Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Type III restriction enzyme C-terminal endonuclease
Phosphatidic acid phosphatase type 2/haloperoxidase
Inner membrane protein YgaP-like transmembrane
Flavocytochrome c sulphide dehydrogenase flavin-binding
Phage conserved hypothetical protein C-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sodium symporter small subunit predicted
Glycosyltransferase subfamily 4-like N-terminal
Tryptophan synthase beta chain-like PALP
Aminoacyl-transfer RNA synthetases class-II family profile
PilC beta-propeller domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Major facilitator superfamily (MFS) profile
Dinitrogenase iron-molybdenum cofactor biosynthesis
Solute-binding protein family 3/N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
HicB-like antitoxin of toxin-antitoxin system
Cysteine sulfenic acid (-SOH) intermediate
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
CobB/CobQ-like glutamine amidotransferase
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Rap1a immunity protein domain-containing protein
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Essential for prephenate dehydratase activity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
ABC-type glycine betaine transport system substrate-binding
RND efflux pump membrane fusion protein barrel-sandwich
Gamma-butyrobetaine hydroxylase-like N-terminal
Photosynthetic reaction centre H subunit N-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Calcineurin-like phosphoesterase domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
RNA binding; important for wobble base 34 recognition
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Polysaccharide chain length determinant N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pseudouridine synthase I TruA alpha/beta
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Cytochrome b561 bacterial/Ni-hydrogenase
Acetylserotonin O-methyltransferase dimerisation
Could be important to modulate the pK values of the two catalytic cysteine residues
FAD-dependent oxidoreductase 2 FAD binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
S-adenosyl-L-homocysteine hydrolase NAD binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Plays an important role in substrate specificity
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
TonB-dependent receptor-like beta-barrel
Nitrogenase molybdenum-iron protein beta chain N-terminal
6-phosphogluconate dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Glycoside hydrolase family 57 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ionotropic glutamate receptor C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Interaction with polymerase core subunit RpoC
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Molybdopterin cofactor biosynthesis C (MoaC)
SUF system FeS cluster assembly SufBD N-terminal
Flagellar motor switch protein FliN-like C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Thiamine pyrophosphate enzyme TPP-binding
Could play a key role in the communication between the regulatory and the substrate sites
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
ABC-type transport auxiliary lipoprotein component
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Sodium/calcium exchanger membrane region
Membrane insertase YidC/Oxa/ALB C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Peptidase C-terminal archaeal/bacterial domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein uL2 C-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Chromosomal replication initiator protein DnaA
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
C-type lysozyme inhibitor domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
ATP synthase F1 complex delta/epsilon subunit N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Survival protein SurE-like phosphatase/nucleotidase
Lysozyme inhibitor LprI N-terminal domain-containing protein
Outer membrane protein assembly factor BamD
Helix-hairpin-helix DNA-binding motif class 1
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
N-end rule aminoacyl transferase C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Lysidine-tRNA(Ile) synthetase C-terminal
Ion-translocating oxidoreductase complex subunit G
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Anthranilate synthase component I N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
PHA accumulation regulator DNA-binding N-terminal
ABC-type uncharacterised transport system
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Bacterial type II secretion system protein E
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
PEP-CTERM protein-sorting domain-containing protein
Peptide methionine sulphoxide reductase MsrA
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
CNP1-like uncharacterized domain-containing protein
DNA mismatch repair proteins mutS family
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Alginate export domain-containing protein
Flagellar hook-length control protein-like C-terminal
DnaJ homologue subfamily C member 28 conserved
Tetrahydrodipicolinate-N-succinyltransferase chain A
Adenosylcobalamin biosynthesis, GlcG-related protein
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Penicillin-binding protein transpeptidase
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Important for interaction with partner proteins
RNA polymerase sigma factor 70 region 4 type 2
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Glycosyl transferase family 3 N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
RNA 2-O ribose methyltransferase substrate binding
DNA-directed DNA polymerase family A palm
Prepilin type IV endopeptidase peptidase
NADH:ubiquinone oxidoreductase 30kDa subunit
Peptidoglycan recognition protein family
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Magnesium-protoporphyrin IX methyltransferase C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Ribulose bisphosphate carboxylase small subunit
N6 adenine-specific DNA methyltransferase N-terminal
Damage-control phosphatase ARMT1-like metal-binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Release factor glutamine methyltransferase N-terminal
Type II secretion system protein GspC N-terminal
Mannose-6-phosphate isomerase type II C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Important for substrate binding and specificity
Alanyl-transfer RNA synthetases family profile
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Translation elongation factor P/YeiP central
Putative beta-barrel assembly-enhancing protease
DNA polymerase III delta subunit C-terminal
Polysaccharide biosynthesis protein CapD-like
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
Prokaryotic-type class I peptide chain release factors
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Increases nucleophilicity of active site Cys
Arginine decarboxylase C-terminal helical
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Pyruvate phosphate dikinase AMP/ATP-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein uL15/eL18
Flagella basal body P-ring formation protein FlgA
High potential iron-sulfur proteins family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-215); in linked form
Interchain (with Cys-55); in linked form
Transcription elongation factor GreA/GreB N-terminal
DNA replication/recombination mediator RecO N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
ABC-type transport auxiliary lipoprotein component domain-containing protein
Putative regulatory protein FmdB Zinc ribbon
TRAP C4-dicarboxylate transport system permease DctM subunit
Reversibly protonated during proton transport
Pyruvate dehydrogenase E1 component middle
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Membrane fusion protein biotin-lipoyl like
HupH hydrogenase expression protein C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Outer-membrane lipoprotein carrier protein
YbaK/aminoacyl-tRNA synthetase-associated
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Small ribosomal subunit protein uS4 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Choloylglycine hydrolase/NAAA C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cytochrome c-552/4 domain-containing protein
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Type II secretion system protein GspG C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Co-chaperone HscB C-terminal oligomerisation
S-adenosylmethionine-dependent methyltransferase
Magnesium chelatase subunit H N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
O-(3'-phospho-DNA)-tyrosine intermediate
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Thymidylate synthase/dCMP hydroxymethylase
Glycine cleavage T-protein C-terminal barrel
Polysaccharide biosynthesis protein C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Outer membrane lipoprotein-sorting protein
Na+/H+ antiporter MnhB subunit-related protein
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Electron transfer via tryptophanyl radical
Carboxypeptidase regulatory-like domain-containing protein
Type III secretion system flagellar brake protein YcgR PilZN
Urease accessory protein UreH-like transmembrane
Disulphide bond isomerase DsbC/G N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Polymerase/histidinol phosphatase N-terminal
Exonuclease VII large subunit C-terminal
Important for beta-aspartyl-AMP intermediate formation
DNA polymerase III subunit delta C-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Dinitrogenase iron-molybdenum cofactor N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
NADH:ubiquinone oxidoreductase chain 4 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding