Glycosyltransferase subfamily 4-like N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Saccharopine dehydrogenase-like C-terminal
Sugar fermentation stimulation protein C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Tryptophan synthase beta chain-like PALP
Aminoacyl-transfer RNA synthetases class-II family profile
Major facilitator superfamily (MFS) profile
Glycoside hydrolase family 31 N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
CRISPR system ring nuclease SSO1393-like
FAD-dependent oxidoreductase 2 FAD binding
Pyruvate phosphate dikinase AMP/ATP-binding
Sodium/calcium exchanger membrane region
Polysaccharide biosynthesis protein C-terminal
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
CRISPR-associated protein Cas6 C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Translation elongation factor IF5A C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Interchain (with Cys-208); in linked form
Interchain (with Cys-49); in linked form
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Alpha,alpha-trehalose-phosphate synthase
Bifunctional trehalose-6-phosphate synthase/phosphatase
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Non-canonical purine NTP phosphatase/PRRC1
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transcription factor NikR nickel binding C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
S-adenosyl-L-homocysteine hydrolase NAD binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
CRISPR-associated protein Cas7/Cst2/DevR
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Periplasmic copper-binding protein NosD beta helix
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Glycoside hydrolase family 57 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Schiff-base intermediate with D-ribose 5-phosphate
Cytochrome c-552/DMSO reductase-like haem-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Survival protein SurE-like phosphatase/nucleotidase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL6 alpha-beta
tRNA nucleotidyltransferase substrate binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Resolvase/invertase-type recombinase catalytic
Myo-inositol-1-phosphate synthase GAPDH-like
Large ribosomal subunit protein uL2 C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
NADH:ubiquinone oxidoreductase-like 20kDa subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
SUF system FeS cluster assembly SufBD N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Peptidase M1 membrane alanine aminopeptidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
CRISPR locus-related putative DNA-binding protein Csa3
Large ribosomal subunit protein uL15/eL18
Damage-control phosphatase ARMT1-like metal-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA-directed RNA polymerase M/15kDa subunit
Aldehyde ferredoxin oxidoreductase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Signal recognition particle SRP54 helical bundle
Large ribosomal subunit protein uL11 C-terminal
Transcription regulator AsnC/Lrp ligand binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alpha-D-phosphohexomutase alpha/beta/alpha
Nitrite/Sulfite reductase ferredoxin-like
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cytochrome b/b6 N-terminal region profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Alanyl-transfer RNA synthetases family profile
6-hydroxymethylpterin diphosphokinase MptE-like
Removed in mature form; by autocatalysis
Small ribosomal subunit protein uS15 N-terminal
ABC transporter substrate-binding protein PnrA-like
Peptidase S9 prolyl oligopeptidase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Involved in ionization of N3 of dUMP, leading to its activation
Anthranilate synthase component I N-terminal
Schiff-base intermediate with acetaldehyde
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Pseudouridine synthase I TruA alpha/beta
Small zinc finger protein HVO-2753-like zinc-binding pocket
Bacterial bifunctional deaminase-reductase C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Spo11/DNA topoisomerase VI subunit A N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Phosphoribosylformylglycinamidine synthase linker
Loss of FBP aldolase activity; when associated with F-146.
Schiff-base intermediate with dihydroxyacetone-P
The catalytic activity is at least 3-fold lower than for the wild-type. Loss of FBP aldolase activity; when associated with E-144.
Large ribosomal subunit protein uL10-like insertion
ATPsynthase alpha/beta subunit N-terminal extension
SAM-dependent methyltransferase TRM5/TYW2-type
Gfo/Idh/MocA-like oxidoreductase N-terminal
Methionyl-tRNA synthetase anticodon-binding
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange