Polymerase/histidinol phosphatase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Sodium/calcium exchanger membrane region
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Flagellar motor switch protein FliN-like C-terminal
CRISPR-associated protein Cas6 C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
RsbT co-antagonist protein RsbRD N-terminal
Flagellar basal-body/hook protein C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Putative regulatory protein FmdB Zinc ribbon
Flagellar basal body rod protein N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Major facilitator superfamily (MFS) profile
Bacterial type II secretion system protein E
Pyruvate phosphate dikinase AMP/ATP-binding
Anthranilate synthase component I N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Prokaryotic-type class I peptide chain release factors
Putative glycogen debranching enzyme N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Tryptophan synthase beta chain-like PALP
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
DNA replication/recombination mediator RecO N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Carbamoyl-phosphate synthase small subunit N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein uL2 C-terminal
TonB-dependent receptor-like beta-barrel
CobB/CobQ-like glutamine amidotransferase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Polysaccharide biosynthesis protein C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycosyltransferase subfamily 4-like N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-222); in linked form
Interchain (with Cys-53); in linked form
Pseudouridine synthase I TruA alpha/beta
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Curli production assembly/transport component CsgF
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Siroheme decarboxylase AsnC-like ligand binding
DnaJ homologue subfamily C member 28 conserved
Schiff-base intermediate with acetaldehyde
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Release factor glutamine methyltransferase N-terminal
Magnesium transporter MgtE intracellular
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Cation-transporting P-type ATPase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Translation elongation factor P/YeiP central
Transcription factor NikR nickel binding C-terminal
Flagellar Assembly Protein A N-terminal region
Mannose-6-phosphate isomerase type II C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
RNA binding; important for wobble base 34 recognition
Dinitrogenase iron-molybdenum cofactor biosynthesis
Small ribosomal subunit protein uS4 N-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Organic solvent tolerance-like N-terminal
Methylene-tetrahydrofolate reductase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Penicillin-binding protein transpeptidase
Pyruvate/ketoisovalerate oxidoreductase catalytic
Damage-control phosphatase ARMT1-like metal-binding
Ribosomal RNA adenine methylase transferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Trigger factor ribosome-binding bacterial
Alanyl-transfer RNA synthetases family profile
Manganese/iron superoxide dismutase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar hook-length control protein-like C-terminal
Phosphoribosylformylglycinamidine synthase linker
tRNA pseudouridylate synthase B C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA mismatch repair proteins mutS family
Schiff-base intermediate with substrate; via pyruvic acid
Formylmethanofuran dehydrogenase subunit E
Membrane insertase YidC/Oxa/ALB C-terminal
Glycoside hydrolase family 57 N-terminal
Polysaccharide chain length determinant N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Reversibly protonated during proton transport
Thiamine pyrophosphate enzyme TPP-binding
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
S-adenosylmethionine-dependent methyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Exonuclease VII large subunit C-terminal
Important for interaction with partner proteins
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyl transferase family 3 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL6 alpha-beta
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Transposase IS116/IS110/IS902 C-terminal
Haem-binding uptake Tiki superfamily ChaN
N6 adenine-specific DNA methyltransferase N-terminal
Membrane fusion protein biotin-lipoyl like
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Gamma-glutamylcyclotransferase AIG2-like
Homocysteine biosynthesis enzyme sulfur-incorporation
Cytochrome b561 bacterial/Ni-hydrogenase
O-(3'-phospho-DNA)-tyrosine intermediate
NIF system FeS cluster assembly NifU C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
RNA 2-O ribose methyltransferase substrate binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Plays an important role in substrate specificity
Type I restriction modification DNA specificity
Helix-hairpin-helix DNA-binding motif class 1
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Positions MEP for the nucleophilic attack
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Transcription regulator AsnC/Lrp ligand binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Outer membrane lipoprotein BamD-like domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Essential for prephenate dehydratase activity
Prepilin type IV endopeptidase peptidase
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
SMODS-associated and fused to various effectors
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Formamidopyrimidine-DNA glycosylase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Could be important to modulate the pK values of the two catalytic cysteine residues