Transcription regulator AsnC/Lrp ligand binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NADH:ubiquinone oxidoreductase 30kDa subunit
Sodium/calcium exchanger membrane region
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Sodium symporter small subunit predicted
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Non-canonical purine NTP phosphatase/PRRC1
Bacterioopsin transcriptional activator GAF and HTH associated
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Tryptophan synthase beta chain-like PALP
NIF system FeS cluster assembly NifU N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Polymerase/histidinol phosphatase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Plays an important role in substrate specificity
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Major facilitator superfamily (MFS) profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Polysaccharide biosynthesis protein C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL6 alpha-beta
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
tRNA nucleotidyltransferase substrate binding
Na+/H+ antiporter MnhB subunit-related protein
Pyruvate phosphate dikinase AMP/ATP-binding
Large ribosomal subunit protein uL10-like insertion
Type IV secretion system coupling protein TraD DNA-binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Translation elongation factor IF5A C-terminal
Moybdenum cofactor oxidoreductase dimerisation
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome C biogenesis protein transmembrane
UDP-glucose/GDP-mannose dehydrogenase C-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
DNA mismatch repair proteins mutS family
Aldehyde ferredoxin oxidoreductase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Transcription factor NikR nickel binding C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Small ribosomal subunit protein uS4 N-terminal
Pseudouridine synthase I TruA alpha/beta
Alanyl-transfer RNA synthetases family profile
Inner membrane protein YgaP-like transmembrane
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyridoxamine 5'-phosphate oxidase putative
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Phosphoadenosine phosphosulphate reductase
YbaK/aminoacyl-tRNA synthetase-associated
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
6-phosphogluconate dehydrogenase C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Succinate dehydogenase/fumarate reductase N-terminal
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aminoacyl-transfer RNA synthetases class-II family profile
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Involved in ionization of N3 of dUMP, leading to its activation
SUF system FeS cluster assembly SufBD N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Glycine cleavage T-protein C-terminal barrel
Large ribosomal subunit protein uL2 C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
FAD-dependent oxidoreductase 2 FAD binding
Bacterial type II secretion system protein E
Type II restriction enzyme and methyltransferase RM.Eco57I-like
DR2241 4Fe-4S iron-sulfur cluster binding
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Schiff-base intermediate with D-ribose 5-phosphate
Glycosyl transferase family 3 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
NIF system FeS cluster assembly NifU C-terminal
Large ribosomal subunit protein uL15/eL18
Nucleolar GTP-binding protein 1 Rossman-fold
Inosine monophosphate cyclohydrolase-like
NADH-rubredoxin oxidoreductase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Peptide methionine sulphoxide reductase MsrA
Transcription factor CBF/NF-Y/archaeal histone
DNA polymerase II large subunit DP2 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Methanogenesis regulatory protein FilR1 middle
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-77)
Heme-copper oxidase subunit III family profile
DNA polymerase alpha/delta/epsilon subunit B
Cytochrome b/b6 C-terminal region profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Archaeal glycosylation protein B peripheral
D-galactarate/Altronate dehydratase C-terminal
Small ribosomal subunit protein eS4 N-terminal
Small ribosomal subunit protein eS4 central region
Molybdopterin cofactor biosynthesis C (MoaC)
Cytochrome b561 bacterial/Ni-hydrogenase
Alpha-L-glutamate ligase-related protein ATP-grasp
Schiff-base intermediate with dihydroxyacetone-P
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Ribosomal RNA adenine methylase transferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Electron transfer via tryptophanyl radical
Removed in mature form; by autocatalysis
Schiff-base intermediate with acetaldehyde
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Peptidase S9 prolyl oligopeptidase catalytic
Siroheme decarboxylase AsnC-like ligand binding
Anthranilate synthase component I N-terminal
MPBQ/MBSQ family SAM-binding methyltransferase profile
Probable transposase IS891/IS1136/IS1341
Dihydroneopterin aldolase MtpD C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Actinobacteria/chloroflexi VLRF1 release factor
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Spo11/DNA topoisomerase VI subunit A N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Cytochrome b/b6 N-terminal region profile
Phosphotransferase system enzyme I N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
DNA-directed RNA polymerase RBP11-like dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
DNA recombination and repair protein Rad51-like C-terminal
Menaquinone biosynthesis protein MenD middle
Small zinc finger protein HVO-2753-like zinc-binding pocket
Tetrahydrodipicolinate-N-succinyltransferase chain A
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Proton donor; for OHCU decarboxylase activity
Quinolinate phosphoribosyl transferase C-terminal
Small ribosomal subunit protein uS15 N-terminal
Signal recognition particle SRP54 helical bundle
Aspartate/homoserine dehydrogenase NAD-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Survival protein SurE-like phosphatase/nucleotidase
rRNA small subunit methyltransferase F RNA-binding PUA-like
ABC transporter substrate-binding protein PnrA-like
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile