Formamidopyrimidine-DNA glycosylase catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
TonB-dependent receptor-like beta-barrel
RNA polymerase sigma factor 70 region 4 type 2
Major facilitator superfamily (MFS) profile
Beta-hexosaminidase bacterial type N-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycine cleavage T-protein C-terminal barrel
HicB-like antitoxin of toxin-antitoxin system
Gfo/Idh/MocA-like oxidoreductase C-terminal
RNA binding; important for wobble base 34 recognition
Nuclear transport factor 2 family protein
3-keto-disaccharide hydrolase domain-containing protein
Putative auto-transporter adhesin head GIN
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidase M1 membrane alanine aminopeptidase
Glycosyltransferase subfamily 4-like N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Signal transduction histidine kinase internal region
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Lipocalin-like domain-containing protein
Acetylserotonin O-methyltransferase dimerisation
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Transposase IS116/IS110/IS902 C-terminal
Glycoside hydrolase family 31 N-terminal
ABC-type uncharacterised transport system
RND efflux pump membrane fusion protein barrel-sandwich
Peptidase S9 prolyl oligopeptidase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NAD(P) transhydrogenase alpha subunit C-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Urease accessory protein UreH-like transmembrane
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Polysaccharide biosynthesis protein C-terminal
Polysaccharide chain length determinant N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Positions MEP for the nucleophilic attack
Glycoside hydrolase family 13 N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Peptidase C14 caspase domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Gliding motility-associated C-terminal domain-containing protein
Tryptophan synthase beta chain-like PALP
SusD/RagB family nutrient-binding outer membrane lipoprotein
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Type I restriction enzyme R protein N-terminal
T9SS type A sorting domain-containing protein
Secretion system C-terminal sorting domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Carboxypeptidase-like regulatory domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL6 alpha-beta
N-acetylneuraminic acid synthase N-terminal
Chitobiase/beta-hexosaminidases N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Heme-copper oxidase subunit III family profile
Translation elongation factor P/YeiP central
General stress protein FMN-binding split barrel
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Trigger factor ribosome-binding bacterial
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Phosphatidate phosphatase APP1 catalytic
Glycoside hydrolase family 42 N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ATP-dependent DNA helicase RecG C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Phosphatidic acid phosphatase type 2/haloperoxidase
Neutral/alkaline non-lysosomal ceramidase N-terminal domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glucosamine/galactosamine-6-phosphate isomerase
Ribose-phosphate pyrophosphokinase N-terminal
NIF system FeS cluster assembly NifU C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Gp5/Type VI secretion system Vgr protein OB-fold
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Phosphodiester glycosidase domain-containing protein
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Cytochrome C Planctomycete-type domain-containing protein
PhoD-like phosphatase metallophosphatase
DNA topoisomerase I catalytic core eukaryotic-type
Bacterial transcription activator effector binding
Prokaryotic-type class I peptide chain release factors
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Right handed beta helix domain-containing protein
Outer membrane lipoprotein-sorting protein
N6 adenine-specific DNA methyltransferase N-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Membrane fusion protein biotin-lipoyl like
Moybdenum cofactor oxidoreductase dimerisation
Schiff-base intermediate with substrate; via pyruvic acid
Activator of Hsp90 ATPase homologue 1-like C-terminal
Type I restriction modification DNA specificity
AMP-activated protein kinase glycogen-binding
Microcin J25-processing protein McjB C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL15/eL18
PBCV-specific basic adaptor domain-containing protein
Homogentisate 1,2-dioxygenase N-terminal
BAAT/Acyl-CoA thioester hydrolase C-terminal
Leucine-rich repeat domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Ppx/GppA phosphatase domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Polysaccharide biosynthesis protein CapD-like
Thymidylate synthase/dCMP hydroxymethylase
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Resolvase/invertase-type recombinase catalytic
UDP N-acetylglucosamine O-acyltransferase C-terminal
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
DNA-directed RNA polymerase subunit delta
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Gluconate 2-dehydrogenase subunit 3 family protein
Peptidase S12 Pab87-related C-terminal domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Malonate/sodium symporter MadM subunit N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyl transferase family 3 N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
S-adenosylmethionine-dependent methyltransferase
TonB-dependent receptor plug domain-containing protein
Conserved virulence factor B-like winged helix
Type IX secretion system protein PorV domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cation-transporting P-type ATPase C-terminal
Cation-transporting P-type ATPase N-terminal
Cellulase Ig-like domain-containing protein
Inward rectifier potassium channel C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Penicillin-binding protein transpeptidase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Phosphoribosylformylglycinamidine synthase linker
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Biopterin-dependent aromatic amino acid hydroxylase family profile
Neutral/alkaline non-lysosomal ceramidase N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Sodium/calcium exchanger membrane region
Glycoside hydrolase GH146 substrate-binding
Transition state stabilizer; via amide nitrogen
Release factor glutamine methyltransferase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Beta-hexosaminidase bacterial type N-terminal domain-containing protein
DNA-directed DNA polymerase family A palm
Organic solvent tolerance-like N-terminal
Glucose/Sorbosone dehydrogenase domain-containing protein
Gliding motility protein SprA N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Schiff-base intermediate with acetaldehyde
SGNH hydrolase-type esterase domain-containing protein
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Putative auto-transporter adhesin head GIN domain-containing protein
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Large ribosomal subunit protein uL2 C-terminal
Translation elongation factor EFTs/EF1B dimerisation
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-111)
Putative beta-lactamase-inhibitor-like PepSY-like
Essential for prephenate dehydratase activity
DNA replication/recombination mediator RecO N-terminal
Important for interaction with partner proteins
Putative adhesin domain-containing protein
Thiopeptide-type bacteriocin biosynthesis
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
BREX system Lon protease-like BrxL N-terminal
Electron transfer via tryptophanyl radical
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Bacterial alpha-L-rhamnosidase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Proton acceptor; for glutaminase activity
DNA mismatch repair proteins mutS family
Thiamine pyrophosphate enzyme TPP-binding
Pectate lyase superfamily protein domain-containing protein
Putative exodeoxyribonuclease 8 PDDEXK-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Mandelate racemase/muconate lactonizing enzyme N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
ATP synthase F1 complex delta/epsilon subunit N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Lysidine-tRNA(Ile) synthetase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Gamma-glutamylcyclotransferase AIG2-like
Endoribonuclease L-PSP/chorismate mutase-like
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Carbohydrate-binding domain-containing protein
Alanyl-transfer RNA synthetases family profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Chromosomal replication initiator DnaA C-terminal
Saccharopine dehydrogenase-like C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
N-end rule aminoacyl transferase C-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Inner membrane protein YgaP-like transmembrane
Cationic amino acid transporter C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
TonB C-terminal domain-containing protein
Reversibly protonated during proton transport
O-(3'-phospho-DNA)-tyrosine intermediate
Plays an important role in maintaining the position of the catalytic nucleophile
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Alpha-glycerophosphate oxidase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glutathionylspermidine synthase pre-ATP-grasp-like
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pseudouridine synthase I TruA alpha/beta
Cellulose-binding Sde182 nucleoside hydrolase-like
Cellulose-binding Sde182 nucleoside hydrolase-like domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidase M15C domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
2-oxoacid dehydrogenase acyltransferase catalytic
Small ribosomal subunit protein uS4 N-terminal
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Plays an important role in substrate specificity
Thiamin pyrophosphokinase thiamin-binding
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Glycoside hydrolase family 65 N-terminal domain-containing protein
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal