Outer membrane protein beta-barrel domain-containing protein
Solute-binding protein family 3/N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Restriction endonuclease type II DpnII-like
Pyruvate phosphate dikinase AMP/ATP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aminoacyl-transfer RNA synthetases class-II family profile
Ribosomal RNA small subunit methyltransferase E methyltransferase
Polymerase/histidinol phosphatase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Trigger factor ribosome-binding bacterial
Serine aminopeptidase S33 domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aldehyde ferredoxin oxidoreductase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Beta-hexosaminidase bacterial type N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
O-(3'-phospho-DNA)-tyrosine intermediate
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
S-adenosylmethionine-dependent methyltransferase
DNA replication/recombination mediator RecO N-terminal
Thiamin pyrophosphokinase thiamin-binding
Plays an important role in discriminating NADH against NADPH
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
RNA polymerase sigma factor 70 region 4 type 2
Exonuclease VII large subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
ABC transporter substrate-binding protein PnrA-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Tryptophan synthase beta chain-like PALP
NIF system FeS cluster assembly NifU N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Gly-cisPro motif, important for rejection of L-amino acids
Glycine cleavage T-protein C-terminal barrel
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
ATP-dependent DNA helicase RecG C-terminal
Proton acceptor; for glutaminase activity
Penicillin-binding protein transpeptidase
Putative acyltransferase ACT14924-like acyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Translation elongation factor P/YeiP central
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Interaction with polymerase core subunit RpoC
DNA-directed DNA polymerase family A palm
Pyridoxamine 5'-phosphate oxidase putative
Resolvase/invertase-type recombinase catalytic
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL2 C-terminal
Probable transposase IS891/IS1136/IS1341
Phosphotransferase system enzyme I N-terminal
Major facilitator superfamily (MFS) profile
O-(phosphoribosyl dephospho-coenzyme A)serine
RNA 2-O ribose methyltransferase substrate binding
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glucose-6-phosphate isomerase prokaryote
Carbamoyl-phosphate synthase small subunit N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Small ribosomal subunit protein uS4 N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Plays an important role in substrate specificity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA mismatch repair proteins mutS family
Alanyl-transfer RNA synthetases family profile
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Cation-transporting P-type ATPase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Important for interaction with partner proteins
Survival protein SurE-like phosphatase/nucleotidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Important for autoinhibition of adenylyltransferase activity
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
FAD-dependent oxidoreductase 2 FAD binding
NIF system FeS cluster assembly NifU C-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Prokaryotic-type class I peptide chain release factors
Glycosyl-hydrolase 97 C-terminal oligomerisation
Chromosomal replication initiator DnaA C-terminal
RlpA-like protein double-psi beta-barrel
Lysidine-tRNA(Ile) synthetase C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Cyclophilin-like domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Phosphomannose isomerase type I catalytic
Involved in ionization of N3 of dUMP, leading to its activation
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RND efflux pump membrane fusion protein barrel-sandwich
Large ribosomal subunit protein uL15/eL18
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Important for beta-aspartyl-AMP intermediate formation
Ribosome maturation factor RimP N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glucosamine/galactosamine-6-phosphate isomerase
Ribose-phosphate pyrophosphokinase N-terminal
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding