DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
ABC-type uncharacterised transport system
Proton acceptor; for glutaminase activity
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
TonB-dependent receptor-like beta-barrel
Thymidylate synthase/dCMP hydroxymethylase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
6-phosphogluconate dehydrogenase C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glucosamine/galactosamine-6-phosphate isomerase
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Pyridoxamine 5'-phosphate oxidase putative
Molybdopterin cofactor biosynthesis C (MoaC)
Glycoside hydrolase family 57 N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL2 C-terminal
Penicillin-binding protein transpeptidase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Endolytic peptidoglycan transglycosylase RlpA
YbaK/aminoacyl-tRNA synthetase-associated
Arginine decarboxylase C-terminal helical
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
O-(5'-phospho-DNA)-tyrosine intermediate
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Alginate export domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL6 alpha-beta
Glycosyltransferase subfamily 4-like N-terminal
Chalcone isomerase domain-containing protein
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Membrane fusion protein biotin-lipoyl like
Disulphide bond isomerase DsbC/G N-terminal
Interaction with polymerase core subunit RpoC
Type IV secretion system coupling protein TraD DNA-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Carbamoyl-phosphate synthase small subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Transglycosylase SLT domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
Flagellar hook-length control protein-like C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Type I restriction modification DNA specificity
SUF system FeS cluster assembly SufBD N-terminal
DNA-directed DNA polymerase family A palm
Anthranilate synthase component I N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Outer membrane protein assembly factor BamD
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Flagellar motor switch protein FliN-like C-terminal
Important for interaction with partner proteins
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Positions MEP for the nucleophilic attack
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Flagellar basal body rod protein N-terminal
Thiol:disulfide interchange protein DsbD
Exonuclease VII large subunit C-terminal
Lytic transglycosylase superhelical linker
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Prepilin type IV endopeptidase peptidase
Helix-hairpin-helix DNA-binding motif class 1
Outer membrane protein assembly factor BamA
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoadenosine phosphosulphate reductase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Major facilitator superfamily (MFS) profile
Solute-binding protein family 3/N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Could play a key role in the communication between the regulatory and the substrate sites
Cob(I)alamin adenosyltransferase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Essential for prephenate dehydratase activity
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Flagellar basal-body/hook protein C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Putative regulatory protein FmdB Zinc ribbon
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Flagella basal body P-ring formation protein FlgA
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glutamate synthase alpha subunit C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
4'-phosphopantetheinyl transferase N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Membrane insertase YidC/Oxa/ALB C-terminal
Putative beta-barrel assembly-enhancing protease
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Urease accessory protein UreH-like transmembrane
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Nucleophile; cysteine thiosulfonate intermediate
Transcription elongation factor GreA/GreB N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Release factor glutamine methyltransferase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Tryptophan synthase beta chain-like PALP
Small ribosomal subunit protein uS4 N-terminal
Peptide methionine sulphoxide reductase MsrA
ABC-type transport auxiliary lipoprotein component
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Required for zinc-mediated homotetramerization and catalytic activity
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
DNA mismatch repair proteins mutS family
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Alanyl-transfer RNA synthetases family profile
N6 adenine-specific DNA methyltransferase N-terminal
Methanol dehydrogenase [cytochrome c] subunit 2
Aminoacyl-tRNA synthetase class I anticodon-binding
NIF system FeS cluster assembly NifU N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
EfeO-type cupredoxin-like domain-containing protein
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-103)
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA replication/recombination mediator RecO N-terminal
Electron transfer via tryptophanyl radical
Ribosomal RNA adenine methylase transferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Chromosomal replication initiator DnaA C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Lipocalin-like domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Polysaccharide biosynthesis protein C-terminal
Glycosyl transferase family 3 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Gamma-glutamylcyclotransferase AIG2-like
Phosphotransferase system enzyme I N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-97)
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Saccharopine dehydrogenase-like C-terminal
Prokaryotic-type class I peptide chain release factors
Type 4 fimbrial biogenesis protein PilX N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Tetrahydrodipicolinate-N-succinyltransferase chain A
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Nitrite/Sulfite reductase ferredoxin-like
Gly-cisPro motif, important for rejection of L-amino acids
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ATP synthase F1 complex delta/epsilon subunit N-terminal
Virulence factor membrane-bound polymerase C-terminal
Survival protein SurE-like phosphatase/nucleotidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Translation elongation factor P/YeiP central
Reversibly protonated during proton transport
Lysidine-tRNA(Ile) synthetase C-terminal
Organic solvent tolerance-like N-terminal
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL15/eL18
Dicarboxylate transport domain-containing protein
Outer-membrane lipoprotein carrier protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Restriction endonuclease type I HsdR N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal