylation.
up seq anno comments: Phosphothreonine; by PknB
up seq anno feature ids: PRO_0000422950

83332:Rv3471c
gene id: 83332:Rv3471c
uniprot id: O06336
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Cupin type-1

83332:Rv1186c
gene id: 83332:Rv1186c
uniprot id: O50442
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PucR C-terminal helix-turn-helix

83332:Rv1537
gene id: 83332:Rv1537
uniprot id: P9WNT3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: DNA polymerase IV 1
up seq anno comments: Substrate discrimination
up seq anno comments: UmuC
up seq anno feature ids: PRO_0000173924

83332:Rv0174
gene id: 83332:Rv0174
uniprot id: L0T2W6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv1002c
gene id: 83332:Rv1002c
uniprot id: P9WN05
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Loss of protein mannosyltransferase.
up seq anno comments: Probable dolichyl-phosphate-mannose--protein mannosyltransferase
up seq anno feature ids: PRO_0000121517

83332:Rv3893c
gene id: 83332:Rv3893c
uniprot id: L7N660
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3740c
gene id: 83332:Rv3740c
uniprot id: P9WKA5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv3740c
up seq anno feature ids: PRO_0000222923

83332:Rv1842c
gene id: 83332:Rv1842c
uniprot id: P9WFP3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: CNNM transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0053 protein Rv1842c
up seq anno feature ids: PRO_0000088380

83332:Rv2353c
gene id: 83332:Rv2353c
uniprot id: Q79FF3
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2188c
gene id: 83332:Rv2188c
uniprot id: P9WMZ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase
up seq anno feature ids: PRO_0000393733

83332:Rv3879c
gene id: 83332:Rv3879c
uniprot id: P9WJC1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion-associated protein EspK
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000394149

83332:Rv1655
gene id: 83332:Rv1655
uniprot id: P9WPZ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acetylornithine aminotransferase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylthreonine; partial
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000112756

83332:Rv2507
gene id: 83332:Rv2507
uniprot id: O06170
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv3369
gene id: 83332:Rv3369
uniprot id: O50398
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Pyridoxamine 5'-phosphate oxidase putative

83332:Rv2152c
gene id: 83332:Rv2152c
uniprot id: P9WJL7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: UDP-N-acetylmuramate--L-alanine ligase
up seq anno feature ids: PRO_0000182120

83332:Rv0574c
gene id: 83332:Rv0574c
uniprot id: P9WM79
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable polyglutamine synthesis accessory protein Rv0574c
up seq anno feature ids: PRO_0000392686

83332:Rv3709c
gene id: 83332:Rv3709c
uniprot id: P9WPX3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Splice Variant
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Site
up seq anno labels: Splice Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ACT 1
up seq anno comments: ACT 2
up seq anno comments: Aspartokinase
up seq anno comments: Contribution to the catalysis
up seq anno comments: In isoform Beta.
up seq anno feature ids: PRO_0000002385
up seq anno feature ids: VSP_018663

83332:Rv2327
gene id: 83332:Rv2327
uniprot id: P71885
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH marR-type

83332:Rv3151
gene id: 83332:Rv3151
uniprot id: P9WIV9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: 4Fe-4S His(Cys)3-ligated-type
up seq anno comments: 4Fe-4S Mo/W bis-MGD-type
up seq anno comments: N-acetylthreonine
up seq anno comments: NADH-quinone oxidoreductase subunit G
up seq anno comments: Removed
up seq anno feature ids: PRO_0000118559

83332:Rv0402c
gene id: 83332:Rv0402c
uniprot id: P9WJV9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport protein MmpL1
up seq anno feature ids: PRO_0000103562

83332:Rv1394c
gene id: 83332:Rv1394c
uniprot id: P9WPN3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 132
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052287

83332:Rv1242
gene id: 83332:Rv1242
uniprot id: P9WF69
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribonuclease VapC33
up seq anno feature ids: PRO_0000407890

83332:Rv0692
gene id: 83332:Rv0692
uniprot id: P95038
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Peptide chaperone MftB
up seq anno feature ids: PRO_0000415283

83332:Rv3828c
gene id: 83332:Rv3828c
uniprot id: O07795
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: O-(5'-phospho-DNA)-serine intermediate
up seq anno comments: Resolvase/invertase-type recombinase catalytic

83332:Rv1063c
gene id: 83332:Rv1063c
uniprot id: P9WIY9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: DGA/G
up seq anno comments: Disordered
up seq anno comments: GXSXG
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized NTE family protein Rv1063c
up seq anno feature ids: PRO_0000172534

83332:Rv1352
gene id: 83332:Rv1352
uniprot id: P9WM15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1352
up seq anno feature ids: PRO_0000014097

83332:Rv2556c
gene id: 83332:Rv2556c
uniprot id: P9WFP9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: UPF0047 protein Rv2556c
up seq anno feature ids: PRO_0000088520

83332:Rv1190
gene id: 83332:Rv1190
uniprot id: O86348
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv3394c
gene id: 83332:Rv3394c
uniprot id: O50419
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: UmuC
up seq anno comments: UmuC domain-containing protein
up seq anno feature ids: PRO_5010342987

83332:Rv2363
gene id: 83332:Rv2363
uniprot id: P9WQ99
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Charge relay system
up seq anno comments: Putative amidase AmiA2
up seq anno feature ids: PRO_0000105253

83332:Rv2026c
gene id: 83332:Rv2026c
uniprot id: P9WFD1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Universal stress protein Rv2026c
up seq anno feature ids: PRO_0000396946

83332:Rv2847c
gene id: 83332:Rv2847c
uniprot id: I6X5I7
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Tetrapyrrole methylase

83332:Rv0092
gene id: 83332:Rv0092
uniprot id: P9WPU1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Copper-exporting P-type ATPase
up seq anno comments: HMA
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000046165

83332:Rv1857
gene id: 83332:Rv1857
uniprot id: P9WGU3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Sequence Conflict
up seq anno labels: Signal Peptide
up seq anno comments: Molybdate-binding protein ModA
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000031831

83332:Rv1322
gene id: 83332:Rv1322
uniprot id: P9WM27
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1322
up seq anno feature ids: PRO_0000103802

83332:Rv3019c
gene id: 83332:Rv3019c
uniprot id: P9WNI9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: ESAT-6-like protein EsxR
up seq anno feature ids: PRO_0000167813

83332:Rv2676c
gene id: 83332:Rv2676c
uniprot id: P9WL45
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Mutagenesis Site
up seq anno comments: Coproheme decarboxylase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Strong decrease in heme binding.
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000396082

83332:Rv2852c
gene id: 83332:Rv2852c
uniprot id: P9WJP5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable malate:quinone oxidoreductase
up seq anno feature ids: PRO_0000128721

83332:Rv1479
gene id: 83332:Rv1479
uniprot id: Q79FN7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Chaperone MoxR1
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000458849

83332:Rv3521
gene id: 83332:Rv3521
uniprot id: O53566
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF35

83332:Rv2819c
gene id: 83332:Rv2819c
uniprot id: P9WJF5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: CRISPR system Cms protein Csm5
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000418228

83332:Rv1582c
gene id: 83332:Rv1582c
uniprot id: O06608
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SF3 helicase

83332:Rv0212c
gene id: 83332:Rv0212c
uniprot id: P96394
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: NadR/Ttd14 AAA

83332:Rv3022A
gene id: 83332:Rv3022A
uniprot id: Q6MX17
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3333c
gene id: 83332:Rv3333c
uniprot id: O53383
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DUF732
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv0545c
gene id: 83332:Rv0545c
uniprot id: P9WIA7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Probable low-affinity inorganic phosphate transporter
up seq anno feature ids: PRO_0000080792

83332:Rv2247
gene id: 83332:Rv2247
uniprot id: P9WQH5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta6 subunit
up seq anno comments: CoA carboxyltransferase C-terminal
up seq anno comments: CoA carboxyltransferase N-terminal
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000199800

83332:Rv1168c
gene id: 83332:Rv1168c
uniprot id: P9WI27
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: PPE
up seq anno comments: PPE family protein PPE17
up seq anno feature ids: PRO_0000379109

83332:Rv0040c
gene id: 83332:Rv0040c
uniprot id: P9WIM9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Pro residues
up seq anno comments: Proline-rich 28 kDa antigen
up seq anno feature ids: PRO_0000022094

83332:Rv0361
gene id: 83332:Rv0361
uniprot id: O06311
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv3486
gene id: 83332:Rv3486
uniprot id: O06349
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein Rv3486
up seq anno feature ids: PRO_0000432510

83332:Rv0005
gene id: 83332:Rv0005
uniprot id: P9WG45
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Conflict
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 10% supercoiling, 7% decatenation.
up seq anno comments: 13% supercoiling, 10% decatenation, 42% DNA cleavage in presence of norfloxacin.
up seq anno comments: 15% supercoiling, 19% decatenation, 143% DNA cleavage in presence of norfloxacin.
up seq anno comments: 17-fold increased resistance to fluoroquinolones, slightly increased DNA cleavage in absence of drugs.
up seq anno comments: 18% supercoiling, 11% decatenation, 131% DNA cleavage in presence of norfloxacin.
up seq anno comments: 37% supercoiling, 54% decatenation, 126% DNA cleavage in presence of norfloxacin.
up seq anno comments: <2% supercoiling, 2% decatenation.
up seq anno comments: <2% supercoiling, 3% decatenation.
up seq anno comments: <2% supercoiling, 4% decatenation.
up seq anno comments: <3% supercoiling, 18% decatenation, 75% DNA cleavage in presence of norfloxacin.
up seq anno comments: DNA gyrase subunit B
up seq anno comments: Increased resistance to aminopyrazinamides, however genome not sequenced.
up seq anno comments: Increased resistance to pyrrolamides and novobiocin, however genome not sequenced.
up seq anno comments: Increased susceptibility to fluoroquinolones, half supercoiling activity, no fluoroquinolone-induced DNA cleavage (makes sequence more like E.coli).
up seq anno comments: Interaction with DNA
up seq anno comments: No supercoiling activity.
up seq anno comments: Toprim
up seq anno feature ids: PRO_0000145325

83332:Rv1547
gene id: 83332:Rv1547
uniprot id: P9WNT7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: DNA polymerase III subunit alpha
up seq anno feature ids: PRO_0000103329

83332:Rv0184
gene id: 83332:Rv0184
uniprot id: O07428
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DUF2786
up seq anno comments: Disordered

83332:Rv1017c
gene id: 83332:Rv1017c
uniprot id: P9WKE3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Ribose-phosphate pyrophosphokinase
up seq anno feature ids: PRO_0000141164

83332:Rv0662c
gene id: 83332:Rv0662c
uniprot id: O06777
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB7
up seq anno feature ids: PRO_0000408055

83332:Rv2376c
gene id: 83332:Rv2376c
uniprot id: P9WIN7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Propeptide
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Propeptide
up seq anno labels: Signal Peptide
up seq anno comments: Low molecular weight antigen MTB12
up seq anno feature ids: PRO_0000021777
up seq anno feature ids: PRO_0000021778

83332:Rv2430c
gene id: 83332:Rv2430c
uniprot id: Q79FE1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Turn
up seq anno comments: Does not affect formation of the PE25/PPE41 dimer, but abolishes EspG5 binding to PE25/PPE41.
up seq anno comments: Does not disrupt the interaction with EspG5.
up seq anno comments: PPE family protein PPE41
up seq anno feature ids: PRO_0000435111

83332:Rv0844c
gene id: 83332:Rv0844c
uniprot id: P9WGM5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Complete loss of phosphorylation.
up seq anno comments: H-T-H motif
up seq anno comments: HTH luxR-type
up seq anno comments: Probable transcriptional regulatory protein NarL
up seq anno comments: Response regulatory
up seq anno feature ids: PRO_0000401134

83332:Rv1665
gene id: 83332:Rv1665
uniprot id: P9WPF3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Can catalyze the hydrolysis of palmitoyl-CoA, but cannot produce cyclic polyketide products.
up seq anno comments: Methyl-branched alkylpyrone synthesis polyketide synthase-like Pks11
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000407318

83332:Rv2198c
gene id: 83332:Rv2198c
uniprot id: P9WJT1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: N-acetylserine
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Probable transport accessory protein MmpS3
up seq anno comments: Removed
up seq anno feature ids: PRO_0000216155

83332:Rv2517c
gene id: 83332:Rv2517c
uniprot id: O53222
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv3383c
gene id: 83332:Rv3383c
uniprot id: O50410
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: DDXXD motif
up seq anno comments: Geranylgeranyl diphosphate synthase
up seq anno feature ids: PRO_0000451296

83332:Rv2339
gene id: 83332:Rv2339
uniprot id: P9WJU3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport protein MmpL9
up seq anno feature ids: PRO_0000103573

83332:Rv3167c
gene id: 83332:Rv3167c
uniprot id: O53317
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1253
gene id: 83332:Rv1253
uniprot id: P9WH05
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: ATP-dependent RNA helicase DeaD
up seq anno comments: Basic and acidic residues
up seq anno comments: DEAD box
up seq anno comments: Disordered
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno comments: Q motif
up seq anno feature ids: PRO_0000055106

83332:Rv2987c
gene id: 83332:Rv2987c
uniprot id: P9WK95
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-isopropylmalate dehydratase small subunit
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno feature ids: PRO_0000141840

83332:Rv0702
gene id: 83332:Rv0702
uniprot id: P9WH85
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein uL4
up seq anno feature ids: PRO_0000129247

83332:Rv3838c
gene id: 83332:Rv3838c
uniprot id: P9WIC3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: ACT
up seq anno comments: Essential for activity
up seq anno comments: Prephenate dehydratase
up seq anno feature ids: PRO_0000382029

83332:Rv1075c
gene id: 83332:Rv1075c
uniprot id: O53423
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: Disordered
up seq anno comments: GDSL-like esterase Rv1075c
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Strong decrease in activity.
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000448307

83332:Rv2463
gene id: 83332:Rv2463
uniprot id: O53190
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Beta-lactamase-related

83332:Rv0534c
gene id: 83332:Rv0534c
uniprot id: P9WIP3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: 1,4-dihydroxy-2-naphthoate octaprenyltransferase
up seq anno comments: Helical
up seq anno feature ids: PRO_0000096418

83332:Rv2667
gene id: 83332:Rv2667
uniprot id: P9WPC7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Clp R
up seq anno comments: Repeat 1
up seq anno comments: Repeat 2
up seq anno comments: Uncharacterized protein Rv2667
up seq anno feature ids: PRO_0000191238

83332:Rv1363c
gene id: 83332:Rv1363c
uniprot id: P9WLZ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1363c
up seq anno feature ids: PRO_0000103832

83332:Rv3405c
gene id: 83332:Rv3405c
uniprot id: P9WMC3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Abolishes DNA-binding and repressor activity; when associated with A-52 and A-57.
up seq anno comments: Abolishes DNA-binding and repressor activity; when associated with A-52 and A-62.
up seq anno comments: Abolishes DNA-binding and repressor activity; when associated with A-57 and A-62.
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional repressor Rv3405c
up seq anno feature ids: PRO_0000070672

83332:Rv2036
gene id: 83332:Rv2036
uniprot id: O53480
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Mycothiol-dependent maleylpyruvate isomerase metal-binding

83332:Rv1677
gene id: 83332:Rv1677
uniprot id: I6XYM2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thioredoxin

83332:Rv2860c
gene id: 83332:Rv2860c
uniprot id: I6X5K1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: GS beta-grasp
up seq anno comments: GS catalytic

83332:Rv0103c
gene id: 83332:Rv0103c
uniprot id: P9WPT9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Cation-transporting P-type ATPase B
up seq anno comments: HMA
up seq anno comments: Helical
up seq anno feature ids: PRO_0000046168

83332:Rv1868
gene id: 83332:Rv1868
uniprot id: P95147
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1333
gene id: 83332:Rv1333
uniprot id: P9WM23
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized aminopeptidase Rv1333
up seq anno feature ids: PRO_0000103808

83332:Rv2689c
gene id: 83332:Rv2689c
uniprot id: O07191
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Nucleophile
up seq anno comments: TRAM

83332:Rv1569
gene id: 83332:Rv1569
uniprot id: P9WQ87
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno comments: 8-amino-7-oxononanoate synthase 1
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000163818

83332:Rv0763c
gene id: 83332:Rv0763c
uniprot id: P71820
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ferredoxin Fdx
up seq anno feature ids: PRO_0000456900

83332:Rv2157c
gene id: 83332:Rv2157c
uniprot id: P9WJL1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
up seq anno feature ids: PRO_0000101701

83332:Rv0412c
gene id: 83332:Rv0412c
uniprot id: P96258
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0223c
gene id: 83332:Rv0223c
uniprot id: I6X8S7
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Aldehyde dehydrogenase

83332:Rv3118
gene id: 83332:Rv3118
uniprot id: P0CG95
uniprot id: P0CG96
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Uncharacterized protein Rv0814c
up seq anno comments: Uncharacterized protein Rv3118
up seq anno feature ids: PRO_0000396084
up seq anno feature ids: PRO_0000396092

83332:Rv3156
gene id: 83332:Rv3156
uniprot id: P9WIW1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NADH-quinone oxidoreductase subunit L
up seq anno feature ids: PRO_0000118218

83332:Rv2258c
gene id: 83332:Rv2258c
uniprot id: O53532
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: S-adenosylmethionine-dependent methyltransferase Rv2258c
up seq anno feature ids: PRO_0000450837

83332:Rv1325c
gene id: 83332:Rv1325c
uniprot id: P9WIF7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS24
up seq anno feature ids: PRO_0000023577

83332:Rv0051
gene id: 83332:Rv0051
uniprot id: P71708
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0371c
gene id: 83332:Rv0371c
uniprot id: I6WY86
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MobA-like NTP transferase

83332:Rv3496c
gene id: 83332:Rv3496c
uniprot id: I6XHD6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv0886
gene id: 83332:Rv0886
uniprot id: P9WJI1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: 4Fe-4S ferredoxin-type 1
up seq anno comments: 4Fe-4S ferredoxin-type 2
up seq anno comments: Ferredoxin--NADP reductase
up seq anno comments: Probable ferredoxin/ferredoxin--NADP reductase
up seq anno feature ids: PRO_0000167676

83332:Rv2918c
gene id: 83332:Rv2918c
uniprot id: P9WN29
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ACT 1
up seq anno comments: ACT 2
up seq anno comments: Bifunctional uridylyltransferase/uridylyl-removing enzyme
up seq anno comments: HD
up seq anno comments: Uridylyl-removing
up seq anno comments: Uridylyltransferase
up seq anno feature ids: PRO_0000192745

83332:Rv0706
gene id: 83332:Rv0706
uniprot id: P9WHC1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein uL22
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000125187

83332:Rv1554
gene id: 83332:Rv1554
uniprot id: P9WNB7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Fumarate reductase subunit C
up seq anno comments: Helical
up seq anno feature ids: PRO_0000196531

83332:Rv1898
gene id: 83332:Rv1898
uniprot id: P9WFQ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: UPF0045 protein Rv1898
up seq anno feature ids: PRO_0000147623

83332:Rv1027c
gene id: 83332:Rv1027c
uniprot id: P9WGN1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Complete loss of phosphorylation.
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Response regulatory
up seq anno comments: Transcriptional regulatory protein KdpE
up seq anno feature ids: PRO_0000412199

83332:Rv0672
gene id: 83332:Rv0672
uniprot id: I6X9J0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle
up seq anno comments: Adaptive response protein AidB N-terminal

83332:Rv2388c
gene id: 83332:Rv2388c
uniprot id: P9WP73
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Heme chaperone HemW
up seq anno comments: Radical SAM core
up seq anno feature ids: PRO_0000109944

83332:Rv2531c
gene id: 83332:Rv2531c
uniprot id: I6X4K0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site

83332:Rv1864c
gene id: 83332:Rv1864c
uniprot id: P95151
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MOSC

83332:Rv0856
gene id: 83332:Rv0856
uniprot id: O53868
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Coenzyme Q-binding protein COQ10 START

83332:Rv2563
gene id: 83332:Rv2563
uniprot id: P9WG15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized ABC transporter permease Rv2563
up seq anno feature ids: PRO_0000014134

83332:Rv1344
gene id: 83332:Rv1344
uniprot id: P9WQF1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: Acyl carrier protein MbtL
up seq anno comments: Carrier
up seq anno comments: Lack of phosphopantetheinylation.
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno feature ids: PRO_0000180269

83332:Rv2208
gene id: 83332:Rv2208
uniprot id: P9WP91
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Adenosylcobinamide-GDP ribazoletransferase
up seq anno comments: Helical
up seq anno feature ids: PRO_0000146886

83332:Rv2528c
gene id: 83332:Rv2528c
uniprot id: I6Y9K2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Restriction endonuclease type IV Mrr
up seq anno comments: Restriction system protein Mrr-like N-terminal

83332:Rv0317c
gene id: 83332:Rv0317c
uniprot id: O07244
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno comments: GP-PDE
up seq anno comments: Probable glycerophosphodiester phosphodiesterase 2
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000455760

83332:Rv3032
gene id: 83332:Rv3032
uniprot id: P9WMY9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Glycogen synthase
up seq anno feature ids: PRO_0000413905

83332:Rv2350c
gene id: 83332:Rv2350c
uniprot id: P9WIB3
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Phospholipase C B
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000023943

83332:Rv0244c
gene id: 83332:Rv0244c
uniprot id: O53666
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Broad-specificity linear acyl-CoA dehydrogenase FadE5
up seq anno comments: Decreases affinity for eicosanoyl-CoA; when associated with A-447.
up seq anno comments: Increases affinity for eicosanoyl-CoA; when associated with A-447.
up seq anno comments: Loss of activity.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000452498

83332:Rv2865
gene id: 83332:Rv2865
uniprot id: O33347
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Antitoxin RelF
up seq anno feature ids: PRO_0000406202

83332:Rv3178
gene id: 83332:Rv3178
uniprot id: O53328
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative F420H(2)-dependent quinone reductase Rv3178
up seq anno feature ids: PRO_0000399508

83332:Rv2829c
gene id: 83332:Rv2829c
uniprot id: P71623
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC22
up seq anno feature ids: PRO_0000407881

83332:Rv0074
gene id: 83332:Rv0074
uniprot id: O53619
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amidohydrolase-related

83332:Rv1263
gene id: 83332:Rv1263
uniprot id: P9WQ97
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Charge relay system
up seq anno comments: Putative amidase AmiB2
up seq anno feature ids: PRO_0000105255

83332:Rv3509c
gene id: 83332:Rv3509c
uniprot id: O53554
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Putative acetolactate synthase large subunit IlvX
up seq anno comments: Thiamine pyrophosphate binding
up seq anno feature ids: PRO_0000396953

83332:Rv1086
gene id: 83332:Rv1086
uniprot id: P9WFF5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: (2Z,6E)-farnesyl diphosphate synthase
up seq anno comments: 4-fold decrease in affinity relative to the wild-type and able to synthesize prenyl diphosphates containing 20 and 50 carbon atoms when GPP and EE-FPP are used as the allylic substrates, respectively, whereas the wild-type enzyme generates product that is restricted to 15 carbon atoms with GPP as substrate and does not react with EE-FPP; when associated with G-107.
up seq anno comments: Important for determining product length
up seq anno comments: No detectable activity. 4-fold decrease in affinity relative to the wild-type and able to synthesize prenyl diphosphates containing 20 and 50 carbon atoms when GPP and EE-FPP are used as the allylic substrates, respectively, whereas the wild-type enzyme generates product that is restricted to 15 carbon atoms with GPP as substrate and does not react with EE-FPP; when associated with A-84.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000123748

83332:Rv3136
gene id: 83332:Rv3136
uniprot id: P9WHY3
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: N-acetylmethionine
up seq anno comments: Resistant to 3bMP1 compound. Defective in uptake of propionamide, glucose and glycerol, and is unable to grow on them as the sole carbon sources, but grows normally on hexanamide.
up seq anno comments: Resistant to thio-disaccharide T-6, but not to other thio-functionalized carbohydrate derivatives, such as aminothiadiazole T-23 or thiazoline T-26. Sensitive similarly to wild-type to antitubercular drugs including isoniazid, ethambutol, streptomycin, rifampicin and thiolactomycin.
up seq anno comments: Resistant to thio-disaccharide T-6, but not to other thio-functionalized carbohydrate derivatives, such as aminothiadiazole T-23 or thiazoline T-26. Sensitive similarly to wild-type to antitubercular drugs including isoniazid, ethambutol, streptomycin, rifampicin and thiolactomycin. Reduced uptake of radiolabeled T-6 after its 48-hour incubation with the cell culture, but not after its shorter incubation time. Significantly slower growth compared to the wild-type on minimal medium supplemented with maltose or lactose as the sole carbon and energy sources at both neutral pH and acidic pH 5.7. Growth is promoted in acidic minimal medium by supplementation of glycerol or glucose compared to the wild-type. No effect on growth in rich medium.
up seq anno comments: Resistant to trehalose analog 6-azido trehalose, but not to 2-azido trehalose. Normal growth on trehalose as the sole carbon source.
up seq anno comments: Transporter PPE51
up seq anno feature ids: PRO_0000378485

83332:Rv0550c
gene id: 83332:Rv0550c
uniprot id: P9WJ59
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB3
up seq anno feature ids: PRO_0000408053

83332:Rv0194
gene id: 83332:Rv0194
uniprot id: O53645
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1 1
up seq anno comments: ABC transmembrane type-1 2
up seq anno comments: ABC transporter 1
up seq anno comments: ABC transporter 2
up seq anno comments: Helical
up seq anno comments: Multidrug efflux ATP-binding/permease protein Rv0194
up seq anno feature ids: PRO_0000432861

83332:Rv2769c
gene id: 83332:Rv2769c
uniprot id: Q79FA8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PPE family C-terminal

83332:Rv1908c
gene id: 83332:Rv1908c
uniprot id: I6YBX7
uniprot id: P9WIE5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Conflict
up seq anno labels: Sequence Variant
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 20-fold decrease in the rate of INH-NAD adduct formation. Exhibits significantly reduced affinity for INH (KM is increased by 43-fold).
up seq anno comments: Catalase-peroxidase
up seq anno comments: Exhibits 1.7-fold decreased catalytic efficiency for the activation of INH.
up seq anno comments: Exhibits 2-fold increased affinity for INH.
up seq anno comments: Exhibits 8-fold increased catalytic efficiency for the activation of INH (INH-NAD formation). Possesses an enlarged substrate access channel.
up seq anno comments: In strain: 15726/89; INH-resistant.
up seq anno comments: In strain: H0004/93; INH-resistant.
up seq anno comments: In strain: H0169/93; INH-resistant.
up seq anno comments: In strain: H0181/94, H0452/92, H0948/92 and H0169/93; INH-resistant.
up seq anno comments: In strain: H0251/90; INH-resistant.
up seq anno comments: In strain: H0892/92; INH-resistant.
up seq anno comments: In strain: H0948/92; INH-resistant.
up seq anno comments: Nearly no effect on the kinetic parameters for the activation of INH.
up seq anno comments: Nearly no effect on the kinetic parameters for the catalase and peroxidase activity. Activates INH and mediates InhA inactivation as efficiently as wild-type.
up seq anno comments: Plant heme peroxidase family profile
up seq anno comments: Proton acceptor
up seq anno comments: Transition state stabilizer
up seq anno comments: Tryptophan radical intermediate
up seq anno comments: Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-255); alternate
up seq anno comments: Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-107)
up seq anno comments: Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-107); alternate
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000055574

83332:Rv1377c
gene id: 83332:Rv1377c
uniprot id: P71805
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv0010c
gene id: 83332:Rv0010c
uniprot id: P9WMA3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0010c
up seq anno feature ids: PRO_0000103641

83332:Rv3122
gene id: 83332:Rv3122
uniprot id: O07033
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2228c
gene id: 83332:Rv2228c
uniprot id: P9WLH5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Bifunctional protein Rv2228c
up seq anno comments: Proton donor/acceptor; for phosphatase activity
up seq anno comments: RNase H type-1
up seq anno comments: Tele-phosphohistidine intermediate
up seq anno feature ids: PRO_0000103981

83332:Rv1213
gene id: 83332:Rv1213
uniprot id: P9WN43
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glucose-1-phosphate adenylyltransferase
up seq anno feature ids: PRO_0000195309

83332:Rv2046
gene id: 83332:Rv2046
uniprot id: O53489
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0115
gene id: 83332:Rv0115
uniprot id: O53637
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: D-glycero-alpha-D-manno-heptose 7-phosphate kinase
up seq anno comments: Proton acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000453019

83332:Rv3234c
gene id: 83332:Rv3234c
uniprot id: P9WKC5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable diacyglycerol O-acyltransferase tgs3
up seq anno feature ids: PRO_0000222918

83332:Rv1878
gene id: 83332:Rv1878
uniprot id: O07752
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: GS catalytic

83332:Rv1753c
gene id: 83332:Rv1753c
uniprot id: P9WI15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE24
up seq anno feature ids: PRO_0000378480

83332:Rv3545c
gene id: 83332:Rv3545c
uniprot id: P9WPP1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Steroid C26-monooxygenase
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052280

83332:Rv0773c
gene id: 83332:Rv0773c
uniprot id: I6X9S5
up seq anno parent labels: Active Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno comments: Nucleophile

83332:Rv2171
gene id: 83332:Rv2171
uniprot id: O53505
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Helical
up seq anno comments: Important for bacterial uptake by host macrophages
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Protein LppM
up seq anno comments: Remains cell wall associated, no difference in gel migration, upon overexpression in M.smegmatis.
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_5004158821

83332:Rv2533c
gene id: 83332:Rv2533c
uniprot id: P9WIV1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: Transcription antitermination protein NusB
up seq anno feature ids: PRO_0000176557

83332:Rv3725
gene id: 83332:Rv3725
uniprot id: O69692
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD-dependent epimerase/dehydratase

83332:Rv3360
gene id: 83332:Rv3360
uniprot id: O50389
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FHA

83332:Rv0233
gene id: 83332:Rv0233
uniprot id: P9WH69
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Turn
up seq anno comments: 3-(O4'-tyrosyl)-valine (Val-Tyr)
up seq anno comments: R2-like ligand binding oxidase
up seq anno feature ids: PRO_0000375432

83332:Rv1994c
gene id: 83332:Rv1994c
uniprot id: P9WMI9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes metal-induced derepression.
up seq anno comments: HTH arsR-type
up seq anno comments: HTH-type transcriptional regulator CmtR
up seq anno comments: Loss of repressor activity.
up seq anno comments: No effect.
up seq anno comments: The measured mass is that of a dimer, plus 2 cadmium ions.
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000160629

83332:Rv0064
gene id: 83332:Rv0064
uniprot id: P9WFL5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: UPF0182 protein Rv0064
up seq anno feature ids: PRO_0000157723

83332:Rv0896
gene id: 83332:Rv0896
uniprot id: P9WPD5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Citrate synthase 1
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno feature ids: PRO_0000169948

83332:Rv2928
gene id: 83332:Rv2928
uniprot id: P9WQD5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Loss of activity.
up seq anno comments: Thioesterase TesA
up seq anno feature ids: PRO_0000180368

83332:Rv0716
gene id: 83332:Rv0716
uniprot id: P9WH83
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL5
up seq anno feature ids: PRO_0000124956

83332:Rv1567c
gene id: 83332:Rv1567c
uniprot id: O06623
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1224
gene id: 83332:Rv1224
uniprot id: P9WG99
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Sec-independent protein translocase protein TatB
up seq anno feature ids: PRO_0000192661

83332:Rv0866
gene id: 83332:Rv0866
uniprot id: P9WJR1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Molybdopterin synthase catalytic subunit 2
up seq anno feature ids: PRO_0000163088

83332:Rv1397c
gene id: 83332:Rv1397c
uniprot id: P9WFA7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC10
up seq anno feature ids: PRO_0000407872

83332:Rv1354c
gene id: 83332:Rv1354c
uniprot id: P9WM13
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: EAL
up seq anno comments: GAF
up seq anno comments: GGDEF
up seq anno comments: Uncharacterized protein Rv1354c
up seq anno feature ids: PRO_0000103823

83332:Rv2218
gene id: 83332:Rv2218
uniprot id: P9WK91
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Lipoyl synthase
up seq anno comments: Radical SAM core
up seq anno feature ids: PRO_0000102326

83332:Rv3042c
gene id: 83332:Rv3042c
uniprot id: O53289
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: ACT 1
up seq anno comments: ACT 2
up seq anno comments: Completely abolishes enzymatic activity (PubMed:25521849). Decreases enzymatic activity by 60% (PubMed:25037224).
up seq anno comments: Completely abolishes enzymatic activity.
up seq anno comments: Decreases enzymatic activity by 15%.
up seq anno comments: Decreases enzymatic activity by 50%.
up seq anno comments: Decreases enzymatic activity by 55%. Completely abolishes enzymatic activity, does not elicit cytoskeletal rearrangements, and does not suppress IL-8 production after TNF-alpha stimulation; when associated with N-341.
up seq anno comments: Decreases enzymatic activity by 80%.
up seq anno comments: Decreases enzymatic activity by 85%. Completely abolishes enzymatic activity, does not elicit cytoskeletal rearrangements, and does not suppress IL-8 production after TNF-alpha stimulation; when associated with N-345.
up seq anno comments: Does not bind L-serine and correspondingly no oligomeric transitions is observed in the presence of L-serine.
up seq anno comments: No effect on enzymatic activity.
up seq anno comments: Nucleophile
up seq anno comments: Phosphoserine phosphatase SerB2
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000437672

83332:Rv2017
gene id: 83332:Rv2017
uniprot id: O53463
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH cro/C1-type

83332:Rv2875
gene id: 83332:Rv2875
uniprot id: P9WNF5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: FAS1
up seq anno comments: Immunogenic protein MPT70
up seq anno feature ids: PRO_0000008786

83332:Rv3192
gene id: 83332:Rv3192
uniprot id: O53338
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv0987
gene id: 83332:Rv0987
uniprot id: O53900
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized ABC transporter permease protein Rv0987
up seq anno feature ids: PRO_0000451251

83332:Rv3010c
gene id: 83332:Rv3010c
uniprot id: P9WID7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: ATP-dependent 6-phosphofructokinase
up seq anno comments: Important for substrate specificity; cannot use PPi as phosphoryl donor
up seq anno comments: Proton acceptor
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000111968

83332:Rv3560c
gene id: 83332:Rv3560c
uniprot id: I6Y3V5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Acyl-CoA dehydrogenase IpdE1
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000452315

83332:Rv0417
gene id: 83332:Rv0417
uniprot id: P9WG73
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Schiff-base intermediate with DXP
up seq anno comments: Thiazole synthase
up seq anno feature ids: PRO_0000162832

83332:Rv1396c
gene id: 83332:Rv1396c
uniprot id: P71664
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv0383c
gene id: 83332:Rv0383c
uniprot id: O53718
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3853
gene id: 83332:Rv3853
uniprot id: P9WGY3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
up seq anno feature ids: PRO_0000209623

83332:Rv3221A
gene id: 83332:Rv3221A
uniprot id: P9WJ69
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Anti-sigma factor RshA
up seq anno comments: Inhibits SigH sigma factor activity
up seq anno comments: No in vitro phosphorylation by PknB.
up seq anno comments: Phosphothreonine
up seq anno feature ids: PRO_0000423650

83332:Rv0561c
gene id: 83332:Rv0561c
uniprot id: P9WNY9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Menaquinone reductase
up seq anno feature ids: PRO_0000419774

83332:Rv0204c
gene id: 83332:Rv0204c
uniprot id: I6Y748
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv1920
gene id: 83332:Rv1920
uniprot id: O53962
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv1056
gene id: 83332:Rv1056
uniprot id: O53404
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF427

83332:Rv1390
gene id: 83332:Rv1390
uniprot id: P9WGY5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: DNA-directed RNA polymerase subunit omega
up seq anno feature ids: PRO_0000128952

83332:Rv3137
gene id: 83332:Rv3137
uniprot id: P95189
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Causes a probable loss of enzymatic activity.
up seq anno comments: Histidinol-phosphatase
up seq anno feature ids: PRO_0000404323

83332:Rv3686c
gene id: 83332:Rv3686c
uniprot id: O69654
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0021c
gene id: 83332:Rv0021c
uniprot id: P71591
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nitronate monooxygenase

83332:Rv0389
gene id: 83332:Rv0389
uniprot id: P95197
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ATP-grasp
up seq anno comments: Disordered

83332:Rv0877
gene id: 83332:Rv0877
uniprot id: P9WKR3
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv0877
up seq anno feature ids: PRO_0000103721

83332:Rv2056c
gene id: 83332:Rv2056c
uniprot id: P9WH59
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Small ribosomal subunit protein uS14A
up seq anno feature ids: PRO_0000130912

83332:Rv3825c
gene id: 83332:Rv3825c
uniprot id: P9WQE9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acyl-ester intermediate; for acyltransferase activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase activity
up seq anno comments: Acyltransferase (AT)
up seq anno comments: Beta-ketoacyl reductase (KR)
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase (DH)
up seq anno comments: Enoylreductase (ER)
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Linker domain (LD)
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Phthioceranic/hydroxyphthioceranic acid synthase
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Pseudo beta-ketoacyl reductase (PsiKR)
up seq anno feature ids: PRO_0000329012

83332:Rv2573
gene id: 83332:Rv2573
uniprot id: P9WIL1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: 2-dehydropantoate 2-reductase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000157316

83332:Rv1890c
gene id: 83332:Rv1890c
uniprot id: O07742
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Lipid/polyisoprenoid-binding YceI-like

83332:Rv2539c
gene id: 83332:Rv2539c
uniprot id: P9WPY3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: LID domain
up seq anno comments: Shikimate kinase
up seq anno feature ids: PRO_0000192393

83332:Rv2716
gene id: 83332:Rv2716
uniprot id: P9WL43
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2716
up seq anno feature ids: PRO_0000104083

83332:Rv2366c
gene id: 83332:Rv2366c
uniprot id: P9WFP1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: CNNM transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0053 protein Rv2366c
up seq anno feature ids: PRO_0000088381

83332:Rv0998
gene id: 83332:Rv0998
uniprot id: O05581
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acetyltransferase Pat
up seq anno comments: Completely abolishes the interaction with the aliphatic tail of the substrate lysine.
up seq anno comments: Induces autoacetylation of the new lysine in the absence of cAMP.
up seq anno comments: N-acetyltransferase
up seq anno comments: Substantially decreases the interaction with the aliphatic tail of the substrate lysine.
up seq anno comments: Substantially decreases the interaction with the aliphatic tail of the substrate lysine. Markedly reduced activity, with an altered pH-rate profile and abolishes direct interactions with R-184.
up seq anno feature ids: PRO_0000420362

83332:Rv0785
gene id: 83332:Rv0785
uniprot id: P71838
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: KsdD-like steroid dehydrogenase Rv0785
up seq anno feature ids: PRO_0000403955

83332:Rv2181
gene id: 83332:Rv2181
uniprot id: P9WMZ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol mannoside mannosyltransferase
up seq anno feature ids: PRO_0000393740

83332:Rv2543
gene id: 83332:Rv2543
uniprot id: P9WK81
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppA
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000361670

83332:Rv3024c
gene id: 83332:Rv3024c
uniprot id: P9WJS5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: Interaction with tRNA
up seq anno comments: Nucleophile
up seq anno comments: tRNA-specific 2-thiouridylase MnmA
up seq anno feature ids: PRO_0000121656

83332:Rv3371
gene id: 83332:Rv3371
uniprot id: P9WKA9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv3371
up seq anno feature ids: PRO_0000222919

83332:Rv2004c
gene id: 83332:Rv2004c
uniprot id: P9WLN3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2004c
up seq anno feature ids: PRO_0000103932

83332:Rv0278c
gene id: 83332:Rv0278c
uniprot id: P9WIG3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS3
up seq anno feature ids: PRO_0000023575

83332:Rv2834c
gene id: 83332:Rv2834c
uniprot id: I6Y1U3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv0906
gene id: 83332:Rv0906
uniprot id: P9WKP3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv0906
up seq anno feature ids: PRO_0000014085

83332:Rv2661c
gene id: 83332:Rv2661c
uniprot id: P71958
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1752
gene id: 83332:Rv1752
uniprot id: O06789
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2938
gene id: 83332:Rv2938
uniprot id: P9WG21
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-2
up seq anno comments: Helical
up seq anno comments: Probable doxorubicin resistance ABC transporter permease protein DrrC
up seq anno feature ids: PRO_0000393227

83332:Rv0727c
gene id: 83332:Rv0727c
uniprot id: P95075
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Class II aldolase/adducin N-terminal

83332:Rv1579c
gene id: 83332:Rv1579c
uniprot id: O06611
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1234
gene id: 83332:Rv1234
uniprot id: O50451
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: General stress protein 17M-like
up seq anno comments: Helical

83332:Rv1407
gene id: 83332:Rv1407
uniprot id: P9WGX3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: Putative methyltransferase Rv1407
up seq anno feature ids: PRO_0000211823

83332:Rv2234
gene id: 83332:Rv2234
uniprot id: P9WIA1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 11-fold decrease in catalytic efficiency toward pNPP at pH 7.0.
up seq anno comments: Does not affect nitrosylation. 80% decrease in phosphatase activity.
up seq anno comments: Lack of nitrosylation. Does not affect phosphatase activity.
up seq anno comments: Loss of phosphatase activity.
up seq anno comments: Loss of phosphatase activity. Inhibits its dephosphorylation activity on human VPS33B. 36-fold decrease in catalytic efficiency toward pNPP at pH 7.0.
up seq anno comments: Loss of phosphatase activity. Inhibits its dephosphorylation activity on human VPS33B. Reduces its effect on phagolysosome fusion in infected macrophages. Does not affect nitrosylation.
up seq anno comments: Loss of phosphatase activity. Inhibits its dephosphorylation activity on human VPS33B. Reduces its effect on phagolysosome fusion in infected macrophages. Still binds V-ATPase subunit H. 380-fold decrease in catalytic efficiency toward pNPP at pH 7.0.
up seq anno comments: Loss of phosphatase activity; when associated with E-128.
up seq anno comments: Loss of phosphatase activity; when associated with E-129.
up seq anno comments: Low molecular weight protein-tyrosine phosphatase A
up seq anno comments: Mutant can be phosphorylated.
up seq anno comments: Mutant can be phosphorylated. Lack of phosphorylation and loss of phosphatase activity; when associated with A-128.
up seq anno comments: Mutant can be phosphorylated. Lack of phosphorylation and loss of phosphatase activity; when associated with A-129.
up seq anno comments: No change in phosphatase activity.
up seq anno comments: No longer binds to ubiquitin. Abolishes the Jnk- and p38-dependent production of TNF and IL-1-beta in macrophages. Also abolishes the PtpA-mediated inhibition of phagosome acidification.
up seq anno comments: Nucleophile
up seq anno comments: Phosphothreonine; by PknA
up seq anno comments: Phosphotyrosine
up seq anno comments: Proton donor
up seq anno comments: Retains phosphatase activity but does not bind V-ATPase subunit H. Fails to inhibit V-ATPase trafficking to phagosomes and shows impaired intracellular survival.
up seq anno comments: S-nitrosocysteine
up seq anno comments: Slight decrease in phosphatase activity.
up seq anno comments: Strong decrease in phosphatase activity.
up seq anno comments: UIM-like region
up seq anno feature ids: PRO_0000046567

83332:Rv3053c
gene id: 83332:Rv3053c
uniprot id: I6YB06
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Region
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno comments: Glutaredoxin

83332:Rv1692
gene id: 83332:Rv1692
uniprot id: O33194
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: D-glycerol 3-phosphate phosphatase
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000435901

83332:Rv3241c
gene id: 83332:Rv3241c
uniprot id: O05886
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Ribosome hibernation promotion factor
up seq anno feature ids: PRO_0000436446

83332:Rv2028c
gene id: 83332:Rv2028c
uniprot id: P9WFD9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Universal stress protein Rv2028c
up seq anno feature ids: PRO_0000392627

83332:Rv2888c
gene id: 83332:Rv2888c
uniprot id: P9WQ95
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Charge relay system
up seq anno comments: Putative amidase AmiC
up seq anno feature ids: PRO_0000105258

83332:Rv1524
gene id: 83332:Rv1524
uniprot id: P9WN07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized glycosyltransferase Rv1524
up seq anno feature ids: PRO_0000215623

83332:Rv3202c
gene id: 83332:Rv3202c
uniprot id: O53348
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: UvrD-like helicase ATP-binding
up seq anno comments: UvrD-like helicase C-terminal

83332:Rv3571
gene id: 83332:Rv3571
uniprot id: P9WJ93
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component
up seq anno comments: FAD-binding FR-type
up seq anno feature ids: PRO_0000404100

83332:Rv1662
gene id: 83332:Rv1662
uniprot id: O65933
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv0427c
gene id: 83332:Rv0427c
uniprot id: P96273
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: Endonuclease/exonuclease/phosphatase
up seq anno comments: Important for catalytic activity
up seq anno comments: Interaction with DNA substrate
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer

83332:Rv3863
gene id: 83332:Rv3863
uniprot id: P96214
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3312A
gene id: 83332:Rv3312A
uniprot id: P9WI87
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Pilin
up seq anno feature ids: PRO_0000314591

83332:Rv1109c
gene id: 83332:Rv1109c
uniprot id: P9WM59
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv1109c
up seq anno feature ids: PRO_0000403669

83332:Rv0571c
gene id: 83332:Rv0571c
uniprot id: P9WHK1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative phosphoribosyl transferase Rv0571c
up seq anno feature ids: PRO_0000392688

83332:Rv0738
gene id: 83332:Rv0738
uniprot id: P9WKS3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0738
up seq anno feature ids: PRO_0000403672

83332:Rv0214
gene id: 83332:Rv0214
uniprot id: P96396
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv1066
gene id: 83332:Rv1066
uniprot id: O53414
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rhodanese

83332:Rv3148
gene id: 83332:Rv3148
uniprot id: P9WJH5
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: NADH-quinone oxidoreductase subunit D
up seq anno comments: Removed
up seq anno feature ids: PRO_0000118620

83332:Rv3696c
gene id: 83332:Rv3696c
uniprot id: P9WPK1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glycerol kinase
up seq anno feature ids: PRO_0000059472

83332:Rv0399c
gene id: 83332:Rv0399c
uniprot id: P95207
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: Beta-lactamase-related
up seq anno feature ids: PRO_5039549710

83332:Rv0888
gene id: 83332:Rv0888
uniprot id: P9WKQ1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Beta stranded
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Loss of catalytic activity but still able to mediate uptake of glucose and phosphocholine; when associated with N-353.
up seq anno comments: Loss of catalytic activity but still able to mediate uptake of glucose and phosphocholine; when associated with N-481.
up seq anno comments: Periplasmic
up seq anno comments: Polar residues
up seq anno comments: Sphingomyelinase
up seq anno feature ids: PRO_0000103731

83332:Rv3835
gene id: 83332:Rv3835
uniprot id: P9WKW5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized membrane protein Rv3835
up seq anno feature ids: PRO_0000390678

83332:Rv2584c
gene id: 83332:Rv2584c
uniprot id: P9WQ07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Adenine phosphoribosyltransferase
up seq anno feature ids: PRO_0000149420

83332:Rv3251c
gene id: 83332:Rv3251c
uniprot id: O05894
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rubredoxin-like

83332:Rv0516c
gene id: 83332:Rv0516c
uniprot id: O33361
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: Lack of phosphorylation by PknD. Reduced oprA induction in response to osmotic stress.
up seq anno comments: Osmosensory protein A
up seq anno comments: Phosphothreonine; by PknD
up seq anno comments: STAS
up seq anno feature ids: PRO_0000451030

83332:Rv2726c
gene id: 83332:Rv2726c
uniprot id: P9WP19
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Completely abolishes the diaminopimelate epimerase activity.
up seq anno comments: Could be important to modulate the pK values of the two catalytic cysteine residues
up seq anno comments: Diaminopimelate epimerase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Strongly reduces the diaminopimelate epimerase activity.
up seq anno feature ids: PRO_0000149853

83332:Rv1009
gene id: 83332:Rv1009
uniprot id: P9WG29
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: G5
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Resuscitation-promoting factor RpfB
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000421026

83332:Rv2191
gene id: 83332:Rv2191
uniprot id: P9WLJ1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Exonuclease
up seq anno comments: GIY-YIG
up seq anno comments: Putative bifunctional exonuclease/endonuclease protein Rv2191
up seq anno feature ids: PRO_0000103970

83332:Rv2553c
gene id: 83332:Rv2553c
uniprot id: I6XEK6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Transmembrane
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Important for catalytic activity

83332:Rv3034c
gene id: 83332:Rv3034c
uniprot id: O53281
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Probable acetyltransferase Rv3034c
up seq anno feature ids: PRO_0000413012

83332:Rv0335c
gene id: 83332:Rv0335c
uniprot id: L7N648
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Pro residues

83332:Rv3377c
gene id: 83332:Rv3377c
uniprot id: O50406
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Loss of cyclase activity.
up seq anno comments: No change.
up seq anno comments: Type B diterpene cyclase
up seq anno feature ids: PRO_0000416457

83332:Rv2844
gene id: 83332:Rv2844
uniprot id: I6Y1V1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DUF4439
up seq anno comments: Disordered

83332:Rv0089
gene id: 83332:Rv0089
uniprot id: P9WK03
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized methyltransferase Rv0089
up seq anno feature ids: PRO_0000204441

83332:Rv3388
gene id: 83332:Rv3388
uniprot id: Q6MWX5
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0582
gene id: 83332:Rv0582
uniprot id: O53779
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC26
up seq anno feature ids: PRO_0000407885

83332:Rv2673
gene id: 83332:Rv2673
uniprot id: P9WMZ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Alpha-(1->3)-arabinofuranosyltransferase
up seq anno comments: Helical
up seq anno feature ids: PRO_0000420579

83332:Rv3158
gene id: 83332:Rv3158
uniprot id: P9WIW9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NADH-quinone oxidoreductase subunit N
up seq anno feature ids: PRO_0000117693

83332:Rv0409
gene id: 83332:Rv0409
uniprot id: P9WQH1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Acetate kinase
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000107589

83332:Rv1468c
gene id: 83332:Rv1468c
uniprot id: Q79FP0
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Abolishes interaction with host ubiquitin, impairs host xenophagy and increases bacterial loads in mice with enhanced inflammatory responses.
up seq anno comments: Important for interaction with host ubiquitin
up seq anno comments: PE
up seq anno comments: Reduces interaction with host ubiquitin.
up seq anno comments: Reduces interaction with host ubiquitin. Shows enhanced viability, reduced p62 aggregation and reduced colocalization with LC3 and LAMP1 in BMDMs.
up seq anno comments: UBA
up seq anno comments: Ubiquitin-binding protein Rv1468c
up seq anno feature ids: PRO_5004286516

83332:Rv1589
gene id: 83332:Rv1589
uniprot id: P9WPQ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Biotin synthase
up seq anno comments: N-acetylthreonine
up seq anno comments: Radical SAM core
up seq anno comments: Removed
up seq anno feature ids: PRO_0000185560

83332:Rv3342
gene id: 83332:Rv3342
uniprot id: P9WK01
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized methyltransferase Rv3342
up seq anno feature ids: PRO_0000204443

83332:Rv1417
gene id: 83332:Rv1417
uniprot id: P9WLY1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1417
up seq anno feature ids: PRO_0000103843

83332:Rv3003c
gene id: 83332:Rv3003c
uniprot id: P9WG41
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Acetolactate synthase large subunit IlvB1
up seq anno comments: Disordered
up seq anno comments: Thiamine pyrophosphate binding
up seq anno feature ids: PRO_0000090803

83332:Rv2068c
gene id: 83332:Rv2068c
uniprot id: P9WKD3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 200000-fold decrease in catalytic efficiency with cefamandole as substrate.
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Beta-lactamase
up seq anno comments: Functions as a gatekeeper residue that regulates substrate accessibility to the enzyme active site
up seq anno comments: Increases nucleophilicity of active site Ser
up seq anno comments: Loss of catalytic activity with cefamandole as substrate.
up seq anno comments: No longer exported via the Tat-system. Loss of cell resistance to beta-lactam antibiotics.
up seq anno comments: Only minor impairment of catalytic activity with both nitrocefin and ampicillin. Still inhibited by clavulanate and carbapenems.
up seq anno comments: Proton acceptor
up seq anno comments: Significant increase in ampicillin resistance. 2-fold and 3-fold increase in catalytic efficiency with ampicillin and nitrocefin as substrate, respectively, mainly due to an increase in substrate affinity.
up seq anno comments: Significant reduction of catalytic activity for both nitrocefin and ampicillin. Leads to in vitro clavulanate resistance and decreased susceptibility to carbapenem inhibitors, but is still susceptible to ampicillin-clavulanate in vivo.
up seq anno comments: Significant reduction of catalytic activity for both nitrocefin and ampicillin. Only minor impairment of the inactivation by clavulanate. Larger increase in resistance to carbapenems.
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000017005

83332:Rv2244
gene id: 83332:Rv2244
uniprot id: P9WQF3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes activation by PptT.
up seq anno comments: Carrier
up seq anno comments: Meromycolate extension acyl carrier protein
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno feature ids: PRO_0000180247

83332:Rv1121
gene id: 83332:Rv1121
uniprot id: P9WN71
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glucose-6-phosphate 1-dehydrogenase 1
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000068128

83332:Rv1900c
gene id: 83332:Rv1900c
uniprot id: O07732
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: AB hydrolase-1
up seq anno comments: Bifunctional lipase/adenylate cyclase LipJ
up seq anno comments: Does not substantially affect adenylate cyclase activity but increases activity with GTP.
up seq anno comments: Does not substantially affect adenylate cyclase activity.
up seq anno comments: Guanylate cyclase
up seq anno comments: Loss of adenylate cyclase activity.
up seq anno comments: Loss of lipolytic activity.
up seq anno comments: Substantially affects adenylate cyclase activity.
up seq anno feature ids: PRO_0000458141

83332:Rv3063
gene id: 83332:Rv3063
uniprot id: P9WP47
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Peptide transporter CstA
up seq anno feature ids: PRO_0000190049

83332:Rv0530
gene id: 83332:Rv0530
uniprot id: O06396
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CobQ/CobB/MinD/ParA nucleotide binding
up seq anno comments: Disordered

83332:Rv1702c
gene id: 83332:Rv1702c
uniprot id: P9WLT3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1702cMb1728c
up seq anno feature ids: PRO_0000103894

83332:Rv2072c
gene id: 83332:Rv2072c
uniprot id: P9WGA9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]
up seq anno feature ids: PRO_0000150409

83332:Rv2899c
gene id: 83332:Rv2899c
uniprot id: P9WNF1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: Sulfur carrier protein FdhD
up seq anno feature ids: PRO_0000152912

83332:Rv2038c
gene id: 83332:Rv2038c
uniprot id: O53482
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv2565
gene id: 83332:Rv2565
uniprot id: P9WIY7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: DGA/G
up seq anno comments: GXGXXG
up seq anno comments: GXSXG
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized NTE family protein Rv2565
up seq anno feature ids: PRO_0000172536

83332:Rv1534
gene id: 83332:Rv1534
uniprot id: O08377
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3759c
gene id: 83332:Rv3759c
uniprot id: O69725
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: ABC-type glycine betaine transport system substrate-binding
up seq anno feature ids: PRO_5010212199

83332:Rv2373c
gene id: 83332:Rv2373c
uniprot id: P9WNV7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Site
up seq anno parent labels: Zinc Finger
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Repeat
up seq anno labels: Zinc Finger
up seq anno comments: CR-type
up seq anno comments: CXXCXGXG motif
up seq anno comments: Chaperone protein DnaJ 2
up seq anno comments: J
up seq anno feature ids: PRO_0000070836

83332:Rv3583c
gene id: 83332:Rv3583c
uniprot id: P9WJG3
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: RNA polymerase-binding transcription factor CarD
up seq anno comments: Weakens interaction with RpoB, decreases growth rate and virulence, and increases rifampicin sensitivity. Abolishes interaction with RpoB; when associated with E-25.
up seq anno comments: Weakens interaction with RpoB. Abolishes interaction with RpoB; when associated with E-47.
up seq anno feature ids: PRO_0000420262

83332:Rv0437c
gene id: 83332:Rv0437c
uniprot id: P9WHQ5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Site
up seq anno comments: Cleavage (non-hydrolytic); by autocatalysis
up seq anno comments: Phosphatidylserine decarboxylase alpha chain
up seq anno comments: Phosphatidylserine decarboxylase beta chain
up seq anno comments: Pyruvic acid (Ser); by autocatalysis
up seq anno comments: Schiff-base intermediate with substrate; via pyruvic acid
up seq anno feature ids: PRO_0000029779
up seq anno feature ids: PRO_0000029780

83332:Rv0930
gene id: 83332:Rv0930
uniprot id: P9WG11
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Phosphate transport system permease protein PstA 1
up seq anno feature ids: PRO_0000060201

83332:Rv3876
gene id: 83332:Rv3876
uniprot id: P9WJC5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Does not block ESX-1-mediated secretion during ATP depletion. Lack of ATP-binding.
up seq anno comments: ESX-1 secretion-associated protein EspI
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000394147

83332:Rv1120c
gene id: 83332:Rv1120c
uniprot id: O06572
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Guanylate cyclase

83332:Rv2336
gene id: 83332:Rv2336
uniprot id: P95232
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv0752c
gene id: 83332:Rv0752c
uniprot id: I6Y4R2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv3706c
gene id: 83332:Rv3706c
uniprot id: I6X849
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv1725c
gene id: 83332:Rv1725c
uniprot id: P71983
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH hxlR-type

83332:Rv1243c
gene id: 83332:Rv1243c
uniprot id: Q79FQ7
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv2595
gene id: 83332:Rv2595
uniprot id: P9WFC3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Antitoxin VapB40
up seq anno comments: SpoVT-AbrB
up seq anno feature ids: PRO_0000104063

83332:Rv1239c
gene id: 83332:Rv1239c
uniprot id: O50455
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1556
gene id: 83332:Rv1556
uniprot id: P9WMD1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv1556
up seq anno feature ids: PRO_0000070664

83332:Rv0191
gene id: 83332:Rv0191
uniprot id: P9WJX7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Chloramphenicol efflux pump Rv0191
up seq anno comments: Helical
up seq anno feature ids: PRO_0000390681

83332:Rv2736c
gene id: 83332:Rv2736c
uniprot id: P9WHI1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Regulatory protein RecX
up seq anno feature ids: PRO_0000162450

83332:Rv3261
gene id: 83332:Rv3261
uniprot id: P9WP81
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Phosphoenolpyruvate transferase
up seq anno feature ids: PRO_0000145763

83332:Rv1019
gene id: 83332:Rv1019
uniprot id: P96381
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1210
gene id: 83332:Rv1210
uniprot id: O05311
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Binding Site

83332:Rv0456A
gene id: 83332:Rv0456A
uniprot id: Q6MX40
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable endoribonuclease MazF1
up seq anno feature ids: PRO_0000406304

83332:Rv1674c
gene id: 83332:Rv1674c
uniprot id: O53921
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH arsR-type
up seq anno comments: Rhodanese

83332:Rv3391
gene id: 83332:Rv3391
uniprot id: O50417
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Thioester reductase (TE)

83332:Rv0100
gene id: 83332:Rv0100
uniprot id: P9WM65
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: Acyl carrier protein Rv0100
up seq anno comments: Carrier
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno feature ids: PRO_0000103671

83332:Rv3507
gene id: 83332:Rv3507
uniprot id: Q6MWW9
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0594
gene id: 83332:Rv0594
uniprot id: O07784
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv3727
gene id: 83332:Rv3727
uniprot id: O69694
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Amine oxidase
up seq anno comments: Disordered

83332:Rv3207c
gene id: 83332:Rv3207c
uniprot id: O05859
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Peptidase metallopeptidase

83332:Rv2347c
gene id: 83332:Rv2347c
uniprot id: P9WNI5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: ESAT-6-like protein EsxP
up seq anno feature ids: PRO_0000167815

83332:Rv2686c
gene id: 83332:Rv2686c
uniprot id: P9WJB3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Fluoroquinolones export permease protein Rv2686c
up seq anno comments: Helical
up seq anno feature ids: PRO_0000390879

83332:Rv3542c
gene id: 83332:Rv3542c
uniprot id: I6YGF8
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: 3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase alpha subunit
up seq anno comments: DUF35
up seq anno feature ids: PRO_0000452241

83332:Rv0419
gene id: 83332:Rv0419
uniprot id: P96265
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1562c
gene id: 83332:Rv1562c
uniprot id: P9WQ23
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Disordered
up seq anno comments: Malto-oligosyltrehalose trehalohydrolase
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000054324

83332:Rv3357
gene id: 83332:Rv3357
uniprot id: P9WF25
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Antitoxin RelJ
up seq anno feature ids: PRO_0000213742

83332:Rv0220
gene id: 83332:Rv0220
uniprot id: P96402
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Esterase LipC
up seq anno feature ids: PRO_0000448850

83332:Rv3111
gene id: 83332:Rv3111
uniprot id: P9WJR9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Cyclic pyranopterin monophosphate synthase 1
up seq anno feature ids: PRO_0000097810

83332:Rv0709
gene id: 83332:Rv0709
uniprot id: P9WHA7
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Large ribosomal subunit protein uL29
up seq anno comments: Removed
up seq anno feature ids: PRO_0000130424

83332:Rv3845
gene id: 83332:Rv3845
uniprot id: P96233
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1083
gene id: 83332:Rv1083
uniprot id: O53431
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2254c
gene id: 83332:Rv2254c
uniprot id: O53528
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2748c
gene id: 83332:Rv2748c
uniprot id: P9WNA3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Basic residues
up seq anno comments: Cytoplasmic
up seq anno comments: DNA translocase FtsK
up seq anno comments: Disordered
up seq anno comments: FtsK
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000098271

83332:Rv0542c
gene id: 83332:Rv0542c
uniprot id: P9WQ39
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable 2-succinylbenzoate--CoA ligase
up seq anno feature ids: PRO_0000399477

83332:Rv1714
gene id: 83332:Rv1714
uniprot id: P9WGQ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv1714
up seq anno feature ids: PRO_0000415508

83332:Rv2082
gene id: 83332:Rv2082
uniprot id: Q10690
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized protein Rv2082
up seq anno feature ids: PRO_0000103953

83332:Rv2575
gene id: 83332:Rv2575
uniprot id: P9WL85
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized protein Rv2575
up seq anno feature ids: PRO_0000104056

83332:Rv2383c
gene id: 83332:Rv2383c
uniprot id: P9WQ63
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Adenylation
up seq anno comments: Carrier 1
up seq anno comments: Carrier 2
up seq anno comments: Condensation/cyclization
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: Phenyloxazoline synthase MbtB
up seq anno comments: Thioesterase
up seq anno feature ids: PRO_0000261306

83332:Rv2490c
gene id: 83332:Rv2490c
uniprot id: Q79FD4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv2868c
gene id: 83332:Rv2868c
uniprot id: P9WKG3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000190602

83332:Rv0112
gene id: 83332:Rv0112
uniprot id: O53634
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD(P)-binding

83332:Rv0449c
gene id: 83332:Rv0449c
uniprot id: O53734
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amine oxidase

83332:Rv2205c
gene id: 83332:Rv2205c
uniprot id: P9WMT7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2205c
up seq anno feature ids: PRO_0000071539

83332:Rv3039c
gene id: 83332:Rv3039c
uniprot id: P9WNN3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Important for catalytic activity
up seq anno comments: Probable enoyl-CoA hydratase EchA17
up seq anno feature ids: PRO_0000383565

83332:Rv2698
gene id: 83332:Rv2698
uniprot id: I6X552
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3886c
gene id: 83332:Rv3886c
uniprot id: O05458
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Charge relay system
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Mycosin-2
up seq anno comments: Peptidase S8
up seq anno comments: Pro residues
up seq anno feature ids: PRO_5004157025

83332:Rv1131
gene id: 83332:Rv1131
uniprot id: I6Y9Q3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-methylcitrate synthase
up seq anno feature ids: PRO_0000432969

83332:Rv3716c
gene id: 83332:Rv3716c
uniprot id: P9WNR9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Nucleoid-associated protein Rv3716c
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000170412

83332:Rv1599
gene id: 83332:Rv1599
uniprot id: P9WNW9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Histidinol dehydrogenase
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000135799

83332:Rv3176c
gene id: 83332:Rv3176c
uniprot id: Q6MX03
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv1775
gene id: 83332:Rv1775
uniprot id: O33178
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DAPG hydrolase PhiG

83332:Rv1427c
gene id: 83332:Rv1427c
uniprot id: O06831
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv0059
gene id: 83332:Rv0059
uniprot id: O53604
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ADP-ribosylating turn-turn loop
up seq anno comments: DNA ADP-ribosyl transferase
up seq anno comments: DarT
up seq anno comments: NAD(+)-binding element
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000456050

83332:Rv1387
gene id: 83332:Rv1387
uniprot id: P9WI23
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE20
up seq anno feature ids: PRO_0000379110

83332:Rv2606c
gene id: 83332:Rv2606c
uniprot id: P9WII9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Pyridoxal 5'-phosphate synthase subunit PdxS
up seq anno comments: Schiff-base intermediate with D-ribose 5-phosphate
up seq anno feature ids: PRO_0000109405

83332:Rv1735c
gene id: 83332:Rv1735c
uniprot id: P9WLS5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein Rv1735c
up seq anno feature ids: PRO_0000392908

83332:Rv1250
gene id: 83332:Rv1250
uniprot id: P9WG87
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter Rv1250
up seq anno feature ids: PRO_0000390688

83332:Rv2093c
gene id: 83332:Rv2093c
uniprot id: P9WG97
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Sec-independent protein translocase protein TatC
up seq anno feature ids: PRO_0000098090

83332:Rv1570
gene id: 83332:Rv1570
uniprot id: P9WPQ5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decreases affinity for NaHCO(3) 3-fold, for CTP 1.8-fold and for GTP 3.8-fold.
up seq anno comments: Dethiobiotin synthetase BioD
up seq anno feature ids: PRO_0000187977

83332:Rv3273
gene id: 83332:Rv3273
uniprot id: P96878
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: SLC26A/SulP transporter

83332:Rv1072
gene id: 83332:Rv1072
uniprot id: O53420
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1029
gene id: 83332:Rv1029
uniprot id: P9WKF3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Potassium-transporting ATPase potassium-binding subunit
up seq anno feature ids: PRO_0000166509

83332:Rv2614A
gene id: 83332:Rv2614A
uniprot id: Q79FC4
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0522
gene id: 83332:Rv0522
uniprot id: L7N6B9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Amino acid permease/ SLC12A
up seq anno comments: Helical

83332:Rv2043c
gene id: 83332:Rv2043c
uniprot id: I6XD65
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 10-fold decrease in enzymatic activity with NAM as substrate, and 21-fold decrease in enzymatic activity with PZA as substrate. The mutant has a low metal ion content.
up seq anno comments: 100-fold decrease in enzymatic activity with NAM or PZA as substrate. The mutant has a low metal ion content.
up seq anno comments: 112-fold decrease in enzymatic activity with NAM as substrate, and 164-fold decrease in enzymatic activity with PZA as substrate. The mutant has no detectable iron and manganese.
up seq anno comments: 2.4-fold decrease in enzymatic activity with NAM or PZA as substrate. No effect on metal ion content.
up seq anno comments: 3000-fold decrease in enzymatic activity with NAM as substrate, and 410-fold decrease in enzymatic activity with PZA as substrate. The mutant has no detectable iron and manganese.
up seq anno comments: 5-fold decrease in enzymatic activity with NAM as substrate, and 3-fold decrease in enzymatic activity with PZA as substrate. No effect on metal ion content.
up seq anno comments: Loss of enzymatic activity. No effect on metal ion content.
up seq anno comments: Nicotinamidase/pyrazinamidase
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000438715

83332:Rv3594
gene id: 83332:Rv3594
uniprot id: I6Y3Z2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: N-acetylmuramoyl-L-alanine amidase

83332:Rv0461
gene id: 83332:Rv0461
uniprot id: I6X961
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Protein Rv0461
up seq anno feature ids: PRO_0000456389

83332:Rv3402c
gene id: 83332:Rv3402c
uniprot id: P9WGJ7
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Protein Rv3402c
up seq anno feature ids: PRO_0000104122

83332:Rv2362c
gene id: 83332:Rv2362c
uniprot id: P9WHI5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: DNA repair protein RecO
up seq anno feature ids: PRO_0000204972

83332:Rv3219
gene id: 83332:Rv3219
uniprot id: P9WF43
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: Does not bind 4Fe-4S cluster, binds DNA.
up seq anno comments: For fully alkylated recombinant protein tagged at both termini.
up seq anno comments: Fully oxidized recombinant protein tagged at both termini.
up seq anno comments: Loss of 4Fe-4S cluster, loss of DNA-binding.
up seq anno comments: Loss of DNA-binding, still binds 4Fe-4S cluster.
up seq anno comments: No change in 4Fe-4S cluster, binds DNA.
up seq anno comments: Still binds DNA.
up seq anno comments: Transcriptional regulator WhiB1
up seq anno feature ids: PRO_0000420379

83332:Rv3552
gene id: 83332:Rv3552
uniprot id: P9WPV9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cholesterol ring-cleaving hydrolase IpdB subunit
up seq anno feature ids: PRO_0000157931

83332:Rv0429c
gene id: 83332:Rv0429c
uniprot id: P9WIJ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Peptide deformylase
up seq anno feature ids: PRO_0000082806

83332:Rv1270c
gene id: 83332:Rv1270c
uniprot id: P9WK55
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno comments: Lipoprotein LprA
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: When expressed from this site no longer acts as a TLR2 agonist, suggests active protein is acylated. No glycosylated form detected.
up seq anno feature ids: PRO_0000018135

83332:Rv0109
gene id: 83332:Rv0109
uniprot id: L0T2H7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno feature ids: PRO_5003947676

83332:Rv0230c
gene id: 83332:Rv0230c
uniprot id: P9WHN9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-carboxylysine
up seq anno comments: Phosphotriesterase homology protein
up seq anno comments: via carbamate group
up seq anno feature ids: PRO_0000205363

83332:Rv0720
gene id: 83332:Rv0720
uniprot id: P9WHD1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL18
up seq anno feature ids: PRO_0000131305

83332:Rv3855
gene id: 83332:Rv3855
uniprot id: P9WMC1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional regulator EthR
up seq anno comments: Inhibitor-binding
up seq anno feature ids: PRO_0000398578

83332:Rv1099c
gene id: 83332:Rv1099c
uniprot id: P9WN21
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Fructose-1,6-bisphosphatase class 2
up seq anno comments: N-acetylthreonine; partial
up seq anno comments: Polar residues
up seq anno comments: Removed
up seq anno feature ids: PRO_0000403673

83332:Rv2267c
gene id: 83332:Rv2267c
uniprot id: P9WLG1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Omega-hydroxy-beta-dihydromenaquinone-9 sulfotransferase Stf3
up seq anno feature ids: PRO_0000103993

83332:Rv0903c
gene id: 83332:Rv0903c
uniprot id: P9WGM1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Loss of phosphorylation by PknG/PknK/PknJ.
up seq anno comments: Loss of phosphorylation by PrrB.
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Phosphothreonine
up seq anno comments: Response regulatory
up seq anno comments: Transcriptional regulatory protein PrrA
up seq anno feature ids: PRO_0000081327

83332:Rv0552
gene id: 83332:Rv0552
uniprot id: O06418
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amidohydrolase 3

83332:Rv3493c
gene id: 83332:Rv3493c
uniprot id: I6X7G4
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0724
gene id: 83332:Rv0724
uniprot id: P95072
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Nucleophile
up seq anno comments: Peptidase S49
up seq anno comments: Proton donor/acceptor

83332:Rv1385
gene id: 83332:Rv1385
uniprot id: P9WIU3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Orotidine 5'-phosphate decarboxylase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000134630

83332:Rv0638
gene id: 83332:Rv0638
uniprot id: P9WGN7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Protein translocase subunit SecE
up seq anno feature ids: PRO_0000104168

83332:Rv1221
gene id: 83332:Rv1221
uniprot id: P9WGG7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Splice Variant
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Splice Variant
up seq anno labels: Strand
up seq anno comments: ECF RNA polymerase sigma factor SigE
up seq anno comments: H-T-H motif
up seq anno comments: In isoform 2.
up seq anno comments: In isoform 3.
up seq anno comments: Polymerase core binding
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000422945
up seq anno feature ids: VSP_047440
up seq anno feature ids: VSP_047441
up seq anno feature ids: VSP_047442
up seq anno feature ids: VSP_047443

83332:Rv3422c
gene id: 83332:Rv3422c
uniprot id: P9WFS7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
up seq anno feature ids: PRO_0000096214

83332:Rv2915c
gene id: 83332:Rv2915c
uniprot id: P9WL23
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2915c
up seq anno feature ids: PRO_0000104101

83332:Rv2395
gene id: 83332:Rv2395
uniprot id: P71749
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2881c
gene id: 83332:Rv2881c
uniprot id: P9WPF7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Splice Variant
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Splice Variant
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: In isoform 2.
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphatidate cytidylyltransferase
up seq anno comments: Polar residues
up seq anno comments: Removed
up seq anno feature ids: PRO_0000090743
up seq anno feature ids: VSP_059173
up seq anno feature ids: VSP_059174

83332:Rv1885c
gene id: 83332:Rv1885c
uniprot id: P9WIB9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Turn
up seq anno comments: 10% of the wild-type enzyme activity.
up seq anno comments: 20% of the wild-type enzyme activity.
up seq anno comments: 40% of the wild-type enzyme activity at pH 7.5 and 27% of the wild-type enzyme activity at pH 4.
up seq anno comments: Chorismate mutase
up seq anno comments: Less than 1% of the wild-type enzyme activity.
up seq anno comments: No effect on the enzyme activity.
up seq anno comments: Secreted chorismate mutase
up seq anno feature ids: PRO_0000414906

83332:Rv2215
gene id: 83332:Rv2215
uniprot id: P9WIS7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
up seq anno comments: Disordered
up seq anno comments: Lipoyl-binding 1
up seq anno comments: Lipoyl-binding 2
up seq anno comments: N-acetylalanine
up seq anno comments: N6-lipoyllysine
up seq anno comments: Peripheral subunit-binding (PSBD)
up seq anno comments: Pro residues
up seq anno comments: Removed
up seq anno feature ids: PRO_0000162266

83332:Rv3050c
gene id: 83332:Rv3050c
uniprot id: I6XG13
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Helical

83332:Rv2708c
gene id: 83332:Rv2708c
uniprot id: I6X562
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2885c
gene id: 83332:Rv2885c
uniprot id: P9WL37
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative RNA-guided DNA endonuclease Rv2885c
up seq anno feature ids: PRO_0000014146

83332:Rv1791
gene id: 83332:Rv1791
uniprot id: Q79FK4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3515c
gene id: 83332:Rv3515c
uniprot id: P9WQ51
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Medium/long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligase
up seq anno feature ids: PRO_0000406790

83332:Rv0169
gene id: 83332:Rv0169
uniprot id: Q79FZ9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv0241c
gene id: 83332:Rv0241c
uniprot id: O53664
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-hydroxyacyl-thioester dehydratase X
up seq anno comments: Disordered
up seq anno comments: MaoC-like
up seq anno feature ids: PRO_0000448719

83332:Rv3240c
gene id: 83332:Rv3240c
uniprot id: P9WGP5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Protein translocase subunit SecA 1
up seq anno feature ids: PRO_0000109598

83332:Rv3368c
gene id: 83332:Rv3368c
uniprot id: O50397
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nitroreductase

83332:Rv0609
gene id: 83332:Rv0609
uniprot id: P9WF81
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC28
up seq anno feature ids: PRO_0000221197

83332:Rv1794
gene id: 83332:Rv1794
uniprot id: O53943
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ESX-5 secretion-associated protein EspG5
up seq anno feature ids: PRO_0000435131

83332:Rv1438
gene id: 83332:Rv1438
uniprot id: P9WG43
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Electrophile
up seq anno comments: Proton acceptor
up seq anno comments: Triosephosphate isomerase
up seq anno feature ids: PRO_0000090256

83332:Rv2277c
gene id: 83332:Rv2277c
uniprot id: P9WLF1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: GP-PDE
up seq anno comments: Uncharacterized protein Rv2277c
up seq anno feature ids: PRO_0000014127

83332:Rv1473A
gene id: 83332:Rv1473A
uniprot id: L7N691
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Helix-turn-helix

83332:Rv0071
gene id: 83332:Rv0071
uniprot id: O53616
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Reverse transcriptase

83332:Rv1260
gene id: 83332:Rv1260
uniprot id: P9WM51
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1260
up seq anno feature ids: PRO_0000103777

83332:Rv2109c
gene id: 83332:Rv2109c
uniprot id: P9WHU1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: Markedly increases peptidolytic activity. Disappearance of the apparent obstruction in alpha rings. Designated open-gate mutant.
up seq anno comments: N-acetylserine; partial
up seq anno comments: Phosphothreonine
up seq anno comments: Proteasome subunit alpha
up seq anno comments: Removed
up seq anno feature ids: PRO_0000383482

83332:Rv3283
gene id: 83332:Rv3283
uniprot id: P9WHF7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: N-acetylproline
up seq anno comments: Putative thiosulfate sulfurtransferase SseA
up seq anno comments: Removed
up seq anno comments: Rhodanese 1
up seq anno comments: Rhodanese 2
up seq anno feature ids: PRO_0000139418

83332:Rv0211
gene id: 83332:Rv0211
uniprot id: P9WIH3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphoenolpyruvate carboxykinase [GTP]
up seq anno comments: Removed
up seq anno feature ids: PRO_0000103611

83332:Rv1915
gene id: 83332:Rv1915
uniprot id: O07718
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative isocitrate lyase subunit A
up seq anno feature ids: PRO_0000432566

83332:Rv2407
gene id: 83332:Rv2407
uniprot id: P9WGZ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribonuclease Z
up seq anno feature ids: PRO_0000155879

83332:Rv2744c
gene id: 83332:Rv2744c
uniprot id: P9WHP5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PspA protein
up seq anno feature ids: PRO_0000166290

83332:Rv1729c
gene id: 83332:Rv1729c
uniprot id: P9WFH9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv1729c
up seq anno feature ids: PRO_0000361237

83332:Rv0874c
gene id: 83332:Rv0874c
uniprot id: P9WKR9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0874c
up seq anno feature ids: PRO_0000103717

83332:Rv2053c
gene id: 83332:Rv2053c
uniprot id: O53495
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2225
gene id: 83332:Rv2225
uniprot id: P9WIL7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-methyl-2-oxobutanoate hydroxymethyltransferase
up seq anno comments: Disordered
up seq anno comments: N-acetylserine
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000184864

83332:Rv1694
gene id: 83332:Rv1694
uniprot id: P9WJ63
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
up seq anno comments: S4 RNA-binding
up seq anno feature ids: PRO_0000415501

83332:Rv3412
gene id: 83332:Rv3412
uniprot id: P9WKY9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv3412
up seq anno feature ids: PRO_0000104130

83332:Rv3230c
gene id: 83332:Rv3230c
uniprot id: P9WNE9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: FAD-binding FR-type
up seq anno comments: NADPH oxidoreductase
up seq anno feature ids: PRO_0000392678

83332:Rv1144
gene id: 83332:Rv1144
uniprot id: P9WGQ7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv1144
up seq anno feature ids: PRO_0000415506

83332:Rv1280c
gene id: 83332:Rv1280c
uniprot id: P9WGU5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1280c
up seq anno feature ids: PRO_0000062776

83332:Rv3017c
gene id: 83332:Rv3017c
uniprot id: P9WNJ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxQ
up seq anno feature ids: PRO_0000167810

83332:Rv3902c
gene id: 83332:Rv3902c
uniprot id: O05443
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Immunity factor for TNT
up seq anno feature ids: PRO_0000437788

83332:Rv0770
gene id: 83332:Rv0770
uniprot id: P9WNY3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized oxidoreductase Rv0770
up seq anno feature ids: PRO_0000173069

83332:Rv0730
gene id: 83332:Rv0730
uniprot id: I6XW38
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase

83332:Rv3865
gene id: 83332:Rv3865
uniprot id: P9WJD1
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ESX-1 secretion-associated protein EspF
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000393951

83332:Rv1112
gene id: 83332:Rv1112
uniprot id: O53459
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: OBG-type G
up seq anno comments: TGS

83332:Rv0563
gene id: 83332:Rv0563
uniprot id: P9WHS5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Protease HtpX homolog
up seq anno feature ids: PRO_0000138875

83332:Rv1400c
gene id: 83332:Rv1400c
uniprot id: P71668
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 90% loss of activity.
up seq anno comments: Complete loss of activity.
up seq anno comments: Esterase LipI
up seq anno feature ids: PRO_0000448851

83332:Rv1231c
gene id: 83332:Rv1231c
uniprot id: O86314
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2925c
gene id: 83332:Rv2925c
uniprot id: P9WH03
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: DRBM
up seq anno comments: RNase III
up seq anno comments: Ribonuclease 3
up seq anno feature ids: PRO_0000180413

83332:Rv2065
gene id: 83332:Rv2065
uniprot id: P9WP87
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Precorrin-8X methylmutase
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000135924

83332:Rv1037c
gene id: 83332:Rv1037c
uniprot id: P0DOA6
uniprot id: P0DOA7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: ESAT-6-like protein EsxI
up seq anno comments: ESAT-6-like protein EsxV
up seq anno feature ids: PRO_0000167800
up seq anno feature ids: PRO_0000436928

83332:Rv0134
gene id: 83332:Rv0134
uniprot id: P96811
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv3253c
gene id: 83332:Rv3253c
uniprot id: O05896
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1897c
gene id: 83332:Rv1897c
uniprot id: P9WNS9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: D-aminoacyl-tRNA deacylase
up seq anno comments: Gly-cisPro motif, important for rejection of L-amino acids
up seq anno feature ids: PRO_0000164562

83332:Rv3060c
gene id: 83332:Rv3060c
uniprot id: P95098
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH gntR-type

83332:Rv1840c
gene id: 83332:Rv1840c
uniprot id: P9WIF3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: PE
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS34
up seq anno feature ids: PRO_0000216165

83332:Rv3563
gene id: 83332:Rv3563
uniprot id: P96845
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal

83332:Rv0792c
gene id: 83332:Rv0792c
uniprot id: O86331
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Decreases binding to DNA.
up seq anno comments: H-T-H motif
up seq anno comments: HTH gntR-type
up seq anno comments: HTH-type transcriptional regulator Rv0792c
up seq anno feature ids: PRO_0000458144

83332:Rv3590c
gene id: 83332:Rv3590c
uniprot id: I6XHM5
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv3744
gene id: 83332:Rv3744
uniprot id: O69711
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno comments: Does not affect activity and regulation by metal ions.
up seq anno comments: H-T-H motif
up seq anno comments: HTH arsR-type
up seq anno comments: HTH-type transcriptional regulator NmtR
up seq anno comments: No change in activity. Lack of regulation by metal ions.
up seq anno feature ids: PRO_0000419179

83332:Rv0280
gene id: 83332:Rv0280
uniprot id: P9WI45
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE3
up seq anno feature ids: PRO_0000378474

83332:Rv0251c
gene id: 83332:Rv0251c
uniprot id: O53673
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SHSP

83332:Rv3343c
gene id: 83332:Rv3343c
uniprot id: Q6MWY2
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE54
up seq anno feature ids: PRO_0000378486

83332:Rv3379c
gene id: 83332:Rv3379c
uniprot id: O50408
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transketolase-like pyrimidine-binding

83332:Rv0622
gene id: 83332:Rv0622
uniprot id: P96912
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF732
up seq anno comments: Helical

83332:Rv2012
gene id: 83332:Rv2012
uniprot id: P9WLM3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2012
up seq anno feature ids: PRO_0000103941

83332:Rv1812c
gene id: 83332:Rv1812c
uniprot id: P9WJJ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: NADH dehydrogenase-like protein Rv1812c
up seq anno feature ids: PRO_0000392911

83332:Rv3189
gene id: 83332:Rv3189
uniprot id: O53335
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable NAD(+) phosphorylase Rv3189
up seq anno feature ids: PRO_0000448609

83332:Rv0434
gene id: 83332:Rv0434
uniprot id: P96280
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Lon N-terminal

83332:Rv3568c
gene id: 83332:Rv3568c
uniprot id: P9WNW7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Iron-dependent extradiol dioxygenase
up seq anno comments: VOC 1
up seq anno comments: VOC 2
up seq anno feature ids: PRO_0000404507

83332:Rv0081
gene id: 83332:Rv0081
uniprot id: P9WMI7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: H-T-H motif
up seq anno comments: HTH arsR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0081
up seq anno feature ids: PRO_0000392681

83332:Rv1564c
gene id: 83332:Rv1564c
uniprot id: P9WQ25
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Glycogen operon protein GlgX homolog
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000054307

83332:Rv3007c
gene id: 83332:Rv3007c
uniprot id: O53254
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Flavin reductase like

83332:Rv0913c
gene id: 83332:Rv0913c
uniprot id: I6Y551
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Binding Site

83332:Rv2119
gene id: 83332:Rv2119
uniprot id: O33254
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PD-(D/E)XK endonuclease-like

83332:Rv2945c
gene id: 83332:Rv2945c
uniprot id: P9WK65
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Mass
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Expressed in M.bovis, lipidated and glycosylated.
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative phthiocerol dimycocerosate transporter LppX
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018121

83332:Rv0735
gene id: 83332:Rv0735
uniprot id: P9WGH5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: ECF RNA polymerase sigma factor SigL
up seq anno comments: H-T-H motif
up seq anno comments: Interaction with polymerase core subunit RpoC
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000423646

83332:Rv2418c
gene id: 83332:Rv2418c
uniprot id: P71725
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Diglucosylglycerate octanoyltransferase
up seq anno feature ids: PRO_0000436913

83332:Rv2877c
gene id: 83332:Rv2877c
uniprot id: I6YEL8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Cytochrome C biogenesis protein transmembrane
up seq anno comments: Helical

83332:Rv1739c
gene id: 83332:Rv1739c
uniprot id: P9WGF7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable sulfate transporter Rv1739c
up seq anno comments: Required for sulfate transport in E.coli
up seq anno comments: STAS
up seq anno feature ids: PRO_0000393282

83332:Rv0885
gene id: 83332:Rv0885
uniprot id: P9WKQ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0885
up seq anno feature ids: PRO_0000103727

83332:Rv1414
gene id: 83332:Rv1414
uniprot id: P9WLY3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1414
up seq anno feature ids: PRO_0000103841

83332:Rv2592c
gene id: 83332:Rv2592c
uniprot id: P9WGW1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Head domain (RuvB-H)
up seq anno comments: Holliday junction branch migration complex subunit RuvB
up seq anno comments: Large ATPase domain (RuvB-L)
up seq anno comments: Small ATPAse domain (RuvB-S)
up seq anno feature ids: PRO_0000165562

83332:Rv2236c
gene id: 83332:Rv2236c
uniprot id: P9WP93
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Cobalamin biosynthesis protein CobD
up seq anno comments: Helical
up seq anno feature ids: PRO_0000150933

83332:Rv1704c
gene id: 83332:Rv1704c
uniprot id: O33203
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Amino acid permease/ SLC12A
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2387
gene id: 83332:Rv2387
uniprot id: P71757
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1155
gene id: 83332:Rv1155
uniprot id: O06553
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: F420H(2)-dependent reductase Rv1155
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000399901

83332:Rv2896c
gene id: 83332:Rv2896c
uniprot id: P9WL29
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative DNA processing protein DprA
up seq anno feature ids: PRO_0000104095

83332:Rv0102
gene id: 83332:Rv0102
uniprot id: P9WM63
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0102
up seq anno feature ids: PRO_0000103672

83332:Rv1823
gene id: 83332:Rv1823
uniprot id: P9WFG1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0749 protein Rv1823
up seq anno feature ids: PRO_0000014110

83332:Rv3031
gene id: 83332:Rv3031
uniprot id: P9WQ27
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: Probable 1,4-alpha-glucan branching enzyme Rv3031
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000413972

83332:Rv3913
gene id: 83332:Rv3913
uniprot id: P9WHH1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphotyrosine; by PtkA
up seq anno comments: Redox-active
up seq anno comments: Removed
up seq anno comments: Significantly reduces phosphorylation.
up seq anno comments: Thioredoxin reductase
up seq anno feature ids: PRO_0000166741

83332:Rv0780
gene id: 83332:Rv0780
uniprot id: P9WHN1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: Phosphoribosylaminoimidazole-succinocarboxamide synthase
up seq anno feature ids: PRO_0000100843

83332:Rv1123c
gene id: 83332:Rv1123c
uniprot id: O06575
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv3350c
gene id: 83332:Rv3350c
uniprot id: Q6MWX8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE

83332:Rv0579
gene id: 83332:Rv0579
uniprot id: O53776
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Mut7-C RNAse
up seq anno comments: Ubiquitin Mut7-C

83332:Rv1444c
gene id: 83332:Rv1444c
uniprot id: O06815
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil

83332:Rv1937
gene id: 83332:Rv1937
uniprot id: P95277
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: FAD-binding FR-type

83332:Rv1410c
gene id: 83332:Rv1410c
uniprot id: P9WJY3
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Decreases resistance to ethidium bromide, tested in M.smegmatis.
up seq anno comments: Helical
up seq anno comments: Probable triacylglyceride transporter Rv1410c
up seq anno comments: Susceptible to ethidium bromide, tested in M.smegmatis.
up seq anno feature ids: PRO_0000391006

83332:Rv0406c
gene id: 83332:Rv0406c
uniprot id: O86336
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv1586c
gene id: 83332:Rv1586c
uniprot id: O06604
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Recombinase
up seq anno comments: Resolvase/invertase-type recombinase catalytic

83332:Rv1749c
gene id: 83332:Rv1749c
uniprot id: O65935
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1241
gene id: 83332:Rv1241
uniprot id: O50456
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB33
up seq anno feature ids: PRO_0000408077

83332:Rv2935
gene id: 83332:Rv2935
uniprot id: P9WQE1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acyltransferase
up seq anno comments: Carrier
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: For malonyltransferase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: N-acetylserine
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: Phenolphthiocerol/phthiocerol polyketide synthase subunit E
up seq anno comments: Removed
up seq anno feature ids: PRO_0000406952

83332:Rv2075c
gene id: 83332:Rv2075c
uniprot id: P9WLL5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2075c
up seq anno feature ids: PRO_0000103946

83332:Rv2733c
gene id: 83332:Rv2733c
uniprot id: P9WK05
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: MTTase N-terminal
up seq anno comments: Radical SAM core
up seq anno comments: TRAM
up seq anno comments: tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
up seq anno feature ids: PRO_0000141745

83332:Rv3615c
gene id: 83332:Rv3615c
uniprot id: P9WJD7
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ESX-1 secretion-associated protein EspC
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000104138

83332:Rv3574
gene id: 83332:Rv3574
uniprot id: P96856
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional repressor KstR
up seq anno feature ids: PRO_0000405028

83332:Rv0805
gene id: 83332:Rv0805
uniprot id: P9WP65
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-fold increase in bis(pNPP) hydrolysis. 4-fold decrease in pNPP hydrolysis. 5-fold decrease in 2',3'-cAMP hydrolysis.
up seq anno comments: 25% decrease in bis(pNPP) hydrolysis. 70% decrease in cAMP hydrolysis. Decreases interaction with the cell wall.
up seq anno comments: 40% decrease in bis(pNPP) hydrolysis. 80% decrease in 3',5'-cAMP and 2',3'-cAMP hydrolysis.
up seq anno comments: 40% decrease in bis(pNPP) hydrolysis. Strong decrease in 3',5'-cAMP and 2',3'-cAMP hydrolysis. Abolishes pNPP hydrolysis. Decreases interaction with the cell wall.
up seq anno comments: 50% decrease in bis(pNPP) hydrolysis. Does not affect cAMP hydrolysis. Decreases interaction with the cell wall.
up seq anno comments: 50% decrease in bis(pNPP) hydrolysis. Does not affect cAMP hydrolysis. Strong decrease in interaction with the cell wall.
up seq anno comments: 75% decrease in bis(pNPP) hydrolysis. Does not affect cAMP hydrolysis. Decreases catalytic efficiency and shows lower affinity for both linear and cyclic substrates. Almost completely abrogates interaction with the cell wall in vitro.
up seq anno comments: 8-fold decrease in phosphorylation. Affects localization to the cell wall.
up seq anno comments: 80% decrease in hydrolysis of 3',5'-cAMP and bis(pNPP). 40% decrease in 2',3'-cAMP hydrolysis. Strong decrease in interaction with the cell wall.
up seq anno comments: 90% decrease in bis(pNPP) hydrolysis. Does not affect cAMP hydrolysis. Strong decrease in interaction with the cell wall.
up seq anno comments: C-terminal extension
up seq anno comments: Does not affect localization to the cell wall.
up seq anno comments: Loss of bis(pNPP) and 3',5'-cAMP hydrolysis. Strong decrease in 2',3'-cAMP hydrolysis. Slight decrease in interaction with the cell wall.
up seq anno comments: No change in activity.
up seq anno comments: Phosphothreonine
up seq anno comments: cAMP/cGMP dual specificity phosphodiesterase Rv0805
up seq anno feature ids: PRO_0000413370

83332:Rv2560
gene id: 83332:Rv2560
uniprot id: P9WLA1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized protein Rv2560
up seq anno feature ids: PRO_0000104041

83332:Rv3659c
gene id: 83332:Rv3659c
uniprot id: P9WMT3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative conjugal transfer protein Rv3659c
up seq anno feature ids: PRO_0000390679

83332:Rv3756c
gene id: 83332:Rv3756c
uniprot id: O69722
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv0352
gene id: 83332:Rv0352
uniprot id: P9WNV9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Zinc Finger
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Repeat
up seq anno labels: Sequence Conflict
up seq anno labels: Zinc Finger
up seq anno comments: CR-type
up seq anno comments: CXXCXGXG motif
up seq anno comments: Chaperone protein DnaJ 1
up seq anno comments: J
up seq anno feature ids: PRO_0000070835

83332:Rv0264c
gene id: 83332:Rv0264c
uniprot id: P95221
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxyltransferase

83332:Rv3393
gene id: 83332:Rv3393
uniprot id: O50418
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Inosine/uridine-preferring nucleoside hydrolase

83332:Rv3924c
gene id: 83332:Rv3924c
uniprot id: P9WH93
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL34
up seq anno feature ids: PRO_0000187424

83332:Rv2025c
gene id: 83332:Rv2025c
uniprot id: P9WGF5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable cation efflux system protein Rv2025c
up seq anno feature ids: PRO_0000419181

83332:Rv3579c
gene id: 83332:Rv3579c
uniprot id: P9WFY5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized tRNA/rRNA methyltransferase Rv3579c
up seq anno feature ids: PRO_0000379581

83332:Rv0091
gene id: 83332:Rv0091
uniprot id: P9WJM3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000164446

83332:Rv0186A
gene id: 83332:Rv0186A
uniprot id: P9WK09
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Propeptide
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mass
up seq anno labels: Propeptide
up seq anno comments: Metallothionein
up seq anno feature ids: PRO_0000401202
up seq anno feature ids: PRO_0000401203

83332:Rv0926c
gene id: 83332:Rv0926c
uniprot id: I6WZS8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 2,4-diaminopentanoate dehydrogenase C-terminal

83332:Rv3870
gene id: 83332:Rv3870
uniprot id: P9WNB3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Cells unable to export EsxB, missing transmembrane domain.
up seq anno comments: Cells unable to export EsxB.
up seq anno comments: Decreased export of EsxB.
up seq anno comments: ESX-1 secretion system protein EccCa1
up seq anno comments: FtsK
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393428

83332:Rv0749
gene id: 83332:Rv0749
uniprot id: P9WF75
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC31
up seq anno feature ids: PRO_0000407888

83332:Rv2955c
gene id: 83332:Rv2955c
uniprot id: P95137
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase FkbM

83332:Rv1596
gene id: 83332:Rv1596
uniprot id: P9WJJ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Nicotinate-nucleotide pyrophosphorylase [carboxylating]
up seq anno feature ids: PRO_0000155946

83332:Rv0616A
gene id: 83332:Rv0616A
uniprot id: P9WJ37
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB29
up seq anno feature ids: PRO_0000408073

83332:Rv3294c
gene id: 83332:Rv3294c
uniprot id: L7N658
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF4143

83332:Rv3020c
gene id: 83332:Rv3020c
uniprot id: Q6MX18
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: ESAT-6-like protein EsxS
up seq anno feature ids: PRO_0000436932

83332:Rv2787
gene id: 83332:Rv2787
uniprot id: O33329
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CobQ/CobB/MinD/ParA nucleotide binding
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1424c
gene id: 83332:Rv1424c
uniprot id: P9WLX7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1424c
up seq anno feature ids: PRO_0000103847

83332:Rv0895
gene id: 83332:Rv0895
uniprot id: P9WKA3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv0895
up seq anno feature ids: PRO_0000222906

83332:Rv2603c
gene id: 83332:Rv2603c
uniprot id: P9WGA5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable transcriptional regulatory protein Rv2603c
up seq anno feature ids: PRO_0000175853

83332:Rv2246
gene id: 83332:Rv2246
uniprot id: P9WQD7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-oxoacyl-[acyl-carrier-protein] synthase 2
up seq anno comments: Decreases phosphorylation. Lack of phosphorylation; when associated with A-313.
up seq anno comments: Decreases phosphorylation. Lack of phosphorylation; when associated with A-315.
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Phosphomimetic mutant. Loss of acid-fast staining and reduced pathogenicity; when associated with D-313.
up seq anno comments: Phosphomimetic mutant. Loss of acid-fast staining and reduced pathogenicity; when associated with D-315.
up seq anno comments: Phosphothreonine
up seq anno feature ids: PRO_0000180334

83332:Rv3071
gene id: 83332:Rv3071
uniprot id: P95087
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0328
gene id: 83332:Rv0328
uniprot id: O07252
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1711
gene id: 83332:Rv1711
uniprot id: P9WHQ1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Nucleophile
up seq anno comments: S4 RNA-binding
up seq anno comments: Uncharacterized RNA pseudouridine synthase Rv1711
up seq anno feature ids: PRO_0000100029

83332:Rv3258c
gene id: 83332:Rv3258c
uniprot id: O53351
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2906c
gene id: 83332:Rv2906c
uniprot id: P9WFY7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: tRNA (guanine-N(1)-)-methyltransferase
up seq anno feature ids: PRO_0000060410

83332:Rv1541c
gene id: 83332:Rv1541c
uniprot id: P9WK41
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno comments: Decreased apparent weight in M.smegmatis, a portion of the protein is protected from extracellular trypsin.
up seq anno comments: Lipoprotein LprI
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018150

83332:Rv3766
gene id: 83332:Rv3766
uniprot id: O69731
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3766
up seq anno feature ids: PRO_0000432523

83332:Rv2723
gene id: 83332:Rv2723
uniprot id: P9WG93
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein Rv2723
up seq anno feature ids: PRO_0000103421

83332:Rv1833c
gene id: 83332:Rv1833c
uniprot id: P9WMS1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1
up seq anno comments: Haloalkane dehalogenase 2
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000216769

83332:Rv3041c
gene id: 83332:Rv3041c
uniprot id: I6YF11
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv3591c
gene id: 83332:Rv3591c
uniprot id: I6YGL1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv2550c
gene id: 83332:Rv2550c
uniprot id: P9WJ45
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB20
up seq anno feature ids: PRO_0000408066

83332:Rv0446c
gene id: 83332:Rv0446c
uniprot id: O53731
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Steroid 5-alpha reductase C-terminal

83332:Rv0035
gene id: 83332:Rv0035
uniprot id: L7N699
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: AMP-dependent synthetase/ligase
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv2488c
gene id: 83332:Rv2488c
uniprot id: O53213
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno comments: Guanylate cyclase
up seq anno comments: HTH luxR-type

83332:Rv3477
gene id: 83332:Rv3477
uniprot id: I6YG87
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv0591
gene id: 83332:Rv0591
uniprot id: O07787
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv1456c
gene id: 83332:Rv1456c
uniprot id: O53148
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0232
gene id: 83332:Rv0232
uniprot id: P96415
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1420
gene id: 83332:Rv1420
uniprot id: P9WFC5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: GIY-YIG
up seq anno comments: UVR
up seq anno comments: UvrABC system protein C
up seq anno feature ids: PRO_0000138320

83332:Rv3713
gene id: 83332:Rv3713
uniprot id: I6XI14
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: CobB/CobQ-like glutamine amidotransferase
up seq anno comments: Nucleophile

83332:Rv2128
gene id: 83332:Rv2128
uniprot id: O33262
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0905
gene id: 83332:Rv0905
uniprot id: P9WNP1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable enoyl-CoA hydratase EchA6
up seq anno feature ids: PRO_0000109335

83332:Rv1252c
gene id: 83332:Rv1252c
uniprot id: P9WK49
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Putative lipoprotein LprE
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018141

83332:Rv2085
gene id: 83332:Rv2085
uniprot id: P9WLJ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2085
up seq anno feature ids: PRO_0000103956

83332:Rv2434c
gene id: 83332:Rv2434c
uniprot id: P71915
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Cyclic nucleotide-binding
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2745c
gene id: 83332:Rv2745c
uniprot id: P9WMH7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: Transcriptional regulator ClgR
up seq anno feature ids: PRO_0000423653

83332:Rv3627c
gene id: 83332:Rv3627c
uniprot id: O06380
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Carboxypeptidase Rv3627c
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_5004156985

83332:Rv0816c
gene id: 83332:Rv0816c
uniprot id: I6Y8V2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thioredoxin

83332:Rv2572c
gene id: 83332:Rv2572c
uniprot id: P9WFW3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Aspartate
up seq anno comments: Aspartate--tRNA(Asp/Asn) ligase
up seq anno comments: Disordered
up seq anno comments: Important for tRNA non-discrimination
up seq anno feature ids: PRO_0000110908

83332:Rv2035
gene id: 83332:Rv2035
uniprot id: O53479
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Activator of Hsp90 ATPase homologue 1-like C-terminal

83332:Rv0500A
gene id: 83332:Rv0500A
uniprot id: P9WKT7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno comments: H-T-H motif
up seq anno comments: Putative DNA-binding protein Rv0500A
up seq anno feature ids: PRO_0000399397

83332:Rv0643c
gene id: 83332:Rv0643c
uniprot id: P0CH91
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Loss of O-methyltransferase activity.
up seq anno comments: Methoxy mycolic acid synthase MmaA3
up seq anno feature ids: PRO_0000398362

83332:Rv1466
gene id: 83332:Rv1466
uniprot id: O53157
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MIP18 family-like

83332:Rv0940c
gene id: 83332:Rv0940c
uniprot id: P9WKP1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0940c
up seq anno feature ids: PRO_0000103743

83332:Rv2695
gene id: 83332:Rv2695
uniprot id: I6Y1I1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv3883c
gene id: 83332:Rv3883c
uniprot id: O05461
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Charge relay system
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Lack of protease activity. Has hyperactivated ESX-1 secretion during macrophage infection, resulting in increased innate immune signaling. Secretes full-length EspB.
up seq anno comments: Mycosin-1
up seq anno comments: Peptidase S8
up seq anno feature ids: PRO_5007696644

83332:Rv1128c
gene id: 83332:Rv1128c
uniprot id: P9WM57
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1128c
up seq anno feature ids: PRO_0000103769

83332:Rv1607
gene id: 83332:Rv1607
uniprot id: O53910
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Sodium/calcium exchanger membrane region

83332:Rv1783
gene id: 83332:Rv1783
uniprot id: P9WNA5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: ESX-5 secretion system protein EccC5
up seq anno comments: FtsK 1
up seq anno comments: FtsK 2
up seq anno comments: FtsK 3
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393433

83332:Rv1435c
gene id: 83332:Rv1435c
uniprot id: O06823
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno feature ids: PRO_5004156960

83332:Rv2264c
gene id: 83332:Rv2264c
uniprot id: O53538
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv1372
gene id: 83332:Rv1372
uniprot id: P9WPF1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alpha-pyrone synthesis polyketide synthase-like Pks18
up seq anno comments: Cannot be recovered in the soluble form.
up seq anno comments: Completely abolishes the polyketide synthase activity with lauroyl-CoA and palmitoyl-CoA.
up seq anno comments: Disordered
up seq anno comments: Efficiently catalyzed the synthesis of the triketide pyrone of the C6 starter unit and shows weak polyketide synthase activity with the C12 starter molecule.
up seq anno comments: Important for broad specificity for aliphatic long-chain acyl-CoA starter units
up seq anno comments: Increase in the synthesis of the tetraketide products.
up seq anno comments: Loss of polyketide synthase activity.
up seq anno comments: No significant change in polyketide synthase activity.
up seq anno comments: Nucleophile
up seq anno comments: Retained reasonable polyketide synthase activity with lauroyl-CoA but cannot use palmitoyl-CoA.
up seq anno comments: Unable to synthesize any polyketide products.
up seq anno feature ids: PRO_0000407320

83332:Rv3082c
gene id: 83332:Rv3082c
uniprot id: P9WMJ3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno comments: H-T-H motif
up seq anno comments: HTH araC/xylS-type
up seq anno comments: HTH-type transcriptional regulator VirS
up seq anno feature ids: PRO_0000194592

83332:Rv0339c
gene id: 83332:Rv0339c
uniprot id: O33269
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HTH luxR-type

83332:Rv1722
gene id: 83332:Rv1722
uniprot id: P71980
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ATP-grasp

83332:Rv2090
gene id: 83332:Rv2090
uniprot id: P9WNU3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 5'-3' exonuclease
up seq anno feature ids: PRO_0000101290

83332:Rv3270
gene id: 83332:Rv3270
uniprot id: P9WPT5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: HMA
up seq anno comments: Helical
up seq anno comments: Loss of ATPase activity.
up seq anno comments: Manganese-exporting P-type ATPase
up seq anno feature ids: PRO_0000046337

83332:Rv2917
gene id: 83332:Rv2917
uniprot id: P9WL21
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helicase ATP-binding
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized protein Rv2917
up seq anno feature ids: PRO_0000104102

83332:Rv1553
gene id: 83332:Rv1553
uniprot id: P9WN89
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: 4Fe-4S ferredoxin-type
up seq anno comments: Fumarate reductase iron-sulfur subunit
up seq anno feature ids: PRO_0000158705

83332:Rv3776
gene id: 83332:Rv3776
uniprot id: P72042
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv3776
up seq anno feature ids: PRO_0000405540

83332:Rv3086
gene id: 83332:Rv3086
uniprot id: P9WQB9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative alcohol dehydrogenase D
up seq anno feature ids: PRO_0000420879

83332:Rv3803c
gene id: 83332:Rv3803c
uniprot id: P9WQN7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: MPT51/MPB51 antigen
up seq anno feature ids: PRO_0000000230

83332:Rv3052c
gene id: 83332:Rv3052c
uniprot id: P9WIZ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein NrdI
up seq anno feature ids: PRO_0000164327

83332:Rv3604c
gene id: 83332:Rv3604c
uniprot id: O06278
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: DUF6779
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Pro residues

83332:Rv0458
gene id: 83332:Rv0458
uniprot id: P9WNY1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Probable aldehyde dehydrogenase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000056449

83332:Rv0438c
gene id: 83332:Rv0438c
uniprot id: P9WJQ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Molybdopterin molybdenumtransferase 2
up seq anno feature ids: PRO_0000170992

83332:Rv0151c
gene id: 83332:Rv0151c
uniprot id: Q79G06
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: PE
up seq anno comments: PE-PPE

83332:Rv2499c
gene id: 83332:Rv2499c
uniprot id: I6Y9H2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MaoC-like

83332:Rv3533c
gene id: 83332:Rv3533c
uniprot id: P9WHX7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized PPE family protein PPE62
up seq anno feature ids: PRO_0000379117

83332:Rv3895c
gene id: 83332:Rv3895c
uniprot id: P9WNR5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-2 secretion system ATPase EccB2
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393229

83332:Rv0283
gene id: 83332:Rv0283
uniprot id: P9WNR3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: ESX-3 secretion system ATPase EccB3
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393230

83332:Rv0601c
gene id: 83332:Rv0601c
uniprot id: O07777
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase; first part
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Sensor histidine kinase component HK2
up seq anno feature ids: PRO_0000391080

83332:Rv1959c
gene id: 83332:Rv1959c
uniprot id: P9WHG7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Toxin ParE1
up seq anno feature ids: PRO_0000408372

83332:Rv3723
gene id: 83332:Rv3723
uniprot id: O69690
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Acidic residues
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Lipid uptake coordinator A
up seq anno feature ids: PRO_0000441801

83332:Rv0956
gene id: 83332:Rv0956
uniprot id: P9WHM5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Phosphoribosylglycinamide formyltransferase
up seq anno comments: Proton donor
up seq anno comments: Raises pKa of active site His
up seq anno feature ids: PRO_0000420698

83332:Rv0426c
gene id: 83332:Rv0426c
uniprot id: P96272
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv2138
gene id: 83332:Rv2138
uniprot id: O06237
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno feature ids: PRO_5038892344

83332:Rv0917
gene id: 83332:Rv0917
uniprot id: P9WPR7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized transporter Rv0917
up seq anno feature ids: PRO_0000201497

83332:Rv1777
gene id: 83332:Rv1777
uniprot id: P9WPL1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cytochrome P450 144
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052307

83332:Rv2616
gene id: 83332:Rv2616
uniprot id: O06198
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF1990

83332:Rv1257c
gene id: 83332:Rv1257c
uniprot id: Q11061
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv2444c
gene id: 83332:Rv2444c
uniprot id: P71905
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Acidic residues
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Ribonuclease E
up seq anno comments: S1 motif
up seq anno feature ids: PRO_0000458842

83332:Rv3280
gene id: 83332:Rv3280
uniprot id: P9WQH7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta5 subunit
up seq anno comments: CoA carboxyltransferase C-terminal
up seq anno comments: CoA carboxyltransferase N-terminal
up seq anno comments: Disordered
up seq anno comments: Removed
up seq anno feature ids: PRO_0000199799

83332:Rv0549c
gene id: 83332:Rv0549c
uniprot id: P9WFB7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC3
up seq anno feature ids: PRO_0000407866

83332:Rv2756c
gene id: 83332:Rv2756c
uniprot id: O33298
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DNA methylase adenine-specific
up seq anno comments: N6 adenine-specific DNA methyltransferase N-terminal

83332:Rv2251
gene id: 83332:Rv2251
uniprot id: L0TBR2
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: FAD-binding PCMH-type
up seq anno comments: Important for enzyme activity
up seq anno comments: Proton donor/acceptor

83332:Rv3096
gene id: 83332:Rv3096
uniprot id: I6YB54
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: 1,4-beta-xylanase
up seq anno feature ids: PRO_5010248535

83332:Rv2583c
gene id: 83332:Rv2583c
uniprot id: P9WHG9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: ACT
up seq anno comments: Altered association with RAC components.
up seq anno comments: Bifunctional (p)ppGpp synthase/hydrolase RelA
up seq anno comments: Disordered
up seq anno comments: HD
up seq anno comments: Loss of hydrolytic activity.
up seq anno comments: Loss of ppGpp synthase activity.
up seq anno comments: Nucleophile, for hydrolase activity
up seq anno comments: TGS
up seq anno feature ids: PRO_0000166551

83332:Rv1228
gene id: 83332:Rv1228
uniprot id: O33224
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5039382289

83332:Rv2045c
gene id: 83332:Rv2045c
uniprot id: O53488
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxylesterase type B

83332:Rv0119
gene id: 83332:Rv0119
uniprot id: O07169
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv0952
gene id: 83332:Rv0952
uniprot id: P9WGC7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Succinate--CoA ligase [ADP-forming] subunit alpha
up seq anno comments: Tele-phosphohistidine intermediate
up seq anno feature ids: PRO_0000102796

83332:Rv1478
gene id: 83332:Rv1478
uniprot id: P9WHU5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes host cell invasion.
up seq anno comments: NlpC/P60
up seq anno comments: Nucleophile
up seq anno comments: Peptidoglycan endopeptidase RipB
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000413763

83332:Rv0772
gene id: 83332:Rv0772
uniprot id: P9WHM9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ATP-grasp
up seq anno comments: Phosphoribosylamine--glycine ligase
up seq anno feature ids: PRO_0000151464

83332:Rv1788
gene id: 83332:Rv1788
uniprot id: L7N649
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv0436c
gene id: 83332:Rv0436c
uniprot id: P9WPG1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: CDP-diacylglycerol--serine O-phosphatidyltransferase
up seq anno comments: Helical
up seq anno feature ids: PRO_0000056798

83332:Rv1617
gene id: 83332:Rv1617
uniprot id: P9WKE5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Partial loss of phosphorylation. Decrease in activity.
up seq anno comments: Phosphoserine; by PknJ; in vitro
up seq anno comments: Pyruvate kinase
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000112082

83332:Rv3376
gene id: 83332:Rv3376
uniprot id: P9WMS5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: Phosphatase Rv3376
up seq anno feature ids: PRO_0000416458

83332:Rv0162c
gene id: 83332:Rv0162c
uniprot id: L7N6B3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Enoyl reductase (ER)

83332:Rv0238
gene id: 83332:Rv0238
uniprot id: O53661
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1446c
gene id: 83332:Rv1446c
uniprot id: O06813
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
up seq anno comments: Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal

83332:Rv2274c
gene id: 83332:Rv2274c
uniprot id: P9WIH7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative toxin MazF8
up seq anno feature ids: PRO_0000104003

83332:Rv1452c
gene id: 83332:Rv1452c
uniprot id: Q79FP1
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv3649
gene id: 83332:Rv3649
uniprot id: O06359
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal

83332:Rv0350
gene id: 83332:Rv0350
uniprot id: P9WMJ9
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Chaperone protein DnaK
up seq anno comments: Disordered
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno feature ids: PRO_0000078499

83332:Rv1732c
gene id: 83332:Rv1732c
uniprot id: P71990
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thioredoxin

83332:Rv2102
gene id: 83332:Rv2102
uniprot id: O53500
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Zinc Finger
up seq anno labels: Chain
up seq anno labels: Zinc Finger
up seq anno comments: SWIM-type
up seq anno comments: Uncharacterized protein Rv2102
up seq anno feature ids: PRO_0000432518

83332:Rv2927c
gene id: 83332:Rv2927c
uniprot id: P9WL15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2927c
up seq anno feature ids: PRO_0000104109

83332:Rv1566c
gene id: 83332:Rv1566c
uniprot id: O06624
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: NlpC/P60
up seq anno comments: Polar residues
up seq anno feature ids: PRO_5039110663

83332:Rv3788
gene id: 83332:Rv3788
uniprot id: P9WKW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3788
up seq anno feature ids: PRO_0000104150

83332:Rv3915
gene id: 83332:Rv3915
uniprot id: L7N653
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: MurNAc-LAA
up seq anno comments: N-acetylmuramoyl-L-alanine amidase CwlM
up seq anno comments: Peptidoglycan-binding domain 1
up seq anno comments: Peptidoglycan-binding domain 2
up seq anno feature ids: PRO_0000434795

83332:Rv2404c
gene id: 83332:Rv2404c
uniprot id: P9WK97
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Elongation factor 4
up seq anno comments: tr-type G
up seq anno feature ids: PRO_0000176307

83332:Rv3617
gene id: 83332:Rv3617
uniprot id: I6YGS0
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: AB hydrolase-1
up seq anno comments: Contributes to the formation of an oxyanion binding site for the epoxide oxygen of substrate
up seq anno comments: Epoxide hydrolase A
up seq anno comments: Nucleophile
up seq anno comments: Plays an orienting role for the imidazole group of His-298
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000438585

83332:Rv2222c
gene id: 83332:Rv2222c
uniprot id: P9WN37
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: GS beta-grasp
up seq anno comments: GS catalytic
up seq anno comments: Glutamine synthetase
up seq anno comments: Important for inhibition by glutamine
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno feature ids: PRO_0000153247

83332:Rv3409c
gene id: 83332:Rv3409c
uniprot id: P9WMV9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Cholesterol oxidase
up seq anno comments: Disordered
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000405326

83332:Rv0295c
gene id: 83332:Rv0295c
uniprot id: O53699
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Trehalose 2-sulfotransferase
up seq anno feature ids: PRO_0000434782

83332:Rv3596c
gene id: 83332:Rv3596c
uniprot id: P9WPC9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-dependent Clp protease ATP-binding subunit ClpC1
up seq anno comments: Clp R
up seq anno comments: Disordered
up seq anno comments: I
up seq anno comments: II
up seq anno comments: Repeat 1
up seq anno comments: Repeat 2
up seq anno comments: UVR
up seq anno feature ids: PRO_0000191236

83332:Rv3905c
gene id: 83332:Rv3905c
uniprot id: P9WNH7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxF
up seq anno feature ids: PRO_0000167820

83332:Rv1152
gene id: 83332:Rv1152
uniprot id: O06550
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH gntR-type

83332:Rv3734c
gene id: 83332:Rv3734c
uniprot id: P9WKC7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Probable diacyglycerol O-acyltransferase tgs2
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000222921

83332:Rv0966c
gene id: 83332:Rv0966c
uniprot id: P9WKM1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0966c
up seq anno feature ids: PRO_0000103764

83332:Rv2237A
gene id: 83332:Rv2237A
uniprot id: I6XDU8
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1805c
gene id: 83332:Rv1805c
uniprot id: O53954
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2626c
gene id: 83332:Rv2626c
uniprot id: P9WJA3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: Forms less stable dimer.
up seq anno comments: Hypoxic response protein 1
up seq anno comments: Interchain
up seq anno comments: No longer forms SDS-resistant dimer.
up seq anno feature ids: PRO_0000392622

83332:Rv1267c
gene id: 83332:Rv1267c
uniprot id: P9WGJ9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolished phosphorylation.
up seq anno comments: Decreases phosphorylation by PknH.
up seq anno comments: FHA
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Transcriptional regulatory protein EmbR
up seq anno feature ids: PRO_0000110008

83332:Rv1621c
gene id: 83332:Rv1621c
uniprot id: O06138
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Helical

83332:Rv2802c
gene id: 83332:Rv2802c
uniprot id: P71649
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF2293

83332:Rv2454c
gene id: 83332:Rv2454c
uniprot id: O53181
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: 2-oxoglutarate oxidoreductase subunit KorB
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000420517

83332:Rv1588c
gene id: 83332:Rv1588c
uniprot id: P9WLT9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1588c
up seq anno feature ids: PRO_0000103886

83332:Rv3290c
gene id: 83332:Rv3290c
uniprot id: P9WQ77
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable L-lysine-epsilon aminotransferase
up seq anno feature ids: PRO_0000120512

83332:Rv0560c
gene id: 83332:Rv0560c
uniprot id: P9WKL5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase
up seq anno comments: 6.7-fold increase in catalytic efficiency with componud 14 as substrate.
up seq anno feature ids: PRO_0000419777

83332:Rv2767c
gene id: 83332:Rv2767c
uniprot id: O33309
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1096
gene id: 83332:Rv1096
uniprot id: O53444
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: NodB homology
up seq anno comments: Polar residues

83332:Rv3107c
gene id: 83332:Rv3107c
uniprot id: O05784
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: FAD-binding PCMH-type
up seq anno comments: Important for enzyme activity
up seq anno comments: Proton donor/acceptor

83332:Rv2594c
gene id: 83332:Rv2594c
uniprot id: P9WGV9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Crossover junction endodeoxyribonuclease RuvC
up seq anno feature ids: PRO_0000183110

83332:Rv1238
gene id: 83332:Rv1238
uniprot id: P9WQI3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno comments: ABC transporter
up seq anno comments: Decreased hydrolysis of ATP. No change in KM, but 2-fold reduction in Vmax compared to wild-type.
up seq anno comments: Helical C-loop; LSGGQ motif
up seq anno comments: Trehalose import ATP-binding protein SugC
up seq anno feature ids: PRO_0000419314

83332:Rv0746
gene id: 83332:Rv0746
uniprot id: Q79FW8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3419c
gene id: 83332:Rv3419c
uniprot id: P9WHT7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: tRNA N6-adenosine threonylcarbamoyltransferase
up seq anno feature ids: PRO_0000096970

83332:Rv0659c
gene id: 83332:Rv0659c
uniprot id: P9WII1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable endoribonuclease MazF2
up seq anno feature ids: PRO_0000406305

83332:Rv3792
gene id: 83332:Rv3792
uniprot id: P9WN03
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Extracellular
up seq anno comments: Galactan 5-O-arabinofuranosyltransferase
up seq anno comments: Helical
up seq anno feature ids: PRO_0000250356

83332:Rv0131c
gene id: 83332:Rv0131c
uniprot id: P96808
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv0625c
gene id: 83332:Rv0625c
uniprot id: P9WFS5
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: TVP38/TMEM64 family membrane protein Rv0625c
up seq anno feature ids: PRO_0000198636

83332:Rv3758c
gene id: 83332:Rv3758c
uniprot id: O69724
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv1490
gene id: 83332:Rv1490
uniprot id: P9WLX1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1490
up seq anno feature ids: PRO_0000103856

83332:Rv3239c
gene id: 83332:Rv3239c
uniprot id: O05884
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Transmembrane
up seq anno comments: Cyclic nucleotide-binding
up seq anno comments: DGA/G
up seq anno comments: GXGXXG
up seq anno comments: GXSXG
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor

83332:Rv2715
gene id: 83332:Rv2715
uniprot id: P9WNH3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2715
up seq anno feature ids: PRO_0000207084

83332:Rv1808
gene id: 83332:Rv1808
uniprot id: P9WI05
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE32
up seq anno feature ids: PRO_0000379112

83332:Rv1628c
gene id: 83332:Rv1628c
uniprot id: O06145
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF35

83332:Rv3390
gene id: 83332:Rv3390
uniprot id: O50416
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5039483851

83332:Rv2149c
gene id: 83332:Rv2149c
uniprot id: P9WKD5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Purine nucleoside phosphorylase Rv2149c
up seq anno feature ids: PRO_0000163166

83332:Rv0275c
gene id: 83332:Rv0275c
uniprot id: L7N6A2
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv0248c
gene id: 83332:Rv0248c
uniprot id: O53670
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: FAD-dependent oxidoreductase 2 FAD binding
up seq anno comments: Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
up seq anno comments: Proton acceptor

83332:Rv2816c
gene id: 83332:Rv2816c
uniprot id: P9WPJ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: CRISPR-associated endoribonuclease Cas2
up seq anno feature ids: PRO_0000418219

83332:Rv1548c
gene id: 83332:Rv1548c
uniprot id: P9WI21
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized PPE family protein PPE21
up seq anno feature ids: PRO_0000217846

83332:Rv0078
gene id: 83332:Rv0078
uniprot id: O53623
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv2287
gene id: 83332:Rv2287
uniprot id: P9WJI3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized Na(+)/H(+) exchanger Rv2287
up seq anno feature ids: PRO_0000052400

83332:Rv0922
gene id: 83332:Rv0922
uniprot id: I6Y560
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Probable transposase IS891/IS1136/IS1341

83332:Rv0570
gene id: 83332:Rv0570
uniprot id: P9WH77
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno comments: ATP-cone
up seq anno comments: Cysteine radical intermediate
up seq anno comments: Proton acceptor
up seq anno comments: Redox-active
up seq anno comments: Vitamin B12-dependent ribonucleoside-diphosphate reductase
up seq anno feature ids: PRO_0000392684

83332:Rv3663c
gene id: 83332:Rv3663c
uniprot id: I6Y482
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv2116
gene id: 83332:Rv2116
uniprot id: P9WK75
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppK
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018111

83332:Rv1578c
gene id: 83332:Rv1578c
uniprot id: O06612
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2415c
gene id: 83332:Rv2415c
uniprot id: P71728
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Helix-hairpin-helix DNA-binding motif class 1
up seq anno comments: Polar residues

83332:Rv0481c
gene id: 83332:Rv0481c
uniprot id: P9WKV5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0481c
up seq anno feature ids: PRO_0000103683

83332:Rv2232
gene id: 83332:Rv2232
uniprot id: P9WPI9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decreases affinity for ATP and autophosphorylation efficiency.
up seq anno comments: Decreases affinity for ATP and autophosphorylation efficiency. Decreases interaction with PtpA.
up seq anno comments: Disordered
up seq anno comments: Does not affect autophosphorylation.
up seq anno comments: Lack of autophosphorylation. Decreases interaction with PtpA. Cannot phosphorylate and activate PtpA.
up seq anno comments: Phosphotyrosine; by autocatalysis
up seq anno comments: Polar residues
up seq anno comments: Significant decrease in ATP binding affinity and autophosphorylation efficiency. Decreases interaction with PtpA.
up seq anno comments: Tyrosine-protein kinase PtkA
up seq anno feature ids: PRO_0000108066

83332:Rv3068c
gene id: 83332:Rv3068c
uniprot id: I6Y2G3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alpha-D-phosphohexomutase C-terminal
up seq anno comments: Alpha-D-phosphohexomutase alpha/beta/alpha

83332:Rv2725c
gene id: 83332:Rv2725c
uniprot id: O33230
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Hflx-type G

83332:Rv0309
gene id: 83332:Rv0309
uniprot id: O07236
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5039359811

83332:Rv3917c
gene id: 83332:Rv3917c
uniprot id: P9WIJ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Probable chromosome-partitioning protein ParB
up seq anno feature ids: PRO_0000178685

83332:Rv1162
gene id: 83332:Rv1162
uniprot id: O06560
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 4Fe-4S ferredoxin-type

83332:Rv2903c
gene id: 83332:Rv2903c
uniprot id: P9WKA1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Signal peptidase I
up seq anno feature ids: PRO_0000109511

83332:Rv2548A
gene id: 83332:Rv2548A
uniprot id: I6XEK2
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil

83332:Rv1820
gene id: 83332:Rv1820
uniprot id: P9WG39
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acetolactate synthase large subunit IlvG
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: Thiamine pyrophosphate binding
up seq anno feature ids: PRO_0000090805

83332:Rv1458c
gene id: 83332:Rv1458c
uniprot id: O53149
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv2637
gene id: 83332:Rv2637
uniprot id: P9WP07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein Rv2637
up seq anno feature ids: PRO_0000161430

83332:Rv1705c
gene id: 83332:Rv1705c
uniprot id: P9WI19
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE22
up seq anno feature ids: PRO_0000378478

83332:Rv1277
gene id: 83332:Rv1277
uniprot id: Q50699
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Calcineurin-like phosphoesterase

83332:Rv1632c
gene id: 83332:Rv1632c
uniprot id: O06149
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF402

83332:Rv2466c
gene id: 83332:Rv2466c
uniprot id: O53193
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: Lack of activity. Confers resistance to TP053.
up seq anno comments: Thioredoxin-like reductase Rv2466c
up seq anno feature ids: PRO_0000433023

83332:Rv3302c
gene id: 83332:Rv3302c
uniprot id: P9WN79
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glycerol-3-phosphate dehydrogenase 2
up seq anno feature ids: PRO_0000126102

83332:Rv1108c
gene id: 83332:Rv1108c
uniprot id: P9WF31
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Exodeoxyribonuclease 7 large subunit
up seq anno feature ids: PRO_0000197860

83332:Rv1934c
gene id: 83332:Rv1934c
uniprot id: P95280
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative acyl-CoA dehydrogenase FadE17
up seq anno feature ids: PRO_0000438538

83332:Rv3124
gene id: 83332:Rv3124
uniprot id: O05797
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Mutagenesis Site
up seq anno comments: Completely disrupts protein function, as shown by the dramatic decrease of RNA levels for the moa1 locus.
up seq anno comments: Has no deleterious effect on the transcription of the moa1 locus.
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Shows reduced transcription of the moa1 locus.
up seq anno comments: Shows significantly reduced transcription of the moa1 locus.
up seq anno comments: Transcriptional regulatory protein MoaR1
up seq anno feature ids: PRO_0000415513

83332:Rv0002
gene id: 83332:Rv0002
uniprot id: P9WNU1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Beta sliding clamp
up seq anno feature ids: PRO_0000105451

83332:Rv0832
gene id: 83332:Rv0832
uniprot id: Q79FV8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv2932
gene id: 83332:Rv2932
uniprot id: P9WQE5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acyltransferase
up seq anno comments: Beta-ketoacyl reductase
up seq anno comments: Carrier
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: For malonyltransferase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: Phenolphthiocerol/phthiocerol polyketide synthase subunit B
up seq anno feature ids: PRO_0000180302

83332:Rv3433c
gene id: 83332:Rv3433c
uniprot id: P9WF11
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ADP-dependent (S)-NAD(P)H-hydrate dehydratase
up seq anno comments: Bifunctional NAD(P)H-hydrate repair enzyme Nnr
up seq anno comments: NAD(P)H-hydrate epimerase
up seq anno comments: NADPHX 1; for epimerase activity
up seq anno comments: NADPHX 2; for dehydratase activity
up seq anno comments: YjeF C-terminal
up seq anno comments: YjeF N-terminal
up seq anno feature ids: PRO_0000119048

83332:Rv0141c
gene id: 83332:Rv0141c
uniprot id: P96818
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv3804c
gene id: 83332:Rv3804c
uniprot id: P9WQP3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes diacylglycerol acyltransferase activity.
up seq anno comments: Diacylglycerol acyltransferase/mycolyltransferase Ag85A
up seq anno comments: Fibronectin-binding
up seq anno comments: Nucleophile
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000000214

83332:Rv0669c
gene id: 83332:Rv0669c
uniprot id: O06769
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Neutral ceramidase
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000420250

83332:Rv1904
gene id: 83332:Rv1904
uniprot id: O07728
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: STAS

83332:Rv3250c
gene id: 83332:Rv3250c
uniprot id: I6YFL7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rubredoxin-like

83332:Rv1981c
gene id: 83332:Rv1981c
uniprot id: P9WH73
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: Ribonucleoside-diphosphate reductase subunit beta nrdF1
up seq anno feature ids: PRO_0000190486

83332:Rv1330c
gene id: 83332:Rv1330c
uniprot id: P9WJI9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Nicotinate phosphoribosyltransferase pncB1
up seq anno comments: Phosphohistidine
up seq anno feature ids: PRO_0000103804

83332:Rv3401
gene id: 83332:Rv3401
uniprot id: P9WN13
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Proton donor
up seq anno comments: Uncharacterized glycosyl hydrolase Rv3401
up seq anno feature ids: PRO_0000108021

83332:Rv1297
gene id: 83332:Rv1297
uniprot id: P9WHF3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Rho RNA-BD
up seq anno comments: Transcription termination factor Rho
up seq anno feature ids: PRO_0000188970

83332:Rv0318c
gene id: 83332:Rv0318c
uniprot id: Q6MX47
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2159c
gene id: 83332:Rv2159c
uniprot id: O06218
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Abolishes interaction with PknI.
up seq anno comments: Alkyl hydroperoxide reductase Rv2159c
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: Does not affect interaction with PknI.
up seq anno comments: Important for interaction with PknI
up seq anno comments: Loss of activity.
up seq anno comments: No change in activity.
up seq anno feature ids: PRO_0000458113

83332:Rv0789c
gene id: 83332:Rv0789c
uniprot id: I6Y4U0
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv3921c
gene id: 83332:Rv3921c
uniprot id: P9WIT5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Membrane protein insertase YidC
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000124730

83332:Rv0261c
gene id: 83332:Rv0261c
uniprot id: P95218
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1130
gene id: 83332:Rv1130
uniprot id: O06582
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: 2-methylcitrate dehydratase
up seq anno feature ids: PRO_0000432935

83332:Rv0617
gene id: 83332:Rv0617
uniprot id: P9WF79
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC29
up seq anno feature ids: PRO_0000407887

83332:Rv0088
gene id: 83332:Rv0088
uniprot id: P9WM73
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0088
up seq anno feature ids: PRO_0000103662

83332:Rv2297
gene id: 83332:Rv2297
uniprot id: P9WLD9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv2297
up seq anno feature ids: PRO_0000014131

83332:Rv0937c
gene id: 83332:Rv0937c
uniprot id: P9WKD9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Ku
up seq anno comments: Non-homologous end joining protein Ku
up seq anno comments: Sufficient for interaction with LigD
up seq anno feature ids: PRO_0000425945

83332:Rv0581
gene id: 83332:Rv0581
uniprot id: O53778
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Antitoxin VapB26
up seq anno feature ids: PRO_0000408071

83332:Rv0078B
gene id: 83332:Rv0078B
uniprot id: I6X8G2
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2130c
gene id: 83332:Rv2130c
uniprot id: P9WJM9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: 'ERGGDP' region
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
up seq anno feature ids: PRO_0000159442

83332:Rv0758
gene id: 83332:Rv0758
uniprot id: P71815
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase

83332:Rv1249c
gene id: 83332:Rv1249c
uniprot id: O50464
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2942
gene id: 83332:Rv2942
uniprot id: P9WJU7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Leads to decreased interaction with PpsE, but does not decrease MmpL7 activity in vivo.
up seq anno comments: Phthiocerol dimycocerosate exporter MmpL7
up seq anno feature ids: PRO_0000103570

83332:Rv0153c
gene id: 83332:Rv0153c
uniprot id: I6WXK4
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Abolished binding to host ubiquitin.
up seq anno comments: Important for activity
up seq anno comments: Important for substrate specificity
up seq anno comments: Loss of activity.
up seq anno comments: No change in activity.
up seq anno comments: Phosphocysteine intermediate
up seq anno comments: Shows less than 0.1% of wild-type activity with peptides substrates.
up seq anno comments: Shows less than 1% of wild-type activity.
up seq anno comments: Shows less than 1% of wild-type activity. Does not affect macrophage apoptosis.
up seq anno comments: Shows less than 10% of the wild-type activity towards phosphotyrosine peptides, but remains unaltered towards pNPP and phosphoserine/threonine peptides.
up seq anno comments: Shows new activity for di-phosphorylated substrates PI(3,4)P2, PI(4,5)P2 and PI(3,4,5)P3.
up seq anno comments: Triple specificity protein phosphatase PtpB
up seq anno comments: UIM-like region
up seq anno feature ids: PRO_0000450734

83332:Rv3272
gene id: 83332:Rv3272
uniprot id: P96877
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Nucleophile
up seq anno comments: Probable fatty acyl-CoA transferase Rv3272
up seq anno feature ids: PRO_0000447345

83332:Rv2243
gene id: 83332:Rv2243
uniprot id: P9WNG5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Malonyl CoA-acyl carrier protein transacylase
up seq anno comments: Nearly abolishes pupylation and dramatically stabilizes this proteasome substrate in wild-type mycobacteria.
up seq anno feature ids: PRO_0000194218

83332:Rv3079c
gene id: 83332:Rv3079c
uniprot id: I6XG43
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv1175c
gene id: 83332:Rv1175c
uniprot id: O50431
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD/NAD(P)-binding
up seq anno comments: NADH:flavin oxidoreductase/NADH oxidase N-terminal

83332:Rv2914c
gene id: 83332:Rv2914c
uniprot id: P9WI69
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Favors the presence of monomers in solution.
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Results in a conformational transition from dimer to monomer.
up seq anno comments: Serine/threonine-protein kinase PknI
up seq anno feature ids: PRO_0000171220

83332:Rv3782
gene id: 83332:Rv3782
uniprot id: P9WMX3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Galactofuranosyltransferase GlfT1
up seq anno feature ids: PRO_0000395355

83332:Rv3763
gene id: 83332:Rv3763
uniprot id: P9WK61
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno comments: Decreased ConA binding; altered protein processing yields 21 and 16 kDa forms in M.smegmatis.
up seq anno comments: Decreased ConA binding; altered protein processing yields 21 and 17 kDa forms in M.smegmatis.
up seq anno comments: Disordered
up seq anno comments: Expressed in M.bovis, lipidated.
up seq anno comments: Lipoprotein LpqH
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: No ConA binding; altered protein processing yields 16 kDa soluble form starting on residue 40 in M.smegmatis. Protein poorly released into host cytoplasm (uses recombinant M.vaccae to infect mouse macrophages).
up seq anno comments: Polar residues
up seq anno comments: Prevents bacterial uptake by a human macrophage-like cell line
up seq anno comments: Protein not exported from cytoplasm, not released into host cytoplasm (uses recombinant M.vaccae to infect mouse macrophages).
up seq anno comments: Protein not released into host cytoplasm (uses recombinant M.vaccae to infect mouse macrophages).
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018128

83332:Rv0453
gene id: 83332:Rv0453
uniprot id: P9WI39
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PPE family protein PPE11
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000379585

83332:Rv1830
gene id: 83332:Rv1830
uniprot id: P9WME5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: HTH merR-type
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv1830
up seq anno feature ids: PRO_0000098170

83332:Rv2219A
gene id: 83332:Rv2219A
uniprot id: Q79FG7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: RDD

83332:Rv0099
gene id: 83332:Rv0099
uniprot id: P9WQ55
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase FadD10
up seq anno feature ids: PRO_0000420403

83332:Rv1790
gene id: 83332:Rv1790
uniprot id: Q79FK5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE
up seq anno comments: PPE family C-terminal

83332:Rv1287
gene id: 83332:Rv1287
uniprot id: P9WME3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: HTH rrf2-type
up seq anno comments: Putative HTH-type transcriptional regulator Rv1287
up seq anno feature ids: PRO_0000036205

83332:Rv1642
gene id: 83332:Rv1642
uniprot id: P9WH91
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL35
up seq anno feature ids: PRO_0000177387

83332:Rv3028c
gene id: 83332:Rv3028c
uniprot id: P9WNG9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Electron transfer flavoprotein subunit alpha
up seq anno feature ids: PRO_0000167853

83332:Rv2140c
gene id: 83332:Rv2140c
uniprot id: P9WFN1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: UPF0098 protein Rv2140c
up seq anno feature ids: PRO_0000137909

83332:Rv1945
gene id: 83332:Rv1945
uniprot id: P9WLQ5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HNH
up seq anno comments: Uncharacterized protein Rv1945
up seq anno feature ids: PRO_0000103914

83332:Rv3139
gene id: 83332:Rv3139
uniprot id: P95187
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle
up seq anno comments: Disordered

83332:Rv1761c
gene id: 83332:Rv1761c
uniprot id: O06796
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2611c
gene id: 83332:Rv2611c
uniprot id: P9WMB5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Phosphatidylinositol mannoside acyltransferase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000393105

83332:Rv2253
gene id: 83332:Rv2253
uniprot id: O53527
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Secreted protein
up seq anno feature ids: PRO_5039045319

83332:Rv3443c
gene id: 83332:Rv3443c
uniprot id: P9WHE1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein uL13
up seq anno feature ids: PRO_0000133744

83332:Rv0680c
gene id: 83332:Rv0680c
uniprot id: I6Y4F1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5038496935

83332:Rv3816c
gene id: 83332:Rv3816c
uniprot id: O07807
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv2441c
gene id: 83332:Rv2441c
uniprot id: P9WHB3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL27
up seq anno feature ids: PRO_0000181130

83332:Rv3260c
gene id: 83332:Rv3260c
uniprot id: O53353
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: Considerable loss of chaperone activity.
up seq anno comments: Disordered
up seq anno comments: Fully oxidized recombinant protein tagged at both termini.
up seq anno comments: Fully reduced recombinant protein tagged at both termini.
up seq anno comments: Phosphoserine
up seq anno comments: Retains chaperone activity; when associated with A-27, A-50 and A-53.
up seq anno comments: Retains chaperone activity; when associated with A-27, A-50 and A-59.
up seq anno comments: Retains chaperone activity; when associated with A-27, A-53 and A-59.
up seq anno comments: Retains chaperone activity; when associated with A-50, A-53 and A-59.
up seq anno comments: Transcriptional regulator WhiB2
up seq anno feature ids: PRO_0000420380

83332:Rv2126c
gene id: 83332:Rv2126c
uniprot id: L0TBL4
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1340
gene id: 83332:Rv1340
uniprot id: P9WGZ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Ribonuclease PH
up seq anno feature ids: PRO_0000139912

83332:Rv0989c
gene id: 83332:Rv0989c
uniprot id: O05572
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno comments: DDXXD motif
up seq anno comments: Dimethylallyltranstransferase
up seq anno comments: Important for determining product chain length
up seq anno comments: Leads to the production of longer chain product, specifically (E,E)-farnesyl diphosphate (FPP), in addition to GPP.
up seq anno feature ids: PRO_0000451294

83332:Rv2173
gene id: 83332:Rv2173
uniprot id: O53507
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: (2E,6E)-farnesyl diphosphate synthase
up seq anno comments: DDXXD motif
up seq anno feature ids: PRO_0000451295

83332:Rv0802c
gene id: 83332:Rv0802c
uniprot id: P9WQG7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acetyl- and succinyl-CoA transferase Rv0802c
up seq anno comments: N-acetyltransferase
up seq anno feature ids: PRO_0000414586

83332:Rv1143
gene id: 83332:Rv1143
uniprot id: O06543
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 10.1% of wild-type activity.
up seq anno comments: 12.5% of wild-type activity.
up seq anno comments: 15.7% of wild-type activity.
up seq anno comments: 17.6 of wild-type activity.
up seq anno comments: 19.9% of wild-type activity.
up seq anno comments: 2.1% of wild-type activity.
up seq anno comments: 28.8% of wild-type activity.
up seq anno comments: 3.3% of wild-type activity.
up seq anno comments: 4.5% of wild-type activity.
up seq anno comments: 5.2% of wild-type activity.
up seq anno comments: 6.2% of wild-type activity.
up seq anno comments: Alpha-methylacyl-CoA racemase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000449922

83332:Rv2836c
gene id: 83332:Rv2836c
uniprot id: P71616
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0629c
gene id: 83332:Rv0629c
uniprot id: P9WHJ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: RecBCD enzyme subunit RecD
up seq anno feature ids: PRO_0000390680

83332:Rv0948c
gene id: 83332:Rv0948c
uniprot id: P9WIC1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno comments: Chorismate mutase
up seq anno comments: Important for activation via AroG
up seq anno comments: Important for catalysis
up seq anno comments: Intracellular chorismate mutase
up seq anno comments: It is catalytically catastrophic, but strongly activated by AroG.
up seq anno comments: The catalytic efficiency and the affinity are 5 and 3-fold lower than the wild-type. The activation by AroG is 10-fold lower than the wild-type.
up seq anno comments: The catalytic efficiency and the affinity are higher than the wild-type. The activation by AroG is 20-fold lower than the wild-type.
up seq anno comments: The catalytic efficiency and the affinity are identical to the wild-type. The activation by AroG is 10-fold lower than the wild type.
up seq anno comments: The catalytic efficiency and the affinity are slightly modified. The activation by AroG is 2-fold lower than the wild-type.
up seq anno feature ids: PRO_0000119200

83332:Rv0593
gene id: 83332:Rv0593
uniprot id: I6Y461
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv3504
gene id: 83332:Rv3504
uniprot id: I6YCA3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-CoA dehydrogenase FadE26
up seq anno comments: Loss of dehydrogenase activity.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000438520

83332:Rv1604
gene id: 83332:Rv1604
uniprot id: O53907
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable inositol 1-monophosphatase ImpA
up seq anno feature ids: PRO_0000404321

83332:Rv0023
gene id: 83332:Rv0023
uniprot id: P9WMI3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0023
up seq anno feature ids: PRO_0000149772

83332:Rv1259
gene id: 83332:Rv1259
uniprot id: P9WM53
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Type-5 uracil-DNA glycosylase
up seq anno feature ids: PRO_0000103774

83332:Rv2952
gene id: 83332:Rv2952
uniprot id: P9WIN3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase
up seq anno feature ids: PRO_0000305165

83332:Rv2437
gene id: 83332:Rv2437
uniprot id: P71912
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1926c
gene id: 83332:Rv1926c
uniprot id: P9WIP1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Immunogenic protein MPT63
up seq anno feature ids: PRO_0000021736

83332:Rv2784c
gene id: 83332:Rv2784c
uniprot id: I6XFA6
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010168519

83332:Rv3089
gene id: 83332:Rv3089
uniprot id: P9WQ37
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alteration of the strength of the membrane binding; when associated with A-17; A-195; A-195 and A-197.
up seq anno comments: Alteration of the strength of the membrane binding; when associated with A-9; A-17; A-195 and A-244.
up seq anno comments: Alteration of the strength of the membrane binding; when associated with A-9; A-17; A-197 and A-244.
up seq anno comments: Alteration of the strength of the membrane binding; when associated with A-9; A-195; A-197 and A-244.
up seq anno comments: Does not show activity with small, medium or long acyl chains.
up seq anno comments: Important for substrate selectivity
up seq anno comments: Long-chain-fatty-acid--CoA ligase FadD13
up seq anno comments: Membrane interaction
up seq anno comments: No effect on the formation of acyl-adenylate intermediate. However, it shows very poor catalytic efficiency to form acyl-CoA.
up seq anno comments: Reduction of binding affinity for fatty acids.
up seq anno comments: Shows a marked decrease in the activity with lauric and palmitic acid (C12 and C16 fatty acid) with a simultaneous increase in the activity with caprylic acid (C8 fatty acid).
up seq anno comments: Slight increase of the fatty acyl-CoA ligase activity. Reduced rate of proteolytic degradation.
up seq anno comments: Slight reduction of the fatty acyl-CoA ligase activity. Enhanced affinity towards palmitic acid binding.
up seq anno comments: Slight reduction of the fatty acyl-CoA ligase activity. Slight increase of susceptibility to proteolysis.
up seq anno comments: Strong reduction of the fatty acyl-CoA ligase activity. Enhanced affinity towards palmitic acid binding. No significant change in the total expression level, however the cytoplasmic expression is low. Slight increase of susceptibility to proteolysis.
up seq anno comments: Strong reduction of the fatty acyl-CoA ligase activity. No significant change in the total expression level, however the cytoplasmic expression is reduced.
up seq anno comments: Strong reduction of the fatty acyl-CoA ligase activity. No significant change in the total expression level, however the cytoplasmic expression is reduced. Slight increase of susceptibility to proteolysis.
up seq anno comments: Strong reduction of the fatty acyl-CoA ligase activity. Reduction of binding affinity for ATP.
up seq anno feature ids: PRO_0000420960

83332:Rv0892
gene id: 83332:Rv0892
uniprot id: P9WNG1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Transition state stabilizer
up seq anno comments: Uncharacterized monooxygenase Rv0892
up seq anno feature ids: PRO_0000186458

83332:Rv3634c
gene id: 83332:Rv3634c
uniprot id: P9WN67
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Proton acceptor
up seq anno comments: UDP-glucose 4-epimerase
up seq anno feature ids: PRO_0000420762

83332:Rv2924c
gene id: 83332:Rv2924c
uniprot id: P9WNC3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Zinc Finger
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Zinc Finger
up seq anno comments: FPG-type
up seq anno comments: Formamidopyrimidine-DNA glycosylase 1
up seq anno comments: Proton donor
up seq anno comments: Proton donor; for beta-elimination activity
up seq anno comments: Proton donor; for delta-elimination activity
up seq anno comments: Removed
up seq anno comments: Schiff-base intermediate with DNA
up seq anno feature ids: PRO_0000170840

83332:Rv2328
gene id: 83332:Rv2328
uniprot id: P9WIG9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: PE
up seq anno comments: Uncharacterized PE family protein PE23
up seq anno feature ids: PRO_0000216162

83332:Rv0823c
gene id: 83332:Rv0823c
uniprot id: P9WNS7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable tRNA-dihydrouridine synthase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000162137

83332:Rv3447c
gene id: 83332:Rv3447c
uniprot id: P9WNA7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ESX-4 secretion system protein EccC4
up seq anno comments: FtsK 1
up seq anno comments: FtsK 2
up seq anno comments: FtsK 3
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393431

83332:Rv3892c
gene id: 83332:Rv3892c
uniprot id: P9WHW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE69
up seq anno feature ids: PRO_0000379594

83332:Rv0511
gene id: 83332:Rv0511
uniprot id: Q6MX34
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Tetrapyrrole biosynthesis uroporphyrinogen III synthase
up seq anno comments: Tetrapyrrole methylase

83332:Rv0288
gene id: 83332:Rv0288
uniprot id: P9WNK3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ESAT-6-like protein EsxH
up seq anno comments: No change in activity.
up seq anno comments: Still interacts with EsxG, but impairs interaction with host HGS/HRS; when associated with A-76.
up seq anno comments: Still interacts with EsxG, but impairs interaction with host HGS/HRS; when associated with A-77.
up seq anno feature ids: PRO_0000167798

83332:Rv3411c
gene id: 83332:Rv3411c
uniprot id: P9WKI7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: Inosine-5'-monophosphate dehydrogenase
up seq anno comments: Proton acceptor
up seq anno comments: Thioimidate intermediate
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000093702

83332:Rv0651
gene id: 83332:Rv0651
uniprot id: P9WHE7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL10
up seq anno feature ids: PRO_0000154674

83332:Rv1841c
gene id: 83332:Rv1841c
uniprot id: P9WLQ7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: CNNM transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1841c
up seq anno feature ids: PRO_0000103913

83332:Rv2352c
gene id: 83332:Rv2352c
uniprot id: P9WHZ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE38
up seq anno feature ids: PRO_0000378482

83332:Rv0465c
gene id: 83332:Rv0465c
uniprot id: P9WMI1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: HTH-type transcriptional regulator RamB
up seq anno feature ids: PRO_0000382634

83332:Rv3601c
gene id: 83332:Rv3601c
uniprot id: P9WIL3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Aspartate 1-decarboxylase alpha chain
up seq anno comments: Aspartate 1-decarboxylase beta chain
up seq anno comments: In S11; may confer PZA resistance; when associated with R-21.
up seq anno comments: In S11; may confer PZA resistance; when associated with V-49.
up seq anno comments: In S13; may confer PZA resistance.
up seq anno comments: In S6; may confer PZA resistance.
up seq anno comments: In S9, S10; may confer PZA resistance.
up seq anno comments: Proton donor
up seq anno comments: Pyruvic acid (Ser)
up seq anno comments: Schiff-base intermediate with substrate; via pyruvic acid
up seq anno feature ids: PRO_0000023121
up seq anno feature ids: PRO_0000023122

83332:Rv0111
gene id: 83332:Rv0111
uniprot id: O53633
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Acyltransferase 3
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: SGNH

83332:Rv1654
gene id: 83332:Rv1654
uniprot id: P9WQ01
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acetylglutamate kinase
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000112637

83332:Rv3038c
gene id: 83332:Rv3038c
uniprot id: I6YAZ1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase type 11

83332:Rv0292
gene id: 83332:Rv0292
uniprot id: P9WJE5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-3 secretion system protein EccE3
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393871

83332:Rv0769
gene id: 83332:Rv0769
uniprot id: P9WGQ9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv0769
up seq anno feature ids: PRO_0000415505

83332:Rv2484c
gene id: 83332:Rv2484c
uniprot id: P9WKB3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv2484c
up seq anno feature ids: PRO_0000222912

83332:Rv3426
gene id: 83332:Rv3426
uniprot id: Q50702
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE58
up seq anno feature ids: PRO_0000217854

83332:Rv1956
gene id: 83332:Rv1956
uniprot id: P9WJA7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Strand
up seq anno comments: Antitoxin HigA1
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno feature ids: PRO_0000407371

83332:Rv2447c
gene id: 83332:Rv2447c
uniprot id: I6Y0R5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Sequence Variant
up seq anno comments: Dihydrofolate synthase/folylpolyglutamate synthase
up seq anno comments: In a spontaneous PAS-resistant mutant strain.
up seq anno comments: In a spontaneous PAS-resistant mutant strain; complementation with wild-type folC restores PAS susceptibility, confirmimg that this mutation confers high level resistance to PAS.
up seq anno comments: In a spontaneous PAS-resistant mutant strain; complementation with wild-type folC restores PAS susceptibility.
up seq anno comments: In a spontaneous PAS-resistant mutant strain; complementation with wild-type folC restores PAS susceptibility; 5-fold reduction in DHFS activity relative to wild-type; loss of the ability to glutaminate H2PtePAS.
up seq anno comments: In clinical isolate: Q36; PAS-resistant; complementation with wild-type folC restores PAS susceptibility.
up seq anno comments: In clinical isolates: Q274 and 501063; PAS-resistant; complementation with wild-type folC restores PAS susceptibility.
up seq anno comments: In clinical isolates: Q449 and 1314; PAS-resistant; complementation with wild-type folC restores PAS susceptibility; 7-fold reduction in DHFS activity relative to wild-type; loss of the ability to glutaminate H2PtePAS.
up seq anno feature ids: PRO_0000439040

83332:Rv2805
gene id: 83332:Rv2805
uniprot id: P71646
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1774
gene id: 83332:Rv1774
uniprot id: O33177
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv2623
gene id: 83332:Rv2623
uniprot id: P9WFD7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: Reduces ATP-binding; M.tuberculosis overexpressing this protein grows normally.
up seq anno comments: Universal stress protein Rv2623
up seq anno feature ids: PRO_0000392628

83332:Rv2266
gene id: 83332:Rv2266
uniprot id: P9WPP3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Methyl-branched lipid omega-hydroxylase
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052278

83332:Rv3455c
gene id: 83332:Rv3455c
uniprot id: P9WHP9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: tRNA pseudouridine synthase A
up seq anno feature ids: PRO_0000057415

83332:Rv0691c
gene id: 83332:Rv0691c
uniprot id: P9WMB7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Putative mycofactocin biosynthesis transcriptional regulator MftR
up seq anno feature ids: PRO_0000415280

83332:Rv3827c
gene id: 83332:Rv3827c
uniprot id: O07796
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Probable transposase IS891/IS1136/IS1341
up seq anno comments: Transposase putative helix-turn-helix

83332:Rv2451
gene id: 83332:Rv2451
uniprot id: O53178
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1351
gene id: 83332:Rv1351
uniprot id: P9WM17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1351
up seq anno feature ids: PRO_0000103821

83332:Rv2740
gene id: 83332:Rv2740
uniprot id: O33283
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Epoxide hydrolase EphG
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000420415

83332:Rv1001
gene id: 83332:Rv1001
uniprot id: P9WQ05
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Amidino-cysteine intermediate
up seq anno comments: Arginine deiminase
up seq anno feature ids: PRO_0000182223

83332:Rv1852
gene id: 83332:Rv1852
uniprot id: P9WFE3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Interchain
up seq anno comments: Urease accessory protein UreG
up seq anno feature ids: PRO_0000067669

83332:Rv0813c
gene id: 83332:Rv0813c
uniprot id: P9WFG9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: GXWXGXG
up seq anno comments: N-acetylserine
up seq anno comments: Peroxynitrite isomerase 2
up seq anno comments: Removed
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000356933

83332:Rv1664
gene id: 83332:Rv1664
uniprot id: O06586
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv0640
gene id: 83332:Rv0640
uniprot id: P9WHE5
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Large ribosomal subunit protein uL11
up seq anno feature ids: PRO_0000104325

83332:Rv2846c
gene id: 83332:Rv2846c
uniprot id: P9WJY5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter EfpA
up seq anno feature ids: PRO_0000390888

83332:Rv1991A
gene id: 83332:Rv1991A
uniprot id: P9WJ87
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Antitoxin MazE6
up seq anno comments: No DNA-binding.
up seq anno feature ids: PRO_0000406300

83332:Rv3580c
gene id: 83332:Rv3580c
uniprot id: P9WFW1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Cysteine--tRNA ligase
up seq anno feature ids: PRO_0000159441

83332:Rv1475c
gene id: 83332:Rv1475c
uniprot id: O53166
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Aconitate hydratase A
up seq anno feature ids: PRO_0000432979

83332:Rv1301
gene id: 83332:Rv1301
uniprot id: P9WGC9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Putative threonylcarbamoyl-AMP synthase
up seq anno comments: YrdC-like
up seq anno feature ids: PRO_0000202025

83332:Rv3520c
gene id: 83332:Rv3520c
uniprot id: O53565
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative coenzyme F420-dependent oxidoreductase Rv3520c
up seq anno feature ids: PRO_0000415512

83332:Rv0433
gene id: 83332:Rv0433
uniprot id: P9WPK9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative glutamate--cysteine ligase 2
up seq anno feature ids: PRO_0000218208

83332:Rv1614
gene id: 83332:Rv1614
uniprot id: P9WK93
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
up seq anno feature ids: PRO_0000172639

83332:Rv2146c
gene id: 83332:Rv2146c
uniprot id: O06230
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1786
gene id: 83332:Rv1786
uniprot id: O53937
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ferredoxin FdxE
up seq anno feature ids: PRO_0000458138

83332:Rv1269c
gene id: 83332:Rv1269c
uniprot id: P9WM45
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Protein Rv1269c
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000014089

83332:Rv2962c
gene id: 83332:Rv2962c
uniprot id: P9WN09
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: PGL/p-HBAD biosynthesis rhamnosyltransferase
up seq anno feature ids: PRO_0000313792

83332:Rv1936
gene id: 83332:Rv1936
uniprot id: P95278
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv2794c
gene id: 83332:Rv2794c
uniprot id: O33336
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 100-fold decrease in phosphopantetheinylation activity.
up seq anno comments: 20-fold decrease in phosphopantetheinylation activity.
up seq anno comments: 4'-phosphopantetheinyl transferase PptT
up seq anno comments: 500-fold decrease in phosphopantetheinylation activity.
up seq anno comments: Abolishes phosphopantetheinylation activity.
up seq anno comments: Confers high-level resistance to compound 8918.
up seq anno feature ids: PRO_0000451441

83332:Rv3646c
gene id: 83332:Rv3646c
uniprot id: P9WG49
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Basic residues
up seq anno comments: DNA topoisomerase 1
up seq anno comments: Disordered
up seq anno comments: Interaction with DNA
up seq anno comments: O-(5'-phospho-DNA)-tyrosine intermediate
up seq anno comments: Toprim
up seq anno feature ids: PRO_0000145159

83332:Rv0838
gene id: 83332:Rv0838
uniprot id: O53850
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: D-alanyl-D-alanine dipeptidase
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_5030174835

83332:Rv2590
gene id: 83332:Rv2590
uniprot id: Q50631
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: Carboxylic acid reductase
up seq anno comments: Carrier
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno feature ids: PRO_0000451306

83332:Rv3459c
gene id: 83332:Rv3459c
uniprot id: P9WH65
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Small ribosomal subunit protein uS11
up seq anno feature ids: PRO_0000123185

83332:Rv0336
gene id: 83332:Rv0336
uniprot id: O33266
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HNH nuclease
up seq anno comments: Polar residues

83332:Rv3785
gene id: 83332:Rv3785
uniprot id: P9WKX1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3785
up seq anno feature ids: PRO_0000104148

83332:Rv0300
gene id: 83332:Rv0300
uniprot id: O07227
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: Antitoxin VapB2
up seq anno feature ids: PRO_0000408052

83332:Rv3421c
gene id: 83332:Rv3421c
uniprot id: P9WKY7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv3421c
up seq anno feature ids: PRO_0000014153

83332:Rv0661c
gene id: 83332:Rv0661c
uniprot id: P9WFB3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC7
up seq anno feature ids: PRO_0000407870

83332:Rv0478
gene id: 83332:Rv0478
uniprot id: P9WP03
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Deoxyribose-phosphate aldolase
up seq anno comments: Proton donor/acceptor
up seq anno comments: Schiff-base intermediate with acetaldehyde
up seq anno feature ids: PRO_0000057248

83332:Rv3614c
gene id: 83332:Rv3614c
uniprot id: P9WJD5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Absence of EspD secretion.
up seq anno comments: Absence of EspD secretion. Decreases EspA levels.
up seq anno comments: Absence of EsxA secretion. Decreases EspD stability.
up seq anno comments: Decreased EspD secretion and small reduction in cellular EspA levels.
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion-associated protein EspD
up seq anno feature ids: PRO_0000393904

83332:Rv0121c
gene id: 83332:Rv0121c
uniprot id: O07171
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Pyridoxamine 5'-phosphate oxidase putative

83332:Rv0959
gene id: 83332:Rv0959
uniprot id: P9WKN1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0959
up seq anno feature ids: PRO_0000103753

83332:Rv1148c
gene id: 83332:Rv1148c
uniprot id: P9WM55
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: HNH
up seq anno comments: Uncharacterized protein Rv1148c
up seq anno feature ids: PRO_0000103770

83332:Rv0779c
gene id: 83332:Rv0779c
uniprot id: P71833
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2496c
gene id: 83332:Rv2496c
uniprot id: P9WIS1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 3-methyl-2-oxobutanoate dehydrogenase subunit beta
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000420519

83332:Rv3514
gene id: 83332:Rv3514
uniprot id: Q6MWW6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv2468A
gene id: 83332:Rv2468A
uniprot id: I6YDH3
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1625c
gene id: 83332:Rv1625c
uniprot id: P9WQ35
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Abolishes homodimerization and strongly decreases enzyme activitywhen associated with E-296 and R-363.
up seq anno comments: Adenylate cyclase
up seq anno comments: Almost complete loss of enzyme activity.
up seq anno comments: Almost no loss of activity.
up seq anno comments: Cytoplasmic
up seq anno comments: Decreased enzyme activity.
up seq anno comments: Guanylate cyclase
up seq anno comments: Helical
up seq anno comments: Loss of activity.
up seq anno comments: Promotes formation of a domain-swapped dimer. Abolishes homodimerization and strongly decreases enzyme activity; when associated with E-296 and C-365.
up seq anno comments: Strongly decreased enzyme activity. Abolishes homodimerization and strongly decreases enzyme activity; when associated with R-363 and C-365.
up seq anno feature ids: PRO_0000195727

83332:Rv1967
gene id: 83332:Rv1967
uniprot id: O53968
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv0598c
gene id: 83332:Rv0598c
uniprot id: P9WF83
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC27
up seq anno feature ids: PRO_0000407886

83332:Rv3731
gene id: 83332:Rv3731
uniprot id: L0TDE1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: DNA ligase C
up seq anno comments: N6-AMP-lysine intermediate
up seq anno feature ids: PRO_0000425953

83332:Rv2818c
gene id: 83332:Rv2818c
uniprot id: P71635
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: CARF domain
up seq anno comments: CRISPR system endoribonuclease Csm6
up seq anno comments: HEPN domain
up seq anno feature ids: PRO_0000418229

83332:Rv2633c
gene id: 83332:Rv2633c
uniprot id: P9WL59
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2633c
up seq anno feature ids: PRO_0000104074

83332:Rv0423c
gene id: 83332:Rv0423c
uniprot id: P9WG79
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Phosphomethylpyrimidine synthase
up seq anno feature ids: PRO_0000152815

83332:Rv3145
gene id: 83332:Rv3145
uniprot id: P9WIW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NADH-quinone oxidoreductase subunit A
up seq anno feature ids: PRO_0000117870

83332:Rv2462c
gene id: 83332:Rv2462c
uniprot id: P9WG55
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: PPIase FKBP-type
up seq anno comments: Trigger factor
up seq anno feature ids: PRO_0000179391

83332:Rv3100c
gene id: 83332:Rv3100c
uniprot id: P9WGD3
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: SsrA-binding protein
up seq anno feature ids: PRO_0000102991

83332:Rv3287c
gene id: 83332:Rv3287c
uniprot id: P9WGX7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Anti-sigma-F factor RsbW
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000422955

83332:Rv2934
gene id: 83332:Rv2934
uniprot id: P9WQE3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acyltransferase
up seq anno comments: Beta-ketoacyl reductase
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase
up seq anno comments: Disordered
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: For malonyltransferase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Phenolphthiocerol/phthiocerol polyketide synthase subunit D
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno feature ids: PRO_0000406950

83332:Rv0183
gene id: 83332:Rv0183
uniprot id: O07427
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Charge relay system
up seq anno comments: Loss of lipase activity.
up seq anno comments: Monoacylglycerol lipase
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000438237

83332:Rv1575
gene id: 83332:Rv1575
uniprot id: L0T9U5
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1362c
gene id: 83332:Rv1362c
uniprot id: P9WM01
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1362c
up seq anno feature ids: PRO_0000103831

83332:Rv2752c
gene id: 83332:Rv2752c
uniprot id: P9WGZ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Not absolutely required for RNase activity
up seq anno comments: Required for beta-lactamase activity
up seq anno comments: Ribonuclease J
up seq anno comments: Significantly decreased beta-lactamase and RNase activity.
up seq anno feature ids: PRO_0000395887

83332:Rv3104c
gene id: 83332:Rv3104c
uniprot id: O05781
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2580c
gene id: 83332:Rv2580c
uniprot id: P9WFV5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Histidine--tRNA ligase
up seq anno feature ids: PRO_0000136196

83332:Rv0558
gene id: 83332:Rv0558
uniprot id: P9WFR3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Demethylmenaquinone methyltransferase
up seq anno feature ids: PRO_0000193297

83332:Rv0306
gene id: 83332:Rv0306
uniprot id: O07233
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nitroreductase

83332:Rv3653
gene id: 83332:Rv3653
uniprot id: Q6MWV0
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Decreases Ca(2+) binding affinity.
up seq anno comments: PE-PGRS family protein PE_PGRS61
up seq anno feature ids: PRO_0000438250

83332:Rv1486c
gene id: 83332:Rv1486c
uniprot id: P9WLX3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1486c
up seq anno feature ids: PRO_0000103853

83332:Rv1918c
gene id: 83332:Rv1918c
uniprot id: Q79FI8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE

83332:Rv1977
gene id: 83332:Rv1977
uniprot id: O53978
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Peptidase M48

83332:Rv2338c
gene id: 83332:Rv2338c
uniprot id: P95234
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: THIF-type NAD/FAD binding fold

83332:Rv0445c
gene id: 83332:Rv0445c
uniprot id: P9WGH7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Turn
up seq anno comments: ECF RNA polymerase sigma factor SigK
up seq anno comments: H-T-H motif
up seq anno comments: Interaction with polymerase core subunit RpoC
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000313845

83332:Rv1311
gene id: 83332:Rv1311
uniprot id: P9WPV1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP synthase epsilon chain
up seq anno comments: Removed
up seq anno feature ids: PRO_0000188166

83332:Rv2156c
gene id: 83332:Rv2156c
uniprot id: P9WMW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Phospho-N-acetylmuramoyl-pentapeptide-transferase
up seq anno feature ids: PRO_0000108856

83332:Rv0297
gene id: 83332:Rv0297
uniprot id: Q6MX50
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS5
up seq anno comments: PGRS
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000445087

83332:Rv1811
gene id: 83332:Rv1811
uniprot id: I6YBN6
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2972c
gene id: 83332:Rv2972c
uniprot id: I6X5W6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF1524

83332:Rv1982c
gene id: 83332:Rv1982c
uniprot id: P9WF65
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC36
up seq anno feature ids: PRO_0000221201

83332:Rv0701
gene id: 83332:Rv0701
uniprot id: P9WH87
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL3
up seq anno feature ids: PRO_0000077125

83332:Rv3660c
gene id: 83332:Rv3660c
uniprot id: P9WKX7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3660c
up seq anno feature ids: PRO_0000390676

83332:Rv1376
gene id: 83332:Rv1376
uniprot id: P71804
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: TfuA-like core

83332:Rv2602
gene id: 83332:Rv2602
uniprot id: P9WF59
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC41
up seq anno feature ids: PRO_0000407895

83332:Rv3470c
gene id: 83332:Rv3470c
uniprot id: O06335
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Putative acetolactate synthase large subunit IlvB2
up seq anno comments: Thiamine pyrophosphate binding
up seq anno feature ids: PRO_0000396952

83332:Rv0347
gene id: 83332:Rv0347
uniprot id: O06298
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3795
gene id: 83332:Rv3795
uniprot id: P9WNL7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Helical
up seq anno comments: Probable arabinosyltransferase B
up seq anno comments: Resistance to EMB.
up seq anno feature ids: PRO_0000220569

83332:Rv0138
gene id: 83332:Rv0138
uniprot id: P96815
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv0969
gene id: 83332:Rv0969
uniprot id: P9WPS3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Disordered
up seq anno comments: HMA
up seq anno comments: Helical
up seq anno comments: Probable copper-exporting P-type ATPase V
up seq anno feature ids: PRO_0000046348

83332:Rv1159
gene id: 83332:Rv1159
uniprot id: P9WN01
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol pentamannoside mannosyltransferase
up seq anno feature ids: PRO_0000393738

83332:Rv1321
gene id: 83332:Rv1321
uniprot id: P9WIY5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Endonuclease NucS
up seq anno feature ids: PRO_0000155685

83332:Rv0791c
gene id: 83332:Rv0791c
uniprot id: I6X9T8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv1635c
gene id: 83332:Rv1635c
uniprot id: O06152
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Glycosyltransferase RgtA/B/C/D-like
up seq anno comments: Helical

83332:Rv3136A
gene id: 83332:Rv3136A
uniprot id: I6Y2Q7
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2506
gene id: 83332:Rv2506
uniprot id: O06169
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3743c
gene id: 83332:Rv3743c
uniprot id: P9WPT7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Helical
up seq anno comments: Probable cation-transporting P-type ATPase J
up seq anno feature ids: PRO_0000419203

83332:Rv0973c
gene id: 83332:Rv0973c
uniprot id: P71538
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ATP-grasp
up seq anno comments: Biotin carboxylation
up seq anno comments: Lipoyl-binding

83332:Rv1465
gene id: 83332:Rv1465
uniprot id: O53156
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NIF system FeS cluster assembly NifU N-terminal

83332:Rv3155
gene id: 83332:Rv3155
uniprot id: P9WIX3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NADH-quinone oxidoreductase subunit K
up seq anno feature ids: PRO_0000118532

83332:Rv3114
gene id: 83332:Rv3114
uniprot id: O05791
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CMP/dCMP-type deaminase

83332:Rv0370c
gene id: 83332:Rv0370c
uniprot id: O53705
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA+ ATPase

83332:Rv3299c
gene id: 83332:Rv3299c
uniprot id: O65931
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Sulfatase N-terminal

83332:Rv3842c
gene id: 83332:Rv3842c
uniprot id: P9WMU3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: GP-PDE
up seq anno comments: Probable glycerophosphodiester phosphodiesterase 1
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000392941

83332:Rv2944
gene id: 83332:Rv2944
uniprot id: P96287
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: AAA+ ATPase
up seq anno comments: Disordered

83332:Rv0193c
gene id: 83332:Rv0193c
uniprot id: O07437
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3807c
gene id: 83332:Rv3807c
uniprot id: P9WI53
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative decaprenylphosphoryl-5-phosphoribose phosphatase Rv3807c
up seq anno feature ids: PRO_0000420590

83332:Rv2763c
gene id: 83332:Rv2763c
uniprot id: P9WNX1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: DHFR
up seq anno comments: Dihydrofolate reductase
up seq anno feature ids: PRO_0000186400

83332:Rv3121
gene id: 83332:Rv3121
uniprot id: P9WPL7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative cytochrome P450 141
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052303

83332:Rv0009
gene id: 83332:Rv0009
uniprot id: P9WHW3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: PPIase cyclophilin-type
up seq anno comments: Peptidyl-prolyl cis-trans isomerase A
up seq anno feature ids: PRO_0000064209

83332:Rv3638
gene id: 83332:Rv3638
uniprot id: I6XHU7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: IstB-like ATP-binding

83332:Rv2530A
gene id: 83332:Rv2530A
uniprot id: P9WJ23
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB39
up seq anno feature ids: PRO_0000408081

83332:Rv0488
gene id: 83332:Rv0488
uniprot id: P9WK33
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative amino-acid transporter Rv0488
up seq anno feature ids: PRO_0000103692

83332:Rv0717
gene id: 83332:Rv0717
uniprot id: P9WH57
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein uS14B
up seq anno feature ids: PRO_0000130910

83332:Rv3428c
gene id: 83332:Rv3428c
uniprot id: Q50700
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Integrase catalytic
up seq anno comments: Putative transposase Rv3428c
up seq anno feature ids: PRO_0000075471

83332:Rv2527
gene id: 83332:Rv2527
uniprot id: P9WF95
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC17
up seq anno feature ids: PRO_0000407876

83332:Rv3796
gene id: 83332:Rv3796
uniprot id: P72062
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv0316
gene id: 83332:Rv0316
uniprot id: O07243
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Muconolactone isomerase

83332:Rv1171
gene id: 83332:Rv1171
uniprot id: O50427
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1497
gene id: 83332:Rv1497
uniprot id: P71778
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 60% loss of esterase activity.
up seq anno comments: 70% loss of esterase activity.
up seq anno comments: 80% loss of esterase and beta-lactamase activities.
up seq anno comments: 90% loss of esterase activity.
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Almost no change in esterase and beta-lactamase activities.
up seq anno comments: Esterase/beta-lactamase LipL
up seq anno comments: Loss of esterase and beta-lactamase activities.
up seq anno feature ids: PRO_0000448854

83332:Rv0127
gene id: 83332:Rv0127
uniprot id: O07177
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Maltokinase
up seq anno feature ids: PRO_0000412894

83332:Rv3247c
gene id: 83332:Rv3247c
uniprot id: P9WKE1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: LID
up seq anno comments: Thymidylate kinase
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000155309

83332:Rv2349c
gene id: 83332:Rv2349c
uniprot id: P9WIB1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Phospholipase C C
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000023944

83332:Rv0986
gene id: 83332:Rv0986
uniprot id: P9WQK1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Uncharacterized ABC transporter ATP-binding protein Rv0986
up seq anno feature ids: PRO_0000093254

83332:Rv3544c
gene id: 83332:Rv3544c
uniprot id: P71857
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Acyl-CoA dehydrogenase FadE28
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000438517

83332:Rv0457c
gene id: 83332:Rv0457c
uniprot id: O07178
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Peptidase S9 prolyl oligopeptidase catalytic
up seq anno comments: Peptidase S9A N-terminal

83332:Rv2170
gene id: 83332:Rv2170
uniprot id: O53504
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase

83332:Rv1822
gene id: 83332:Rv1822
uniprot id: P9WPG5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative cardiolipin synthase
up seq anno feature ids: PRO_0000056779

83332:Rv1993c
gene id: 83332:Rv1993c
uniprot id: P9WLP5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1993c
up seq anno feature ids: PRO_0000103920

83332:Rv2644c
gene id: 83332:Rv2644c
uniprot id: P9WL53
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2644c
up seq anno feature ids: PRO_0000104078

83332:Rv2823c
gene id: 83332:Rv2823c
uniprot id: P71629
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A)
up seq anno comments: GGDEF
up seq anno comments: HD
up seq anno feature ids: PRO_0000418224

83332:Rv1116
gene id: 83332:Rv1116
uniprot id: O06568
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv3670
gene id: 83332:Rv3670
uniprot id: I6YCQ4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv2284
gene id: 83332:Rv2284
uniprot id: Q50681
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable carboxylic ester hydrolase LipM
up seq anno feature ids: PRO_0000448852

83332:Rv3134c
gene id: 83332:Rv3134c
uniprot id: P9WFD3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Universal stress protein Rv3134c
up seq anno feature ids: PRO_0000392630

83332:Rv2614c
gene id: 83332:Rv2614c
uniprot id: P9WFT5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Catalytic
up seq anno comments: Disordered
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: TGS
up seq anno comments: Threonine--tRNA ligase
up seq anno feature ids: PRO_0000101012

83332:Rv2113
gene id: 83332:Rv2113
uniprot id: O33248
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0915c
gene id: 83332:Rv0915c
uniprot id: P9WI33
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE14
up seq anno feature ids: PRO_0000379586

83332:Rv1016c
gene id: 83332:Rv1016c
uniprot id: P9WK59
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LpqT
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018131

83332:Rv0148
gene id: 83332:Rv0148
uniprot id: P96825
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Proton acceptor
up seq anno comments: Putative short-chain type dehydrogenase/reductase Rv0148
up seq anno feature ids: PRO_0000395884

83332:Rv1509
gene id: 83332:Rv1509
uniprot id: P9WLW3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1509
up seq anno feature ids: PRO_0000103863

83332:Rv1681
gene id: 83332:Rv1681
uniprot id: O33183
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Radical SAM core

83332:Rv1332
gene id: 83332:Rv1332
uniprot id: P9WM25
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno comments: CXXXC
up seq anno comments: Forms dimers independent of the oxidizing nature of the environment, but cannot interact with SigH and cannot rescue the growth defects of the deletion mutant; when associated with A-5.
up seq anno comments: Forms dimers independent of the oxidizing nature of the environment, but cannot interact with SigH and cannot rescue the growth defects of the deletion mutant; when associated with A-9.
up seq anno comments: Oxidative stress regulator AosR
up seq anno comments: Redox-active
up seq anno feature ids: PRO_0000103805

83332:Rv2108
gene id: 83332:Rv2108
uniprot id: P9WI01
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE36
up seq anno feature ids: PRO_0000379113

83332:Rv1645c
gene id: 83332:Rv1645c
uniprot id: P94979
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic

83332:Rv0382c
gene id: 83332:Rv0382c
uniprot id: P9WHK9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Orotate phosphoribosyltransferase
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000110712

83332:Rv1477
gene id: 83332:Rv1477
uniprot id: O53168
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes host cell invasion and survival in host macrophages.
up seq anno comments: Abolishes host cell invasion.
up seq anno comments: Loss of enzyme activity.
up seq anno comments: NlpC/P60
up seq anno comments: Nucleophile
up seq anno comments: Peptidoglycan endopeptidase RipA
up seq anno comments: Proton acceptor
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000413762

83332:Rv2304c
gene id: 83332:Rv2304c
uniprot id: P9WLD3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2304c
up seq anno feature ids: PRO_0000104013

83332:Rv3166c
gene id: 83332:Rv3166c
uniprot id: O53316
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: DUF4129
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv0095c
gene id: 83332:Rv0095c
uniprot id: Q10891
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative uncharacterized protein Rv0095c
up seq anno feature ids: PRO_0000103667

83332:Rv1284
gene id: 83332:Rv1284
uniprot id: P9WPJ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Beta-carbonic anhydrase 1
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000103784

83332:Rv3680
gene id: 83332:Rv3680
uniprot id: I6Y498
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Anion-transporting ATPase-like

83332:Rv3311
gene id: 83332:Rv3311
uniprot id: O53362
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Acidic residues
up seq anno comments: Disordered

83332:Rv3852
gene id: 83332:Rv3852
uniprot id: I6YHB0
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3495c
gene id: 83332:Rv3495c
uniprot id: I6Y3P1
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: Lipoprotein LprN
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000438419

83332:Rv0203
gene id: 83332:Rv0203
uniprot id: I6X8R5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno comments: Decrease in heme binding.
up seq anno comments: Decrease in heme binding. Strong decrease in heme binding; when associated with A-64.
up seq anno comments: Decrease in heme binding. Strong decrease in heme binding; when associated with A-90.
up seq anno comments: Does not bind heme.
up seq anno comments: Heme-binding protein Rv0203
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000432886

83332:Rv1595
gene id: 83332:Rv1595
uniprot id: P9WJJ9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Important in orienting the L-aspartate substrate
up seq anno comments: L-aspartate oxidase
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000184389

83332:Rv3648c
gene id: 83332:Rv3648c
uniprot id: P9WP75
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CSD
up seq anno comments: Probable cold shock protein A
up seq anno feature ids: PRO_0000100312

83332:Rv2634c
gene id: 83332:Rv2634c
uniprot id: P9WIE7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS46
up seq anno feature ids: PRO_0000216171

83332:Rv0499
gene id: 83332:Rv0499
uniprot id: P9WKT9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: DAGKc
up seq anno comments: Uncharacterized protein Rv0499
up seq anno feature ids: PRO_0000103703

83332:Rv2250c
gene id: 83332:Rv2250c
uniprot id: P9WMC5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv2250c
up seq anno feature ids: PRO_0000070670

83332:Rv0794c
gene id: 83332:Rv0794c
uniprot id: I6Y4U4
up seq anno parent labels: Binding Site
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno comments: FAD/NAD(P)-binding
up seq anno comments: Pyridine nucleotide-disulphide oxidoreductase dimerisation
up seq anno comments: Redox-active

83332:Rv0677c
gene id: 83332:Rv0677c
uniprot id: P9WJS7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Siderophore export accessory protein MmpS5
up seq anno feature ids: PRO_0000216160

83332:Rv0327c
gene id: 83332:Rv0327c
uniprot id: P9WPN1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 135A1
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052292

83332:Rv1182
gene id: 83332:Rv1182
uniprot id: P9WIK5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Mass
up seq anno comments: Acyltransferase PapA3
up seq anno feature ids: PRO_0000420764

83332:Rv3257c
gene id: 83332:Rv3257c
uniprot id: O86374
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alpha-D-phosphohexomutase C-terminal
up seq anno comments: Alpha-D-phosphohexomutase alpha/beta/alpha

83332:Rv2921c
gene id: 83332:Rv2921c
uniprot id: P9WGD9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Severely affects the affinity toward GTP and causes a significant decrease in enzyme activity.
up seq anno comments: Signal recognition particle receptor FtsY
up seq anno feature ids: PRO_0000101139

83332:Rv0503c
gene id: 83332:Rv0503c
uniprot id: P9WPB5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno comments: Cyclopropane mycolic acid synthase 2
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000089569

83332:Rv3765c
gene id: 83332:Rv3765c
uniprot id: O69730
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Sequence Conflict
up seq anno comments: 4-aspartylphosphate
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Probable transcriptional regulatory protein TcrX
up seq anno comments: Response regulatory
up seq anno feature ids: PRO_0000412201

83332:Rv0997
gene id: 83332:Rv0997
uniprot id: O05580
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0468
gene id: 83332:Rv0468
uniprot id: P9WNP7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-hydroxybutyryl-CoA dehydrogenase
up seq anno comments: Important for catalytic activity
up seq anno comments: Loss of fatty acyl dehydrogenase activity.
up seq anno feature ids: PRO_0000403378

83332:Rv2656c
gene id: 83332:Rv2656c
uniprot id: P9WL49
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2656c
up seq anno feature ids: PRO_0000104081

83332:Rv1294
gene id: 83332:Rv1294
uniprot id: P9WPX1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ACT
up seq anno comments: Homoserine dehydrogenase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000066702

83332:Rv1650
gene id: 83332:Rv1650
uniprot id: P9WFU1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: B5
up seq anno comments: FDX-ACB
up seq anno comments: Phenylalanine--tRNA ligase beta subunit
up seq anno comments: tRNA-binding
up seq anno feature ids: PRO_0000126916

83332:Rv2486
gene id: 83332:Rv2486
uniprot id: P9WNN5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Probable enoyl-CoA hydratase EchA14
up seq anno feature ids: PRO_0000109343

83332:Rv3321c
gene id: 83332:Rv3321c
uniprot id: P9WJ17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative antitoxin VapB44
up seq anno feature ids: PRO_0000408084

83332:Rv1127c
gene id: 83332:Rv1127c
uniprot id: O06579
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PEP-utilising enzyme mobile
up seq anno comments: Pyruvate phosphate dikinase AMP/ATP-binding

83332:Rv2294
gene id: 83332:Rv2294
uniprot id: P9WQ83
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Putative cystathionine beta-lyase
up seq anno feature ids: PRO_0000163850

83332:Rv3147
gene id: 83332:Rv3147
uniprot id: P9WJH3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: NADH-quinone oxidoreductase subunit C
up seq anno feature ids: PRO_0000118670

83332:Rv2625c
gene id: 83332:Rv2625c
uniprot id: P9WHR1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: Helical
up seq anno comments: Putative zinc metalloprotease Rip3
up seq anno feature ids: PRO_0000392914

83332:Rv0020c
gene id: 83332:Rv0020c
uniprot id: P71590
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Abolishes phosphorylation by PknB.
up seq anno comments: Abolishes phosphorylation by PknB. Strong decrease in affinity for MviN.
up seq anno comments: Basic and acidic residues
up seq anno comments: Decrease in affinity for MviN.
up seq anno comments: Disordered
up seq anno comments: Does not affect affinity for MviN.
up seq anno comments: FHA
up seq anno comments: FHA domain-containing protein FhaA
up seq anno comments: Lack of phosphorylation.
up seq anno comments: Phosphothreonine
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000419664

83332:Rv0979A
gene id: 83332:Rv0979A
uniprot id: P9WH99
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL32
up seq anno feature ids: PRO_0000172373

83332:Rv2949c
gene id: 83332:Rv2949c
uniprot id: P9WIC5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Chorismate pyruvate-lyase
up seq anno feature ids: PRO_0000240510

83332:Rv2055c
gene id: 83332:Rv2055c
uniprot id: P9WH47
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein bS18B
up seq anno feature ids: PRO_0000111191

83332:Rv3450c
gene id: 83332:Rv3450c
uniprot id: P9WNR1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-4 secretion system ATPase EccB4
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393231

83332:Rv1026
gene id: 83332:Rv1026
uniprot id: P96374
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Exopolyphosphatase 2
up seq anno feature ids: PRO_0000440100

83332:Rv0163
gene id: 83332:Rv0163
uniprot id: O07408
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thioesterase

83332:Rv0688
gene id: 83332:Rv0688
uniprot id: P95034
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD/NAD(P)-binding
up seq anno comments: Reductase C-terminal

83332:Rv1519
gene id: 83332:Rv1519
uniprot id: P9WLV7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1519
up seq anno feature ids: PRO_0000103866

83332:Rv3269
gene id: 83332:Rv3269
uniprot id: P96874
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0515
gene id: 83332:Rv0515
uniprot id: O33360
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HNH nuclease
up seq anno comments: Polar residues

83332:Rv1691
gene id: 83332:Rv1691
uniprot id: O33193
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv1343c
gene id: 83332:Rv1343c
uniprot id: P9WK51
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LprD
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000103817

83332:Rv2180c
gene id: 83332:Rv2180c
uniprot id: O53514
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0492A
gene id: 83332:Rv0492A
uniprot id: Q6MX36
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2003c
gene id: 83332:Rv2003c
uniprot id: P9WJZ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2003c
up seq anno feature ids: PRO_0000103930

83332:Rv0107c
gene id: 83332:Rv0107c
uniprot id: P9WPS5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Probable cation-transporting ATPase I
up seq anno feature ids: PRO_0000046347

83332:Rv2316
gene id: 83332:Rv2316
uniprot id: P71896
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv3177
gene id: 83332:Rv3177
uniprot id: O53327
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv1827
gene id: 83332:Rv1827
uniprot id: P9WJA9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decreases ability to bind to and regulate the activities of Gdh and GltB, but does not affect ability to inhibit Kgd.
up seq anno comments: Does not affect phosphorylation by PknG.
up seq anno comments: FHA
up seq anno comments: Glycogen accumulation regulator GarA
up seq anno comments: Lack of phosphorylation by PknG.
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphothreonine; by PknB
up seq anno comments: Phosphothreonine; by PknG
up seq anno comments: Removed
up seq anno feature ids: PRO_0000103902

83332:Rv2672
gene id: 83332:Rv2672
uniprot id: P71969
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
up seq anno feature ids: PRO_5038718123

83332:Rv2148c
gene id: 83332:Rv2148c
uniprot id: P9WFQ7
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Pyridoxal phosphate homeostasis protein
up seq anno feature ids: PRO_0000163203

83332:Rv3862c
gene id: 83332:Rv3862c
uniprot id: P9WF37
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mass
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: Fully oxidized recombinant protein tagged at both termini.
up seq anno comments: Fully reduced recombinant protein tagged at both termini.
up seq anno comments: Probable transcriptional regulator WhiB6
up seq anno feature ids: PRO_0000420386

83332:Rv1606
gene id: 83332:Rv1606
uniprot id: P9WMM7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Phosphoribosyl-AMP cyclohydrolase
up seq anno feature ids: PRO_0000136486

83332:Rv1041c
gene id: 83332:Rv1041c
uniprot id: P96360
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Transposase IS4-like

83332:Rv0510
gene id: 83332:Rv0510
uniprot id: P9WMP3
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Porphobilinogen deaminase
up seq anno comments: S-(dipyrrolylmethanemethyl)cysteine
up seq anno feature ids: PRO_0000142960

83332:Rv0338c
gene id: 83332:Rv0338c
uniprot id: O33268
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 4Fe-4S ferredoxin-type
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv1192
gene id: 83332:Rv1192
uniprot id: O05294
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2931
gene id: 83332:Rv2931
uniprot id: P9WQE7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Acyltransferase
up seq anno comments: Beta-ketoacyl reductase
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier 1
up seq anno comments: Carrier 2
up seq anno comments: Disordered
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: For malonyltransferase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: N-acetylthreonine
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Phenolphthiocerol/phthiocerol polyketide synthase subunit A
up seq anno comments: Polar residues
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Removed
up seq anno feature ids: PRO_0000180301

83332:Rv3775
gene id: 83332:Rv3775
uniprot id: P72041
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Beta-lactamase-related

83332:Rv1008
gene id: 83332:Rv1008
uniprot id: O08343
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized metal-dependent hydrolase TatD
up seq anno feature ids: PRO_0000434887

83332:Rv1849
gene id: 83332:Rv1849
uniprot id: P9WFE9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Urease subunit beta
up seq anno feature ids: PRO_0000067579

83332:Rv2396
gene id: 83332:Rv2396
uniprot id: Q79FE6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0809
gene id: 83332:Rv0809
uniprot id: I6Y4V6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PurM-like C-terminal
up seq anno comments: PurM-like N-terminal

83332:Rv3191c
gene id: 83332:Rv3191c
uniprot id: O53337
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Integrase catalytic

83332:Rv1304
gene id: 83332:Rv1304
uniprot id: P9WPV7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ATP synthase subunit a
up seq anno comments: Helical
up seq anno feature ids: PRO_0000082063

83332:Rv1661
gene id: 83332:Rv1661
uniprot id: P94996
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv2843
gene id: 83332:Rv2843
uniprot id: I6YAE2
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3335c
gene id: 83332:Rv3335c
uniprot id: O53385
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1140
gene id: 83332:Rv1140
uniprot id: O06540
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv1963c
gene id: 83332:Rv1963c
uniprot id: P95251
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type 1
up seq anno comments: HTH tetR-type 2
up seq anno comments: Transcriptional repressor Mce3R
up seq anno feature ids: PRO_0000438536

83332:Rv3157
gene id: 83332:Rv3157
uniprot id: P9WIW5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: NADH-quinone oxidoreductase subunit M
up seq anno feature ids: PRO_0000118044

83332:Rv0030
gene id: 83332:Rv0030
uniprot id: P9WM95
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0030
up seq anno feature ids: PRO_0000103648

83332:Rv1781c
gene id: 83332:Rv1781c
uniprot id: P9WK23
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: 4-alpha-glucanotransferase
up seq anno feature ids: PRO_0000170127

83332:Rv2959c
gene id: 83332:Rv2959c
uniprot id: P9WIM5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Rhamnosyl O-methyltransferase
up seq anno feature ids: PRO_0000305181

83332:Rv0208c
gene id: 83332:Rv0208c
uniprot id: P9WFY9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: tRNA (guanine-N(7)-)-methyltransferase
up seq anno feature ids: PRO_0000171361

83332:Rv3462c
gene id: 83332:Rv3462c
uniprot id: P9WKK3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: S1-like
up seq anno comments: Translation initiation factor IF-1
up seq anno feature ids: PRO_0000095828

83332:Rv0698
gene id: 83332:Rv0698
uniprot id: P95044
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3834c
gene id: 83332:Rv3834c
uniprot id: P9WFT7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-acetyllysine
up seq anno comments: Serine--tRNA ligase
up seq anno feature ids: PRO_0000122086

83332:Rv0176
gene id: 83332:Rv0176
uniprot id: O07420
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: RDD

83332:Rv2791c
gene id: 83332:Rv2791c
uniprot id: O33333
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Cas12f1-like TNB
up seq anno comments: Disordered
up seq anno comments: Probable transposase IS891/IS1136/IS1341
up seq anno comments: Transposase putative helix-turn-helix

83332:Rv3656c
gene id: 83332:Rv3656c
uniprot id: O69624
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3279c
gene id: 83332:Rv3279c
uniprot id: I6YFP0
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: BPL/LPL catalytic
up seq anno comments: Biotin--[acetyl-CoA-carboxylase] ligase
up seq anno comments: Loss of activity.
up seq anno feature ids: PRO_0000452501

83332:Rv0529
gene id: 83332:Rv0529
uniprot id: O06393
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Cytochrome c assembly protein
up seq anno comments: Helical

83332:Rv0001
gene id: 83332:Rv0001
uniprot id: P9WNW3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Chromosomal replication initiator protein DnaA
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000114218

83332:Rv2368c
gene id: 83332:Rv2368c
uniprot id: P9WIA3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PhoH-like protein
up seq anno feature ids: PRO_0000201158

83332:Rv2190c
gene id: 83332:Rv2190c
uniprot id: P9WHU3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: NlpC/P60
up seq anno comments: Nucleophile
up seq anno comments: Pro residues
up seq anno comments: Probable endopeptidase Rv2190c
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000109873

83332:Rv0589
gene id: 83332:Rv0589
uniprot id: Q79FY7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv0820
gene id: 83332:Rv0820
uniprot id: P9WQL1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Phosphate import ATP-binding protein PstB 1
up seq anno feature ids: PRO_0000092849

83332:Rv1198
gene id: 83332:Rv1198
uniprot id: P9WNJ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxL
up seq anno feature ids: PRO_0000167805

83332:Rv2372c
gene id: 83332:Rv2372c
uniprot id: P9WGX1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Ribosomal RNA small subunit methyltransferase E
up seq anno feature ids: PRO_0000176213

83332:Rv1161
gene id: 83332:Rv1161
uniprot id: P9WJQ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: 4Fe-4S Mo/W bis-MGD-type
up seq anno comments: N-acetylthreonine
up seq anno comments: Nitrate reductase alpha subunit
up seq anno comments: Removed
up seq anno feature ids: PRO_0000393357

83332:Rv0118c
gene id: 83332:Rv0118c
uniprot id: O53639
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thiamine pyrophosphate enzyme N-terminal TPP-binding
up seq anno comments: Thiamine pyrophosphate enzyme TPP-binding
up seq anno comments: Thiamine pyrophosphate enzyme central

83332:Rv2330c
gene id: 83332:Rv2330c
uniprot id: P9WK69
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppP
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018116

83332:Rv0647c
gene id: 83332:Rv0647c
uniprot id: P9WQI1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0647c
up seq anno feature ids: PRO_0000200735

83332:Rv2856
gene id: 83332:Rv2856
uniprot id: I6YEJ7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: 23% decrease of nickel uptake. Decreases or abolishes resistance against several antibiotics.
up seq anno comments: 65% decrease of nickel uptake. Decreases or abolishes resistance against several antibiotics.
up seq anno comments: 66% decrease of nickel uptake. Decreases or abolishes resistance against several antibiotics.
up seq anno comments: 92% decrease of nickel uptake. Decreases or abolishes resistance against several antibiotics.
up seq anno comments: Helical
up seq anno comments: Nickel transporter NicT
up seq anno feature ids: PRO_0000457478

83332:Rv1837c
gene id: 83332:Rv1837c
uniprot id: P9WK17
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cysteine sulfenic acid (-SOH)
up seq anno comments: Disordered
up seq anno comments: Malate synthase G
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000166889

83332:Rv2158c
gene id: 83332:Rv2158c
uniprot id: P9WJL3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Meso-diaminopimelate recognition motif
up seq anno comments: N6-carboxylysine
up seq anno comments: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
up seq anno feature ids: PRO_0000101913

83332:Rv2684
gene id: 83332:Rv2684
uniprot id: P9WPD9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized transporter Rv2684
up seq anno feature ids: PRO_0000172514

83332:Rv0788
gene id: 83332:Rv0788
uniprot id: P9WHL5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: Nucleophile
up seq anno comments: Phosphoribosylformylglycinamidine synthase subunit PurQ
up seq anno feature ids: PRO_0000100572

83332:Rv3874
gene id: 83332:Rv3874
uniprot id: B5TV88
uniprot id: P9WNK5
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Turn
up seq anno comments: Abolishes EsxB-EsxA heterodimer interaction with EccCb1 and EspA, maintains interaction with EccA2 and EccE2.
up seq anno comments: Abolishes EsxB-EsxA heterodimer interaction with EccCb1, maintains interaction with EspA, EccA2 and EccE2.
up seq anno comments: Abolishes EsxB-EsxA heterodimer interaction with EccCb1, weaker interaction with EspA, maintains interaction with EccA2 and EccE2.
up seq anno comments: Abolishes interaction with EccCb1, but not with EsxA.
up seq anno comments: Abolishes interaction with EccCb1, but not with EsxA. No change in stability, but loss of secretion.
up seq anno comments: Disordered
up seq anno comments: ESAT-6-like protein EsxB
up seq anno comments: N-acetylalanine
up seq anno comments: No change in stability.
up seq anno comments: Removed
up seq anno comments: Required for ESAT-6/CFP-10 complex to bind to host macrophage and monocytes
up seq anno feature ids: PRO_0000167796

83332:Rv2969c
gene id: 83332:Rv2969c
uniprot id: O33272
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Thioredoxin-like fold

83332:Rv0219
gene id: 83332:Rv0219
uniprot id: P96401
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2630
gene id: 83332:Rv2630
uniprot id: P9WQ03
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable protein archease
up seq anno feature ids: PRO_0000392933

83332:Rv2801c
gene id: 83332:Rv2801c
uniprot id: P71650
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Endoribonuclease MazF9
up seq anno feature ids: PRO_0000406309

83332:Rv2273
gene id: 83332:Rv2273
uniprot id: P9WLF3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2273
up seq anno feature ids: PRO_0000104001

83332:Rv0011c
gene id: 83332:Rv0011c
uniprot id: P9WP57
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cell division protein CrgA
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno feature ids: PRO_0000216814

83332:Rv2941
gene id: 83332:Rv2941
uniprot id: P9WQ59
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Important for substrate selectivity
up seq anno comments: Long-chain-fatty-acid--AMP ligase FadD28
up seq anno comments: No activity with lauric acid (C12 fatty acid) as substrate. Instead, it catalyzes activation of acetic acid (C2 fatty acid) as acetyl-AMP.
up seq anno comments: Shows substantial decrease (69%) in the activity with lauric acid (C12 fatty acid) as substrate but shows a 4-fold higher activity with the long chain fatty acyl capric acid (C10 fatty acid) as substrate.
up seq anno feature ids: PRO_0000406355

83332:Rv3824c
gene id: 83332:Rv3824c
uniprot id: P9WIK9
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 2'-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase PapA1
up seq anno comments: Loss of sulfolipid-1 (SL-1) production.
up seq anno feature ids: PRO_0000314658

83332:Rv1701
gene id: 83332:Rv1701
uniprot id: P9WF33
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Core-binding (CB)
up seq anno comments: O-(3'-phospho-DNA)-tyrosine intermediate
up seq anno comments: Tyr recombinase
up seq anno comments: Tyrosine recombinase XerD
up seq anno feature ids: PRO_0000095398

83332:Rv1018c
gene id: 83332:Rv1018c
uniprot id: P9WMN3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Bifunctional protein GlmU
up seq anno comments: Disordered
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Linker
up seq anno comments: N-acetylthreonine
up seq anno comments: N-acetyltransferase
up seq anno comments: Polar residues
up seq anno comments: Proton acceptor
up seq anno comments: Pyrophosphorylase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000233802

83332:Rv1859
gene id: 83332:Rv1859
uniprot id: P9WQL3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno comments: ABC transporter
up seq anno comments: Molybdenum import ATP-binding protein ModC
up seq anno comments: Mop
up seq anno feature ids: PRO_0000092565

83332:Rv2487c
gene id: 83332:Rv2487c
uniprot id: I6XEF1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno feature ids: PRO_5003706547

83332:Rv0485
gene id: 83332:Rv0485
uniprot id: P9WKV1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: Transcriptional regulator Rv0485
up seq anno feature ids: PRO_0000103687

83332:Rv3623
gene id: 83332:Rv3623
uniprot id: I6X7X3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno feature ids: PRO_5010310468

83332:Rv0130
gene id: 83332:Rv0130
uniprot id: P9WNP3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 27% loss of activity.
up seq anno comments: 3-hydroxyacyl-thioester dehydratase Z
up seq anno comments: Important for catalytic activity
up seq anno comments: MaoC-like
up seq anno comments: Total loss of activity.
up seq anno comments: Transition state stabilizer
up seq anno comments: in homodimeric partner
up seq anno feature ids: PRO_0000262761

83332:Rv1314c
gene id: 83332:Rv1314c
uniprot id: P9WP99
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Corrinoid adenosyltransferase
up seq anno feature ids: PRO_0000103798

83332:Rv1673c
gene id: 83332:Rv1673c
uniprot id: O53920
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transglutaminase-like

83332:Rv0313
gene id: 83332:Rv0313
uniprot id: P9WL03
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv0313
up seq anno feature ids: PRO_0000403671

83332:Rv1151c
gene id: 83332:Rv1151c
uniprot id: P9WGG3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Deacetylase sirtuin-type
up seq anno comments: NAD-dependent protein deacylase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000110331

83332:Rv1974
gene id: 83332:Rv1974
uniprot id: O53975
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF732

83332:Rv0042c
gene id: 83332:Rv0042c
uniprot id: P71699
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HTH marR-type

83332:Rv1804c
gene id: 83332:Rv1804c
uniprot id: O53953
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: DUF732
up seq anno feature ids: PRO_5010172042

83332:Rv2641
gene id: 83332:Rv2641
uniprot id: P9WIR5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno comments: Cadmium-induced protein CadI
up seq anno comments: Removed
up seq anno comments: VOC
up seq anno feature ids: PRO_0000089275

83332:Rv3473c
gene id: 83332:Rv3473c
uniprot id: O06338
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv0708
gene id: 83332:Rv0708
uniprot id: P9WHD5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein uL16
up seq anno feature ids: PRO_0000062138

83332:Rv3844
gene id: 83332:Rv3844
uniprot id: P96234
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS110-like N-terminal

83332:Rv2471
gene id: 83332:Rv2471
uniprot id: O53198
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Glycosyl hydrolase family 13 catalytic

83332:Rv3667
gene id: 83332:Rv3667
uniprot id: P9WQD1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: Acetyl-coenzyme A synthetase
up seq anno comments: Complete loss of acetyl-coenzyme A synthetase activity.
up seq anno comments: N-acetylserine
up seq anno comments: N6-acetyllysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000208369

83332:Rv3289c
gene id: 83332:Rv3289c
uniprot id: P96894
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0541c
gene id: 83332:Rv0541c
uniprot id: O06407
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2853
gene id: 83332:Rv2853
uniprot id: Q6MX26
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv2438A
gene id: 83332:Rv2438A
uniprot id: Q79FD9
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1373
gene id: 83332:Rv1373
uniprot id: P9WGB9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glycolipid sulfotransferase Rv1373
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000315390

83332:Rv0742
gene id: 83332:Rv0742
uniprot id: I6Y8K5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS8
up seq anno feature ids: PRO_5008166656

83332:Rv0835
gene id: 83332:Rv0835
uniprot id: O53846
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PknH-like extracellular
up seq anno feature ids: PRO_5038827710

83332:Rv1209
gene id: 83332:Rv1209
uniprot id: O05310
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2382c
gene id: 83332:Rv2382c
uniprot id: P71718
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv2027c
gene id: 83332:Rv2027c
uniprot id: P9WGK1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-binding domain
up seq anno comments: GAF 1
up seq anno comments: GAF 2
up seq anno comments: Heme iron oxidizes more easily.
up seq anno comments: Histidine kinase
up seq anno comments: No autophosphorylation, no phosphate transfer to DevR (DosR).
up seq anno comments: No autophosphorylation.
up seq anno comments: Oxygen sensor histidine kinase response regulator DosT
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000392624

83332:Rv2867c
gene id: 83332:Rv2867c
uniprot id: I6XFI7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase

83332:Rv0658c
gene id: 83332:Rv0658c
uniprot id: O06781
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1494
gene id: 83332:Rv1494
uniprot id: P9WJ91
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Probable antitoxin MazE4
up seq anno feature ids: PRO_0000103858

83332:Rv2697c
gene id: 83332:Rv2697c
uniprot id: P9WNS5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Deoxyuridine 5'-triphosphate nucleotidohydrolase
up seq anno feature ids: PRO_0000182884

83332:Rv0801
gene id: 83332:Rv0801
uniprot id: O06633
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: VOC

83332:Rv1318c
gene id: 83332:Rv1318c
uniprot id: P9WQ33
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Guanylate cyclase
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1318c
up seq anno feature ids: PRO_0000195752

83332:Rv3541c
gene id: 83332:Rv3541c
uniprot id: I6XHI0
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase beta subunit
up seq anno comments: Loss of activity. Still forms heterotetramers.
up seq anno comments: Retains 2-4% of activity. Still forms heterotetramers.
up seq anno feature ids: PRO_0000452240

83332:Rv2503c
gene id: 83332:Rv2503c
uniprot id: P9WPW3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit B
up seq anno feature ids: PRO_0000157923

83332:Rv2979c
gene id: 83332:Rv2979c
uniprot id: I6XFU1
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: O-(5'-phospho-DNA)-serine intermediate
up seq anno comments: Resolvase/invertase-type recombinase catalytic

83332:Rv0229c
gene id: 83332:Rv0229c
uniprot id: L0T5V6
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC51
up seq anno feature ids: PRO_0000430096

83332:Rv3356c
gene id: 83332:Rv3356c
uniprot id: P9WG81
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Bifunctional protein FolD
up seq anno feature ids: PRO_0000268404

83332:Rv2323c
gene id: 83332:Rv2323c
uniprot id: P71889
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: N(G),N(G)-dimethylarginine dimethylaminohydrolase
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000443949

83332:Rv1462
gene id: 83332:Rv1462
uniprot id: P9WFP5
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: UPF0051 protein Rv1462
up seq anno feature ids: PRO_0000147386

83332:Rv2813
gene id: 83332:Rv2813
uniprot id: I6XFD1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA+ ATPase

83332:Rv2286c
gene id: 83332:Rv2286c
uniprot id: P9WLE7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2286c
up seq anno feature ids: PRO_0000104006

83332:Rv2996c
gene id: 83332:Rv2996c
uniprot id: P9WNX3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ACT
up seq anno comments: D-3-phosphoglycerate dehydrogenase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000076005

83332:Rv2951c
gene id: 83332:Rv2951c
uniprot id: P9WIB7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Sequence Conflict
up seq anno comments: Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase
up seq anno feature ids: PRO_0000309352

83332:Rv1713
gene id: 83332:Rv1713
uniprot id: P9WNL3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: EngA-type G 1
up seq anno comments: EngA-type G 2
up seq anno comments: GTPase Der
up seq anno comments: KH-like
up seq anno feature ids: PRO_0000179017

83332:Rv0357c
gene id: 83332:Rv0357c
uniprot id: P9WHN3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Adenylosuccinate synthetase
up seq anno comments: N-acetylproline
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000095199

83332:Rv3482c
gene id: 83332:Rv3482c
uniprot id: I6YG92
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: DUF2510
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0679c
gene id: 83332:Rv0679c
uniprot id: I6WZ30
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno feature ids: PRO_5039535522

83332:Rv0180c
gene id: 83332:Rv0180c
uniprot id: O07424
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF3533
up seq anno comments: Helical

83332:Rv2612c
gene id: 83332:Rv2612c
uniprot id: P9WPG7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 2-fold decrease in catalytic activity.
up seq anno comments: Almost loss of catalytic activity.
up seq anno comments: Helical
up seq anno comments: Large decrease in catalytic activity.
up seq anno comments: No change in catalytic activity.
up seq anno comments: Phosphatidylinositol phosphate synthase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000393108

83332:Rv2394
gene id: 83332:Rv2394
uniprot id: P71750
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno feature ids: PRO_5038915361

83332:Rv0496
gene id: 83332:Rv0496
uniprot id: P9WHV5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Exopolyphosphatase 1
up seq anno feature ids: PRO_0000194307

83332:Rv3633
gene id: 83332:Rv3633
uniprot id: P9WI89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3633
up seq anno feature ids: PRO_0000215236

83332:Rv1358
gene id: 83332:Rv1358
uniprot id: Q11028
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH luxR-type

83332:Rv0140
gene id: 83332:Rv0140
uniprot id: P96817
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF427

83332:Rv1324
gene id: 83332:Rv1324
uniprot id: P9WG61
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: Thioredoxin
up seq anno comments: Uncharacterized protein Rv1324
up seq anno feature ids: PRO_0000014093

83332:Rv1683
gene id: 83332:Rv1683
uniprot id: O33185
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv0324
gene id: 83332:Rv0324
uniprot id: O08446
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: H-T-H motif
up seq anno comments: HTH arsR-type
up seq anno comments: HTH-type transcriptional regulator Rv0324
up seq anno comments: Rhodanese
up seq anno feature ids: PRO_0000458267

83332:Rv3885c
gene id: 83332:Rv3885c
uniprot id: P9WJE7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-2 secretion system protein EccE2
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393870

83332:Rv1986
gene id: 83332:Rv1986
uniprot id: P9WK31
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Lysine exporter LysE
up seq anno feature ids: PRO_0000103916

83332:Rv3622c
gene id: 83332:Rv3622c
uniprot id: I6YGS7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv2335
gene id: 83332:Rv2335
uniprot id: P95231
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Serine acetyltransferase
up seq anno feature ids: PRO_0000401135

83332:Rv1819c
gene id: 83332:Rv1819c
uniprot id: P9WQI9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Helical
up seq anno comments: Hydrophilic compounds import ATP-binding/permease protein BacA
up seq anno comments: Loss of cobalamin transport. Shows background ATPase activity.
up seq anno feature ids: PRO_0000093265

83332:Rv2653c
gene id: 83332:Rv2653c
uniprot id: P9WJ13
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Toxin Rv2653c
up seq anno feature ids: PRO_0000406887

83332:Rv3527
gene id: 83332:Rv3527
uniprot id: I6XHG6
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2296
gene id: 83332:Rv2296
uniprot id: P9WMS3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1
up seq anno comments: Haloalkane dehalogenase 1
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000216767

83332:Rv0719
gene id: 83332:Rv0719
uniprot id: P9WH81
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL6
up seq anno feature ids: PRO_0000131062

83332:Rv3854c
gene id: 83332:Rv3854c
uniprot id: P9WNF9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno comments: ETH-resistant.
up seq anno comments: FAD-containing monooxygenase EthA
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000398581

83332:Rv2483c
gene id: 83332:Rv2483c
uniprot id: I6YDI9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv3301c
gene id: 83332:Rv3301c
uniprot id: P9WI97
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Phosphate-specific transport system accessory protein PhoU homolog 1
up seq anno feature ids: PRO_0000155171

83332:Rv0551c
gene id: 83332:Rv0551c
uniprot id: O06417
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Medium/long-chain-fatty-acid--CoA ligase FadD8
up seq anno feature ids: PRO_0000451307

83332:Rv3308
gene id: 83332:Rv3308
uniprot id: O53360
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alpha-D-phosphohexomutase C-terminal
up seq anno comments: Alpha-D-phosphohexomutase alpha/beta/alpha

83332:Rv1383
gene id: 83332:Rv1383
uniprot id: P9WPK5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CPSase
up seq anno comments: Carbamoyl-phosphate synthase small chain
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000112296

83332:Rv0017c
gene id: 83332:Rv0017c
uniprot id: P9WN99
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Can rescue the moenomycin sensitivity phenotype and the aberrant short-length phenotype of the deletion mutant.
up seq anno comments: Can rescue the moenomycin sensitivity phenotype of the deletion mutant, but cannot rescue the aberrant short-length phenotype.
up seq anno comments: Helical
up seq anno comments: Peptidoglycan glycosyltransferase RodA
up seq anno comments: Phosphothreonine
up seq anno feature ids: PRO_0000062710

83332:Rv3131
gene id: 83332:Rv3131
uniprot id: P9WIZ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Putative NAD(P)H nitroreductase Rv3131
up seq anno comments: Removed
up seq anno feature ids: PRO_0000392943

83332:Rv0846c
gene id: 83332:Rv0846c
uniprot id: I6WZK7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno comments: Lack of activity.
up seq anno comments: Multicopper oxidase MmcO
up seq anno comments: Plastocyanin-like
up seq anno comments: Slight decrease in activity.
up seq anno comments: Tat-type signal
up seq anno feature ids: PRO_0000433098

83332:Rv1220c
gene id: 83332:Rv1220c
uniprot id: P9WJZ7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Disordered
up seq anno comments: Probable O-methyltransferase Rv1220c
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000380105

83332:Rv2598
gene id: 83332:Rv2598
uniprot id: P9WL71
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2598
up seq anno feature ids: PRO_0000104067

83332:Rv0668
gene id: 83332:Rv0668
uniprot id: P9WGY7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: DNA-directed RNA polymerase subunit beta'
up seq anno feature ids: PRO_0000067765

83332:Rv1506c
gene id: 83332:Rv1506c
uniprot id: P71785
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative methyltransferase Rv1506c
up seq anno feature ids: PRO_0000438346

83332:Rv2707
gene id: 83332:Rv2707
uniprot id: I6YE67
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1329c
gene id: 83332:Rv1329c
uniprot id: P9WMR5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: DEAH box
up seq anno comments: Helicase ATP-binding
up seq anno comments: Probable ATP-dependent helicase DinG homolog
up seq anno feature ids: PRO_0000102003

83332:Rv3551
gene id: 83332:Rv3551
uniprot id: P9WPW1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cholesterol ring-cleaving hydrolase IpdA subunit
up seq anno feature ids: PRO_0000157928

83332:Rv2177c
gene id: 83332:Rv2177c
uniprot id: O53511
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS116/IS110/IS902 C-terminal

83332:Rv2989
gene id: 83332:Rv2989
uniprot id: O53238
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH iclR-type
up seq anno comments: IclR-ED

83332:Rv0240
gene id: 83332:Rv0240
uniprot id: P9WF87
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC24
up seq anno feature ids: PRO_0000407883

83332:Rv3366
gene id: 83332:Rv3366
uniprot id: O50394
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: tRNA/rRNA methyltransferase SpoU type

83332:Rv2000
gene id: 83332:Rv2000
uniprot id: P9WLN7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2000
up seq anno feature ids: PRO_0000103927

83332:Rv1474c
gene id: 83332:Rv1474c
uniprot id: O53165
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Cannot bind DNA; when associated with A-45 and A-50.
up seq anno comments: Cannot bind DNA; when associated with A-45 and A-55.
up seq anno comments: Cannot bind DNA; when associated with A-50 and A-55.
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional repressor Rv1474c
up seq anno feature ids: PRO_0000447327

83332:Rv3173c
gene id: 83332:Rv3173c
uniprot id: O53323
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3110
gene id: 83332:Rv3110
uniprot id: Q6MX13
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3677c
gene id: 83332:Rv3677c
uniprot id: I6XHY3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv0902c
gene id: 83332:Rv0902c
uniprot id: P9WGK7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Sensor-type histidine kinase PrrB
up seq anno feature ids: PRO_0000074854

83332:Rv3492c
gene id: 83332:Rv3492c
uniprot id: I6YGA5
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2406c
gene id: 83332:Rv2406c
uniprot id: P71737
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CBS

83332:Rv2741
gene id: 83332:Rv2741
uniprot id: Q79FB3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS47
up seq anno feature ids: PRO_5004287628

83332:Rv0190
gene id: 83332:Rv0190
uniprot id: O07434
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: Copper-sensing transcriptional repressor RicR
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Unresponsive to copper.
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000433099

83332:Rv0507
gene id: 83332:Rv0507
uniprot id: P9WJV7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport protein MmpL2
up seq anno feature ids: PRO_0000103563

83332:Rv3645
gene id: 83332:Rv3645
uniprot id: I6X7Z3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Guanylate cyclase
up seq anno comments: HAMP
up seq anno comments: Helical

83332:Rv1023
gene id: 83332:Rv1023
uniprot id: P9WNL1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Enolase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: covalent; in inhibited form
up seq anno feature ids: PRO_0000133932

83332:Rv0334
gene id: 83332:Rv0334
uniprot id: P9WH13
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decreases activity and negatively affects cell wall formation. Attenuates virulence in a macrophage model with promoted cytokine production in host cells.
up seq anno comments: Glucose-1-phosphate thymidylyltransferase
up seq anno comments: Phosphothreonine; by PknB
up seq anno comments: Significant loss of phosphorylation. Lack of phosphorylation; when associated with A-54. Decreases activity and negatively affects cell wall formation.
up seq anno comments: Small decrease in phosphorylation.
up seq anno comments: Small decrease in phosphorylation. Lack of phosphorylation; when associated with A-12.
up seq anno feature ids: PRO_0000395347

83332:Rv3049c
gene id: 83332:Rv3049c
uniprot id: I6Y2E2
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1179c
gene id: 83332:Rv1179c
uniprot id: O50435
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helicase ATP-binding

83332:Rv2032
gene id: 83332:Rv2032
uniprot id: P9WIZ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative NAD(P)H nitroreductase acg
up seq anno feature ids: PRO_0000392626

83332:Rv0811c
gene id: 83332:Rv0811c
uniprot id: I6X9V3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Aminomethyltransferase folate-binding

83332:Rv2524c
gene id: 83332:Rv2524c
uniprot id: P95029
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv3746c
gene id: 83332:Rv3746c
uniprot id: Q79FA1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv1996
gene id: 83332:Rv1996
uniprot id: P9WLP1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Universal stress protein Rv1996
up seq anno feature ids: PRO_0000103924

83332:Rv0993
gene id: 83332:Rv0993
uniprot id: O05576
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nucleotidyl transferase

83332:Rv1485
gene id: 83332:Rv1485
uniprot id: P9WNE3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Coproporphyrin III ferrochelatase
up seq anno feature ids: PRO_0000175167

83332:Rv1829
gene id: 83332:Rv1829
uniprot id: P9WLR5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: BFN
up seq anno comments: Uncharacterized protein Rv1829
up seq anno feature ids: PRO_0000103904

83332:Rv2346c
gene id: 83332:Rv2346c
uniprot id: P9WNI7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno comments: ESAT-6-like protein EsxO
up seq anno feature ids: PRO_0000167814

83332:Rv0452
gene id: 83332:Rv0452
uniprot id: O53737
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv2495c
gene id: 83332:Rv2495c
uniprot id: O06159
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex
up seq anno comments: Lipoyl-binding
up seq anno comments: N6-lipoyllysine
up seq anno comments: Peripheral subunit-binding (PSBD)
up seq anno feature ids: PRO_0000420520

83332:Rv2994
gene id: 83332:Rv2994
uniprot id: P9WJW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter Rv2994
up seq anno feature ids: PRO_0000390686

83332:Rv3318
gene id: 83332:Rv3318
uniprot id: O53370
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: FAD-dependent oxidoreductase 2 FAD binding
up seq anno comments: Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
up seq anno comments: Proton acceptor
up seq anno comments: Tele-8alpha-FAD histidine

83332:Rv2961
gene id: 83332:Rv2961
uniprot id: P95131
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Transposase IS4-like

83332:Rv0210
gene id: 83332:Rv0210
uniprot id: P96392
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1399c
gene id: 83332:Rv1399c
uniprot id: P9WK87
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Motif
up seq anno comments: Carboxylesterase NlhH
up seq anno comments: Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000419169

83332:Rv0027
gene id: 83332:Rv0027
uniprot id: P9WM99
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0027
up seq anno feature ids: PRO_0000103644

83332:Rv3143
gene id: 83332:Rv3143
uniprot id: P9WGL7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Removed
up seq anno comments: Response regulatory
up seq anno comments: Uncharacterized response regulatory protein Rv3143
up seq anno feature ids: PRO_0000403682

83332:Rv0858c
gene id: 83332:Rv0858c
uniprot id: P9WPZ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable N-succinyldiaminopimelate aminotransferase DapC
up seq anno feature ids: PRO_0000414591

83332:Rv2610c
gene id: 83332:Rv2610c
uniprot id: P9WMZ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Important for catalytic activity
up seq anno comments: Phosphatidyl-myo-inositol mannosyltransferase
up seq anno feature ids: PRO_0000080302

83332:Rv1230c
gene id: 83332:Rv1230c
uniprot id: O86313
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Transglycosylase SLT

83332:Rv0848
gene id: 83332:Rv0848
uniprot id: Q79FV4
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: 10-fold decrease in the specificity constant for thiosulfate compared to wild-type enzyme but little change in the specificity constant for the substrate OPS.
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: S-sulfocysteine synthase
up seq anno feature ids: PRO_0000401201

83332:Rv2042c
gene id: 83332:Rv2042c
uniprot id: O53486
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nuclear transport factor 2

83332:Rv1516c
gene id: 83332:Rv1516c
uniprot id: P71795
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Glycosyltransferase 2-like

83332:Rv2007c
gene id: 83332:Rv2007c
uniprot id: P9WNE7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 4Fe-4S ferredoxin-type
up seq anno comments: Ferredoxin
up seq anno feature ids: PRO_0000159099

83332:Rv1339
gene id: 83332:Rv1339
uniprot id: P9WGC1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1339
up seq anno feature ids: PRO_0000192688

83332:Rv3562
gene id: 83332:Rv3562
uniprot id: I6YGH7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv2187
gene id: 83332:Rv2187
uniprot id: O53521
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Long-chain-fatty-acid--CoA ligase FadD15
up seq anno feature ids: PRO_0000406784

83332:Rv0536
gene id: 83332:Rv0536
uniprot id: L7N670
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD-dependent epimerase/dehydratase

83332:Rv1839c
gene id: 83332:Rv1839c
uniprot id: P9WJ51
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB13
up seq anno feature ids: PRO_0000408060

83332:Rv3001c
gene id: 83332:Rv3001c
uniprot id: P9WKJ7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: KARI C-terminal knotted
up seq anno comments: KARI N-terminal Rossmann
up seq anno comments: Ketol-acid reductoisomerase (NADP(+))
up seq anno comments: Removed
up seq anno feature ids: PRO_0000151329

83332:Rv0250c
gene id: 83332:Rv0250c
uniprot id: O53672
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: Uncharacterized protein Rv0250c
up seq anno feature ids: PRO_0000403670

83332:Rv3378c
gene id: 83332:Rv3378c
uniprot id: P9WJ61
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes transferase activity.
up seq anno comments: Abolishes transferase activity. Decrease in TOH production. Almost loss of iso-TOH production.
up seq anno comments: Decrease in TOH production and almost loss of iso-TOH production. Almost loss of TOH and TOH production; when associated with F-51.
up seq anno comments: Does not affect TOH production. Strong decrease in iso-TOH production.
up seq anno comments: Significant decrease in phosphatase activity. Loss of phosphatase activity; when associated with N-81 or N-82.
up seq anno comments: Significant decrease in phosphatase activity. Loss of phosphatase activity; when associated with N-81 or N-85.
up seq anno comments: Significant decrease in phosphatase activity. Loss of phosphatase activity; when associated with N-82 or N-85.
up seq anno comments: Strong decrease in TOH and iso-TOH production. Almost loss of TOH and TOH production; when associated with F-90.
up seq anno comments: Tuberculosinyl adenosine transferase
up seq anno feature ids: PRO_0000416456

83332:Rv2011c
gene id: 83332:Rv2011c
uniprot id: P9WLM5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv2011c
up seq anno feature ids: PRO_0000014118

83332:Rv2835c
gene id: 83332:Rv2835c
uniprot id: I6XFF3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv2840c
gene id: 83332:Rv2840c
uniprot id: I6XFF7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: YlxR

83332:Rv3159c
gene id: 83332:Rv3159c
uniprot id: Q6MX04
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PPE

83332:Rv0912
gene id: 83332:Rv0912
uniprot id: O05904
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2301
gene id: 83332:Rv2301
uniprot id: P9WP41
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Signal Peptide
up seq anno comments: Nucleophile
up seq anno comments: Probable carboxylesterase Culp2
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000006449

83332:Rv3859c
gene id: 83332:Rv3859c
uniprot id: P96218
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: For GATase activity
up seq anno comments: Glutamate synthase [NADPH] large chain
up seq anno comments: Glutamine amidotransferase type-2
up seq anno feature ids: PRO_0000419545

83332:Rv0377
gene id: 83332:Rv0377
uniprot id: P9WMF7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH lysR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0377
up seq anno feature ids: PRO_0000105811

83332:Rv1240
gene id: 83332:Rv1240
uniprot id: P9WK13
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Malate dehydrogenase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000113380

83332:Rv2417c
gene id: 83332:Rv2417c
uniprot id: P9WP05
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: DegV
up seq anno comments: DegV domain-containing protein Rv2417c
up seq anno feature ids: PRO_0000209778

83332:Rv0200
gene id: 83332:Rv0200
uniprot id: O53651
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3658c
gene id: 83332:Rv3658c
uniprot id: I6Y479
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Type II secretion system protein GspF

83332:Rv1033c
gene id: 83332:Rv1033c
uniprot id: L7N689
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: 4-aspartylphosphate
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Response regulatory
up seq anno comments: Transcriptional regulatory protein TrcR
up seq anno feature ids: PRO_0000451063

83332:Rv3059
gene id: 83332:Rv3059
uniprot id: P9WPM7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylalanine
up seq anno comments: Putative cytochrome P450 136
up seq anno comments: Removed
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052295

83332:Rv0862c
gene id: 83332:Rv0862c
uniprot id: O53874
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helicase XPB/Ssl2 N-terminal

83332:Rv1698
gene id: 83332:Rv1698
uniprot id: P9WJ83
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Copper transporter MctB
up seq anno feature ids: PRO_0000014105

83332:Rv1189
gene id: 83332:Rv1189
uniprot id: P9WGH3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: Probable ECF RNA polymerase sigma factor SigI
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4_2
up seq anno feature ids: PRO_0000423647

83332:Rv0822c
gene id: 83332:Rv0822c
uniprot id: I6WZI4
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Cell envelope-related transcriptional attenuator
up seq anno comments: Disordered
up seq anno comments: LytR/CpsA/Psr regulator C-terminal
up seq anno comments: Polar residues

83332:Rv2535c
gene id: 83332:Rv2535c
uniprot id: I6YDN6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Creatinase N-terminal
up seq anno comments: Peptidase M24

83332:Rv3875
gene id: 83332:Rv3875
uniprot id: P9WNK7
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 16% reduction in liposome disruption.
up seq anno comments: 40% reduction in liposome disruption. 80% reduction; when associated with 2-T--G-10.
up seq anno comments: 40% reduction in liposome disruption. 80% reduction; when associated with 86-T--A-95.
up seq anno comments: 40% reduction in liposome disruption. 88% reduction in liposome disruption; when associated with E-17. Reduced liposome disruption; when associated with T-38.
up seq anno comments: 6 kDa early secretory antigenic target
up seq anno comments: 88% reduction in liposome disruption; when associated with 25-T-A-26.
up seq anno comments: Abolishes EsxB-EsxA heterodimer interaction with EccCb1, maintains interaction with EspA, EccA2 and EccE2.
up seq anno comments: Bacteria no longer gain access to host cytoplasm via phagosomal rupture.
up seq anno comments: Cannot be overproduced and purified.
up seq anno comments: Does not restore virulence in an esxA deletion strain, decreased secretion of EsxA and EsxB.
up seq anno comments: Does not restore virulence in an esxA deletion strain, wild-type secretion of EsxA and EsxB (PubMed:16048998). Partially inhibits host TLR2-signaling (PubMed:17486091).
up seq anno comments: Does not restore virulence in an esxA deletion strain, wild-type secretion of EsxA and EsxB but no complex formed (PubMed:16048998). No effect on host TLR2-signaling.
up seq anno comments: Does not restore virulence in an esxA deletion strain, wild-type secretion of EsxA and EsxB.
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine; partial
up seq anno comments: NBD-linked protein does not fluoresce at acidic pH in presence of liposomes, this residue may face inwards in membranes away from lipids.
up seq anno comments: NBD-linked protein fluoresces at acidic pH in presence of liposomes, suggests this residue faces lipids.
up seq anno comments: NBD-linked protein moderately fluoresces at acidic pH in presence of liposomes, suggests this residue is partially within membrane.
up seq anno comments: No longer inhibits host TLR2-signaling (PubMed:17486091). Does not interact with host B2M, does not decrease B2M cell surface expression, no defects in antigen presentation (PubMed:25356553).
up seq anno comments: No longer inhibits host TLR2-signaling.
up seq anno comments: Not required for ESAT-6/CFP-10 complex to bind to host macrophage and monocytes
up seq anno comments: Partially restores virulence in an esxA deletion strain, wild-type secretion of EsxA and EsxB (PubMed:16048998). Partially inhibits host TLR2-signaling (PubMed:17486091).
up seq anno comments: Reduced liposome disruption; when associated with 25-T-A-26.
up seq anno comments: Removed
up seq anno comments: Wild-type virulence in an esxA deletion strain.
up seq anno comments: Wild-type virulence in an esxA deletion strain; protein should not be acetylated.
up seq anno feature ids: PRO_0000167793

83332:Rv1005c
gene id: 83332:Rv1005c
uniprot id: O05591
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Chorismate-utilising enzyme C-terminal

83332:Rv1496
gene id: 83332:Rv1496
uniprot id: P9WPZ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable GTPase Rv1496
up seq anno comments: Removed
up seq anno feature ids: PRO_0000157817

83332:Rv2361c
gene id: 83332:Rv2361c
uniprot id: P9WFF7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decaprenyl diphosphate synthase
up seq anno comments: Disordered
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000123641

83332:Rv2675c
gene id: 83332:Rv2675c
uniprot id: I6Y1G8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv3188
gene id: 83332:Rv3188
uniprot id: O53334
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable mycobacterial cidal antitoxin Rv3188
up seq anno feature ids: PRO_0000448604

83332:Rv0401
gene id: 83332:Rv0401
uniprot id: P95210
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3006
gene id: 83332:Rv3006
uniprot id: I6Y293
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Glucose/Sorbosone dehydrogenase
up seq anno comments: Pro residues
up seq anno feature ids: PRO_5039505219

83332:Rv3332
gene id: 83332:Rv3332
uniprot id: O53382
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Amidohydrolase-related
up seq anno comments: Proton donor/acceptor

83332:Rv3869
gene id: 83332:Rv3869
uniprot id: P9WNR7
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 2-fold increase in ATPase activity (residues 72-448 only).
up seq anno comments: 6-fold increase in ATPase activity (residues 106-463 only).
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion system ATPase EccB1
up seq anno comments: Helical
up seq anno comments: Loop A
up seq anno comments: Loop B
up seq anno comments: No ATPase activity (residues 106-480 only).
up seq anno comments: Periplasmic
up seq anno comments: Retains 40% ATPase activity (in residues 72-480).
up seq anno comments: Retains only 20% decrease ATPase activity (in residues 72-480); probably due to loss of secondary structure.
up seq anno comments: Structural repeat A1/1
up seq anno comments: Structural repeat A2/3
up seq anno comments: Structural repeat C1/2
up seq anno comments: Structural repeat C2/4
up seq anno feature ids: PRO_0000393228

83332:Rv0221
gene id: 83332:Rv0221
uniprot id: P9WKB7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv0221
up seq anno feature ids: PRO_0000222905

83332:Rv1409
gene id: 83332:Rv1409
uniprot id: P9WPH1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CMP/dCMP-type deaminase
up seq anno comments: Deaminase
up seq anno comments: Proton donor
up seq anno comments: Reductase
up seq anno comments: Riboflavin biosynthesis protein RibD
up seq anno feature ids: PRO_0000171723

83332:Rv0039c
gene id: 83332:Rv0039c
uniprot id: P9WM89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0039c
up seq anno feature ids: PRO_0000103656

83332:Rv3702c
gene id: 83332:Rv3702c
uniprot id: O69670
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase
up seq anno comments: Glutamine amidotransferase type-2
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000413650

83332:Rv3154
gene id: 83332:Rv3154
uniprot id: P95172
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3669
gene id: 83332:Rv3669
uniprot id: O69637
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv2622
gene id: 83332:Rv2622
uniprot id: I6XES4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase type 11

83332:Rv2861c
gene id: 83332:Rv2861c
uniprot id: P9WK19
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Methionine aminopeptidase 2
up seq anno feature ids: PRO_0000148948

83332:Rv0518
gene id: 83332:Rv0518
uniprot id: O33363
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: GDSL lipase Rv0518
up seq anno comments: Loss of activity.
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: Retains 15-20% of activity.
up seq anno comments: Retains 50-55% of activity.
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000448306

83332:Rv0949
gene id: 83332:Rv0949
uniprot id: P9WMQ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: ATP-dependent DNA helicase UvrD1
up seq anno comments: Disordered
up seq anno comments: Loss of ATPase and DNA unwinding, partially inhibits DNA strand exchange.
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno comments: UvrD-like helicase ATP-binding
up seq anno comments: UvrD-like helicase C-terminal
up seq anno feature ids: PRO_0000102055

83332:Rv0695
gene id: 83332:Rv0695
uniprot id: P9WP59
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Mycofactocin precursor peptide peptidase
up seq anno feature ids: PRO_0000415279

83332:Rv0345
gene id: 83332:Rv0345
uniprot id: O06296
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MobA-like NTP transferase

83332:Rv1526c
gene id: 83332:Rv1526c
uniprot id: P9WLV1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1526c
up seq anno feature ids: PRO_0000103872

83332:Rv2052c
gene id: 83332:Rv2052c
uniprot id: O53494
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Amidohydrolase 3
up seq anno comments: Disordered

83332:Rv0157
gene id: 83332:Rv0157
uniprot id: P96834
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NADP transhydrogenase beta-like

83332:Rv3276c
gene id: 83332:Rv3276c
uniprot id: P9WHL9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ATP-grasp
up seq anno comments: Disordered
up seq anno comments: N5-carboxyaminoimidazole ribonucleotide synthase
up seq anno feature ids: PRO_0000075000

83332:Rv1350
gene id: 83332:Rv1350
uniprot id: P9WGR9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv1350
up seq anno feature ids: PRO_0000054858

83332:Rv1015c
gene id: 83332:Rv1015c
uniprot id: P9WHB5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Acidic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL25
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000181570

83332:Rv2197c
gene id: 83332:Rv2197c
uniprot id: P9WLI9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2197c
up seq anno feature ids: PRO_0000103971

83332:Rv2024c
gene id: 83332:Rv2024c
uniprot id: O53470
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helicase ATP-binding

83332:Rv2851c
gene id: 83332:Rv2851c
uniprot id: P9WFQ5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase
up seq anno comments: UPF0039 protein Rv2851c
up seq anno feature ids: PRO_0000201921

83332:Rv2505c
gene id: 83332:Rv2505c
uniprot id: I6Y0X0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv3236c
gene id: 83332:Rv3236c
uniprot id: L7N665
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Cation/H+ exchanger
up seq anno comments: Helical

83332:Rv0925c
gene id: 83332:Rv0925c
uniprot id: I6Y946
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NADPH-dependent FMN reductase-like

83332:Rv2313c
gene id: 83332:Rv2313c
uniprot id: P9WLB7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2313c
up seq anno feature ids: PRO_0000104024

83332:Rv2680
gene id: 83332:Rv2680
uniprot id: O86317
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0391
gene id: 83332:Rv0391
uniprot id: P9WGB5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: O-succinylhomoserine sulfhydrylase
up seq anno feature ids: PRO_0000416406

83332:Rv2145c
gene id: 83332:Rv2145c
uniprot id: P9WMU1
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Cell wall synthesis protein Wag31
up seq anno comments: Disordered
up seq anno comments: Increases homooligomerization.
up seq anno comments: No interaction with PbpB (PBP3, FtsI). Slower growth, increased sensitivity to H(2)O(2) and to antibiotics ofloxacin and isoniazid, increased degradation of PbpB. Decreased survival in human macrophage line THP-1.
up seq anno comments: Phosphothreonine
up seq anno comments: Strong decrease in phosphorylation of Wag31.
up seq anno feature ids: PRO_0000064492

83332:Rv1159A
gene id: 83332:Rv1159A
uniprot id: P9WI93
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylalanine
up seq anno comments: Putative pterin-4-alpha-carbinolamine dehydratase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000063085

83332:Rv1049
gene id: 83332:Rv1049
uniprot id: I6Y5H3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH marR-type

83332:Rv1536
gene id: 83332:Rv1536
uniprot id: P9WFV3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Isoleucine--tRNA ligase
up seq anno feature ids: PRO_0000098550

83332:Rv0008c
gene id: 83332:Rv0008c
uniprot id: P9WJF3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Cell wall synthesis protein CwsA
up seq anno comments: Helical
up seq anno feature ids: PRO_0000103640

83332:Rv0873
gene id: 83332:Rv0873
uniprot id: P9WQF7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Probable acyl-CoA dehydrogenase FadE10
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000201209

83332:Rv3070
gene id: 83332:Rv3070
uniprot id: P9WP61
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Fluoride-specific ion channel FluC 2
up seq anno comments: Helical
up seq anno feature ids: PRO_0000110138

83332:Rv1201c
gene id: 83332:Rv1201c
uniprot id: P9WP21
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
up seq anno comments: Acyl-anhydride intermediate
up seq anno comments: Loss of activity.
up seq anno feature ids: PRO_0000412254

83332:Rv1360
gene id: 83332:Rv1360
uniprot id: P9WM03
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1360
up seq anno feature ids: PRO_0000014099

83332:Rv2545
gene id: 83332:Rv2545
uniprot id: P9WJ47
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB18
up seq anno feature ids: PRO_0000408064

83332:Rv1540
gene id: 83332:Rv1540
uniprot id: P9WHQ3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: S4 RNA-binding
up seq anno comments: Uncharacterized RNA pseudouridine synthase Rv1540
up seq anno feature ids: PRO_0000162743

83332:Rv0684
gene id: 83332:Rv0684
uniprot id: P9WNM7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Elongation factor G
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: tr-type G
up seq anno feature ids: PRO_0000091165

83332:Rv2374c
gene id: 83332:Rv2374c
uniprot id: P9WMK3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Heat-inducible transcription repressor HrcA
up seq anno feature ids: PRO_0000182512

83332:Rv1508c
gene id: 83332:Rv1508c
uniprot id: P71787
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv3198c
gene id: 83332:Rv3198c
uniprot id: P9WMP9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: ATP-dependent DNA helicase UvrD2
up seq anno comments: Disordered
up seq anno comments: HRDC
up seq anno comments: Loss of growth, no ATPase activity. No DNA unwinding. Does not translocate along DNA.
up seq anno comments: Not essential for growth, no helicase activity. Wild-type ATPase activity, translocates along DNA. No DNA unwinding.
up seq anno comments: Not required for growth
up seq anno comments: UvrD-like helicase ATP-binding
up seq anno comments: UvrD-like helicase C-terminal
up seq anno feature ids: PRO_0000102079

83332:Rv1846c
gene id: 83332:Rv1846c
uniprot id: P9WMJ5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cleavage
up seq anno comments: H-T-H motif
up seq anno comments: Important for dimerization
up seq anno comments: Transcriptional regulator BlaI
up seq anno feature ids: PRO_0000371419

83332:Rv3016
gene id: 83332:Rv3016
uniprot id: I6Y2A3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PknH-like extracellular
up seq anno feature ids: PRO_5039286958

83332:Rv0013
gene id: 83332:Rv0013
uniprot id: P9WN35
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Anthranilate synthase component 2
up seq anno comments: For GATase activity
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: Nucleophile; for GATase activity
up seq anno feature ids: PRO_0000390894

83332:Rv2169c
gene id: 83332:Rv2169c
uniprot id: O53503
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3348
gene id: 83332:Rv3348
uniprot id: P96234
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS110-like N-terminal

83332:Rv3882c
gene id: 83332:Rv3882c
uniprot id: P9WJE9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-1 secretion system protein EccE1
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393869

83332:Rv3165c
gene id: 83332:Rv3165c
uniprot id: O53315
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3712
gene id: 83332:Rv3712
uniprot id: I6Y4C7
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
up seq anno comments: Mur ligase central

83332:Rv1815
gene id: 83332:Rv1815
uniprot id: P9WLR9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1815
up seq anno feature ids: PRO_0000014109

83332:Rv0567
gene id: 83332:Rv0567
uniprot id: O53764
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Acetylserotonin O-methyltransferase dimerisation
up seq anno comments: O-methyltransferase
up seq anno comments: Proton acceptor

83332:Rv0533c
gene id: 83332:Rv0533c
uniprot id: P9WNG3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ACP-binding
up seq anno comments: Abolishes phosphorylation. Does not affect activity.
up seq anno comments: Loss of activity.
up seq anno comments: Mimics constitutive phosphorylation. Exhibits markedly decreased transacylation, malonyl-AcpM decarboxylation and condensing activities.
up seq anno comments: Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphothreonine
up seq anno comments: Removed
up seq anno comments: Retains 21% of wild-type activity. Loss of activity; when associated with A-161.
up seq anno comments: Retains 69% of wild-type activity. Loss of activity; when associated with A-42 or A-46.
up seq anno comments: Retains 7% of wild-type activity. Loss of activity; when associated with A-161.
up seq anno feature ids: PRO_0000110443

83332:Rv1067c
gene id: 83332:Rv1067c
uniprot id: Q79FT3
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0705
gene id: 83332:Rv0705
uniprot id: P9WH45
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein uS19
up seq anno feature ids: PRO_0000129856

83332:Rv0359
gene id: 83332:Rv0359
uniprot id: L0T550
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative zinc metalloprotease Rip2
up seq anno feature ids: PRO_0000422678

83332:Rv1212c
gene id: 83332:Rv1212c
uniprot id: P9WMZ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Alpha-maltose-1-phosphate synthase
up seq anno feature ids: PRO_0000413978

83332:Rv2064
gene id: 83332:Rv2064
uniprot id: Q10675
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nitrite/Sulfite reductase ferredoxin-like

83332:Rv0173
gene id: 83332:Rv0173
uniprot id: O07417
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mce/MlaD

83332:Rv3831
gene id: 83332:Rv3831
uniprot id: P96247
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3286c
gene id: 83332:Rv3286c
uniprot id: P9WGI3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: H-T-H motif
up seq anno comments: Interaction with polymerase core subunit RpoC
up seq anno comments: RNA polymerase sigma factor SigF
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-3
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000422954

83332:Rv0538
gene id: 83332:Rv0538
uniprot id: O06404
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Pro residues

83332:Rv2207
gene id: 83332:Rv2207
uniprot id: P9WP85
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000167056

83332:Rv2864c
gene id: 83332:Rv2864c
uniprot id: O33346
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: NTF2-like N-terminal transpeptidase
up seq anno comments: Penicillin-binding protein transpeptidase
up seq anno feature ids: PRO_5038431921

83332:Rv3397c
gene id: 83332:Rv3397c
uniprot id: P9WHP3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Phytoene synthase
up seq anno feature ids: PRO_0000067431

83332:Rv2515c
gene id: 83332:Rv2515c
uniprot id: I6XEH5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH cro/C1-type

83332:Rv3359
gene id: 83332:Rv3359
uniprot id: O50388
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NADH:flavin oxidoreductase/NADH oxidase N-terminal

83332:Rv1158c
gene id: 83332:Rv1158c
uniprot id: O06556
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010284889

83332:Rv2326c
gene id: 83332:Rv2326c
uniprot id: P9WQI7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transporter 1
up seq anno comments: ABC transporter 2
up seq anno comments: Helical
up seq anno comments: Uncharacterized ABC transporter ATP-binding protein Rv2326c
up seq anno feature ids: PRO_0000093266

83332:Rv0939
gene id: 83332:Rv0939
uniprot id: O86346
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Metallo-beta-lactamase

83332:Rv3175
gene id: 83332:Rv3175
uniprot id: O53325
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amidase

83332:Rv2155c
gene id: 83332:Rv2155c
uniprot id: P9WJL5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: UDP-N-acetylmuramoylalanine--D-glutamate ligase
up seq anno feature ids: PRO_0000109046

83332:Rv1638A
gene id: 83332:Rv1638A
uniprot id: L7N673
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0049
gene id: 83332:Rv0049
uniprot id: P9WM85
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0049
up seq anno feature ids: PRO_0000103658

83332:Rv1322A
gene id: 83332:Rv1322A
uniprot id: L7N6B1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: VOC

83332:Rv2976c
gene id: 83332:Rv2976c
uniprot id: P9WFQ9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Proton acceptor
up seq anno comments: Uracil-DNA glycosylase
up seq anno feature ids: PRO_0000176119

83332:Rv1062
gene id: 83332:Rv1062
uniprot id: O53410
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: DGA/G
up seq anno comments: GXGXXG
up seq anno comments: GXSXG
up seq anno comments: Nucleophile
up seq anno comments: PNPLA
up seq anno comments: Proton acceptor

83332:Rv1916
gene id: 83332:Rv1916
uniprot id: O07717
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative isocitrate lyase subunit B
up seq anno feature ids: PRO_0000432567

83332:Rv0548c
gene id: 83332:Rv0548c
uniprot id: P9WNP5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1,4-dihydroxy-2-naphthoyl-CoA synthase
up seq anno comments: Important for catalysis
up seq anno comments: Loss of DHNA-CoA synthase activity.
up seq anno comments: Nearly abolishes DHNA-CoA synthase activity.
up seq anno comments: Reduces affinity for substrate. Nearly abolishes DHNA-CoA synthase activity.
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000399471

83332:Rv0884c
gene id: 83332:Rv0884c
uniprot id: P9WQ73
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetylalanine
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Phosphoserine aminotransferase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000150188

83332:Rv0019c
gene id: 83332:Rv0019c
uniprot id: P9WJB5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Does not affect phosphorylation.
up seq anno comments: FHA
up seq anno comments: FHA domain-containing protein FhaB
up seq anno comments: Helical
up seq anno comments: Impairs interaction with PknB and PapA5.
up seq anno comments: Impairs interaction with PknB. Does not affect interaction with PapA5.
up seq anno comments: Lack of phosphorylation.
up seq anno comments: Phosphothreonine; by PknB
up seq anno feature ids: PRO_0000419671

83332:Rv1721c
gene id: 83332:Rv1721c
uniprot id: P9WJ53
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Putative antitoxin VapB12
up seq anno feature ids: PRO_0000408059

83332:Rv1552
gene id: 83332:Rv1552
uniprot id: P9WN91
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Fumarate reductase flavoprotein subunit
up seq anno comments: Tele-8alpha-FAD histidine
up seq anno feature ids: PRO_0000158664

83332:Rv2391
gene id: 83332:Rv2391
uniprot id: P9WJ03
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3'-(S-cysteinyl)-tyrosine (Tyr-Cys)
up seq anno comments: Disordered
up seq anno comments: Strong decrease in activity.
up seq anno comments: Sulfite reductase [ferredoxin]
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000199952

83332:Rv2034
gene id: 83332:Rv2034
uniprot id: O53478
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Does not bind DNA and does not form dimers.
up seq anno comments: Does not bind DNA, but retains the capacity to form dimers; when associated with G-32.
up seq anno comments: Does not bind DNA, but retains the capacity to form dimers; when associated with G-35.
up seq anno comments: H-T-H motif
up seq anno comments: HTH arsR-type
up seq anno comments: HTH-type transcriptional regulator Rv2034
up seq anno feature ids: PRO_0000419177

83332:Rv3209
gene id: 83332:Rv3209
uniprot id: O05857
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1856c
gene id: 83332:Rv1856c
uniprot id: P9WGQ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative oxidoreductase Rv1856c
up seq anno feature ids: PRO_0000415509

83332:Rv2211c
gene id: 83332:Rv2211c
uniprot id: P9WN51
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Aminomethyltransferase
up seq anno feature ids: PRO_0000122574

83332:Rv3030
gene id: 83332:Rv3030
uniprot id: P9WJZ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Probable S-adenosylmethionine-dependent methyltransferase Rv3030
up seq anno feature ids: PRO_0000413014

83332:Rv2179c
gene id: 83332:Rv2179c
uniprot id: P9WJ73
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3'-5' exoribonuclease Rv2179c
up seq anno comments: RNA binding
up seq anno comments: Strongly reduces enzyme activity.
up seq anno feature ids: PRO_0000424958

83332:Rv1670
gene id: 83332:Rv1670
uniprot id: O53917
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF427

83332:Rv3894c
gene id: 83332:Rv3894c
uniprot id: O05450
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: FtsK
up seq anno comments: Helical

83332:Rv3722c
gene id: 83332:Rv3722c
uniprot id: O69689
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Aspartate aminotransferase
up seq anno feature ids: PRO_0000450667

83332:Rv0577
gene id: 83332:Rv0577
uniprot id: P9WIR3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Glyoxalase 1
up seq anno comments: Glyoxalase 2
up seq anno comments: Putative glyoxylase CFP32
up seq anno comments: VOC 1
up seq anno comments: VOC 2
up seq anno feature ids: PRO_0000089565

83332:Rv1074c
gene id: 83332:Rv1074c
uniprot id: O53422
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Proton acceptor
up seq anno comments: Thiolase C-terminal
up seq anno comments: Thiolase N-terminal

83332:Rv0715
gene id: 83332:Rv0715
uniprot id: P9WHB7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL24
up seq anno feature ids: PRO_0000130684

83332:Rv1256c
gene id: 83332:Rv1256c
uniprot id: P9WPN5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cytochrome P450 130
up seq anno comments: The binding mode of azoles and some arylamines are reverted from type II to type I because of hydrophobic and steric interactions with the alanine side chain.
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052285

83332:Rv0894
gene id: 83332:Rv0894
uniprot id: P9WKP9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0894
up seq anno feature ids: PRO_0000103735

83332:Rv1223
gene id: 83332:Rv1223
uniprot id: O06291
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Charge relay system
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: PDZ
up seq anno comments: Periplasmic
up seq anno comments: Polar residues
up seq anno comments: Probable serine protease HtrA1
up seq anno feature ids: PRO_0000450814

83332:Rv2074
gene id: 83332:Rv2074
uniprot id: P9WLL7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 17.8-fold decrease in catalytic efficiency.
up seq anno comments: 2.6-fold decrease in catalytic efficiency.
up seq anno comments: 2.7-fold decrease in catalytic efficiency.
up seq anno comments: 3.3-fold decrease in catalytic efficiency.
up seq anno comments: 4.7-fold decrease in catalytic efficiency.
up seq anno comments: 44.5-fold decrease in catalytic efficiency.
up seq anno comments: 8.9-fold decrease in catalytic efficiency.
up seq anno comments: F420H(2)-dependent biliverdin reductase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000103945

83332:Rv3841
gene id: 83332:Rv3841
uniprot id: P9WNE5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Turn
up seq anno comments: Bacterioferritin BfrB
up seq anno comments: Ferritin-like diiron
up seq anno comments: No large change in protein assembly or structure, decreased thermostability, 3.5-fold reduction in oxidation of Fe(2+), 20% reduction in Fe(3+) release rate.
up seq anno comments: Protein no longer targeted to encapsulin nanocompartments.
up seq anno comments: Removed
up seq anno comments: Targeting peptide
up seq anno feature ids: PRO_0000392942

83332:Rv1038c
gene id: 83332:Rv1038c
uniprot id: P9WNJ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxJ
up seq anno feature ids: PRO_0000167802

83332:Rv1877
gene id: 83332:Rv1877
uniprot id: P9WG85
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter Rv1877
up seq anno feature ids: PRO_0000390887

83332:Rv2732c
gene id: 83332:Rv2732c
uniprot id: O33237
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0843
gene id: 83332:Rv0843
uniprot id: I6XWE5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Dehydrogenase E1 component
up seq anno comments: Disordered

83332:Rv1690
gene id: 83332:Rv1690
uniprot id: O33192
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Increases KdpD induction at 0 and 250 uMK(+).
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LprJ
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000434609

83332:Rv2874
gene id: 83332:Rv2874
uniprot id: P9WG63
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Helical
up seq anno comments: Protein DipZ
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_0000079911

83332:Rv3408
gene id: 83332:Rv3408
uniprot id: P9WF49
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC47
up seq anno feature ids: PRO_0000104129

83332:Rv0665
gene id: 83332:Rv0665
uniprot id: P9WFB1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC8
up seq anno feature ids: PRO_0000407871

83332:Rv1513
gene id: 83332:Rv1513
uniprot id: P71792
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase FkbM

83332:Rv3040c
gene id: 83332:Rv3040c
uniprot id: O53287
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nudix hydrolase

83332:Rv1170
gene id: 83332:Rv1170
uniprot id: P9WJN3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase
up seq anno feature ids: PRO_0000399826

83332:Rv1787
gene id: 83332:Rv1787
uniprot id: P9WI13
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE25
up seq anno feature ids: PRO_0000379588

83332:Rv0063
gene id: 83332:Rv0063
uniprot id: O53608
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv1826
gene id: 83332:Rv1826
uniprot id: P9WN55
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Glycine cleavage system H protein
up seq anno comments: Lipoyl-binding
up seq anno comments: N-acetylserine
up seq anno comments: N6-lipoyllysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000166228

83332:Rv2986c
gene id: 83332:Rv2986c
uniprot id: P9WMK7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Propeptide
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Propeptide
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Bacterial histone-like domain
up seq anno comments: Basic residues
up seq anno comments: DNA-binding protein HupB
up seq anno comments: DNA-binding protein HupB, propeptide removed
up seq anno comments: Degenerate repeats region
up seq anno comments: Disordered
up seq anno comments: N-acetylmethionine
up seq anno comments: N6,N6,N6-trimethyllysine
up seq anno comments: N6-acetyllysine
up seq anno comments: No change in trimethylation by human SUV39H1.
up seq anno comments: Removed
up seq anno comments: Removed; alternate
up seq anno comments: Significantly decreased trimethylation of HupB by host SUV39H1, increased bacterial survival in human macrophages, SUV39H1 no longer inhibits biofilm formation.
up seq anno feature ids: PRO_0000104950
up seq anno feature ids: PRO_0000455388
up seq anno feature ids: PRO_0000455389

83332:Rv3536c
gene id: 83332:Rv3536c
uniprot id: I6XHH5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Fumarylacetoacetase-like C-terminal

83332:Rv0236c
gene id: 83332:Rv0236c
uniprot id: P96419
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Alpha-(1->3)-arabinofuranosyltransferase
up seq anno comments: F5/8 type C
up seq anno comments: Helical
up seq anno feature ids: PRO_0000420582

83332:Rv0726c
gene id: 83332:Rv0726c
uniprot id: P9WFI7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0726c
up seq anno feature ids: PRO_0000361242

83332:Rv2822c
gene id: 83332:Rv2822c
uniprot id: P9WJG1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: CRISPR system Cms protein Csm2
up seq anno feature ids: PRO_0000418225

83332:Rv0067c
gene id: 83332:Rv0067c
uniprot id: O53612
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3685c
gene id: 83332:Rv3685c
uniprot id: P9WPM5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 137
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052296

83332:Rv3310
gene id: 83332:Rv3310
uniprot id: O53361
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Phosphatidylinositol-3-phosphatase
up seq anno feature ids: PRO_5008778597

83332:Rv0559c
gene id: 83332:Rv0559c
uniprot id: P9WKL3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv0559c
up seq anno feature ids: PRO_0000419778

83332:Rv3077
gene id: 83332:Rv3077
uniprot id: Q6MX15
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Sulfatase N-terminal

83332:Rv0029
gene id: 83332:Rv0029
uniprot id: P71599
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF5631
up seq anno comments: DUF5632

83332:Rv1731
gene id: 83332:Rv1731
uniprot id: P9WNX7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2
up seq anno feature ids: PRO_0000310711

83332:Rv3500c
gene id: 83332:Rv3500c
uniprot id: I6Y3P5
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1195
gene id: 83332:Rv1195
uniprot id: Q79FR3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE family protein PE13
up seq anno feature ids: PRO_5007710417

83332:Rv2217
gene id: 83332:Rv2217
uniprot id: P9WK83
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: BPL/LPL catalytic
up seq anno comments: Loss of activity.
up seq anno comments: Lowers pKa of active site Cys
up seq anno comments: Octanoyltransferase
up seq anno feature ids: PRO_0000062851

83332:Rv0878c
gene id: 83332:Rv0878c
uniprot id: P9WI35
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 4 X 10 AA approximate repeats
up seq anno comments: Helical
up seq anno comments: Uncharacterized PPE family protein PPE13
up seq anno feature ids: PRO_0000217844

83332:Rv0855
gene id: 83332:Rv0855
uniprot id: I6Y8Y0
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2403c
gene id: 83332:Rv2403c
uniprot id: P71740
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PknH-like extracellular
up seq anno feature ids: PRO_5039595067

83332:Rv2685
gene id: 83332:Rv2685
uniprot id: P9WPD7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized transporter Rv2685
up seq anno feature ids: PRO_0000172515

83332:Rv2044c
gene id: 83332:Rv2044c
uniprot id: O53487
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2887
gene id: 83332:Rv2887
uniprot id: P9WME9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes binding to Rv0560c promoter.
up seq anno comments: Attenuates the ability to bind salicylate.
up seq anno comments: HTH marR-type
up seq anno comments: HTH-type transcriptional repressor Rv2887
up seq anno feature ids: PRO_0000054410

83332:Rv3221c
gene id: 83332:Rv3221c
uniprot id: P9WPQ1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Biotinyl-binding
up seq anno comments: Biotinylated protein TB7.3
up seq anno comments: N6-biotinyllysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000146838

83332:Rv0676c
gene id: 83332:Rv0676c
uniprot id: P9WJV1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Siderophore exporter MmpL5
up seq anno feature ids: PRO_0000103568

83332:Rv1867
gene id: 83332:Rv1867
uniprot id: P95148
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thiolase-like protein type 1 additional C-terminal

83332:Rv2221c
gene id: 83332:Rv2221c
uniprot id: P9WN27
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Adenylyl removase
up seq anno comments: Adenylyl transferase
up seq anno comments: Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme
up seq anno feature ids: PRO_0000209257

83332:Rv2714
gene id: 83332:Rv2714
uniprot id: I6YA29
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3904c
gene id: 83332:Rv3904c
uniprot id: P9WNH9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxE
up seq anno feature ids: PRO_0000167819

83332:Rv2521
gene id: 83332:Rv2521
uniprot id: P9WIE1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Putative peroxiredoxin Rv2521
up seq anno comments: Redox-active
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_0000396096

83332:Rv3733c
gene id: 83332:Rv3733c
uniprot id: O69700
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nudix hydrolase

83332:Rv1616
gene id: 83332:Rv1616
uniprot id: O06133
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0588
gene id: 83332:Rv0588
uniprot id: O07790
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2832c
gene id: 83332:Rv2832c
uniprot id: I6X5H3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv0077c
gene id: 83332:Rv0077c
uniprot id: O53622
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv1266c
gene id: 83332:Rv1266c
uniprot id: P9WI71
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Abolished autophosphorylation.
up seq anno comments: Abolished kinase activity.
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Phosphothreonine
up seq anno comments: Pro residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknH
up seq anno feature ids: PRO_0000171218

83332:Rv0904c
gene id: 83332:Rv0904c
uniprot id: P9WQH9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CoA carboxyltransferase C-terminal
up seq anno comments: CoA carboxyltransferase N-terminal
up seq anno comments: Probable biotin-dependent acyl-coenzyme A carboxylase beta3 subunit
up seq anno feature ids: PRO_0000199773

83332:Rv3851
gene id: 83332:Rv3851
uniprot id: P96226
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1923
gene id: 83332:Rv1923
uniprot id: P95290
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Beta-lactamase-related

83332:Rv1565c
gene id: 83332:Rv1565c
uniprot id: O06625
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Acyltransferase 3
up seq anno comments: Helical
up seq anno comments: SGNH

83332:Rv1887
gene id: 83332:Rv1887
uniprot id: O07745
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv2743c
gene id: 83332:Rv2743c
uniprot id: I6YA50
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative envelope-preserving system protein Rv2743c
up seq anno feature ids: PRO_0000450868

83332:Rv1380
gene id: 83332:Rv1380
uniprot id: P9WIT7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Aspartate carbamoyltransferase
up seq anno feature ids: PRO_0000113163

83332:Rv1700
gene id: 83332:Rv1700
uniprot id: I6X235
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2.1-fold decrease in KM for ADPR. 1940-fold decrease in kcat with ADPR as substrate.
up seq anno comments: 2.3-fold decrease in KM for ADPR. 1150-fold decrease in kcat with ADPR as substrate.
up seq anno comments: 2.7-fold decrease in KM for ADPR. 300-fold decrease in kcat with ADPR as substrate.
up seq anno comments: 3-fold decrease in KM for ADPR. 910-fold decrease in kcat with ADPR as substrate.
up seq anno comments: ADP-ribose pyrophosphatase
up seq anno comments: Nudix box
up seq anno comments: Nudix hydrolase
up seq anno comments: Proton acceptor
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000449350

83332:Rv1217c
gene id: 83332:Rv1217c
uniprot id: O05318
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Multidrug efflux system permease protein Rv1217c
up seq anno feature ids: PRO_0000447331

83332:Rv3418c
gene id: 83332:Rv3418c
uniprot id: P9WPE5
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Co-chaperonin GroES
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylalanine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000174788

83332:Rv0342
gene id: 83332:Rv0342
uniprot id: P9WJ99
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Isoniazid-induced protein IniA
up seq anno feature ids: PRO_0000390791

83332:Rv1523
gene id: 83332:Rv1523
uniprot id: Q50584
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase type 11

83332:Rv1181
gene id: 83332:Rv1181
uniprot id: A0A089QRB9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Lipid Binding
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Acyl-ester intermediate; for acyltransferase activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase activity
up seq anno comments: Acyltransferase (AT)
up seq anno comments: Beta-ketoacyl reductase (KR)
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase (DH)
up seq anno comments: Enoylreductase (ER)
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Linker domain (LD)
up seq anno comments: Mycolipanoate synthase
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Pseudo beta-ketoacyl reductase (PsiKR)
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000438278

83332:Rv3820c
gene id: 83332:Rv3820c
uniprot id: P9WIK7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Loss of sulfolipid-1 (SL-1) production.
up seq anno comments: Trehalose-2-sulfate acyltransferase PapA2
up seq anno feature ids: PRO_0000314662

83332:Rv1806
gene id: 83332:Rv1806
uniprot id: L7N656
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv0600c
gene id: 83332:Rv0600c
uniprot id: O07778
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Histidine kinase; second part
up seq anno comments: Sensor histidine kinase component HK1
up seq anno feature ids: PRO_0000391079

83332:Rv1836c
gene id: 83332:Rv1836c
uniprot id: P9WLQ9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1836c
up seq anno feature ids: PRO_0000103910

83332:Rv2998
gene id: 83332:Rv2998
uniprot id: O53245
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0247c
gene id: 83332:Rv0247c
uniprot id: O53669
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type

83332:Rv0737
gene id: 83332:Rv0737
uniprot id: I6Y8K3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH marR-type

83332:Rv3871
gene id: 83332:Rv3871
uniprot id: P9WNB1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cells unable to export EsxB.
up seq anno comments: ESX-1 secretion system protein EccCb1
up seq anno comments: FtsK 1
up seq anno comments: FtsK 2
up seq anno feature ids: PRO_0000393429

83332:Rv2502c
gene id: 83332:Rv2502c
uniprot id: I6YDK7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase beta1 subunit
up seq anno comments: CoA carboxyltransferase C-terminal
up seq anno comments: CoA carboxyltransferase N-terminal
up seq anno feature ids: PRO_0000452368

83332:Rv3695
gene id: 83332:Rv3695
uniprot id: O69663
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: RDD

83332:Rv3320c
gene id: 83332:Rv3320c
uniprot id: P9WF53
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC44
up seq anno feature ids: PRO_0000407896

83332:Rv0569
gene id: 83332:Rv0569
uniprot id: P9WM83
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0569
up seq anno feature ids: PRO_0000392682

83332:Rv3135
gene id: 83332:Rv3135
uniprot id: Q6MX07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE50
up seq anno feature ids: PRO_0000378484

83332:Rv3516
gene id: 83332:Rv3516
uniprot id: O53561
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: About 50% succinylation in vitro, reduces specific activity 7-fold.
up seq anno comments: Enoyl-CoA hydratase EchA19
up seq anno comments: N6-succinyllysine
up seq anno comments: Nearly wild-type levels of succinylation in vitro, reduces specific activity 8-fold.
up seq anno comments: Very low levels of succinylation in vitro, reduces specific activity 15-fold.
up seq anno feature ids: PRO_0000456533

83332:Rv1406
gene id: 83332:Rv1406
uniprot id: P9WND3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Methionyl-tRNA formyltransferase
up seq anno feature ids: PRO_0000083000

83332:Rv1364c
gene id: 83332:Rv1364c
uniprot id: P9WLZ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes autophosphorylation.
up seq anno comments: Anti-sigma factor kinase region
up seq anno comments: Decreases ATPase activity. Abolishes autophosphorylation. Can still be phosphorylated by PknD.
up seq anno comments: Does not affect ATPase activity. Abolishes autophosphorylation.
up seq anno comments: Does not affect autophosphorylation. 10-fold decrease in phosphatase activity.
up seq anno comments: Leads to the accumulation of the autophosphorylated protein. 10-fold decrease in phosphatase activity.
up seq anno comments: Multidomain regulatory protein Rv1364c
up seq anno comments: PAC
up seq anno comments: PPM-type phosphatase
up seq anno comments: Phosphoserine; by PknD
up seq anno comments: Phosphoserine; by autocatalysis
up seq anno comments: Phosphothreonine; by PknD
up seq anno comments: STAS
up seq anno comments: Strong decrease in ATPase activity. Abolishes autophosphorylation.
up seq anno feature ids: PRO_0000103833

83332:Rv0374c
gene id: 83332:Rv0374c
uniprot id: O53709
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type

83332:Rv0978c
gene id: 83332:Rv0978c
uniprot id: Q79FU2
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Repeat
up seq anno comments: NHL 1
up seq anno comments: NHL 2
up seq anno comments: NHL 3
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS17
up seq anno feature ids: PRO_5007710445

83332:Rv0865
gene id: 83332:Rv0865
uniprot id: I6Y8Y8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MoaB/Mog

83332:Rv1237
gene id: 83332:Rv1237
uniprot id: P9WG01
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Trehalose transport system permease protein SugB
up seq anno feature ids: PRO_0000419316

83332:Rv0197
gene id: 83332:Rv0197
uniprot id: L0T2Z1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 4Fe-4S Mo/W bis-MGD-type

83332:Rv2414c
gene id: 83332:Rv2414c
uniprot id: P71729
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ComEC/Rec2-related protein
up seq anno comments: Helical

83332:Rv0687
gene id: 83332:Rv0687
uniprot id: P9WGS7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized NAD-dependent oxidoreductase Rv0687
up seq anno feature ids: PRO_0000416411

83332:Rv2231c
gene id: 83332:Rv2231c
uniprot id: P9WQ89
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Uncharacterized aminotransferase Rv2231c
up seq anno feature ids: PRO_0000123927

83332:Rv3642c
gene id: 83332:Rv3642c
uniprot id: I6Y464
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Antitoxin VbhA

83332:Rv2724c
gene id: 83332:Rv2724c
uniprot id: O33229
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv1966
gene id: 83332:Rv1966
uniprot id: L7N698
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv1347c
gene id: 83332:Rv1347c
uniprot id: P9WK15
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Lysine N-acyltransferase MbtK
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000103819

83332:Rv2532c
gene id: 83332:Rv2532c
uniprot id: P95021
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3009c
gene id: 83332:Rv3009c
uniprot id: P9WN61
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
up seq anno feature ids: PRO_0000148814

83332:Rv0260c
gene id: 83332:Rv0260c
uniprot id: P95217
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: OmpR/PhoB-type

83332:Rv3389c
gene id: 83332:Rv3389c
uniprot id: I6YBZ8
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-hydroxyacyl-thioester dehydratase Y
up seq anno comments: Disordered
up seq anno comments: MaoC-like
up seq anno feature ids: PRO_0000448720

83332:Rv2358
gene id: 83332:Rv2358
uniprot id: P9WMI5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH arsR-type
up seq anno comments: HTH-type transcriptional repressor SmtB
up seq anno feature ids: PRO_0000419166

83332:Rv3195
gene id: 83332:Rv3195
uniprot id: O53341
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2842c
gene id: 83332:Rv2842c
uniprot id: P9WH17
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Ribosome maturation factor RimP
up seq anno feature ids: PRO_0000181892

83332:Rv0087
gene id: 83332:Rv0087
uniprot id: Q10884
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: NADH-quinone oxidoreductase subunit D
up seq anno comments: NADH:ubiquinone oxidoreductase 30kDa subunit

83332:Rv1276c
gene id: 83332:Rv1276c
uniprot id: P9WGF9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1276c
up seq anno feature ids: PRO_0000214573

83332:Rv3013
gene id: 83332:Rv3013
uniprot id: O53260
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ACT

83332:Rv1741
gene id: 83332:Rv1741
uniprot id: P9WF71
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative ribonuclease VapC34
up seq anno feature ids: PRO_0000413609

83332:Rv1450c
gene id: 83332:Rv1450c
uniprot id: Q79FP2
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0386
gene id: 83332:Rv0386
uniprot id: O53720
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Guanylate cyclase
up seq anno comments: HTH luxR-type

83332:Rv1933c
gene id: 83332:Rv1933c
uniprot id: P95281
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal

83332:Rv2754c
gene id: 83332:Rv2754c
uniprot id: P9WG57
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Flavin-dependent thymidylate synthase
up seq anno comments: Involved in ionization of N3 of dUMP, leading to its activation
up seq anno comments: Loss of catalytic activity since it is not able to complement an E.coli thyA deletion mutant.
up seq anno comments: Still able to complement an E.coli thyA deletion mutant.
up seq anno comments: ThyX
up seq anno comments: ThyX motif
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000175570

83332:Rv2992c
gene id: 83332:Rv2992c
uniprot id: P9WFV9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Glutamate--tRNA ligase
up seq anno feature ids: PRO_0000119610

83332:Rv2424c
gene id: 83332:Rv2424c
uniprot id: P71924
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS116/IS110/IS902 C-terminal

83332:Rv0207c
gene id: 83332:Rv0207c
uniprot id: P96389
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NYN

83332:Rv2242
gene id: 83332:Rv2242
uniprot id: P9WPH5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2242
up seq anno feature ids: PRO_0000165949

83332:Rv1712
gene id: 83332:Rv1712
uniprot id: P9WPA9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno comments: Cytidylate kinase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000131943

83332:Rv1227c
gene id: 83332:Rv1227c
uniprot id: O33223
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF304
up seq anno comments: Helical

83332:Rv3432c
gene id: 83332:Rv3432c
uniprot id: I6YG46
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine

83332:Rv0356c
gene id: 83332:Rv0356c
uniprot id: O06307
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Thioesterase

83332:Rv1191
gene id: 83332:Rv1191
uniprot id: O05293
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv1012
gene id: 83332:Rv1012
uniprot id: O05597
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv2194
gene id: 83332:Rv2194
uniprot id: P9WP35
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Cytochrome bc1 complex cytochrome c subunit
up seq anno comments: Cytochrome c 1
up seq anno comments: Cytochrome c 2
up seq anno comments: Helical
up seq anno comments: axial binding residue
up seq anno comments: covalent
up seq anno feature ids: PRO_0000108450

83332:Rv2370c
gene id: 83332:Rv2370c
uniprot id: O05828
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CdaR GGDEF-like
up seq anno comments: Disordered
up seq anno comments: PucR C-terminal helix-turn-helix

83332:Rv1848
gene id: 83332:Rv1848
uniprot id: P9WFE7
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno comments: Urease subunit gamma
up seq anno feature ids: PRO_0000098019

83332:Rv3559c
gene id: 83332:Rv3559c
uniprot id: I6YCF0
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA reductase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000452309

83332:Rv2021c
gene id: 83332:Rv2021c
uniprot id: O53467
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: Putative antitoxin HigA2
up seq anno feature ids: PRO_0000432911

83332:Rv2512c
gene id: 83332:Rv2512c
uniprot id: P60230
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Transposase for insertion sequence element IS1081
up seq anno feature ids: PRO_0000211350

83332:Rv3375
gene id: 83332:Rv3375
uniprot id: P9WQ93
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Charge relay system
up seq anno comments: Putative amidase AmiD
up seq anno feature ids: PRO_0000105260

83332:Rv3214
gene id: 83332:Rv3214
uniprot id: Q6MWZ7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Acid phosphatase
up seq anno comments: Proton donor/acceptor
up seq anno comments: Tele-phosphohistidine intermediate
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000437244

83332:Rv0064A
gene id: 83332:Rv0064A
uniprot id: P0CW29
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB1
up seq anno feature ids: PRO_0000408051

83332:Rv1416
gene id: 83332:Rv1416
uniprot id: P9WHE9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: 6,7-dimethyl-8-ribityllumazine synthase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000134772

83332:Rv0046c
gene id: 83332:Rv0046c
uniprot id: P9WKI1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Inositol-3-phosphate synthase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000195203

83332:Rv0909
gene id: 83332:Rv0909
uniprot id: P9WJ07
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin Rv0909
up seq anno feature ids: PRO_0000406886

83332:Rv3162c
gene id: 83332:Rv3162c
uniprot id: O53312
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0876c
gene id: 83332:Rv0876c
uniprot id: P9WKR5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0876c
up seq anno feature ids: PRO_0000103719

83332:Rv1248c
gene id: 83332:Rv1248c
uniprot id: P9WIS5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Region
up seq anno comments: 2-oxoglutarate dehydrogenase E1, C-terminal part
up seq anno comments: 2-oxoglutarate dehydrogenase E1, N-terminal part
up seq anno comments: Disordered
up seq anno comments: Linker
up seq anno comments: Multifunctional 2-oxoglutarate metabolism enzyme
up seq anno comments: Proton acceptor; for succinyltransferase activity
up seq anno comments: Succinyltransferase E2
up seq anno feature ids: PRO_0000310722

83332:Rv1059
gene id: 83332:Rv1059
uniprot id: O53407
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 2,4-diaminopentanoate dehydrogenase C-terminal
up seq anno comments: Dihydrodipicolinate reductase N-terminal

83332:Rv0697
gene id: 83332:Rv0697
uniprot id: I6Y8H4
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Glucose-methanol-choline oxidoreductase C-terminal
up seq anno comments: Glucose-methanol-choline oxidoreductase N-terminal

83332:Rv1533
gene id: 83332:Rv1533
uniprot id: O06179
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative monooxygenase Rv1533
up seq anno feature ids: PRO_0000393572

83332:Rv2123
gene id: 83332:Rv2123
uniprot id: Q79FH3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE37
up seq anno feature ids: PRO_0000379114

83332:Rv1357c
gene id: 83332:Rv1357c
uniprot id: P9WM07
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: EAL
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1357c
up seq anno feature ids: PRO_0000103828

83332:Rv3582c
gene id: 83332:Rv3582c
uniprot id: P9WKG9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
up seq anno comments: Positions MEP for the nucleophilic attack
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000075592

83332:Rv3056
gene id: 83332:Rv3056
uniprot id: P9WNT1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: DNA polymerase IV 2
up seq anno comments: Substrate discrimination
up seq anno comments: UmuC
up seq anno feature ids: PRO_0000173926

83332:Rv2542
gene id: 83332:Rv2542
uniprot id: P95011
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2204c
gene id: 83332:Rv2204c
uniprot id: P9WMN5
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: Protein Rv2204c
up seq anno comments: Removed
up seq anno feature ids: PRO_0000077019

83332:Rv0271c
gene id: 83332:Rv0271c
uniprot id: P95228
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv3400
gene id: 83332:Rv3400
uniprot id: P9WKZ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3400
up seq anno feature ids: PRO_0000104119

83332:Rv2031c
gene id: 83332:Rv2031c
uniprot id: P9WMK1
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno comments: Alpha-crystallin
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Removed
up seq anno comments: sHSP
up seq anno feature ids: PRO_0000126011

83332:Rv2854
gene id: 83332:Rv2854
uniprot id: O05805
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Serine aminopeptidase S33

83332:Rv0098
gene id: 83332:Rv0098
uniprot id: P9WM67
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: (2E)-enoyl-[ACP] glycyltransferase
up seq anno comments: Decrease in acyl-CoA thioesterase activity.
up seq anno comments: Loss of acyl-CoA thioesterase activity.
up seq anno feature ids: PRO_0000103668

83332:Rv3306c
gene id: 83332:Rv3306c
uniprot id: L7N690
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Peptidase M20 dimerisation

83332:Rv3705c
gene id: 83332:Rv3705c
uniprot id: I6XI06
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PknH-like extracellular
up seq anno feature ids: PRO_5039438952

83332:Rv0936
gene id: 83332:Rv0936
uniprot id: P9WG09
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Phosphate transport system permease protein PstA 2
up seq anno feature ids: PRO_0000060203

83332:Rv1508A
gene id: 83332:Rv1508A
uniprot id: Q79FN0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: NAD(P)-binding

83332:Rv0398c
gene id: 83332:Rv0398c
uniprot id: P95206
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5038849690

83332:Rv3526
gene id: 83332:Rv3526
uniprot id: P71875
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-ketosteroid-9-alpha-monooxygenase, oxygenase component
up seq anno comments: Rieske
up seq anno feature ids: PRO_0000404098

83332:Rv0757
gene id: 83332:Rv0757
uniprot id: P71814
up seq anno parent labels: Binding Site
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: 4-aspartylphosphate
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Response regulatory

83332:Rv3329
gene id: 83332:Rv3329
uniprot id: O53379
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable aminotransferase Rv3329
up seq anno feature ids: PRO_0000432513

83332:Rv1587c
gene id: 83332:Rv1587c
uniprot id: O06603
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: HNH nuclease

83332:Rv2436
gene id: 83332:Rv2436
uniprot id: P71913
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Carbohydrate kinase PfkB
up seq anno comments: Proton acceptor

83332:Rv3109
gene id: 83332:Rv3109
uniprot id: P9WJS3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: GTP 3',8-cyclase 1
up seq anno comments: Radical SAM core
up seq anno feature ids: PRO_0000152976

83332:Rv0218
gene id: 83332:Rv0218
uniprot id: P96400
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Oxidoreductase molybdopterin-binding

83332:Rv2252
gene id: 83332:Rv2252
uniprot id: P9WP29
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: DAGKc
up seq anno comments: Diacylglycerol kinase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000386484

83332:Rv0366c
gene id: 83332:Rv0366c
uniprot id: O53701
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Zeta toxin

83332:Rv1028A
gene id: 83332:Rv1028A
uniprot id: Q79FT7
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0881
gene id: 83332:Rv0881
uniprot id: P9WFY3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized tRNA/rRNA methyltransferase Rv0881
up seq anno feature ids: PRO_0000159838

83332:Rv2060
gene id: 83332:Rv2060
uniprot id: O86339
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2552c
gene id: 83332:Rv2552c
uniprot id: I6Y120
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SDH C-terminal
up seq anno comments: Shikimate dehydrogenase substrate binding N-terminal

83332:Rv2913c
gene id: 83332:Rv2913c
uniprot id: P9WJH9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2913c
up seq anno feature ids: PRO_0000182708

83332:Rv1022
gene id: 83332:Rv1022
uniprot id: P96378
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5039135574

83332:Rv2729c
gene id: 83332:Rv2729c
uniprot id: O33234
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1858
gene id: 83332:Rv1858
uniprot id: P9WG13
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Molybdenum transport system permease protein ModB
up seq anno feature ids: PRO_0000060116

83332:Rv2381c
gene id: 83332:Rv2381c
uniprot id: P71719
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier

83332:Rv3570c
gene id: 83332:Rv3570c
uniprot id: P9WJA1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Flavin-dependent monooxygenase, oxygenase subunit HsaA
up seq anno feature ids: PRO_0000404501

83332:Rv2523c
gene id: 83332:Rv2523c
uniprot id: P9WQD3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Holo-[acyl-carrier-protein] synthase
up seq anno feature ids: PRO_0000175675

83332:Rv1286
gene id: 83332:Rv1286
uniprot id: P9WNM5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adenylyl-sulfate kinase
up seq anno comments: Bifunctional enzyme CysN/CysC
up seq anno comments: Disordered
up seq anno comments: G1
up seq anno comments: G2
up seq anno comments: G3
up seq anno comments: G4
up seq anno comments: G5
up seq anno comments: Phosphoserine intermediate
up seq anno comments: Sulfate adenylyltransferase
up seq anno comments: tr-type G
up seq anno feature ids: PRO_0000091537

83332:Rv0105c
gene id: 83332:Rv0105c
uniprot id: P9WHB1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein bL28A
up seq anno feature ids: PRO_0000178512

83332:Rv0959A
gene id: 83332:Rv0959A
uniprot id: P9WJ55
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB9
up seq anno feature ids: PRO_0000408058

83332:Rv1955
gene id: 83332:Rv1955
uniprot id: P9WJA5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Probable endoribonuclease HigB1
up seq anno feature ids: PRO_0000407370

83332:Rv1426c
gene id: 83332:Rv1426c
uniprot id: O06832
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0058
gene id: 83332:Rv0058
uniprot id: P9WMR3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno comments: DOD-type homing endonuclease
up seq anno comments: Disordered
up seq anno comments: Endonuclease PI-MtuHIP
up seq anno comments: Replicative DNA helicase, 1st part
up seq anno comments: Replicative DNA helicase, 2nd part
up seq anno comments: SF4 helicase; first part
up seq anno comments: SF4 helicase; second part
up seq anno feature ids: PRO_0000013282
up seq anno feature ids: PRO_0000013283
up seq anno feature ids: PRO_0000013284

83332:Rv0921
gene id: 83332:Rv0921
uniprot id: I6WZS4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Resolvase/invertase-type recombinase catalytic

83332:Rv0887c
gene id: 83332:Rv0887c
uniprot id: P9WKQ3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Uncharacterized protein Rv0887c
up seq anno comments: VOC
up seq anno feature ids: PRO_0000103729

83332:Rv1258c
gene id: 83332:Rv1258c
uniprot id: P9WJX9
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Multidrug efflux pump Tap
up seq anno comments: Shows higher efflux activity. Causes clinically relevant high-level drug resistance to pyrazinamide (PZA), isoniazid (INH) and streptomycin (SM).
up seq anno comments: Shows higher efflux activity. Causes clinically relevant low-level drug resistance to pyrazinamide (PZA), isoniazid (INH) and streptomycin (SM).
up seq anno feature ids: PRO_0000103772

83332:Rv0707
gene id: 83332:Rv0707
uniprot id: P9WH37
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: KH type-2
up seq anno comments: Small ribosomal subunit protein uS3
up seq anno feature ids: PRO_0000130158

83332:Rv1110
gene id: 83332:Rv1110
uniprot id: P9WKG1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000128841

83332:Rv0712
gene id: 83332:Rv0712
uniprot id: I6Y8I5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Abolished formylglycine-generating enzyme activity.
up seq anno comments: Formylglycine-generating enzyme
up seq anno comments: Strongly reduced formylglycine-generating enzyme activity.
up seq anno feature ids: PRO_0000444619

83332:Rv3442c
gene id: 83332:Rv3442c
uniprot id: P9WH25
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Small ribosomal subunit protein uS9
up seq anno feature ids: PRO_0000111379

83332:Rv1543
gene id: 83332:Rv1543
uniprot id: P9WGS1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv1543
up seq anno feature ids: PRO_0000054856

83332:Rv1903
gene id: 83332:Rv1903
uniprot id: O07729
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1371
gene id: 83332:Rv1371
uniprot id: P71799
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Cytochrome b5 heme-binding
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2214c
gene id: 83332:Rv2214c
uniprot id: P9WGS3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1
up seq anno comments: Probable oxidoreductase EphD
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000054854

83332:Rv3067
gene id: 83332:Rv3067
uniprot id: I6YB21
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv3067
up seq anno feature ids: PRO_0000432520

83332:Rv0287
gene id: 83332:Rv0287
uniprot id: O53692
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ESAT-6-like protein EsxG
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000434997

83332:Rv3410c
gene id: 83332:Rv3410c
uniprot id: P9WKI5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized oxidoreductase Rv3410c
up seq anno feature ids: PRO_0000093782

83332:Rv0110
gene id: 83332:Rv0110
uniprot id: O53632
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Peptidase S54 rhomboid

83332:Rv3752c
gene id: 83332:Rv3752c
uniprot id: O69719
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: CMP/dCMP-type deaminase
up seq anno comments: Proton donor

83332:Rv3382c
gene id: 83332:Rv3382c
uniprot id: P9WKF9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000128842

83332:Rv1982A
gene id: 83332:Rv1982A
uniprot id: P9WJ29
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB36
up seq anno feature ids: PRO_0000408078

83332:Rv3715c
gene id: 83332:Rv3715c
uniprot id: P9WHI3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Zinc Finger
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Zinc Finger
up seq anno comments: C4-type
up seq anno comments: Recombination protein RecR
up seq anno comments: Toprim
up seq anno feature ids: PRO_0000190350

83332:Rv0946c
gene id: 83332:Rv0946c
uniprot id: P9WN69
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decrease in activity.
up seq anno comments: Disordered
up seq anno comments: Glucose-6-phosphate isomerase
up seq anno comments: Loss of activity.
up seq anno comments: N-acetylthreonine
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno feature ids: PRO_0000180677

83332:Rv2701c
gene id: 83332:Rv2701c
uniprot id: P9WKI9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Inositol-1-monophosphatase SuhB
up seq anno comments: Less than 4% of wild-type activity.
up seq anno comments: N-acetylthreonine
up seq anno comments: No effect on activity. 10-fold more resistant to inhibition by Li(+).
up seq anno comments: Removed
up seq anno feature ids: PRO_0000142564

83332:Rv3889c
gene id: 83332:Rv3889c
uniprot id: P9WJC9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESX-2 secretion-associated protein EspG2
up seq anno feature ids: PRO_0000394153

83332:Rv1651c
gene id: 83332:Rv1651c
uniprot id: Q79FL8
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: C-terminal domain
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS30
up seq anno comments: PGRS domain
up seq anno feature ids: PRO_5004287725

83332:Rv0408
gene id: 83332:Rv0408
uniprot id: P9WHP1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Phosphate acetyltransferase
up seq anno feature ids: PRO_0000179135

83332:Rv3540c
gene id: 83332:Rv3540c
uniprot id: I6Y3T7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase
up seq anno comments: Loss of activity.
up seq anno comments: No change in activity.
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000452243

83332:Rv2164c
gene id: 83332:Rv2164c
uniprot id: O06213
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Pro residues

83332:Rv0768
gene id: 83332:Rv0768
uniprot id: I6X9R9
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Aldehyde dehydrogenase

83332:Rv3341
gene id: 83332:Rv3341
uniprot id: P9WJY9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: AB hydrolase-1
up seq anno comments: Homoserine O-acetyltransferase
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000155731

83332:Rv0585c
gene id: 83332:Rv0585c
uniprot id: O53781
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3719
gene id: 83332:Rv3719
uniprot id: O69686
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv0228
gene id: 83332:Rv0228
uniprot id: P96410
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Acyltransferase 3
up seq anno comments: Helical

83332:Rv3144c
gene id: 83332:Rv3144c
uniprot id: I6X6H8
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: PPE
up seq anno comments: Polar residues

83332:Rv1071c
gene id: 83332:Rv1071c
uniprot id: O53419
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Enoyl-CoA hydratase/isomerase

83332:Rv3088
gene id: 83332:Rv3088
uniprot id: P9WKC3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Probable diacyglycerol O-acyltransferase Tgs4
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000222914

83332:Rv0891c
gene id: 83332:Rv0891c
uniprot id: P9WMV1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Guanylate cyclase
up seq anno comments: Uncharacterized protein Rv0891c
up seq anno feature ids: PRO_0000074130

83332:Rv1728c
gene id: 83332:Rv1728c
uniprot id: P71986
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2071c
gene id: 83332:Rv2071c
uniprot id: P9WGB1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Precorrin-4 C(11)-methyltransferase
up seq anno feature ids: PRO_0000150396

83332:Rv2564
gene id: 83332:Rv2564
uniprot id: P9WQI5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter
up seq anno comments: Uncharacterized ABC transporter ATP-binding protein Rv2564
up seq anno feature ids: PRO_0000093268

83332:Rv2923c
gene id: 83332:Rv2923c
uniprot id: P9WL19
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2923c
up seq anno feature ids: PRO_0000104104

83332:Rv1559
gene id: 83332:Rv1559
uniprot id: P9WG95
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ACT-like
up seq anno comments: L-threonine dehydratase biosynthetic IlvA
up seq anno comments: N-acetylserine
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000185577

83332:Rv1032c
gene id: 83332:Rv1032c
uniprot id: P96368
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Transmembrane
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Sensor histidine kinase TrcS
up seq anno feature ids: PRO_0000451062

83332:Rv2739c
gene id: 83332:Rv2739c
uniprot id: O33282
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Glycosyl transferase family 28 C-terminal

83332:Rv2568c
gene id: 83332:Rv2568c
uniprot id: P9WL95
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2568c
up seq anno feature ids: PRO_0000104045

83332:Rv3218
gene id: 83332:Rv3218
uniprot id: O05848
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DAGKc

83332:Rv0464c
gene id: 83332:Rv0464c
uniprot id: O53749
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carboxymuconolactone decarboxylase-like

83332:Rv2534c
gene id: 83332:Rv2534c
uniprot id: P9WNM3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Elongation factor P
up seq anno feature ids: PRO_0000094292

83332:Rv1296
gene id: 83332:Rv1296
uniprot id: P9WKE7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Homoserine kinase
up seq anno feature ids: PRO_0000156590

83332:Rv3037c
gene id: 83332:Rv3037c
uniprot id: P9WJZ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized S-adenosylmethionine-dependent methyltransferase Rv3037c
up seq anno feature ids: PRO_0000413013

83332:Rv0165c
gene id: 83332:Rv0165c
uniprot id: Q79G00
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HTH gntR-type

83332:Rv1965
gene id: 83332:Rv1965
uniprot id: O53966
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0070c
gene id: 83332:Rv0070c
uniprot id: P9WGI7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Site
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Plays an important role in substrate specificity
up seq anno comments: Serine hydroxymethyltransferase 2
up seq anno feature ids: PRO_0000113619

83332:Rv3730c
gene id: 83332:Rv3730c
uniprot id: O69697
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3183
gene id: 83332:Rv3183
uniprot id: O53333
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: Putative antitoxin HigA3
up seq anno feature ids: PRO_0000432912

83332:Rv1214c
gene id: 83332:Rv1214c
uniprot id: L7N6A7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PE
up seq anno feature ids: PRO_5010314126

83332:Rv1592c
gene id: 83332:Rv1592c
uniprot id: P9WK89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable inactive lipase Rv1592c
up seq anno feature ids: PRO_0000392687

83332:Rv0723
gene id: 83332:Rv0723
uniprot id: P9WHD7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein uL15
up seq anno feature ids: PRO_0000104755

83332:Rv0376c
gene id: 83332:Rv0376c
uniprot id: O53711
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: XdhC Rossmann
up seq anno comments: XdhC- CoxI

83332:Rv2081c
gene id: 83332:Rv2081c
uniprot id: P9WLK5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2081c
up seq anno feature ids: PRO_0000103952

83332:Rv1555
gene id: 83332:Rv1555
uniprot id: P9WNB5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Fumarate reductase subunit D
up seq anno comments: Helical
up seq anno feature ids: PRO_0000196547

83332:Rv0555
gene id: 83332:Rv0555
uniprot id: P9WK11
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
up seq anno feature ids: PRO_0000341784

83332:Rv1913
gene id: 83332:Rv1913
uniprot id: O07720
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv1382
gene id: 83332:Rv1382
uniprot id: P71810
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2224c
gene id: 83332:Rv2224c
uniprot id: P9WHR3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: AB hydrolase-1
up seq anno comments: Cannot cleave GroEL2.
up seq anno comments: Cannot complement the growth defect of the disruption mutant. Cannot cleave GroEL2. Is unable to hydrolyze azocasein.
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: Serine protease Hip1
up seq anno comments: Small decrease in activity with azocasein as substrate. Almost abolishes cleavage of GroEL2.
up seq anno feature ids: PRO_0000027329

83332:Rv3078
gene id: 83332:Rv3078
uniprot id: I6Y2H3
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0016c
gene id: 83332:Rv0016c
uniprot id: P9WKD1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Can rescue the deletion mutant.
up seq anno comments: Cannot rescue the deletion mutant.
up seq anno comments: Cytoplasmic
up seq anno comments: Helical; Signal-anchor for type II membrane protein
up seq anno comments: Peptidoglycan D,D-transpeptidase PbpA
up seq anno comments: Periplasmic
up seq anno comments: Transpeptidase
up seq anno feature ids: PRO_0000343832

83332:Rv2051c
gene id: 83332:Rv2051c
uniprot id: O53493
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Apolipoprotein N-acyltransferase
up seq anno comments: Basic and acidic residues
up seq anno comments: Bifunctional apolipoprotein N-acyltransferase/polyprenol monophosphomannose synthase
up seq anno comments: CN hydrolase
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Nucleophile
up seq anno comments: Polyprenol monophosphomannose synthase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000434582

83332:Rv2884
gene id: 83332:Rv2884
uniprot id: I6X5M3
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: OmpR/PhoB-type

83332:Rv3762c
gene id: 83332:Rv3762c
uniprot id: O69728
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv3726
gene id: 83332:Rv3726
uniprot id: O69693
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alcohol dehydrogenase-like C-terminal
up seq anno comments: Alcohol dehydrogenase-like N-terminal

83332:Rv0958
gene id: 83332:Rv0958
uniprot id: P71552
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Sigma-54 factor interaction

83332:Rv2711
gene id: 83332:Rv2711
uniprot id: P9WMH1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: HTH dtxR-type
up seq anno comments: Iron-dependent repressor IdeR
up seq anno feature ids: PRO_0000201108

83332:Rv3901c
gene id: 83332:Rv3901c
uniprot id: O05444
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0418
gene id: 83332:Rv0418
uniprot id: P96264
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Lipid Binding
up seq anno labels: Mass
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: Expressed in M.bovis, lipidated.
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: PA
up seq anno comments: Probable lipoprotein aminopeptidase LpqL
up seq anno comments: Proton acceptor
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000434901

83332:Rv3550
gene id: 83332:Rv3550
uniprot id: I6Y3U6
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA hydrolase
up seq anno feature ids: PRO_0000452310

83332:Rv0778
gene id: 83332:Rv0778
uniprot id: P9WPN9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 126
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052282

83332:Rv2176
gene id: 83332:Rv2176
uniprot id: P9WI63
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Decrease in autophosphorylation activity. Does not affect transphosphorylation activity.
up seq anno comments: Disordered
up seq anno comments: Does not affect autophosphorylation and transphosphorylation activities.
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Lack of kinase activity.
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknL
up seq anno comments: Strong decrease in autophosphorylation activity. Lack of transphosphorylation activity.
up seq anno feature ids: PRO_0000171226

83332:Rv0239
gene id: 83332:Rv0239
uniprot id: P9WJ41
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB24
up seq anno feature ids: PRO_0000408069

83332:Rv0255c
gene id: 83332:Rv0255c
uniprot id: P9WP95
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Cobyric acid synthase
up seq anno comments: GATase cobBQ-type
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000141312

83332:Rv1082
gene id: 83332:Rv1082
uniprot id: P9WJN1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Mycothiol S-conjugate amidase
up seq anno feature ids: PRO_0000423187

83332:Rv3099c
gene id: 83332:Rv3099c
uniprot id: O05777
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: MDMPI C-terminal
up seq anno comments: Mycothiol-dependent maleylpyruvate isomerase metal-binding

83332:Rv0901
gene id: 83332:Rv0901
uniprot id: P9WJG5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein ArfC
up seq anno feature ids: PRO_0000103741

83332:Rv1738
gene id: 83332:Rv1738
uniprot id: P9WLS3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Uncharacterized protein Rv1738
up seq anno feature ids: PRO_0000103896

83332:Rv1398c
gene id: 83332:Rv1398c
uniprot id: P9WLZ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative antitoxin VapB10
up seq anno feature ids: PRO_0000103837

83332:Rv3848
gene id: 83332:Rv3848
uniprot id: P96229
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2933
gene id: 83332:Rv2933
uniprot id: P96202
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyltransferase
up seq anno comments: Beta-ketoacyl reductase
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase
up seq anno comments: Enoylreductase
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: For malonyltransferase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Lack of dehydration reaction.
up seq anno comments: Lack of phosphopantetheinylation.
up seq anno comments: N-acetylthreonine
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Phenolphthiocerol/phthiocerol polyketide synthase subunit C
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Removed
up seq anno feature ids: PRO_0000406948

83332:Rv3228
gene id: 83332:Rv3228
uniprot id: O05873
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: CP-type G
up seq anno comments: Disordered
up seq anno comments: EngC GTPase

83332:Rv0477
gene id: 83332:Rv0477
uniprot id: P9WKV9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0477
up seq anno feature ids: PRO_0000014074

83332:Rv1874
gene id: 83332:Rv1874
uniprot id: O07755
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: EthD

83332:Rv0279c
gene id: 83332:Rv0279c
uniprot id: L0T4W6
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS4
up seq anno feature ids: PRO_0000458021

83332:Rv1687c
gene id: 83332:Rv1687c
uniprot id: O33189
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv3912
gene id: 83332:Rv3912
uniprot id: P9WJ65
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Anti-sigma-M factor RsmA
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno feature ids: PRO_0000422684

83332:Rv2871
gene id: 83332:Rv2871
uniprot id: P9WL41
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Antitoxin VapB43
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000104085

83332:Rv0080
gene id: 83332:Rv0080
uniprot id: P9WMA5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0080
up seq anno feature ids: PRO_0000392680

83332:Rv3742c
gene id: 83332:Rv3742c
uniprot id: O69709
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3197
gene id: 83332:Rv3197
uniprot id: O53343
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC1 atypical kinase-like

83332:Rv0597c
gene id: 83332:Rv0597c
uniprot id: I6WYU2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA
up seq anno comments: DUF4143

83332:Rv1386
gene id: 83332:Rv1386
uniprot id: P9WIH1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE family immunomodulator PE15
up seq anno feature ids: PRO_0000023572

83332:Rv2632c
gene id: 83332:Rv2632c
uniprot id: P9WL61
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Uncharacterized protein Rv2632c
up seq anno feature ids: PRO_0000104072

83332:Rv0422c
gene id: 83332:Rv0422c
uniprot id: P9WG77
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000192023

83332:Rv1603
gene id: 83332:Rv1603
uniprot id: P9WMM5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Phosphoribosyl isomerase A
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000142085

83332:Rv0733
gene id: 83332:Rv0733
uniprot id: P9WKF5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Adenylate kinase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: LID
up seq anno comments: NMP
up seq anno feature ids: PRO_0000158806

83332:Rv1273c
gene id: 83332:Rv1273c
uniprot id: P9WQJ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Helical
up seq anno comments: Uncharacterized ABC transporter ATP-binding protein Rv1273c
up seq anno feature ids: PRO_0000093264

83332:Rv0390
gene id: 83332:Rv0390
uniprot id: P95198
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rhodanese

83332:Rv2092c
gene id: 83332:Rv2092c
uniprot id: P9WMR1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: DEVH box
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno comments: Probable helicase HelY
up seq anno feature ids: PRO_0000102102

83332:Rv3858c
gene id: 83332:Rv3858c
uniprot id: P9WN19
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: 4Fe-4S ferredoxin-type
up seq anno comments: Glutamate synthase [NADPH] small chain
up seq anno feature ids: PRO_0000419546

83332:Rv1102c
gene id: 83332:Rv1102c
uniprot id: P9WIH9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Endoribonuclease MazF3
up seq anno feature ids: PRO_0000406306

83332:Rv0566c
gene id: 83332:Rv0566c
uniprot id: P9WFK9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: UPF0234 protein Rv0566c
up seq anno feature ids: PRO_0000106188

83332:Rv2270
gene id: 83332:Rv2270
uniprot id: P9WK73
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Prevents bacterial uptake by a human macrophage-like cell line
up seq anno comments: Putative lipoprotein LppN
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018113

83332:Rv1925
gene id: 83332:Rv1925
uniprot id: I6Y7V6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv1061
gene id: 83332:Rv1061
uniprot id: O53409
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Glutamine amidotransferase type-2

83332:Rv2235
gene id: 83332:Rv2235
uniprot id: P9WGA7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized SURF1-like protein Rv2235
up seq anno feature ids: PRO_0000215662

83332:Rv0026
gene id: 83332:Rv0026
uniprot id: P9WMB1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized protein Rv0026
up seq anno feature ids: PRO_0000103643

83332:Rv2578c
gene id: 83332:Rv2578c
uniprot id: P9WL79
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Radical SAM core
up seq anno comments: Uncharacterized protein Rv2578c
up seq anno feature ids: PRO_0000104061

83332:Rv2895c
gene id: 83332:Rv2895c
uniprot id: P9WL31
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding FR-type
up seq anno comments: Uncharacterized protein Rv2895c
up seq anno feature ids: PRO_0000104093

83332:Rv3772
gene id: 83332:Rv3772
uniprot id: P9WML5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Putative phenylalanine aminotransferase
up seq anno feature ids: PRO_0000153517

83332:Rv0683
gene id: 83332:Rv0683
uniprot id: P9WH29
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Small ribosomal subunit protein uS7
up seq anno feature ids: PRO_0000124306

83332:Rv3246c
gene id: 83332:Rv3246c
uniprot id: P9WGM7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-aspartylphosphate
up seq anno comments: DNA-binding response regulator MtrA
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: No phosphorylation by EnvZ kinase in vitro, does not bind DNA. Poor growth in infected macrophages and upon mouse infection. Fewer bacteria are mistargeted to lysosomes.
up seq anno comments: No phosphorylation by EnvZ kinase in vitro. Binds DNA in the absence but not presence of EnvZ and ATP. A merodiploid strain has late growth defects. May mimic the phosphorylated state.
up seq anno comments: No phosphorylation by EnvZ kinase in vitro. Binds fbpB and oriCDNA in the presence and absence of EnvZ and ATP. A merodiploid strain has late growth defects, fbpB is down-regulated. May be constitutively active.
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Phosphorylated by EnvZ kinase in vitro, reverses many phenotypes of mtrB knockout.
up seq anno comments: Response regulatory
up seq anno feature ids: PRO_0000081143

83332:Rv2721c
gene id: 83332:Rv2721c
uniprot id: I6XF52
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno feature ids: PRO_5039426421

83332:Rv3208
gene id: 83332:Rv3208
uniprot id: O05858
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv0790c
gene id: 83332:Rv0790c
uniprot id: I6XWA9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transglutaminase-like

83332:Rv1917c
gene id: 83332:Rv1917c
uniprot id: Q79FI9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: PPE family protein PPE34
up seq anno feature ids: PRO_0000437939

83332:Rv0296c
gene id: 83332:Rv0296c
uniprot id: Q6MX51
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Sulfatase N-terminal

83332:Rv0254c
gene id: 83332:Rv0254c
uniprot id: O53676
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno comments: GMP-histidine intermediate

83332:Rv1613
gene id: 83332:Rv1613
uniprot id: P9WFY1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Proton acceptor
up seq anno comments: Tryptophan synthase alpha chain
up seq anno feature ids: PRO_0000098811

83332:Rv1098c
gene id: 83332:Rv1098c
uniprot id: P9WN93
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Absence of fumarase activity.
up seq anno comments: Fumarate hydratase class II
up seq anno comments: Important for catalytic activity
up seq anno comments: N-acetylalanine
up seq anno comments: Proton donor/acceptor
up seq anno comments: Removed
up seq anno comments: in site B
up seq anno feature ids: PRO_0000161289

83332:Rv2839c
gene id: 83332:Rv2839c
uniprot id: P9WKK1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: G1
up seq anno comments: G2
up seq anno comments: G3
up seq anno comments: G4
up seq anno comments: G5
up seq anno comments: Pro residues
up seq anno comments: Translation initiation factor IF-2
up seq anno comments: tr-type G
up seq anno feature ids: PRO_0000137224

83332:Rv0084
gene id: 83332:Rv0084
uniprot id: Q10881
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0911
gene id: 83332:Rv0911
uniprot id: I6XA34
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: VOC

83332:Rv3198A
gene id: 83332:Rv3198A
uniprot id: P9WN17
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Glutaredoxin
up seq anno comments: Putative glutaredoxin Rv3198.1
up seq anno feature ids: PRO_0000363861

83332:Rv1748
gene id: 83332:Rv1748
uniprot id: P72005
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2421c
gene id: 83332:Rv2421c
uniprot id: P9WJJ5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable nicotinate-nucleotide adenylyltransferase
up seq anno feature ids: PRO_0000181427

83332:Rv2922A
gene id: 83332:Rv2922A
uniprot id: P9WQC9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Acylphosphatase
up seq anno comments: Acylphosphatase-like
up seq anno feature ids: PRO_0000158556

83332:Rv3783
gene id: 83332:Rv3783
uniprot id: P72049
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC-2 type transporter transmembrane
up seq anno comments: Helical

83332:Rv0487
gene id: 83332:Rv0487
uniprot id: P9WKU9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0487
up seq anno feature ids: PRO_0000103689

83332:Rv1884c
gene id: 83332:Rv1884c
uniprot id: O07747
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Loss of resuscitating activity on M.luteus.
up seq anno comments: Resuscitation-promoting factor RpfC
up seq anno feature ids: PRO_0000421029

