ATP synthase F1 complex delta/epsilon subunit N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Major facilitator superfamily (MFS) profile
ABC transporter substrate-binding protein PnrA-like
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Chromosomal replication initiator DnaA C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Polymerase/histidinol phosphatase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Ribosomal RNA adenine methylase transferase N-terminal
Stage III sporulation protein AA AAA+ ATPase
Cytochrome b561 bacterial/Ni-hydrogenase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Restriction endonuclease AspBHI N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Prepilin type IV endopeptidase peptidase
O-(3'-phospho-DNA)-tyrosine intermediate
Sporulation stage IV protein A C-terminal
Flagellar hook-length control protein-like C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Membrane fusion protein biotin-lipoyl like
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Penicillin-binding protein transpeptidase
Cytochrome oxidase subunit II copper A binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Involved in allosteric activation by GTP
Pyridoxamine 5'-phosphate oxidase putative
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Anthranilate synthase component I N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Polysaccharide biosynthesis protein CapD-like
YbaK/aminoacyl-tRNA synthetase-associated
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Plays an important role in substrate specificity
Gly-cisPro motif, important for rejection of L-amino acids
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Sugar fermentation stimulation protein C-terminal
RNA 2-O ribose methyltransferase substrate binding
Alanyl-transfer RNA synthetases family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Dinitrogenase iron-molybdenum cofactor biosynthesis
Small ribosomal subunit protein uS4 N-terminal
Threonine/serine exporter-like N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
CobB/CobQ-like glutamine amidotransferase
Phosphoribosylformylglycinamidine synthase linker
Glycosyltransferase subfamily 4-like N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cation-transporting P-type ATPase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
NTF2-like N-terminal transpeptidase domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Tryptophan synthase beta chain-like PALP
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Nitrite/Sulfite reductase ferredoxin-like
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Sodium/calcium exchanger membrane region
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Cytochrome C biogenesis protein transmembrane
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Sporulation stage II protein D amidase enhancer LytB N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Putative oxidoreductase/dehydrogenase Rossmann-like
TRAP C4-dicarboxylate transport system permease DctM subunit
D-galactarate/Altronate dehydratase C-terminal
Glycosyltransferase family 28 N-terminal
serine-type D-Ala-D-Ala carboxypeptidase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aldehyde ferredoxin oxidoreductase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Important for interaction with partner proteins
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
tRNA pseudouridylate synthase B C-terminal
Transcription regulator AsnC/Lrp ligand binding
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA mismatch repair proteins mutS family
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADH:ubiquinone oxidoreductase 30kDa subunit
ABC-type glycine betaine transport system substrate-binding
O-(phosphoribosyl dephospho-coenzyme A)serine
Type II secretion system protein GspG C-terminal
Thiamin pyrophosphokinase thiamin-binding
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Membrane iron-sulfur containing protein FtrD-like
Increases nucleophilicity of active site Cys
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Schiff-base intermediate with D-ribose 5-phosphate
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Dipicolinate synthase subunit A N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Translation elongation factor P/YeiP central
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Tripartite tricarboxylate transporter substrate binding protein
Flagellar motor switch protein FliN-like C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Formylmethanofuran dehydrogenase subunit E
Carbohydrate-binding domain-containing protein
Predicted pPIWI-associating nuclease group 2
Phosphatidylglycerol lysyltransferase C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Large ribosomal subunit protein uL15/eL18
Transposase IS116/IS110/IS902 C-terminal
Release factor glutamine methyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Bacterial type II secretion system protein E
Carbamoyl-phosphate synthase small subunit N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Pseudouridine synthase I TruA alpha/beta
Polysaccharide biosynthesis protein C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cell envelope-related transcriptional attenuator
nitrite reductase (cytochrome; ammonia-forming)
Could be important to modulate the pK values of the two catalytic cysteine residues
Membrane insertase YidC/Oxa/ALB C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
HicB-like antitoxin of toxin-antitoxin system
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Interaction with polymerase core subunit RpoC
Cytochrome b/b6 C-terminal region profile
Important for beta-aspartyl-AMP intermediate formation
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucosamine/galactosamine-6-phosphate isomerase
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Resolvase/invertase-type recombinase catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ferrous iron transport protein B C-terminal
Glycosyl transferase family 3 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
DNA replication/recombination mediator RecO N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Moybdenum cofactor oxidoreductase dimerisation
Methylene-tetrahydrofolate reductase C-terminal
Menaquinone biosynthesis protein MenD middle
RsbT co-antagonist protein RsbRD N-terminal
2-oxoacid dehydrogenase acyltransferase catalytic
Dihydrodipicolinate reductase N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Na+/H+ antiporter MnhB subunit-related protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Reversibly protonated during proton transport
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Regulator of nucleoside diphosphate kinase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
RNA binding; important for wobble base 34 recognition
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Sporulation transcription regulator WhiA N-terminal
Glycine cleavage T-protein C-terminal barrel
Quercetin 2,3-dioxygenase C-terminal cupin
NIF system FeS cluster assembly NifU N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Exonuclease VII large subunit C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Could play a key role in the communication between the regulatory and the substrate sites
Dihydrodipicolinate reductase C-terminal
Essential for prephenate dehydratase activity
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Saccharopine dehydrogenase-like C-terminal