ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycosyltransferase subfamily 4-like N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aminoacyl-transfer RNA synthetases class-II family profile
Polysaccharide biosynthesis protein C-terminal
tRNA nucleotidyltransferase substrate binding
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Cleavage (non-hydrolytic); by autocatalysis
Schiff-base intermediate with substrate; via pyruvic acid
Fructose-1,6-bisphosphate aldolase/phosphatase
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
CobB/CobQ-like glutamine amidotransferase
Transcription factor NikR nickel binding C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein uL15/eL18
Tryptophan synthase beta chain-like PALP
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Methyl-coenzyme M reductase I subunit gamma
Methanogenesis regulatory protein FilR1 middle
Hypoxanthine/guanine phosphoribosyltransferase
DNA mismatch repair proteins mutS family
Helix-hairpin-helix DNA-binding motif class 1
Tetrahydromethanopterin S-methyltransferase subunit E
Alpha-D-phosphohexomutase alpha/beta/alpha
Nascent polypeptide-associated complex protein
Putative cytidyltransferase-related C-terminal region
Formylmethanofuran--tetrahydromethanopterin formyltransferase-like protein
Ketoisovalerate oxidoreductase subunit VorB
Major facilitator superfamily (MFS) profile
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE
Small ribosomal subunit protein uS15 N-terminal
Tetrahydromethanopterin S-methyltransferase subunit H
F420-non-reducing hydrogenase iron-sulfur subunit D
Survival protein SurE-like phosphatase/nucleotidase
5,10-methenyltetrahydromethanopterin hydrogenase
Molybdopterin cofactor biosynthesis C (MoaC)
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Bacterial transcription activator effector binding
Large ribosomal subunit protein uL10-like insertion
Formylmethanofuran dehydrogenase subunit E
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ketoisovalerate oxidoreductase subunit VorC
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Tetrahydromethanopterin S-methyltransferase subunit D
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Nitrogenase molybdenum-iron protein beta chain
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Bacterial bifunctional deaminase-reductase C-terminal
H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit B
Glutamate synthase alpha subunit C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Solute-binding protein family 3/N-terminal
Glycosyltransferase family 28 N-terminal
Methyl-coenzyme M reductase I operon protein D
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Tetrahydromethanopterin S-methyltransferase subunit F
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Putative ABC transporter ATP-binding protein MTBMA_c05830
5,10-methylenetetrahydromethanopterin reductase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Small zinc finger protein HVO-2753-like zinc-binding pocket
Damage-control phosphatase ARMT1-like metal-binding
ATPsynthase alpha/beta subunit N-terminal extension
Methyl-coenzyme M reductase II subunit alpha
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Schiff-base intermediate with acetaldehyde
Type I restriction modification DNA specificity
Inosine monophosphate cyclohydrolase-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Transcription factor CBF/NF-Y/archaeal histone
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Tetrahydromethanopterin S-methyltransferase subunit G
Spo11/DNA topoisomerase VI subunit A N-terminal
Large ribosomal subunit protein uL2 C-terminal
Sugar fermentation stimulation protein C-terminal
Indolepyruvate oxidoreductase subunit IorA
RNA polymerase subunit H/Rpb5 C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
N6 adenine-specific DNA methyltransferase N-terminal
7 X 13 AA repeats of [GW]-X-X-M-X-X-G-X-[IL]-X-[IV]-X-G
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C
6-hydroxymethylpterin diphosphokinase MptE-like
Methyl-coenzyme M reductase II subunit beta
Non-canonical purine NTP phosphatase/PRRC1
Ribose-phosphate pyrophosphokinase N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aspartate/homoserine dehydrogenase NAD-binding
Methyl-coenzyme M reductase I operon protein C
Increases nucleophilicity of active site Cys
Nitrogenase molybdenum-iron protein alpha chain
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Restriction system protein Mrr-like N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Tetrahydromethanopterin S-methyltransferase subunit B
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Nitrogen fixation nifHD region GlnB-like protein 2
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Cytochrome C biogenesis protein transmembrane
H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit A
Methenyltetrahydromethanopterin cyclohydrolase
Phosphoribosylformylglycinamidine synthase subunit PurL
DNA-directed RNA polymerase RBP11-like dimerisation
Schiff-base intermediate with dihydroxyacetone-P
Geranylgeranylglyceryl phosphate synthase
Schiff-base intermediate with D-ribose 5-phosphate
DNA-directed RNA polymerase subunit 2 hybrid-binding
Na+/H+ antiporter MnhB subunit-related protein
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Plays an important role in substrate specificity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
6-phosphogluconate dehydrogenase NADP-binding
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase C-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
No change in cofactor binding. No change in cofactor binding; when associated with K-94.
No change in cofactor binding; when associated with K-35.
Tetrahydromethanopterin S-methyltransferase subunit A 1
Removed in mature form; by autocatalysis
Cysteine sulfenic acid (-SOH) intermediate
Methyl-coenzyme M reductase I subunit beta
Methyl-coenzyme M reductase I subunit alpha
Sodium/calcium exchanger membrane region
Ribosomal RNA adenine methylase transferase N-terminal
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Nitrogen fixation nifHD region GlnB-like protein 1
Dihydroneopterin aldolase MtpD C-terminal
Aminoacyl-tRNA synthetase class II (G/ P/ S/T)
Proliferating cell nuclear antigen PCNA N-terminal
DNA polymerase alpha/delta/epsilon subunit B
Methyl-coenzyme M reductase II subunit gamma
Short chain isoprenyl diphosphate synthase
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Pyridoxamine 5'-phosphate oxidase putative
Pyruvate phosphate dikinase AMP/ATP-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
TATA box binding protein associated factor (TAF) histone-like fold
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Translation elongation factor IF5A C-terminal
Pseudouridine synthase I TruA alpha/beta
Peptidase A24A-predicted C-terminal archaea
Prepilin type IV endopeptidase peptidase
Peptide methionine sulphoxide reductase MsrA
Resistance to mupirocin (pseudomonic acid A).
F420-dependent methylenetetrahydromethanopterin dehydrogenase
Indolepyruvate oxidoreductase subunit IorB
7 X 13 AA repeats of [GW]-X-X-M-X-X-G-X-I-X-[IV]-X-G
Molybdenum-containing formylmethanofuran dehydrogenase 1 subunit C
Alanyl-transfer RNA synthetases family profile
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Small ribosomal subunit protein uS4 N-terminal
Tetrahydromethanopterin S-methyltransferase subunit C
Could be important to modulate the pK values of the two catalytic cysteine residues