Glucose-methanol-choline oxidoreductase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pseudouridine synthase I TruA alpha/beta
Flavocytochrome c sulphide dehydrogenase flavin-binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cytochrome c-552/4 domain-containing protein
Type 4 fimbrial biogenesis protein PilX N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Lipoprotein YgdI/YgdR-like SH3-like domain-containing protein
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Exonuclease VII large subunit C-terminal
Acetylserotonin O-methyltransferase dimerisation
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
SUF system FeS cluster assembly SufBD N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Glycosyltransferase subfamily 4-like N-terminal
ABC-type uncharacterised transport system
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Penicillin-binding protein transpeptidase
N6 adenine-specific DNA methyltransferase N-terminal
Phosphoadenosine phosphosulphate reductase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Phosphotransferase system enzyme I N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
TonB-dependent receptor-like beta-barrel
Aminoacyl-transfer RNA synthetases class-II family profile
L,D-transpeptidase catalytic domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Water stress and hypersensitive response
Solute-binding protein family 3/N-terminal
Bacterial type II secretion system protein E
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Ribulose bisphosphate carboxylase small subunit
Dinitrogenase iron-molybdenum cofactor biosynthesis
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Moybdenum cofactor oxidoreductase dimerisation
Magnesium chelatase subunit H N-terminal
Sodium/calcium exchanger membrane region
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NADH:ubiquinone oxidoreductase 30kDa subunit
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
O-(5'-phospho-DNA)-tyrosine intermediate
Prokaryotic-type class I peptide chain release factors
Rap1a immunity protein domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
6-phosphogluconate dehydrogenase C-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Outer membrane lipoprotein-sorting protein
Transcription factor NikR nickel binding C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
CagE TrbE VirB component of type IV transporter system central
Putative beta-barrel assembly-enhancing protease
Gly-cisPro motif, important for rejection of L-amino acids
Ribonucleotide reductase large subunit C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Cytochrome b561 bacterial/Ni-hydrogenase
Lysidine-tRNA(Ile) synthetase C-terminal
Tryptophan synthase beta chain-like PALP
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Outer membrane protein assembly factor BamD
Glycoside hydrolase family 57 N-terminal
F420-non-reducing hydrogenase iron-sulfur subunit D
Molybdopterin cofactor biosynthesis C (MoaC)
RlpA-like protein double-psi beta-barrel
Electron transfer via tryptophanyl radical
Large ribosomal subunit protein uL6 alpha-beta
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Interaction with polymerase core subunit RpoC
S-adenosylmethionine-dependent methyltransferase
RNA binding; important for wobble base 34 recognition
Magnesium-protoporphyrin IX methyltransferase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
S-adenosyl-L-homocysteine hydrolase NAD binding
Ysc84 actin-binding domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Alanyl-transfer RNA synthetases family profile
DNA polymerase III delta subunit C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Could be important to modulate the pK values of the two catalytic cysteine residues
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Na+/H+ antiporter MnhB subunit-related protein
PHA accumulation regulator DNA-binding N-terminal
SGNH hydrolase-type esterase domain-containing protein
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
CobB/CobQ-like glutamine amidotransferase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Tetrahydrodipicolinate-N-succinyltransferase chain A
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
RND efflux pump membrane fusion protein barrel-sandwich
Nitrite/Sulfite reductase ferredoxin-like
Major facilitator superfamily (MFS) profile
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Important for substrate binding and specificity
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Curlin associated repeat-containing protein
Large ribosomal subunit protein uL2 C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Polymerase/histidinol phosphatase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Thymidylate synthase/dCMP hydroxymethylase
Phosphoethanolamine transferase N-terminal
Alginate export domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Anthranilate synthase component I N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Type III restriction enzyme C-terminal endonuclease
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
HupH hydrogenase expression protein C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Cation-transporting P-type ATPase N-terminal
BREX system Lon protease-like BrxL N-terminal
Large ribosomal subunit protein uL15/eL18
Polysaccharide chain length determinant N-terminal
Translocation and assembly module subunit TamA
Glucosamine/galactosamine-6-phosphate isomerase
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Increases nucleophilicity of active site Cys
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Thiol:disulfide interchange protein DsbD
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
N-end rule aminoacyl transferase C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Ribose-phosphate pyrophosphokinase N-terminal
Prepilin type IV endopeptidase peptidase
Membrane fusion protein biotin-lipoyl like
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Outer membrane protein beta-barrel domain-containing protein
Microcin J25-processing protein McjB C-terminal
Signal transduction histidine kinase dimerisation/phosphoacceptor
Inner membrane protein YgaP-like transmembrane
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Glycosyl transferase family 3 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Important for autoinhibition of adenylyltransferase activity
Flagellar assembly protein FliH/Type III secretion system HrpE
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Positions MEP for the nucleophilic attack
Putative regulatory protein FmdB Zinc ribbon
Damage-control phosphatase ARMT1-like metal-binding
Could play a key role in the communication between the regulatory and the substrate sites
Translation elongation factor P/YeiP central
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Lytic transglycosylase superhelical linker
Arginine decarboxylase C-terminal helical
CRISPR-associated protein Cas6 C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Glycine zipper domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Pyruvate/ketoisovalerate oxidoreductase catalytic
Essential for prephenate dehydratase activity
Ribosomal RNA adenine methylase transferase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Survival protein SurE-like phosphatase/nucleotidase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycine cleavage T-protein C-terminal barrel
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
High potential iron-sulfur proteins family profile
Membrane insertase YidC/Oxa/ALB C-terminal
Plays an important role in substrate specificity
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Sodium symporter small subunit predicted
Aminoacyl-tRNA synthetase class I anticodon-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Photosynthetic reaction centre H subunit N-terminal
Photosynthetic reaction center cytochrome c subunit
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Disulphide bond isomerase DsbC/G N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Transposase IS116/IS110/IS902 C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA-directed DNA polymerase family A palm
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
ATP-grasp fold succinyl-CoA synthetase-type
Glycoside hydrolase family 31 N-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
P pilus assembly protein, chaperone PapD
Outer-membrane lipoprotein carrier protein
DnaJ homologue subfamily C member 28 conserved
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
DNA replication/recombination mediator RecO N-terminal
Type II secretion system protein GspG C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Type I restriction modification DNA specificity
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Clan AA aspartic protease, TIGR02281 family
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Reversibly protonated during proton transport
ATPsynthase alpha/beta subunit N-terminal extension
Carboxypeptidase regulatory-like domain-containing protein