RND efflux pump membrane fusion protein barrel-sandwich
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
TonB-dependent receptor-like beta-barrel
Transposase IS116/IS110/IS902 C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Peptidase M1 membrane alanine aminopeptidase
Glucose-methanol-choline oxidoreductase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Peptidase S9 prolyl oligopeptidase catalytic
Pectate lyase superfamily protein domain-containing protein
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Membrane fusion protein biotin-lipoyl like
Secretion system C-terminal sorting domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Pseudouridine synthase I TruA alpha/beta
Major facilitator superfamily (MFS) profile
NIF system FeS cluster assembly NifU N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Gliding motility-associated C-terminal domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Tryptophan synthase beta chain-like PALP
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Signal transduction histidine kinase internal region
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Exonuclease VII large subunit C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
S-adenosylmethionine-dependent methyltransferase
Aminoacyl-transfer RNA synthetases class-II family profile
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Carbamoyl-phosphate synthetase large subunit-like ATP-binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Periplasmic copper-binding protein NosD beta helix
Periplasmic copper-binding protein NosD beta helix domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Lipocalin-like domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Cation-transporting P-type ATPase N-terminal
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Peptidoglycan recognition protein family
Glycosyl transferase family 3 N-terminal
Outer membrane lipoprotein-sorting protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Alpha-glycerophosphate oxidase C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Nitrite/Sulfite reductase ferredoxin-like
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
ATP-dependent DNA helicase RecG C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Phosphoribosylformylglycinamidine synthase linker
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Heavy metal transport/detoxification protein
RNA 2-O ribose methyltransferase substrate binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Anthranilate synthase component I N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
N-end rule aminoacyl transferase C-terminal
Beta-galactosidase trimerisation domain-containing protein
Transition state stabilizer; via amide nitrogen
Glycoside hydrolase family 57 N-terminal
NIF system FeS cluster assembly NifU C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
3-beta hydroxysteroid dehydrogenase/isomerase
Peptidase MA-like domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase M15C domain-containing protein
Reversibly protonated during proton transport
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Lantibiotic biosynthesis protein dehydration
Pyrroline-5-carboxylate reductase catalytic N-terminal
BREX system Lon protease-like BrxL N-terminal
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal domain-containing protein
SusD/RagB family nutrient-binding outer membrane lipoprotein
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Polysaccharide biosynthesis protein C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glucose-methanol-choline oxidoreductase C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
N-sulphoglucosamine sulphohydrolase C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
RNA binding; important for wobble base 34 recognition
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
peptide-methionine (R)-S-oxide reductase
Type I restriction modification DNA specificity
Transglutaminase domain-containing protein
Cytochrome b561 bacterial/Ni-hydrogenase
Shikimate dehydrogenase substrate binding N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
DNA mismatch repair proteins mutS family
Important for beta-aspartyl-AMP intermediate formation
PhoD-like phosphatase metallophosphatase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
WD40-like beta Propeller containing protein
3-keto-disaccharide hydrolase domain-containing protein
Peptidase M43 pregnancy-associated plasma-A
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Right handed beta helix domain-containing protein
Glycosyl transferase family 28 C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Inward rectifier potassium channel C-terminal
Penicillin-binding protein transpeptidase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
O-(5'-phospho-DNA)-tyrosine intermediate
Carbamoyl-phosphate synthase small subunit N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Inosine/uridine-preferring nucleoside hydrolase
Prokaryotic-type class I peptide chain release factors
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Twin-arginine translocation pathway signal
Glycosyltransferase family 28 N-terminal
Peptidase M17 leucyl aminopeptidase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Gly-cisPro motif, important for rejection of L-amino acids
Formamidopyrimidine-DNA glycosylase catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Tetrahydrodipicolinate-N-succinyltransferase chain A
DNA-directed DNA polymerase family A palm
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Heme-copper oxidase subunit III family profile
Auto-transporter adhesin head GIN domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Heavy metal binding domain-containing protein
Sortilin N-terminal domain-containing protein
Thiamine pyrophosphate enzyme TPP-binding
LamG domain protein jellyroll fold domain protein
Contractile injection system tube protein N-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Glycosyl-hydrolase 97 C-terminal oligomerisation
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycosyl hydrolase family 30 beta sandwich
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycoside hydrolase family 31 N-terminal
Tetratricopeptide TPR_1 repeat-containing protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Lysidine-tRNA(Ile) synthetase C-terminal
4'-phosphopantetheinyl transferase N-terminal
Large ribosomal subunit protein uL15/eL18
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Nuclear transport factor 2 family protein
Probable endolytic peptidoglycan transglycosylase RlpA
Bacterial bifunctional deaminase-reductase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Fibrobacter succinogenes major paralogous
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Translation initiation factor beta propellor-like
Type IX secretion system protein PorV domain-containing protein
Gamma-glutamylcyclotransferase AIG2-like
Peptide methionine sulfoxide reductase MsrB
Phosphomannose isomerase type I catalytic
Glycerophosphoryl diester phosphodiesterase
Acyl-CoA dehydrogenase N-terminal bacteria
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Membrane protein involved in aromatic hydrocarbon degradation
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Glutathionylspermidine synthase pre-ATP-grasp-like
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Glycoside hydrolase family 13 N-terminal
Peptide methionine sulphoxide reductase MsrA
Secretin/TonB short N-terminal domain-containing protein
Sialate O-acetylesterase domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Translation elongation factor P/YeiP central
Arabinogalactan endo-beta-1,4-galactanase
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Proton acceptor; for glutaminase activity
Alginate lyase domain-containing protein
Histidine-specific methyltransferase SAM-dependent
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Beta-xylosidase C-terminal Concanavalin A-like
Saccharopine dehydrogenase-like C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
DNA replication/recombination mediator RecO N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Carbohydrate metabolism domain-containing protein
T9SS C-terminal target domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Sodium/calcium exchanger membrane region
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Alginate export domain-containing protein
5-glutamyl coenzyme A thioester intermediate
Glycine cleavage T-protein C-terminal barrel
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Plays an important role in substrate specificity
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Beta-hexosaminidase bacterial type N-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
T9SS type B sorting domain-containing protein
Glycosyl hydrolase-like 10 domain-containing protein
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Glucose/Sorbosone dehydrogenase domain-containing protein
Insecticide toxin TcdB middle/C-terminal
Insecticide toxin TcdB middle/N-terminal
Large ribosomal subunit protein uL6 alpha-beta
ABC-type uncharacterised transport system
Neurotransmitter-gated ion-channel ligand-binding domain-containing protein
Important for interaction with partner proteins
Membrane insertase YidC/Oxa/ALB C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Small ribosomal subunit protein uS4 N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Glycosyl hydrolases family 38 C-terminal beta sandwich
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Electron transfer via tryptophanyl radical
Glycoside hydrolase GH146 substrate-binding
Glycoside hydrolase GH146 substrate-binding domain-containing protein
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Cationic amino acid transporter C-terminal
Type 1 periplasmic binding fold superfamily protein
Surface glycan-binding protein B xyloglucan binding
Inner membrane protein YgaP-like transmembrane
Ribonucleotide reductase large subunit C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Carboxypeptidase-like regulatory domain-containing protein
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Urease accessory protein UreH-like transmembrane
Cytochrome P460 domain-containing protein
Type I restriction enzyme R protein N-terminal
Gliding motility-associated lipoprotein GldH
Ribose-phosphate pyrophosphokinase N-terminal
Serine aminopeptidase S33 domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Gliding motility protein SprA N-terminal
Gliding motility protein SprA N-terminal domain-containing protein
ssDNA thymidine ADP-ribosyltransferase DarT
Copper type II ascorbate-dependent monooxygenase C-terminal
Copper type II ascorbate-dependent monooxygenase N-terminal
Schiff-base intermediate with acetaldehyde
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidase C1A papain C-terminal domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Malonate/sodium symporter MadM subunit N-terminal
Glycoamylase-like domain-containing protein
Peptide methionine sulfoxide reductase MsrA
Pyrroline-5-carboxylate reductase dimerisation
Gliding motility-associated lipoprotein GldD
O-(3'-phospho-DNA)-tyrosine intermediate
AB hydrolase-1 domain-containing protein
Glycoside hydrolase family 5 domain-containing protein
BAAT/Acyl-CoA thioester hydrolase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Important for autoinhibition of adenylyltransferase activity
Gp5/Type VI secretion system Vgr protein OB-fold
Chromosomal replication initiator DnaA C-terminal
Organic solvent tolerance-like N-terminal
Trigger factor ribosome-binding bacterial
Bacterial transcription activator effector binding
CASTOR/POLLUX/SYM8 ion channel conserved