Tetrapyrrole biosynthesis uroporphyrinogen III synthase
N-sulphoglucosamine sulphohydrolase C-terminal
Large ribosomal subunit protein bL9 C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
TonB-dependent receptor-like beta-barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Glycoside hydrolase GH146 substrate-binding
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Alpha galactosidase C-terminal beta sandwich
Glycosyl hydrolases family 2 sugar binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Chromosomal replication initiator DnaA C-terminal
Major facilitator superfamily (MFS) profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Shikimate dehydrogenase substrate binding N-terminal
Beta-hexosaminidase bacterial type N-terminal
Transposase IS116/IS110/IS902 C-terminal
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Anthranilate synthase component I N-terminal
Glycine cleavage T-protein C-terminal barrel
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Polysaccharide biosynthesis protein CapD-like
Periplasmic copper-binding protein NosD beta helix
Outer membrane protein beta-barrel domain-containing protein
Polysaccharide biosynthesis protein C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Plays an important role in discriminating NADH against NADPH
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Protochlamydia outer membrane protein domain-containing protein
Integral membrane protein YccS N-terminal
Glycosyl-hydrolase 97 C-terminal oligomerisation
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Alpha-glycerophosphate oxidase C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Cation-transporting P-type ATPase N-terminal
Polymerase/histidinol phosphatase N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Alpha-D-phosphohexomutase alpha/beta/alpha
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycosyltransferase subfamily 4-like N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Inner membrane protein YgaP-like transmembrane
RNA binding; important for wobble base 34 recognition
Choloylglycine hydrolase/NAAA C-terminal
Secretion system C-terminal sorting domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Ribosomal RNA adenine methylase transferase N-terminal
Glycoside hydrolase family 42 N-terminal
Glycoside hydrolase family 42 N-terminal domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Bacterial surface antigen (D15) domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Schiff-base intermediate with substrate; via pyruvic acid
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycosyl hydrolase-like 10 domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Alginate lyase domain-containing protein
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Plays an important role in maintaining the position of the catalytic nucleophile
Polysaccharide chain length determinant N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Pectate lyase superfamily protein domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
S-adenosylmethionine-dependent methyltransferase
PBCV-specific basic adaptor domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Glycerophosphoryl diester phosphodiesterase membrane
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Peptidase M43 pregnancy-associated plasma-A
Large ribosomal subunit protein uL6 alpha-beta
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
ATP-dependent DNA helicase RecG C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Positions MEP for the nucleophilic attack
Organic solvent tolerance-like N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
NfeD-like C-terminal domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glucosamine/galactosamine-6-phosphate isomerase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Carbamoyl-phosphate synthase small subunit N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Translation elongation factor P/YeiP central
Oligogalacturonate lyase domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
3-keto-disaccharide hydrolase domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Sialate O-acetylesterase domain-containing protein
Penicillin-binding protein transpeptidase
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Prokaryotic-type class I peptide chain release factors
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
YMGG-like Gly-zipper domain-containing protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
ABC-type uncharacterised transport system
Tryptophan synthase beta chain-like PALP
SusD/RagB family nutrient-binding outer membrane lipoprotein
NIF system FeS cluster assembly NifU N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Cytochrome c-type biogenesis protein CcmF C-terminal
Important for beta-aspartyl-AMP intermediate formation
N6 adenine-specific DNA methyltransferase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Lysidine-tRNA(Ile) synthetase C-terminal
Limiting CO2-inducible protein B/C beta carbonyic anhydrase
FAD-dependent oxidoreductase 2 FAD binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Reversibly protonated during proton transport
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
6-phosphogluconate dehydrogenase C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Sulfatase-modifying factor enzyme domain-containing protein
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
General stress protein FMN-binding split barrel
Helix-hairpin-helix DNA-binding motif class 1
UDP N-acetylglucosamine O-acyltransferase C-terminal
Type I restriction enzyme R protein N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Signal transduction histidine kinase internal region
Thiosulphate:quinone oxidoreductase small subunit DoxA
Small ribosomal subunit protein uS4 N-terminal
Peptide methionine sulphoxide reductase MsrA
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Beta-hexosaminidase bacterial type N-terminal domain-containing protein
Carboxypeptidase-like regulatory domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Cysteine sulfenic acid (-SOH) intermediate
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Survival protein SurE-like phosphatase/nucleotidase
Ribonucleotide reductase large subunit C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Fibrobacter succinogenes major paralogous
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Electron transfer flavoprotein alpha/beta-subunit N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Phosphomannose isomerase type I catalytic
Na+/H+ antiporter MnhB subunit-related protein
Antitoxin Xre/MbcA/ParS-like toxin-binding
Right handed beta helix domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA pseudouridylate synthase B C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Gly-cisPro motif, important for rejection of L-amino acids
Organic solvent tolerance-like N-terminal domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Urease accessory protein UreH-like transmembrane
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Important for interaction with partner proteins
Trigger factor ribosome-binding bacterial
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Lipocalin-like domain-containing protein
DNA-directed DNA polymerase family A palm
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Pseudouridine synthase I TruA alpha/beta
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Four-carbon acid sugar kinase N-terminal
Glycoside hydrolase family 31 N-terminal
Glycosyl transferase family 3 N-terminal
LPS export ABC transporter periplasmic protein LptC
NIF system FeS cluster assembly NifU C-terminal
DNA replication/recombination mediator RecO N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Tetrahydrodipicolinate-N-succinyltransferase chain A
Membrane fusion protein biotin-lipoyl like
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Proton acceptor; for glutaminase activity
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Heme-copper oxidase subunit III family profile
Transcription elongation factor GreA/GreB N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Important for catalytic activity against all substrates
Important for catalytic activity against dermatan sulfate substrate
Glycosyl hydrolase family 30 beta sandwich
Peptide methionine sulfoxide reductase MsrA
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribonucleotide reductase large subunit N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
DNA mismatch repair proteins mutS family
Nickel transport complex protein, NikM subunit, transmembrane
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Acetyl xylan esterase domain-containing protein
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
Gylcosyl hydrolase 115 C-terminal domain-containing protein
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Putative auto-transporter adhesin head GIN
T9SS C-terminal target domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Large ribosomal subunit protein uL15/eL18
peptide-methionine (R)-S-oxide reductase
Putative oxidoreductase/dehydrogenase Rossmann-like
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Plays an important role in substrate specificity
Aminoacyl-tRNA synthetase class I anticodon-binding