Organic solvent tolerance-like N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA mismatch repair proteins mutS family
Bacterial repeat domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Glycosyltransferase subfamily 4-like N-terminal
Essential for prephenate dehydratase activity
Small ribosomal subunit protein uS4 N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL15/eL18
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with acetaldehyde
Magnesium transporter MgtE intracellular
Septum formation inhibitor MinC C-terminal
Major facilitator superfamily (MFS) profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
Bacterial bifunctional deaminase-reductase C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ppx/GppA phosphatase domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
tRNA (guanine-N(1)-)-methyltransferase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Pyruvate phosphate dikinase AMP/ATP-binding
Tryptophan synthase beta chain-like PALP
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Glycine zipper 2TM domain-containing protein
Proton acceptor; for glutaminase activity
Heme-copper oxidase subunit III family profile
Aminoacyl-transfer RNA synthetases class-II family profile
Myo-inositol-1-phosphate synthase GAPDH-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Penicillin-binding protein transpeptidase
Cytochrome b561 bacterial/Ni-hydrogenase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Flagellar motor switch protein FliN-like C-terminal
Thiamine pyrophosphate enzyme TPP-binding
RNA 2-O ribose methyltransferase substrate binding
Gly-cisPro motif, important for rejection of L-amino acids
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL2 C-terminal
Trigger factor ribosome-binding bacterial
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Cysteine sulfenic acid (-SOH) intermediate
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Polymerase/histidinol phosphatase N-terminal
Glycoside hydrolase family 57 N-terminal
Phosphoadenosine phosphosulphate reductase
Important for beta-aspartyl-AMP intermediate formation
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase 30kDa subunit
Inner membrane protein YgaP-like transmembrane
RND efflux pump membrane fusion protein barrel-sandwich
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Prepilin type IV endopeptidase peptidase
HupH hydrogenase expression protein C-terminal
Membrane fusion protein biotin-lipoyl like
Aspartate/homoserine dehydrogenase NAD-binding
Glycoside-hydrolase family GH114 TIM-barrel
Plays an important role in substrate specificity
Cation-transporting P-type ATPase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
NIF system FeS cluster assembly NifU C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Important for interaction with partner proteins
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
TonB-dependent receptor-like beta-barrel
SMODS-associated and fused to various effectors
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Disulphide bond isomerase DsbC/G N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Translation elongation factor P/YeiP central
Bacterial type II secretion system protein E
Anthranilate synthase component I N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Large ribosomal subunit protein uL6 alpha-beta
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Signal transduction histidine kinase internal region
Transcription factor NikR nickel binding C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
HicB-like antitoxin of toxin-antitoxin system
CRISPR-associated protein Cmr2 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RlpA-like protein double-psi beta-barrel
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Superoxide dismutase copper/zinc binding
Alanyl-transfer RNA synthetases family profile
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
RNA binding; important for wobble base 34 recognition
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Flagellar assembly protein FliH/Type III secretion system HrpE
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
Carbamoyl-phosphate synthase small subunit N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
L-cysteine S-thiosulfotransferase subunit SoxA
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
PhoD-like phosphatase metallophosphatase
Reversibly protonated during proton transport
Positions MEP for the nucleophilic attack
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Helix-hairpin-helix DNA-binding motif class 1
Prokaryotic-type class I peptide chain release factors
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Involved in allosteric activation by GTP
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Important for guanine/8-oxoguanine distinction
Pyridoxamine 5'-phosphate oxidase putative
Transcription regulator AsnC/Lrp ligand binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Cytochrome C biogenesis protein transmembrane
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
ATP-grasp fold succinyl-CoA synthetase-type
Chromosomal replication initiator DnaA C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycyl cysteine dithioester (Cys-Gly) (interchain with G-Cter in ThiS)
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Type I restriction modification DNA specificity
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
6-phosphogluconate dehydrogenase C-terminal
Type II secretion system protein GspG C-terminal
Glycosyl transferase family 3 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)