Tryptophan synthase beta chain-like PALP
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Required for zinc-mediated homotetramerization and catalytic activity
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Sodium/calcium exchanger membrane region
Major facilitator superfamily (MFS) profile
Rap1a immunity protein domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
RND efflux pump membrane fusion protein barrel-sandwich
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Sodium symporter small subunit predicted
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Large ribosomal subunit protein uL15/eL18
Cytochrome b561 bacterial/Ni-hydrogenase
Cysteine sulfenic acid (-SOH) intermediate
Gamma-butyrobetaine hydroxylase-like N-terminal
Twin-arginine translocation pathway signal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Resolvase/invertase-type recombinase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Prokaryotic-type class I peptide chain release factors
Aminoacyl-transfer RNA synthetases class-II family profile
Dinitrogenase iron-molybdenum cofactor N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Ribosomal RNA adenine methylase transferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Outer membrane protein assembly factor BamA
Glycosyl transferase family 3 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Outer membrane lipoprotein-sorting protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DNA mismatch repair proteins mutS family
Peptidase M1 membrane alanine aminopeptidase
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
O-(3'-phospho-DNA)-tyrosine intermediate
Type IV secretion system coupling protein TraD DNA-binding
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Prepilin type IV endopeptidase peptidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Membrane insertase YidC/Oxa/ALB C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-213); in linked form
Interchain (with Cys-53); in linked form
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Penicillin-binding protein transpeptidase
Polysaccharide chain length determinant N-terminal
Glycine-zipper-containing OmpA-like membrane
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Inner membrane protein YgaP-like transmembrane
Quercetin 2,3-dioxygenase C-terminal cupin
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Translation elongation factor P/YeiP central
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
TonB-dependent receptor-like beta-barrel
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Bacterial type II secretion system protein E
Gp5/Type VI secretion system Vgr protein OB-fold
DNA replication/recombination mediator RecO N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
DNA-directed DNA polymerase family A palm
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Nitrite/Sulfite reductase ferredoxin-like
ATP-dependent DNA helicase RecG C-terminal
Anthranilate synthase component I N-terminal
CD-NTase associated protein 4-like DNA endonuclease
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Alginate export domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Important for beta-aspartyl-AMP intermediate formation
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Glycine cleavage T-protein C-terminal barrel
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
High potential iron-sulfur proteins family profile
Mechanosensitive ion channel inner membrane
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphate ABC transporter substrate-binding protein
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Acetylserotonin O-methyltransferase dimerisation
Na+/H+ antiporter MnhB subunit-related protein
Peptide methionine sulphoxide reductase MsrA
NAD(P) transhydrogenase alpha subunit C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Essential for prephenate dehydratase activity
RNA polymerase sigma factor 70 region 4 type 2
UDP N-acetylglucosamine O-acyltransferase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Phosphocysteine intermediate; for EIIB activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
Plays an important role in substrate specificity
ABC-type uncharacterised transport system
Glycogen debranching enzyme bacterial and archaeal type N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Protein kinase G tetratricopeptide repeat containing
Right handed beta helix domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Transposase IS116/IS110/IS902 C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Histidine-specific methyltransferase SAM-dependent
Electron transfer via tryptophanyl radical
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL2 C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Urease accessory protein UreH-like transmembrane
HicB-like antitoxin of toxin-antitoxin system
Putative regulatory protein FmdB Zinc ribbon
N-end rule aminoacyl transferase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Type II secretion system protein GspC N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Type I restriction enzyme R protein N-terminal
Bacteriophage tail tape measure C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Lysozyme inhibitor LprI N-terminal domain-containing protein
Disulphide bond isomerase DsbC/G N-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Ysc84 actin-binding domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Type I restriction modification DNA specificity
DNA polymerase III subunit delta C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
Reversibly protonated during proton transport
Glycoside hydrolase family 57 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Carbamoyl-phosphate synthase small subunit N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
6-phosphogluconate dehydrogenase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
HupH hydrogenase expression protein C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Polymerase/histidinol phosphatase N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Periplasmic nitrate reductase, electron transfer subunit
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Important for autoinhibition of adenylyltransferase activity
Could be important to modulate the pK values of the two catalytic cysteine residues
Survival protein SurE-like phosphatase/nucleotidase
Interaction with polymerase core subunit RpoC
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Type III restriction enzyme C-terminal endonuclease
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glucosamine/galactosamine-6-phosphate isomerase
Anaphase-promoting complex subunit 4-like WD40
Flagellar hook-length control protein-like C-terminal
Outer membrane protein beta-barrel domain-containing protein
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
ATP synthase F1 complex delta/epsilon subunit N-terminal
Type VI secretion system IcmF C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Threonine/serine exporter-like N-terminal
Membrane fusion protein biotin-lipoyl like
ATPsynthase alpha/beta subunit N-terminal extension
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
PHA accumulation regulator DNA-binding N-terminal
Flagellar motor switch protein FliN-like C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
PEP-CTERM exosortase interaction domain-containing protein
Solute-binding protein family 3/N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
S-adenosylmethionine-dependent methyltransferase
Damage-control phosphatase ARMT1-like metal-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Could play a key role in the communication between the regulatory and the substrate sites
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Mannose-6-phosphate isomerase type II C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Transposase IS204/IS1001/IS1096/IS1165 DDE
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Required for dimer formation and molybdate binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
DNA polymerase III delta subunit C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Water stress and hypersensitive response
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Arginine decarboxylase C-terminal helical
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Ribulose bisphosphate carboxylase small subunit
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pyruvate dehydrogenase E1 component middle
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Peptidase propeptide domain-containing protein
Calcineurin-like phosphoesterase domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Restriction system protein Mrr-like N-terminal
RNA 2-O ribose methyltransferase substrate binding
Important for interaction with partner proteins
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Polysaccharide biosynthesis protein C-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Polysaccharide biosynthesis protein CapD-like
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Helix-hairpin-helix DNA-binding motif class 1
NADH:ubiquinone oxidoreductase chain 4 N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Type II secretion system protein GspG C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Lysidine-tRNA(Ile) synthetase C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Magnesium-protoporphyrin IX methyltransferase C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Positions MEP for the nucleophilic attack
RNA binding; important for wobble base 34 recognition
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Magnesium chelatase subunit H N-terminal
Menaquinone biosynthesis protein MenD middle
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Phosphotransferase system enzyme I N-terminal