Gamma-glutamylcyclotransferase AIG2-like
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
RNA polymerase sigma factor 70 region 4 type 2
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Major facilitator superfamily (MFS) profile
Glucosamine/galactosamine-6-phosphate isomerase
Translation elongation factor P/YeiP central
Solute-binding protein family 3/N-terminal
Peptidase C39-like domain-containing protein
Phosphocysteine intermediate; for EIIB activity
CD-NTase-associated protein 12/Pycsar effector protein TIR
RNA 2-O ribose methyltransferase substrate binding
Butirosin biosynthesis protein H N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aminoacyl-transfer RNA synthetases class-II family profile
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Transcriptional regulator SgrR N-terminal HTH
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Polysaccharide biosynthesis protein C-terminal
Large ribosomal subunit protein bL12 C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Pyrimidine nucleoside phosphorylase C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycoside hydrolase family 42 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Penicillin-binding protein transpeptidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
ABC transporter substrate-binding protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
ABC-type glycine betaine transport system substrate-binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Plays an important role in substrate specificity
Thymidylate synthase/dCMP hydroxymethylase
Flagellar motor switch protein FliN-like C-terminal
M protein trans-acting positive regulator (MGA) HTH
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyruvate phosphate dikinase AMP/ATP-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
6-phosphogluconate dehydrogenase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Prepilin type IV endopeptidase peptidase
May play a role in transmitting local conformational changes
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Small ribosomal subunit protein uS4 N-terminal
Threonine/serine exporter-like N-terminal
Membrane fusion protein biotin-lipoyl like
Ferrous iron transport protein B C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Cysteine sulfenic acid (-SOH) intermediate
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Major facilitator superfamily associated
Tryptophan RNA-binding attenuator protein
Fibronectin type-III domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Mandelate racemase/muconate lactonizing enzyme N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
RND efflux pump membrane fusion protein barrel-sandwich
Acyl-CoA dehydrogenase/oxidase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Polymerase/histidinol phosphatase N-terminal
Cell envelope-related transcriptional attenuator
Schiff-base intermediate with substrate; via pyruvic acid
Cytochrome b/b6 C-terminal region profile
Bacterial transcription activator effector binding
RNA binding; important for wobble base 34 recognition
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Sporulation transcription regulator WhiA N-terminal
WGxxGxxG-CTERM domain-containing protein
Polysaccharide chain length determinant N-terminal
Protein-PII uridylyltransferase N-terminal
Tryptophan synthase beta chain-like PALP
Phosphotransferase system enzyme I N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Diacylglycerol glucosyltransferase N-terminal
Signal recognition particle SRP54 helical bundle
Ionotropic glutamate receptor C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Lysidine-tRNA(Ile) synthetase C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
DnaJ homologue subfamily C member 28 conserved
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycosyl transferase family 28 C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Phosphomannose isomerase type I catalytic
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Important for beta-aspartyl-AMP intermediate formation
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Carbamoyl-phosphate synthase small subunit N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
ABC transporter substrate-binding protein PnrA-like
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Anthranilate synthase component I N-terminal
ABC-type uncharacterised transport system
S-adenosyl-L-homocysteine hydrolase NAD binding
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Bacterial toxin 44 domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Copper amine oxidase-like N-terminal domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Schiff-base intermediate with acetaldehyde
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar Assembly Protein A N-terminal region
Interaction with polymerase core subunit RpoC
Carbohydrate-binding/sugar hydrolysis domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
S-adenosylmethionine-dependent methyltransferase
Magnesium transporter MgtE intracellular
Helix-hairpin-helix DNA-binding motif class 1
DNA-directed DNA polymerase family A palm
O-(5'-phospho-DNA)-tyrosine intermediate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
General stress protein FMN-binding split barrel
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome b/b6 N-terminal region profile
Sporulation stage II protein D amidase enhancer LytB N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Cation-transporting P-type ATPase N-terminal
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein bL12 oligomerization
Flagellar hook-length control protein-like C-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Periplasmic binding protein domain-containing protein
Bacterial type II secretion system protein E
Pseudouridine synthase I TruA alpha/beta
DNA mismatch repair proteins mutS family
Cell wall-active antibiotics response LiaF-like C-terminal
Next to BRCA1 central domain-containing protein
Glycosyltransferase family 28 N-terminal
Heme-copper oxidase subunit III family profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Inosine/uridine-preferring nucleoside hydrolase
Phosphoribosylformylglycinamidine synthase linker
Peptide methionine sulphoxide reductase MsrA
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Schiff-base intermediate with D-ribose 5-phosphate
Large ribosomal subunit protein uL2 C-terminal
Thiamin pyrophosphokinase thiamin-binding
Glycosyl transferase family 3 N-terminal
NIF system FeS cluster assembly NifU C-terminal
Fibronectin type III domain-containing protein
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Ribonucleotide reductase large subunit C-terminal
Chromosomal replication initiator DnaA C-terminal
Protein O-mannosyl-transferase C-terminal four TM
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Saccharopine dehydrogenase-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Dipicolinate synthase subunit A N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Periplasmic copper-binding protein NosD beta helix
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
DNA replication/recombination mediator RecO N-terminal
Polynucleotide kinase-phosphatase ligase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Flagellar assembly protein FliH/Type III secretion system HrpE
Involved in allosteric activation by GTP
Resolvase/invertase-type recombinase catalytic
Type III secretion system flagellar brake protein YcgR PilZN
Shikimate dehydrogenase substrate binding N-terminal
Essential for prephenate dehydratase activity
Bacteriophage lambda Replication protein O N-terminal
Polysaccharide biosynthesis protein CapD-like
Important for interaction with partner proteins
Alanyl-transfer RNA synthetases family profile
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Fe/B12 periplasmic-binding domain-containing protein
Putative amidase domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Phage terminase large subunit N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glycoside hydrolase family 31 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Superoxide dismutase copper/zinc binding
Putative aromatic acid exporter C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Sporulation stage IV protein A C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Beta-1,3-glucanase N-terminal domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cytochrome C biogenesis protein transmembrane
Mannose-6-phosphate isomerase type II C-terminal
SbsC C-terminal domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL15/eL18
Exonuclease VII large subunit C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
NIF system FeS cluster assembly NifU N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Reversibly protonated during proton transport
Sodium/calcium exchanger membrane region