Tryptophan synthase beta chain-like PALP
S-adenosylmethionine-dependent methyltransferase
Putative regulatory protein FmdB Zinc ribbon
NIF system FeS cluster assembly NifU N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Aminoacyl-transfer RNA synthetases class-II family profile
Gamma-butyrobetaine hydroxylase-like N-terminal
Transposase IS116/IS110/IS902 C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RNA polymerase sigma factor 70 region 4 type 2
Flagellar assembly protein FliH/Type III secretion system HrpE
O-(5'-phospho-DNA)-tyrosine intermediate
Activator of Hsp90 ATPase homologue 1-like C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Flagellar Assembly Protein A N-terminal region
UDP N-acetylglucosamine O-acyltransferase C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ribose-phosphate pyrophosphokinase N-terminal
Alanyl-transfer RNA synthetases family profile
SUF system FeS cluster assembly SufBD N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Penicillin-binding protein transpeptidase
Replication initiation protein-like C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Exonuclease VII large subunit C-terminal
Major facilitator superfamily (MFS) profile
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Membrane insertase YidC/Oxa/ALB C-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Reversibly protonated during proton transport
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
NADH:ubiquinone oxidoreductase 30kDa subunit
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Important for substrate specificity; cannot use PPi as phosphoryl donor
Large ribosomal subunit protein uL2 C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Release factor glutamine methyltransferase N-terminal
Glycosyl transferase family 3 N-terminal
DNA mismatch repair proteins mutS family
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Phage terminase large subunit GpA ATPase
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Flagellar hook-length control protein-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Sporulation stage II protein D amidase enhancer LytB N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Predicted DNA-binding protein ribbon-helix-helix
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Type I restriction modification DNA specificity
Polysaccharide biosynthesis protein CapD-like
Bacterial type II secretion system protein E
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Surface lipoprotein of Spirochaetales order
N6 adenine-specific DNA methyltransferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
RNA binding; important for wobble base 34 recognition
Survival protein SurE-like phosphatase/nucleotidase
TonB-dependent receptor-like beta-barrel
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Urease accessory protein UreH-like transmembrane
Phosphomannose isomerase type I catalytic
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
RNA 2-O ribose methyltransferase substrate binding
Carbamoyl-phosphate synthase small subunit N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
PHA accumulation regulator DNA-binding N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Transcriptional coactivator p15 (PC4) C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Membrane fusion protein biotin-lipoyl like
Solute-binding protein family 3/N-terminal
Essential for prephenate dehydratase activity
Polysaccharide biosynthesis protein C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
TNF family profile domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Prepilin type IV endopeptidase peptidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Important for interaction with partner proteins
Prokaryotic-type class I peptide chain release factors
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Bacterial transcription activator effector binding
FAD-dependent oxidoreductase 2 FAD binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
N-end rule aminoacyl transferase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Type II secretion system protein GspG C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Endoribonuclease L-PSP/chorismate mutase-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Ribosomal RNA small subunit methyltransferase E methyltransferase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Adaptive response protein AidB N-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Proton acceptor; for glutaminase activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
ABC-type uncharacterised transport system
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA-directed DNA polymerase family A palm
Aconitase A/isopropylmalate dehydratase small subunit swivel
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Trigger factor ribosome-binding bacterial
Nitrite/Sulfite reductase ferredoxin-like
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glycoside hydrolase family 42 N-terminal
N-acetylneuraminic acid synthase N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
PhoD-like phosphatase metallophosphatase
Large ribosomal subunit protein uL15/eL18
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidase M1 membrane alanine aminopeptidase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
DNA helicase Holliday junction RuvA type
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Phosphoribosylformylglycinamidine synthase linker
NADH:ubiquinone oxidoreductase-like 20kDa subunit
AMP-activated protein kinase glycogen-binding
DNA replication/recombination mediator RecO N-terminal
Positions MEP for the nucleophilic attack
Anaphase-promoting complex, cyclosome, subunit 3
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Large ribosomal subunit protein uL6 alpha-beta
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Interacts with tRNA; defines subfamily-specific binding signature
Heme-copper oxidase subunit III family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Plays an important role in substrate specificity
DNA/pantothenate metabolism flavoprotein C-terminal