83332:Rv2239c
gene id: 83332:Rv2239c
uniprot id: P9WLG9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2239c
up seq anno feature ids: PRO_0000103987

83332:Rv3427c
gene id: 83332:Rv3427c
uniprot id: Q50701
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative ATP-binding protein Rv3427c in insertion sequence
up seq anno feature ids: PRO_0000075481

83332:Rv3058c
gene id: 83332:Rv3058c
uniprot id: P95100
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1697
gene id: 83332:Rv1697
uniprot id: O33198
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: SteA-like C-terminal

83332:Rv3923c
gene id: 83332:Rv3923c
uniprot id: P9WGZ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Ribonuclease P protein component
up seq anno feature ids: PRO_0000198494

83332:Rv3754
gene id: 83332:Rv3754
uniprot id: O69721
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Prephenate dehydrogenase
up seq anno comments: Prephenate/arogenate dehydrogenase
up seq anno feature ids: PRO_0000432509

83332:Rv0608
gene id: 83332:Rv0608
uniprot id: P9WJ39
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB28
up seq anno feature ids: PRO_0000408072

83332:Rv1801
gene id: 83332:Rv1801
uniprot id: P9WI09
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE29
up seq anno feature ids: PRO_0000378481

83332:Rv1471
gene id: 83332:Rv1471
uniprot id: L7N664
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Region
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno comments: Redox-active
up seq anno comments: Thioredoxin

83332:Rv2643
gene id: 83332:Rv2643
uniprot id: I6X4W4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Phosphotyrosine protein phosphatase I

83332:Rv0432
gene id: 83332:Rv0432
uniprot id: P9WGE9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Polar residues
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: Superoxide dismutase [Cu-Zn]
up seq anno feature ids: PRO_0000032840

83332:Rv1283c
gene id: 83332:Rv1283c
uniprot id: P9WFZ7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Putative peptide transport permease protein Rv1283c
up seq anno feature ids: PRO_0000060291

83332:Rv0748
gene id: 83332:Rv0748
uniprot id: O53811
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB31
up seq anno feature ids: PRO_0000408075

83332:Rv0923c
gene id: 83332:Rv0923c
uniprot id: I6XWK6
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno comments: Proton acceptor

83332:Rv2104c
gene id: 83332:Rv2104c
uniprot id: P9WJ27
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB37
up seq anno feature ids: PRO_0000408079

83332:Rv3868
gene id: 83332:Rv3868
uniprot id: P9WPH9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decrease in substrate-binding and in catalytic efficiency.
up seq anno comments: Does not affect substrate-binding, but decreases the catalytic efficiency and the Vmax.
up seq anno comments: Does not distord the binding site architecture. No change in catalytic efficiency and Vmax.
up seq anno comments: ESX-1 secretion system protein EccA1
up seq anno comments: Large increase in the Km and strong decrease in catalytic efficiency. Loses the ability to self-associate in the presence of ATP and the cooperativity is nearly abolished.
up seq anno feature ids: PRO_0000063049

83332:Rv1115
gene id: 83332:Rv1115
uniprot id: O06567
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0576
gene id: 83332:Rv0576
uniprot id: O53773
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH arsR-type

83332:Rv1935c
gene id: 83332:Rv1935c
uniprot id: P95279
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative enoyl-CoA hydratase EchA13
up seq anno feature ids: PRO_0000438539

83332:Rv1403c
gene id: 83332:Rv1403c
uniprot id: P9WLY9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1403c
up seq anno feature ids: PRO_0000014101

83332:Rv2589
gene id: 83332:Rv2589
uniprot id: P9WQ79
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: 4-aminobutyrate aminotransferase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000120386

83332:Rv1720c
gene id: 83332:Rv1720c
uniprot id: P9WFA3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribonuclease VapC12
up seq anno feature ids: PRO_0000407873

83332:Rv2905
gene id: 83332:Rv2905
uniprot id: P9WK67
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppW
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018118

83332:Rv3439c
gene id: 83332:Rv3439c
uniprot id: I6YC49
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Acidic residues
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv0694
gene id: 83332:Rv0694
uniprot id: P9WND7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: FMN hydroxy acid dehydrogenase
up seq anno comments: Pre-mycofactocin synthase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000390892

83332:Rv2411c
gene id: 83332:Rv2411c
uniprot id: P9WLA9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized protein Rv2411c
up seq anno feature ids: PRO_0000104032

83332:Rv2731
gene id: 83332:Rv2731
uniprot id: I6XF60
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Pro residues

83332:Rv1366
gene id: 83332:Rv1366
uniprot id: P9WLZ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1366
up seq anno feature ids: PRO_0000103834

83332:Rv0126
gene id: 83332:Rv0126
uniprot id: P9WQ19
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno comments: Trehalose synthase/amylase TreS
up seq anno feature ids: PRO_0000412906

83332:Rv2107
gene id: 83332:Rv2107
uniprot id: L7N6B5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv0090
gene id: 83332:Rv0090
uniprot id: P9WM71
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0090
up seq anno feature ids: PRO_0000103664

83332:Rv3567c
gene id: 83332:Rv3567c
uniprot id: P9WND9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Flavin-dependent monooxygenase, reductase subunit HsaB
up seq anno feature ids: PRO_0000404505

83332:Rv0379
gene id: 83332:Rv0379
uniprot id: Q6MX43
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Calcium dodecin
up seq anno feature ids: PRO_0000429121

83332:Rv0798c
gene id: 83332:Rv0798c
uniprot id: I6WZG6
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Sequence Conflict
up seq anno comments: Removed; alternate
up seq anno comments: Type 1 encapsulin shell protein
up seq anno comments: Type 1 encapsulin shell protein, N-terminally processed
up seq anno feature ids: PRO_0000455313
up seq anno feature ids: PRO_0000455314

83332:Rv0268c
gene id: 83332:Rv0268c
uniprot id: P95225
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Putative antitoxin Rv0268c
up seq anno feature ids: PRO_0000434894

83332:Rv0760c
gene id: 83332:Rv0760c
uniprot id: I6WZD7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nuclear transport factor 2

83332:Rv1111c
gene id: 83332:Rv1111c
uniprot id: O86351
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: DUF6542
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1624c
gene id: 83332:Rv1624c
uniprot id: O06141
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2850c
gene id: 83332:Rv2850c
uniprot id: P9WPR3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: N-acetylmethionine
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized protein Rv2850c
up seq anno comments: VWFA
up seq anno feature ids: PRO_0000206874

83332:Rv3385c
gene id: 83332:Rv3385c
uniprot id: P9WF13
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Antitoxin VapB46
up seq anno feature ids: PRO_0000408050

83332:Rv0094c
gene id: 83332:Rv0094c
uniprot id: Q50655
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: HNH nuclease

83332:Rv0587
gene id: 83332:Rv0587
uniprot id: I6Y870
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3293
gene id: 83332:Rv3293
uniprot id: L7N650
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Aldehyde dehydrogenase

83332:Rv1765c
gene id: 83332:Rv1765c
uniprot id: O06798
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HNH nuclease

83332:Rv3535c
gene id: 83332:Rv3535c
uniprot id: P9WQH3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2200-fold decrease in catalytic efficiency with coenzyme A.
up seq anno comments: 6600-fold decrease in catalytic efficiency with coenzyme A.
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Propanal dehydrogenase (CoA-propanoylating)
up seq anno feature ids: PRO_0000387688

83332:Rv2283
gene id: 83332:Rv2283
uniprot id: P9WLE9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2283
up seq anno feature ids: PRO_0000104004

83332:Rv1489A
gene id: 83332:Rv1489A
uniprot id: L7N6A8
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1594
gene id: 83332:Rv1594
uniprot id: P9WJK1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Quinolinate synthase
up seq anno feature ids: PRO_0000155791

83332:Rv2433c
gene id: 83332:Rv2433c
uniprot id: P71916
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3065
gene id: 83332:Rv3065
uniprot id: P9WGF1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Multidrug resistance protein Mmr
up seq anno feature ids: PRO_0000108120

83332:Rv0704
gene id: 83332:Rv0704
uniprot id: P9WHA5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Large ribosomal subunit protein uL2
up seq anno feature ids: PRO_0000129587

83332:Rv3794
gene id: 83332:Rv3794
uniprot id: P9WNL9
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Helical
up seq anno comments: Probable arabinosyltransferase A
up seq anno comments: Resistance to EMB.
up seq anno feature ids: PRO_0000220564

83332:Rv1896c
gene id: 83332:Rv1896c
uniprot id: P9WFH7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv1896c
up seq anno feature ids: PRO_0000361238

83332:Rv0498
gene id: 83332:Rv0498
uniprot id: P9WKU1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv0498
up seq anno feature ids: PRO_0000014076

83332:Rv2249c
gene id: 83332:Rv2249c
uniprot id: P9WN81
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glycerol-3-phosphate dehydrogenase 1
up seq anno feature ids: PRO_0000126100

83332:Rv2742c
gene id: 83332:Rv2742c
uniprot id: O33285
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Putative envelope-preserving system protein Rv2742c
up seq anno feature ids: PRO_0000450867

83332:Rv2549c
gene id: 83332:Rv2549c
uniprot id: P95004
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: 23S rRNA-specific endonuclease VapC20
up seq anno comments: Loss of 23S rRNA cleavage.
up seq anno comments: PINc
up seq anno feature ids: PRO_0000407879

83332:Rv3764c
gene id: 83332:Rv3764c
uniprot id: O69729
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Probable sensor histidine kinase TcrY
up seq anno feature ids: PRO_0000412200

83332:Rv0621
gene id: 83332:Rv0621
uniprot id: I6X9F4
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2378c
gene id: 83332:Rv2378c
uniprot id: P9WKF7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: L-lysine N6-monooxygenase MbtG
up seq anno feature ids: PRO_0000261312

83332:Rv3213c
gene id: 83332:Rv3213c
uniprot id: O05853
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA

83332:Rv1476
gene id: 83332:Rv1476
uniprot id: O53167
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0444c
gene id: 83332:Rv0444c
uniprot id: P9WGX5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Anti-sigma-K factor RskA
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000313835

83332:Rv1293
gene id: 83332:Rv1293
uniprot id: P9WIU7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Diaminopimelate decarboxylase
up seq anno comments: Interchain (with C-375)
up seq anno comments: Interchain (with C-72)
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000149929

83332:Rv3881c
gene id: 83332:Rv3881c
uniprot id: P9WJD9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: Cleavage; by MycP1
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion-associated protein EspB
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000096612

83332:Rv0062
gene id: 83332:Rv0062
uniprot id: Q79G13
up seq anno parent labels: Active Site
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Disulfide Bond
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor

83332:Rv1952
gene id: 83332:Rv1952
uniprot id: P95262
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB14
up seq anno feature ids: PRO_0000408061

83332:Rv2776c
gene id: 83332:Rv2776c
uniprot id: O86347
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: FAD-binding FR-type

83332:Rv3125c
gene id: 83332:Rv3125c
uniprot id: P9WHY5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE49
up seq anno feature ids: PRO_0000378483

83332:Rv1413
gene id: 83332:Rv1413
uniprot id: P9WLY5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1413
up seq anno feature ids: PRO_0000103839

83332:Rv1770
gene id: 83332:Rv1770
uniprot id: O06803
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Peptidase M28

83332:Rv2948c
gene id: 83332:Rv2948c
uniprot id: P9WQ61
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: Carrier
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: p-hydroxybenzoic acid--AMP ligase FadD22
up seq anno feature ids: PRO_0000406350

83332:Rv1730c
gene id: 83332:Rv1730c
uniprot id: P71988
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Beta-lactamase-related

83332:Rv2600
gene id: 83332:Rv2600
uniprot id: P9WFG5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0719 transmembrane protein Rv2600
up seq anno feature ids: PRO_0000104070

83332:Rv2916c
gene id: 83332:Rv2916c
uniprot id: P9WGD7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Signal recognition particle protein
up seq anno feature ids: PRO_0000101163

83332:Rv3449
gene id: 83332:Rv3449
uniprot id: I6YC58
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Charge relay system
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Mycosin-4
up seq anno comments: Peptidase S8
up seq anno feature ids: PRO_5007674266

83332:Rv3268
gene id: 83332:Rv3268
uniprot id: P96873
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Removed
up seq anno comments: TIGR03089 family protein
up seq anno feature ids: PRO_0000457299

83332:Rv1379
gene id: 83332:Rv1379
uniprot id: P9WHK3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Bifunctional protein PyrR
up seq anno comments: PRPP-binding
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000183046

83332:Rv0137c
gene id: 83332:Rv0137c
uniprot id: P9WJM5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Peptide methionine sulfoxide reductase MsrA
up seq anno feature ids: PRO_0000138560

83332:Rv3578
gene id: 83332:Rv3578
uniprot id: I6YCG9
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0489
gene id: 83332:Rv0489
uniprot id: P9WIC9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
up seq anno comments: Proton donor/acceptor
up seq anno comments: Tele-phosphohistidine intermediate
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000179893

83332:Rv0808
gene id: 83332:Rv0808
uniprot id: P9WHQ7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Propeptide
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Propeptide
up seq anno labels: Region
up seq anno comments: Amidophosphoribosyltransferase
up seq anno comments: Disordered
up seq anno comments: Glutamine amidotransferase type-2
up seq anno comments: Nucleophile
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000029257
up seq anno feature ids: PRO_0000029258

83332:Rv0282
gene id: 83332:Rv0282
uniprot id: P9WPI3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: ESX-3 secretion system protein EccA3
up seq anno feature ids: PRO_0000063045

83332:Rv0456c
gene id: 83332:Rv0456c
uniprot id: O07179
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1634
gene id: 83332:Rv1634
uniprot id: P9WJX3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable multidrug-efflux transporter Rv1634
up seq anno feature ids: PRO_0000390683

83332:Rv3903c
gene id: 83332:Rv3903c
uniprot id: O05442
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2-fold decrease in glycohydrolase activity. Intermediate cytotoxicity.
up seq anno comments: Decreases glycohydrolase activity and cytotoxicity in macrophages.
up seq anno comments: Disordered
up seq anno comments: Lack of glycohydrolase activity and of cytotoxicity; when associated with K-822.
up seq anno comments: Lack of glycohydrolase activity and of cytotoxicity; when associated with N-792.
up seq anno comments: N-terminal channel domain
up seq anno comments: NTD
up seq anno comments: Outer membrane channel protein CpnT
up seq anno comments: Pro residues
up seq anno comments: TNT
up seq anno comments: Tuberculosis necrotizing toxin
up seq anno comments: Unfolded. Lack of glycohydrolase activity. Abolishes toxicity.
up seq anno feature ids: PRO_0000437782
up seq anno feature ids: PRO_0000437783
up seq anno feature ids: PRO_0000437784

83332:Rv2863
gene id: 83332:Rv2863
uniprot id: P9WF89
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC23
up seq anno feature ids: PRO_0000407882

83332:Rv3396c
gene id: 83332:Rv3396c
uniprot id: P9WMS7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno comments: GMP synthase [glutamine-hydrolyzing]
up seq anno comments: GMPS ATP-PPase
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: N-acetylvaline
up seq anno comments: Nucleophile
up seq anno comments: Removed
up seq anno feature ids: PRO_0000140149

83332:Rv0106
gene id: 83332:Rv0106
uniprot id: P9WPI5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: CXCC motif
up seq anno comments: CobW C-terminal
up seq anno comments: Zinc chaperone Rv0106
up seq anno feature ids: PRO_0000103676

83332:Rv0599c
gene id: 83332:Rv0599c
uniprot id: O07779
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Antitoxin VapB27
up seq anno comments: SpoVT-AbrB
up seq anno feature ids: PRO_0000408044

83332:Rv3347c
gene id: 83332:Rv3347c
uniprot id: Q6MWX9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE

83332:Rv3547
gene id: 83332:Rv3547
uniprot id: P9WP15
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Deazaflavin-dependent nitroreductase
up seq anno comments: Loss of PA-824 and menadione reductase activity.
up seq anno comments: Loss of PA-824 reductase activity.
up seq anno feature ids: PRO_0000399507

83332:Rv2293c
gene id: 83332:Rv2293c
uniprot id: P9WLE1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2293c
up seq anno feature ids: PRO_0000014130

83332:Rv1623c
gene id: 83332:Rv1623c
uniprot id: L7N662
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Disulfide Bond
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0405
gene id: 83332:Rv0405
uniprot id: O86335
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv1265
gene id: 83332:Rv1265
uniprot id: P9WM49
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1265
up seq anno feature ids: PRO_0000103780

83332:Rv2958c
gene id: 83332:Rv2958c
uniprot id: P9WFR1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Disordered
up seq anno comments: PGL/p-HBAD biosynthesis glycosyltransferase Rv2958c
up seq anno feature ids: PRO_0000314436

83332:Rv0225
gene id: 83332:Rv0225
uniprot id: P96407
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Glycosyl transferase family 1
up seq anno comments: Glycosyltransferase subfamily 4-like N-terminal

83332:Rv2443
gene id: 83332:Rv2443
uniprot id: P71906
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1079
gene id: 83332:Rv1079
uniprot id: P9WGB7
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Cystathionine gamma-synthase
up seq anno comments: Disordered
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000114762

83332:Rv0714
gene id: 83332:Rv0714
uniprot id: P9WHD9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL14
up seq anno feature ids: PRO_0000128554

83332:Rv1906c
gene id: 83332:Rv1906c
uniprot id: O07726
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010288531

83332:Rv2260
gene id: 83332:Rv2260
uniprot id: O53534
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metallo-beta-lactamase

83332:Rv0898c
gene id: 83332:Rv0898c
uniprot id: P9WKP5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0898c
up seq anno feature ids: PRO_0000103739

83332:Rv3074
gene id: 83332:Rv3074
uniprot id: I6XG38
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HNH nuclease

83332:Rv2559c
gene id: 83332:Rv2559c
uniprot id: P9WQN1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized AAA domain-containing protein Rv2559c
up seq anno feature ids: PRO_0000104039

83332:Rv0578c
gene id: 83332:Rv0578c
uniprot id: Q6MX28
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0631c
gene id: 83332:Rv0631c
uniprot id: P9WIQ5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: RecBCD enzyme subunit RecC
up seq anno feature ids: PRO_0000087122

83332:Rv0294
gene id: 83332:Rv0294
uniprot id: P9WGA3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable trans-aconitate 2-methyltransferase
up seq anno feature ids: PRO_0000218082

83332:Rv2909c
gene id: 83332:Rv2909c
uniprot id: P9WH53
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Small ribosomal subunit protein bS16
up seq anno feature ids: PRO_0000167213

83332:Rv2390c
gene id: 83332:Rv2390c
uniprot id: P71754
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3225c
gene id: 83332:Rv3225c
uniprot id: O05841
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase

83332:Rv2873
gene id: 83332:Rv2873
uniprot id: P9WNF3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Glycosylation Site
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Glycosylation Site
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: Cell surface glycolipoprotein MPT83
up seq anno comments: FAS1
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: O-linked (Man...) threonine
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000008788

83332:Rv0117
gene id: 83332:Rv0117
uniprot id: L7N677
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH lysR-type

83332:Rv1303
gene id: 83332:Rv1303
uniprot id: P9WM31
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1303
up seq anno feature ids: PRO_0000103793

83332:Rv3044
gene id: 83332:Rv3044
uniprot id: O53291
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Fe/B12 periplasmic-binding
up seq anno feature ids: PRO_5039219144

83332:Rv3891c
gene id: 83332:Rv3891c
uniprot id: O05453
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxD
up seq anno feature ids: PRO_0000436931

83332:Rv1139c
gene id: 83332:Rv1139c
uniprot id: O06539
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0160c
gene id: 83332:Rv0160c
uniprot id: L7N661
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE-PPE

83332:Rv0530A
gene id: 83332:Rv0530A
uniprot id: V5QPR5
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv1962c
gene id: 83332:Rv1962c
uniprot id: P9WF67
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC35
up seq anno feature ids: PRO_0000407891

83332:Rv1605
gene id: 83332:Rv1605
uniprot id: P9WMM3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Imidazole glycerol phosphate synthase subunit HisF
up seq anno feature ids: PRO_0000142185

83332:Rv0235c
gene id: 83332:Rv0235c
uniprot id: P96418
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1423
gene id: 83332:Rv1423
uniprot id: P9WF45
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Initiator Methionine
up seq anno comments: H-T-H motif
up seq anno comments: Probable cell division protein WhiA
up seq anno comments: Removed
up seq anno feature ids: PRO_0000376534

83332:Rv2272
gene id: 83332:Rv2272
uniprot id: P9WLF5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2272
up seq anno feature ids: PRO_0000103999

83332:Rv2613c
gene id: 83332:Rv2613c
uniprot id: P9WMK9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: AP-4-A phosphorylase
up seq anno comments: Abolishes enzyme activity.
up seq anno comments: Disordered
up seq anno comments: HIT
up seq anno comments: Histidine triad motif
up seq anno comments: Reduces enzyme activity.
up seq anno comments: Tele-AMP-histidine intermediate
up seq anno feature ids: PRO_0000393106

83332:Rv1255c
gene id: 83332:Rv1255c
uniprot id: P9WMD5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv1255c
up seq anno feature ids: PRO_0000070660

83332:Rv3461c
gene id: 83332:Rv3461c
uniprot id: P9WH89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL36
up seq anno feature ids: PRO_0000126221

83332:Rv2078
gene id: 83332:Rv2078
uniprot id: P9WLK9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2078
up seq anno feature ids: PRO_0000103950

83332:Rv3278c
gene id: 83332:Rv3278c
uniprot id: P96883
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF304
up seq anno comments: Helical

83332:Rv0147
gene id: 83332:Rv0147
uniprot id: P96824
up seq anno parent labels: Active Site
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Aldehyde dehydrogenase
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2364c
gene id: 83332:Rv2364c
uniprot id: P9WNK9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Era-type G
up seq anno comments: G1
up seq anno comments: G2
up seq anno comments: G3
up seq anno comments: G4
up seq anno comments: G5
up seq anno comments: GTPase Era
up seq anno comments: KH type-2
up seq anno comments: N-acetylthreonine
up seq anno comments: No GTPase activity.
up seq anno comments: Removed
up seq anno feature ids: PRO_0000180031

83332:Rv1910c
gene id: 83332:Rv1910c
uniprot id: P9WFN5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: UPF0098 protein Rv1910c
up seq anno feature ids: PRO_0000137905

83332:Rv3589
gene id: 83332:Rv3589
uniprot id: P9WQ09
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: Adenine DNA glycosylase
up seq anno comments: HhH
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000421385

83332:Rv0819
gene id: 83332:Rv0819
uniprot id: P9WJM7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Mycothiol acetyltransferase
up seq anno comments: N-acetyltransferase 1
up seq anno comments: N-acetyltransferase 2
up seq anno feature ids: PRO_0000399828

83332:Rv2048c
gene id: 83332:Rv2048c
uniprot id: I6XD69
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Acyl-ester intermediate; for acyltransferase 1 activity
up seq anno comments: Acyl-ester intermediate; for acyltransferase 2 activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase 1 activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase 2 activity
up seq anno comments: Acyltransferase 1
up seq anno comments: Acyltransferase 2
up seq anno comments: Beta-ketoacyl reductase 1
up seq anno comments: Beta-ketoacyl reductase 2
up seq anno comments: C-terminal hotdog fold 1
up seq anno comments: C-terminal hotdog fold 2
up seq anno comments: Carrier 1
up seq anno comments: Carrier 2
up seq anno comments: Dehydratase 1
up seq anno comments: Dehydratase 2
up seq anno comments: Enoyl reductase 1
up seq anno comments: Enoyl reductase 2
up seq anno comments: For beta-ketoacyl reductase 1 activity
up seq anno comments: For beta-ketoacyl reductase 2 activity
up seq anno comments: For beta-ketoacyl synthase 1 activity
up seq anno comments: For beta-ketoacyl synthase 2 activity
up seq anno comments: Ketosynthase family 3 (KS3) 1
up seq anno comments: Ketosynthase family 3 (KS3) 2
up seq anno comments: Loss of activity.
up seq anno comments: Module 1
up seq anno comments: Module 2
up seq anno comments: Mycoketide-CoA synthase
up seq anno comments: N-terminal hotdog fold 1
up seq anno comments: N-terminal hotdog fold 2
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH 1
up seq anno comments: PKS/mFAS DH 2
up seq anno comments: Proton acceptor; for dehydratase activity 1
up seq anno comments: Proton acceptor; for dehydratase activity 2
up seq anno comments: Proton donor; for dehydratase activity 1
up seq anno comments: Proton donor; for dehydratase activity 2
up seq anno feature ids: PRO_0000451583

83332:Rv3407
gene id: 83332:Rv3407
uniprot id: P9WF23
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB47
up seq anno feature ids: PRO_0000104127

83332:Rv2231B
gene id: 83332:Rv2231B
uniprot id: P0CW31
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB16
up seq anno feature ids: PRO_0000408062

83332:Rv3468c
gene id: 83332:Rv3468c
uniprot id: Q6MWX3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD-dependent epimerase/dehydratase

83332:Rv2303c
gene id: 83332:Rv2303c
uniprot id: Q50662
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Amidohydrolase-related

83332:Rv1768
gene id: 83332:Rv1768
uniprot id: Q79FK9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv1445c
gene id: 83332:Rv1445c
uniprot id: P9WQP5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 6-phosphogluconolactonase
up seq anno feature ids: PRO_0000090101

83332:Rv0943c
gene id: 83332:Rv0943c
uniprot id: P9WKN7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0943c
up seq anno feature ids: PRO_0000103747

83332:Rv0415
gene id: 83332:Rv0415
uniprot id: P96261
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD dependent oxidoreductase

83332:Rv1275
gene id: 83332:Rv1275
uniprot id: O86337
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5039088695

83332:Rv2968c
gene id: 83332:Rv2968c
uniprot id: I6X5W1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Vitamin K epoxide reductase

83332:Rv2453c
gene id: 83332:Rv2453c
uniprot id: P9WJQ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable molybdenum cofactor guanylyltransferase
up seq anno feature ids: PRO_0000134894

83332:Rv1095
gene id: 83332:Rv1095
uniprot id: O53443
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PIN

83332:Rv0908
gene id: 83332:Rv0908
uniprot id: P9WPT1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Calcium-transporting ATPase CtpE
up seq anno comments: Helical
up seq anno feature ids: PRO_0000046341

83332:Rv3655c
gene id: 83332:Rv3655c
uniprot id: O69623
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Apoptosis inhibitor Rv3655c
up seq anno feature ids: PRO_0000438184

83332:Rv1392
gene id: 83332:Rv1392
uniprot id: P9WGV1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Flexible loop
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: S-adenosylmethionine synthase
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000174557

83332:Rv3616c
gene id: 83332:Rv3616c
uniprot id: P9WJE1
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Does not affect secretion, but inhibits disulfide bond formation. Alters mycobacterial cell wall integrity and significantly attenuates virulence.
up seq anno comments: ESX-1 secretion-associated protein EspA
up seq anno comments: Impairs EsxA and EsxB secretion in vitro. Modest impact on EspD stability and secretion. Attenuated in cellular models of tuberculosis infection.
up seq anno comments: Interchain
up seq anno comments: Severely destabilizes EspA and blocks ESX-1 secretion in vitro, but does not impact the cytotoxicity in cellular models of infection. Can induce pro-inflammatory responses in THP-1 cells and is as virulent as wild-type during the acute phase of infection in mice.
up seq anno comments: Severely destabilizes EspA and blocks ESX-1 secretion in vitro. Attenuated in cellular models of tuberculosis infection.
up seq anno feature ids: PRO_0000393903

83332:Rv3085
gene id: 83332:Rv3085
uniprot id: P9WGP9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative oxidoreductase SadH
up seq anno feature ids: PRO_0000420878

83332:Rv2571c
gene id: 83332:Rv2571c
uniprot id: P9WL89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative arylamide transporter
up seq anno feature ids: PRO_0000104052

83332:Rv0308
gene id: 83332:Rv0308
uniprot id: O07235
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Phosphatidic acid phosphatase type 2/haloperoxidase

83332:Rv3430c
gene id: 83332:Rv3430c
uniprot id: I6YC39
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Integrase catalytic
up seq anno comments: Polar residues

83332:Rv2059
gene id: 83332:Rv2059
uniprot id: O07257
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Basic residues
up seq anno comments: Disordered

83332:Rv2402
gene id: 83332:Rv2402
uniprot id: P71741
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Trehalase
up seq anno feature ids: PRO_0000413980

83332:Rv2920c
gene id: 83332:Rv2920c
uniprot id: P9WQ65
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Ammonium transporter
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno feature ids: PRO_0000139758

83332:Rv3238c
gene id: 83332:Rv3238c
uniprot id: O05883
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Methanethiol S-methyltransferase
up seq anno feature ids: PRO_0000444498

83332:Rv2886c
gene id: 83332:Rv2886c
uniprot id: P9WL35
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: O-(5'-phospho-DNA)-serine intermediate
up seq anno comments: Resolvase/invertase-type recombinase catalytic
up seq anno comments: Uncharacterized protein Rv2886c
up seq anno feature ids: PRO_0000104091

83332:Rv0128
gene id: 83332:Rv0128
uniprot id: P96805
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3055
gene id: 83332:Rv3055
uniprot id: P95103
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3532
gene id: 83332:Rv3532
uniprot id: P9WHX9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE61
up seq anno feature ids: PRO_0000379591

83332:Rv0265c
gene id: 83332:Rv0265c
uniprot id: L7N6B2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Fe/B12 periplasmic-binding

83332:Rv3909
gene id: 83332:Rv3909
uniprot id: O05436
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1803c
gene id: 83332:Rv1803c
uniprot id: Q79FJ9
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0425c
gene id: 83332:Rv0425c
uniprot id: P96271
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Cation-transporting P-type ATPase C-terminal
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv3557c
gene id: 83332:Rv3557c
uniprot id: P9WMB9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional repressor KstR2
up seq anno feature ids: PRO_0000405031

83332:Rv1973
gene id: 83332:Rv1973
uniprot id: P9WJ77
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Outer membrane protein Rv1973
up seq anno feature ids: PRO_0000415941

83332:Rv3558
gene id: 83332:Rv3558
uniprot id: Q6MWW0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE

83332:Rv0604
gene id: 83332:Rv0604
uniprot id: I6X9E2
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010314124

83332:Rv3737
gene id: 83332:Rv3737
uniprot id: O69704
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Probable threonine/serine exporter
up seq anno feature ids: PRO_0000456292

83332:Rv0246
gene id: 83332:Rv0246
uniprot id: O53668
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1434
gene id: 83332:Rv1434
uniprot id: O06824
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3180c
gene id: 83332:Rv3180c
uniprot id: P9WF51
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribonuclease VapC49
up seq anno feature ids: PRO_0000407897

83332:Rv2285
gene id: 83332:Rv2285
uniprot id: P9WKB5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv2285
up seq anno feature ids: PRO_0000222910

83332:Rv2089c
gene id: 83332:Rv2089c
uniprot id: P9WHS7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable dipeptidase PepE
up seq anno feature ids: PRO_0000185102

83332:Rv2582
gene id: 83332:Rv2582
uniprot id: P9WHW1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PPIase cyclophilin-type
up seq anno comments: Polar residues
up seq anno comments: Probable peptidyl-prolyl cis-trans isomerase B
up seq anno feature ids: PRO_0000064212

83332:Rv0161
gene id: 83332:Rv0161
uniprot id: O07406
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv1922
gene id: 83332:Rv1922
uniprot id: P95291
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Beta-lactamase-related

83332:Rv2759c
gene id: 83332:Rv2759c
uniprot id: P9WF57
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC42
up seq anno feature ids: PRO_0000221203

83332:Rv2413c
gene id: 83332:Rv2413c
uniprot id: P71730
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: Probable DNA polymerase III subunit delta
up seq anno comments: Removed
up seq anno feature ids: PRO_0000457297

83332:Rv3603c
gene id: 83332:Rv3603c
uniprot id: O06279
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF2520
up seq anno comments: Putative oxidoreductase/dehydrogenase Rossmann-like

83332:Rv2586c
gene id: 83332:Rv2586c
uniprot id: P9WGN9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Protein translocase subunit SecF
up seq anno feature ids: PRO_0000095983

83332:Rv3417c
gene id: 83332:Rv3417c
uniprot id: P9WPE9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cannot bind nickel, cobalt or copper.
up seq anno comments: Chaperonin GroEL 1
up seq anno comments: In strain: Erdman.
up seq anno comments: Lack of phosphorylation by PknF; when associated with A-25.
up seq anno comments: Lack of phosphorylation by PknF; when associated with A-54.
up seq anno comments: N-acetylserine
up seq anno comments: Phosphoserine; in tetradecamer
up seq anno comments: Phosphothreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000063451

83332:Rv1313c
gene id: 83332:Rv1313c
uniprot id: P9WKH7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Transposase for insertion sequence element IS1557
up seq anno feature ids: PRO_0000075450

83332:Rv0305c
gene id: 83332:Rv0305c
uniprot id: Q6MX48
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: PPE

83332:Rv1493
gene id: 83332:Rv1493
uniprot id: P9WJK5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: B12-binding
up seq anno comments: Probable methylmalonyl-CoA mutase large subunit
up seq anno comments: Transition state stabilizer
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000194270

83332:Rv2315c
gene id: 83332:Rv2315c
uniprot id: P71897
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Metalloprotease TldD/E C-terminal
up seq anno comments: Metalloprotease TldD/E N-terminal

83332:Rv0955
gene id: 83332:Rv0955
uniprot id: P9WKN3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0955
up seq anno feature ids: PRO_0000103751

83332:Rv1817
gene id: 83332:Rv1817
uniprot id: Q50616
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-dependent oxidoreductase 2 FAD binding

83332:Rv1285
gene id: 83332:Rv1285
uniprot id: P9WIK1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Sulfate adenylyltransferase subunit 2
up seq anno feature ids: PRO_0000100667

83332:Rv2978c
gene id: 83332:Rv2978c
uniprot id: I6Y263
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Cas12f1-like TNB
up seq anno comments: Disordered
up seq anno comments: Probable transposase IS891/IS1136/IS1341
up seq anno comments: Transposase putative helix-turn-helix

83332:Rv0775
gene id: 83332:Rv0775
uniprot id: P71830
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1610
gene id: 83332:Rv1610
uniprot id: O06128
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0573c
gene id: 83332:Rv0573c
uniprot id: P9WJI7
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Nicotinate phosphoribosyltransferase pncB2
up seq anno comments: Phosphohistidine
up seq anno feature ids: PRO_0000392685

83332:Rv3666c
gene id: 83332:Rv3666c
uniprot id: I6X811
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Solute-binding protein family 5

83332:Rv0175
gene id: 83332:Rv0175
uniprot id: O07419
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1745c
gene id: 83332:Rv1745c
uniprot id: P9WKK5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Isopentenyl-diphosphate Delta-isomerase
up seq anno comments: Nudix hydrolase
up seq anno feature ids: PRO_0000205254

83332:Rv3288c
gene id: 83332:Rv3288c
uniprot id: L7N685
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1405c
gene id: 83332:Rv1405c
uniprot id: P9WLY7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv1405c
up seq anno feature ids: PRO_0000014103

83332:Rv3095
gene id: 83332:Rv3095
uniprot id: P9WMG3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: HTH hxlR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv3095
up seq anno feature ids: PRO_0000148890

83332:Rv2070c
gene id: 83332:Rv2070c
uniprot id: P9WP89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Precorrin-6A reductase
up seq anno feature ids: PRO_0000135919

83332:Rv2930
gene id: 83332:Rv2930
uniprot id: P9WQ43
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Long-chain-fatty-acid--AMP ligase FadD26
up seq anno feature ids: PRO_0000193138

83332:Rv3249c
gene id: 83332:Rv3249c
uniprot id: O05892
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional regulator AlkX
up seq anno feature ids: PRO_0000458111

83332:Rv3779
gene id: 83332:Rv3779
uniprot id: P72045
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0975c
gene id: 83332:Rv0975c
uniprot id: O86319
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv0474
gene id: 83332:Rv0474
uniprot id: P9WMH9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0474
up seq anno feature ids: PRO_0000382635

83332:Rv3609c
gene id: 83332:Rv3609c
uniprot id: P9WN57
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: GTP cyclohydrolase 1
up seq anno feature ids: PRO_0000119423

83332:Rv3920c
gene id: 83332:Rv3920c
uniprot id: O53598
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: R3H

83332:Rv1940
gene id: 83332:Rv1940
uniprot id: L7N669
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: GTP cyclohydrolase II

83332:Rv0435c
gene id: 83332:Rv0435c
uniprot id: P96281
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AAA+ ATPase
up seq anno comments: CDC48 N-terminal subdomain

83332:Rv3569c
gene id: 83332:Rv3569c
uniprot id: P9WNH5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
up seq anno comments: Proton acceptor
up seq anno comments: Reduces the hydrolase activity.
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000404509

83332:Rv0800
gene id: 83332:Rv0800
uniprot id: P9WHT1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable M18 family aminopeptidase 2
up seq anno feature ids: PRO_0000173464

83332:Rv1985c
gene id: 83332:Rv1985c
uniprot id: P9WMF5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH lysR-type
up seq anno comments: HTH-type transcriptional regulator LysG
up seq anno comments: Leads to dissociation into monomers.
up seq anno feature ids: PRO_0000105812

83332:Rv3621c
gene id: 83332:Rv3621c
uniprot id: P9WHX3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE65
up seq anno feature ids: PRO_0000378487

83332:Rv0615
gene id: 83332:Rv0615
uniprot id: O07762
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3750c
gene id: 83332:Rv3750c
uniprot id: O69717
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB50
up seq anno feature ids: PRO_0000433059

83332:Rv3194c
gene id: 83332:Rv3194c
uniprot id: O53340
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Lon proteolytic
up seq anno comments: PDZ

83332:Rv0440
gene id: 83332:Rv0440
uniprot id: P9WPE7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes cleavage by Hip1.
up seq anno comments: Chaperonin GroEL 2
up seq anno comments: Cleavage by Hip1
up seq anno comments: Cleaved form
up seq anno comments: Disordered
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno feature ids: PRO_0000063452
up seq anno feature ids: PRO_0000453198

83332:Rv1107c
gene id: 83332:Rv1107c
uniprot id: P9WF29
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Exodeoxyribonuclease 7 small subunit
up seq anno feature ids: PRO_0000206975

83332:Rv3123
gene id: 83332:Rv3123
uniprot id: O07034
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv2101
gene id: 83332:Rv2101
uniprot id: I6YCF3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal

83332:Rv2629
gene id: 83332:Rv2629
uniprot id: P9WL63
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Sequence Variant
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Sequence Variant
up seq anno comments: Common variant in the Beijing-W clade/SCG-2 phylogenetic group.
up seq anno comments: Uncharacterized protein Rv2629
up seq anno feature ids: PRO_0000392936

83332:Rv2593c
gene id: 83332:Rv2593c
uniprot id: P9WGW3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acidic pin
up seq anno comments: Domain I
up seq anno comments: Domain II
up seq anno comments: Domain III
up seq anno comments: Flexible linker
up seq anno comments: Holliday junction branch migration complex subunit RuvA
up seq anno feature ids: PRO_0000094653

83332:Rv2950c
gene id: 83332:Rv2950c
uniprot id: P95141
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: 4-hydroxyphenylalkanoate adenylyltransferase
up seq anno feature ids: PRO_0000406357

83332:Rv1932
gene id: 83332:Rv1932
uniprot id: P9WG35
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes catalytic activity.
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: Increases catalytic activity.
up seq anno comments: Redox-active
up seq anno comments: Thiol peroxidase
up seq anno comments: Thioredoxin
up seq anno feature ids: PRO_0000187888

83332:Rv1591
gene id: 83332:Rv1591
uniprot id: P9WLT5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1591
up seq anno feature ids: PRO_0000103891

83332:Rv2773c
gene id: 83332:Rv2773c
uniprot id: P9WP23
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2.8-fold increase in catalytic activity with NADH as substrate, while the affinity for NADH is essentially unaffected. 70-fold decrease in affinity for NADPH, causing the nucleotide specificity to increase from 6:1 for the wild-type enzyme to 187:1.
up seq anno comments: 4-hydroxy-tetrahydrodipicolinate reductase
up seq anno comments: Increases the nucleotide specificity from 6:1 for the wild-type enzyme to 34:1, due to a 4-fold decrease in NADPH affinity while the affinity for NADH remains nearly unchanged.
up seq anno comments: Proton donor
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000141458

83332:Rv2423
gene id: 83332:Rv2423
uniprot id: P71925
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv2597
gene id: 83332:Rv2597
uniprot id: P9WL73
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2597
up seq anno feature ids: PRO_0000104065

83332:Rv0754
gene id: 83332:Rv0754
uniprot id: Q79FW5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Lack of phosphoglycerate mutase activity.
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS11
up seq anno comments: Phosphoglycerate mutase
up seq anno comments: Proton donor/acceptor
up seq anno comments: Tele-phosphohistidine intermediate
up seq anno feature ids: PRO_5004287637

83332:Rv3436c
gene id: 83332:Rv3436c
uniprot id: P9WN49
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno comments: For Fru-6P isomerization activity
up seq anno comments: Glutamine amidotransferase type-2
up seq anno comments: Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
up seq anno comments: Nucleophile; for GATase activity
up seq anno comments: Removed
up seq anno comments: SIS 1
up seq anno comments: SIS 2
up seq anno feature ids: PRO_0000135357

83332:Rv3066
gene id: 83332:Rv3066
uniprot id: I6X658
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv0442c
gene id: 83332:Rv0442c
uniprot id: P9WI41
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Disordered
up seq anno comments: PPE family protein PPE10
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000217843

83332:Rv2891
gene id: 83332:Rv2891
uniprot id: P9WL33
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv2891
up seq anno feature ids: PRO_0000014147

83332:Rv1995
gene id: 83332:Rv1995
uniprot id: P9WLP3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1995
up seq anno feature ids: PRO_0000103922

83332:Rv0965c
gene id: 83332:Rv0965c
uniprot id: P9WKM3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0965c
up seq anno feature ids: PRO_0000103763

83332:Rv2718c
gene id: 83332:Rv2718c
uniprot id: P9WIZ1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Zinc Finger
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Zinc Finger
up seq anno comments: ATP-cone
up seq anno comments: Transcriptional repressor NrdR
up seq anno feature ids: PRO_0000182321

83332:Rv1828
gene id: 83332:Rv1828
uniprot id: P9WME7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: H-T-H motif
up seq anno comments: HTH merR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv1828
up seq anno feature ids: PRO_0000098168

83332:Rv2988c
gene id: 83332:Rv2988c
uniprot id: P9WQF5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 3-isopropylmalate dehydratase large subunit
up seq anno feature ids: PRO_0000076766

83332:Rv1620c
gene id: 83332:Rv1620c
uniprot id: O06137
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Helical

83332:Rv2115c
gene id: 83332:Rv2115c
uniprot id: P9WQN5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Abolishes proteasome substrate degradation and protection against RNI.
up seq anno comments: Abolishes proteasome substrate degradation.
up seq anno comments: Abolishes protection against RNI.
up seq anno comments: Abolishes unfolding capacity.
up seq anno comments: Disordered
up seq anno comments: Docks into pockets in the proteasome alpha-ring
up seq anno comments: Does not dramatically affect proteasome substrate degradation.
up seq anno comments: Impairs Mpa hexamerization; when associated with A-187 and E-235.
up seq anno comments: Impairs Mpa hexamerization; when associated with E-173 and A-187.
up seq anno comments: Impairs Mpa hexamerization; when associated with E-173 and E-235.
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: No effect on unfolding capacity.
up seq anno comments: Proteasome-associated ATPase
up seq anno comments: Reduces both ATPase activity and ATP affinity. Abolishes proteasome substrate degradation and protection against RNI.
up seq anno comments: Retains ATPase and unfolding activities, yet abolishes proteasome substrate degradation and protection against RNI. Is also highly attenuated in mice.
up seq anno comments: Severely reduces ATPase activity. Abolishes proteasome substrate degradation and protection against RNI.
up seq anno comments: Severely reduces ATPase activity. Abolishes protection against RNI.
up seq anno feature ids: PRO_0000084778

83332:Rv0584
gene id: 83332:Rv0584
uniprot id: O86365
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized glycosidase Rv0584
up seq anno feature ids: PRO_0000415515

83332:Rv3676
gene id: 83332:Rv3676
uniprot id: P9WMH3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: CRP-like cAMP-activated global transcriptional regulator
up seq anno comments: H-T-H motif
up seq anno comments: HTH crp-type
up seq anno feature ids: PRO_0000420402

83332:Rv1449c
gene id: 83332:Rv1449c
uniprot id: P9WG25
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Important for catalytic activity
up seq anno comments: N-acetylthreonine
up seq anno comments: Proton donor
up seq anno comments: Removed
up seq anno comments: Transketolase
up seq anno feature ids: PRO_0000191863

83332:Rv2290
gene id: 83332:Rv2290
uniprot id: P9WK71
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppO
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018114

83332:Rv1760
gene id: 83332:Rv1760
uniprot id: P9WKB9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv1760
up seq anno feature ids: PRO_0000222909

83332:Rv1415
gene id: 83332:Rv1415
uniprot id: P9WHF1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Site
up seq anno comments: DHBP synthase
up seq anno comments: Essential for DHBP synthase activity
up seq anno comments: GTP cyclohydrolase II
up seq anno comments: Nucleophile; for GTP cyclohydrolase activity
up seq anno comments: Proton acceptor; for GTP cyclohydrolase activity
up seq anno comments: Riboflavin biosynthesis protein RibBA
up seq anno feature ids: PRO_0000151728

83332:Rv1943c
gene id: 83332:Rv1943c
uniprot id: P9WJ89
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin MazE5
up seq anno feature ids: PRO_0000406299

83332:Rv3106
gene id: 83332:Rv3106
uniprot id: P9WIQ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: NADPH-ferredoxin reductase FprA
up seq anno comments: No effect on activity. Decreases Km for NADP 2-fold.
up seq anno comments: Reduces activity 4-fold.
up seq anno feature ids: PRO_0000087329

83332:Rv2940c
gene id: 83332:Rv2940c
uniprot id: I6Y231
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Carrier
up seq anno comments: Ketosynthase family 3 (KS3)

83332:Rv2080
gene id: 83332:Rv2080
uniprot id: P9WK77
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Putative lipoprotein LppJ
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018108

83332:Rv0845
gene id: 83332:Rv0845
uniprot id: O53857
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Transmembrane
up seq anno comments: Complete loss of autophosphorylation.
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Sensor histidine kinase NarS
up seq anno feature ids: PRO_0000401133

83332:Rv3791
gene id: 83332:Rv3791
uniprot id: P9WGS9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Decaprenylphosphoryl-2-keto-beta-D-erythro-pentose reductase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000054860

83332:Rv0988
gene id: 83332:Rv0988
uniprot id: O86370
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AttH

83332:Rv0484c
gene id: 83332:Rv0484c
uniprot id: P9WGR5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv0484c
up seq anno feature ids: PRO_0000054863

83332:Rv3620c
gene id: 83332:Rv3620c
uniprot id: P9WNI3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxW
up seq anno feature ids: PRO_0000167816

83332:Rv0810c
gene id: 83332:Rv0810c
uniprot id: I6XWB9
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv3761c
gene id: 83332:Rv3761c
uniprot id: O69727
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Aminoglycoside phosphotransferase

83332:Rv0270
gene id: 83332:Rv0270
uniprot id: P95227
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv0691A
gene id: 83332:Rv0691A
uniprot id: P9WJ81
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Cleavage; by MftE
up seq anno comments: Mycofactocin precursor peptide
up seq anno feature ids: PRO_0000415282

83332:Rv1290c
gene id: 83332:Rv1290c
uniprot id: P9WM35
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1290c
up seq anno feature ids: PRO_0000103789

83332:Rv0933
gene id: 83332:Rv0933
uniprot id: P9WQK9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno comments: ABC transporter
up seq anno comments: Phosphate import ATP-binding protein PstB 2
up seq anno feature ids: PRO_0000092850

83332:Rv1773c
gene id: 83332:Rv1773c
uniprot id: O06806
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH iclR-type
up seq anno comments: IclR-ED

83332:Rv2640c
gene id: 83332:Rv2640c
uniprot id: I6Y1A7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH arsR-type

83332:Rv0743c
gene id: 83332:Rv0743c
uniprot id: I6WZ83
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF6036

83332:Rv3878
gene id: 83332:Rv3878
uniprot id: P9WJC3
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion-associated protein EspJ
up seq anno comments: Lack of phosphorylation. Increases the growth of mycobacteria.
up seq anno comments: Phosphoserine
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000394148

83332:Rv1602
gene id: 83332:Rv1602
uniprot id: P9WMM1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: Imidazole glycerol phosphate synthase subunit HisH
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000152396

83332:Rv2783c
gene id: 83332:Rv2783c
uniprot id: P9WI57
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: KH
up seq anno comments: Polyribonucleotide nucleotidyltransferase
up seq anno comments: S1 motif
up seq anno feature ids: PRO_0000329724

83332:Rv3295
gene id: 83332:Rv3295
uniprot id: P96900
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv0506
gene id: 83332:Rv0506
uniprot id: P9WJT3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport accessory protein MmpS2
up seq anno feature ids: PRO_0000216153

83332:Rv0841
gene id: 83332:Rv0841
uniprot id: I6WZK3
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0333
gene id: 83332:Rv0333
uniprot id: O33273
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv1717
gene id: 83332:Rv1717
uniprot id: O86372
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Beta-D-galactosidase Rv1717
up seq anno comments: Cupin type-2
up seq anno feature ids: PRO_0000456475

83332:Rv2902c
gene id: 83332:Rv2902c
uniprot id: P9WH01
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: RNase H type-2
up seq anno comments: Ribonuclease HII
up seq anno feature ids: PRO_0000111592

83332:Rv1515c
gene id: 83332:Rv1515c
uniprot id: P71794
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv0144
gene id: 83332:Rv0144
uniprot id: P96821
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3771c
gene id: 83332:Rv3771c
uniprot id: P72038
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3739c
gene id: 83332:Rv3739c
uniprot id: Q79FA2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE

83332:Rv0628c
gene id: 83332:Rv0628c
uniprot id: P9WKS7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0628c
up seq anno feature ids: PRO_0000103714

83332:Rv2057c
gene id: 83332:Rv2057c
uniprot id: P9WH97
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL33A
up seq anno feature ids: PRO_0000170194

83332:Rv0451c
gene id: 83332:Rv0451c
uniprot id: P9WJS9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Siderophore export accessory protein MmpS4
up seq anno feature ids: PRO_0000216158

83332:Rv2662
gene id: 83332:Rv2662
uniprot id: P71959
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1631
gene id: 83332:Rv1631
uniprot id: P9WPA3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Almost loss of activity. Shows very poor binding to ATP.
up seq anno comments: DPCK
up seq anno comments: Decreases Km for both ATP and dephospho-CoA. Has minimal effect on kcat.
up seq anno comments: Dephospho-CoA kinase
up seq anno comments: Does not affect Km for ATP, but shows a 15-fold increase in the Km for dephospho-CoA. Decrease in kcat and strong decrease in catalytic efficiency.
up seq anno comments: Does not affect Km for ATP, but shows a 2.5-fold increase in the Km for dephospho-CoA.
up seq anno comments: Does not affect oligomerization.
up seq anno comments: Does not change either the Km or the kcat of the reaction considerably.
up seq anno comments: Increases Km for both ATP and dephospho-CoA, but increases the enzymatic turnover.
up seq anno comments: Loss of activity.
up seq anno comments: Shows a 50% increase in the Km for ATP and a 19% reduction in kcat.
up seq anno comments: UPF0157
up seq anno feature ids: PRO_0000172964

83332:Rv3425
gene id: 83332:Rv3425
uniprot id: Q50703
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: PPE family protein PPE57
up seq anno feature ids: PRO_0000217853

83332:Rv0096
gene id: 83332:Rv0096
uniprot id: P9WI49
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized PPE family protein PPE1
up seq anno feature ids: PRO_0000217842

83332:Rv2494
gene id: 83332:Rv2494
uniprot id: O53219
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Ribonuclease VapC38
up seq anno feature ids: PRO_0000407893

83332:Rv3888c
gene id: 83332:Rv3888c
uniprot id: O05456
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1133c
gene id: 83332:Rv1133c
uniprot id: P9WK07
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
up seq anno comments: Disordered
up seq anno comments: Polar residues
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000098641

83332:Rv3687c
gene id: 83332:Rv3687c
uniprot id: P9WGE1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno comments: Anti-sigma-F factor antagonist RsfB
up seq anno comments: No longer interacts with RsbW.
up seq anno comments: Phosphoserine
up seq anno comments: STAS
up seq anno comments: Still interacts with RsbW.
up seq anno feature ids: PRO_0000422956

83332:Rv1461
gene id: 83332:Rv1461
uniprot id: P9WFP7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: DOD-type homing endonuclease
up seq anno comments: Disordered
up seq anno comments: Endonuclease PI-MtuHIIP
up seq anno comments: UPF0051 protein Rv1461, 1st part
up seq anno comments: UPF0051 protein Rv1461, 2nd part
up seq anno feature ids: PRO_0000036190
up seq anno feature ids: PRO_0000036191
up seq anno feature ids: PRO_0000036192

83332:Rv0596c
gene id: 83332:Rv0596c
uniprot id: P9WF21
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Antitoxin VapB4
up seq anno comments: No effect. No longer neutralizes VapC4 in full-length VapB4; when associated with G-48; R-48 or E-54.
up seq anno comments: No effect. No longer neutralizes VapC4 in full-length VapB4; when associated with low levels of G-48.
up seq anno comments: No effect. No longer neutralizes VapC4 in full-length antitoxin, decreased interaction with VapC4 (tested for G-48 only); when associated with A-64.
up seq anno comments: No effect. No longer neutralizes VapC4 in full-length antitoxin; when associated with A-64.
up seq anno comments: No longer neutralizes VapC4 in full-length VapB4; when associated with low levels of G-48.
up seq anno comments: Not required to interact with or neutralize cognate toxin VapC4
up seq anno comments: Sufficient to interact with and neutralize VapC4
up seq anno feature ids: PRO_0000408045

83332:Rv2300c
gene id: 83332:Rv2300c
uniprot id: P9WLD7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Probable metallo-hydrolase Rv2300c
up seq anno feature ids: PRO_0000104009

83332:Rv1954c
gene id: 83332:Rv1954c
uniprot id: P9WLQ3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1954c
up seq anno feature ids: PRO_0000103915

83332:Rv2133c
gene id: 83332:Rv2133c
uniprot id: O06242
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein Rv2133c
up seq anno feature ids: PRO_0000456390

83332:Rv2091c
gene id: 83332:Rv2091c
uniprot id: P9WLJ5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized protein Rv2091c
up seq anno feature ids: PRO_0000103961

83332:Rv2609c
gene id: 83332:Rv2609c
uniprot id: I6YDV4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Nudix hydrolase

83332:Rv3802c
gene id: 83332:Rv3802c
uniprot id: O53581
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 2-fold decrease in kcat for 4-methylumbelliferyl heptanoate and loss of phopholipase A activity; when associated with C-132.
up seq anno comments: 2-fold decrease in kcat for 4-methylumbelliferyl heptanoate and loss of phopholipase A activity; when associated with C-288.
up seq anno comments: Carboxylesterase/lipase Culp6
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Loss of activity for both short- and long-chain substrates.
up seq anno comments: Nucleophile
up seq anno comments: Pro residues
up seq anno comments: Proton donor/acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000450109

83332:Rv2428
gene id: 83332:Rv2428
uniprot id: P9WQB7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 50% reduction in oxidation activity of dithiothreitol and 60% reduction in oxidation of thiocyanate.
up seq anno comments: 50% reduction in oxidation activity of dithiothreitol and thiocyanate.
up seq anno comments: Alkyl hydroperoxide reductase C
up seq anno comments: Cysteine sulfenic acid (-SOH) intermediate
up seq anno comments: In reconstituted in vitro system retains no enzyme activity.
up seq anno comments: Interchain (with C-133 in AhpD); transient
up seq anno comments: Interchain (with C-174); in linked form
up seq anno comments: Interchain (with C-61); in linked form
up seq anno comments: No enzyme activity.
up seq anno comments: Removed
up seq anno comments: Retains about 10% activity with tert-butylhydroperoxide. In reconstituted in vitro system retains 30% enzyme activity.
up seq anno comments: Thioredoxin
up seq anno comments: Very poor oxidation activity of dithiothreitol and thiocyanate.
up seq anno feature ids: PRO_0000392913

83332:Rv1525
gene id: 83332:Rv1525
uniprot id: P9WLV3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1525
up seq anno feature ids: PRO_0000103870

83332:Rv2750
gene id: 83332:Rv2750
uniprot id: P9WGS5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv2750
up seq anno feature ids: PRO_0000416412

83332:Rv3632
gene id: 83332:Rv3632
uniprot id: I6YGT7
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0495c
gene id: 83332:Rv0495c
uniprot id: P9WKU5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0495c
up seq anno feature ids: PRO_0000103695

83332:Rv2340c
gene id: 83332:Rv2340c
uniprot id: L7N659
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0532
gene id: 83332:Rv0532
uniprot id: L0T3X8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv1165
gene id: 83332:Rv1165
uniprot id: O06563
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Tr-type G

83332:Rv0291
gene id: 83332:Rv0291
uniprot id: O53695
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Charge relay system
up seq anno comments: Helical
up seq anno comments: Mycosin-3
up seq anno comments: Peptidase S8
up seq anno feature ids: PRO_5007697062

83332:Rv1641
gene id: 83332:Rv1641
uniprot id: P9WKJ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Translation initiation factor IF-3
up seq anno feature ids: PRO_0000177546

83332:Rv1129c
gene id: 83332:Rv1129c
uniprot id: O06581
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: H-T-H motif
up seq anno comments: HTH cro/C1-type
up seq anno comments: HTH-type transcriptional regulator PrpR
up seq anno feature ids: PRO_0000433054

83332:Rv0114
gene id: 83332:Rv0114
uniprot id: P9WMV3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Contributes to substrate recognition
up seq anno comments: D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno comments: Stabilizes the phosphoryl group
up seq anno feature ids: PRO_0000209397

83332:Rv1300
gene id: 83332:Rv1300
uniprot id: P9WHV3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Release factor glutamine methyltransferase
up seq anno feature ids: PRO_0000157166

83332:Rv1473
gene id: 83332:Rv1473
uniprot id: O53164
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv0945
gene id: 83332:Rv0945
uniprot id: P9WGR7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized oxidoreductase Rv0945
up seq anno feature ids: PRO_0000054862

83332:Rv1785c
gene id: 83332:Rv1785c
uniprot id: P9WPL3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Cytochrome P450 143
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052306

83332:Rv2652c
gene id: 83332:Rv2652c
uniprot id: P71949
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1715
gene id: 83332:Rv1715
uniprot id: L7N688
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: 3-hydroxyacyl-CoA dehydrogenase C-terminal
up seq anno comments: 3-hydroxyacyl-CoA dehydrogenase NAD binding
up seq anno comments: Important for catalytic activity

83332:Rv1612
gene id: 83332:Rv1612
uniprot id: P9WFX9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Removed
up seq anno comments: Tryptophan synthase beta chain
up seq anno feature ids: PRO_0000098969

83332:Rv2450c
gene id: 83332:Rv2450c
uniprot id: O53177
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: Pro residues
up seq anno comments: Resuscitation-promoting factor RpfE
up seq anno feature ids: PRO_0000421031

83332:Rv3307
gene id: 83332:Rv3307
uniprot id: P9WP01
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Purine nucleoside phosphorylase
up seq anno feature ids: PRO_0000184544

83332:Rv0517
gene id: 83332:Rv0517
uniprot id: O33362
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Acyltransferase 3
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv2269c
gene id: 83332:Rv2269c
uniprot id: P9WLF9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2269c
up seq anno feature ids: PRO_0000103995

83332:Rv0935
gene id: 83332:Rv0935
uniprot id: P9WG07
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Phosphate transport system permease protein PstC 1
up seq anno feature ids: PRO_0000060218

83332:Rv3458c
gene id: 83332:Rv3458c
uniprot id: P9WH35
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: S4 RNA-binding
up seq anno comments: Small ribosomal subunit protein uS4
up seq anno feature ids: PRO_0000132422

83332:Rv3087
gene id: 83332:Rv3087
uniprot id: P9WKB1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Proton acceptor
up seq anno comments: Putative diacyglycerol O-acyltransferase Rv3087
up seq anno feature ids: PRO_0000222913

83332:Rv3644c
gene id: 83332:Rv3644c
uniprot id: O06363
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno comments: AAA+ ATPase

83332:Rv0344c
gene id: 83332:Rv0344c
uniprot id: O06295
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Pro residues
up seq anno feature ids: PRO_5010230426

83332:Rv1727
gene id: 83332:Rv1727
uniprot id: P71985
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Mycothiol-dependent maleylpyruvate isomerase metal-binding

83332:Rv3275c
gene id: 83332:Rv3275c
uniprot id: P9WHM1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N5-carboxyaminoimidazole ribonucleotide mutase
up seq anno feature ids: PRO_0000074977

83332:Rv3781
gene id: 83332:Rv3781
uniprot id: P72047
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ABC transporter

83332:Rv3873
gene id: 83332:Rv3873
uniprot id: P9WHW9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Acidic residues
up seq anno comments: Disordered
up seq anno comments: PPE family immunomodulator PPE68
up seq anno feature ids: PRO_0000379593

83332:Rv0639
gene id: 83332:Rv0639
uniprot id: P9WIU9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Transcription termination/antitermination protein NusG
up seq anno feature ids: PRO_0000113936

83332:Rv2399c
gene id: 83332:Rv2399c
uniprot id: P71745
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv2162c
gene id: 83332:Rv2162c
uniprot id: L7N6A1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv3586
gene id: 83332:Rv3586
uniprot id: P9WNW5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Abolishes ATP-binding and diadenylate cyclase activity.
up seq anno comments: DAC
up seq anno comments: DNA integrity scanning protein DisA
up seq anno comments: Retains diadenylate cyclase activity.
up seq anno feature ids: PRO_0000424180

83332:Rv0463
gene id: 83332:Rv0463
uniprot id: O53748
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1310
gene id: 83332:Rv1310
uniprot id: P9WPU5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: ATP synthase subunit beta
up seq anno comments: Disordered
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000144455

83332:Rv0469
gene id: 83332:Rv0469
uniprot id: Q6MX39
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: S-adenosylmethionine-dependent methyltransferase UmaA
up seq anno feature ids: PRO_0000434597

83332:Rv0276
gene id: 83332:Rv0276
uniprot id: O53682
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic

83332:Rv3404c
gene id: 83332:Rv3404c
uniprot id: P9WKZ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Proton acceptor
up seq anno comments: dTDP-4-amino-4,6-dideoxyglucose formyltransferase
up seq anno feature ids: PRO_0000014151

83332:Rv0164
gene id: 83332:Rv0164
uniprot id: L7N657
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Coenzyme Q-binding protein COQ10 START

83332:Rv2504c
gene id: 83332:Rv2504c
uniprot id: P9WPW5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A
up seq anno feature ids: PRO_0000157911

83332:Rv3900c
gene id: 83332:Rv3900c
uniprot id: O05445
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1146
gene id: 83332:Rv1146
uniprot id: O06546
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Membrane transport protein MMPL

83332:Rv2312
gene id: 83332:Rv2312
uniprot id: P9WLB9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2312
up seq anno feature ids: PRO_0000104022

83332:Rv1155a
gene id: 83332:Rv1155a
uniprot id: A0A089QKZ7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1155A
up seq anno feature ids: PRO_0000434780

83332:Rv2793c
gene id: 83332:Rv2793c
uniprot id: P9WHP7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Nucleophile
up seq anno comments: tRNA pseudouridine synthase B
up seq anno feature ids: PRO_0000121872

83332:Rv0038
gene id: 83332:Rv0038
uniprot id: P9WFK5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: UPF0301 protein Rv0038
up seq anno feature ids: PRO_0000214329

83332:Rv1431
gene id: 83332:Rv1431
uniprot id: O06827
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2965c
gene id: 83332:Rv2965c
uniprot id: P9WPA5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: N-acetylthreonine
up seq anno comments: Phosphopantetheine adenylyltransferase
up seq anno comments: Removed
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000156242

83332:Rv1262c
gene id: 83332:Rv1262c
uniprot id: P9WML1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: HIT
up seq anno comments: Histidine triad motif
up seq anno comments: Uncharacterized HIT-like protein Rv1262c
up seq anno feature ids: PRO_0000109826

83332:Rv3815c
gene id: 83332:Rv3815c
uniprot id: O07808
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv3469c
gene id: 83332:Rv3469c
uniprot id: O06334
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: Oxaloacetate decarboxylase
up seq anno comments: Pyruvate carboxyltransferase
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000450804

83332:Rv2440c
gene id: 83332:Rv2440c
uniprot id: P9WMT1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: GTPase Obg
up seq anno comments: No GTPase activity.
up seq anno comments: OBG-type G
up seq anno comments: OCT
up seq anno comments: Obg
up seq anno feature ids: PRO_0000386062

83332:Rv2797c
gene id: 83332:Rv2797c
uniprot id: P71654
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3285
gene id: 83332:Rv3285
uniprot id: P96890
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-grasp
up seq anno comments: Biotin carboxylation
up seq anno comments: Biotin-dependent acyl-coenzyme A carboxylase alpha3 subunit
up seq anno comments: Biotinyl-binding
up seq anno comments: N6-biotinyllysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000452367

83332:Rv2761c
gene id: 83332:Rv2761c
uniprot id: I6YEB1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Type I restriction modification DNA specificity

83332:Rv2257c
gene id: 83332:Rv2257c
uniprot id: O53531
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Beta-lactamase-related

83332:Rv0156
gene id: 83332:Rv0156
uniprot id: P96833
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NAD(P) transhydrogenase alpha subunit C-terminal

83332:Rv2401A
gene id: 83332:Rv2401A
uniprot id: Q79FE4
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2196
gene id: 83332:Rv2196
uniprot id: P9WP37
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Confers resistance to LPZS. Remains susceptible to IPA.
up seq anno comments: Confers resistance to Q203 and IPA. Remains susceptible to LPZS.
up seq anno comments: Cytochrome bc1 complex cytochrome b subunit
up seq anno comments: Helical
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000061927

83332:Rv1178
gene id: 83332:Rv1178
uniprot id: O50434
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Probable aminotransferase Rv1178
up seq anno feature ids: PRO_0000456392

83332:Rv1653
gene id: 83332:Rv1653
uniprot id: P9WPZ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno comments: Arginine biosynthesis bifunctional protein ArgJ alpha chain
up seq anno comments: Arginine biosynthesis bifunctional protein ArgJ beta chain
up seq anno comments: Cleavage; by autolysis
up seq anno comments: Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000002193
up seq anno feature ids: PRO_0000002194

83332:Rv3414c
gene id: 83332:Rv3414c
uniprot id: P9WGG9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: ECF RNA polymerase sigma factor SigD
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000094023

83332:Rv0654
gene id: 83332:Rv0654
uniprot id: P9WPR5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Carotenoid cleavage oxygenase
up seq anno feature ids: PRO_0000420620

83332:Rv0125
gene id: 83332:Rv0125
uniprot id: O07175
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PDZ
up seq anno feature ids: PRO_5010226728

83332:Rv1845c
gene id: 83332:Rv1845c
uniprot id: P95164
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Peptidase M48

83332:Rv1484
gene id: 83332:Rv1484
uniprot id: P9WGR1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1500-fold decrease in catalytic activity while no effect on lipid substrate affinity.
up seq anno comments: 24-fold decrease in catalytic activity while no effect on lipid substrate affinity.
up seq anno comments: Confers INH and ETH resistance. The mutant is 17 times more resistant to inhibition by the INH-NAD adduct. 5- to 6-fold decrease in affinity for NADH that results from a perturbation in the hydrogen-bonding network that stabilizes NADH binding. Nearly no effect on the velocity of the enzyme. Has no impact on the susceptibility to pyridomycin.
up seq anno comments: Confers pyridomycin resistance. Has no impact on the susceptibility to isoniazid and moxifloxacin. 14-fold decrease in NADH affinity, while no effect on catalytic activity.
up seq anno comments: Enoyl-[acyl-carrier-protein] reductase [NADH]
up seq anno comments: Loss of enzyme's ability to bind NADH.
up seq anno comments: May act as an intermediate that passes the hydride ion from NADH to the substrate
up seq anno comments: No effect on catalytic activity.
up seq anno comments: No effect on catalytic activity. Loss of phosphorylation. Does not alter growth of M.tuberculosis.
up seq anno comments: No effect on the enzyme's catalytic ability or on its ability to bind NADH.
up seq anno comments: Phosphothreonine
up seq anno comments: Severely impairs catalytic activity, as a consequence of a reduced binding affinity to NADH. These single point mutations are lethal to M.tuberculosis. These mutants fail to complement growth and mycolic acid defects of an inhA-thermosensitive M.smegmatis strain, in a similar manner to what is observed following isoniazid treatment.
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000054916

83332:Rv0620
gene id: 83332:Rv0620
uniprot id: P9WN63
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Galactokinase
up seq anno comments: Proton acceptor
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000184619

83332:Rv1810
gene id: 83332:Rv1810
uniprot id: O07222
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: DUF732
up seq anno feature ids: PRO_5004157079

83332:Rv1800
gene id: 83332:Rv1800
uniprot id: P9WI11
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE-PPE
up seq anno comments: Uncharacterized PPE family protein PPE28
up seq anno feature ids: PRO_0000379111

83332:Rv1622c
gene id: 83332:Rv1622c
uniprot id: O06139
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2144c
gene id: 83332:Rv2144c
uniprot id: O06231
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2460c
gene id: 83332:Rv2460c
uniprot id: P9WPC3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ATP-dependent Clp protease proteolytic subunit 2
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000179597

83332:Rv3317
gene id: 83332:Rv3317
uniprot id: O53369
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv0243
gene id: 83332:Rv0243
uniprot id: O86361
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Proton acceptor
up seq anno comments: Thiolase C-terminal
up seq anno comments: Thiolase N-terminal

83332:Rv3826
gene id: 83332:Rv3826
uniprot id: P9WQ47
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Helical
up seq anno comments: Long-chain-fatty-acid--AMP ligase FadD23
up seq anno feature ids: PRO_0000406793

83332:Rv2282c
gene id: 83332:Rv2282c
uniprot id: P9WMF3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH lysR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv2282c
up seq anno feature ids: PRO_0000105814

83332:Rv2096c
gene id: 83332:Rv2096c
uniprot id: P9WIM1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Protein PafB
up seq anno feature ids: PRO_0000103963

83332:Rv3657c
gene id: 83332:Rv3657c
uniprot id: O69625
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Type II secretion system protein GspF

83332:Rv1737c
gene id: 83332:Rv1737c
uniprot id: P9WJY7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable nitrate/nitrite transporter NarK2
up seq anno feature ids: PRO_0000392910

83332:Rv1188
gene id: 83332:Rv1188
uniprot id: O50444
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Proline dehydrogenase

83332:Rv2410c
gene id: 83332:Rv2410c
uniprot id: P71733
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DUF403

83332:Rv3600c
gene id: 83332:Rv3600c
uniprot id: P9WPA1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Type III pantothenate kinase
up seq anno feature ids: PRO_0000267566

83332:Rv0827c
gene id: 83332:Rv0827c
uniprot id: O53838
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH arsR-type
up seq anno comments: HTH-type transcriptional regulator KmtR
up seq anno comments: No change in activity. Does not affect regulation by metal ions.
up seq anno comments: No change in activity. Lack of regulation by metal ions.
up seq anno feature ids: PRO_0000419178

83332:Rv0476
gene id: 83332:Rv0476
uniprot id: P9WKW1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0476
up seq anno feature ids: PRO_0000014071

83332:Rv1320c
gene id: 83332:Rv1320c
uniprot id: P9WQ29
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Guanylate cyclase
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1320c
up seq anno feature ids: PRO_0000195756

83332:Rv3062
gene id: 83332:Rv3062
uniprot id: P9WNV5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: DNA ligase B
up seq anno comments: N6-AMP-lysine intermediate
up seq anno comments: Not required for adenylyltransferase activity, required for nick joining
up seq anno feature ids: PRO_0000365231

83332:Rv3911
gene id: 83332:Rv3911
uniprot id: O53590
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: ECF RNA polymerase sigma factor SigM
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000420400

83332:Rv1157c
gene id: 83332:Rv1157c
uniprot id: O06555
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Pro residues
up seq anno feature ids: PRO_5038958497

83332:Rv2142A
gene id: 83332:Rv2142A
uniprot id: P9WJ75
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin ParD2
up seq anno feature ids: PRO_0000408461

83332:Rv1980c
gene id: 83332:Rv1980c
uniprot id: P9WIN9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Immunogenic protein MPT64
up seq anno feature ids: PRO_0000021738

83332:Rv2804c
gene id: 83332:Rv2804c
uniprot id: I6YEE9
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Basic residues
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1442
gene id: 83332:Rv1442
uniprot id: O06817
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Molybdopterin dinucleotide-binding
up seq anno comments: Molybdopterin oxidoreductase
up seq anno comments: Molybdopterin oxidoreductase N-terminal

83332:Rv0048c
gene id: 83332:Rv0048c
uniprot id: P9WM87
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0048c
up seq anno feature ids: PRO_0000014065

83332:Rv1814
gene id: 83332:Rv1814
uniprot id: P9WNZ9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: C-5 sterol desaturase
up seq anno comments: Fatty acid hydroxylase
up seq anno comments: Helical
up seq anno feature ids: PRO_0000117041

83332:Rv2975c
gene id: 83332:Rv2975c
uniprot id: P95120
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DhaL

83332:Rv2631
gene id: 83332:Rv2631
uniprot id: P9WGW5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: GMP-histidine intermediate
up seq anno comments: RNA-splicing ligase RtcB
up seq anno feature ids: PRO_0000215111

83332:Rv1272c
gene id: 83332:Rv1272c
uniprot id: P9WQJ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Disordered
up seq anno comments: Fatty acid ABC transporter ATP-binding/permease protein
up seq anno comments: Helical
up seq anno feature ids: PRO_0000093261

83332:Rv3484
gene id: 83332:Rv3484
uniprot id: O06347
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Cell envelope-related transcriptional attenuator
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: LytR/CpsA/Psr regulator C-terminal
up seq anno comments: Polar residues

83332:Rv1040c
gene id: 83332:Rv1040c
uniprot id: L7N667
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PPE family C-terminal

83332:Rv3297
gene id: 83332:Rv3297
uniprot id: P9WNC1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Zinc Finger
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Zinc Finger
up seq anno comments: Endonuclease 8 2
up seq anno comments: FPG-type
up seq anno comments: Proton donor
up seq anno comments: Proton donor; for beta-elimination activity
up seq anno comments: Proton donor; for delta-elimination activity
up seq anno comments: Removed
up seq anno comments: Schiff-base intermediate with DNA
up seq anno feature ids: PRO_0000170901

83332:Rv2775
gene id: 83332:Rv2775
uniprot id: O33317
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase
up seq anno comments: Probable N-acetyltransferase Rv2775
up seq anno feature ids: PRO_0000457296

83332:Rv0172
gene id: 83332:Rv0172
uniprot id: O07416
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv2519
gene id: 83332:Rv2519
uniprot id: Q79FD3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv3092c
gene id: 83332:Rv3092c
uniprot id: I6Y2I9
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2206
gene id: 83332:Rv2206
uniprot id: P9WLI5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Uncharacterized protein Rv2206
up seq anno feature ids: PRO_0000103974

83332:Rv0761c
gene id: 83332:Rv0761c
uniprot id: P9WQC7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Alcohol dehydrogenase B
up seq anno feature ids: PRO_0000160743

83332:Rv3613c
gene id: 83332:Rv3613c
uniprot id: O06270
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0842
gene id: 83332:Rv0842
uniprot id: O53854
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile

83332:Rv0315
gene id: 83332:Rv0315
uniprot id: O07242
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: GH16
up seq anno feature ids: PRO_5010335828

83332:Rv3424c
gene id: 83332:Rv3424c
uniprot id: P9WKY3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3424c
up seq anno feature ids: PRO_0000104135

83332:Rv0664
gene id: 83332:Rv0664
uniprot id: O06775
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Putative antitoxin VapB8
up seq anno feature ids: PRO_0000408057

83332:Rv0136
gene id: 83332:Rv0136
uniprot id: P9WPM3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative cytochrome P450 138
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052298

83332:Rv1855c
gene id: 83332:Rv1855c
uniprot id: P95159
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Luciferase-like

83332:Rv1495
gene id: 83332:Rv1495
uniprot id: P9WII5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Endoribonuclease MazF4
up seq anno feature ids: PRO_0000201902

83332:Rv3576
gene id: 83332:Rv3576
uniprot id: I6YGJ4
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PknH-like extracellular
up seq anno feature ids: PRO_5038703585

83332:Rv3098A
gene id: 83332:Rv3098A
uniprot id: V5QRX7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative toxin Rv3098A/RVBD_3098A
up seq anno feature ids: PRO_0000431255

83332:Rv2325c
gene id: 83332:Rv2325c
uniprot id: P9WPI7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2325c
up seq anno feature ids: PRO_0000104028

83332:Rv1860
gene id: 83332:Rv1860
uniprot id: P9WIR7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Glycosylation Site
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Glycosylation Site
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1
up seq anno comments: 2
up seq anno comments: 3
up seq anno comments: 3 X 4 AA approximate repeats of [DA]-P-N-A
up seq anno comments: Alanine and proline-rich secreted protein Apa
up seq anno comments: Chemically or enzymatically deglycosylated protein.
up seq anno comments: Disordered
up seq anno comments: O-linked (Man) threonine
up seq anno comments: O-linked (Man...) threonine
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000020745

83332:Rv0962c
gene id: 83332:Rv0962c
uniprot id: P9WK39
up seq anno parent labels: Chain
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Signal Peptide
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: S-diacylglycerol cysteine
up seq anno comments: Uncharacterized lipoprotein LprP
up seq anno feature ids: PRO_0000018152

83332:Rv2154c
gene id: 83332:Rv2154c
uniprot id: P9WN97
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Probable peptidoglycan glycosyltransferase FtsW
up seq anno feature ids: PRO_0000062725

83332:Rv3331
gene id: 83332:Rv3331
uniprot id: L0TDU1
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile

83332:Rv0253
gene id: 83332:Rv0253
uniprot id: O53675
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rieske-like [2Fe-2S]

83332:Rv2473
gene id: 83332:Rv2473
uniprot id: O53200
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv2985
gene id: 83332:Rv2985
uniprot id: P9WIY3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: 8-oxo-(d)GTP phosphatase
up seq anno comments: Nudix box
up seq anno comments: Nudix hydrolase
up seq anno feature ids: PRO_0000391775

83332:Rv1970
gene id: 83332:Rv1970
uniprot id: O53971
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv2821c
gene id: 83332:Rv2821c
uniprot id: P9WJF9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: CRISPR system Cms endoribonuclease Csm3
up seq anno feature ids: PRO_0000418226

83332:Rv2292c
gene id: 83332:Rv2292c
uniprot id: P9WLE3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv2292c
up seq anno feature ids: PRO_0000014128

83332:Rv1796
gene id: 83332:Rv1796
uniprot id: O53945
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Charge relay system
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Mycosin-5
up seq anno comments: Peptidase S8
up seq anno comments: Pro residues
up seq anno feature ids: PRO_5007696963

83332:Rv0929
gene id: 83332:Rv0929
uniprot id: P9WG05
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Sequence Conflict
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Phosphate transport system permease protein PstC 2
up seq anno feature ids: PRO_0000060219

83332:Rv1747
gene id: 83332:Rv1747
uniprot id: O65934
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: ABC transmembrane type-2
up seq anno comments: ABC transporter
up seq anno comments: ABC transporter ATP-binding/permease protein Rv1747
up seq anno comments: Disordered
up seq anno comments: FHA 1
up seq anno comments: FHA 2
up seq anno comments: Helical
up seq anno comments: Lack of phosphorylation. Attenuates growth in macrophages and in mice; when associated with A-152.
up seq anno comments: Lack of phosphorylation. Attenuates growth in macrophages and in mice; when associated with A-210.
up seq anno comments: Loss of ATPase activity.
up seq anno comments: Phosphothreonine
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Strong decrease in phosphorylation.
up seq anno comments: Strong decrease in phosphorylation. Decreases interaction with PknF.
up seq anno comments: Strong decrease in phosphorylation. Lack of interaction with PknF. Attenuates growth in macrophages.
up seq anno feature ids: PRO_0000419321

83332:Rv1200
gene id: 83332:Rv1200
uniprot id: O05301
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile

83332:Rv2937
gene id: 83332:Rv2937
uniprot id: P9WG23
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-2
up seq anno comments: Doxorubicin resistance ABC transporter permease protein DrrB
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393226

83332:Rv0146
gene id: 83332:Rv0146
uniprot id: P9WFJ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0146
up seq anno feature ids: PRO_0000361236

83332:Rv0486
gene id: 83332:Rv0486
uniprot id: P9WMY7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: D-inositol 3-phosphate glycosyltransferase
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000080318

83332:Rv1331
gene id: 83332:Rv1331
uniprot id: P9WPC1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ATP-dependent Clp protease adapter protein ClpS
up seq anno feature ids: PRO_0000215726

83332:Rv3073c
gene id: 83332:Rv3073c
uniprot id: P9WL11
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv3073c
up seq anno feature ids: PRO_0000104112

83332:Rv3922c
gene id: 83332:Rv3922c
uniprot id: P9WFL9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Putative membrane protein insertion efficiency factor
up seq anno feature ids: PRO_0000171841

83332:Rv1167c
gene id: 83332:Rv1167c
uniprot id: O50423
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv1992c
gene id: 83332:Rv1992c
uniprot id: P9WPS7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Disordered
up seq anno comments: HMA
up seq anno comments: Helical
up seq anno comments: Probable cation-transporting ATPase G
up seq anno feature ids: PRO_0000046345

83332:Rv3682
gene id: 83332:Rv3682
uniprot id: I6YGX2
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PASTA
up seq anno comments: Pro residues

83332:Rv3346c
gene id: 83332:Rv3346c
uniprot id: O50377
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0060
gene id: 83332:Rv0060
uniprot id: O53605
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: DNA ADP-ribosyl glycohydrolase
up seq anno comments: Macro
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000456046

83332:Rv1454c
gene id: 83332:Rv1454c
uniprot id: O53146
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Enoyl reductase (ER)

83332:Rv1825
gene id: 83332:Rv1825
uniprot id: P9WFG3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: UPF0749 protein Rv1825
up seq anno feature ids: PRO_0000014112

83332:Rv1282c
gene id: 83332:Rv1282c
uniprot id: P9WFZ9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical
up seq anno comments: Putative peptide transport permease protein Rv1282c
up seq anno feature ids: PRO_0000060289

83332:Rv1135c
gene id: 83332:Rv1135c
uniprot id: P9WI29
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Uncharacterized PPE family protein PPE16
up seq anno feature ids: PRO_0000379587

83332:Rv2112c
gene id: 83332:Rv2112c
uniprot id: P9WNU9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno comments: Abolishes pupylation and depupylase activity.
up seq anno comments: Abolishes pupylation.
up seq anno comments: Proton acceptor
up seq anno comments: Pup deamidase/depupylase
up seq anno feature ids: PRO_0000383480

83332:Rv3309c
gene id: 83332:Rv3309c
uniprot id: P9WFF3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Uracil phosphoribosyltransferase
up seq anno feature ids: PRO_0000120858

83332:Rv0182c
gene id: 83332:Rv0182c
uniprot id: P9WGG5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Motif
up seq anno labels: Region
up seq anno comments: ECF RNA polymerase sigma factor SigG
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000423098

83332:Rv1939
gene id: 83332:Rv1939
uniprot id: P95275
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Flavin reductase like

83332:Rv3103c
gene id: 83332:Rv3103c
uniprot id: O05780
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Pro residues

83332:Rv2780
gene id: 83332:Rv2780
uniprot id: P9WQB1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alanine dehydrogenase
up seq anno comments: Completely inactive mutant.
up seq anno comments: Completely inactive mutant. The bifurcated hydrogen bond between D-270 and the ribose of NAD is replaced by a single hydrogen bond.
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000198994

83332:Rv0363c
gene id: 83332:Rv0363c
uniprot id: P9WQA3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Fructose-bisphosphate aldolase
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000178722

83332:Rv0007
gene id: 83332:Rv0007
uniprot id: P9WMA7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0007
up seq anno feature ids: PRO_0000103637

83332:Rv0872c
gene id: 83332:Rv0872c
uniprot id: Q79FV3
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv3625c
gene id: 83332:Rv3625c
uniprot id: P9WG53
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: tRNA(Ile)-lysidine synthase
up seq anno feature ids: PRO_0000181725

83332:Rv0326
gene id: 83332:Rv0326
uniprot id: O07251
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv3799c
gene id: 83332:Rv3799c
uniprot id: O53578
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Biotin-dependent long chain acyl-coenzyme A carboxylase beta4 subunit
up seq anno comments: CoA carboxyltransferase C-terminal
up seq anno comments: CoA carboxyltransferase N-terminal
up seq anno feature ids: PRO_0000452370

83332:Rv0674
gene id: 83332:Rv0674
uniprot id: I6WZ26
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: PaaX domain-containing protein, C-domain protein
up seq anno comments: PaaX-like C-terminal
up seq anno comments: PaaX-like N-terminal
up seq anno feature ids: PRO_5010234064

83332:Rv3629c
gene id: 83332:Rv3629c
uniprot id: O06378
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3652
gene id: 83332:Rv3652
uniprot id: Q6MWV1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS60
up seq anno feature ids: PRO_0000438130

83332:Rv1512
gene id: 83332:Rv1512
uniprot id: P71791
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: Important for catalytic activity
up seq anno comments: NAD-dependent epimerase/dehydratase
up seq anno comments: Proton donor/acceptor

83332:Rv0972c
gene id: 83332:Rv0972c
uniprot id: P9WQG3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Acyl-CoA dehydrogenase FadE12
up seq anno feature ids: PRO_0000201185

83332:Rv1335
gene id: 83332:Rv1335
uniprot id: P9WP33
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1-thioglycine; alternate
up seq anno comments: CysO-cysteine adduct.
up seq anno comments: CysO-cysteine adduct; alternate
up seq anno comments: Native form.
up seq anno comments: Sulfur carrier protein CysO
up seq anno comments: Thiocarboxylated form.
up seq anno feature ids: PRO_0000159082

83332:Rv2520c
gene id: 83332:Rv2520c
uniprot id: I6XEI0
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1302
gene id: 83332:Rv1302
uniprot id: P9WMW5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Site
up seq anno labels: Transmembrane
up seq anno comments: Could be required for catalysis
up seq anno comments: Decaprenyl-phosphate N-acetylglucosaminephosphotransferase
up seq anno comments: Helical
up seq anno comments: Important in orienting the substrate
up seq anno comments: Important in orienting the substrate; probably interacts with magnesium or manganese
up seq anno feature ids: PRO_0000108951

83332:Rv2166c
gene id: 83332:Rv2166c
uniprot id: P9WJN9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: SpoVT-AbrB 1
up seq anno comments: SpoVT-AbrB 2
up seq anno comments: Transcriptional regulator MraZ
up seq anno feature ids: PRO_0000108510

83332:Rv0797
gene id: 83332:Rv0797
uniprot id: O07182
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Transposase IS110-like N-terminal
up seq anno comments: Transposase IS116/IS110/IS902 C-terminal

83332:Rv0267
gene id: 83332:Rv0267
uniprot id: P95224
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2485c
gene id: 83332:Rv2485c
uniprot id: I6Y9F7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Esterase LipQ
up seq anno feature ids: PRO_0000448881

83332:Rv2302
gene id: 83332:Rv2302
uniprot id: P9WLD5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Uncharacterized protein Rv2302
up seq anno feature ids: PRO_0000104011

83332:Rv0942
gene id: 83332:Rv0942
uniprot id: P9WKN9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0942
up seq anno feature ids: PRO_0000103745

83332:Rv0456B
gene id: 83332:Rv0456B
uniprot id: P0CL57
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable antitoxin MazE1
up seq anno feature ids: PRO_0000406295

83332:Rv3120
gene id: 83332:Rv3120
uniprot id: O05796
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv0373c
gene id: 83332:Rv0373c
uniprot id: O53708
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
up seq anno comments: Disordered

83332:Rv3498c
gene id: 83332:Rv3498c
uniprot id: I6X7G8
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD

83332:Rv2947c
gene id: 83332:Rv2947c
uniprot id: P96284
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Putative inactive phenolphthiocerol synthesis polyketide synthase type I Pks15
up seq anno feature ids: PRO_0000406363

83332:Rv0158
gene id: 83332:Rv0158
uniprot id: O53641
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3084
gene id: 83332:Rv3084
uniprot id: P9WK85
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Signal Peptide
up seq anno comments: Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole
up seq anno comments: Putative acetyl-hydrolase LipR
up seq anno feature ids: PRO_0000420877

83332:Rv1866
gene id: 83332:Rv1866
uniprot id: P95149
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: Probable CoA-transferase Rv1866
up seq anno feature ids: PRO_0000432516

83332:Rv0492c
gene id: 83332:Rv0492c
uniprot id: P9WMV7
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized GMC-type oxidoreductase Rv0492c
up seq anno feature ids: PRO_0000205615

83332:Rv2530c
gene id: 83332:Rv2530c
uniprot id: P9WF63
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC39
up seq anno feature ids: PRO_0000407894

83332:Rv3812
gene id: 83332:Rv3812
uniprot id: L7N680
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS62
up seq anno feature ids: PRO_0000451249

83332:Rv2002
gene id: 83332:Rv2002
uniprot id: P9WGT1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
up seq anno comments: Complete loss of both oxidation of androsterone and reduction of progesterone; when associated with T6; M-47 and K-69.
up seq anno comments: Maximal improvement in solubility; when associated with M-47 and K-69.
up seq anno comments: Maximal improvement in solubility; when associated with T-6 and K-69.
up seq anno comments: Maximal improvement in solubility; when associated with T-6 and M-47.
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000054712

83332:Rv0635
gene id: 83332:Rv0635
uniprot id: P9WFK1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: UPF0336 protein Rv0635
up seq anno feature ids: PRO_0000216143

83332:Rv3768
gene id: 83332:Rv3768
uniprot id: P72035
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: SnoaL-like

83332:Rv1500
gene id: 83332:Rv1500
uniprot id: P9WMX5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Putative glycosyltransferases
up seq anno feature ids: PRO_0000393107

83332:Rv0281
gene id: 83332:Rv0281
uniprot id: P9WFI9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0281
up seq anno feature ids: PRO_0000361239

83332:Rv1464
gene id: 83332:Rv1464
uniprot id: P9WQ69
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: N-acetylthreonine
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable cysteine desulfurase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000150304

83332:Rv1835c
gene id: 83332:Rv1835c
uniprot id: P9WIQ9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Charge relay system
up seq anno comments: Putative serine esterase Rv1835c
up seq anno feature ids: PRO_0000103908

83332:Rv0460
gene id: 83332:Rv0460
uniprot id: O53745
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1292
gene id: 83332:Rv1292
uniprot id: P9WFW5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: 'HIGH' region
up seq anno comments: Arginine--tRNA ligase
up seq anno feature ids: PRO_0000151580

83332:Rv2124c
gene id: 83332:Rv2124c
uniprot id: O33259
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: AdoMet activation
up seq anno comments: B12-binding
up seq anno comments: B12-binding N-terminal
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Hcy-binding
up seq anno comments: Methionine synthase
up seq anno comments: Pterin-binding
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000204534

83332:Rv0192
gene id: 83332:Rv0192
uniprot id: O07436
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Basic and acidic residues
up seq anno comments: Binds to carbapenem drug (covalent)
up seq anno comments: Disordered
up seq anno comments: L,D-TPase catalytic
up seq anno comments: L,D-transpeptidase 4
up seq anno comments: Nucleophile
up seq anno comments: Pro residues
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000430336

83332:Rv2477c
gene id: 83332:Rv2477c
uniprot id: P9WQK3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: ABC transporter 1
up seq anno comments: ABC transporter 2
up seq anno comments: Arm
up seq anno comments: Energy-dependent translational throttle protein EttA
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: PtIM
up seq anno feature ids: PRO_0000395861

83332:Rv2790c
gene id: 83332:Rv2790c
uniprot id: O33332
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thiolase C-terminal
up seq anno comments: Thiolase N-terminal

83332:Rv3673c
gene id: 83332:Rv3673c
uniprot id: I6YGW6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Thioredoxin

83332:Rv2442c
gene id: 83332:Rv2442c
uniprot id: P9WHC3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Large ribosomal subunit protein bL21
up seq anno feature ids: PRO_0000181010

83332:Rv0018c
gene id: 83332:Rv0018c
uniprot id: P9WHW5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 60% loss of phosphatase activity.
up seq anno comments: 90% loss of phosphatase activity.
up seq anno comments: Cytoplasmic
up seq anno comments: Decreases affinity for Mn3 by 4-fold, no effect on hydrolysis of p-nitrophenyl phosphate.
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: No change in activity.
up seq anno comments: No change in affinity for Mn3, no effect on hydrolysis of p-nitrophenyl phosphate.
up seq anno comments: PPM-type phosphatase
up seq anno comments: Phosphothreonine; by PknA and PknB
up seq anno comments: Phosphothreonine; by PknB
up seq anno comments: Polar residues
up seq anno comments: Pro residues
up seq anno comments: Serine/threonine protein phosphatase PstP
up seq anno feature ids: PRO_0000344805

83332:Rv3635
gene id: 83332:Rv3635
uniprot id: I6Y460
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0864
gene id: 83332:Rv0864
uniprot id: P9WJR7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cyclic pyranopterin monophosphate synthase 2
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000097812

83332:Rv3448
gene id: 83332:Rv3448
uniprot id: P9WNQ1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: ESX-4 secretion system protein eccD4
up seq anno comments: Helical
up seq anno feature ids: PRO_0000393236

83332:Rv0686
gene id: 83332:Rv0686
uniprot id: I6XVZ6
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0928
gene id: 83332:Rv0928
uniprot id: P9WGT7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Sequence Variant
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno comments: In strain: Erdman.
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Phosphate-binding protein PstS 3
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000031859

83332:Rv3784
gene id: 83332:Rv3784
uniprot id: P72050
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD(P)-binding

83332:Rv1522c
gene id: 83332:Rv1522c
uniprot id: P9WJT7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable transport protein MmpL12
up seq anno feature ids: PRO_0000103580

83332:Rv1180
gene id: 83332:Rv1180
uniprot id: A0A089QRB9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Lipid Binding
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Acyl-ester intermediate; for acyltransferase activity
up seq anno comments: Acyl-thioester intermediate; for beta-ketoacyl synthase activity
up seq anno comments: Acyltransferase (AT)
up seq anno comments: Beta-ketoacyl reductase (KR)
up seq anno comments: C-terminal hotdog fold
up seq anno comments: Carrier
up seq anno comments: Dehydratase (DH)
up seq anno comments: Enoylreductase (ER)
up seq anno comments: For beta-ketoacyl synthase activity
up seq anno comments: Ketosynthase family 3 (KS3)
up seq anno comments: Linker domain (LD)
up seq anno comments: Mycolipanoate synthase
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: N-terminal hotdog fold
up seq anno comments: O-(pantetheine 4'-phosphoryl)serine
up seq anno comments: PKS/mFAS DH
up seq anno comments: Proton acceptor; for dehydratase activity
up seq anno comments: Proton donor; for dehydratase activity
up seq anno comments: Pseudo beta-ketoacyl reductase (PsiKR)
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000438278

83332:Rv0985c
gene id: 83332:Rv0985c
uniprot id: P9WJN5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Large-conductance mechanosensitive channel
up seq anno feature ids: PRO_0000192452

83332:Rv1346
gene id: 83332:Rv1346
uniprot id: P9WQF9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-[acyl-carrier-protein] dehydrogenase MbtN
up seq anno feature ids: PRO_0000000538

83332:Rv2178c
gene id: 83332:Rv2178c
uniprot id: O53512
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Phospho-2-dehydro-3-deoxyheptonate aldolase AroG
up seq anno feature ids: PRO_0000414909

83332:Rv0807
gene id: 83332:Rv0807
uniprot id: I6Y8U3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Bacterial SCP orthologue

83332:Rv1638
gene id: 83332:Rv1638
uniprot id: P9WQK7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno parent labels: Zinc Finger
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno labels: Zinc Finger
up seq anno comments: ABC transporter 1
up seq anno comments: ABC transporter 2
up seq anno comments: C4-type
up seq anno comments: C4-type; atypical
up seq anno comments: UvrABC system protein A
up seq anno feature ids: PRO_0000093070

83332:Rv2841c
gene id: 83332:Rv2841c
uniprot id: P9WIV3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: KH 1
up seq anno comments: KH 2
up seq anno comments: S1 motif
up seq anno comments: Transcription termination/antitermination protein NusA
up seq anno feature ids: PRO_0000181974

83332:Rv1469
gene id: 83332:Rv1469
uniprot id: P9WPT3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: 4-aspartylphosphate intermediate
up seq anno comments: Helical
up seq anno comments: Probable cobalt/nickel-exporting P-type ATPase
up seq anno feature ids: PRO_0000046339

83332:Rv3694c
gene id: 83332:Rv3694c
uniprot id: O69662
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2308
gene id: 83332:Rv2308
uniprot id: P9WLC5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2308
up seq anno feature ids: PRO_0000104017

83332:Rv3133c
gene id: 83332:Rv3133c
uniprot id: P9WMF9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Able to bind DNA, no longer induces hypoxic response.
up seq anno comments: DNA-binding transcriptional activator DevR/DosR
up seq anno comments: Decreases phosphorylation by PknH.
up seq anno comments: H-T-H motif
up seq anno comments: HTH luxR-type
up seq anno comments: No longer induces expression of DevR regulon under hypoxic conditions, phosphorylated slowly and incompletely by DevS, decreased cooperative binding of target DNA.
up seq anno comments: No phosphorylation by DevS (DosS) nor by DosT.
up seq anno comments: No phosphorylation by DevS (DosS).
up seq anno comments: No phosphorylation by PknH.
up seq anno comments: Phosphothreonine; by PknH
up seq anno comments: Response regulatory
up seq anno feature ids: PRO_0000392625

83332:Rv0385
gene id: 83332:Rv0385
uniprot id: Q7ARS9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding FR-type

83332:Rv3513c
gene id: 83332:Rv3513c
uniprot id: I6YGC8
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv1609
gene id: 83332:Rv1609
uniprot id: P9WFX3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Anthranilate synthase component 1
up seq anno feature ids: PRO_0000154099

83332:Rv3314c
gene id: 83332:Rv3314c
uniprot id: P9WFS1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Thymidine phosphorylase
up seq anno feature ids: PRO_0000059082

83332:Rv2957
gene id: 83332:Rv2957
uniprot id: P9WMX7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: PGL/p-HBAD biosynthesis glycosyltransferase Rv2957
up seq anno feature ids: PRO_0000059251

83332:Rv3810
gene id: 83332:Rv3810
uniprot id: P9WIQ7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Repeat
up seq anno labels: Sequence Conflict
up seq anno labels: Sequence Variant
up seq anno labels: Signal Peptide
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: 1-1
up seq anno comments: 1-2
up seq anno comments: 1-3
up seq anno comments: 1-4
up seq anno comments: 1-5
up seq anno comments: 1-6
up seq anno comments: 2-1
up seq anno comments: 2-2
up seq anno comments: 2-3
up seq anno comments: 2-4
up seq anno comments: 2-5
up seq anno comments: 2-6
up seq anno comments: 6 X 5 AA approximate tandem repeats of P-[ATG]-[LG]-X-X
up seq anno comments: 6 X 5 AA tandem repeats of P-[GA]-L-T-S
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Exported repetitive protein
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: In strain: MT103.
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000021201

83332:Rv3094c
gene id: 83332:Rv3094c
uniprot id: O05773
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal

83332:Rv1876
gene id: 83332:Rv1876
uniprot id: P9WPQ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno comments: Bacterioferritin BfrA
up seq anno comments: Ferritin-like diiron
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000192600

83332:Rv1007c
gene id: 83332:Rv1007c
uniprot id: P9WFU5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 'HIGH' region
up seq anno comments: 'KMSKS' region
up seq anno comments: Disordered
up seq anno comments: Methionine--tRNA ligase
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000139233

83332:Rv0502
gene id: 83332:Rv0502
uniprot id: P9WKT1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0502
up seq anno feature ids: PRO_0000103709

83332:Rv3641c
gene id: 83332:Rv3641c
uniprot id: I6YCN3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Fido

83332:Rv0830
gene id: 83332:Rv0830
uniprot id: P9WFI3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0830
up seq anno feature ids: PRO_0000361244

83332:Rv2015c
gene id: 83332:Rv2015c
uniprot id: O53461
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: HNH nuclease

83332:Rv2541
gene id: 83332:Rv2541
uniprot id: P95012
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0330c
gene id: 83332:Rv0330c
uniprot id: O07254
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv0646c
gene id: 83332:Rv0646c
uniprot id: P96935
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv3778c
gene id: 83332:Rv3778c
uniprot id: P9WQ67
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Uncharacterized protein Rv3778c
up seq anno feature ids: PRO_0000415516

83332:Rv0293c
gene id: 83332:Rv0293c
uniprot id: O53697
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1

83332:Rv1847
gene id: 83332:Rv1847
uniprot id: P9WIM3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Putative esterase Rv1847
up seq anno feature ids: PRO_0000156683

83332:Rv0473
gene id: 83332:Rv0473
uniprot id: I6Y3V3
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1307
gene id: 83332:Rv1307
uniprot id: P9WPV3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: ATP synthase subunit b
up seq anno comments: ATP synthase subunit b-delta
up seq anno comments: ATP synthase subunit delta
up seq anno comments: Helical
up seq anno feature ids: PRO_0000193473

83332:Rv0954
gene id: 83332:Rv0954
uniprot id: P9WIR9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: 34 kDa antigenic protein homolog
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Polar residues
up seq anno comments: Removed
up seq anno feature ids: PRO_0000064364

83332:Rv2659c
gene id: 83332:Rv2659c
uniprot id: P9WMB3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Core-binding (CB)
up seq anno comments: O-(3'-phospho-DNA)-tyrosine intermediate
up seq anno comments: Putative prophage phiRv2 integrase
up seq anno comments: Tyr recombinase
up seq anno feature ids: PRO_0000392940

83332:Rv2136c
gene id: 83332:Rv2136c
uniprot id: P9WFF9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Undecaprenyl-diphosphatase
up seq anno feature ids: PRO_0000151166

83332:Rv2977c
gene id: 83332:Rv2977c
uniprot id: P9WG71
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Thiamine-monophosphate kinase
up seq anno feature ids: PRO_0000415641

83332:Rv1961
gene id: 83332:Rv1961
uniprot id: P95253
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv2800
gene id: 83332:Rv2800
uniprot id: I6YEE6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Xaa-Pro dipeptidyl-peptidase C-terminal

83332:Rv3684
gene id: 83332:Rv3684
uniprot id: O69652
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: L-cysteine desulfhydrase Cds1
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000456520

83332:Rv0875c
gene id: 83332:Rv0875c
uniprot id: P9WKR7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv0875c
up seq anno feature ids: PRO_0000014079

83332:Rv2628
gene id: 83332:Rv2628
uniprot id: P9WL65
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative uncharacterized protein Rv2628
up seq anno feature ids: PRO_0000393358

83332:Rv1000c
gene id: 83332:Rv1000c
uniprot id: L7N6A4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Fe2OG dioxygenase

83332:Rv3465
gene id: 83332:Rv3465
uniprot id: P9WH11
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno comments: dTDP-4-dehydrorhamnose 3,5-epimerase
up seq anno feature ids: PRO_0000395349

83332:Rv1532c
gene id: 83332:Rv1532c
uniprot id: O06178
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Thioesterase

83332:Rv0168
gene id: 83332:Rv0168
uniprot id: L0T2Q9
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3282
gene id: 83332:Rv3282
uniprot id: P9WK27
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Nucleoside triphosphate pyrophosphatase
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000123030

83332:Rv0996
gene id: 83332:Rv0996
uniprot id: O05579
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1356c
gene id: 83332:Rv1356c
uniprot id: P9WM09
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1356c
up seq anno feature ids: PRO_0000103826

83332:Rv2747
gene id: 83332:Rv2747
uniprot id: O33289
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Amino-acid acetyltransferase
up seq anno comments: N-acetyltransferase
up seq anno feature ids: PRO_0000420585

83332:Rv0818
gene id: 83332:Rv0818
uniprot id: O53830
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: OmpR/PhoB-type

83332:Rv1649
gene id: 83332:Rv1649
uniprot id: P9WFU3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Phenylalanine--tRNA ligase alpha subunit
up seq anno feature ids: PRO_0000126733

83332:Rv2231A
gene id: 83332:Rv2231A
uniprot id: P0CV93
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Ribonuclease VapC16
up seq anno feature ids: PRO_0000407875

83332:Rv1481
gene id: 83332:Rv1481
uniprot id: P9WFJ7
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0353 protein Rv1481
up seq anno comments: VWFA
up seq anno feature ids: PRO_0000057648

83332:Rv3704c
gene id: 83332:Rv3704c
uniprot id: P9WPK7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Glutamate--cysteine ligase EgtA
up seq anno feature ids: PRO_0000413646

83332:Rv2320c
gene id: 83332:Rv2320c
uniprot id: P71892
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1818c
gene id: 83332:Rv1818c
uniprot id: P9WIF5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Essential for translocation to the cell surface
up seq anno comments: Interacts with TLR2
up seq anno comments: PE
up seq anno comments: PE-PGRS family protein PE_PGRS33
up seq anno feature ids: PRO_0000216164

83332:Rv1972
gene id: 83332:Rv1972
uniprot id: O53973
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3146
gene id: 83332:Rv3146
uniprot id: P9WJH1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: NADH-quinone oxidoreductase subunit B
up seq anno feature ids: PRO_0000118773

83332:Rv0397
gene id: 83332:Rv0397
uniprot id: P95205
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv2151c
gene id: 83332:Rv2151c
uniprot id: P9WNA1
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cell division protein FtsQ
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: POTRA
up seq anno comments: Removed
up seq anno feature ids: PRO_0000160582

83332:Rv1619
gene id: 83332:Rv1619
uniprot id: O06136
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Helical
up seq anno comments: MprF-like
up seq anno comments: MprF-like domain protein Rv1619
up seq anno comments: Periplasmic
up seq anno feature ids: PRO_0000456585

83332:Rv2967c
gene id: 83332:Rv2967c
uniprot id: I6YEU0
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: ATP-grasp
up seq anno comments: Biotin carboxylation
up seq anno comments: Lipoyl-binding
up seq anno comments: N6-biotinyllysine
up seq anno comments: N6-carboxylysine
up seq anno comments: Pyruvate carboxyltransferase
up seq anno comments: via carbamate group

83332:Rv3823c
gene id: 83332:Rv3823c
uniprot id: P9WJU5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Sulfolipid-1 exporter MmpL8
up seq anno feature ids: PRO_0000103572

83332:Rv1058
gene id: 83332:Rv1058
uniprot id: O53406
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-binding enzyme C-terminal
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv0696
gene id: 83332:Rv0696
uniprot id: P9WMX1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Pre-mycofactocin glycosyltransferase
up seq anno feature ids: PRO_0000415278

83332:Rv1886c
gene id: 83332:Rv1886c
uniprot id: P9WQP1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Diacylglycerol acyltransferase/mycolyltransferase Ag85B
up seq anno comments: Fibronectin-binding
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000000222

83332:Rv0514
gene id: 83332:Rv0514
uniprot id: O33359
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2551c
gene id: 83332:Rv2551c
uniprot id: I6Y9M6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Prepilin type IV endopeptidase peptidase

83332:Rv0341
gene id: 83332:Rv0341
uniprot id: P9WJ97
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Isoniazid-induced protein IniB
up seq anno feature ids: PRO_0000390792

83332:Rv0657c
gene id: 83332:Rv0657c
uniprot id: P9WJ57
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB6
up seq anno feature ids: PRO_0000408054

83332:Rv3790
gene id: 83332:Rv3790
uniprot id: P9WJF1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Confers resistance to BTZ043 and PBTZ169. Decreases M.tuberculosis cytotoxicity in macrophages. Does not affect binding affinity of the substrate to the enzyme, and only slightly affects catalytic efficiency. Is only partially inhibited by PBTZ169 at high concentrations, while totally inhibited by the non-covalent inhibitor Ty38c.
up seq anno comments: Confers resistance to BTZ043 and PBTZ169. Decreases M.tuberculosis cytotoxicity in macrophages. Does not affect binding affinity of the substrate to the enzyme, but reduces catalytic efficiency by 4-fold. Is only partially inhibited by PBTZ169 at high concentrations, while totally inhibited by the non-covalent inhibitor Ty38c.
up seq anno comments: Confers resistance to BTZ043 and PBTZ169. Loss of covalent modification with BTZ043. Decreases M.tuberculosis cytotoxicity in macrophages. Does not affect binding affinity of the substrate to the enzyme, but reduces catalytic efficiency by 4-fold. Is only partially inhibited by PBTZ169 at high concentrations, while nearly totally inhibited by the non-covalent inhibitor Ty38c.
up seq anno comments: Decaprenylphosphoryl-beta-D-ribose oxidase
up seq anno comments: FAD-binding PCMH-type
up seq anno comments: In a spontaneous TCA1-resistant mutant strain, but sensitive to BTZ.
up seq anno comments: In strain: NTB1; BTZ043-resistant.
up seq anno comments: In strain: NTB9; BTZ043-resistant.
up seq anno comments: In strain: TRC11; Ty38c-resistant mutant strain lacking Rv3406, but sensitive to moxifloxacin.
up seq anno comments: In strain: TRC12; Ty38c-resistant mutant strain lacking Rv3406, but sensitive to moxifloxacin.
up seq anno comments: Significantly less susceptible to Ty38c inhibition. 34-fold reduction in catalytic activity.
up seq anno comments: Significantly less susceptible to Ty38c inhibition. 7-fold reduction in catalytic activity.
up seq anno feature ids: PRO_0000390891

83332:Rv1185c
gene id: 83332:Rv1185c
uniprot id: P9WQ49
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Putative fatty-acid--CoA ligase FadD21
up seq anno feature ids: PRO_0000193136

83332:Rv3204
gene id: 83332:Rv3204
uniprot id: O05862
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding

83332:Rv2183c
gene id: 83332:Rv2183c
uniprot id: O53517
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Polar residues

83332:Rv1317c
gene id: 83332:Rv1317c
uniprot id: P9WJW3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: DNA-3-methyladenine glycosylase
up seq anno comments: Determinant for substrate specificity and/or DNA glycosylase activity
up seq anno comments: H-T-H motif
up seq anno comments: HTH araC/xylS-type
up seq anno comments: Methylphosphotriester-DNA--protein-cysteine methyltransferase
up seq anno comments: Nucleophile; methyl group acceptor from methylphosphotriester
up seq anno comments: Probable bifunctional transcriptional activator/DNA repair enzyme AlkA
up seq anno comments: Proton acceptor; for DNA glycosylase activity
up seq anno feature ids: PRO_0000139389

83332:Rv0964c
gene id: 83332:Rv0964c
uniprot id: P9WKM5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0964c
up seq anno feature ids: PRO_0000103762

83332:Rv2671
gene id: 83332:Rv2671
uniprot id: P71968
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: Bacterial bifunctional deaminase-reductase C-terminal

83332:Rv2147c
gene id: 83332:Rv2147c
uniprot id: P9WGJ5
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Cell division protein SepF
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000334047

83332:Rv2501c
gene id: 83332:Rv2501c
uniprot id: P9WPQ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno comments: ATP-grasp
up seq anno comments: Biotin carboxylation
up seq anno comments: Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit
up seq anno comments: Biotinyl-binding
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N6-biotinyllysine
up seq anno feature ids: PRO_0000146798

83332:Rv1630
gene id: 83332:Rv1630
uniprot id: P9WH43
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 2.5-fold decrease in binding of POA, decreased binding of tmRNA (expressed as residues 285-481).
up seq anno comments: 2.7-fold decrease in binding of POA, decreased binding of tmRNA (expressed as residues 285-481).
up seq anno comments: 3-fold decrease in binding of POA, decreased binding of tmRNA (expressed as residues 285-481).
up seq anno comments: Complete loss of POA binding, significantly decreased binding of tmRNA (expressed as residues 285-481).
up seq anno comments: Disordered
up seq anno comments: Does not bind POA. Binds tmRNA less strongly than wild-type, binding is not disrupted by POA.
up seq anno comments: Polar residues
up seq anno comments: S1 motif 1
up seq anno comments: S1 motif 2
up seq anno comments: S1 motif 3
up seq anno comments: S1 motif 4
up seq anno comments: Small ribosomal subunit protein bS1
up seq anno feature ids: PRO_0000196042

83332:Rv0603
gene id: 83332:Rv0603
uniprot id: O07775
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5010314127

83332:Rv2812
gene id: 83332:Rv2812
uniprot id: P71639
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Integrase catalytic

83332:Rv3328c
gene id: 83332:Rv3328c
uniprot id: L0TCG5
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Helix
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: ECF RNA polymerase sigma factor SigJ
up seq anno comments: H-T-H motif
up seq anno comments: Polymerase core binding
up seq anno comments: Sigma-70 factor domain-2
up seq anno comments: Sigma-70 factor domain-4
up seq anno feature ids: PRO_0000423648

83332:Rv2639c
gene id: 83332:Rv2639c
uniprot id: P9WFN9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: UPF0060 membrane protein Rv2639c
up seq anno feature ids: PRO_0000162333

83332:Rv3097c
gene id: 83332:Rv3097c
uniprot id: I6Y2J4
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Region
up seq anno labels: Site
up seq anno comments: Cleavage
up seq anno comments: Cytosolic triacylglycerol lipase
up seq anno comments: Extracellular triacylglycerol lipase
up seq anno comments: Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole
up seq anno comments: Linker
up seq anno comments: Lipase
up seq anno comments: PE
up seq anno feature ids: PRO_0000438268
up seq anno feature ids: PRO_0000449879

83332:Rv0034
gene id: 83332:Rv0034
uniprot id: P9WM93
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0034
up seq anno feature ids: PRO_0000103650

83332:Rv1093
gene id: 83332:Rv1093
uniprot id: P9WGI9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Plays an important role in substrate specificity
up seq anno comments: Serine hydroxymethyltransferase 1
up seq anno feature ids: PRO_0000113618

83332:Rv3150
gene id: 83332:Rv3150
uniprot id: P9WIV7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: NADH-quinone oxidoreductase subunit F
up seq anno feature ids: PRO_0000118574

83332:Rv3481c
gene id: 83332:Rv3481c
uniprot id: I6XHC3
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3105c
gene id: 83332:Rv3105c
uniprot id: P9WHG1
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N5-methylglutamine
up seq anno comments: Peptide chain release factor 2
up seq anno feature ids: PRO_0000166832

83332:Rv1542c
gene id: 83332:Rv1542c
uniprot id: P9WN25
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Turn
up seq anno comments: Group 1 truncated hemoglobin GlbN
up seq anno comments: proximal binding residue
up seq anno feature ids: PRO_0000162640

83332:Rv0179c
gene id: 83332:Rv0179c
uniprot id: O07423
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: Phosphodiester glycosidase
up seq anno feature ids: PRO_5039284231

83332:Rv3292
gene id: 83332:Rv3292
uniprot id: P9WL01
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: 2-oxoadipate dioxygenase/decarboxylase
up seq anno comments: Important for substrate specificity
up seq anno feature ids: PRO_0000104114

83332:Rv3801c
gene id: 83332:Rv3801c
uniprot id: O53580
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cannot be phosphorylated. No change in activity.
up seq anno comments: Catalyzes the formation of acyl-CoA; when associated with A-383.
up seq anno comments: Catalyzes the formation of acyl-CoA; when associated with A-481.
up seq anno comments: Confers resistance to the coumarin inhibitors.
up seq anno comments: Long-chain-fatty-acid--AMP ligase FadD32
up seq anno comments: Phosphomimetic mutant. 55% decrease in activity.
up seq anno comments: Phosphothreonine
up seq anno feature ids: PRO_0000406634

83332:Rv1368
gene id: 83332:Rv1368
uniprot id: P9WK47
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Mass
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Lipid Binding
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno comments: Disordered
up seq anno comments: Expressed in M.bovis, lipidated and glycosylated.
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: No longer increases KdpD induction at 0 and 250 uMK(+); when associated with S-185 and V-197.
up seq anno comments: No longer increases KdpD induction at 0 and 250 uMK(+); when associated with T-132 and S-185.
up seq anno comments: No longer increases KdpD induction at 0 and 250 uMK(+); when associated with T-132 and V-197.
up seq anno comments: Putative diacylated glycolipid transporter LprF
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000018143

83332:Rv2758c
gene id: 83332:Rv2758c
uniprot id: P9WJ43
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Antitoxin VapB21
up seq anno feature ids: PRO_0000408067

83332:Rv0004
gene id: 83332:Rv0004
uniprot id: P9WFL1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Sequence Conflict
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: UPF0232 protein Rv0004
up seq anno feature ids: PRO_0000211365

83332:Rv2386c
gene id: 83332:Rv2386c
uniprot id: P9WFX1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Could activate a water molecule for attack at the C2 of chorismate and involved in recognition/elimination of the C4 hydroxyl
up seq anno comments: No activity is observed.
up seq anno comments: Only the chorismate mutase activity is observed.
up seq anno comments: Proton donor
up seq anno comments: Salicylate synthase
up seq anno feature ids: PRO_0000262086

83332:Rv0483
gene id: 83332:Rv0483
uniprot id: P9WKV3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: L,D-TPase catalytic
up seq anno comments: L,D-transpeptidase 5
up seq anno comments: Nucleophile
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000430359

83332:Rv2193
gene id: 83332:Rv2193
uniprot id: P9WP67
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Helical
up seq anno comments: N-acetylthreonine
up seq anno comments: Probable cytochrome c oxidase subunit 3
up seq anno comments: Removed
up seq anno feature ids: PRO_0000183884

83332:Rv0634B
gene id: 83332:Rv0634B
uniprot id: P9WH95
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL33B
up seq anno feature ids: PRO_0000170195

83332:Rv1660
gene id: 83332:Rv1660
uniprot id: P9WPF5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno comments: Polyketide synthase-like Pks10
up seq anno feature ids: PRO_0000406360

83332:Rv2522c
gene id: 83332:Rv2522c
uniprot id: I6X4J0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Peptidase M20 dimerisation

83332:Rv1492
gene id: 83332:Rv1492
uniprot id: P9WJK7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable methylmalonyl-CoA mutase small subunit
up seq anno feature ids: PRO_0000194265

83332:Rv2333c
gene id: 83332:Rv2333c
uniprot id: P9WG91
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Multidrug resistance protein Stp
up seq anno feature ids: PRO_0000390886

83332:Rv2006
gene id: 83332:Rv2006
uniprot id: P9WN15
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton donor
up seq anno comments: Uncharacterized glycosyl hydrolase Rv2006
up seq anno feature ids: PRO_0000108019

83332:Rv1984c
gene id: 83332:Rv1984c
uniprot id: P9WP43
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno comments: 30% decrease in activity with pNP-octanoate and vinyl-caprylate as substrates.
up seq anno comments: Carboxylesterase Culp1
up seq anno comments: Loss of activity.
up seq anno comments: Nucleophile
up seq anno comments: Proton donor/acceptor
up seq anno comments: Shows a strong preference for substrates with a medium chain length ranging between 6 and 8 carbon atoms. 17-18% increase in activity with VC6 or VC8 as substrates. Acquires phospholipase A activity and shows cytotoxic effects on macrophages.
up seq anno comments: Shows a strong preference for substrates with a medium chain length ranging between 6 and 8 carbon atoms. 31% and 25% decrease in activity with 6 carbon atoms vinyl esters (VC6) or 8 carbon atoms vinyl esters (VC8) as substrates. Enhances lipase activity on triglycerides. Acquires phospholipase A activity and shows cytotoxic effects on macrophages.
up seq anno comments: Shows a strong preference for substrates with a medium chain length ranging between 6 and 8 carbon atoms. Loses 99% and 80% of activity with VC6 or VC8 as substrates. Loss of lipase activity.
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000006447

83332:Rv0407
gene id: 83332:Rv0407
uniprot id: P9WNE1
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: F420-dependent glucose-6-phosphate dehydrogenase
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000399504

83332:Rv3537
gene id: 83332:Rv3537
uniprot id: P71864
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: 3-oxosteroid 1-dehydrogenase
up seq anno feature ids: PRO_0000403952

83332:Rv2163c
gene id: 83332:Rv2163c
uniprot id: L0T911
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Acyl-ester intermediate
up seq anno comments: Cytoplasmic
up seq anno comments: Decreased interaction with Wag31. Loss of interaction, reduced protection from Rip1 proteolysis; when associated with 427-H--V-429 deletion.
up seq anno comments: Decreased interaction with Wag31. Loss of interaction, reduced protection from Rip1 proteolysis; when associated with 488-Q--S-490 deletion.
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: No degradation by Rip1.
up seq anno comments: No effect on degradation by Rip1.
up seq anno comments: Penicillin-binding protein PbpB
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000422679

83332:Rv2982c
gene id: 83332:Rv2982c
uniprot id: P9WN77
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Glycerol-3-phosphate dehydrogenase [NAD(P)+]
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000137996

83332:Rv3833
gene id: 83332:Rv3833
uniprot id: P96245
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH araC/xylS-type

83332:Rv1070c
gene id: 83332:Rv1070c
uniprot id: P9WNN9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Probable enoyl-CoA hydratase EchA8
up seq anno feature ids: PRO_0000109338

83332:Rv2457c
gene id: 83332:Rv2457c
uniprot id: P9WPB9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: ATP-dependent Clp protease ATP-binding subunit ClpX
up seq anno comments: ClpX-type ZB
up seq anno feature ids: PRO_0000160388

83332:Rv0528
gene id: 83332:Rv0528
uniprot id: O06394
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: ResB-like

83332:Rv3665c
gene id: 83332:Rv3665c
uniprot id: I6YGV9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: Helical

83332:Rv2276
gene id: 83332:Rv2276
uniprot id: P9WPP7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Considerable effects on the heme macrocycle conformation. Mutant leads to a more planar heme conformation.
up seq anno comments: Has little effect on the heme conformation but significantly alters the environment of the heme and the affinity for azoles.
up seq anno comments: Has little effect.
up seq anno comments: Important for the position of heme
up seq anno comments: Mycocyclosin synthase
up seq anno comments: No significant change.
up seq anno comments: Participates in a stacking interactions with the tyrosyl of cYY
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052274

83332:Rv1381
gene id: 83332:Rv1381
uniprot id: P9WHL3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Dihydroorotase
up seq anno feature ids: PRO_0000147244

83332:Rv0353
gene id: 83332:Rv0353
uniprot id: O06302
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno comments: HTH merR-type

83332:Rv0834c
gene id: 83332:Rv0834c
uniprot id: Q79FV6
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv1197
gene id: 83332:Rv1197
uniprot id: P9WNJ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxK
up seq anno feature ids: PRO_0000167803

83332:Rv0143c
gene id: 83332:Rv0143c
uniprot id: P96820
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1011
gene id: 83332:Rv1011
uniprot id: P9WKG7
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Propeptide
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Propeptide
up seq anno labels: Strand
up seq anno comments: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
up seq anno comments: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, propeptide removed
up seq anno comments: Removed
up seq anno comments: Removed; alternate
up seq anno feature ids: PRO_0000189235
up seq anno feature ids: PRO_0000455339
up seq anno feature ids: PRO_0000455340

83332:Rv3217c
gene id: 83332:Rv3217c
uniprot id: O05849
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1863c
gene id: 83332:Rv1863c
uniprot id: P95152
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1328
gene id: 83332:Rv1328
uniprot id: P9WMW1
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Glycogen phosphorylase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000188556

83332:Rv1502
gene id: 83332:Rv1502
uniprot id: P9WLW7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1502
up seq anno feature ids: PRO_0000103861

83332:Rv0974c
gene id: 83332:Rv0974c
uniprot id: O86318
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CoA carboxyltransferase C-terminal
up seq anno comments: CoA carboxyltransferase N-terminal
up seq anno comments: Probable biotin-dependent acyl-coenzyme A carboxylase beta2 subunit
up seq anno feature ids: PRO_0000452369

83332:Rv2683
gene id: 83332:Rv2683
uniprot id: I6X540
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: CBS

83332:Rv1676
gene id: 83332:Rv1676
uniprot id: O53923
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant

83332:Rv1164
gene id: 83332:Rv1164
uniprot id: O06562
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: NarG-like

83332:Rv2511
gene id: 83332:Rv2511
uniprot id: P9WIU1
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Exonuclease
up seq anno comments: Oligoribonuclease
up seq anno feature ids: PRO_0000111051

83332:Rv1640c
gene id: 83332:Rv1640c
uniprot id: P9WFU7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: DNA Binding
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: DNA Binding
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Lysine--tRNA ligase
up seq anno comments: Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX
up seq anno comments: OB
up seq anno comments: Phosphatidylglycerol lysyltransferase
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000152657

83332:Rv3340
gene id: 83332:Rv3340
uniprot id: O53390
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine

83332:Rv0045c
gene id: 83332:Rv0045c
uniprot id: I6XU97
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 55-fold decrease in catalytic activity.
up seq anno comments: 550-fold decrease in catalytic activity.
up seq anno comments: 9000-fold decrease in catalytic activity.
up seq anno comments: Esterase Rv0045c
up seq anno comments: Involved in substrate selectivity
up seq anno comments: Less sensitive to Zn(2+) inhibition.
up seq anno comments: No change in sensitivity to Zn(2+).
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000451571

83332:Rv1202
gene id: 83332:Rv1202
uniprot id: P9WHS9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Putative succinyl-diaminopimelate desuccinylase DapE
up seq anno feature ids: PRO_0000414592

83332:Rv2299c
gene id: 83332:Rv2299c
uniprot id: P9WMJ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: A; substrate-binding
up seq anno comments: B
up seq anno comments: C
up seq anno comments: Chaperone protein HtpG
up seq anno feature ids: PRO_0000062996

83332:Rv3161c
gene id: 83332:Rv3161c
uniprot id: O53311
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rieske

83332:Rv1279
gene id: 83332:Rv1279
uniprot id: P9WMV5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Proton acceptor
up seq anno comments: Uncharacterized GMC-type oxidoreductase Rv1279
up seq anno feature ids: PRO_0000205616

83332:Rv3491
gene id: 83332:Rv3491
uniprot id: I6XHD1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Secreted protein
up seq anno feature ids: PRO_5039573736

83332:Rv0375c
gene id: 83332:Rv0375c
uniprot id: I6Y7N2
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv0189c
gene id: 83332:Rv0189c
uniprot id: P9WKJ5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Dihydroxy-acid dehydratase
up seq anno comments: Loss of catalytic activity.
up seq anno comments: N-acetylproline
up seq anno comments: N6-carboxylysine
up seq anno comments: Proton acceptor
up seq anno comments: Removed
up seq anno comments: via carbamate group
up seq anno feature ids: PRO_0000103481

83332:Rv3304
gene id: 83332:Rv3304
uniprot id: O53356
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno comments: Proton acceptor

83332:Rv3814c
gene id: 83332:Rv3814c
uniprot id: O07809
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv0667
gene id: 83332:Rv0667
uniprot id: P9WGY9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Sequence Conflict
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: DNA-directed RNA polymerase subunit beta
up seq anno comments: Disordered
up seq anno comments: Does not affect association with TRCF, but weakens interaction with CarD.
up seq anno comments: In strain: RJ37; rifampicin-resistant.
up seq anno comments: In strain: RJ48; rifampicin-resistant.
up seq anno comments: In strain: RJ49; rifampicin-resistant.
up seq anno comments: In strain: RJ55; rifampicin-resistant.
up seq anno comments: In strain: SP28; rifampicin-resistant.
up seq anno comments: In strain: vr10; rifampicin-resistant.
up seq anno comments: In strain: vr11 and RJ37; rifampicin-resistant.
up seq anno comments: In strain: vr12 and SP22; rifampicin-resistant.
up seq anno comments: In strain: vr1; rifampicin-resistant.
up seq anno comments: In strain: vr2; rifampicin-resistant.
up seq anno comments: In strain: vr3; rifampicin-resistant.
up seq anno comments: In strain: vr4; rifampicin-resistant.
up seq anno comments: In strain: vr5; rifampicin-resistant.
up seq anno comments: In strain: vr6; rifampicin-resistant.
up seq anno comments: In strain: vr7; rifampicin-resistant.
up seq anno comments: In strain: vr8; rifampicin-resistant.
up seq anno comments: In strain: vr9; rifampicin-resistant.
up seq anno comments: Polar residues
up seq anno comments: Weakens interaction with TRCF and CarD.
up seq anno feature ids: PRO_0000047927

83332:Rv2467
gene id: 83332:Rv2467
uniprot id: L7N655
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Aminopeptidase N-like N-terminal
up seq anno comments: ERAP1-like C-terminal
up seq anno comments: Peptidase M1 membrane alanine aminopeptidase

83332:Rv0494
gene id: 83332:Rv0494
uniprot id: P9WMG7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH gntR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0494
up seq anno feature ids: PRO_0000050697

83332:Rv1338
gene id: 83332:Rv1338
uniprot id: P9WPW9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Glutamate racemase
up seq anno comments: Proton donor/acceptor
up seq anno feature ids: PRO_0000095489

83332:Rv1672c
gene id: 83332:Rv1672c
uniprot id: O53919
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Major facilitator superfamily (MFS) profile

83332:Rv2203
gene id: 83332:Rv2203
uniprot id: P9WLI7
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues
up seq anno comments: Uncharacterized protein Rv2203
up seq anno feature ids: PRO_0000103972

83332:Rv0312
gene id: 83332:Rv0312
uniprot id: O07239
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues
up seq anno comments: Pro residues

83332:Rv3435c
gene id: 83332:Rv3435c
uniprot id: O06252
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0671
gene id: 83332:Rv0671
uniprot id: I6XVY0
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5030172889

83332:Rv1177
gene id: 83332:Rv1177
uniprot id: O50433
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: 4Fe-4S ferredoxin-type
up seq anno comments: Disordered

83332:Rv2345
gene id: 83332:Rv2345
uniprot id: P9WFJ5
up seq anno parent labels: Chain
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Coiled-Coil
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: UPF0603 protein Rv2345
up seq anno feature ids: PRO_0000390675

83332:Rv0133
gene id: 83332:Rv0133
uniprot id: P96810
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: N-acetyltransferase

83332:Rv2862A
gene id: 83332:Rv2862A
uniprot id: P0CW32
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB23
up seq anno feature ids: PRO_0000408068

83332:Rv2859c
gene id: 83332:Rv2859c
uniprot id: O33341
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Domain Extent
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Glutamine amidotransferase type-1
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Nucleophile
up seq anno comments: Putative glutamine amidotransferase Rv2859c
up seq anno feature ids: PRO_0000396115

83332:Rv2175c
gene id: 83332:Rv2175c
uniprot id: O53509
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Abolishes DNA-binding activity.
up seq anno comments: DNA-binding protein Rv2175c
up seq anno comments: Disordered
up seq anno comments: Lack of phosphorylation. Retains DNA-binding activity.
up seq anno comments: Phosphothreonine
up seq anno feature ids: PRO_0000420875

83332:Rv2824c
gene id: 83332:Rv2824c
uniprot id: P9WPJ1
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: CRISPR-associated endoribonuclease Cas6
up seq anno comments: Disordered
up seq anno comments: Incorrect processing of pre-crRNA, binds pre-crRNA.
up seq anno comments: Incorrect processing of pre-crRNA, no longer binds pre-crRNA.
up seq anno feature ids: PRO_0000418222

83332:Rv0069c
gene id: 83332:Rv0069c
uniprot id: C7FLQ4
uniprot id: P9WGT5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: L-serine dehydratase
up seq anno comments: Serine dehydratase beta chain
up seq anno comments: Serine dehydratase-like alpha subunit
up seq anno feature ids: PRO_0000171909

83332:Rv2993c
gene id: 83332:Rv2993c
uniprot id: I6Y276
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Protein Rv2993c
up seq anno feature ids: PRO_0000456000

83332:Rv1289
gene id: 83332:Rv1289
uniprot id: P9WM37
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1289
up seq anno feature ids: PRO_0000103787

83332:Rv3843c
gene id: 83332:Rv3843c
uniprot id: P96235
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: DUF4328
up seq anno comments: Helical

83332:Rv2470
gene id: 83332:Rv2470
uniprot id: P9WN23
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Turn
up seq anno comments: 3',4'-dihydroxyphenylalanine; alternate
up seq anno comments: Group 2 truncated hemoglobin GlbO
up seq anno comments: Isodityrosine (Tyr-Tyr); alternate
up seq anno comments: proximal binding residue
up seq anno feature ids: PRO_0000162643

83332:Rv1081c
gene id: 83332:Rv1081c
uniprot id: O53429
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3316
gene id: 83332:Rv3316
uniprot id: O53368
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Removed
up seq anno comments: Succinate dehydrogenase 2 membrane subunit SdhC
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000432512

83332:Rv3675
gene id: 83332:Rv3675
uniprot id: I6YCQ7
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2289
gene id: 83332:Rv2289
uniprot id: P9WPG9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Probable CDP-diacylglycerol pyrophosphatase
up seq anno feature ids: PRO_0000198580

83332:Rv3116
gene id: 83332:Rv3116
uniprot id: L7N674
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Rhodanese

83332:Rv2692
gene id: 83332:Rv2692
uniprot id: P9WFZ3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: RCK C-terminal
up seq anno comments: RCK N-terminal
up seq anno comments: Trk system potassium uptake protein TrkA
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000148720

83332:Rv0015c
gene id: 83332:Rv0015c
uniprot id: P9WI83
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 10-fold reduction in transphosphorylation activity. This mutant strain shows severely compromised growth. Loss of autophosphorylation activity and weak transphosphorylation activity; when associated with A-174.
up seq anno comments: 4-fold reduction in transphosphorylation activity.
up seq anno comments: 5-fold reduction in transphosphorylation activity. Loss of autophosphorylation activity and weak transphosphorylation activity; when associated with A-172.
up seq anno comments: Activation loop
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Loss of auto- and transphosphorylation activity.
up seq anno comments: Loss of autophosphorylation activity. This mutation results in cell death.
up seq anno comments: Loss of transphosphorylation activity.
up seq anno comments: Phosphoserine; by autocatalysis
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Polar residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknA
up seq anno feature ids: PRO_0000171205

83332:Rv0934
gene id: 83332:Rv0934
uniprot id: P9WGU1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Phosphate-binding protein PstS 1
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000031854

83332:Rv1208
gene id: 83332:Rv1208
uniprot id: P9WMW9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Glucosyl-3-phosphoglycerate synthase
up seq anno feature ids: PRO_0000420163

83332:Rv1682
gene id: 83332:Rv1682
uniprot id: O33184
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil

83332:Rv2050
gene id: 83332:Rv2050
uniprot id: P9WHJ5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno comments: Not required for interaction with SigB
up seq anno comments: RNA polymerase-binding protein RbpA
up seq anno comments: Required for oligomerization and to complement a conditional disruption mutant
up seq anno feature ids: PRO_0000423656

83332:Rv0155
gene id: 83332:Rv0155
uniprot id: P96832
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
up seq anno comments: Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding

83332:Rv1021
gene id: 83332:Rv1021
uniprot id: P96379
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno comments: Important for catalytic activity
up seq anno comments: Nucleoside triphosphate pyrophosphohydrolase
up seq anno comments: Pyrophosphohydrolase activity is reduced 20-fold. It affects the magnesium binding and the protein structure.
up seq anno feature ids: PRO_0000401206

83332:Rv3227
gene id: 83332:Rv3227
uniprot id: P9WPY5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-phosphoshikimate 1-carboxyvinyltransferase
up seq anno comments: Disordered
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000088273

83332:Rv1514c
gene id: 83332:Rv1514c
uniprot id: P9WMX9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized glycosyltransferase Rv1514c
up seq anno feature ids: PRO_0000059249

83332:Rv2696c
gene id: 83332:Rv2696c
uniprot id: I6XF31
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv1686c
gene id: 83332:Rv1686c
uniprot id: O33188
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-2
up seq anno comments: Helical

83332:Rv2141c
gene id: 83332:Rv2141c
uniprot id: L7N684
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Peptidase M20 dimerisation

83332:Rv1652
gene id: 83332:Rv1652
uniprot id: P9WPZ9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N-acetyl-gamma-glutamyl-phosphate reductase
up seq anno feature ids: PRO_0000112424

83332:Rv3355c
gene id: 83332:Rv3355c
uniprot id: O50384
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1989c
gene id: 83332:Rv1989c
uniprot id: P9WLP9
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: NAD(+) phosphorylase MbcT
up seq anno comments: No change in toxicity.
up seq anno comments: No longer toxic, does not degrade NAD(+).
up seq anno comments: No longer toxic.
up seq anno comments: Reduced toxicity.
up seq anno feature ids: PRO_0000103918

83332:Rv1097c
gene id: 83332:Rv1097c
uniprot id: O53445
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Pro residues

83332:Rv2311
gene id: 83332:Rv2311
uniprot id: P9WLC1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2311
up seq anno feature ids: PRO_0000104020

83332:Rv3171c
gene id: 83332:Rv3171c
uniprot id: O53321
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Serine aminopeptidase S33

83332:Rv0057
gene id: 83332:Rv0057
uniprot id: P9WM77
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno comments: Uncharacterized protein Rv0057
up seq anno feature ids: PRO_0000014066

83332:Rv3502c
gene id: 83332:Rv3502c
uniprot id: O53547
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Hydroxyacyl-CoA dehydrogenase ChsB1
up seq anno feature ids: PRO_0000456535

83332:Rv3857c
gene id: 83332:Rv3857c
uniprot id: P96220
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1958c
gene id: 83332:Rv1958c
uniprot id: P95256
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv0711
gene id: 83332:Rv0711
uniprot id: P95059
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Sulfatase N-terminal

83332:Rv0678
gene id: 83332:Rv0678
uniprot id: I6Y8F7
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Variant
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Sequence Variant
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Decreases DNA binding.
up seq anno comments: H-T-H motif
up seq anno comments: HTH marR-type
up seq anno comments: HTH-type transcriptional regulator MmpR5
up seq anno comments: In CFZ-R1; leads to increased expression of mmpL5 and partial resistance to both clofazimine and bedaquiline.
up seq anno feature ids: PRO_0000432768

83332:Rv2608
gene id: 83332:Rv2608
uniprot id: P9WHZ5
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PE-PPE
up seq anno comments: Uncharacterized PPE family protein PPE42
up seq anno feature ids: PRO_0000379116

83332:Rv1389
gene id: 83332:Rv1389
uniprot id: P9WKE9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Guanylate kinase
up seq anno comments: Guanylate kinase-like
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000170570

83332:Rv0861c
gene id: 83332:Rv0861c
uniprot id: O53873
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: DEAH box
up seq anno comments: DNA helicase XPB
up seq anno comments: Helicase ATP-binding
up seq anno comments: Helicase C-terminal
up seq anno comments: Loss of ATPase activity.
up seq anno comments: Required for protein stability or solubility
up seq anno feature ids: PRO_0000455759

83332:Rv1031
gene id: 83332:Rv1031
uniprot id: P9WKF1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Potassium-transporting ATPase KdpC subunit
up seq anno feature ids: PRO_0000196999

83332:Rv0504c
gene id: 83332:Rv0504c
uniprot id: P9WFK3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: MaoC-like
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: UPF0336 protein Rv0504c
up seq anno feature ids: PRO_0000216142

83332:Rv1349
gene id: 83332:Rv1349
uniprot id: P9WQJ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: ABC transmembrane type-1
up seq anno comments: ABC transporter
up seq anno comments: Cytoplasmic
up seq anno comments: Helical
up seq anno comments: Mycobactin import ATP-binding/permease protein IrtB
up seq anno comments: Periplasmic
up seq anno feature ids: PRO_0000093257

83332:Rv2213
gene id: 83332:Rv2213
uniprot id: P9WHT3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable cytosol aminopeptidase
up seq anno feature ids: PRO_0000165771

83332:Rv3445c
gene id: 83332:Rv3445c
uniprot id: I6Y3I6
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxU
up seq anno feature ids: PRO_0000436935

83332:Rv0682
gene id: 83332:Rv0682
uniprot id: P9WH63
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Natural Variation
up seq anno parent labels: Region
up seq anno parent labels: Sequence Variant
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Sequence Variant
up seq anno comments: Disordered
up seq anno comments: In strain: 9106, 9181, An03, F12, F18 and TCVGH21; resistant to streptomycin.
up seq anno comments: In strain: C37; probably resistant to streptomycin.
up seq anno comments: In strain: F05; resistant to streptomycin.
up seq anno comments: In strain: F18; resistant to streptomycin.
up seq anno comments: In strain: TCVGH25; probably resistant to streptomycin.
up seq anno comments: Small ribosomal subunit protein uS12
up seq anno feature ids: PRO_0000146272

83332:Rv1187
gene id: 83332:Rv1187
uniprot id: O50443
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Aldehyde dehydrogenase
up seq anno comments: Disordered

83332:Rv3697A
gene id: 83332:Rv3697A
uniprot id: P9WJ15
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative antitoxin VapB48
up seq anno feature ids: PRO_0000408085

83332:Rv2870c
gene id: 83332:Rv2870c
uniprot id: P9WNS1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
up seq anno feature ids: PRO_0000163678

83332:Rv0982
gene id: 83332:Rv0982
uniprot id: P9WGL1
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Abolishes autophosphorylation as well as dephosphorylation of phospho-MprA.
up seq anno comments: Cytoplasmic
up seq anno comments: Disordered
up seq anno comments: Extracellular
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Polar residues
up seq anno comments: Signal transduction histidine-protein kinase/phosphatase MprB
up seq anno feature ids: PRO_0000308440

83332:Rv0079
gene id: 83332:Rv0079
uniprot id: P9WMA9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Dormancy associated translation inhibitor
up seq anno feature ids: PRO_0000392679

83332:Rv1843c
gene id: 83332:Rv1843c
uniprot id: P9WKI3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CBS 1
up seq anno comments: CBS 2
up seq anno comments: GMP reductase
up seq anno comments: Thioimidate intermediate
up seq anno feature ids: PRO_0000093785

83332:Rv3005c
gene id: 83332:Rv3005c
uniprot id: I6YAV3
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3554
gene id: 83332:Rv3554
uniprot id: P71846
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: 2Fe-2S ferredoxin-type
up seq anno comments: FAD-binding FR-type
up seq anno comments: Helical

83332:Rv1299
gene id: 83332:Rv1299
uniprot id: P9WHG3
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: N-acetylthreonine
up seq anno comments: N5-methylglutamine
up seq anno comments: Peptide chain release factor 1
up seq anno comments: Removed
up seq anno feature ids: PRO_0000177711

83332:Rv3518c
gene id: 83332:Rv3518c
uniprot id: P9WPL5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Steroid C26-monooxygenase
up seq anno comments: axial binding residue
up seq anno feature ids: PRO_0000052304

83332:Rv2482c
gene id: 83332:Rv2482c
uniprot id: P9WI61
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: Glycerol-3-phosphate acyltransferase
up seq anno comments: HXXXXD motif
up seq anno feature ids: PRO_0000195225

83332:Rv2838c
gene id: 83332:Rv2838c
uniprot id: P9WHJ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Ribosome-binding factor A
up seq anno feature ids: PRO_0000102698

83332:Rv1384
gene id: 83332:Rv1384
uniprot id: P9WPK3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ATP-grasp 1
up seq anno comments: ATP-grasp 2
up seq anno comments: Allosteric domain
up seq anno comments: Carbamoyl phosphate synthetic domain
up seq anno comments: Carbamoyl-phosphate synthase large chain
up seq anno comments: Carboxyphosphate synthetic domain
up seq anno comments: MGS-like
up seq anno comments: Oligomerization domain
up seq anno feature ids: PRO_0000145023

83332:Rv3330
gene id: 83332:Rv3330
uniprot id: O53380
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: 60% decrease in phosphorylation by PknH.
up seq anno comments: Acyl-ester intermediate
up seq anno comments: D-alanyl-D-alanine carboxypeptidase DacB1
up seq anno comments: Helical
up seq anno comments: Phosphothreonine; by PknH
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_5010219484

83332:Rv3197A
gene id: 83332:Rv3197A
uniprot id: Q6MX01
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mass
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: A.T hook
up seq anno comments: Fully oxidized recombinant protein tagged at both termini.
up seq anno comments: Fully reduced recombinant protein tagged at both termini.
up seq anno comments: Probable transcriptional regulator WhiB7
up seq anno feature ids: PRO_0000420387

83332:Rv0199
gene id: 83332:Rv0199
uniprot id: O53650
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv2855
gene id: 83332:Rv2855
uniprot id: P9WHH3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno comments: Mycothione reductase
up seq anno comments: Proton acceptor
up seq anno comments: Redox-active
up seq anno feature ids: PRO_0000399830

83332:Rv3130c
gene id: 83332:Rv3130c
uniprot id: P9WKC9
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N-acetylmethionine
up seq anno comments: Probable diacyglycerol O-acyltransferase tgs1
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_0000222916

83332:Rv0025
gene id: 83332:Rv0025
uniprot id: P9WMA1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0025
up seq anno feature ids: PRO_0000103642

83332:Rv1039c
gene id: 83332:Rv1039c
uniprot id: P9WI31
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: PPE family protein PPE15
up seq anno feature ids: PRO_0000378477

83332:Rv1219c
gene id: 83332:Rv1219c
uniprot id: O86312
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional regulatory protein RaaS
up seq anno comments: Reduces DNA binding affinity and ligand binding.
up seq anno feature ids: PRO_0000447332

83332:Rv0871
gene id: 83332:Rv0871
uniprot id: I6WZM9
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: CSD
up seq anno comments: Disordered

83332:Rv2954c
gene id: 83332:Rv2954c
uniprot id: I6X5U4
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Methyltransferase

83332:Rv2061c
gene id: 83332:Rv2061c
uniprot id: O86340
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Pyridoxamine 5'-phosphate oxidase putative

83332:Rv3457c
gene id: 83332:Rv3457c
uniprot id: P9WGZ1
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Alpha C-terminal domain (alpha-CTD)
up seq anno comments: Alpha N-terminal domain (alpha-NTD)
up seq anno comments: DNA-directed RNA polymerase subunit alpha
up seq anno feature ids: PRO_0000175345

83332:Rv0693
gene id: 83332:Rv0693
uniprot id: P9WJ79
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mycofactocin maturase MftC
up seq anno comments: Radical SAM core
up seq anno feature ids: PRO_0000415281

83332:Rv0171
gene id: 83332:Rv0171
uniprot id: O07415
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno comments: Pro residues

83332:Rv1696
gene id: 83332:Rv1696
uniprot id: P9WHI7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: DNA repair protein RecN
up seq anno feature ids: PRO_0000188022

83332:Rv2334
gene id: 83332:Rv2334
uniprot id: P9WP55
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: O-acetylserine sulfhydrylase
up seq anno feature ids: PRO_0000167094

83332:Rv2538c
gene id: 83332:Rv2538c
uniprot id: P9WPX9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Sequence Conflict
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Sequence Conflict
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-dehydroquinate synthase
up seq anno feature ids: PRO_0000140757

83332:Rv3907c
gene id: 83332:Rv3907c
uniprot id: L7N672
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HD/PDEase

83332:Rv0815c
gene id: 83332:Rv0815c
uniprot id: P9WHF9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Cysteine persulfide intermediate
up seq anno comments: Putative thiosulfate sulfurtransferase
up seq anno comments: Rhodanese 1
up seq anno comments: Rhodanese 2
up seq anno feature ids: PRO_0000139415

83332:Rv3365c
gene id: 83332:Rv3365c
uniprot id: Q93IG6
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Histidine kinase/HSP90-like ATPase
up seq anno comments: Pro residues

83332:Rv1999c
gene id: 83332:Rv1999c
uniprot id: P9WQM3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized transporter Rv1999c
up seq anno feature ids: PRO_0000054227

83332:Rv2848c
gene id: 83332:Rv2848c
uniprot id: P9WP97
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Site
up seq anno comments: GATase cobBQ-type
up seq anno comments: Hydrogenobyrinate a,c-diamide synthase
up seq anno comments: Increases nucleophilicity of active site Cys
up seq anno comments: Nucleophile
up seq anno feature ids: PRO_0000141262

83332:Rv2324
gene id: 83332:Rv2324
uniprot id: P71888
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HTH asnC-type

83332:Rv3182
gene id: 83332:Rv3182
uniprot id: O53332
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Putative toxin HigB3
up seq anno feature ids: PRO_0000432914

83332:Rv1832
gene id: 83332:Rv1832
uniprot id: P9WN53
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Probable glycine dehydrogenase (decarboxylating)
up seq anno feature ids: PRO_0000166920

83332:Rv3867
gene id: 83332:Rv3867
uniprot id: O69732
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: ESX-1 secretion-associated protein EspH
up seq anno feature ids: PRO_0000394146

83332:Rv0722
gene id: 83332:Rv0722
uniprot id: P9WHA3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL30
up seq anno feature ids: PRO_0000104599

83332:Rv1229c
gene id: 83332:Rv1229c
uniprot id: P9WJN7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Iron-sulfur cluster carrier protein
up seq anno feature ids: PRO_0000184938

83332:Rv1402
gene id: 83332:Rv1402
uniprot id: P9WMQ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Zinc Finger
up seq anno labels: Chain
up seq anno labels: Zinc Finger
up seq anno comments: C4-type
up seq anno comments: Probable primosomal protein N'
up seq anno feature ids: PRO_0000102129

83332:Rv2223c
gene id: 83332:Rv2223c
uniprot id: P9WHR5
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: AB hydrolase-1
up seq anno comments: Carboxylesterase B
up seq anno comments: Nucleophile
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000027327

83332:Rv1359
gene id: 83332:Rv1359
uniprot id: P9WM05
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv1359
up seq anno feature ids: PRO_0000103830

83332:Rv1199c
gene id: 83332:Rv1199c
uniprot id: P60230
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Transposase for insertion sequence element IS1081
up seq anno feature ids: PRO_0000211350

83332:Rv2883c
gene id: 83332:Rv2883c
uniprot id: P9WHK5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Disordered
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Uridylate kinase
up seq anno feature ids: PRO_0000143863

83332:Rv0992c
gene id: 83332:Rv0992c
uniprot id: O05575
up seq anno parent labels: Binding Site
up seq anno parent labels: Site
up seq anno labels: Binding Site

83332:Rv1854c
gene id: 83332:Rv1854c
uniprot id: P95160
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Type II NADH:quinone oxidoreductase Ndh
up seq anno feature ids: PRO_0000452727

83332:Rv3015c
gene id: 83332:Rv3015c
uniprot id: I6YAW3
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Cobalamin-independent methionine synthase MetE C-terminal/archaeal

83332:Rv3565
gene id: 83332:Rv3565
uniprot id: P96847
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Valine--pyruvate aminotransferase
up seq anno feature ids: PRO_0000450668

83332:Rv0480c
gene id: 83332:Rv0480c
uniprot id: P9WJ01
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: CN hydrolase
up seq anno comments: Hydrolase Rv0480c
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000213261

83332:Rv1657
gene id: 83332:Rv1657
uniprot id: P9WPY9
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Arginine repressor
up seq anno feature ids: PRO_0000205104

83332:Rv1309
gene id: 83332:Rv1309
uniprot id: P9WPU9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ATP synthase gamma chain
up seq anno feature ids: PRO_0000073318

83332:Rv1488
gene id: 83332:Rv1488
uniprot id: P9WPR9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1488
up seq anno feature ids: PRO_0000094060

83332:Rv3265c
gene id: 83332:Rv3265c
uniprot id: P9WMY3
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno comments: N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase
up seq anno comments: Removed
up seq anno feature ids: PRO_0000395354

83332:Rv1969
gene id: 83332:Rv1969
uniprot id: O53970
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Signal Peptide
up seq anno comments: Mammalian cell entry C-terminal
up seq anno comments: Mce/MlaD
up seq anno feature ids: PRO_5010295866

83332:Rv3691
gene id: 83332:Rv3691
uniprot id: O69659
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized membrane protein Rv3691
up seq anno feature ids: PRO_0000415511

83332:Rv0394c
gene id: 83332:Rv0394c
uniprot id: P95202
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv0037c
gene id: 83332:Rv0037c
uniprot id: P9WJY1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized MFS-type transporter Rv0037c
up seq anno feature ids: PRO_0000103654

83332:Rv0883c
gene id: 83332:Rv0883c
uniprot id: P9WKQ7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv0883c
up seq anno feature ids: PRO_0000103725

83332:Rv2636
gene id: 83332:Rv2636
uniprot id: P9WL55
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative O-phosphotransferase Rv2636
up seq anno feature ids: PRO_0000104076

83332:Rv3506
gene id: 83332:Rv3506
uniprot id: O53551
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Medium/long-chain-fatty-acid--CoA ligase FadD17
up seq anno feature ids: PRO_0000406787

83332:Rv2964
gene id: 83332:Rv2964
uniprot id: P9WHM3
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: ACT
up seq anno comments: Disordered
up seq anno comments: Formyltetrahydrofolate deformylase
up seq anno comments: Pro residues
up seq anno feature ids: PRO_0000074964

83332:Rv0213c
gene id: 83332:Rv0213c
uniprot id: P96395
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: B12-binding
up seq anno comments: Radical SAM core

83332:Rv3830c
gene id: 83332:Rv3830c
uniprot id: P96248
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type

83332:Rv3467
gene id: 83332:Rv3467
uniprot id: Q50655
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: HNH nuclease

83332:Rv0703
gene id: 83332:Rv0703
uniprot id: P9WHB9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein uL23
up seq anno feature ids: PRO_0000129421

83332:Rv0181c
gene id: 83332:Rv0181c
uniprot id: P9WI85
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative quercetin 2,3-dioxygenase Rv0181c
up seq anno feature ids: PRO_0000214065

83332:Rv3662c
gene id: 83332:Rv3662c
uniprot id: I6YCP7
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Fido

83332:Rv2768c
gene id: 83332:Rv2768c
uniprot id: Q79FA9
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PPE
up seq anno comments: PPE family C-terminal

83332:Rv2397c
gene id: 83332:Rv2397c
uniprot id: P9WQM1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ABC transporter
up seq anno comments: N-acetylthreonine
up seq anno comments: Removed
up seq anno comments: Sulfate/thiosulfate import ATP-binding protein CysA
up seq anno feature ids: PRO_0000092276

83332:Rv1365c
gene id: 83332:Rv1365c
uniprot id: P9WGE3
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Mutagenesis Site
up seq anno comments: Anti-sigma-F factor antagonist RsfA
up seq anno comments: Constitutive interaction with RsbW; leads to active SigF.
up seq anno comments: STAS
up seq anno feature ids: PRO_0000194209

83332:Rv2548
gene id: 83332:Rv2548
uniprot id: P9WF93
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC19
up seq anno feature ids: PRO_0000407878

83332:Rv2195
gene id: 83332:Rv2195
uniprot id: P9WH23
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Disulfide Bond
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Transmembrane
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Disulfide Bond
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Region
up seq anno labels: Strand
up seq anno labels: Transmembrane
up seq anno labels: Turn
up seq anno comments: Cytochrome bc1 complex Rieske iron-sulfur subunit
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Rieske
up seq anno feature ids: PRO_0000127792

83332:Rv3029c
gene id: 83332:Rv3029c
uniprot id: P9WNG7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Electron transfer flavoprotein subunit beta
up seq anno feature ids: PRO_0000167882

83332:Rv0826
gene id: 83332:Rv0826
uniprot id: O53837
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic

83332:Rv2010
gene id: 83332:Rv2010
uniprot id: P9WF97
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC15
up seq anno feature ids: PRO_0000103939

83332:Rv2377c
gene id: 83332:Rv2377c
uniprot id: P9WIP5
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Protein MbtH
up seq anno feature ids: PRO_0000096276

83332:Rv2668
gene id: 83332:Rv2668
uniprot id: P71965
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5038914692

83332:Rv1762c
gene id: 83332:Rv1762c
uniprot id: O06797
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Encapsulin nanocompartment protein Rv1762c
up seq anno feature ids: PRO_0000455334

83332:Rv3153
gene id: 83332:Rv3153
uniprot id: P9WJG9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: 4Fe-4S ferredoxin-type 1
up seq anno comments: 4Fe-4S ferredoxin-type 2
up seq anno comments: Disordered
up seq anno comments: NADH-quinone oxidoreductase subunit I
up seq anno feature ids: PRO_0000118729

83332:Rv0404
gene id: 83332:Rv0404
uniprot id: P9WQ57
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Probable long-chain-fatty-acid--AMP ligase FadD30
up seq anno feature ids: PRO_0000406631

83332:Rv0732
gene id: 83332:Rv0732
uniprot id: P9WGN3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Protein translocase subunit SecY
up seq anno feature ids: PRO_0000131732

83332:Rv2498c
gene id: 83332:Rv2498c
uniprot id: P9WPE1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Citrate lyase subunit beta-like protein
up seq anno feature ids: PRO_0000286388

83332:Rv2974c
gene id: 83332:Rv2974c
uniprot id: I6Y259
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: DhaL

83332:Rv0224c
gene id: 83332:Rv0224c
uniprot id: P9WJZ9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized methyltransferase Rv0224c
up seq anno feature ids: PRO_0000380608

83332:Rv1412
gene id: 83332:Rv1412
uniprot id: P9WK35
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Repeat
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Repeat
up seq anno comments: Lumazine-binding 1
up seq anno comments: Lumazine-binding 2
up seq anno comments: Riboflavin synthase
up seq anno comments: in other chain
up seq anno feature ids: PRO_0000068168

83332:Rv1087
gene id: 83332:Rv1087
uniprot id: Q79FT0
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE

83332:Rv1895
gene id: 83332:Rv1895
uniprot id: O07737
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable zinc-binding alcohol dehydrogenase Rv1895
up seq anno feature ids: PRO_0000415504

83332:Rv2067c
gene id: 83332:Rv2067c
uniprot id: P9WLL9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2067c
up seq anno feature ids: PRO_0000103943

83332:Rv1708
gene id: 83332:Rv1708
uniprot id: P9WLT1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Uncharacterized protein Rv1708
up seq anno feature ids: PRO_0000390677

83332:Rv2894c
gene id: 83332:Rv2894c
uniprot id: P9WF35
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: Core-binding (CB)
up seq anno comments: O-(3'-phospho-DNA)-tyrosine intermediate
up seq anno comments: Tyr recombinase
up seq anno comments: Tyrosine recombinase XerC
up seq anno feature ids: PRO_0000095306

83332:Rv0349
gene id: 83332:Rv0349
uniprot id: O06300
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv1529
gene id: 83332:Rv1529
uniprot id: O53903
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: AMP-dependent synthetase/ligase

83332:Rv2389c
gene id: 83332:Rv2389c
uniprot id: I6Y0L9
uniprot id: P9WG27
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Non-terminal Residue
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Non-terminal Residue
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Resuscitation-promoting factor RpfD
up seq anno comments: Resuscitation-promoting factor core lysozyme-like
up seq anno feature ids: PRO_0000421030

83332:Rv0491
gene id: 83332:Rv0491
uniprot id: P9WGL9
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-aspartylphosphate
up seq anno comments: Cannot complement the deletion mutant.
up seq anno comments: Does not affect phosphorylation by PknB. Does not affect transcriptional activity.
up seq anno comments: Does not affect phosphorylation by PknB. Inactivates transcriptional activity.
up seq anno comments: OmpR/PhoB-type
up seq anno comments: Phosphothreonine; by PknB; in inhibited form
up seq anno comments: Response regulatory
up seq anno comments: Sensory transduction protein RegX3
up seq anno comments: Significantly reduces phosphorylation by PknB. Inactivates transcriptional activity.
up seq anno comments: Significantly reduces phosphorylation by PknB. Inactivates transcriptional activity. Significantly reduces the binding affinity of RegX3 for its target DNA sequence.
up seq anno comments: Slightly reduces phosphorylation by PknB. Inactivates transcriptional activity. Significantly reduces the binding affinity of RegX3 for its target DNA sequence.
up seq anno feature ids: PRO_0000081334

83332:Rv1353c
gene id: 83332:Rv1353c
uniprot id: P9WMD3
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: HTH-type transcriptional repressor Rv1353c
up seq anno feature ids: PRO_0000070662

83332:Rv1319c
gene id: 83332:Rv1319c
uniprot id: P9WQ31
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: Guanylate cyclase
up seq anno comments: HAMP
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv1319c
up seq anno feature ids: PRO_0000195754

83332:Rv3345c
gene id: 83332:Rv3345c
uniprot id: Q6MWY0
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Polar residues

83332:Rv0745
gene id: 83332:Rv0745
uniprot id: I6X9N8
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3880c
gene id: 83332:Rv3880c
uniprot id: P9WJB9
up seq anno parent labels: Chain
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno comments: ESX-1 secretion-associated protein EspL
up seq anno comments: N-acetylserine
up seq anno comments: Removed
up seq anno feature ids: PRO_0000394150

83332:Rv1979c
gene id: 83332:Rv1979c
uniprot id: P9WQM5
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized transporter Rv1979c
up seq anno feature ids: PRO_0000054225

83332:Rv3701c
gene id: 83332:Rv3701c
uniprot id: P9WN47
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Histidine N-alpha-methyltransferase
up seq anno feature ids: PRO_0000413652

83332:Rv0047c
gene id: 83332:Rv0047c
uniprot id: P71704
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil
up seq anno labels: Domain Extent
up seq anno comments: Transcription regulator PadR N-terminal

83332:Rv0893c
gene id: 83332:Rv0893c
uniprot id: P9WFI1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0893c
up seq anno feature ids: PRO_0000103733

83332:Rv2646
gene id: 83332:Rv2646
uniprot id: I6XEU5
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Core-binding (CB)
up seq anno comments: Tyr recombinase

83332:Rv3840
gene id: 83332:Rv3840
uniprot id: P96238
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Cell envelope-related transcriptional attenuator

83332:Rv3483c
gene id: 83332:Rv3483c
uniprot id: I6X7F2
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Polar residues

83332:Rv0713
gene id: 83332:Rv0713
uniprot id: I6WZ58
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv1551
gene id: 83332:Rv1551
uniprot id: P9WI59
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Motif
up seq anno comments: HXXXXD motif
up seq anno comments: Putative acyltransferase plsB1
up seq anno feature ids: PRO_0000195244

83332:Rv2911
gene id: 83332:Rv2911
uniprot id: I6Y204
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Signal Peptide
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-ester intermediate
up seq anno comments: D-alanyl-D-alanine carboxypeptidase DacB2
up seq anno comments: Proton acceptor
up seq anno feature ids: PRO_5010244966

83332:Rv0186
gene id: 83332:Rv0186
uniprot id: O07430
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Fibronectin type III-like

83332:Rv0524
gene id: 83332:Rv0524
uniprot id: P9WMN9
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Modified Residue
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Glutamate-1-semialdehyde 2,1-aminomutase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno comments: Polar residues
up seq anno feature ids: PRO_0000120425

83332:Rv2904c
gene id: 83332:Rv2904c
uniprot id: P9WHC9
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Large ribosomal subunit protein bL19
up seq anno feature ids: PRO_0000163494

83332:Rv1014c
gene id: 83332:Rv1014c
uniprot id: P9WHN7
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Peptidyl-tRNA hydrolase
up seq anno feature ids: PRO_0000187780

83332:Rv1378c
gene id: 83332:Rv1378c
uniprot id: P71806
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: HNH nuclease

83332:Rv2558
gene id: 83332:Rv2558
uniprot id: P9WLA3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2558
up seq anno feature ids: PRO_0000104037

83332:Rv1205
gene id: 83332:Rv1205
uniprot id: O05306
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Mutagenesis Site
up seq anno comments: Abrogates pupylation. This mutant accumulates in M.tuberculosis with a functional proteasome system and sensitizes M.tuberculosis to NO. Decrease in catalytic activity.
up seq anno comments: Cytokinin riboside 5'-monophosphate phosphoribohydrolase
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: Large decrease in catalytic activity.
up seq anno comments: Loss of catalytic activity.
up seq anno feature ids: PRO_0000433000

83332:Rv0840c
gene id: 83332:Rv0840c
uniprot id: I6Y8X0
up seq anno parent labels: Active Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Domain Extent
up seq anno comments: AB hydrolase-1
up seq anno comments: Nucleophile
up seq anno comments: Proton donor

83332:Rv3787c
gene id: 83332:Rv3787c
uniprot id: P9WFH3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Putative S-adenosyl-L-methionine-dependent methyltransferase Rv3787c
up seq anno feature ids: PRO_0000361241

83332:Rv1669
gene id: 83332:Rv1669
uniprot id: O86371
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv2872
gene id: 83332:Rv2872
uniprot id: P9WF55
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC43
up seq anno feature ids: PRO_0000104087

83332:Rv3429
gene id: 83332:Rv3429
uniprot id: P9WHY1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE59
up seq anno feature ids: PRO_0000217855

83332:Rv3721c
gene id: 83332:Rv3721c
uniprot id: P9WNT9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: DNA polymerase III subunit gamma/tau
up seq anno comments: Disordered
up seq anno feature ids: PRO_0000105500

83332:Rv2679
gene id: 83332:Rv2679
uniprot id: I6YA03
up seq anno parent labels: Region
up seq anno labels: Region
up seq anno comments: Disordered

83332:Rv3201c
gene id: 83332:Rv3201c
uniprot id: O53347
up seq anno parent labels: Binding Site
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Domain Extent
up seq anno comments: UvrD-like helicase ATP-binding
up seq anno comments: UvrD-like helicase C-terminal

83332:Rv3164c
gene id: 83332:Rv3164c
uniprot id: O53314
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: ATPase AAA-3
up seq anno comments: ChlI/MoxR AAA lid

83332:Rv0414c
gene id: 83332:Rv0414c
uniprot id: P9WG75
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Thiamine-phosphate synthase
up seq anno feature ids: PRO_0000157026

83332:Rv3546
gene id: 83332:Rv3546
uniprot id: I6XHI4
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Proton acceptor
up seq anno comments: Steroid 3-ketoacyl-CoA thiolase
up seq anno feature ids: PRO_0000438502

83332:Rv2508c
gene id: 83332:Rv2508c
uniprot id: O06171
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3352c
gene id: 83332:Rv3352c
uniprot id: O50381
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: FAD-binding PCMH-type

83332:Rv2984
gene id: 83332:Rv2984
uniprot id: A5YKM2
uniprot id: P9WHV9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Phosphohistidine intermediate
up seq anno comments: Polyphosphate kinase
up seq anno comments: Polyphosphate kinase C-terminal
up seq anno comments: Polyphosphate kinase N-terminal
up seq anno comments: Polyphosphate kinase middle
up seq anno feature ids: PRO_0000128648

83332:Rv0234c
gene id: 83332:Rv0234c
uniprot id: P9WNX9
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Nucleophile
up seq anno comments: Proton acceptor
up seq anno comments: Succinate-semialdehyde dehydrogenase [NADP(+)] 1
up seq anno feature ids: PRO_0000310705

83332:Rv3168
gene id: 83332:Rv3168
uniprot id: P9WI99
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Proton acceptor
up seq anno comments: Putative aminoglycoside phosphotransferase
up seq anno feature ids: PRO_0000420881

83332:Rv1172c
gene id: 83332:Rv1172c
uniprot id: L7N693
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: PE

83332:Rv1905c
gene id: 83332:Rv1905c
uniprot id: P9WP27
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Probable D-amino-acid oxidase
up seq anno feature ids: PRO_0000390617

83332:Rv3048c
gene id: 83332:Rv3048c
uniprot id: P9WH71
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Turn
up seq anno comments: Ribonucleoside-diphosphate reductase subunit beta nrdF2
up seq anno feature ids: PRO_0000393356

83332:Rv0537c
gene id: 83332:Rv0537c
uniprot id: O06403
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical

83332:Rv3672c
gene id: 83332:Rv3672c
uniprot id: I6XHX8
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Nudix hydrolase
up seq anno comments: Polar residues

83332:Rv0897c
gene id: 83332:Rv0897c
uniprot id: P9WKP7
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv0897c
up seq anno feature ids: PRO_0000103737

83332:Rv2077c
gene id: 83332:Rv2077c
uniprot id: P9WLL1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Uncharacterized protein Rv2077c
up seq anno feature ids: PRO_0000014120

83332:Rv1719
gene id: 83332:Rv1719
uniprot id: P71977
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH iclR-type
up seq anno comments: HTH-type transcriptional regulator Rv1719
up seq anno comments: IclR-ED
up seq anno feature ids: PRO_0000458114

83332:Rv2570
gene id: 83332:Rv2570
uniprot id: P9WL91
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2570
up seq anno feature ids: PRO_0000104050

83332:Rv0362
gene id: 83332:Rv0362
uniprot id: O06312
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Domain Extent
up seq anno labels: Transmembrane
up seq anno comments: CBS
up seq anno comments: Helical

83332:Rv1539
gene id: 83332:Rv1539
uniprot id: P9WK99
up seq anno parent labels: Active Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Transmembrane
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno comments: Lipoprotein signal peptidase
up seq anno feature ids: PRO_0000178798

83332:Rv2401
gene id: 83332:Rv2401
uniprot id: O86326
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered

83332:Rv1875
gene id: 83332:Rv1875
uniprot id: O07754
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Pyridoxamine 5'-phosphate oxidase putative

83332:Rv0501
gene id: 83332:Rv0501
uniprot id: P9WKT3
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv0501
up seq anno feature ids: PRO_0000103707

83332:Rv3588c
gene id: 83332:Rv3588c
uniprot id: P9WPJ9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Carbonic anhydrase 2
up seq anno feature ids: PRO_0000396117

83332:Rv2200c
gene id: 83332:Rv2200c
uniprot id: P9WP69
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Transmembrane
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Cytochrome c oxidase subunit 2
up seq anno comments: Disordered
up seq anno comments: Helical
up seq anno feature ids: PRO_0000006058

83332:Rv2693c
gene id: 83332:Rv2693c
uniprot id: I6X548
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv1174c
gene id: 83332:Rv1174c
uniprot id: O50430
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Signal Peptide
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno feature ids: PRO_5038345113

83332:Rv0759c
gene id: 83332:Rv0759c
uniprot id: P9WML3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Motif
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Motif
up seq anno comments: HIT
up seq anno comments: Histidine triad motif
up seq anno comments: Uncharacterized HIT-like protein Rv0759c
up seq anno feature ids: PRO_0000109825

83332:Rv3890c
gene id: 83332:Rv3890c
uniprot id: P9WNI1
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: ESAT-6-like protein EsxC
up seq anno feature ids: PRO_0000167818

83332:Rv1991c
gene id: 83332:Rv1991c
uniprot id: P9WII3
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Strand
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Endoribonuclease MazF6
up seq anno feature ids: PRO_0000201904

83332:Rv2518c
gene id: 83332:Rv2518c
uniprot id: I6Y9J2
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Lipid Binding
up seq anno parent labels: Modification
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Lipid Binding
up seq anno labels: Mutagenesis Site
up seq anno labels: Signal Peptide
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Binds to carbapenem drug (covalent)
up seq anno comments: Decreases stability of the covalent enzyme-meropenem adduct.
up seq anno comments: L,D-TPase catalytic
up seq anno comments: L,D-transpeptidase 2
up seq anno comments: N-palmitoyl cysteine
up seq anno comments: Nucleophile
up seq anno comments: Proton donor/acceptor
up seq anno comments: S-diacylglycerol cysteine
up seq anno feature ids: PRO_0000430334

83332:Rv3711c
gene id: 83332:Rv3711c
uniprot id: O69678
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Exonuclease

83332:Rv2658c
gene id: 83332:Rv2658c
uniprot id: P9WL47
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2658c
up seq anno feature ids: PRO_0000104082

83332:Rv3534c
gene id: 83332:Rv3534c
uniprot id: P9WMK5
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 4-hydroxy-2-oxohexanoate aldolase
up seq anno comments: Abolishes substrate channeling to HsaG.
up seq anno comments: Proton acceptor
up seq anno comments: Pyruvate carboxyltransferase
up seq anno comments: Transition state stabilizer
up seq anno feature ids: PRO_0000387862

83332:Rv1422
gene id: 83332:Rv1422
uniprot id: P9WMU5
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Lack of phosphorylation.
up seq anno comments: Phosphothreonine
up seq anno comments: Putative gluconeogenesis factor
up seq anno feature ids: PRO_0000107811

83332:Rv1361c
gene id: 83332:Rv1361c
uniprot id: P9WI25
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Uncharacterized PPE family protein PPE19
up seq anno feature ids: PRO_0000217845

83332:Rv1561
gene id: 83332:Rv1561
uniprot id: P9WFA5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: PINc
up seq anno comments: Ribonuclease VapC11
up seq anno feature ids: PRO_0000103883

83332:Rv3313c
gene id: 83332:Rv3313c
uniprot id: P63907
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Site
up seq anno comments: Adenosine deaminase
up seq anno comments: Important for catalytic activity
up seq anno comments: Proton donor
up seq anno feature ids: PRO_0000194374

83332:Rv0196
gene id: 83332:Rv0196
uniprot id: P9WME1
up seq anno parent labels: Chain
up seq anno parent labels: DNA Binding
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: DNA Binding
up seq anno labels: Domain Extent
up seq anno comments: H-T-H motif
up seq anno comments: HTH tetR-type
up seq anno comments: Uncharacterized HTH-type transcriptional regulator Rv0196
up seq anno feature ids: PRO_0000382632

83332:Rv1024
gene id: 83332:Rv1024
uniprot id: P96376
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Region
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Pro residues

83332:Rv1391
gene id: 83332:Rv1391
uniprot id: P9WNZ1
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Coenzyme A biosynthesis bifunctional protein CoaBC
up seq anno comments: Phosphopantothenate--cysteine ligase
up seq anno comments: Phosphopantothenoylcysteine decarboxylase
up seq anno feature ids: PRO_0000232694

83332:Rv0022c
gene id: 83332:Rv0022c
uniprot id: P71592
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Mass
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Mass
up seq anno comments: 4Fe-4S Wbl-type
up seq anno comments: Fully oxidized recombinant protein tagged at both termini.
up seq anno comments: Fully reduced recombinant protein tagged at both termini.
up seq anno comments: Transcriptional regulator WhiB5
up seq anno feature ids: PRO_0000420384

83332:Rv0853c
gene id: 83332:Rv0853c
uniprot id: P9WG37
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Alpha-keto-acid decarboxylase
up seq anno comments: Thiamine pyrophosphate binding
up seq anno feature ids: PRO_0000333751

83332:Rv2591
gene id: 83332:Rv2591
uniprot id: P9WIE9
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: PE
up seq anno comments: Uncharacterized PE-PGRS family protein PE_PGRS44
up seq anno feature ids: PRO_0000216169

83332:Rv1679
gene id: 83332:Rv1679
uniprot id: O53926
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Acyl-CoA dehydrogenase/oxidase C-terminal
up seq anno comments: Acyl-CoA dehydrogenase/oxidase N-terminal
up seq anno comments: Acyl-CoA oxidase/dehydrogenase middle

83332:Rv0824c
gene id: 83332:Rv0824c
uniprot id: P9WNZ7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Region
up seq anno comments: Basic and acidic residues
up seq anno comments: Disordered
up seq anno comments: Putative acyl-[acyl-carrier-protein] desaturase DesA1
up seq anno feature ids: PRO_0000392675

83332:Rv1511
gene id: 83332:Rv1511
uniprot id: P71790
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: NAD(P)-binding

83332:Rv3732
gene id: 83332:Rv3732
uniprot id: O69699
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno parent labels: Signal Peptide
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Signal Peptide
up seq anno labels: Transmembrane
up seq anno comments: Helical
up seq anno feature ids: PRO_5010314128

83332:Rv2357c
gene id: 83332:Rv2357c
uniprot id: P9WFV7
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Modified Residue
up seq anno comments: Glycine--tRNA ligase
up seq anno comments: N6-acetyllysine
up seq anno feature ids: PRO_0000072969

83332:Rv3212
gene id: 83332:Rv3212
uniprot id: O05854
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3556c
gene id: 83332:Rv3556c
uniprot id: I6XHJ3
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Acyl-thioester intermediate
up seq anno comments: Proton acceptor
up seq anno comments: Steroid 3-ketoacyl-CoA thiolase FadA6
up seq anno feature ids: PRO_0000452312

83332:Rv2182c
gene id: 83332:Rv2182c
uniprot id: O53516
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Phospholipid/glycerol acyltransferase

83332:Rv2995c
gene id: 83332:Rv2995c
uniprot id: P9WKK9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Site
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: 3-isopropylmalate dehydrogenase
up seq anno comments: Important for catalysis
up seq anno feature ids: PRO_0000083803

83332:Rv0245
gene id: 83332:Rv0245
uniprot id: O53667
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Flavin reductase like

83332:Rv0055
gene id: 83332:Rv0055
uniprot id: P9WH49
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein bS18A
up seq anno feature ids: PRO_0000111190

83332:Rv3850
gene id: 83332:Rv3850
uniprot id: P96227
up seq anno parent labels: Coiled-Coil
up seq anno parent labels: Region
up seq anno labels: Coiled-Coil

83332:Rv1094
gene id: 83332:Rv1094
uniprot id: P9WNZ5
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Crosslink
up seq anno parent labels: Helix
up seq anno parent labels: Initiator Methionine
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Crosslink
up seq anno labels: Helix
up seq anno labels: Initiator Methionine
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
up seq anno comments: N-acetylalanine
up seq anno comments: Putative acyl-[acyl-carrier-protein] desaturase DesA2
up seq anno comments: Removed
up seq anno feature ids: PRO_0000392676

83332:Rv0053
gene id: 83332:Rv0053
uniprot id: P9WH31
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno labels: Chain
up seq anno comments: Small ribosomal subunit protein bS6
up seq anno feature ids: PRO_0000176802

83332:Rv3119
gene id: 83332:Rv3119
uniprot id: P9WJR3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Strand
up seq anno comments: Molybdopterin synthase catalytic subunit 1
up seq anno feature ids: PRO_0000163087

83332:Rv3683
gene id: 83332:Rv3683
uniprot id: I6X827
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: Calcineurin-like phosphoesterase

83332:Rv0907
gene id: 83332:Rv0907
uniprot id: O05900
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno labels: Region
up seq anno comments: Beta-lactamase-related
up seq anno comments: Disordered
up seq anno comments: Peptidase S12 Pab87-related C-terminal

83332:Rv2088
gene id: 83332:Rv2088
uniprot id: P9WI67
up seq anno parent labels: Active Site
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Compositionally Biased Region
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Site
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Active Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Compositionally Biased Region
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Region
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Cytoplasmic
up seq anno comments: Decreases phosphorylation.
up seq anno comments: Disordered
up seq anno comments: Does not affect phosphorylation.
up seq anno comments: Does not affect phosphorylation. Lack of phosphorylation; when associated with A-171 and A-173.
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Lack of kinase activity.
up seq anno comments: Lack of phosphorylation.
up seq anno comments: Lack of phosphorylation; when associated with A-168 and A-171.
up seq anno comments: Lack of phosphorylation; when associated with A-168 and A-173.
up seq anno comments: Phosphothreonine; by autocatalysis
up seq anno comments: Polar residues
up seq anno comments: Protein kinase
up seq anno comments: Proton acceptor
up seq anno comments: Serine/threonine-protein kinase PknJ
up seq anno feature ids: PRO_0000171222

83332:Rv3488
gene id: 83332:Rv3488
uniprot id: I6X7F9
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Experimental Information
up seq anno parent labels: Helix
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Mutagenesis Site
up seq anno labels: Strand
up seq anno comments: Abolishes cadmium and zinc binding.
up seq anno comments: Transcriptional regulator Rv3488
up seq anno feature ids: PRO_0000447364

83332:Rv2581c
gene id: 83332:Rv2581c
uniprot id: P9WMW3
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Site
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno comments: Uncharacterized protein Rv2581c
up seq anno feature ids: PRO_0000192361

83332:Rv0372c
gene id: 83332:Rv0372c
uniprot id: O53707
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: XdhC Rossmann
up seq anno comments: XdhC- CoxI

83332:Rv1216c
gene id: 83332:Rv1216c
uniprot id: O05317
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv2412
gene id: 83332:Rv2412
uniprot id: P9WH41
up seq anno parent labels: Chain
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Region
up seq anno labels: Chain
up seq anno labels: Region
up seq anno comments: Disordered
up seq anno comments: Small ribosomal subunit protein bS20
up seq anno feature ids: PRO_0000167997

83332:Rv0513
gene id: 83332:Rv0513
uniprot id: O33358
up seq anno parent labels: Region
up seq anno parent labels: Transmembrane
up seq anno labels: Transmembrane
up seq anno comments: Helical

83332:Rv3237c
gene id: 83332:Rv3237c
uniprot id: O05882
up seq anno parent labels: Domain Extent
up seq anno parent labels: Region
up seq anno labels: Domain Extent
up seq anno comments: RCK C-terminal

83332:Rv1028c
gene id: 83332:Rv1028c
uniprot id: P9WGL3
up seq anno parent labels: Chain
up seq anno parent labels: Domain Extent
up seq anno parent labels: Experimental Information
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Mutagenesis Site
up seq anno parent labels: Region
up seq anno parent labels: Topological Domain
up seq anno parent labels: Transmembrane
up seq anno labels: Chain
up seq anno labels: Domain Extent
up seq anno labels: Modified Residue
up seq anno labels: Mutagenesis Site
up seq anno labels: Topological Domain
up seq anno labels: Transmembrane
up seq anno comments: Complete loss of autophosphorylation.
up seq anno comments: Cytoplasmic
up seq anno comments: Extracellular
up seq anno comments: Helical
up seq anno comments: Histidine kinase
up seq anno comments: Phosphohistidine; by autocatalysis
up seq anno comments: Sensor protein KdpD
up seq anno feature ids: PRO_0000074773

83332:Rv2210c
gene id: 83332:Rv2210c
uniprot id: P9WQ75
up seq anno parent labels: Binding Site
up seq anno parent labels: Chain
up seq anno parent labels: Helix
up seq anno parent labels: Modification
up seq anno parent labels: Modified Residue
up seq anno parent labels: Molecule Processing
up seq anno parent labels: Secondary Structure
up seq anno parent labels: Site
up seq anno parent labels: Strand
up seq anno parent labels: Turn
up seq anno labels: Binding Site
up seq anno labels: Chain
up seq anno labels: Helix
up seq anno labels: Modified Residue
up seq anno labels: Strand
up seq anno labels: Turn
up seq anno comments: Branched-chain-amino-acid aminotransferase
up seq anno comments: N6-(pyridoxal phosphate)lysine
up seq anno feature ids: PRO_0000103274