DNA replication/recombination mediator RecO N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Small ribosomal subunit protein uS4 N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Cysteine sulfenic acid (-SOH) intermediate
Membrane fusion protein biotin-lipoyl like
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Glycosyltransferase family 28 N-terminal
Major facilitator superfamily (MFS) profile
Thiol:disulfide interchange protein DsbA
Thiol:disulfide interchange protein DsbD N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Schiff-base intermediate with substrate; via pyruvic acid
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Large ribosomal subunit protein uL6 alpha-beta
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aspartate/homoserine dehydrogenase NAD-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
TonB-dependent receptor-like beta-barrel
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Putative regulatory protein FmdB Zinc ribbon
Anthranilate synthase component I N-terminal
Flagellar motor switch protein FliN-like C-terminal
Interaction with polymerase core subunit RpoC
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glucan biosynthesis periplasmic MdoG C-terminal
Polymerase/histidinol phosphatase N-terminal
Bacterial type II secretion system protein E
Peptide methionine sulphoxide reductase MsrA
Acyl-CoA dehydrogenase/oxidase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Important for substrate binding and specificity
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
RND efflux pump membrane fusion protein barrel-sandwich
Prokaryotic-type class I peptide chain release factors
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
DNA mismatch repair proteins mutS family
Inosine/uridine-preferring nucleoside hydrolase
NAD(P) transhydrogenase alpha subunit C-terminal
Prepilin type IV endopeptidase peptidase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Aconitase A/isopropylmalate dehydratase small subunit swivel
Peptidase M1 membrane alanine aminopeptidase
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Peptidase S9 prolyl oligopeptidase catalytic
Important for interaction with partner proteins
Putative adhesin domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Polysaccharide biosynthesis protein CapD-like
Resolvase/invertase-type recombinase catalytic
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Glutathionylspermidine synthase pre-ATP-grasp-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Proline utilization A proline dehydrogenase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Glycine cleavage T-protein C-terminal barrel
RNA 2-O ribose methyltransferase substrate binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Moves into active site upon enzyme activation, plays a role in electron transfer
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Mandelate racemase/muconate lactonizing enzyme C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Translation elongation factor P/YeiP central
Integral membrane protein YccS N-terminal
Glycosyl transferase family 3 N-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Heat-inducible transcription repressor HrcA C-terminal
Tryptophan synthase beta chain-like PALP
RNA polymerase sigma factor 70 region 4 type 2
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
YbaK/aminoacyl-tRNA synthetase-associated
Pyruvate dehydrogenase E1 component middle
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Cyclophilin-like domain-containing protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
N6 adenine-specific DNA methyltransferase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Type I restriction modification DNA specificity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Release factor glutamine methyltransferase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Key residue in conferring substrate specificity for N-acetyl-L-ornithine versus N-succinyl-L-ornithine
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Chromosomal replication initiator protein DnaA
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
O-(5'-phospho-DNA)-tyrosine intermediate
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glycoside hydrolase family 42 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyrroline-5-carboxylate reductase dimerisation
Helix-hairpin-helix DNA-binding motif class 1
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Outer-membrane lipoprotein carrier protein
Sodium/calcium exchanger membrane region
Outer membrane protein assembly factor BamB
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Protein involved in meta-pathway of phenol degradation
N-end rule aminoacyl transferase C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Outer membrane protein assembly factor BamD
Lactate utilization protein B C-terminal
Outer membrane protein assembly factor BamA
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Mannose-6-phosphate isomerase type II C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
tRNA pseudouridylate synthase B C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glycosyl transferase family 28 C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Solute-binding protein family 3/N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Endolytic peptidoglycan transglycosylase RlpA
6-phosphogluconate dehydrogenase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Disulphide bond isomerase DsbC/G N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
High potential iron-sulfur proteins family profile
Outer membrane protein beta-barrel domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Phosphotransferase system enzyme I N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Pseudouridine synthase I TruA alpha/beta
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Important for beta-aspartyl-AMP intermediate formation
Phosphatidic acid phosphatase type 2/haloperoxidase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Ysc84 actin-binding domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cytochrome c-type biogenesis protein CcmF C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Positions MEP for the nucleophilic attack
Trigger factor ribosome-binding bacterial
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Essential for prephenate dehydratase activity
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Lysidine-tRNA(Ile) synthetase C-terminal
Haemophore haem-binding domain-containing protein
PHA accumulation regulator DNA-binding N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Plays an important role in substrate specificity
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Reversibly protonated during proton transport
Required for zinc-mediated homotetramerization and catalytic activity
Ribose-phosphate pyrophosphokinase N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Arginine decarboxylase C-terminal helical
Proton acceptor; for glutaminase activity
Ribonucleotide reductase large subunit C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Lytic transglycosylase superhelical linker
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
NIF system FeS cluster assembly NifU C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Large ribosomal subunit protein uL15/eL18
NADH:ubiquinone oxidoreductase 30kDa subunit
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glucosamine/galactosamine-6-phosphate isomerase
Aminoacyl-tRNA synthetase class I anticodon-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Transferrin-binding protein B C-lobe/N-lobe beta barrel
Transferrin-binding protein B C-lobe/N-lobe beta barrel domain-containing protein
Alpha galactosidase C-terminal beta sandwich
Chromosomal replication initiator DnaA C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation